adenosine diphosphate ribose has been researched along with guanosine 5'-o-(3-thiotriphosphate) in 196 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 56 (28.57) | 18.7374 |
| 1990's | 129 (65.82) | 18.2507 |
| 2000's | 10 (5.10) | 29.6817 |
| 2010's | 1 (0.51) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Deppisch, H; Mollner, S; Pfeuffer, T | 1 |
| Grenfell, S; Kennard, N; Ray, K; Rollins, P; Smithers, N; Solari, R; Thompson, N; Witham, S | 1 |
| Oswald, RE; Willard, JM; Ziegra, CJ | 1 |
| Kowluru, A; Kowluru, RA; Yamazaki, A | 1 |
| Hashimoto, H; Ichikawa, A; Negishi, M | 1 |
| Landau, M; Taggart, P | 1 |
| Heinstein, PF; Legendre, L; Low, PS | 1 |
| Chen, CH; Sugai, M; Wu, HC | 1 |
| Mitchell, J; Northup, JK; Schimmer, BP | 1 |
| Anand-Srivastava, MB | 2 |
| Cha, BY; Davis, HW; Jo, H; McDonald, JM | 1 |
| Birnbaumer, L; Codina, J; Shibano, T; Vanhoutte, PM | 1 |
| Katada, T; Kurosu, H; Takahashi, K; Takei, Y | 1 |
| Denker, BM; Neer, EJ; Schmidt, CJ | 1 |
| Bokoch, GM; Bommakanti, RK; Jesaitis, AJ; Klotz, KN; Schreiber, RE; Siemsen, DW; Tolley, JO | 1 |
| Hirata, K; Kaibuchi, K; Kikuchi, A; Kuroda, S; Matsuura, Y; Saida, K; Sasaki, T; Seki, H; Takai, Y | 1 |
| Casey, PJ; Didsbury, JR; Ménard, L; Snyderman, R; Tomhave, E; Uhing, RJ | 1 |
| Chiba, K; Hoshi, M; Katada, T; Tadenuma, H; Takahashi, K | 1 |
| Ermel, B; Häring, HU; Kellerer, M; Mushack, J; Obermaier-Kusser, B; Pröfrock, A; Schleicher, E; Seffer, E | 1 |
| Nishimoto, I; Ogata, E; Okamoto, T | 1 |
| Blank, JL; Exton, JH; Ross, AH | 1 |
| Klein, JB; McLeish, KR; Schepers, T; Sonnenfeld, G | 1 |
| Iiri, T; Katada, T; Ohoka, Y; Ui, M | 1 |
| Baldi, E; Dunn, MJ; Kester, M; Simonson, MS; Thomas, CP | 1 |
| Figler, RA; Garrison, JC; Graber, SG | 1 |
| Hirai, A; Kato, I; Noda, M; Seki, K; Tamura, Y; Yoshida, S | 1 |
| Maitre, M; Rumigny, JF; Sauvage, C | 1 |
| Fleischer, B; Gerardy-Schahn, R; Mittrücker, HW; Schultze, U | 1 |
| Aunis, D; Bader, MF; Rouot, B; Sontag, JM; Thierse, D | 1 |
| Audigier, Y; Bockaert, J; Journot, L; Pantaloni, C | 2 |
| Jaffe, LA; Kline, D; Kopf, GS; Muncy, LF | 1 |
| Dunn, MJ; Kester, M; Thomas, CP | 1 |
| Ichikawa, A; Negishi, M; Takahashi, S | 1 |
| Pröfrock, A; Schnefel, S; Schulz, I | 1 |
| Chen, JC; Dickey, BF; Fishman, JB; Rubins, JB; Volicer, L | 1 |
| Dieterich, K; Gierschik, P; Jakobs, KH; Moghtader, R; Straub, C | 1 |
| Kahn, RA | 1 |
| Golly, F; Larocca, JN; Ledeen, RW | 1 |
| Imaizumi, T; Watanabe, Y; Yoshida, H | 1 |
| Hamm, HE; Kaufman, LS; Rasenick, MM; Warpeha, KM | 1 |
| Burdett, E; Klip, A; Mills, GB | 1 |
| Bellorin-Font, E; Lopez, C; Milanes, CL; Paz-Martinez, V; Pernalete, N; Starosta, R; Weisinger, J | 1 |
| Ito, H; Katada, T; Kobayashi, I; Kurachi, Y; Shibasaki, H; Takahashi, K; Tohyama, K; Ui, M | 1 |
| Pang, IH; Sternweis, PC | 1 |
| Berti-Mattera, L; Chang, CH; Douglas, J; Hopfer, U; Sims, C; Zhou, J | 1 |
| Barnett, JV; Galper, JB; Griendling, KK; Lassegue, B; Shamah, SM | 1 |
| Fein, A; Hamm, HE; Lisman, JE; Robinson, PR; Szuts, EZ; Wood, SF | 1 |
| Behl, B; Kaever, V; Resch, K; Schwinzer, R; Sommermeyer, H | 1 |
| Babich, M; King, KL; Nissenson, RA | 1 |
| Couvineau, A; Laburthe, M; Rouyer-Fessard, C; Voisin, T | 1 |
| Alexander, RW; Griendling, KK; Socorro, L | 1 |
| Teitelbaum, I | 1 |
| Delespesse, G; Dugas, B; Genot, E; Kolb, JP; Petit-Koskas, E; Poggioli, J; Renard, D; Sarfati, M | 1 |
| Katada, T; Matsubara, T; Tohkin, M; Yagami, T | 1 |
| Hermouet, S; Lanotte, M; Milligan, G | 1 |
| Neer, EJ; Van Amsterdam, JR; Winslow, JW | 1 |
| Chan, CK; Chan, KC; Moscarello, MA; Ramwani, J; Ranwani, J | 1 |
| Lindau, M | 1 |
| Furuyama, S; Hara-Yokoyama, M | 1 |
| Bokoch, GM; Lacal, JC; Quilliam, LA | 1 |
| Audigier, Y; Bockaert, J; Journot, L | 1 |
| Haldar, S; Monroe, JG | 1 |
| Bilezikian, JP; Hatcher, V; Morris, SA; Tanowitz, HB; Weiss, LM; Wittner, M | 1 |
| Forte, M; Quan, F; Spiegel, A; Thambi, NC; Wolfgang, WJ | 1 |
| Lancet, D; Mollner, S; Pfeuffer, E; Pfeuffer, T | 1 |
| Beeler, T; Carrier, L; Dupont, Y; Robert, M; Rouot, B; Toutant, M; Villaz, M | 1 |
| Balestre, MN; Berrada, R; Guillon, G; Lombard, C; Mouillac, B | 1 |
| Agata, K; Eguchi, G; Kitamura, Y; Kodama, R; Mochii, M; Nomura, Y; Watanabe, K | 1 |
| Boulias, C; Moscarello, MA | 1 |
| Gierschik, P; Hekman, M; Helmreich, EJ; Holzhöfer, A; Im, MJ; Jakobs, KH; Pfeuffer, T | 1 |
| Axelrod, J; Burch, RM; Jelsema, C | 1 |
| Osawa, T; Toyoshima, S; Wang, P | 1 |
| Imamura, K; Kufe, D; Sherman, ML; Spriggs, D | 1 |
| Furukawa, K; Hasunuma, K; Miyamoto-Shinohara, Y | 1 |
| Asano, T; Ogasawara, N | 1 |
| Aub, DL; Cote, TE; Frey, EA; Sekura, RD | 1 |
| Lapetina, EG | 1 |
| Huff, RM; Neer, EJ | 1 |
| Bauer, S; Jakobs, KH | 1 |
| Katada, T; Oinuma, M; Ui, M | 2 |
| Gilman, AG; Kahn, RA | 1 |
| Bentley, JK; Domino, SE; Garbers, DL; Noland, TD; Van Dop, C | 1 |
| Katada, T; Oinuma, M; Ui, M; Yokosawa, H | 1 |
| Endo, Y; Kopf, GS; Lee, MA | 1 |
| Gierschik, P; Jakobs, KH; Sidiropoulos, D; Spiegel, A | 1 |
| Kubo, S; Kurihara, K; Matsuoka, I; Syoto, B; Syuto, B | 1 |
| Birnbaumer, L; Codina, J; Mattera, R; Sekura, RD | 1 |
| Casey, PJ; Gilman, AG; Graziano, MP | 1 |
| Furukawa, K; Hasunuma, K; Mukai, C; Nakamura, T; Tomita, K | 1 |
| Gierschik, P; Jakobs, KH | 1 |
| Aktories, K; Frevert, J | 1 |
| Adamik, R; Chang, PP; Chen, HC; Moss, J; Noda, M; Tsai, SC; Vaughan, M | 1 |
| Kahler, KR; Schimerlik, MI; Tota, MR | 1 |
| Banfic, H; Eckhardt, L; Schnefel, S; Schultz, G; Schulz, I | 1 |
| Higashijima, T; Nakajima, T; Ross, EM; Uzu, S | 1 |
| Konishi-Imamura, L; Nakano, H; Noda, M; Nomura, Y; Tohda, M | 1 |
| Gallin, JI; Malech, HL; Rotrosen, D; Spiegel, AM | 1 |
| Estey, SJ; Mansour, TE | 1 |
| Fujiwara, M; Imura, H; Morii, N; Nakao, K; Narumiya, S; Ohashi, Y; Sekine, A | 1 |
| Fujita, T; Kikuchi, A; Takai, Y; Yamamoto, K | 1 |
| Audigier, Y; Blobel, G; Nigam, SK | 1 |
| Fung, BK; Navon, SE | 1 |
| Coburn, J; Gill, DM | 1 |
| Gilman, AG; Northup, JK; Smigel, MD | 1 |
| Gill, DM; Meren, R | 1 |
| Bokoch, GM; Gilman, AG; Katada, T; Northup, JK; Ui, M | 2 |
| Garciá-Sáinz, JA; Malbon, CC; Rapiejko, PJ | 1 |
| Robishaw, JD; Sternweis, PC | 1 |
| Gerasimenko, O; Petersen, OH; Thorn, P | 1 |
| Hescheler, J | 1 |
| Imai, A; Nashida, T; Shimomura, H | 1 |
| Dubois, DH; Gong, X; Miller, DJ; Shur, BD | 1 |
| Fujita, A; Hata, F; Nakajima, H; Nishio, H; Takeuchi, T | 1 |
| Hoon, MA; Margolskee, RF; Northup, JK; Ryba, NJ | 1 |
| Lange, AB; Orchard, I; Wang, Z | 1 |
| Kahn, RA; Randazzo, PA | 1 |
| Abebe, W; Agrawal, DK; Edwards, JD | 1 |
| Olianas, MC; Onali, P | 2 |
| Jakobs, KH; Wieland, C; Wieland, T | 1 |
| Benovic, JL; Gout, I; Rittenhouse, SE; Sugai, M; Wetzker, R; Zhang, J | 1 |
| Arruda, JA; Qiu, YY; Ruiz, OS; Wang, LJ | 1 |
| Exton, JH; Malcolm, KC; Qiu, RG; Ross, AH; Symons, M | 1 |
| Inanobe, A; Katada, T; Kobayashi, I; Kontani, K; Nishina, H; Ohoka, Y; Takahashi, K | 1 |
| Dhanasekaran, N; Ruoho, AE; Vaillancourt, RR | 1 |
| Sommer, D; Song, PS | 1 |
| Ervens, J; Grünbaum, L; Hagelüken, A; Harhammer, R; Heilmann, I; Klinker, JF; Nürnberg, B; Offermanns, S; Schwaner, I; Wenzel-Seifert, K | 1 |
| Emala, CW; Hirshman, CA; Jacoby, DB; Levine, MA; Proud, D; Yang, J | 1 |
| Clark, MA; Egan, RW; Korte, A | 1 |
| Ogawa, K; Schacht, J | 1 |
| Levine, MA; Martin, CS; McCaul, ME; Waltman, C; Wand, GS; Wolfgang, D | 1 |
| Akita, Y; Katada, T; Saito, T; Yajima, Y | 1 |
| Akino, T; Fukada, Y; Kokame, K; Matsuda, T; Shimonishi, Y; Takao, T; Yoshizawa, T | 1 |
| Haun, RS; Hong, JX; Moss, J; Tsai, SC; Vaughan, M | 1 |
| Okuya, S; Rebois, RV; Toyoshige, M | 1 |
| Barritt, GJ; Berven, LA; Hughes, BP | 1 |
| Caro, JF; Caro, M; Exton, JH; Lynch, CJ; Poulos, J; Raju, MS; Thakkar, JK | 1 |
| Dillon, S; Feig, L; Hall, A; King, WG; Rittenhouse, SE; Zhang, J | 1 |
| Lander, HM; Novogrodsky, A; Sehajpal, PK | 1 |
| Klein, JB; Lederer, ED; McLeish, KR | 1 |
| Audigier, Y; Bockaert, J; Nebout, I; Pantaloni, C; van der Neut, R | 1 |
| al-Aoukaty, A; Gluck, S; Ho, AD; Maghazachi, AA; Sebok, K; Woodside, D | 1 |
| Amino, N; Nishiyama, S; Tada, H; Takada, K; Takano, T | 1 |
| Audigier, Y; Pantaloni, C | 1 |
| Banno, Y; Kumada, T; Nozawa, Y; Sakai, T | 1 |
| Bilezikian, JP; Camacho, JA; Chen, G; Glusman, J; Morris, SA; Rohde, S | 1 |
| Simon, MI; Slepak, VZ; Wilkie, TM | 1 |
| Diehl, AM; Levine, MA; Samy, S; Wand, GS; Wolfgang, D | 1 |
| Griffiths, G; Hoflack, B; Le Borgne, R | 1 |
| Cerione, RA; Erickson, JW; Mittal, R | 1 |
| Benos, DJ; Berdiev, BK; Fuller, CM; Ismailov, II; Jovov, B; Keeton, DA | 1 |
| Beaudry, C; Bellabarba, D; Fortier, S; Gallo-Payet, N; Giguère, A | 1 |
| Mansfield, PJ; Suchard, SJ | 1 |
| Pratt, RE; Zhang, J | 1 |
| Calvo, JR; Carrero, I; Guijarro, LG; Pozo, D; Prieto, JC; Segura, JJ | 1 |
| Abebe, W; Agrawal, DK; Joshi, S | 1 |
| Okuya, S; Rebois, RV; Warner, DR | 1 |
| Amano, I; Eguchi, T; Ishida, H; Ishikawa, Y | 1 |
| Aktories, K; Hofmann, F; Just, I; Mann, M; Rex, G; Selzer, J; Wilm, M | 1 |
| Aktories, K; Just, I; Otto, B; Pfitzer, G; Steusloff, A | 1 |
| Abousalham, A; Brindley, DN; Liossis, C; O'Brien, L | 1 |
| Gillison, SL; Sharp, GW; Straub, SG | 1 |
| Exton, JH; Kanoh, H; Williger, BT | 1 |
| Horibe, S; Imai, A; Takagi, A; Tamaya, T | 1 |
| Kather, H; Krieger-Brauer, HI; Medda, PK | 1 |
| Soloff, MS; Strakova, Z | 1 |
| Amin, RH; Bondarenko, VA; Desai, M; Dua, S; Hayashi, F; Jackson, KW; Kinumi, T; Komori, N; Lipkin, VM; Matsumoto, H; Ohashi, M; Usukura, J; Yamazaki, A; Yamazaki, M; Yousif, KK | 1 |
| Asahi, T; Ishikawa, A; Iwasaki, Y; Kaidoh, T; Kato, T | 1 |
| Cahill, PA; McKillop, IH; Schmidt, CM; Sitzmann, JV | 1 |
| Breivogel, CS; Childers, SR; Selley, DE | 1 |
| Ashley, CC; Hodson, EA; Hughes, AD; Lymn, JS | 1 |
| Hong, JX; Lee, FJ; Lin, CY; Moss, J; Patton, WA; Vaughan, M | 1 |
