adenosine monophosphate has been researched along with leucine in 52 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (63.46) | 18.7374 |
| 1990's | 3 (5.77) | 18.2507 |
| 2000's | 3 (5.77) | 29.6817 |
| 2010's | 4 (7.69) | 24.3611 |
| 2020's | 9 (17.31) | 2.80 |
| Authors | Studies |
|---|---|
| Fields, JH; Hochachka, PW; Storey, KB | 1 |
| Kleinkauf, H; Vater, J | 1 |
| De Robertis, EM; Judewicz, ND; Torres, HN | 2 |
| Blanchard, P; Lawrence, DA; Lawrence, F; Robert-Gero, M | 1 |
| Clarke, CM; Knowles, JR | 1 |
| Ciaramitaro, D; Eisenstein, D; Huxtable, R | 1 |
| Atkinson, DE; Sedo, RJ; Swedes, JS | 1 |
| Molnar, J | 1 |
| Abramowitz, A; Bromwell, K; DeLarco, J; Gurogg, G; Nakagawa, S | 1 |
| Lawrence, F; Robert-Gero, M; Vigier, P | 1 |
| Fukui, T; Okajima, T; Tanizawa, K; Yoneya, T | 1 |
| Fukui, T; Okajima, T; Tagaya, M; Tanizawa, K; Yoneya, T | 1 |
| Cramer, F; Englisch, S; Englisch, U; von der Haar, F | 1 |
| Bryce, GF | 1 |
| Brown, A; Culver, JM; Fisher, HF | 1 |
| Foldes, A; Meek, JL | 1 |
| Stent, GS; Yegian, CD | 1 |
| Morgan, K; Phang, JM; Weiss, IW | 1 |
| Aboud, M; Burger, M | 1 |
| Fast, D; Heisler, S; Tenenhouse, A | 1 |
| Axén, R; Vretblad, P | 1 |
| Prasad, KN; Waymire, JC; Weiner, N | 1 |
| Poliakova, TD; Savenko, VA | 1 |
| Netrawali, MS; Pradhan, DS; Sreenivasan, A; Subba Rao, MN | 1 |
| De Schepper, PJ; Debeer, LJ; Mannaerts, G | 1 |
| Adelman, RC; Stein, GS; Wang, PL | 1 |
| Cerná, J; Gottikh, BP; Krayevsky, AA; Rychlík, I | 1 |
| Hallman, M | 1 |
| Kondo, M | 1 |
| Laland, SG; Saxholm, H; Zimmer, TL | 1 |
| Danon, D; Zehavi-Willner, T | 1 |
| Bomboy, JD; Salmon, WD; Sullivan, JN | 1 |
| Dreiling, CE; Starich, GH | 1 |
| Gunasekera, D; Kemp, RG; Li, Y; Rivera, D; Ru, W | 1 |
| Ayabe, T; Hamada, M; Maruyama, H; Onitsuka, T; Park, SK; Sumida, M; Takenaka, H; Takenaka, O | 1 |
| KUBY, SA; OLSON, OE | 1 |
| Barta, A; Dorner, S; Schmid, W | 1 |
| Doi, M; Mochizuki, S; Nakayama, M; Sugahara, K; Yamaoka, I; Yoshizawa, F | 1 |
| Damre, MV; Gangwal, RP; Sangamwar, AT; Singh, S; Soumya, N; Tandan, H | 1 |
| Djukovic, D; Gu, H; O'Keefe, GE; Parent, BA; Raftery, D; Seaton, M; Sood, RF | 1 |
| Kosono, S; Kuzuyama, T; Matsushita, H; Nishiyama, M; Tomita, T; Yoshida, A; Yoshida, M | 1 |
| Hu, Y; Hurst, B; Ma, C; Szeto, T; Tarbet, B; Wang, J | 1 |
| Dolgin, E | 1 |
| Allerton, C; Anderson, AS; Anson, BJ; Arenson, D; Aschenbrenner, L; Bakowski, MA; Beutler, N; Binder, J; Boras, B; Chatterjee, AK; Chen, E; Eng, H; Frieman, MB; García-Sastre, A; Hammond, H; Hammond, J; Haupt, RE; Hoffman, R; Jones, RM; Kadar, EP; Kania, R; Kimoto, E; Kirkpatrick, MG; Lanyon, L; Lendy, EK; Lillis, JR; Logue, J; Luthra, SA; Ma, C; Mason, SW; McGrath, ME; Mesecar, AD; Noell, S; O' Brien, MN; O'Connor, R; Obach, RS; Ogilvie, K; Owen, D; Pettersson, M; Reese, MR; Rogers, TF; Rosales, R; Rossulek, MI; Sathish, JG; Shirai, N; Steppan, C; Ticehurst, M; Updyke, LW; Wang, J; Weston, S; White, KM; Zhu, Y | 1 |
| Del Rio, C; Gandhi, RT; Malani, PN | 1 |
| Misra, A; Singh, A; Singh, AK; Singh, R | 1 |
| Kozlov, M | 1 |
| André, E; Chiu, W; De Jonghe, S; Jochmans, D; Leyssen, P; Maes, P; Neyts, J; Raymenants, J; Slechten, B; Vangeel, L | 1 |
| Ledford, H | 1 |
1 trial(s) available for adenosine monophosphate and leucine
| Article | Year |
|---|---|
An updated practical guideline on use of molnupiravir and comparison with agents having emergency use authorization for treatment of COVID-19.
