Page last updated: 2024-08-17

adenosine monophosphate and organophosphonates

adenosine monophosphate has been researched along with organophosphonates in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199015 (46.88)18.7374
1990's2 (6.25)18.2507
2000's7 (21.88)29.6817
2010's5 (15.63)24.3611
2020's3 (9.38)2.80

Authors

AuthorsStudies
Benkovic, PA; Benkovic, SJ; Lazarus, RA1
Brand, LM; Lowenstein, JM1
Dixon, HB; Southgate, CC1
Balzarini, J; De Clercq, E1
Lee, RW; Thompson, SN1
Aoe, H; Pogell, BM; Sarngadharan, MG; Taketa, K; Watanabe, A1
Danenberg, PV; Montgomery, KA; Santi, DV1
Horecker, BL; Nakashima, K1
Hampton, A; Paul, B; Sasaki, T1
Jordan, F1
Allewell, NM; Carlson, WD; Lee, B; Mitsui, Y; Richards, FM; Wyckoff, HW1
Hampton, A; Harper, PJ; Perini, F1
Chappell, JB; Johnson, RN1
Feldmann, K; Gaugler, BJ; Helmreich, EJ; Winkler, H1
Fischer, EH; Hullar, TL; Pocker, A; Vidgoff, JM1
Curthoys, NP; Rabinowitz, JC1
Balzarini, J; De Clercq, E; Hatse, S; Naesens, L1
Folkers, G; Pautsch, A; Perozzo, R; Pilger, B; Prota, A; Scapozza, L; Schelling, P; Schulz, GE; Vogt, J1
Antoniou, T; Park-Wyllie, LY; Tseng, AL1
Dang, Q; Erion, MD; Jiang, T; Kasibhatla, SR; Lipscomb, WN; Potter, SC; Reddy, KR; Reddy, MR; van Poelje, PD1
Kiss, Z; Le Du, MH; Llinas, P; Ménez, A; Millán, JL; Stigbrand, T; Stura, EA1
Daub, E; Honek, JF; Sampson, PB; Vaughan, MD1
Chen, L; Hedstrom, L; Jayaram, HN; Olesiak, M; Pankiewicz, KW; Patterson, SE; Rejman, D; Wilson, D1
Brown, BS; Dang, Q; Erion, MD; Liu, Y; Reddy, MR; Robinson, ED; Rydzewski, RM; van Poelje, PD1
Dang, Q; Dare, J; Erion, MD; Gibson, T; Kasibhatla, SR; Liu, Y; Potter, SC; Reddy, KR; Scarlato, GR; Taplin, F; van Poelje, PD; Xiao, W1
Balasubramanian, R; Jacobson, KA; Joshi, BV; Kumar, TS; Liang, BT; Yang, T; Zhou, SY1
Jadhav, A; Lea, WA; Maloney, DJ; McCoy, ES; Mott, BT; Simeonov, A; Zylka, MJ1
Amiable, C; Kaminski, PA; Labesse, G; Padilla, A; Pochet, S1
Cordonier, EL; Dussault, PH; Sittiwong, W; Zempleni, J1
Cao, W; Fu, Y; Guan, H; Kang, Z; Kong, X; Li, J; Tu, Y; Wang, Q; Wang, Y; Yin, J1
Beavers, CJ; Dobesh, PP; Effoe, SA1
Sigel, A; Sigel, H; Sigel, RKO1

Reviews

2 review(s) available for adenosine monophosphate and organophosphonates

ArticleYear
Tenofovir: a nucleotide analog for the management of human immunodeficiency virus infection.
    Pharmacotherapy, 2003, Volume: 23, Issue:1

    Topics: Adenine; Adenosine Monophosphate; Anti-HIV Agents; Biological Availability; HIV Infections; HIV-1; Humans; Inhibitory Concentration 50; Organophosphonates; Organophosphorus Compounds; Randomized Controlled Trials as Topic; Tenofovir; Treatment Outcome; Viral Load

2003
Coordination Chemistry of Nucleotides and Antivirally Active Acyclic Nucleoside Phosphonates, including Mechanistic Considerations.
    Molecules (Basel, Switzerland), 2022, Apr-19, Volume: 27, Issue:9