| Béliveau, R; Desrosiers, RR; Gauthier, F; Lin, W | 1 |
| Baines, DL; Fyfe, GK; Gambling, L; Kemp, PJ; Olver, RE | 1 |
| Exton, JH; Guillemain, I | 1 |
| Hillemann, J; Majoul, I; Pepperkok, R; Pizza, M; Sohn, K; Söling, HD; Wieland, FT | 1 |
| Mies, F; Sariban-Sohraby, S; Svoboda, M | 1 |
| Maekawa, M; Miyazaki, H; Murayama, T; Narita, H; Nomura, Y; Ono, S | 1 |
| Brown, JH; Kaplan, DD; Majumdar, M; Seasholtz, TM | 1 |
| Hirata, M; Kanematsu, T; Misumi, Y; Takeuchi, H | 1 |
| Chen, CA; Manning, DR; Wang, Y; Windh, RT | 1 |
| Ganpat, MM; Nishimura, M; Okuya, S; Pointer, RH; Rebois, RV; Toyoshige, M | 1 |
| Artemyev, NO; Muradov, KG | 1 |
| Dipierro, CG; Liu, X; Longenecker, K; Nakamoto, RK; Read, PW; Somlyo, AP; Somlyo, AV; Walker, LA | 1 |
| Corrèze, C; Dib, K; Lambert, B | 1 |
| Fukada, Y; Matsuda, T | 1 |
| Giusto, NM; Pasquaré, SJ; Roque, ME; Salvador, GA | 1 |
| Hashii, M; Higashida, C; Higashida, H; Shintaku, M; Takeda, Y; Zhang, J | 1 |
| Artemyev, NO; Moussaif, M; Natochin, M | 1 |
| Katada, T; Kontani, K; Kurose, H; Nagano, T; Nagao, T; Nishida, M; Schey, KL; Takagahara, S; Urano, Y | 1 |
| King, MM; Phelps, SH; Varker, KA; Williams, CL | 1 |
| Bavec, A; Deželak, M | 1 |
196 other study(ies) available for adenosine diphosphate ribose and guanosine 5'-o-(3-thiotriphosphate)
| Article | Year |
|---|---|
The alpha subunit of the stimulatory guanine-nucleotide-binding regulatory protein forms high-molecular-mass aggregates, concomitant with iloprost-induced desensitization of human platelet adenylyl cyclase.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Blood Platelets; Blotting, Western; Centrifugation, Density Gradient; Cholera Toxin; Cross-Linking Reagents; Erythrocytes; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Iloprost; Macromolecular Substances; Molecular Weight; Turkeys | 1992 |
Investigation of guanine-nucleotide-binding protein involvement and regulation of cyclic AMP metabolism in interleukin 1 signal transduction.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cell Line; Cell Membrane; Cyclic AMP; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanylyl Imidodiphosphate; Interleukin-1; Kinetics; Membrane Proteins; NAD; Receptors, Immunologic; Receptors, Interleukin-1; Recombinant Proteins; Signal Transduction; Virulence Factors, Bordetella | 1992 |
The interaction of a kainate receptor from goldfish brain with a pertussis toxin-sensitive GTP binding protein.
Topics: Adenosine Diphosphate Ribose; Animals; Goldfish; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanylyl Imidodiphosphate; Kainic Acid; Kinetics; Pertussis Toxin; Receptors, Kainic Acid; Receptors, Neurotransmitter; Virulence Factors, Bordetella | 1992 |
Functional alterations of G-proteins in diabetic rat retina: a possible explanation for the early visual abnormalities in diabetes mellitus.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Animals; Cyclic GMP; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Glucose; Glycosylation; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Kinetics; Pertussis Toxin; Rats; Rats, Inbred Strains; Retina; Rod Cell Outer Segment; Transducin; Virulence Factors, Bordetella | 1992 |
Translocation of alpha subunits of stimulatory guanine nucleotide-binding proteins through stimulation of the prostacyclin receptor in mouse mastocytoma cells.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Blotting, Western; Cell Membrane; Cholera Toxin; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Iloprost; Mast-Cell Sarcoma; Mice; Receptors, Epoprostenol; Receptors, Prostaglandin; Tumor Cells, Cultured | 1992 |
Characterization of a G-protein from the mandibular organ of the lobster Homarus americanus (Nephropidae, Decapoda).
Topics: Adenosine Diphosphate Ribose; Animals; Cattle; Cell Membrane; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Male; Nephropidae | 1992 |
Evidence for participation of GTP-binding proteins in elicitation of the rapid oxidative burst in cultured soybean cells.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Cells, Cultured; Cholera Toxin; DNA; Electrophoresis, Polyacrylamide Gel; Glycine max; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Immunoglobulin Fab Fragments; Intercellular Signaling Peptides and Proteins; Molecular Sequence Data; Niacinamide; Peptides; Respiratory Burst; Sequence Homology, Amino Acid; Signal Transduction; Wasp Venoms | 1992 |
Bacterial ADP-ribosyltransferase with a substrate specificity of the rho protein disassembles the Golgi apparatus in Vero cells and mimics the action of brefeldin A.
Topics: 4-Chloro-7-nitrobenzofurazan; Adenosine Diphosphate Ribose; Animals; Bacterial Proteins; Biomarkers; Brefeldin A; Ceramides; Coatomer Protein; Colforsin; Cyclopentanes; Golgi Apparatus; Guanosine 5'-O-(3-Thiotriphosphate); Mannosidases; Microtubule-Associated Proteins; Poly(ADP-ribose) Polymerases; Rho Factor; Staphylococcus aureus; Substrate Specificity; Vero Cells | 1992 |
Defective guanyl nucleotide-binding protein beta gamma subunits in a forskolin-resistant mutant of the Y1 adrenocortical cell line.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adrenal Cortex Neoplasms; Animals; Brain; Cattle; Cell Membrane; Chromatography, Gel; Clone Cells; Colforsin; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Kinetics; Macromolecular Substances; Mice; Mutagenesis; Pertussis Toxin; Rats; Rod Cell Outer Segment; Transducin; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1992 |
Enhanced expression of inhibitory guanine nucleotide regulatory protein in spontaneously hypertensive rats. Relationship to adenylate cyclase inhibition.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Angiotensin II; Animals; Aorta; Atrial Natriuretic Factor; Cholera Toxin; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hypertension; Immunoblotting; Myocardium; Oxotremorine; Pertussis Toxin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Virulence Factors, Bordetella | 1992 |
Identification, partial purification, and characterization of two guanosine triphosphate-binding proteins associated with insulin receptors.
Topics: Adenosine Diphosphate Ribose; Adipose Tissue; Animals; Cell Membrane; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Immunoblotting; Insulin; Male; Pertussis Toxin; Placenta; Rats; Rats, Sprague-Dawley; Receptor, Insulin; Virulence Factors, Bordetella | 1992 |
Guanosine 5'-O-(3-thiotriphosphate) causes endothelium-dependent, pertussis toxin-sensitive relaxations in porcine coronary arteries.
Topics: Adenosine Diphosphate Ribose; Animals; Arginine; Coronary Vessels; Dinoprost; Endothelium, Vascular; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Kinetics; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroarginine; Pertussis Toxin; Saponins; Sodium Fluoride; Swine; Virulence Factors, Bordetella | 1992 |
A GTP-binding protein in rat liver nuclei serving as the specific substrate of pertussis toxin-catalyzed ADP-ribosylation.
Topics: Adenosine Diphosphate Ribose; Animals; Carbon Tetrachloride; Cell Nucleus; GTP-Binding Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Kinetics; Liver; Macromolecular Substances; Male; Pertussis Toxin; Rats; Rats, Inbred Strains; Substrate Specificity; Virulence Factors, Bordetella | 1992 |
Mutagenesis of the amino terminus of the alpha subunit of the G protein Go. In vitro characterization of alpha o beta gamma interactions.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Animals; Cattle; Centrifugation, Density Gradient; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Macromolecular Substances; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Myristic Acid; Myristic Acids; Peptide Mapping; Pertussis Toxin; Polymerase Chain Reaction; Protein Biosynthesis; Rabbits; Rats; Reticulocytes; RNA, Messenger; Sequence Homology, Nucleic Acid; Transcription, Genetic; Virulence Factors, Bordetella | 1992 |
Reconstitution of a physical complex between the N-formyl chemotactic peptide receptor and G protein. Inhibition by pertussis toxin-catalyzed ADP ribosylation.
Topics: Adenosine Diphosphate Ribose; Animals; Autoradiography; Brain; Catalysis; Cattle; Centrifugation, Density Gradient; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Pertussis Toxin; Receptors, Formyl Peptide; Receptors, Immunologic; Virulence Factors, Bordetella | 1992 |
Involvement of rho p21 in the GTP-enhanced calcium ion sensitivity of smooth muscle contraction.
Topics: Adenosine Diphosphate Ribose; Animals; Bacterial Proteins; Calcium; Cations, Divalent; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Rabbits; rhoA GTP-Binding Protein; Staphylococcus aureus | 1992 |
Rac1, a low-molecular-mass GTP-binding-protein with high intrinsic GTPase activity and distinct biochemical properties.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Autoradiography; Chromatography, Gel; Complement C3; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Genes, Bacterial; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Hydrolysis; Kinetics; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; rac GTP-Binding Proteins | 1992 |
Properties of 1-methyladenine receptors in starfish oocyte membranes: involvement of pertussis toxin-sensitive GTP-binding protein in the receptor-mediated signal transduction.
Topics: Adenine; Adenosine Diphosphate Ribose; Animals; Cell Membrane; Cholic Acids; Dithiothreitol; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Kinetics; Molecular Weight; NAD; Oocytes; Pertussis Toxin; Proteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Starfish; Virulence Factors, Bordetella | 1992 |
Insulin activates GTP binding to a 40 kDa protein in fat cells.
