Page last updated: 2024-09-03

adn 138 and tolrestat

adn 138 has been researched along with tolrestat in 1 studies

Compound Research Comparison

Studies
(adn 138)
Trials
(adn 138)
Recent Studies (post-2010)
(adn 138)
Studies
(tolrestat)
Trials
(tolrestat)
Recent Studies (post-2010) (tolrestat)
5001982514

Protein Interaction Comparison

ProteinTaxonomyadn 138 (IC50)tolrestat (IC50)
Aldo-keto reductase family 1 member B10Homo sapiens (human)0.0244
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)0.2689
Aldo-keto reductase family 1 member A1Homo sapiens (human)1.1533
Aldo-keto reductase family 1 member B1Homo sapiens (human)0.2303
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.096
Aldo-keto reductase family 1 member B1Bos taurus (cattle)0.043
Aldo-keto reductase family 1 member A1Sus scrofa (pig)1.365
Aldo-keto reductase family 1 member A1Rattus norvegicus (Norway rat)1.21
Aldo-keto reductase family 1 member B1Sus scrofa (pig)0.0225
Mu-type opioid receptorCavia porcellus (domestic guinea pig)0.03

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dietrich, A; Harrison, MC; Hohman, TC; McCaleb, M; Millen, J; Sredy, J; Sullivan, D; Woolson, SA; Wrobel, J1

Other Studies

1 other study(ies) available for adn 138 and tolrestat

ArticleYear
Novel spirosuccinimides with incorporated isoindolone and benzisothiazole 1,1-dioxide moieties as aldose reductase inhibitors and antihyperglycemic agents.
    Journal of medicinal chemistry, 1992, Nov-27, Volume: 35, Issue:24

    Topics: Aldehyde Reductase; Animals; Blood Glucose; Cattle; Diabetes Mellitus, Experimental; Glyceraldehyde; Hypoglycemic Agents; Indoles; Male; Mice; Mice, Inbred C57BL; Molecular Structure; Rats; Structure-Activity Relationship; Succinimides; Thiazoles; Thiazolidinediones

1992