Topics: Adenosine Monophosphate; Aged; Alanine; Animals; Antiviral Agents; COVID-19; COVID-19 Drug Treatment; COVID-19 Vaccines; Cytidine; Double-Blind Method; Drug Approval; Drug Combinations; Female; Hospitalization; Humans; Hydroxylamines; Lactams; Leucine; Male; Middle Aged; Nitriles; Proline; Ritonavir; SARS-CoV-2; Severity of Illness Index; Treatment Outcome | 2022 |
51 other study(ies) available for adenosine monophosphate and leucine
| Article | Year |
|---|---|
Purification and properties of glutamate dehydrogenase from the mantle muscle of the squid, Loligo pealeii. Role of the enzyme in energy production from amino acids.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Amino Acids; Animals; Decapodiformes; Energy Metabolism; Enzyme Activation; Glutamate Dehydrogenase; Guanosine Triphosphate; Hydrogen-Ion Concentration; Kinetics; Leucine; Molecular Weight; Muscles | 1978 |
Substrate specificity of the amino acyl adenylate activation sites of gramicidin S-synthetase (GSS).
Topics: Acetylation; Adenosine Monophosphate; Amino Acid Isomerases; Amino Acids; Bacillus; Binding Sites; Esters; Gramicidin; Leucine; Lysine; Multienzyme Complexes; Ornithine; Peptide Synthases; Phenylalanine; Proline; Stereoisomerism; Valine | 1975 |
Regulation of uracil uptake in Escherichia coli by adenosine 3',5'-monophosphate.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Biological Transport, Active; Cell Division; Cyclic AMP; Escherichia coli; Galactosidases; Kinetics; Leucine; Protein Biosynthesis; Uracil | 1976 |
Further studies of the action of methionyl adenylate on chick embryo fibroblasts.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine Monophosphate; Animals; Chick Embryo; DNA; Fibroblasts; Leucine; Methionine; Methionine-tRNA Ligase; Phosphoric Diester Hydrolases; Protein Biosynthesis; RNA; Thymidine; Uridine | 1977 |
Affinity chromatography of aminoacyl-transfer ribonucleic acid synthetases. Small organic ligands.
Topics: Adenosine Monophosphate; Amino Acyl-tRNA Synthetases; Chromatography, Affinity; Leucine; Ligands; Sepharose | 1977 |
The effect of a pyrrolizidine alkaloid, monocrotaline, and a pyrrole, dehydroretronecine, on the biochemical functions of the pulmonary endothelium.
Topics: Adenosine Monophosphate; Animals; Blood Pressure; Endothelium; Heart; In Vitro Techniques; Leucine; Lung; Male; Monocrotaline; Norepinephrine; Organ Size; Plants, Toxic; Pyrroles; Pyrrolizidine Alkaloids; Rats; Senecio; Serotonin; Time Factors; Tissue Distribution | 1978 |
Relation of growth and protein synthesis to the adenylate energy charge in an adenine-requiring mutant of Escherichia coli.
Topics: Adenine; Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Bacterial Proteins; Cell Division; Escherichia coli; Glucose; Leucine; Mutation; Protein Biosynthesis | 1975 |
A proposed pathway of plasma glycoprotein synthesis.
