Page last updated: 2024-08-17

adenosine monophosphate and adenylosuccinate

adenosine monophosphate has been researched along with adenylosuccinate in 52 studies

Research

Studies (52)

TimeframeStudies, this research(%)All Research%
pre-199021 (40.38)18.7374
1990's11 (21.15)18.2507
2000's13 (25.00)29.6817
2010's6 (11.54)24.3611
2020's1 (1.92)2.80

Authors

AuthorsStudies
Kakiuchi, K; Matsuda, Y; Nakagawa, H; Ogawa, H; Shiraki, H1
Graff, JC; Plagemann, PG1
Goodman, MN; Lowenstein, JM1
Mack, DO; Smith, LD1
Jaeken, J; Van den Bergh, F; Van den Berghe, G; Vincent, MF4
Fromm, HJ; Soans, C1
Van den Berghe, G; Vincent, MF1
Biriukov, AI; Khomutov, RM; Zhukov, IuN1
Boulanger, Y; Ebel, JP; Giegé, R; Kern, D; Mejdoub, H; Reinbolt, J1
Dyken, ML1
Thomson, WH1
Bonsett, CA1
Iijima, K; Kogure, K; Onodera, H1
Holmes, EW; Patterson, D; Sabina, RL1
Holmes, EW; Manfredi, JP1
Bonsett, CA; Rudman, A1
Griffiths, JR; Shuttlewood, RJ1
Fitt, PS; Parliament, MB1
Cooney, DA; Jayaram, HN; Johnson, RK; Swiniarski, JK; Tyagi, AK1
Domkin, VD; Lazebnik, TA; Smirnov, MN1
Crifò, C; Salerno, C1
Fujimori, S1
Crifò, C; Lomonte, A; Salerno, C1
Bao, ZQ; Colman, RF; Dixon, JE; Lee, TT; Worby, C1
Boeglin, M; Delarue, M; Moras, D; Rees, B; Webster, G1
Marie, S; Race, V; Van den Berghe, G; Vincent, MF2
Li, Z; Lin, H; Luo, J; Wang, M; Zhu, Y1
Brosius, JL; Colman, RF1
Colman, RF; Palenchar, JB1
BALLIO, A; SERLUPI-CRESCENZI, G1
FROMM, HJ1
DAVEY, CL1
HAMPTON, A1
HANSEN, RG; OKUHARA, E1
Colman, RF; Segall, ML1
Colman, RF; Cowley, D; McGown, I; Patterson, D; Sivendran, S; Spiegel, E1
Akochy, PM; Bernier, S; Chênevert, R; Lapointe, J1
Alberty, RA1
Colman, RF; Lee, P1
Akochy, PM; Bernard, D; Bernier, S; Brousseau, OC; Chênevert, R; Fisette, O; Lapointe, J; Roy, PH1
Datsenko, KA; Kazakov, T; Metlitskaya, A; Novikova, M; Severinov, K; Vondenhoff, GH; Wanner, BL1
Kazakov, T; Metlytskaya, A; Novikova, M; Rozenski, J; Semenova, E; Severinov, K; Tikhonov, A; Van Aerschot, A; Vondenhoff, GH; Zukher, I1
Chen, BC; Duley, JA; Khoo, TB; McGown, IN; Ngu, LH; Pitt, J; Thong, MK; Yunus, ZM1
Agarwal, V; Datsenko, KA; Kazakov, T; Kuznedelov, K; Metlitskaya, A; Mukhamedyarov, D; Nair, S; Semenova, E; Severinov, K; Tikhonov, A; Van Aerschot, A; Vondenhoff, GH1
Arumugam, R; Dai, X; Ferdaoussi, M; Gooding, JR; Jensen, MV; Lu, D; MacDonald, PE; Newgard, CB; Wenner, BR1
Djukovic, D; Gu, H; O'Keefe, GE; Parent, BA; Raftery, D; Seaton, M; Sood, RF1
Bubić, A; Bzowska, A; Leščić Ašler, I; Luić, M; Mrnjavac, N; Stuparević, I; Wielgus-Kutrowska, B; Łyczek, M1
Campelj, DG; Goodman, CA; Hayes, A; Rybalka, E; Timpani, CA1