    Topics: Adenine; Adenosine Monophosphate; Adenosine Triphosphate; Antiviral Agents; Chelating Agents; Ethers; Ions; Metals; Nucleosides; Nucleotides; Organophosphonates; Oxygen; Phosphates; Sugars

2022

Other Studies

30 other study(ies) available for adenosine monophosphate and organophosphonates

ArticleYear
The synthesis and properties in enzymic reactions of substrate analogs containing the methylphosphonyl group.
    Archives of biochemistry and biophysics, 1979, Oct-01, Volume: 197, Issue:1

    Topics: Acetate Kinase; Adenosine Monophosphate; Adenosine Triphosphate; Organophosphonates; Phosphoenolpyruvate; Phosphotransferases; Pyruvate Kinase; Substrate Specificity

1979
Inhibition of adenylosuccinase by adenylophosphonopropionate and related compounds.
    Biochemistry, 1978, Apr-18, Volume: 17, Issue:8

    Topics: Adenosine Monophosphate; Animals; Binding Sites; Binding, Competitive; Kinetics; Lyases; Male; Muscles; Organophosphonates; Rats; Species Specificity; Substrate Specificity; Succinates

1978
Phosphonate analogues of aminoacyl adenylates.
    The Biochemical journal, 1978, Nov-01, Volume: 175, Issue:2

    Topics: Adenosine Monophosphate; Binding Sites; Drug Stability; Glycine; Kinetics; Organophosphonates; Valine; Valine-tRNA Ligase

1978
Conversion of acyclic nucleoside phosphonates to their diphosphate derivatives by 5-phosphoribosyl-1-pyrophosphate (PRPP) synthetase.
    Advances in experimental medicine and biology, 1991, Volume: 309A

    Topics: Adenine; Adenosine Monophosphate; Adenosine Triphosphate; Biotransformation; Escherichia coli; Kinetics; Organophosphonates; Ribose-Phosphate Pyrophosphokinase; Substrate Specificity

1991
31P NMR studies on adenylates and other phosphorus metabolites in the schistosome vector Biomphalaria glabrata.
    The Journal of parasitology, 1985, Volume: 71, Issue:5

    Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Biomphalaria; Magnetic Resonance Spectroscopy; Organophosphonates; Phosphates; Phosphorylation; Schistosoma mansoni

1985
Reversible inactivation of rabbit liver fructose 1,6-diphosphatase by adenosine triphosphate and adenosine diphosphate.
    The Journal of biological chemistry, 1971, Sep-25, Volume: 246, Issue:18

    Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Binding Sites; Catalysis; Cattle; Dicarboxylic Acids; Edetic Acid; Fructose-Bisphosphatase; Fructosephosphates; Glycerophosphates; Glycolysis; Glycosides; Hydrogen-Ion Concentration; Kinetics; Liver; Magnesium; Nucleosides; Nucleotides; Organophosphonates; Phosphates; Phosphoric Acids; Rabbits; Serum Albumin, Bovine; Tricarboxylic Acids

1971
Phenylalanyl transfer ribonucleic acid synthetase from Escherichia coli. Analysis of the adenosine triphosphate binding site.
    Biochemistry, 1971, Dec-07, Volume: 10, Issue:25

    Topics: Acylation; Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Alcohols; Amino Acyl-tRNA Synthetases; Binding Sites; Cyclohexanes; Deoxyadenosines; Diphosphates; Escherichia coli; Organophosphonates; Phosphoric Acids; Phosphorus Isotopes; Protein Binding; Purines; Structure-Activity Relationship; Thermodynamics

1971
Modification of the catalytic properties of rabbit liver fructose diphosphatase by a particulate fraction from liver.
    Archives of biochemistry and biophysics, 1971, Volume: 146, Issue:1

    Topics: Adenosine Monophosphate; Adenosine Triphosphate; Ammonium Sulfate; Animals; Carrier Proteins; Catalysis; Chemical Precipitation; Chromatography, Ion Exchange; Coenzyme A; Cysteine; Disulfides; Dithiothreitol; Enzyme Activation; Filtration; Fructose-Bisphosphatase; Fructosephosphates; Homocystine; Hydrogen-Ion Concentration; Kinetics; Liver; Magnesium; Organophosphonates; Phenols; Phosphoric Monoester Hydrolases; Rabbits