Topics: Acetylglucosamine; Adenosine Monophosphate; Animals; Biological Transport; Endoplasmic Reticulum; Glycopeptides; Glycoproteins; Golgi Apparatus; Leucine; Lipids; Liver; Membranes; Microsomes, Liver; Protein Binding; Puromycin; Rabbits; Rats; Ribosomes; RNA, Transfer; Uridine Diphosphate Sugars | 1975 |
Polyadenylic acid-containing RNA from rat brain synaptosomes.
Topics: Adenosine; Adenosine Monophosphate; Animals; Brain; Cell Nucleus; Centrifugation, Density Gradient; Chromatography; Electrophoresis, Polyacrylamide Gel; Leucine; Membranes; Mitochondria; Polyribosomes; Rats; RNA; Synaptosomes; Templates, Genetic; Tritium; Uridine | 1975 |
Reversible inhibition by methioninyl adenylate of protein synthesis and growth in chick enbyo fibroblasts.
Topics: Adenosine Monophosphate; Amino Acyl-tRNA Synthetases; Animals; Cell Survival; Chick Embryo; Clone Cells; Fibroblasts; Kinetics; Leucine; Methionine; Protein Biosynthesis; Time Factors | 1975 |
Role of leucine 66 in the asymmetric recognition of substrates in chicken muscle adenylate kinase.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Adenylate Kinase; Amino Acid Sequence; Animals; Base Sequence; Chickens; Circular Dichroism; Electrophoresis, Polyacrylamide Gel; Fluorescence Polarization; Kinetics; Leucine; Molecular Sequence Data; Muscles; Mutagenesis, Site-Directed; Protein Conformation; Substrate Specificity | 1991 |
The role of Leu-190 in the function and stability of adenylate kinase.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Adenylate Kinase; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Chickens; Circular Dichroism; DNA Mutational Analysis; In Vitro Techniques; Kinetics; Leucine; Molecular Sequence Data; Solubility; Spectrometry, Fluorescence; Structure-Activity Relationship | 1990 |
The proofreading of hydroxy analogues of leucine and isoleucine by leucyl-tRNA synthetases from E. coli and yeast.
Topics: Adenosine Monophosphate; Amino Acyl-tRNA Synthetases; Escherichia coli; Homocysteine; Hydrolysis; Isoleucine; Lactones; Leucine; Leucine-tRNA Ligase; Protein Biosynthesis; RNA, Transfer, Amino Acyl; Saccharomyces cerevisiae | 1986 |
Studies on the enzymes involved in the biosynthesis of cyclo-tris (N-2,3-dihydroxybenzoyl-L-seryl) in Escherichia coli: kinetic properties of the L-serine-activating enzyme.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Alanine; Anti-Bacterial Agents; Drug Stability; Enzyme Induction; Escherichia coli; Ethylmaleimide; Glycine; Gramicidin; Histidine; Hydrogen-Ion Concentration; Kinetics; Leucine; Lysine; Phosphates; Phosphorus Radioisotopes; Proline; Serine; Threonine; Time Factors; Tritium; Tyrosine | 1973 |
Mechanism of inactivation of L-glutamate dehydrogenase by pyridoxal and pyridoxal phosphate.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Animals; Binding Sites; Borohydrides; Cattle; Chromatography, Gel; Glutamate Dehydrogenase; Glutamates; Ketoglutaric Acids; Kinetics; Leucine; Liver; Mathematics; NADP; Oxidation-Reduction; Protein Binding; Pyridoxal; Pyridoxal Phosphate; Spectrophotometry, Ultraviolet | 1973 |
Occurrence and localization of brain phenolsulphotransferase.
Topics: Adenosine Monophosphate; Adult; Animals; Brain; Carbon Radioisotopes; Cerebellum; Cerebral Cortex; Chickens; Choroid Plexus; Cold Temperature; Corpus Striatum; Cycloheximide; Freezing; Guinea Pigs; Haplorhini; Hippocampus; Humans; Hypothalamus; Leucine; Male; Medulla Oblongata; Mesencephalon; Mice; Neuroglia; Organ Specificity; Phenols; Pineal Gland; Pituitary Gland; Rabbits; Rana catesbeiana; Rats; Sulfur Radioisotopes; Sulfuric Acids; Sulfurtransferases; Time Factors | 1974 |
An unusual condition of leucine transfer RNA appearing during leucine starvation of Escherichia coli.