Reviews

1 review(s) available for adenosine monophosphate and adenylosuccinate

ArticleYear
[Adenylosuccinase deficiency].
    Ryoikibetsu shokogun shirizu, 1998, Issue:18 Pt 1

    Topics: Adenosine Monophosphate; Adenylosuccinate Lyase; Diagnosis, Differential; Humans; Mutation; Prognosis; Purine-Pyrimidine Metabolism, Inborn Errors

1998

Trials

1 trial(s) available for adenosine monophosphate and adenylosuccinate

ArticleYear
An Indiana study: an original clinical approach to a fatal metabolic problem.
    Indiana medicine : the journal of the Indiana State Medical Association, 1986, Volume: 79, Issue:3

    Topics: Adenosine Monophosphate; Adenosine Triphosphate; Clinical Trials as Topic; Humans; Male; Muscular Dystrophies

1986

Other Studies

50 other study(ies) available for adenosine monophosphate and adenylosuccinate

ArticleYear
Purification, crystallization, and properties of adenylosuccinate synthetase from rat skeletal muscle.
    Journal of biochemistry, 1977, Volume: 81, Issue:4

    Topics: Adenosine Monophosphate; Amino Acids; Animals; Aspartic Acid; Cations, Divalent; Cations, Monovalent; Fatty Acids, Nonesterified; Guanosine Triphosphate; Hydrogen-Ion Concentration; Inosine Nucleotides; Kinetics; Ligases; Male; Molecular Weight; Muscles; Nucleotides; Rats; Succinates

1977
Alanosine toxicity in Novikoff rat hepatoma cells due to inhibition of the conversion of inosine monophosphate to adenosine monophosphate.
    Cancer research, 1976, Volume: 36, Issue:4

    Topics: Adenine; Adenosine Monophosphate; Adenosine Triphosphate; Alanine; Aspartic Acid; Carcinoma, Hepatocellular; Cell Division; Cell Line; Cells, Cultured; Depression, Chemical; DNA, Neoplasm; Glucose; Hypoxanthines; Inosine Nucleotides; Liver Neoplasms; Mengovirus; Neoplasm Proteins; Neoplasms, Experimental; Nitroso Compounds; Purine Nucleotides; Pyrimidine Nucleotides; RNA, Neoplasm; Succinates; Uracil Nucleotides; Uridine

1976
The purine nucleotide cycle in skeletal muscle.
    Federation proceedings, 1978, Volume: 37, Issue:9

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Ammonia; Animals; Epinephrine; Inosine Monophosphate; Lactates; Muscles; Phosphocreatine; Physical Exertion; Purine Nucleotides; Rats; Succinates

1978
Isoelectrofocusing of rat muscle adenylosuccinase.
    Biochemistry international, 1991, Volume: 23, Issue:5

    Topics: Adenosine Monophosphate; Adenylosuccinate Lyase; Animals; Female; Fumarate Hydratase; Isoelectric Focusing; Isoenzymes; Methylphenazonium Methosulfate; Muscles; NADP; Rats; Rats, Inbred Strains; Staining and Labeling

1991
Adenylosuccinase activity and succinylpurine production in fibroblasts of adenylosuccinase-deficient children.
    Advances in experimental medicine and biology, 1991, Volume: 309B

    Topics: Adenosine Monophosphate; Adenylosuccinate Lyase; Aminoimidazole Carboxamide; Cells, Cultured; Child; Fibroblasts; Humans; Kinetics; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Ribonucleotides

1991
Radiochemical assay of adenylosuccinase: demonstration of parallel loss of activity toward both adenylosuccinate and succinylaminoimidazole carboxamide ribotide in liver of patients with the enzyme defect.
    Analytical biochemistry, 1991, Mar-02, Volume: 193, Issue:2

    Topics: Adenosine Monophosphate; Adenylosuccinate Lyase; Aminoimidazole Carboxamide; Animals; Carbon Radioisotopes; Chromatography, Thin Layer; Cold Temperature; Enzyme Stability; Fumarates; Humans; Liver; Male; Muscles; Rats; Rats, Inbred Strains; Ribonucleotides; Saccharomyces cerevisiae; Substrate Specificity

1991
Studies of ligand binding to Escherichia coli adenylosuccinate synthetase.
    Archives of biochemistry and biophysics, 1991, Nov-15, Volume: 291, Issue:1

