adn 138 has been researched along with tolrestat in 1 studies
| Studies (adn 138) | Trials (adn 138) | Recent Studies (post-2010) (adn 138) | Studies (tolrestat) | Trials (tolrestat) | Recent Studies (post-2010) (tolrestat) |
|---|---|---|---|---|---|
| 5 | 0 | 0 | 198 | 25 | 14 |
| Protein | Taxonomy | adn 138 (IC50) | tolrestat (IC50) |
|---|---|---|---|
| Aldo-keto reductase family 1 member B10 | Homo sapiens (human) | 0.0244 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 0.2689 | |
| Aldo-keto reductase family 1 member A1 | Homo sapiens (human) | 1.1533 | |
| Aldo-keto reductase family 1 member B1 | Homo sapiens (human) | 0.2303 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.096 | |
| Aldo-keto reductase family 1 member B1 | Bos taurus (cattle) | 0.043 | |
| Aldo-keto reductase family 1 member A1 | Sus scrofa (pig) | 1.365 | |
| Aldo-keto reductase family 1 member A1 | Rattus norvegicus (Norway rat) | 1.21 | |
| Aldo-keto reductase family 1 member B1 | Sus scrofa (pig) | 0.0225 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.03 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dietrich, A; Harrison, MC; Hohman, TC; McCaleb, M; Millen, J; Sredy, J; Sullivan, D; Woolson, SA; Wrobel, J | 1 |
1 other study(ies) available for adn 138 and tolrestat
| Article | Year |
|---|---|
Novel spirosuccinimides with incorporated isoindolone and benzisothiazole 1,1-dioxide moieties as aldose reductase inhibitors and antihyperglycemic agents.
Topics: Aldehyde Reductase; Animals; Blood Glucose; Cattle; Diabetes Mellitus, Experimental; Glyceraldehyde; Hypoglycemic Agents; Indoles; Male; Mice; Mice, Inbred C57BL; Molecular Structure; Rats; Structure-Activity Relationship; Succinimides; Thiazoles; Thiazolidinediones | 1992 |