Topics: Adenosine Diphosphate Ribose; Adipose Tissue; Animals; Cell Membrane; Cholera Toxin; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Insulin; Kinetics; Molecular Weight; Muscles; Protein-Tyrosine Kinases; Receptor, Insulin | 1991 |
Guanine nucleotide-binding protein interacting but unstimulating sequence located in insulin-like growth factor II receptor. Its autoinhibitory characteristics and structural determinants.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclase Inhibitors; Amino Acid Sequence; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Humans; Molecular Sequence Data; Receptors, Cell Surface; Receptors, Somatomedin | 1991 |
Purification and characterization of two G-proteins that activate the beta 1 isozyme of phosphoinositide-specific phospholipase C. Identification as members of the Gq class.
Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Cattle; Chromatography, Liquid; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Isoenzymes; Liver; Magnesium; Pertussis Toxin; Phosphatidylinositols; Type C Phospholipases; Virulence Factors, Bordetella | 1991 |
Modulation of transmembrane signalling in HL-60 granulocytes by tumour necrosis factor-alpha.
Topics: Adenosine Diphosphate Ribose; Dinoprostone; Granulocytes; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Hydrolysis; Immunoblotting; N-Formylmethionine Leucyl-Phenylalanine; Pertussis Toxin; Receptors, Formyl Peptide; Receptors, Immunologic; Signal Transduction; Superoxides; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Virulence Factors, Bordetella | 1991 |
Functional modification by cholera-toxin-catalyzed ADP-ribosylation of a guanine-nucleotide-binding regulatory protein serving as the substrate of pertussis toxin.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Catalysis; Cell Membrane; Cells, Cultured; Cholera Toxin; Electrophoresis, Polyacrylamide Gel; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); N-Formylmethionine; Pertussis Toxin; Receptors, Formyl Peptide; Receptors, Immunologic; Signal Transduction; Substrate Specificity; Trypsin; Virulence Factors, Bordetella | 1991 |
Endothelin receptors and coupled GTP-binding proteins in glomerular mesangial cells.
Topics: Adenosine Diphosphate Ribose; Animals; Endothelins; Enzyme Activation; Fura-2; Glomerular Mesangium; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Kinetics; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Endothelin; Temperature; Type C Phospholipases; Virulence Factors, Bordetella | 1991 |
Expression and purification of functional G protein alpha subunits using a baculovirus expression system.
Topics: Adenosine Diphosphate Ribose; Angiotensin II; Animals; Baculoviridae; Cell Membrane; Cells, Cultured; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Gene Expression; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Liver; Pertussis Toxin; Rats; Receptors, Angiotensin; Virulence Factors, Bordetella | 1992 |
Epoxyeicosatrienoic acid stimulates ADP-ribosylation of a 52 kDa protein in rat liver cytosol.
Topics: 8,11,14-Eicosatrienoic Acid; Adenosine Diphosphate Ribose; Affinity Labels; Animals; Azides; Cholera Toxin; Cytosol; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Kinetics; Liver; Male; Molecular Weight; Pertussis Toxin; Proteins; Rats; Rats, Inbred Strains; Virulence Factors, Bordetella | 1992 |
Purification and characterization of G proteins from human brain: modification of GTPase activity upon phosphorylation.
Topics: Adenosine Diphosphate Ribose; Brain; Cross Reactions; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Humans; Molecular Weight; Pertussis Toxin; Phosphorylation; Protein Kinase C; Protein Kinases; Protein Processing, Post-Translational; Proto-Oncogene Proteins p21(ras); Virulence Factors, Bordetella | 1991 |
Selective loss of pertussis toxin-sensitive G-proteins from the plasma membrane after antibody-induced internalization of T-cell surface molecules.
Topics: Adenosine Diphosphate Ribose; Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Calcium; CD3 Complex; Cell Fractionation; Cell Line; Cell Membrane; Centrifugation, Density Gradient; Cytosol; Exocytosis; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Kinetics; NAD; Pertussis Toxin; Receptors, Antigen, T-Cell; T-Lymphocytes, Cytotoxic; Virulence Factors, Bordetella | 1991 |
A pertussis-toxin-sensitive protein controls exocytosis in chromaffin cells at a step distal to the generation of second messengers.
Topics: Adenosine Diphosphate Ribose; Adrenal Medulla; Animals; Arachidonic Acid; Arachidonic Acids; Bacterial Proteins; Bacterial Toxins; Cattle; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Ethylmaleimide; Exocytosis; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hemolysin Proteins; Kinetics; Nicotine; Norepinephrine; Pertussis Toxin; Potassium; Protein Kinase C; Second Messenger Systems; Staphylococcus aureus; Streptolysins; Veratridine; Virulence Factors, Bordetella | 1991 |
Deletion within the amino-terminal region of Gs alpha impairs its ability to interact with beta gamma subunits and to activate adenylate cyclase.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Cattle; Cell Membrane; Cholera Toxin; DNA Mutational Analysis; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Isoproterenol; Macromolecular Substances; Mice; Peptide Fragments; Receptors, Adrenergic, beta; Recombinant Proteins; Signal Transduction; Structure-Activity Relationship; Trypsin | 1991 |
Evidence for the involvement of a pertussis toxin-insensitive G-protein in egg activation of the frog, Xenopus laevis.
Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Cholera Toxin; Fertilization; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Male; Membrane Potentials; Membrane Proteins; Ovum; Pertussis Toxin; Receptors, Serotonin; Serotonin; Spermatozoa; Virulence Factors, Bordetella; Xenopus laevis | 1991 |
A pertussis toxin-sensitive GTP-binding protein couples endothelin to phospholipase C in rat mesangial cells.
Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Endothelins; Glomerular Mesangium; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Inositol Phosphates; Pertussis Toxin; Rats; Type C Phospholipases; Virulence Factors, Bordetella | 1991 |
Cytosol promotes the guanine nucleotide-induced release of the alpha subunit of Gi2 from the membrane of mouse mastocytoma P-815 cells.
Topics: Adenosine Diphosphate Ribose; Animals; Cell Membrane; Chromatography, Gel; Cytosol; Electrophoresis, Polyacrylamide Gel; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Mast-Cell Sarcoma; Mice; Pertussis Toxin; Substrate Specificity; Thrombin; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1991 |
Receptors for insulin interact with Gi-proteins and for epidermal growth factor with Gi- and Gs-proteins in rat pancreatic acinar cells.
Topics: Adenosine Diphosphate Ribose; Animals; Cell Membrane; Electrophoresis, Polyacrylamide Gel; Epidermal Growth Factor; ErbB Receptors; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Insulin; Membrane Proteins; Molecular Weight; Pancreas; Pertussis Toxin; Phosphorylation; Photochemistry; Rats; Receptor, Insulin; Virulence Factors, Bordetella | 1991 |
Modification of brain guanine nucleotide-binding regulatory proteins by tryptamine-4,5-dione, a neurotoxic derivative of serotonin.
Topics: Adenosine Diphosphate Ribose; Animals; Brain; Catalysis; Ethylmaleimide; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Indolequinones; Neurotoxins; Pertussis Toxin; Serotonin; Tryptamines; Virulence Factors, Bordetella | 1991 |
Signal amplification in HL-60 granulocytes. Evidence that the chemotactic peptide receptor catalytically activates guanine-nucleotide-binding regulatory proteins in native plasma membranes.
Topics: Adenosine Diphosphate Ribose; Cell Membrane; Granulocytes; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Humans; Leukemia, Promyelocytic, Acute; Magnesium; N-Formylmethionine Leucyl-Phenylalanine; Receptors, Formyl Peptide; Receptors, Immunologic; Sodium Chloride; Tumor Cells, Cultured | 1991 |
Quantitation and purification of ADP-ribosylation factor.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; ADP-Ribosylation Factors; Animals; Brain; Cattle; Cell Membrane; Cholera Toxin; Chromatography, Affinity; Chromatography, Gel; Chromatography, Ion Exchange; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Immunoblotting; Indicators and Reagents; Liver; Membrane Proteins; NAD; Phosphorus Radioisotopes; Rabbits; Radioisotope Dilution Technique; Sulfur Radioisotopes | 1991 |
Detection of G proteins in purified bovine brain myelin.
Topics: Adenosine Diphosphate Ribose; Animals; Binding, Competitive; Brain; Cattle; Chemical Fractionation; Chromatography; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Immunoblotting; Myelin Sheath | 1991 |
Phosphorylation of Gi protein by cyclic AMP-dependent protein kinase inhibits its dissociation into alpha-subunits and beta gamma-subunits by Mg2+ and GTP gamma S.
Topics: Adenosine Diphosphate Ribose; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Magnesium; NAD; Pertussis Toxin; Phosphorylation; Protein Conformation; Protein Kinases; Virulence Factors, Bordetella | 1991 |
A blue-light-activated GTP-binding protein in the plasma membranes of etiolated peas.
Topics: Adenosine Diphosphate Ribose; Cell Membrane; Cholera Toxin; Cross Reactions; Darkness; Fabaceae; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Kinetics; Light; Molecular Weight; NAD; Pertussis Toxin; Plants, Medicinal; Virulence Factors, Bordetella | 1991 |
Effect of GTP gamma S on insulin binding and tyrosine phosphorylation in liver membranes and L6 muscle cells.
Topics: Adenosine Diphosphate Ribose; Animals; Cell Line; Cell Membrane; Cell Membrane Permeability; Cholera Toxin; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Insulin; Kinetics; Liver; Male; Muscles; NAD; Phosphorylation; Rats; Rats, Inbred Strains; Receptor, Insulin; Thionucleotides; Tyrosine | 1990 |
Effect of acidosis on PTH-dependent renal adenylate cyclase in phosphorus deprivation: role of G proteins.
Topics: Acidosis; Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Ammonium Chloride; Animals; Cholera Toxin; Colforsin; Dogs; Ethylmaleimide; GTP-Binding Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Kidney; Magnesium; Manganese; Membrane Proteins; Parathyroid Hormone; Pertussis Toxin; Phosphorus; Sodium Fluoride; Thionucleotides; Virulence Factors, Bordetella | 1990 |
Purification and characterization of five different alpha subunits of guanine-nucleotide-binding proteins in bovine brain membranes. Their physiological properties concerning the activities of adenylate cyclase and atrial muscarinic K+ channels.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclase Inhibitors; Animals; Brain; Cattle; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guinea Pigs; Heart Atria; Immunoblotting; Peptide Mapping; Potassium Channels; Receptors, Muscarinic; Thionucleotides | 1990 |
Purification of unique alpha subunits of GTP-binding regulatory proteins (G proteins) by affinity chromatography with immobilized beta gamma subunits.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Animals; Blotting, Western; Brain Chemistry; Cell Membrane; Chromatography, Affinity; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Molecular Sequence Data; Molecular Structure; Peptide Fragments; Pertussis Toxin; Rats; Tissue Distribution; Virulence Factors, Bordetella | 1990 |
The carboxy-terminal domain of Gs alpha is necessary for anchorage of the activated form in the plasma membrane.
Topics: Adenosine Diphosphate Ribose; Cell Membrane; Cell-Free System; Chromosome Deletion; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Membrane Proteins; Molecular Weight; Peptide Fragments; Precipitin Tests; Serine Endopeptidases; Structure-Activity Relationship; Trypsin | 1990 |
Proximal tubular epithelial cells possess a novel 42-kilodalton guanine nucleotide-binding regulatory protein.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Aluminum; Aluminum Compounds; Animals; Cell Membrane; Cholera Toxin; Colforsin; Epithelium; Fluorides; Fluorine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Kidney Tubules, Proximal; Kinetics; Male; Microvilli; Molecular Weight; NAD; Parathyroid Hormone; Pertussis Toxin; Rabbits; Virulence Factors, Bordetella | 1990 |
Muscarinic cholinergic stimulation of inositol phosphate production in cultured embryonic chick atrial cells. Evidence for a role of two guanine-nucleotide-binding proteins.
Topics: Adenosine Diphosphate Ribose; Animals; Atropine; Cells, Cultured; Chick Embryo; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Heart Atria; Inositol Phosphates; Kinetics; Myocardium; NAD; Pertussis Toxin; Receptors, Muscarinic; Type C Phospholipases; Virulence Factors, Bordetella | 1990 |
Light-dependent GTP-binding proteins in squid photoreceptors.
Topics: Adenosine Diphosphate Ribose; Animals; Cell Membrane; Cholera Toxin; Decapodiformes; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Light; Molecular Weight; Pertussis Toxin; Photoreceptor Cells; Protein Binding; Virulence Factors, Bordetella | 1990 |
The G protein coupling T cell antigen receptor/CD3-complex and phospholipase C in the human T cell lymphoma Jurkat is not a target for cholera toxin.
Topics: Adenosine Diphosphate Ribose; Antibodies, Monoclonal; Antigens, Differentiation, T-Lymphocyte; CD3 Complex; Cholera Toxin; Colforsin; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Inositol Phosphates; Lymphoma, T-Cell; Receptors, Antigen, T-Cell; Tumor Cells, Cultured; Type C Phospholipases | 1990 |
Thrombin stimulates inositol phosphate production and intracellular free calcium by a pertussis toxin-insensitive mechanism in osteosarcoma cells.
Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Cricetinae; Fibroblasts; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Inositol; Inositol Phosphates; Kinetics; Osteosarcoma; Pertussis Toxin; Phosphoinositide Phospholipase C; Phosphoric Diester Hydrolases; Rats; Signal Transduction; Thionucleotides; Thrombin; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1990 |
Functional and immunological evidence for stable association of solubilized vasoactive-intestinal-peptide receptor and stimulatory guanine-nucleotide-binding protein from rat liver.
Topics: Adenosine Diphosphate Ribose; Animals; Autoradiography; Binding Sites; Chromatography, Affinity; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Immunoblotting; Liver; Rats; Receptors, Gastrointestinal Hormone; Receptors, Vasoactive Intestinal Peptide; Sepharose; Solubility; Thionucleotides; Vasoactive Intestinal Peptide | 1990 |
Cholera toxin modulation of angiotensin II-stimulated inositol phosphate production in cultured vascular smooth muscle cells.
Topics: Adenosine Diphosphate Ribose; Angiotensin II; Animals; Bucladesine; Calcium; Cells, Cultured; Cholera Toxin; Depression, Chemical; Electrophoresis, Polyacrylamide Gel; Endothelium, Vascular; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Inositol 1,4,5-Trisphosphate; Rats; Receptors, Angiotensin; Sodium Fluoride; Thionucleotides | 1990 |
The epidermal growth factor receptor is coupled to a phospholipase A2-specific pertussis toxin-inhibitable guanine nucleotide-binding regulatory protein in cultured rat inner medullary collecting tubule cells.
Topics: Adenosine Diphosphate Ribose; Aluminum; Aluminum Compounds; Animals; Calcium; Cells, Cultured; Dinoprostone; Epidermal Growth Factor; ErbB Receptors; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Kidney Medulla; Kidney Tubules; Kidney Tubules, Collecting; Kinetics; Pertussis Toxin; Phosphatidylinositols; Phospholipases; Phospholipases A; Phospholipases A2; Rats; Tetradecanoylphorbol Acetate; Thionucleotides; Virulence Factors, Bordetella | 1990 |
Monoclonal anti-CD23 antibodies induce a rise in [Ca2+]i and polyphosphoinositide hydrolysis in human activated B cells. Involvement of a Gp protein.
Topics: Adenosine Diphosphate Ribose; Antibodies, Monoclonal; Antigens, Differentiation, B-Lymphocyte; B-Lymphocytes; Calcium; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; In Vitro Techniques; Inositol Phosphates; Lymphocyte Activation; Pertussis Toxin; Phosphatidylinositols; Receptors, Fc; Receptors, IgE; Signal Transduction; Thionucleotides; Virulence Factors, Bordetella | 1990 |
Possible interaction of alpha 1-adrenergic receptor with pertussis-toxin-sensitive guanine-nucleotide-binding regulatory proteins (G proteins) responsible for phospholipase C activation in rat liver plasma membranes.
Topics: Adenosine Diphosphate Ribose; Animals; Cell Membrane; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Inositol 1,4,5-Trisphosphate; Liver; Pertussis Toxin; Prazosin; Rats; Receptors, Adrenergic, alpha; Type C Phospholipases; Virulence Factors, Bordetella; Yohimbine | 1990 |
Reduction of adenylyl cyclase activity by cholera toxin in myeloid cells. Long-term down-regulation of Gs alpha subunits by cholera toxin treatment.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Cell Communication; Cholera Toxin; Drug Resistance; Enzyme Activation; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Immunoblotting; Leukemia, Myeloid, Acute; Membrane Proteins; Pertussis Toxin; Rats; Thionucleotides; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1990 |
Conformations of the alpha 39, alpha 41, and beta.gamma components of brain guanine nucleotide-binding proteins. Analysis by limited proteolysis.
Topics: Adenosine Diphosphate Ribose; Animals; Cattle; Cerebral Cortex; Epitopes; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Pertussis Toxin; Phosphorus Radioisotopes; Protein Conformation; Rabbits; Thionucleotides; Trypsin; Virulence Factors, Bordetella | 1986 |
Myelin basic protein binds GTP at a single site in the N-terminus.
Topics: Adenosine Diphosphate Ribose; Amino Acids; Azides; Binding Sites; Cholera Toxin; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; Myelin Basic Protein; Pertussis Toxin; Thionucleotides; Virulence Factors, Bordetella | 1988 |
Patch-clamp capacitance measurements: a tool for investigating the second messengers regulating exocytosis.
Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Cell Membrane; Exocytosis; Fluorescent Dyes; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Heparin; Histamine Release; Immunoglobulin M; Mast Cells; Peritoneal Cavity; Rats; Receptors, Fc; Second Messenger Systems; Thionucleotides | 1989 |
Angiotensin II receptors negatively coupled to adenylate cyclase in rat myocardial sarcolemma. Involvement of inhibitory guanine nucleotide regulatory protein.
Topics: Acrosin; Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Angiotensin II; Animals; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Male; Myocardium; Pertussis Toxin; Rabbits; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Sarcolemma; Serine Endopeptidases; Thionucleotides; Virulence Factors, Bordetella | 1989 |
An endogenous inhibitor of the ADP-ribosylation of GTP-binding proteins by pertussis toxin is present in bovine brain.
Topics: Adenosine Diphosphate Ribose; Animals; Brain Chemistry; Catalysis; Cattle; Chromatography; Drug Stability; Freezing; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hot Temperature; Pertussis Toxin; Thionucleotides; Virulence Factors, Bordetella | 1989 |
Identification of rho as a substrate for botulinum toxin C3-catalyzed ADP-ribosylation.
Topics: Adenosine Diphosphate Ribose; Animals; Antibodies, Monoclonal; Aplysia; Botulinum Toxins; Cattle; Cell Membrane; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Hydrolysis; Kinetics; Membrane Proteins; Molecular Weight; Neutrophils; Recombinant Proteins; rhoB GTP-Binding Protein; Thionucleotides | 1989 |
Reconstitution of cyc- S49 membranes by in vitro translated Gs alpha. Membrane anchorage and functional implications.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Cell Membrane; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Hydrogen-Ion Concentration; Isoproterenol; Lymphoma; Mice; Molecular Weight; Mutation; NAD; Osmolar Concentration; Protein Biosynthesis; RNA, Messenger; Thionucleotides; Tumor Cells, Cultured | 1989 |
Involvement of a specific guanine nucleotide binding protein in receptor immunoglobulin stimulated inositol phospholipid hydrolysis.
Topics: Adenosine Diphosphate Ribose; Animals; B-Lymphocytes; Cell Membrane; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Hydrolysis; Immunoglobulin M; Immunoglobulin mu-Chains; Lymphoma; Mice; Pertussis Toxin; Phosphatidylinositols; Receptors, Immunologic; Thionucleotides; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1989 |
Trypanosoma cruzi: infection of cultured human endothelial cells alters inositol phosphate synthesis.
Topics: Adenosine Diphosphate Ribose; Animals; Bradykinin; Calcium; Cells, Cultured; Cholera Toxin; Endothelium, Vascular; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Inositol Phosphates; Kinetics; Pertussis Toxin; Signal Transduction; Thionucleotides; Trypanosoma cruzi; Umbilical Veins; Virulence Factors, Bordetella | 1989 |
Immunological and molecular characterization of Go alpha-like proteins in the Drosophila central nervous system.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Animals; Base Sequence; Blotting, Western; Chromosome Mapping; DNA; DNA Probes; Drosophila melanogaster; Gene Expression; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Immunosorbent Techniques; Molecular Sequence Data; Nervous System; Nucleic Acid Hybridization; Pertussis Toxin; Sequence Homology, Nucleic Acid; Thionucleotides; Virulence Factors, Bordetella | 1989 |
Olfactory adenylyl cyclase. Identification and purification of a novel enzyme form.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Antibodies, Monoclonal; Blotting, Western; Brain; Calcium; Calmodulin; Chromatography, Affinity; Cilia; Colforsin; Epithelium; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Molecular Weight; Olfactory Mucosa; Rats; Rats, Inbred Strains; Thionucleotides | 1989 |
G-protein dependent potentiation of calcium release from sarcoplasmic reticulum of skeletal muscle.
Topics: Adenosine Diphosphate Ribose; Animals; Caffeine; Calcium; Cattle; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Immunoblotting; In Vitro Techniques; Muscle Contraction; Muscles; Pertussis Toxin; Rana esculenta; Rats; Sarcoplasmic Reticulum; Subcellular Fractions; Thionucleotides; Transducin; Virulence Factors, Bordetella | 1989 |
Properties of membranous phospholipase C from WRK1 cell: sensitivity to guanylnucleotides and bacterial toxins.
Topics: Adenosine Diphosphate Ribose; Calcium; Cell Fractionation; Cell Membrane; Cells, Cultured; Cholera Toxin; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Inositol Phosphates; Pertussis Toxin; Receptors, Angiotensin; Receptors, Vasopressin; Thionucleotides; Type C Phospholipases; Vasopressins; Virulence Factors, Bordetella | 1989 |
Ontogenesis of alpha 2-adrenoceptor coupling with GTP-binding proteins in the rat telencephalon.
Topics: Adenosine Diphosphate Ribose; Animals; Animals, Newborn; Chlorides; Cholera Toxin; Clonidine; Fetus; GTP-Binding Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Immunoblotting; Manganese; Manganese Compounds; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Telencephalon; Thionucleotides; Tissue Extracts; Virulence Factors, Bordetella | 1989 |
Guanine nucleotides stimulate hydrolysis of phosphatidyl inositol bis phosphate in human myelin membranes.
Topics: Adenosine Diphosphate Ribose; Aluminum; Aluminum Compounds; Cell Membrane; Fluorides; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Hydrolysis; Myelin Proteins; Myelin Sheath; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Diacylglycerol-Lyase; Phosphatidylinositols; Phosphoric Diester Hydrolases; Thionucleotides; Tritium | 1989 |
Regulation of signal transfer from beta 1-adrenoceptor to adenylate cyclase by beta gamma subunits in a reconstituted system.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Brain; Cattle; Erythrocyte Membrane; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Homeostasis; Kinetics; Pertussis Toxin; Photoreceptor Cells; Receptors, Adrenergic, beta; Rod Cell Outer Segment; Thionucleotides; Turkeys; Virulence Factors, Bordetella | 1987 |
Cholera toxin and pertussis toxin stimulate prostaglandin E2 synthesis in a murine macrophage cell line.
Topics: Adenosine Diphosphate Ribose; Animals; Arachidonic Acid; Arachidonic Acids; Cell Line; Cholera Toxin; Cyclic AMP; Dinoprostone; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Macrophages; Membrane Proteins; Mice; Molecular Weight; Pertussis Toxin; Phospholipases A; Phospholipases A2; Prostaglandins E; Thionucleotides; Virulence Factors, Bordetella | 1988 |
Properties of a novel GTP-binding protein which is associated with soluble phosphoinositides-specific phospholipase C.
Topics: Adenosine Diphosphate Ribose; Animals; Cattle; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hydrolysis; Kinetics; Molecular Weight; Phosphatidylinositols; Substrate Specificity; Thionucleotides; Thymus Gland; Type C Phospholipases | 1988 |
Effect of tumor necrosis factor on GTP binding and GTPase activity in HL-60 and L929 cells.
Topics: Adenosine Diphosphate Ribose; Animals; Cell Line; Cell Membrane; Cyclic AMP; GTP Phosphohydrolases; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Kinetics; L Cells; Leukemia, Myeloid, Acute; Mice; Pertussis Toxin; Phosphoric Monoester Hydrolases; Receptors, Cell Surface; Receptors, Tumor Necrosis Factor; Thionucleotides; Tumor Necrosis Factor-alpha; Virulence Factors, Bordetella | 1988 |
Partial characterization of GTP-binding proteins in Neurospora.
Topics: Adenosine Diphosphate Ribose; Cell Membrane; Chromatography, Gel; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Kinetics; Neurospora; Neurospora crassa; Sulfur Radioisotopes; Thionucleotides | 1987 |
Uncoupling of gamma-aminobutyric acid B receptors from GTP-binding proteins by N-ethylmaleimide: effect of N-ethylmaleimide on purified GTP-binding proteins.
Topics: Adenosine Diphosphate Ribose; Animals; Cattle; Ethylmaleimide; gamma-Aminobutyric Acid; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; In Vitro Techniques; Magnesium; Pertussis Toxin; Receptors, GABA-A; Thionucleotides; Tritium; Virulence Factors, Bordetella | 1986 |
Coupling of the thyrotropin-releasing hormone receptor to phospholipase C by a GTP-binding protein distinct from the inhibitory or stimulatory GTP-binding protein.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cell Line; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Pertussis Toxin; Pituitary Neoplasms; Prolactin; Rats; Receptors, Cell Surface; Receptors, Thyrotropin-Releasing Hormone; Thionucleotides; Thyrotropin-Releasing Hormone; Type C Phospholipases; Virulence Factors, Bordetella | 1986 |
Effect of pertussis toxin on the phosphodiesteratic cleavage of the polyphosphoinositides by guanosine 5'-O-thiotriphosphate and thrombin in permeabilized human platelets.