1971
Synthesis of 6'-cyano-6'-deoxyhomoadenosine-6'-phosphonic acid and its phosphoryl and pyrophosphoryl anhydrides and studies of their interactions with adenine nucleotide utilizing enzymes.
    Journal of the American Chemical Society, 1973, Jun-27, Volume: 95, Issue:13

    Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aminohydrolases; Anhydrides; Animals; Binding Sites; Chemical Phenomena; Chemistry; Diphosphates; Enzyme Repression; Muscles; Nucleotidases; Organophosphonates; Phosphotransferases; Rabbits; Swine

1973
The electronic structure of and conformational energy barrier to rotation a round the C-N glycosidic linkage in adenosine-3',5'-cyclicmonophosphate (cyclic AMP) and its phosphonate analog.
    Journal of theoretical biology, 1973, Sep-14, Volume: 41, Issue:1

    Topics: Adenosine Monophosphate; Adenosine Triphosphate; Cyclic AMP; Energy Transfer; Molecular Conformation; Organophosphonates; Quantum Theory

1973
Protein structure, ribonuclease-S and nucleotide interactions.
    Cold Spring Harbor symposia on quantitative biology, 1972, Volume: 36

    Topics: Adenine Nucleotides; Adenosine Monophosphate; Amino Acid Sequence; Binding Sites; Cytosine Nucleotides; Macromolecular Substances; Models, Structural; Muramidase; Myoglobin; Organophosphonates; Peptides; Protein Conformation; Ribonucleases; Ribonucleotides; Solvents; Thermodynamics; Uracil Nucleotides

1972
Synthesis of homoadenosine-6'-phosphonic acid and studies of its substrate and inhibitor properties with adenosine monophosphate utilizing enzymes.
    Biochemistry, 1973, Apr-24, Volume: 12, Issue:9

    Topics: Acetals; Adenine Nucleotides; Adenosine Monophosphate; Aminohydrolases; Animals; Binding, Competitive; Chromatography, Paper; Deamination; Deoxyribonucleotides; Electrophoresis, Paper; Kinetics; Magnetic Resonance Spectroscopy; Muscles; Nucleotidases; Organophosphonates; Phosphotransferases; Protons; Rabbits; Snakes; Stereoisomerism; Swine; Venoms

1973
The inhibition of mitochondrial dicarboxylate transport by inorganic phosphate, some phosphate esters and some phosphonate compounds.
    The Biochemical journal, 1974, Volume: 138, Issue:2

    Topics: Adenosine Monophosphate; Benzoates; Binding Sites; Binding, Competitive; Biological Transport; Esters; Ethylmaleimide; Fructosephosphates; Glucosephosphates; Glycerophosphates; In Vitro Techniques; Kinetics; Mitochondria; Mitochondrial Swelling; Nitrophenols; Organophosphonates; Organophosphorus Compounds; Phosphates; Phosphoric Acids; Succinate Dehydrogenase; Succinates

1974
Conformational transitions in glycogen phosphorylase reported by covalently bound pyridoxamine derivatives.
    Biochemistry, 1974, May-07, Volume: 13, Issue:10

    Topics: Adenosine Monophosphate; Animals; Binding Sites; Drug Stability; Glycogen; Hydrogen-Ion Concentration; Kinetics; Macromolecular Substances; Models, Chemical; Muscles; Organophosphonates; Organophosphorus Compounds; Oxidation-Reduction; Phosphorylases; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Pyridoxamine; Rabbits; Scattering, Radiation; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Structure-Activity Relationship

1974
Interaction of muscle glycogen phosphorylase with pyridoxal 5'-methylenephosphonate.
    Biochemical and biophysical research communications, 1974, Apr-23, Volume: 57, Issue:4

    Topics: Adenosine Monophosphate; Animals; Binding Sites; Crystallization; Hydrogen-Ion Concentration; Kinetics; Muscles; Organophosphonates; Organophosphorus Compounds; Phosphorylases; Protein Binding; Protein Conformation; Pyridoxal; Pyridoxal Phosphate; Rabbits; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Ultracentrifugation