    Topics: Adenosine Monophosphate; Adenylosuccinate Synthase; Binding Sites; Cysteine; Escherichia coli; Fluorescent Dyes; Guanosine Triphosphate; Inosine Monophosphate; Kinetics; Ligands; Naphthalenesulfonates; Protein Conformation; Rhodamines; Spectrometry, Fluorescence

1991
Influence of succinylpurines on the binding of adenosine to a particulate fraction of rat cerebral cortex.
    Advances in experimental medicine and biology, 1989, Volume: 253B

    Topics: Adenosine; Adenosine Monophosphate; Aminoimidazole Carboxamide; Animals; Cell Membrane; Cerebral Cortex; Imidazoles; Rats; Receptors, Purinergic; Ribonucleotides

1989
[Aspartyladenylate analog--effective inhibitor of asparagine synthetase].
    Bioorganicheskaia khimiia, 1988, Volume: 14, Issue:7

    Topics: Adenosine Monophosphate; Aspartate-Ammonia Ligase; Aspartic Acid; Chemical Phenomena; Chemistry; Ligases

1988
Covalent aspartylation of aspartyl-tRNA synthetase from bakers' yeast by its cognate aspartyl adenylate: identification of the labeled residues.
    Biochemistry, 1987, Apr-07, Volume: 26, Issue:7

    Topics: Adenosine Monophosphate; Amino Acid Sequence; Amino Acyl-tRNA Synthetases; Aspartate-tRNA Ligase; Aspartic Acid; Peptide Fragments; Saccharomyces cerevisiae

1987
Identifying and circumventing the defect in Duchenne muscular dystrophy: clinical and biochemical restoration after practical intervention.
    Medical hypotheses, 1987, Volume: 24, Issue:2

    Topics: Adenosine Monophosphate; Humans; Muscular Dystrophies

1987
Duchenne muscular dystrophy. A rational approach to disease comprehension and therapy.
    Indiana medicine : the journal of the Indiana State Medical Association, 1986, Volume: 79, Issue:3

    Topics: Adenosine Monophosphate; Adenosine Triphosphate; Elasticity; Humans; Lipid Metabolism; Muscle Contraction; Muscles; Muscular Dystrophies

1986
Mononucleotide metabolism in the rat brain after transient ischemia.
    Journal of neurochemistry, 1986, Volume: 46, Issue:6

    Topics: Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Brain; Chromatography, High Pressure Liquid; Cytidine Triphosphate; Guanine; Guanosine Diphosphate; Guanosine Triphosphate; Hypoxanthine; Hypoxanthines; Inosine; Inosine Monophosphate; Ischemic Attack, Transient; Male; Nucleotides; Phosphocreatine; Rats; Rats, Inbred Strains; Uridine Triphosphate

1986
5-Amino-4-imidazolecarboxamide riboside (Z-riboside) metabolism in eukaryotic cells.
    The Journal of biological chemistry, 1985, May-25, Volume: 260, Issue:10

    Topics: Adenosine Monophosphate; Aminoimidazole Carboxamide; Animals; Cells, Cultured; Cricetinae; Cricetulus; Female; Fibroblasts; Imidazoles; Inosine Monophosphate; Ovary; Purine Nucleotides; Pyrimidine Nucleotides; Ribonucleosides; Ribonucleotides

1985
Control of the purine nucleotide cycle in extracts of rat skeletal muscle: effects of energy state and concentrations of cycle intermediates.
    Archives of biochemistry and biophysics, 1984, Volume: 233, Issue:2

    Topics: Adenosine Monophosphate; Adenylosuccinate Lyase; Adenylosuccinate Synthase; AMP Deaminase; Animals; Energy Metabolism; Enzyme Activation; In Vitro Techniques; Inosine Monophosphate; Kinetics; Male; Muscles; Purine Nucleotides; Rats; Rats, Inbred Strains

1984
Duchenne's muscular dystrophy: a tissue culture perspective.
    Indiana medicine : the journal of the Indiana State Medical Association, 1984, Volume: 77, Issue:6

    Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Citric Acid Cycle; Culture Techniques; Humans; Lipid Metabolism; Muscles; Muscular Dystrophies

1984
The purine nucleotide profile in mouse, chicken and human dystrophic muscle: an abnormal ratio of inosine plus adenine nucleotides to guanine nucleotides.
    Clinical science (London, England : 1979), 1982, Volume: 62, Issue:1