Topics: Adenosine Diphosphate Ribose; Blood Platelets; Calcium; Cell Membrane Permeability; Enzyme Activation; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Hydrolysis; Pertussis Toxin; Phosphatidylinositol Phosphates; Phosphatidylinositols; Saponins; Thionucleotides; Thrombin; Type C Phospholipases; Virulence Factors, Bordetella | 1986 |
Subunit interactions of native and ADP-ribosylated alpha 39 and alpha 41, two guanine nucleotide-binding proteins from bovine cerebral cortex.
Topics: Adenosine Diphosphate Ribose; Animals; Cattle; Cerebral Cortex; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Immunosorbent Techniques; Nucleoside Diphosphate Sugars; Thionucleotides | 1986 |
Phorbol ester treatment impairs hormone- but not stable GTP analog-induced inhibition of adenylate cyclase.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclase Inhibitors; Blood Platelets; Epinephrine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Hydrolysis; Lymphoma; Phorbols; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Thionucleotides | 1986 |
Mechanisms for inhibition of the catalytic activity of adenylate cyclase by the guanine nucleotide-binding proteins serving as the substrate of islet-activating protein, pertussis toxin.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Brain Chemistry; Colforsin; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Liver; Pertussis Toxin; Rabbits; Rats; Thionucleotides; Virulence Factors, Bordetella | 1986 |
The protein cofactor necessary for ADP-ribosylation of Gs by cholera toxin is itself a GTP binding protein.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Binding, Competitive; Brain; Cattle; Cell Membrane; Cholera Toxin; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Kinetics; Nucleoside Diphosphate Sugars; Thionucleotides | 1986 |
Two guanine nucleotide-binding proteins in rat brain serving as the specific substrate of islet-activating protein, pertussis toxin. Interaction of the alpha-subunits with beta gamma-subunits in development of their biological activities.
Topics: Adenosine Diphosphate Ribose; Animals; Brain Chemistry; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Macromolecular Substances; Magnesium; Magnesium Chloride; Molecular Weight; Pertussis Toxin; Rats; Thionucleotides; Virulence Factors, Bordetella | 1986 |
Spermatozoa contain a guanine nucleotide-binding protein ADP-ribosylated by pertussis toxin.
Topics: Adenosine Diphosphate Ribose; Animals; Cattle; Cell Membrane; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guinea Pigs; Male; Nucleoside Diphosphate Sugars; Pertussis Toxin; Phosphorus Radioisotopes; Sea Urchins; Species Specificity; Spermatozoa; Sulfur Radioisotopes; Swine; Thionucleotides; Virulence Factors, Bordetella | 1986 |
Guanine nucleotide-binding protein in sea urchin eggs serving as the specific substrate of islet-activating protein, pertussis toxin.
Topics: Adenosine Diphosphate Ribose; Animals; Cross Reactions; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Magnesium; Ovum; Pertussis Toxin; Sea Urchins; Thionucleotides; Virulence Factors, Bordetella | 1986 |
Evidence for the role of a guanine nucleotide-binding regulatory protein in the zona pellucida-induced mouse sperm acrosome reaction.
Topics: Acrosome; Adenosine Diphosphate Ribose; Animals; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Male; Mice; Ovum; Sperm Capacitation; Sperm-Ovum Interactions; Spermatozoa; Thionucleotides; Zona Pellucida | 1987 |
Purification and immunochemical characterization of the major pertussis-toxin-sensitive guanine-nucleotide-binding protein of bovine-neutrophil membranes.
Topics: Adenosine Diphosphate Ribose; Animals; Cattle; Cell Fractionation; Cell Membrane; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Immunoenzyme Techniques; Macromolecular Substances; Molecular Weight; Neutrophils; Pertussis Toxin; Thionucleotides; Virulence Factors, Bordetella | 1987 |
ADP-ribosylation of specific membrane proteins in pheochromocytoma and primary-cultured brain cells by botulinum neurotoxins type C and D.
Topics: Adenosine Diphosphate Ribose; Botulinum Toxins; Brain; Cells, Cultured; Clostridium botulinum; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Magnesium; Magnesium Chloride; Membrane Proteins; Molecular Weight; Nerve Tissue Proteins; Neurotoxins; Pheochromocytoma; Thionucleotides | 1987 |
Guanosine 5'-O-(3-thiotriphosphate) reduces ADP-ribosylation of the inhibitory guanine nucleotide-binding regulatory protein of adenylyl cyclase (Ni) by pertussis toxin without causing dissociation of the subunits of Ni. Evidence of existence of heterotri
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; ADP Ribose Transferases; Cations, Divalent; Edetic Acid; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Macromolecular Substances; Magnesium; Pentosyltransferases; Pertussis Toxin; Protein Conformation; Thionucleotides; Virulence Factors, Bordetella | 1987 |
Expression of cDNAs for G proteins in Escherichia coli. Two forms of Gs alpha stimulate adenylate cyclase.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Brain Chemistry; Cattle; Centrifugation, Density Gradient; Cholera Toxin; Chromatography; DNA; DNA-Directed RNA Polymerases; DNA, Recombinant; Escherichia coli; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Plasmids; T-Phages; Thionucleotides; Transformation, Genetic | 1987 |
GTP-binding proteins in etiolated epicotyls of Pisum sativum (Alaska) seedlings.
Topics: Adenosine Diphosphate Ribose; Chromatography, Gel; Fabaceae; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Kinetics; Pertussis Toxin; Plants; Plants, Medicinal; Protein Binding; Thionucleotides; Virulence Factors, Bordetella | 1987 |
Receptor-mediated ADP-ribosylation of a phospholipase C-stimulating G protein.
Topics: Adenosine Diphosphate Ribose; Cell Differentiation; Cholera Toxin; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Leukemia, Myeloid, Acute; Male; N-Formylmethionine Leucyl-Phenylalanine; Neoplasm Proteins; Pertussis Toxin; Receptors, Formyl Peptide; Receptors, Immunologic; Thionucleotides; Tumor Cells, Cultured; Type C Phospholipases; Virulence Factors, Bordetella | 1987 |
ADP-ribosylation of a 21-24 kDa eukaryotic protein(s) by C3, a novel botulinum ADP-ribosyltransferase, is regulated by guanine nucleotide.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Blood Platelets; Blood Proteins; Cell Membrane; Clostridium botulinum; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; Membrane Proteins; Pentosyltransferases; Thionucleotides; Toxoids | 1987 |
Stimulation of choleragen enzymatic activities by GTP and two soluble proteins purified from bovine brain.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; ADP Ribose Transferases; Animals; Brain Chemistry; Cattle; Cholera Toxin; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Molecular Weight; Nerve Tissue Proteins; Pentosyltransferases; Thionucleotides | 1988 |
Reconstitution of the purified porcine atrial muscarinic acetylcholine receptor with purified porcine atrial inhibitory guanine nucleotide binding protein.
Topics: Adenosine Diphosphate Ribose; Animals; Carbachol; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Heart Atria; Kinetics; Mathematics; Myocardium; Receptors, Muscarinic; Swine; Thionucleotides | 1987 |
Acetylcholine and cholecystokinin receptors functionally couple by different G-proteins to phospholipase C in pancreatic acinar cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Diphosphate Ribose; Animals; Carbachol; Cholera Toxin; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Male; Pancreas; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin; Receptors, Cholinergic; Sincalide; Thionucleotides; Type C Phospholipases; Vasoactive Intestinal Peptide | 1988 |
Mastoparan, a peptide toxin from wasp venom, mimics receptors by activating GTP-binding regulatory proteins (G proteins).
Topics: Adenosine Diphosphate Ribose; Animals; Bee Venoms; Brain; Cattle; Cell Membrane; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Intercellular Signaling Peptides and Proteins; Kinetics; Liver; Peptides; Pertussis Toxin; Rabbits; Receptors, Drug; Thionucleotides; Virulence Factors, Bordetella; Wasp Venoms | 1988 |
GTP-binding proteins and adenylate cyclase activity in v-Ki-ras transformed NIH/3T3 fibroblast cells.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Cell Line; Cell Transformation, Neoplastic; Fibroblasts; Genes, ras; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Kinetics; Mice; Molecular Weight; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Thionucleotides | 1988 |
Subcellular localization of Gi alpha in human neutrophils.
Topics: Adenosine Diphosphate Ribose; Cell Fractionation; Centrifugation, Density Gradient; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Subcellular Fractions; Thionucleotides; Virulence Factors, Bordetella | 1988 |
GTP binding regulatory proteins of adenylate cyclase in Schistosoma mansoni at different stages of development.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cholera Toxin; Colforsin; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Membranes; Pertussis Toxin; Schistosoma mansoni; Serotonin; Sodium Fluoride; Thionucleotides; Virulence Factors, Bordetella | 1988 |
Purification and properties of the cytosolic substrate for botulinum ADP-ribosyltransferase. Identification as an Mr 22,000 guanine nucleotide-binding protein.
Topics: Adenosine Diphosphate Ribose; Adrenal Glands; Animals; Binding, Competitive; Cattle; Chromatography; Chromatography, High Pressure Liquid; Clostridium botulinum; Cytosol; Electrophoresis, Polyacrylamide Gel; Fractional Precipitation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Male; NAD; Poly(ADP-ribose) Polymerases; Rats; Rats, Inbred Strains; Thionucleotides; Tissue Distribution | 1988 |
ADP-ribosylation of the bovine brain rho protein by botulinum toxin type C1.
Topics: Adenosine Diphosphate Ribose; Animals; Botulinum Toxins; Cattle; Cell Membrane; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Magnesium; Membrane Proteins; rhoB GTP-Binding Protein; Thionucleotides | 1988 |
Identification of a G protein in rough endoplasmic reticulum of canine pancreas.
Topics: Adenosine Diphosphate Ribose; Animals; Dogs; Endoplasmic Reticulum; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Kinetics; Microsomes; Molecular Weight; Pancreas; Pertussis Toxin; Reference Values; Sodium Fluoride; Thionucleotides; Virulence Factors, Bordetella | 1988 |
Characterization of transducin from bovine retinal rod outer segments. Participation of the amino-terminal region of T alpha in subunit interaction.
Topics: Adenosine Diphosphate Ribose; Animals; Antibodies, Monoclonal; Binding Sites; Cattle; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Macromolecular Substances; Membrane Proteins; Metalloendopeptidases; Pertussis Toxin; Photoreceptor Cells; Rod Cell Outer Segment; Thionucleotides; Transducin; Virulence Factors, Bordetella | 1987 |
ADP-ribosylation by cholera toxin: functional analysis of a cellular system that stimulates the enzymic activity of cholera toxin fragment A1.
Topics: Adenosine Diphosphate Ribose; Animals; Cattle; Cholera Toxin; Erythrocyte Membrane; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Kinetics; Male; Peptide Fragments; Proteins; Testis; Thionucleotides | 1987 |
Characteristics of the guanine nucleotide-binding regulatory component of adenylate cyclase.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Blood Proteins; Cell Membrane; Enzyme Activation; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Mathematics; Receptors, Cell Surface; Thionucleotides | 1982 |
A second guanyl nucleotide-binding site associated with adenylate cyclase. Distinct nucleotides activate adenylate cyclase and permit ADP-ribosylation by cholera toxin.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Cholera Toxin; Columbidae; Cytosol; Erythrocytes; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Kinetics; Nucleoside Diphosphate Sugars; Receptors, Cell Surface; Thionucleotides | 1983 |
Purification and properties of the inhibitory guanine nucleotide-binding regulatory component of adenylate cyclase.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Binding, Competitive; Cell Membrane; GTP-Binding Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Kinetics; Liver; Molecular Weight; Protein Binding; Rabbits; Receptors, Cell Surface; Thionucleotides | 1984 |
The inhibitory guanine nucleotide-binding regulatory component of adenylate cyclase. Subunit dissociation and guanine nucleotide-dependent hormonal inhibition.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Blood Platelets; Cell Membrane; Epinephrine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Kinetics; Macromolecular Substances; Molecular Weight; Receptors, Cell Surface; Thionucleotides | 1984 |
Pertussis toxin catalyzes the ADP-ribosylation of two distinct peptides, 40 and 41 kDa, in rat fat cell membranes.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adipose Tissue; Animals; Bacterial Toxins; Cholera Toxin; Electrophoresis, Polyacrylamide Gel; Female; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Liver; Lymphoma; Membrane Proteins; Molecular Weight; NAD; Nucleoside Diphosphate Sugars; Peptide Hydrolases; Pertussis Toxin; Rats; Rats, Inbred Strains; Thionucleotides; Virulence Factors, Bordetella | 1984 |
Isolation of two proteins with high affinity for guanine nucleotides from membranes of bovine brain.
Topics: Adenosine Diphosphate Ribose; Animals; Brain Chemistry; Cattle; Chromatography, Affinity; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Liver; Rabbits; Rod Cell Outer Segment; Thionucleotides; Trypsin | 1984 |
Cyclic ADP-ribose regulation of ryanodine receptors involved in agonist evoked cytosolic Ca2+ oscillations in pancreatic acinar cells.