Topics: Acylation; Adenosine Monophosphate; Amino Acids; Amino Acyl-tRNA Synthetases; Diphosphates; Escherichia coli; Leucine; Methods; Oxidation-Reduction; Periodic Acid; Phenotype; RNA, Transfer; Transfer RNA Aminoacylation; Tritium | 1969 |
Cyclic adenosine monophosphate-stimulated transport of amino acids in kidney cortex.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Amino Acids; Aminoisobutyric Acids; Animals; Arginine; Biological Transport, Active; Butyrates; Carbon Isotopes; Cyclic AMP; Cycloheximide; Glycine; Insulin; Kidney; Kinetics; Leucine; Lysine; Male; Ouabain; Parathyroid Hormone; Proline; Puromycin; Rats; Sodium; Vasopressins | 1972 |
Adenosine triphosphate and catabolite repression of -galactosidase in escherichia coli.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Carbon Isotopes; Cyclic AMP; Cytosine Nucleotides; Drug Antagonism; Enzyme Repression; Escherichia coli; Galactosidases; Glycerol; Guanosine Triphosphate; Leucine; Spheroplasts; Uracil Nucleotides | 1971 |
Role of Ca 2+ and cyclic AMP in protein secretion from rat exocrine pancreas.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Butyrates; Calcium; Carbachol; Cyclic AMP; Drug Synergism; Female; In Vitro Techniques; Leucine; Manganese; Pancreas; Protein Biosynthesis; Proteins; Rats; Theophylline; Time Factors; Tritium | 1972 |
The use of isocyanides for the immobilization of biological molecules.
Topics: Acrylamides; Adenosine Monophosphate; Biotin; Chromatography, Gel; Chymotrypsin; Cyanides; Esters; Humans; Hydrogen-Ion Concentration; Leucine; Methods; Molecular Weight; NAD; Penicillanic Acid; Penicillin G; Phenylalanine; Protein Binding; RNA; Serum Albumin; Temperature; Tyrosine | 1973 |
Control of uracil transport by cyclic AMP in E. coli.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Biological Transport; Carbon Radioisotopes; Cell Division; Cyclic AMP; Enzyme Induction; Escherichia coli; Galactosidases; Glucose; Kinetics; Leucine; Malates; Mutation; Rifampin; Solubility; Succinates; Time Factors; Tritium; Uracil | 1974 |
A further study on the morphology and biochemistry of x-ray and dibutyryl cyclic AMP-induced differentiated neuroblastoma cells in culture.
Topics: Adenosine Monophosphate; Animals; Axons; Butyrates; Cell Transformation, Neoplastic; Cells, Cultured; Cyclic AMP; Cycloheximide; Dactinomycin; DNA, Neoplasm; Leucine; Mice; Mitosis; Neoplasm Proteins; Neuroblastoma; Radiation Effects; RNA, Neoplasm; Thymidine; Tritium; Tyrosine 3-Monooxygenase; Uridine | 1972 |
[An enzymohistochemical study of the liver and kidneys in chronic alcoholic intoxication].
Topics: Acid Phosphatase; Adenosine Monophosphate; Adenosine Triphosphatases; Alcohol Oxidoreductases; Alcoholic Intoxication; Alkaline Phosphatase; Aminopeptidases; Animals; Dihydrolipoamide Dehydrogenase; Esterases; Glycerolphosphate Dehydrogenase; Histocytochemistry; Humans; Isocitrate Dehydrogenase; Kidney; Kidney Tubules; L-Lactate Dehydrogenase; Leucine; Liver; Malate Dehydrogenase; Male; NAD; NADP; Oxidoreductases; Phosphoric Monoester Hydrolases; Rats; Succinate Dehydrogenase | 1972 |
Changes at transcriptional level in the rat liver following whole-body x-irradiation.
Topics: Adenosine Monophosphate; Animals; Carbon Radioisotopes; Chromatin; Chromosomes; DNA; Electrophoresis, Polyacrylamide Gel; Isotope Labeling; Leucine; Liver; Male; Molecular Weight; Protein Biosynthesis; Radiation Effects; Rats; RNA; Templates, Genetic; Time Factors; Transcription, Genetic; Tritium | 1974 |
Effects of octanoate and oleate on energy metabolism in the perfused rat liver.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Caprylates; Citric Acid Cycle; Dinitrophenols; Energy Metabolism; Fasting; Fatty Acids; Gluconeogenesis; In Vitro Techniques; Isotope Labeling; Ketone Bodies; Lactates; Leucine; Liver; Male; Oleic Acids; Oligomycins; Oxidation-Reduction; Oxygen Consumption; Perfusion; Protein Biosynthesis; Rats | 1974 |
Age-dependent changes in the structure and function of mammalian chromatin. I. Variations in chromatin template activity.