    Topics: Adenine Nucleotides; Adenosine Monophosphate; Animals; Chickens; Child, Preschool; Guanine Nucleotides; Humans; Inosine Monophosphate; Male; Mice; Mice, Inbred C57BL; Muscles; Muscular Dystrophies; Muscular Dystrophy, Animal; Purine Nucleotides

1982
Purine nucleotide cycle enzymes in dystrophic and normal mouse muscle.
    Bioscience reports, 1982, Volume: 2, Issue:3

    Topics: Adenosine Monophosphate; Adenylosuccinate Lyase; AMP Deaminase; Animals; Lyases; Male; Mice; Mice, Inbred C57BL; Muscles; Muscular Dystrophy, Animal; Purine Nucleotides

1982
Studies on the mechanism of resistance of selected murine tumors to L-alanosine.
    Biochemical pharmacology, 1981, May-01, Volume: 30, Issue:9

    Topics: Adenosine Monophosphate; Alanine; Animals; Antibiotics, Antineoplastic; DNA; Drug Resistance; Leukemia L1210; Leukemia P388; Male; Mice; Neoplasms, Experimental; Nerve Tissue Proteins; Nitrosamines; Peptide Synthases; Succinates

1981
A new diagnostic technique for adenylosuccinate lyase deficiency.
    Journal of inherited metabolic disease, 1995, Volume: 18, Issue:3

    Topics: Adenosine Monophosphate; Adenylosuccinate Lyase; Aminoimidazole Carboxamide; Chromatography, Ion Exchange; Humans; Infant; Infant, Newborn; Purine-Pyrimidine Metabolism, Inborn Errors; Ribonucleosides; Spectrophotometry, Ultraviolet

1995
Microassay of adenylosuccinase by capillary electrophoresis.
    Analytical biochemistry, 1995, Apr-10, Volume: 226, Issue:2

    Topics: Adenosine; Adenosine Monophosphate; Adenylosuccinate Lyase; Electrophoresis; Erythrocytes; Humans; Lymphocytes

1995
Residual adenylosuccinase activities in fibroblasts of adenylosuccinase-deficient children: parallel deficiency with adenylosuccinate and succinyl-AICAR in profoundly retarded patients and non-parallel deficiency in a mildly retarded girl.
    Journal of inherited metabolic disease, 1993, Volume: 16, Issue:2

    Topics: Adenosine Monophosphate; Adenylosuccinate Lyase; Aminoimidazole Carboxamide; Binding, Competitive; Cells, Cultured; Child; Chromatography, Ion Exchange; Female; Fibroblasts; Humans; Hydrogen-Ion Concentration; Intellectual Disability; Kinetics; Nucleotides; Potassium Chloride; Ribonucleotides; Substrate Specificity

1993
Functional studies in fibroblasts of adenylosuccinase-deficient children.
    Journal of inherited metabolic disease, 1993, Volume: 16, Issue:2

    Topics: Adenosine Monophosphate; Adenosine Triphosphate; Adenylosuccinate Lyase; Aminoimidazole Carboxamide; Cells, Cultured; Child; Fibroblasts; Formates; Humans; Hypoxanthine; Hypoxanthines; Intellectual Disability; Ribonucleotides

1993
Inhibition of adenylosuccinate lyase by 2',3'-acyclic substrate analogs.
    Advances in experimental medicine and biology, 1998, Volume: 431

    Topics: Adenosine Monophosphate; Adenylosuccinate Lyase; Enzyme Inhibitors; Erythrocytes; Humans; Kinetics

1998
His68 and His141 are critical contributors to the intersubunit catalytic site of adenylosuccinate lyase of Bacillus subtilis.
    Biochemistry, 1999, Jan-05, Volume: 38, Issue:1

    Topics: Adenosine Monophosphate; Adenylosuccinate Lyase; Amino Acid Sequence; Amino Acid Substitution; Animals; Bacillus subtilis; Binding Sites; Catalysis; Chromatography, Gel; Circular Dichroism; Genetic Complementation Test; Histidine; Humans; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Recombinant Proteins; Sequence Alignment