1974
Formyltetrahydrofolate synthetase. Binding of adenosine triphosphate and related ligands determined by partition equilibrium.
    The Journal of biological chemistry, 1971, Nov-25, Volume: 246, Issue:22

    Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Binding Sites; Carbon Isotopes; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, Gel; Clostridium; Crystallization; Dextrans; Dialysis; Folic Acid; Formates; Glycols; Kinetics; Ligases; Magnesium; Mathematics; Methods; Organophosphonates; Oxidation-Reduction; Phosphates; Polyethylenes; Protein Binding; Thermodynamics; Tritium

1971
Selection and characterisation of murine leukaemia L1210 cells with high-level resistance to the cytostatic activity of the acyclic nucleoside phosphonate 9-(2-phosphonylmethoxyethyl) adenine (PMEA).
    Biochimica et biophysica acta, 1998, Mar-12, Volume: 1402, Issue:1

    Topics: Adenine; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antineoplastic Agents; Biological Transport; Biotransformation; Cell Survival; Cyclic AMP; Drug Resistance, Neoplasm; Guanine; Kinetics; Leukemia L1210; Mice; Organophosphonates; Organophosphorus Compounds; Purine Nucleotides; Structure-Activity Relationship; Tumor Cells, Cultured

1998
Nucleoside binding site of herpes simplex type 1 thymidine kinase analyzed by X-ray crystallography.
    Proteins, 2000, Dec-01, Volume: 41, Issue:4

    Topics: Adenine; Adenosine; Adenosine Monophosphate; Amino Acid Substitution; Antiviral Agents; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Enzyme Inhibitors; Herpesvirus 1, Human; Mutation; Nucleosides; Organophosphonates; Prodrugs; Protein Structure, Tertiary; Stereoisomerism; Substrate Specificity; Thymidine; Thymidine Kinase; Viral Proteins; Water

2000
MB06322 (CS-917): A potent and selective inhibitor of fructose 1,6-bisphosphatase for controlling gluconeogenesis in type 2 diabetes.
    Proceedings of the National Academy of Sciences of the United States of America, 2005, May-31, Volume: 102, Issue:22

    Topics: Adenosine Monophosphate; Alanine; Analysis of Variance; Animals; Carbon Radioisotopes; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Design; Fructose-Bisphosphatase; Gluconeogenesis; Humans; Liver; Male; Molecular Mimicry; Organophosphonates; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Rats, Zucker; Spectrophotometry; Thiazoles

2005
Structural studies of human placental alkaline phosphatase in complex with functional ligands.
    Journal of molecular biology, 2005, Jul-15, Volume: 350, Issue:3

    Topics: Adenosine Monophosphate; Alkaline Phosphatase; Binding Sites; Catalytic Domain; Cell Proliferation; Crystallography, X-Ray; Down-Regulation; Fibroblasts; Humans; Hydrolysis; Ligands; Models, Molecular; Molecular Conformation; Nitrophenols; Organophosphonates; Phenylalanine; Placenta; Protein Conformation; Protein Isoforms; Protein Structure, Tertiary

2005
Investigation of bioisosteric effects on the interaction of substrates/ inhibitors with the methionyl-tRNA synthetase from Escherichia coli.
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2005, Volume: 1, Issue:3

    Topics: Adenosine; Adenosine Monophosphate; Anti-Bacterial Agents; Enzyme Inhibitors; Escherichia coli; Homocysteine; Methionine; Methionine-tRNA Ligase; Organophosphonates; Phosphinic Acids; Protein Conformation; Stereoisomerism; Substrate Specificity

2005
Novel methylenephosphophosphonate analogues of mycophenolic adenine dinucleotide. Inhibition of inosine monophosphate dehydrogenase.
    Journal of medicinal chemistry, 2006, Aug-10, Volume: 49, Issue:16

    Topics: Adenine Nucleotides; Adenosine Monophosphate; Humans; IMP Dehydrogenase; Mycophenolic Acid; Organophosphonates; Structure-Activity Relationship

2006
Fructose-1,6-bisphosphatase inhibitors. 1. Purine phosphonic acids as novel AMP mimics.
    Journal of medicinal chemistry, 2009, May-14, Volume: 52, Issue:9