Topics: Adenosine Monophosphate; Aging; Animals; Carbon Isotopes; Chromatin; Deoxycholic Acid; DNA; DNA-Directed RNA Polymerases; Escherichia coli; Histones; Leucine; Liver; Male; Protein Binding; Proteins; Rats; Ribonucleases; RNA; Submandibular Gland; Templates, Genetic; Trichloroacetic Acid; Tritium | 1973 |
2' (3')-O-N-formylmethionyl)-adenosine-5'-phosphate, a new donor substrate in peptidyl transferase catalyzed reactions.
Topics: Acyltransferases; Adenosine Monophosphate; Calcium; Chloramphenicol; Electrophoresis, Paper; Escherichia coli; Formates; Kinetics; Leucine; Magnesium; Methionine; Peptide Elongation Factors; Peptides; Phenylalanine; Puromycin; Ribosomes; Time Factors; Tritium | 1973 |
Incorporation of 14C-leucine into protein of isolated liver mitochondria with particular reference to energy requirements.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Amino Acids; Animals; Biological Transport; Carbon Radioisotopes; Cell Membrane Permeability; Culture Media; Depression, Chemical; Digitonin; Leucine; Malates; Microsomes, Liver; Mitochondria, Liver; Oligomycins; Oxidative Phosphorylation; Oxygen Consumption; Phosphotransferases; Protein Biosynthesis; Rats; Rotenone; Spectrophotometry | 1973 |
Formation of Eshcerichia coli leucine transfer ribonucleic acid bound enzyme-leucyladenylate complex in vitro.
Topics: Adenine Nucleotides; Adenosine Monophosphate; Amino Acyl-tRNA Synthetases; Chromatography; Escherichia coli; Leucine; RNA, Transfer | 1971 |
The mechanism of the inhibition of gramicidin-S synthesis by D-leucine.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Amino Acid Isomerases; Amino Acids; Aminoacylation; Carbon Isotopes; Esters; Isomerases; Leucine; Multienzyme Complexes; Peptide Chain Elongation, Translational; Peptide Synthases; Peptides; Phosphorus Isotopes; Stereoisomerism; Sulfhydryl Compounds; Tyrothricin | 1972 |
Decay of transfer and total RNA in maturing reticulocytes.
Topics: Adenosine Monophosphate; Amino Acids; Animals; Biological Transport; Blood Proteins; Blood Transfusion; Bone Marrow; Carbon Isotopes; Cell Fractionation; Cell-Free System; Chromatography; Cytosine Nucleotides; Dactinomycin; Depression, Chemical; Electrophoresis; Erythrocyte Aging; Guanine Nucleotides; Leucine; Phenylalanine; Phosphorus Isotopes; Rabbits; Reticulocytes; Ribosomes; RNA; RNA, Ribosomal; RNA, Transfer; Time Factors; Uracil Nucleotides | 1971 |
Stimulation of uridine, leucine, and sulfate incorporation into rat cartilage macromolecules by adenosine 3',5'-monophosphate.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Monophosphate; Animals; Bucladesine; Cartilage; Hypophysectomy; In Vitro Techniques; Leucine; Macromolecular Substances; Male; Nucleotides, Cyclic; Parathyroid Hormone; Rats; Rats, Inbred Strains; Ribs; Stimulation, Chemical; Sulfates; Uridine | 1984 |
Simultaneous inhibition of guinea pig brain 2',3'-cyclic nucleotide 3'-phosphohydrolase and myelin protein synthesis by 2'-adenosine monophosphate.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Adenosine Monophosphate; Animals; Brain; Guinea Pigs; In Vitro Techniques; Leucine; Myelin Proteins; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases | 1980 |
Identification of allosteric sites in rabbit phosphofructo-1-kinase.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Allosteric Site; Animals; Arginine; Enzyme Activators; Enzyme Inhibitors; Escherichia coli; Fructosediphosphates; Geobacillus stearothermophilus; Leucine; Mutagenesis, Site-Directed; Phosphofructokinase-1; Point Mutation; Rabbits | 1999 |
The steady-state kinetics of the enzyme reaction tested by site-directed mutagenesis of hydrophobic residues (Val, Leu, and Cys) in the C-terminal alpha-helix of human adenylate kinase.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Adenylate Kinase; Amino Acid Substitution; Cysteine; Humans; Kinetics; Leucine; Mutagenesis, Site-Directed; Protein Structure, Secondary; Valine | 2000 |
STUDIES ON ADENOSINE TRIPHOSPHATE-ADENOSINE TRIPHOSPHATE TRANSPHOSPHORYLASES. V. CARBOXYL-TERMINAL SEQUENCES OF ADENOSINE TRIPHOSPHATE-CREATINE TRANSPHOSPHORYLASE AND OF ADENOSINE 5'-PHOSPHATE TRANSPHOSPHORYLASE (MYOKINASE).