1999
Aspartyl tRNA-synthetase from Escherichia coli: flexibility and adaptability to the substrates.
    Journal of molecular biology, 2000, Jun-23, Volume: 299, Issue:5

    Topics: Adenosine Monophosphate; Adenosine Triphosphate; Anticodon; Aspartate-tRNA Ligase; Aspartic Acid; Base Pairing; Binding Sites; Crystallography, X-Ray; Dimerization; Escherichia coli; Models, Molecular; Molecular Sequence Data; Pliability; Protein Structure, Secondary; Protein Structure, Tertiary; RNA, Transfer, Amino Acyl; Rotation

2000
Clinical, biochemical and molecular genetic correlations in adenylosuccinate lyase deficiency.
    Human molecular genetics, 2000, Sep-01, Volume: 9, Issue:14

    Topics: 5' Untranslated Regions; Adenosine Monophosphate; Adenylosuccinate Lyase; Aminoimidazole Carboxamide; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Genotype; Homozygote; Humans; Intellectual Disability; Kinetics; Metabolism, Inborn Errors; Mutation; Mutation, Missense; Recombinant Fusion Proteins; Recombinant Proteins; Ribonucleosides; Temperature; Time Factors

2000
Identification of estrogen-responsive genes in chick liver.
    Cell and tissue research, 2001, Volume: 305, Issue:3

    Topics: Adenosine Monophosphate; Animals; Chickens; Cycloheximide; Cytochrome P-450 Enzyme System; Egg Proteins, Dietary; Estrogens; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Liver; Ovomucin; Prostaglandin-Endoperoxide Synthases; Protein Synthesis Inhibitors; Transcription, Genetic

2001
Adenylosuccinate lyase deficiency: from the clinics to molecular biology.
    Advances in experimental medicine and biology, 2000, Volume: 486

    Topics: Adenosine; Adenosine Monophosphate; Adenylosuccinate Lyase; Aminoimidazole Carboxamide; Enzyme Stability; Gene Expression; Heating; Humans; Recombinant Fusion Proteins; Ribonucleotides

2000
Three subunits contribute amino acids to the active site of tetrameric adenylosuccinate lyase: Lys268 and Glu275 are required.
    Biochemistry, 2002, Feb-19, Volume: 41, Issue:7

    Topics: Adenosine Monophosphate; Adenylosuccinate Lyase; Alanine; Amino Acid Substitution; Arginine; Bacillus subtilis; Binding Sites; Circular Dichroism; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Genetic Complementation Test; Glutamic Acid; Kinetics; Light; Lysine; Molecular Weight; Mutagenesis, Site-Directed; Peptide Fragments; Protein Structure, Secondary; Scattering, Radiation; Tritium

2002
Characterization of a mutant Bacillus subtilis adenylosuccinate lyase equivalent to a mutant enzyme found in human adenylosuccinate lyase deficiency: asparagine 276 plays an important structural role.
    Biochemistry, 2003, Feb-25, Volume: 42, Issue:7

    Topics: Adenosine Monophosphate; Adenylosuccinate Lyase; Amino Acid Sequence; Aminoimidazole Carboxamide; Arginine; Asparagine; Bacillus subtilis; Bacterial Proteins; Circular Dichroism; Enzyme Activation; Humans; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Point Mutation; Protein Structure, Secondary; Recombinant Proteins; Ribonucleotides; Substrate Specificity; Threonine

2003
Isolation of adenylosuccinic acid from Penicillium chrysogenum.
    Nature, 1957, Jan-19, Volume: 179, Issue:4551

    Topics: Adenosine Monophosphate; Nucleotides; Penicillium; Penicillium chrysogenum; Succinates

1957
On the equilibrium and mechanism of adenylosuccinic acid synthesis.
    Biochimica et biophysica acta, 1958, Volume: 29, Issue:2

    Topics: Adenosine Monophosphate; Biochemical Phenomena; Nucleosides; Nucleotides

1958
Synthesis of adenylosuccinic acid in preparations of mammalian skeletal muscle.
    Nature, 1959, Apr-04, Volume: 183, Issue:4666

    Topics: Adenosine Monophosphate; Animals; Mammals; Muscle, Skeletal; Muscles; Nucleosides; Nucleotides

1959
Studies of the action of adenylosuccinase with 6-thio analogues of adenylosuccinic acid.
    The Journal of biological chemistry, 1962, Volume: 237

