adn 138 has been researched along with sorbinil in 2 studies
| Studies (adn 138) | Trials (adn 138) | Recent Studies (post-2010) (adn 138) | Studies (sorbinil) | Trials (sorbinil) | Recent Studies (post-2010) (sorbinil) |
|---|---|---|---|---|---|
| 5 | 0 | 0 | 500 | 44 | 43 |
| Protein | Taxonomy | adn 138 (IC50) | sorbinil (IC50) |
|---|---|---|---|
| Aldo-keto reductase family 1 member B10 | Homo sapiens (human) | 5.05 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 0.8698 | |
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | 0.5 | |
| Aldo-keto reductase family 1 member A1 | Homo sapiens (human) | 5.1333 | |
| Aldo-keto reductase family 1 member B1 | Homo sapiens (human) | 1.3166 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 3.04 | |
| Aldo-keto reductase family 1 member B1 | Bos taurus (cattle) | 1.7292 | |
| Aldo-keto reductase family 1 member A1 | Sus scrofa (pig) | 2.95 | |
| Aldo-keto reductase family 1 member A1 | Rattus norvegicus (Norway rat) | 0.8845 | |
| Aldo-keto reductase family 1 member B1 | Sus scrofa (pig) | 1.1 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 1.1 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dietrich, A; Harrison, MC; Hohman, TC; McCaleb, M; Millen, J; Sredy, J; Sullivan, D; Woolson, SA; Wrobel, J | 1 |
| Fujimori, S; Hirata, Y; Okada, K | 1 |
2 other study(ies) available for adn 138 and sorbinil
| Article | Year |
|---|---|
Novel spirosuccinimides with incorporated isoindolone and benzisothiazole 1,1-dioxide moieties as aldose reductase inhibitors and antihyperglycemic agents.
Topics: Aldehyde Reductase; Animals; Blood Glucose; Cattle; Diabetes Mellitus, Experimental; Glyceraldehyde; Hypoglycemic Agents; Indoles; Male; Mice; Mice, Inbred C57BL; Molecular Structure; Rats; Structure-Activity Relationship; Succinimides; Thiazoles; Thiazolidinediones | 1992 |
Effect of a new aldose reductase inhibitor, 8'-chloro-2',3'-dihydrospiro [pyrrolidine-3,6'(5'H)-pyrrolo[1,2,3-de] [1,4]benzoxazine]-2,5,5'- trione (ADN-138), on delayed motor nerve conduction velocity in streptozotocin-diabetic rats.
Topics: Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Glucose; Imidazoles; Imidazolidines; Inositol; Male; Motor Neurons; Neural Conduction; Oxazines; Pyrroles; Rats; Rats, Inbred Strains; Sciatic Nerve; Sodium-Potassium-Exchanging ATPase; Sorbitol; Sugar Alcohol Dehydrogenases | 1988 |