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Adenylate Kinase; Alanine; Carboxypeptidases; Chromatography; Creatine; Creatine Kinase; Glutamine; Leucine; Lysine; Phosphotransferases; Research; Valine | 1964 |
Activity of 3'-thioAMP derivatives as ribosomal P-site substrates.
Topics: Adenosine Monophosphate; Leucine; Manganese; Models, Chemical; Protein Biosynthesis; Ribosomes; RNA, Transfer, Phe; Thionucleotides | 2005 |
Isoleucine, a blood glucose-lowering amino acid, increases glucose uptake in rat skeletal muscle in the absence of increases in AMP-activated protein kinase activity.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Blood Glucose; Fatty Acids, Nonesterified; Glucose; Glycogen; Hypoglycemic Agents; Insulin; Isoleucine; Leucine; Male; Multienzyme Complexes; Muscle, Skeletal; Osmolar Concentration; Protein Serine-Threonine Kinases; Rats; Rats, Wistar | 2005 |
Leucine-684: A conserved residue of an AMP-acetyl CoA synthetase (AceCS) from Leishmania donovani is involved in substrate recognition, catalysis and acetylation.
Topics: Acetate-CoA Ligase; Acetylation; Adenosine Monophosphate; Amino Acid Sequence; Biocatalysis; Conserved Sequence; Leishmania donovani; Leucine; Molecular Dynamics Simulation; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Processing, Post-Translational; Substrate Specificity | 2016 |
Use of Metabolomics to Trend Recovery and Therapy After Injury in Critically Ill Trauma Patients.
Topics: Adenosine Monophosphate; Adult; Biomarkers; Biotin; Case-Control Studies; Choline; Cytidine; Fatty Acids; Female; Humans; Injury Severity Score; Isoleucine; Leucine; Male; Metabolome; Metabolomics; Middle Aged; Muscle, Skeletal; Niacinamide; Nucleotides; Oxidative Stress; Principal Component Analysis; Prospective Studies; Serine; Time Factors; Valine; Wounds, Nonpenetrating | 2016 |
Public health round-up.
Topics: Adenosine Monophosphate; Alanine; Aminoisobutyric Acids; Anti-Bacterial Agents; Antibodies, Monoclonal; Benzimidazoles; Cyclopropanes; Democratic Republic of the Congo; Disease Outbreaks; Drug Resistance, Bacterial; Global Health; Hemorrhagic Fever, Ebola; Hepatitis C; Humans; Interinstitutional Relations; Lactams, Macrocyclic; Leucine; Malaria; Measles; Measles Vaccine; Poliomyelitis; Proline; Public Health Practice; Pyrrolidines; Quinoxalines; Randomized Controlled Trials as Topic; Ribonucleotides; Sulfonamides; Tuberculosis | 2019 |
Glutamate Dehydrogenase from Thermus thermophilus Is Activated by AMP and Leucine as a Complex with Catalytically Inactive Adenine Phosphoribosyltransferase Homolog.