    Topics: Adenine Nucleotides; Adenosine Monophosphate; Adenylosuccinate Lyase; Enzymes; Organic Chemicals; Phosphates

1962
REINVESTIGATION OF BOVINE LIVER NUCLEOTIDE-PEPTIDE AND SEPARATION OF ADENYLOSUCCINIC ACID (6-SUCCINOAMINOPURINE-9-RIBOSYL-5'-PHOSPHATE).
    Journal of biochemistry, 1964, Volume: 55

    Topics: Adenine Nucleotides; Adenosine Monophosphate; Animals; Cattle; Chromatography; Freeze Drying; Glycosides; Liver; Nucleotides; Peptides; Phosphates; Research; Succinates; Ultraviolet Rays

1964
Gln212, Asn270, and Arg301 are critical for catalysis by adenylosuccinate lyase from Bacillus subtilis.
    Biochemistry, 2004, Jun-15, Volume: 43, Issue:23

    Topics: Adenosine Monophosphate; Adenylosuccinate Lyase; Amino Acid Sequence; Animals; Arginine; Asparagine; Bacillus subtilis; Binding Sites; Catalysis; Circular Dichroism; Glutamine; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Protein Structure, Tertiary; Sequence Alignment; Thermodynamics

2004
Two novel mutant human adenylosuccinate lyases (ASLs) associated with autism and characterization of the equivalent mutant Bacillus subtilis ASL.
    The Journal of biological chemistry, 2004, Dec-17, Volume: 279, Issue:51

    Topics: Adenosine Monophosphate; Adenylosuccinate Lyase; Amino Acid Sequence; Arginine; Aspartic Acid; Autistic Disorder; Bacillus subtilis; Circular Dichroism; DNA; Electrophoresis, Polyacrylamide Gel; Family Health; Female; Glutamic Acid; Heterozygote; Hot Temperature; Humans; Hydrogen-Ion Concentration; Kinetics; Male; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mothers; Mutagenesis, Site-Directed; Mutation; Polymerase Chain Reaction; Protein Binding; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Spectrophotometry; Temperature; Thermotoga maritima; Time Factors; Ultraviolet Rays

2004
Synthesis and aminoacyl-tRNA synthetase inhibitory activity of aspartyl adenylate analogs.
    Bioorganic & medicinal chemistry, 2005, Jan-03, Volume: 13, Issue:1

    Topics: Adenosine Monophosphate; Amino Acyl-tRNA Synthetases; Aspartic Acid; Enzyme Inhibitors; Escherichia coli; Magnetic Resonance Spectroscopy; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared

2005
Thermodynamics of the purine nucleotide cycle.
    Biophysical chemistry, 2006, Jun-20, Volume: 122, Issue:1

    Topics: Adenosine Monophosphate; Guanosine Diphosphate; Guanosine Triphosphate; Hydrogen-Ion Concentration; Osmolar Concentration; Phosphates; Purine Nucleotides; Thermodynamics

2006
Expression, purification, and characterization of stable, recombinant human adenylosuccinate lyase.
    Protein expression and purification, 2007, Volume: 51, Issue:2

    Topics: Adenosine Monophosphate; Adenylosuccinate Lyase; Circular Dichroism; Cloning, Molecular; Enzyme Activation; Enzyme Stability; Escherichia coli; Humans; Hydrogen-Ion Concentration; Kinetics; Oxidation-Reduction; Protein Structure, Quaternary; Protein Structure, Secondary; Recombinant Proteins; Sulfhydryl Compounds; Temperature

2007
Inhibition by L-aspartol adenylate of a nondiscriminating aspartyl-tRNA synthetase reveals differences between the interactions of its active site with tRNA(Asp) and tRNA(Asn).
    Journal of enzyme inhibition and medicinal chemistry, 2007, Volume: 22, Issue:1

    Topics: Adenosine Monophosphate; Aspartate-tRNA Ligase; Aspartic Acid; Base Sequence; Binding Sites; DNA Primers; Enzyme Inhibitors; Nucleic Acid Conformation; RNA, Transfer, Asn; RNA, Transfer, Asp

2007
Escherichia coli peptidase A, B, or N can process translation inhibitor microcin C.
    Journal of bacteriology, 2008, Volume: 190, Issue:7