Topics: Acetylcholine; Adenosine Diphosphate Ribose; Caffeine; Calcium; Calcium Channels; Cholecystokinin; Cyclic ADP-Ribose; Cytosol; Evoked Potentials; Guanosine 5'-O-(3-Thiotriphosphate); Heparin; Inositol 1,4,5-Trisphosphate; Muscle Proteins; Pancreas; Ruthenium Red; Ryanodine; Ryanodine Receptor Calcium Release Channel | 1994 |
Whole-cell clamp analysis for G-protein regulation of channels.
Topics: Adenosine Diphosphate Ribose; Animals; Calcium Channels; Carbachol; Cholera Toxin; Electrophysiology; Epinephrine; Glioma; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanylyl Imidodiphosphate; Homeostasis; Hybrid Cells; Ion Channels; Macromolecular Substances; Neuroblastoma; Oligonucleotides, Antisense; Patch-Clamp Techniques; PC12 Cells; Potassium Channels; Rats; RNA, Messenger; Virulence Factors, Bordetella | 1994 |
Effect of PT-treatment on ANP-mediated inhibition of adenylate cyclase and amylase release in rat parotid gland.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Amylases; Animals; Atrial Natriuretic Factor; Colforsin; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Isoproterenol; Male; Parotid Gland; Pertussis Toxin; Rats; Rats, Wistar; Receptors, Atrial Natriuretic Factor; Virulence Factors, Bordetella | 1994 |
Activation of a G protein complex by aggregation of beta-1,4-galactosyltransferase on the surface of sperm.
Topics: Acrosome; Adenosine Diphosphate Ribose; Amino Acid Sequence; Animals; Cell Membrane; Egg Proteins; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Ligands; Male; Membrane Glycoproteins; Mice; Mice, Transgenic; Molecular Sequence Data; N-Acetyllactosamine Synthase; Peptide Fragments; Pertussis Toxin; Receptors, Cell Surface; Signal Transduction; Spermatozoa; Virulence Factors, Bordetella; Zona Pellucida; Zona Pellucida Glycoproteins | 1995 |
Involvement of heterotrimeric GTP-binding protein and rho protein, but not protein kinase C, in agonist-induced Ca2+ sensitization of skinned muscle of guinea pig vas deferens.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Aluminum Compounds; Animals; Botulinum Toxins; Calcium; Escin; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Peptides; Phorbol 12,13-Dibutyrate; Protein Kinase C; rho GTP-Binding Proteins; Vas Deferens | 1995 |
Functional expression of the taste specific G-protein, alpha-gustducin.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine Diphosphate Ribose; Animals; Baculoviridae; Base Sequence; Catalysis; Cell Line; Cloning, Molecular; DNA Primers; DNA, Complementary; Enzyme Activation; GTP Phosphohydrolases; Guanosine 5'-O-(3-Thiotriphosphate); Molecular Sequence Data; Protein Binding; Recombinant Proteins; Rhodopsin; Spodoptera; Taste; Transducin; Virulence Factors, Bordetella | 1995 |
Coupling of a single receptor to two different G proteins in the signal transduction of FMRFamide-related peptides.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Animals; Cholera Toxin; Female; FMRFamide; Grasshoppers; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Molecular Sequence Data; Neuropeptides; Neurotransmitter Agents; Receptors, Neuropeptide; Signal Transduction; Virulence Factors, Bordetella | 1995 |
Myristoylation and ADP-ribosylation factor function.
Topics: Acyltransferases; Adenosine Diphosphate Ribose; ADP-Ribosylation Factors; Amino Acid Sequence; Animals; Autoradiography; Binding Sites; Brain; Carrier Proteins; Cattle; Chromatography, Gel; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Cloning, Molecular; Electrophoresis, Polyacrylamide Gel; Escherichia coli; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Molecular Sequence Data; Molecular Weight; Myristic Acid; Myristic Acids; Protein Processing, Post-Translational; Recombinant Proteins; Saccharomyces cerevisiae; Substrate Specificity; Tritium | 1995 |
G-proteins in rat blood vessels--I. Identification.
Topics: Adenosine Diphosphate Ribose; Animals; Aorta; Blotting, Western; Cholera Toxin; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Male; Mesenteric Arteries; Molecular Weight; Pertussis Toxin; Rats; Rats, Wistar; Virulence Factors, Bordetella | 1995 |
G protein-coupled corticotropin-releasing hormone receptors in rat retina.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Amphibian Proteins; Animals; Binding Sites; Binding, Competitive; Cholera Toxin; Corticotropin-Releasing Hormone; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Kinetics; Male; Peptide Hormones; Peptides; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Retina; Urotensins | 1995 |
Altered guanine nucleoside triphosphate binding to transducin by cholera toxin-catalysed ADP-ribosylation.
Topics: Adenosine Diphosphate Ribose; Animals; Binding Sites; Cattle; Cell Membrane; Cholera Toxin; GTP Phosphohydrolases; Guanosine 5'-O-(3-Thiotriphosphate); Light; Pertussis Toxin; Rod Cell Outer Segment; Transducin; Virulence Factors, Bordetella | 1994 |
Sequestration of a G-protein beta gamma subunit or ADP-ribosylation of Rho can inhibit thrombin-induced activation of platelet phosphoinositide 3-kinases.
Topics: Adenosine Diphosphate Ribose; Animals; Blood Platelets; Cattle; Cytoskeleton; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Membrane Proteins; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); rhoB GTP-Binding Protein; Thrombin | 1995 |
Regulation of renal cortical Na-HCO3 cotransporter. II. Role of G proteins.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Animals; Bicarbonates; Biological Transport, Active; Carrier Proteins; Cholera Toxin; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Kidney Cortex; Pertussis Toxin; Protein Conformation; Rabbits; Sodium; Sodium-Bicarbonate Symporters; Virulence Factors, Bordetella | 1995 |
Activation of rat liver phospholipase D by the small GTP-binding protein RhoA.
Topics: Adenosine Diphosphate Ribose; Animals; Enzyme Activation; GTP-Binding Proteins; Guanine Nucleotide Dissociation Inhibitors; Guanosine 5'-O-(3-Thiotriphosphate); Liver; Male; Phospholipase D; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; rho-Specific Guanine Nucleotide Dissociation Inhibitors; rhoA GTP-Binding Protein | 1994 |
Purification and separation of closely related members of pertussis toxin-substrate G proteins.
Topics: Adenosine Diphosphate Ribose; Animals; Binding Sites; Cattle; Cell Membrane; Cerebral Cortex; Chromatography, Ion Exchange; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Macromolecular Substances; NAD; Pertussis Toxin; Phosphorus Radioisotopes; Protein Binding; Radioisotope Dilution Technique; Sulfur Radioisotopes; Virulence Factors, Bordetella | 1994 |
Synthesis and use of radioactive photoactivatable NAD+ derivatives as probes for G-protein structure.
Topics: Adenosine Diphosphate Ribose; Affinity Labels; Animals; Cattle; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Iodine Radioisotopes; Kinetics; Macromolecular Substances; NAD; Peptide Fragments; Phosphorus Radioisotopes; Radioisotope Dilution Technique; Rod Cell Outer Segment; Structure-Activity Relationship; Sulfur Radioisotopes; Transducin; Trypsin | 1994 |
Isolation and purification of a small-molecular-weight GTP-binding protein from plants.
Topics: Adenosine Diphosphate Ribose; Avena; Binding, Competitive; Cholera Toxin; Chromatography, Affinity; Cross Reactions; Darkness; Ethylmaleimide; GTP Phosphohydrolases; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Molecular Weight; ras Proteins; Sepharose; Signal Transduction | 1994 |
Mastoparan may activate GTP hydrolysis by Gi-proteins in HL-60 membranes indirectly through interaction with nucleoside diphosphate kinase.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphatases; Amino Acid Sequence; Animals; Calcium; Cattle; Cell Membrane; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Hydrolysis; Intercellular Signaling Peptides and Proteins; Mitochondria, Liver; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Nucleoside-Diphosphate Kinase; Peptides; Pertussis Toxin; Superoxides; Tumor Cells, Cultured; Virulence Factors, Bordetella; Wasp Venoms | 1994 |
Characterization of GTP-binding proteins coupled to inhibition of adenylyl cyclase in guinea pig tracheal epithelial cells.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Atropine; Carbachol; Cell Membrane; Cells, Cultured; Cholera Toxin; Cyclic AMP; Epithelial Cells; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guinea Pigs; Kinetics; Male; Pertussis Toxin; Receptors, Muscarinic; Sodium Fluoride; Specific Pathogen-Free Organisms; Trachea; Virulence Factors, Bordetella | 1994 |
Guanine nucleotides and pertussis toxin reduce the affinity of histamine H3 receptors on AtT-20 cells.
Topics: Adenosine Diphosphate Ribose; Animals; Cell Line; Cell Membrane; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Histamine Agonists; Methylhistamines; Mice; NAD; Pertussis Toxin; Phosphorus Radioisotopes; Pituitary Gland; Receptors, Histamine H3; Signal Transduction; Virulence Factors, Bordetella | 1993 |
G-proteins coupled to phosphoinositide hydrolysis in the cochlear and vestibular sensory epithelia of the rat are insensitive to cholera and pertussis toxins.
Topics: Adenosine Diphosphate Ribose; Aluminum Chloride; Aluminum Compounds; Animals; Chlorides; Cholera Toxin; Cochlea; Drug Resistance; Epithelium; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Hydrolysis; Male; Pertussis Toxin; Phosphatidylinositols; Rats; Rats, Inbred F344; Sodium Fluoride; Thionucleotides; Vestibule, Labyrinth; Virulence Factors, Bordetella | 1994 |
Differential expression of guanosine triphosphate binding proteins in men at high and low risk for the future development of alcoholism.
Topics: Adenosine Diphosphate Ribose; Adult; Alcoholism; Cell Membrane; Erythrocyte Membrane; Family; Fathers; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Immunoblotting; Isoproterenol; Kinetics; Lymphocytes; Male; Regression Analysis; Risk Factors | 1994 |
Somatostatin induces release of the alpha subunits of pertussis toxin-sensitive G proteins in native membranes and in intact GH4C1 rat pituitary cells.
Topics: Adenosine Diphosphate Ribose; Animals; Cell Membrane; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Pertussis Toxin; Pituitary Gland, Anterior; Rats; Receptors, Somatostatin; Signal Transduction; Somatostatin; Thionucleotides; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1993 |
Effects of carboxyl methylation of photoreceptor G protein gamma-subunit in visual transduction.
Topics: Adenosine Diphosphate Ribose; Animals; Cattle; Chromatography, Gel; Darkness; Farnesol; Guanosine 5'-O-(3-Thiotriphosphate); Intracellular Membranes; Kinetics; Light; Macromolecular Substances; Methylation; Microsomes; Protein Prenylation; Protein Processing, Post-Translational; Rana catesbeiana; Rhodopsin; Rod Cell Outer Segment; Signal Transduction; Transducin; Virulence Factors, Bordetella; Vision, Ocular | 1994 |
Effect of ADP-ribosylation factor amino-terminal deletions on its GTP-dependent stimulation of cholera toxin activity.
Topics: Adenosine Diphosphate Ribose; ADP-Ribosylation Factor 1; ADP-Ribosylation Factors; Base Sequence; Carrier Proteins; Cholera Toxin; Cloning, Molecular; Cyclic AMP-Dependent Protein Kinases; DNA Primers; Genetic Vectors; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Kinetics; Molecular Sequence Data; Recombinant Fusion Proteins; Recombinant Proteins; Sequence Deletion | 1994 |
Choleragen catalyzes ADP-ribosylation of the stimulatory G protein heterotrimer but not its free alpha-subunit.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Aluminum; Binding Sites; Catalysis; Cholera Toxin; Fluorine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Immunoblotting; Magnesium Chloride; Precipitin Tests; Protein Binding; Tumor Cells, Cultured | 1994 |
A slowly ADP-ribosylated pertussis-toxin-sensitive GTP-binding regulatory protein is required for vasopressin-stimulated Ca2+ inflow in hepatocytes.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Epidermal Growth Factor; Fluorescent Dyes; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Heparin; Kinetics; Liver; Male; Pertussis Toxin; Rats; Rats, Wistar; Thionucleotides; Time Factors; Vasopressins; Virulence Factors, Bordetella | 1994 |
Guanine nucleotide binding regulatory proteins in liver from obese humans with and without type II diabetes: evidence for altered "cross-talk" between the insulin receptor and Gi-proteins.
Topics: Adenosine Diphosphate Ribose; Antibodies, Monoclonal; Cholera Toxin; Cytosol; Diabetes Mellitus; Diabetes Mellitus, Type 2; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Insulin; Insulin Resistance; Liver; Membrane Proteins; Obesity; Pertussis Toxin; Poly(ADP-ribose) Polymerases; Receptor Protein-Tyrosine Kinases; Receptor, Insulin; Signal Transduction; Virulence Factors, Bordetella | 1994 |
Activation of platelet phosphatidylinositide 3-kinase requires the small GTP-binding protein Rho.