Topics: Adenine Phosphoribosyltransferase; Adenosine Monophosphate; Bacterial Proteins; Catalysis; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Glutamate Dehydrogenase; Glutamic Acid; Leucine; Thermus thermophilus | 2019 |
Boceprevir, Calpain Inhibitors II and XII, and GC-376 Have Broad-Spectrum Antiviral Activity against Coronaviruses.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Caco-2 Cells; Carbonates; Cathepsin L; Cell Line; Chlorocebus aethiops; Coronavirus 229E, Human; Coronavirus 3C Proteases; Coronavirus NL63, Human; Coronavirus OC43, Human; COVID-19 Drug Treatment; Drug Combinations; Glycoproteins; HEK293 Cells; Humans; Leucine; Middle East Respiratory Syndrome Coronavirus; Oligopeptides; Proline; SARS-CoV-2; Serine Endopeptidases; Sulfonic Acids; Vero Cells | 2021 |
The race for antiviral drugs to beat COVID - and the next pandemic.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Birds; Clinical Trials as Topic; Coronavirus; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Cytidine; Drug Development; Drug Industry; Europe; Humans; Hydroxylamines; Indoles; Influenza, Human; Leucine; Orthomyxoviridae; Pandemics; Pyrrolidinones; Severe Acute Respiratory Syndrome; Strategic Stockpile; United States | 2021 |
Preclinical characterization of an intravenous coronavirus 3CL protease inhibitor for the potential treatment of COVID19.
Topics: Adenosine Monophosphate; Alanine; Animals; Chlorocebus aethiops; Coronavirus 229E, Human; Coronavirus 3C Proteases; Coronavirus Protease Inhibitors; COVID-19; COVID-19 Drug Treatment; Disease Models, Animal; Drug Design; Drug Synergism; Drug Therapy, Combination; HeLa Cells; Humans; Indoles; Infusions, Intravenous; Leucine; Mice; Pyrrolidinones; SARS-CoV-2; Severe acute respiratory syndrome-related coronavirus; Vero Cells | 2021 |
COVID-19 Therapeutics for Nonhospitalized Patients.
Topics: Adenosine Monophosphate; Alanine; Antibodies, Monoclonal, Humanized; Antibodies, Neutralizing; Antiviral Agents; Child; COVID-19 Drug Treatment; Cytidine; Drug Combinations; Female; Health Care Rationing; Humans; Hydroxylamines; Lactams; Leucine; Nitriles; Outpatients; Pregnancy; Proline; Ritonavir | 2022 |
Why scientists are racing to develop more COVID antivirals.
Topics: Adenosine Monophosphate; Administration, Oral; Alanine; Antiviral Agents; COVID-19; COVID-19 Drug Treatment; COVID-19 Vaccines; Cytidine; Drug Approval; Drug Combinations; Drug Development; Drug Resistance, Viral; Drug Therapy, Combination; Hospitalization; Humans; Hydroxylamines; Lactams; Leucine; Medication Adherence; Molecular Targeted Therapy; Mutagenesis; Nitriles; Proline; Public-Private Sector Partnerships; Research Personnel; Ritonavir; SARS-CoV-2 | 2022 |
Remdesivir, Molnupiravir and Nirmatrelvir remain active against SARS-CoV-2 Omicron and other variants of concern.
Topics: Adenosine; Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Cell Line; Chlorocebus aethiops; Coronavirus 3C Proteases; COVID-19 Drug Treatment; Cytidine; Humans; Hydroxylamines; Lactams; Leucine; Microbial Sensitivity Tests; Nitriles; Proline; RNA-Dependent RNA Polymerase; SARS-CoV-2; Vero Cells; Virus Replication | 2022 |
Treatment of COVID-19 in high-risk outpatients.
Topics: Adenosine Monophosphate; Alanine; Ambulatory Care; Antibodies, Monoclonal, Humanized; Antibodies, Neutralizing; Antiviral Agents; COVID-19; COVID-19 Drug Treatment; Cytidine; Drug Combinations; Humans; Hydroxylamines; Lactams; Leucine; Nitriles; Outpatients; Proline; Ritonavir; Treatment Outcome | 2022 |
Hundreds of COVID trials could provide a deluge of new drugs.
Topics: Adenosine Monophosphate; Administration, Oral; Alanine; Animals; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Neutralizing; Antiviral Agents; Clinical Trials as Topic; COVID-19; COVID-19 Drug Treatment; COVID-19 Vaccines; Cytidine; Depsipeptides; Dexamethasone; Drug Combinations; Drug Repositioning; Drug Synergism; Esters; Guanidines; Hospitalization; Host-Pathogen Interactions; Humans; Hydroxylamines; Internationality; Lactams; Leucine; Mice; National Institutes of Health (U.S.); Nitriles; Peptide Elongation Factor 1; Peptides, Cyclic; Proline; Protease Inhibitors; Ritonavir; RNA-Dependent RNA Polymerase; SARS-CoV-2; Serine Endopeptidases; Sodium-Glucose Transporter 2 Inhibitors; United States; Virus Replication | 2022 |