    Topics: Adenosine Monophosphate; Aminopeptidases; Aspartate-tRNA Ligase; Aspartic Acid; Bacterial Proteins; Bacteriocins; Escherichia coli; Escherichia coli Proteins; Mass Spectrometry; Metalloendopeptidases; Molecular Structure; Mutation; Peptide Hydrolases; Serine Endopeptidases

2008
MccE provides resistance to protein synthesis inhibitor microcin C by acetylating the processed form of the antibiotic.
    The Journal of biological chemistry, 2010, Apr-23, Volume: 285, Issue:17

    Topics: Acetyltransferases; Adenosine Monophosphate; Anti-Bacterial Agents; Aspartate-tRNA Ligase; Aspartic Acid; Bacteriocins; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Proteins; Ferrichrome; Multigene Family; Protein Biosynthesis

2010
Adenylosuccinate lyase deficiency in a Malaysian patient, with novel adenylosuccinate lyase gene mutations.
    Journal of inherited metabolic disease, 2010, Volume: 33 Suppl 3

    Topics: Adenosine; Adenosine Monophosphate; Adenylosuccinate Lyase; Aminoimidazole Carboxamide; Autistic Disorder; Biomarkers; Child Development; Chromatography, High Pressure Liquid; DNA Mutational Analysis; Genetic Predisposition to Disease; Genetic Testing; Heterozygote; Humans; Infant; Infant, Newborn; Malaysia; Male; Mutation; Myoclonus; Phenotype; Predictive Value of Tests; Psychomotor Disorders; Psychomotor Performance; Purine-Pyrimidine Metabolism, Inborn Errors; Ribonucleosides; Seizures; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2010
The RimL transacetylase provides resistance to translation inhibitor microcin C.
    Journal of bacteriology, 2014, Volume: 196, Issue:19

    Topics: Acetyltransferases; Adenosine Monophosphate; Aspartic Acid; Bacteriocins; Escherichia coli; Escherichia coli Proteins; Peptide Chain Initiation, Translational

2014
Adenylosuccinate Is an Insulin Secretagogue Derived from Glucose-Induced Purine Metabolism.
    Cell reports, 2015, Oct-06, Volume: 13, Issue:1

    Topics: Adenosine Monophosphate; Adenylosuccinate Lyase; Adenylosuccinate Synthase; Animals; Cell Line, Tumor; Cysteine Endopeptidases; Diabetes Mellitus, Type 2; Endopeptidases; Enzyme Inhibitors; Exocytosis; Gene Expression Regulation; Glucose; Guanine; Humans; Inosine Monophosphate; Insulin; Insulin Secretion; Insulin-Secreting Cells; Metabolome; Mycophenolic Acid; Patch-Clamp Techniques; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Signal Transduction

2015
Use of Metabolomics to Trend Recovery and Therapy After Injury in Critically Ill Trauma Patients.
    JAMA surgery, 2016, 07-20, Volume: 151, Issue:7

    Topics: Adenosine Monophosphate; Adult; Biomarkers; Biotin; Case-Control Studies; Choline; Cytidine; Fatty Acids; Female; Humans; Injury Severity Score; Isoleucine; Leucine; Male; Metabolome; Metabolomics; Middle Aged; Muscle, Skeletal; Niacinamide; Nucleotides; Oxidative Stress; Principal Component Analysis; Prospective Studies; Serine; Time Factors; Valine; Wounds, Nonpenetrating

2016
In the quest for new targets for pathogen eradication: the adenylosuccinate synthetase from the bacterium Helicobacter pylori.
    Journal of enzyme inhibition and medicinal chemistry, 2018, Volume: 33, Issue:1

    Topics: Adenosine Monophosphate; Adenylosuccinate Synthase; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glycine; Helicobacter pylori; Molecular Structure; Structure-Activity Relationship

2018
Adenylosuccinic acid: a novel inducer of the cytoprotectant Nrf2 with efficacy in Duchenne muscular dystrophy.
    Current medical research and opinion, 2021, Volume: 37, Issue:3

    Topics: Adenosine Monophosphate; Animals; Disease Models, Animal; Humans; Mice; Mice, Inbred mdx; Muscle, Skeletal; Muscular Dystrophy, Duchenne; NF-E2-Related Factor 2

2021