Topics: Adenosine Diphosphate Ribose; Blood Platelets; Cytoskeletal Proteins; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Humans; Kinetics; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Poly(ADP-ribose) Polymerases; Recombinant Proteins; rho GTP-Binding Proteins; Thionucleotides | 1993 |
Nitric oxide signaling: a possible role for G proteins.
Topics: Adenosine Diphosphate Ribose; Base Sequence; DNA; DNA Probes; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Humans; In Vitro Techniques; Interleukin-2; Lymphocytes; Molecular Sequence Data; NF-kappa B; Nitric Oxide; Penicillamine; Promoter Regions, Genetic; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Thionucleotides | 1993 |
Role of isoprenoid metabolism in chemotactic peptide receptor-mediated G protein activation.
Topics: Adenosine Diphosphate Ribose; Anticholesteremic Agents; Cell Membrane; Cholera Toxin; Granulocytes; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Kinetics; Lovastatin; Macromolecular Substances; N-Formylmethionine Leucyl-Phenylalanine; NAD; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1993 |
Mutagenesis of the amino-terminal glycine to alanine in Gs alpha subunit alters beta gamma-dependent properties and decreases adenylylcyclase activation.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Alanine; Animals; Base Sequence; Cell Line; Cell Membrane; Centrifugation, Density Gradient; Cholera Toxin; Enzyme Activation; Glycine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Isoproterenol; Kinetics; Macromolecular Substances; Molecular Sequence Data; Mutagenesis, Site-Directed; Myristic Acid; Myristic Acids; Oligodeoxyribonucleotides; Plasmids; Polymerase Chain Reaction; Protein Biosynthesis; Protein Processing, Post-Translational; Receptors, Adrenergic, beta; RNA, Messenger; Transcription, Genetic | 1993 |
IL-8 induces the locomotion of human IL-2-activated natural killer cells. Involvement of a guanine nucleotide binding (Go) protein.
Topics: Adenosine Diphosphate Ribose; Cell Membrane; Cell Movement; Chemotaxis, Leukocyte; Cholera Toxin; Cyclic AMP; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; In Vitro Techniques; Interleukin-2; Interleukin-8; Killer Cells, Natural; Lymphocyte Activation; Pertussis Toxin; Receptors, Immunologic; Receptors, Interleukin-8A; Signal Transduction; Virulence Factors, Bordetella | 1993 |
Functional regulation of GTP-binding protein coupled to insulin-like growth factor-I receptor by lithium during G1 phase of the rat thyroid cell cycle.
Topics: Adenosine Diphosphate Ribose; Animals; Cell Line; Chlorides; G1 Phase; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Insulin-Like Growth Factor I; Lithium; Lithium Chloride; Pertussis Toxin; Rats; Receptor, IGF Type 1; Thyroid Gland; Thyrotropin; Virulence Factors, Bordetella | 1993 |
Functional domains of the Gs alpha subunit: role of the C-terminus in the receptor-dependent and receptor-independent activation.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Catalysis; Cholera Toxin; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Mutation; Peptide Fragments; Protein Biosynthesis; Receptors, Adrenergic, beta; Recombinant Proteins | 1993 |
Potentiation by cholera toxin of bradykinin-induced inositol phosphate production in the osteoblast-like cell line MC3T3-E1.
Topics: Adenosine Diphosphate Ribose; Animals; Bradykinin; Calcium; Cell Line; Cholera Toxin; Cyclic AMP; Cycloheximide; Drug Synergism; Guanosine 5'-O-(3-Thiotriphosphate); Inositol Phosphates; Isoenzymes; Mice; Osteoblasts; Pertussis Toxin; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide Phospholipase C; Phosphoric Diester Hydrolases; Protein Biosynthesis; Sodium Fluoride; Virulence Factors, Bordetella | 1993 |
Opposing influences of dexamethasone and retinoic acid on adenylate cyclase activity in ROS 17/2.8 cells.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Amino Acid Sequence; Blotting, Northern; Cell Membrane; Colforsin; Dexamethasone; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanylyl Imidodiphosphate; Isoproterenol; Molecular Sequence Data; Osteosarcoma; RNA, Messenger; Sodium Fluoride; Tretinoin; Tumor Cells, Cultured | 1993 |
Mutational analysis of G protein alpha subunit G(o) alpha expressed in Escherichia coli.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Base Sequence; Cloning, Molecular; DNA; Escherichia coli; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Kinetics; Macromolecular Substances; Molecular Sequence Data; Mutagenesis; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Pertussis Toxin; Polymerase Chain Reaction; Recombinant Proteins; Restriction Mapping; Virulence Factors, Bordetella | 1993 |
Chronic ethanol treatment increases expression of inhibitory G-proteins and reduces adenylylcyclase activity in the central nervous system of two lines of ethanol-sensitive mice.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Brain; Cell Membrane; Cerebellum; Colforsin; Corticotropin-Releasing Hormone; Ethanol; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Isoproterenol; Mice; Mice, Mutant Strains; Pertussis Toxin; Signal Transduction; Virulence Factors, Bordetella | 1993 |
Mannose 6-phosphate receptors and ADP-ribosylation factors cooperate for high affinity interaction of the AP-1 Golgi assembly proteins with membranes.
Topics: Adaptor Proteins, Vesicular Transport; Adenosine Diphosphate Ribose; ADP-Ribosylation Factors; Amino Acid Sequence; Animals; Cell Compartmentation; Cells, Cultured; Coated Vesicles; Endosomes; Golgi Apparatus; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); HeLa Cells; Humans; Intracellular Membranes; Molecular Sequence Data; Nerve Tissue Proteins; Peptides; Phosphoproteins; Protein Binding; Rats; Receptor, IGF Type 2; Sialyltransferases | 1996 |
Characterization of the G protein involved in the muscarinic stimulation of adenylyl cyclase of rat olfactory bulb.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Binding, Competitive; Carbachol; Cholera Toxin; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Immune Sera; Male; Muscarinic Agonists; N-Methylscopolamine; Neuropeptides; Olfactory Bulb; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Rats, Sprague-Dawley; Scopolamine Derivatives; Tritium | 1996 |
Uncoupling of GTP binding from target stimulation by a single mutation in the transducin alpha subunit.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adenosine Diphosphate Ribose; Alanine; Animals; Base Sequence; Cattle; Enzyme Activation; Glutamic Acid; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Molecular Sequence Data; Mutation; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Fusion Proteins; Rhodopsin; Transducin | 1996 |
G-protein regulation of outwardly rectified epithelial chloride channels incorporated into planar bilayer membranes.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Animals; Cattle; Cell Membrane; Chloride Channels; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelium; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Kinetics; Lipid Bilayers; Membrane Potentials; NAD; Pertussis Toxin; Phosphorylation; Trachea; Virulence Factors, Bordetella | 1996 |
Effect of thyroid hormones on G proteins in synaptosomes of chick embryo.
Topics: Adenosine Diphosphate Ribose; Animals; Brain; Chick Embryo; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Pertussis Toxin; Receptors, Thyroid Hormone; Synaptosomes; Thyroxine; Triiodothyronine; Virulence Factors, Bordetella | 1996 |
Neutrophil thrombospondin receptors are linked to GTP-binding proteins.
Topics: Adenosine Diphosphate Ribose; CD36 Antigens; Cell Membrane; Cells, Cultured; Chemotaxis, Leukocyte; Cholera Toxin; Cyclic GMP; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Membrane Glycoproteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Protein Binding; Signal Transduction; Thrombospondins; Virulence Factors, Bordetella | 1996 |
The AT2 receptor selectively associates with Gialpha2 and Gialpha3 in the rat fetus.
Topics: Adenosine Diphosphate Ribose; Aging; Angiotensin II; Animals; Animals, Newborn; Antibody Specificity; Cell Membrane; Fetus; Gene Expression Regulation, Developmental; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Immunoblotting; Kinetics; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Virulence Factors, Bordetella | 1996 |
Characterization of adenylyl cyclase stimulated by VIP in rat and mouse peritoneal macrophage membranes.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Cell Membrane; Cholera Toxin; Colforsin; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Intercellular Signaling Peptides and Proteins; Kinetics; Macrophages, Peritoneal; Mice; NAD; Neuropeptides; Peptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Rats, Wistar; Secretin; Sodium Fluoride; Vasoactive Intestinal Peptide | 1996 |
Identification of guanine nucleotide binding regulatory proteins in bovine tracheal smooth muscle.
Topics: Adenosine Diphosphate Ribose; Animals; Blotting, Western; Cattle; Cholera Toxin; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Intracellular Membranes; Macromolecular Substances; Microsomes; Molecular Weight; Muscle, Smooth; Pertussis Toxin; Trachea; Virulence Factors, Bordetella | 1996 |
Altered Gs alpha N-terminus affects Gs activity and interaction with the G beta gamma subunit complex in cell membranes but not in solution.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Amino Acid Sequence; Animals; Cell Membrane; Cholera Toxin; DNA, Complementary; Enzyme Activation; Genetic Vectors; GTP-Binding Protein alpha Subunits, Gs; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Macromolecular Substances; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Peptide Fragments; Poly(ADP-ribose) Polymerases; Protein Binding; Rats; Recombinant Proteins; Sequence Deletion; Solutions; Structure-Activity Relationship | 1996 |
Regulation of phosphorylation of Gi2 alpha protein controls the secretory response to isoproterenol in rat parotid tissues.
Topics: Adenosine Diphosphate Ribose; Amylases; Animals; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Enzyme Inhibitors; Ethers, Cyclic; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Isoproterenol; Male; Okadaic Acid; Parotid Gland; Phosphoprotein Phosphatases; Phosphorylation; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Secretory Rate; Signal Transduction; Up-Regulation | 1996 |
Clostridium novyi alpha-toxin-catalyzed incorporation of GlcNAc into Rho subfamily proteins.
Topics: 3T3 Cells; Acetylglucosamine; Adenosine Diphosphate Ribose; Animals; Bacterial Toxins; Glycosylation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Mice; Substrate Specificity; Uridine Diphosphate N-Acetylglucosamine | 1996 |
Role of Rho proteins in carbachol-induced contractions in intact and permeabilized guinea-pig intestinal smooth muscle.
Topics: Adenosine Diphosphate Ribose; Animals; Bacterial Proteins; Bacterial Toxins; Calcium; Carbachol; Cholinergic Agonists; Escin; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guinea Pigs; In Vitro Techniques; Intestine, Small; Male; Muscle Contraction; Muscle, Smooth; Recombinant Proteins; rhoA GTP-Binding Protein | 1996 |
Cell-permeable ceramides prevent the activation of phospholipase D by ADP-ribosylation factor and RhoA.
Topics: Adenosine Diphosphate Ribose; ADP-Ribosylation Factor 1; ADP-Ribosylation Factors; Cell Differentiation; Ceramides; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); HL-60 Cells; Humans; N-Formylmethionine Leucyl-Phenylalanine; Phospholipase D; Protein Kinase C; rhoA GTP-Binding Protein | 1997 |
The alpha2-adrenergic receptor is more effective than the galanin receptor in activating G-proteins in RINm5F beta-cell membranes.
Topics: Adenosine Diphosphate Ribose; Animals; Cell Line; Cell Membrane; Cholera Toxin; Clonidine; Galanin; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Islets of Langerhans; Kinetics; NAD; Norepinephrine; Receptors, Adrenergic, alpha-2; Receptors, Galanin; Receptors, Gastrointestinal Hormone | 1997 |
Arfaptin 1, a putative cytosolic target protein of ADP-ribosylation factor, is recruited to Golgi membranes.
Topics: Adaptor Proteins, Signal Transducing; Adenosine Diphosphate Ribose; Adenylyl Cyclases; ADP-Ribosylation Factor 1; ADP-Ribosylation Factors; Amino Acid Sequence; Animals; Base Sequence; Blotting, Western; Carrier Proteins; COS Cells; DNA, Complementary; Golgi Apparatus; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; HL-60 Cells; Humans; Molecular Sequence Data; Open Reading Frames; Receptors, Adrenergic, beta; Sequence Homology, Amino Acid | 1997 |
Gi protein activation of gonadotropin-releasing hormone-mediated protein dephosphorylation in human endometrial carcinoma.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Antineoplastic Agents, Hormonal; Buserelin; Carcinoma; Endometrial Neoplasms; Enzyme Activation; Female; Gonadotropin-Releasing Hormone; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Pertussis Toxin; Phosphorylation; Receptors, LHRH; Virulence Factors, Bordetella | 1997 |
Insulin-induced activation of NADPH-dependent H2O2 generation in human adipocyte plasma membranes is mediated by Galphai2.