    Topics: Adenosine Monophosphate; Administration, Oral; Animals; Biological Availability; Biomimetics; Diabetes Mellitus, Type 2; Drug Design; Enzyme Inhibitors; Fructose-Bisphosphatase; Glucose; Humans; Inhibitory Concentration 50; Liver; Organophosphonates; Purines; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Substrate Specificity

2009
Fructose-1,6-bisphosphatase Inhibitors. 2. Design, synthesis, and structure-activity relationship of a series of phosphonic acid containing benzimidazoles that function as 5'-adenosinemonophosphate (AMP) mimics.
    Journal of medicinal chemistry, 2010, Jan-14, Volume: 53, Issue:1

    Topics: Adenosine Monophosphate; Animals; Benzimidazoles; Diabetes Mellitus, Type 2; Disease Models, Animal; Drug Design; Enzyme Inhibitors; Fructose-Bisphosphatase; Humans; Liver; Molecular Structure; Organophosphonates; Rats; Rats, Zucker; Stereoisomerism; Structure-Activity Relationship

2010
Structure-activity relationship of (N)-Methanocarba phosphonate analogues of 5'-AMP as cardioprotective agents acting through a cardiac P2X receptor.
    Journal of medicinal chemistry, 2010, Mar-25, Volume: 53, Issue:6

    Topics: Adenosine Monophosphate; Animals; Calcium; Cardiotonic Agents; Cell Line, Tumor; Echocardiography; Female; Heart; Humans; Infusion Pumps; Intracellular Space; Male; Mice; Models, Chemical; Molecular Structure; Myocardium; Organophosphonates; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2Y1; Structure-Activity Relationship

2010
High-throughput screen identifies cyclic nucleotide analogs that inhibit prostatic acid phosphatase.
    Journal of biomolecular screening, 2013, Volume: 18, Issue:4

    Topics: Acid Phosphatase; Adenosine Monophosphate; Animals; Cattle; Computer Systems; Dose-Response Relationship, Drug; Enzyme Inhibitors; High-Throughput Screening Assays; Humans; Hydrolysis; Inhibitory Concentration 50; Mice; Nucleotidases; Nucleotides, Cyclic; Organophosphonates; Protein Tyrosine Phosphatases; Reproducibility of Results; Small Molecule Libraries

2013
Structure of the oncoprotein Rcl bound to three nucleotide analogues.
    Acta crystallographica. Section D, Biological crystallography, 2013, Volume: 69, Issue:Pt 2

    Topics: Acenaphthenes; Adenosine Monophosphate; Amino Acid Sequence; Amino Acid Substitution; Animals; Crystallization; Ligands; Molecular Sequence Data; N-Glycosyl Hydrolases; Nucleotides; Oncogene Proteins; Organophosphonates; Phosphorylation; Protein Binding; Protein Interaction Mapping; Rats; Ribonucleotides; Thionucleotides; Thymidine; X-Ray Diffraction

2013
β-Keto and β-hydroxyphosphonate analogs of biotin-5'-AMP are inhibitors of holocarboxylase synthetase.
    Bioorganic & medicinal chemistry letters, 2014, Dec-15, Volume: 24, Issue:24

    Topics: Adenosine Monophosphate; Biotin; Carbon-Nitrogen Ligases; Humans; Ketones; Kinetics; Organophosphonates; Protein Binding

2014
Defect-Assisted Loading and Docking Conformations of Pharmaceuticals in Metal-Organic Frameworks.
    Angewandte Chemie (International ed. in English), 2021, 03-29, Volume: 60, Issue:14

    Topics: Adenosine Monophosphate; Drug Compounding; Drug Liberation; Metal-Organic Frameworks; Molecular Conformation; Molecular Docking Simulation; Nanocapsules; Organometallic Compounds; Organophosphonates; Phosphates; Phthalic Acids; Porosity; Surface Properties

2021
Selatogrel: A Novel Subcutaneous P2Y12 Inhibitor.
    Journal of cardiovascular pharmacology, 2022, 02-01, Volume: 79, Issue:2

    Topics: Acute Coronary Syndrome; Adenosine Monophosphate; Humans; Organophosphonates; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Pyrimidines

2022