Topics: Adenosine Diphosphate Ribose; Adipocytes; Cell Membrane; Cholera Toxin; Dose-Response Relationship, Drug; GTP-Binding Protein alpha Subunit, Gi2; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hydrogen Peroxide; Insulin; Manganese; NADP; NADPH Oxidases; Pertussis Toxin; Proto-Oncogene Proteins; Receptor, Insulin; Virulence Factors, Bordetella | 1997 |
Coupling of oxytocin receptor to G proteins in rat myometrium during labor: Gi receptor interaction.
Topics: Adenosine Diphosphate Ribose; Animals; Chromatography, Gel; Female; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Immunosorbent Techniques; Labor, Obstetric; Myometrium; Oxytocin; Pertussis Toxin; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, Oxytocin; Virulence Factors, Bordetella | 1997 |
Residues within the polycationic region of cGMP phosphodiesterase gamma subunit crucial for the interaction with transducin alpha subunit. Identification by endogenous ADP-ribosylation and site-directed mutagenesis.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adenosine Diphosphate Ribose; Animals; Arginine; Binding Sites; Cattle; Cyclic Nucleotide Phosphodiesterases, Type 6; GTP Phosphohydrolases; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Mutagenesis, Site-Directed; NAD; Pertussis Toxin; Rana catesbeiana; Recombinant Proteins; Transducin; Virulence Factors, Bordetella | 1997 |
Characterization of the putative alpha subunit of a heterotrimeric G protein in rice.
Topics: Adenosine Diphosphate Ribose; Antibody Specificity; Cell Compartmentation; Cell Fractionation; Cell Membrane; Cholera Toxin; DNA, Complementary; Escherichia coli; GTP-Binding Proteins; GTPase-Activating Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Oryza; Peptide Mapping; Plant Proteins; Protein Conformation; Recombinant Proteins | 1997 |
Alterations in guanine nucleotide regulatory protein expression and activity in human hepatocellular carcinoma.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Aged; Blotting, Western; Carcinoma, Hepatocellular; Colforsin; Densitometry; Female; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Liver; Liver Neoplasms; Male; Middle Aged; Pertussis Toxin; Reference Values; Virulence Factors, Bordetella | 1997 |
Opioid inhibition of adenylyl cyclase in membranes from pertussis toxin-treated NG108-15 cells.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Catalysis; Cell Membrane; Enzyme Activation; GTP Phosphohydrolases; GTP-Binding Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Hydrolysis; Kinetics; Mice; Naltrexone; Narcotics; Neuroblastoma; Pertussis Toxin; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1998 |
Regulation of phospholipase C-delta by GTP-binding proteins-rhoA as an inhibitory modulator.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; ADP Ribose Transferases; Animals; Antidotes; Botulinum Toxins; Cattle; Chemical Fractionation; Deferoxamine; Enzyme Activation; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Isoenzymes; Phospholipase C delta; rhoA GTP-Binding Protein; Sodium Fluoride; Sulfur Radioisotopes; Type C Phospholipases | 1998 |
Phospholipid- and GTP-dependent activation of cholera toxin and phospholipase D by human ADP-ribosylation factor-like protein 1 (HARL1).
Topics: Adenosine Diphosphate Ribose; ADP-Ribosylation Factors; Brain Chemistry; Catalysis; Cholera Toxin; Enzyme Activation; GTP Phosphohydrolases; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; In Vitro Techniques; Membrane Proteins; Phospholipase D; Phospholipids; Poly(ADP-ribose) Polymerases; Tissue Distribution | 1998 |
Guanine nucleotides protect Rho proteins from endogenous proteolytic degradation in renal membranes.
Topics: Adenosine Diphosphate Ribose; Animals; cdc42 GTP-Binding Protein; Cell Cycle Proteins; GTP-Binding Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Hydrolysis; Kidney; Male; Membrane Proteins; Microvilli; Peptide Hydrolases; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Recombinant Proteins; rhoA GTP-Binding Protein | 1998 |
Differential regulation of Na+ and Cl- conductances by PTX-sensitive G proteins in fetal lung apical membrane vesicles.
Topics: Adenosine Diphosphate Ribose; Animals; Anions; Cell Membrane; Cell Membrane Permeability; Chloride Channels; Dithiothreitol; Electric Conductivity; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guinea Pigs; Isethionic Acid; Liposomes; Lung; Pertussis Toxin; Sodium Channels; Sodium Radioisotopes; Thionucleotides; Virulence Factors, Bordetella | 1998 |
Role of rho proteins in agonist regulation of phospholipase D in HL-60 cells.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; ADP Ribose Transferases; Botulinum Toxins; Cell Differentiation; Clostridium botulinum; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); HL-60 Cells; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Phosphatidylinositol 4,5-Diphosphate; Phospholipase D; Phosphorylation | 1998 |
KDEL receptor (Erd2p)-mediated retrograde transport of the cholera toxin A subunit from the Golgi involves COPI, p23, and the COOH terminus of Erd2p.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Animals; Biological Transport, Active; Chlorocebus aethiops; Cholera Toxin; Coatomer Protein; Endoplasmic Reticulum; Golgi Apparatus; Guanosine 5'-O-(3-Thiotriphosphate); Immunoglobulin Fab Fragments; Immunoglobulin G; Membrane Proteins; Microtubule-Associated Proteins; Molecular Sequence Data; Mutagenesis; Rabbits; Receptors, Peptide; Tumor Suppressor Protein p53; Vero Cells | 1998 |
Guanine nucleotide binding proteins in cultured renal epithelia: studies with pertussis toxin and aldosterone.
Topics: Adenosine Diphosphate Ribose; Aldosterone; Animals; Blotting, Western; Cell Line; Cell Membrane; Cells, Cultured; Epithelial Cells; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Kidney; Membrane Proteins; Nucleic Acid Hybridization; Pertussis Toxin; Photoaffinity Labels; Reverse Transcriptase Polymerase Chain Reaction; Ribonucleases; RNA, Messenger; Virulence Factors, Bordetella; Xenopus laevis | 1999 |
Effects of T-588, a novel cognitive enhancer, on ADP-ribosylation of G(s alpha) by cholera toxin and cyclic AMP accumulation in rat cerebral cortex.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Binding Sites; Catalysis; Cerebral Cortex; Cholera Toxin; Cyclic AMP; Diethylamines; Guanosine 5'-O-(3-Thiotriphosphate); Isoproterenol; Nootropic Agents; Pertussis Toxin; Phosphorus Radioisotopes; Rats; Thiophenes; Virulence Factors, Bordetella | 1999 |
Rho and Rho kinase mediate thrombin-stimulated vascular smooth muscle cell DNA synthesis and migration.
Topics: Adenosine Diphosphate Ribose; Amides; Animals; Aorta; Cell Movement; Cells, Cultured; DNA; Enzyme Inhibitors; GTP Phosphohydrolases; GTP-Binding Proteins; GTPase-Activating Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hemostatics; Intracellular Signaling Peptides and Proteins; Male; Muscle, Smooth, Vascular; Protein Serine-Threonine Kinases; Proteins; Pyridines; Rats; Rats, Sprague-Dawley; rho GTP-Binding Proteins; rho-Associated Kinases; Sulfur Radioisotopes; Thrombin; Tritium | 1999 |
Membrane association of a new inositol 1,4,5-trisphosphate binding protein, p130 is not dependent on the pleckstrin homology domain.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Animals; Calcium Channels; Cell Membrane; COS Cells; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Peptide Fragments; Rats; Receptors, Cytoplasmic and Nuclear; Recombinant Proteins; src Homology Domains; Transfection | 1999 |
N-Myristoylation and betagamma play roles beyond anchorage in the palmitoylation of the G protein alpha(o) subunit.
Topics: Adenosine Diphosphate Ribose; Animals; Guanosine 5'-O-(3-Thiotriphosphate); Heterotrimeric GTP-Binding Proteins; Humans; Myristic Acid; Palmitic Acid; Rats | 1999 |
Evidence for stimulation of adenylyl cyclase by an activated G(s) heterotrimer in cell membranes: an experimental method for controlling the G(s) subunit composition of cell membranes.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Adjuvants, Immunologic; Cholera Toxin; Cytological Techniques; Detergents; GTP-Binding Protein alpha Subunits, Gs; GTP-Binding Protein beta Subunits; GTP-Binding Protein gamma Subunits; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Heterotrimeric GTP-Binding Proteins; Membrane Proteins; Polidocanol; Polyethylene Glycols; Signal Transduction | 2000 |
Loss of the effector function in a transducin-alpha mutant associated with Nougaret night blindness.
Topics: Adenosine Diphosphate Ribose; GTP Phosphohydrolases; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Mutagenesis, Site-Directed; Night Blindness; Transducin; Trypsin; Virulence Factors, Bordetella | 2000 |
Human RhoA/RhoGDI complex expressed in yeast: GTP exchange is sufficient for translocation of RhoA to liposomes.
Topics: 3T3 Cells; Adenosine Diphosphate Ribose; Animals; Biological Transport, Active; Guanine Nucleotide Dissociation Inhibitors; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Humans; In Vitro Techniques; Kinetics; Liposomes; Macromolecular Substances; Mice; Rabbits; Recombinant Proteins; rho Guanine Nucleotide Dissociation Inhibitor alpha; rho-Specific Guanine Nucleotide Dissociation Inhibitors; rhoA GTP-Binding Protein; Saccharomyces cerevisiae; Signal Transduction | 2000 |
Modification of adipocyte membrane adenylyl cyclase activity by NAD: evidence against NAD-induced endogenous ADP-ribosylation of Gsalpha protein.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Adipocytes; Arginine; Cell Membrane; Cell Membrane Permeability; Cholera Toxin; Cyclic AMP; Electrophoresis, Gel, Two-Dimensional; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Membrane Proteins; NAD; Poly(ADP-ribose) Polymerases; Protein Processing, Post-Translational | 2000 |
Functional analysis of farnesylation and methylation of transducin.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Animals; Base Sequence; Cattle; Chromatography, Gel; Chromatography, High Pressure Liquid; DNA Primers; Guanosine 5'-O-(3-Thiotriphosphate); Methylation; Molecular Sequence Data; Protein Binding; Protein Prenylation; Protein Processing, Post-Translational; Recombinant Proteins; Rhodopsin; Rod Cell Outer Segment; Sequence Homology, Amino Acid; Transducin; Virulence Factors, Bordetella | 2000 |
Effect of light on phosphatidate phosphohydrolase activity of retina rod outer segments: the role of transducin.
Topics: Adenosine Diphosphate Ribose; Animals; Cattle; Cell Membrane; Cholera Toxin; Darkness; Ethylmaleimide; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanylyl Imidodiphosphate; Hydrolysis; Isoenzymes; Light; Lipoprotein Lipase; Pertussis Toxin; Phosphatidate Phosphatase; Rod Cell Outer Segment; Thionucleotides; Transducin; Virulence Factors, Bordetella | 2000 |
Angiotensin II stimulates cyclic ADP-ribose formation in neonatal rat cardiac myocytes.
Topics: Adenosine Diphosphate Ribose; Age Factors; Angiotensin II; Animals; Animals, Newborn; Cell Membrane; Cells, Cultured; Cholera Toxin; Chromatography, Thin Layer; Cyclic ADP-Ribose; Dose-Response Relationship, Drug; Fluorometry; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Heart; Myocardium; Protein Binding; Rats; Rats, Wistar; Signal Transduction; Thionucleotides; Time Factors | 2000 |
Probing the mechanism of rhodopsin-catalyzed transducin activation.
Topics: Adenosine Diphosphate Ribose; Binding Sites; Binding, Competitive; Cell Membrane; Cell-Free System; Guanosine 5'-O-(3-Thiotriphosphate); Light; Models, Molecular; Mutagenesis, Site-Directed; Precipitin Tests; Protein Binding; Protein Conformation; Protein Subunits; Rhodopsin; Rod Cell Outer Segment; Transducin; Virulence Factors, Bordetella | 2001 |
Activation mechanism of Gi and Go by reactive oxygen species.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Animals; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Heterotrimeric GTP-Binding Proteins; Hydroxyl Radical; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2002 |
The small GTPase RhoA has greater expression in small cell lung carcinoma than in non-small cell lung carcinoma and contributes to their unique morphologies.
Topics: Adenocarcinoma; Adenosine Diphosphate Ribose; ADP Ribose Transferases; Botulinum Toxins; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cell Adhesion; Cell Division; Cell Size; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA, Complementary; Gene Expression Regulation, Neoplastic; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Lung Neoplasms; Neoplasm Metastasis; Neoplasm Proteins; rhoA GTP-Binding Protein; Signal Transduction | 2003 |
Third intracellular loop of glucagon like-peptide-1 receptor is coupled with endogenous mono-ADP-ribosyltransferase - novel type of receptor regulation?
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Amino Acid Sequence; Animals; Cell Membrane; CHO Cells; Cricetinae; Cricetulus; Glucagon-Like Peptide-1 Receptor; GTP-Binding Protein beta Subunits; Guanosine 5'-O-(3-Thiotriphosphate); Intracellular Space; Kinetics; Molecular Sequence Data; Peptide Fragments; Pertussis Toxin; Protein Binding; Receptors, Glucagon | 2011 |