adenosine diphosphate has been researched along with vanadates in 152 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (21.71) | 18.7374 |
| 1990's | 49 (32.24) | 18.2507 |
| 2000's | 58 (38.16) | 29.6817 |
| 2010's | 11 (7.24) | 24.3611 |
| 2020's | 1 (0.66) | 2.80 |
| Authors | Studies |
|---|---|
| Bobkov, AA; Kvorov, NV; Levitskiĭ, DI; Poglazov, BF; Shnyrov, VL | 1 |
| Cole, DG; Yount, RG | 1 |
| Muhlrad, A; Peyser, YM; Werber, MM | 1 |
| Carmeli, C; Carmeli, S; Lifshitz, Y; Ophir, R; Tadmor, O | 1 |
| Gräber, P; Wach, A | 1 |
| Bertics, PJ; Hubler, L; Kher, U | 1 |
| Muhlrad, A; Peyser, YM; Ringel, I | 1 |
| Harris, EB; Prabhakaran, K; Randhawa, B | 1 |
| Garabedian, TE; Yount, RG | 1 |
| Bukatina, AE; Khvorov, NV; Levitskiĭ, DI; Poglazov, BF; Shnyrov, VL | 1 |
| Hiratsuka, T; Mihashi, K; Ooi, A | 1 |
| Eisenberg, E; Smith, SJ | 1 |
| Hiratsuka, T | 1 |
| Moore, JM; Rao, BD; Ray, BD | 1 |
| Katayama, E | 1 |
| Inaba, K; Mohri, H | 1 |
| Nishimura, J; van Breemen, C | 1 |
| Castro, MM; Geraldes, CF | 1 |
| Aguirre, R; Cheung, HC; Gonsoulin, F; Lin, SH; Wang, CK | 1 |
| Jollès, P; Pauloin, A | 1 |
| Flatmark, T; Grønberg, M | 1 |
| Sellers, JR | 1 |
| McIntosh, DB; Ross, DC | 1 |
| Gibbons, IR; Tang, WY | 1 |
| Domigan, NM; Farnden, KJ; Monk, BC; Robertson, JG | 1 |
| Hamada, M; Morimoto, C; Okuda, H; Shimowake, A; Sumida, M | 1 |
| Cremo, CR; Grammer, JC; Yount, RG | 2 |
| Moore, JM; Reed, GH | 1 |
| Skou, JC | 1 |
| Emoto, Y; Higuchi, W; Kawamura, T; Tawada, K | 1 |
| Geeves, MA; Jeffries, TE | 1 |
| Bohnensack, R; Halangk, W | 1 |
| Bohnensack, R; Halangk, W; Kunz, W | 1 |
| Pillai, S; Zull, JE | 1 |
| Inesi, G; Nakamoto, RK | 1 |
| Nagahashi, G; Sliwinski, BJ; Tu, SI | 1 |
| Ash, DE; Leyh, TS; Reed, GH; Trentham, DR; Webb, MR | 1 |
| Glynn, IM; Richards, DE | 1 |
| Blostein, R | 1 |
| Dluzewski, AR; Gratzer, WB; Rangachari, K; Wilson, RJ | 1 |
| Bagshaw, CR; Wells, C | 1 |
| Goodno, CC; Taylor, EW | 1 |
| Maéda, Y | 1 |
| Goodno, CC | 1 |
| Ajtai, K; Biró, EN; Szilágyi, L | 1 |
| Kawamura, T; Tawada, K | 1 |
| Belagyi, J; Lörinczy, D | 1 |
| Bobkov, AA; Levitsky, DI | 1 |
| Takemori, S; Yagi, N; Yamaguchi, M | 1 |
| Sankaran, B; Senior, AE; Urbatsch, IL; Weber, J | 1 |
| Cooke, R; Cremo, CR; Luo, Y; Pate, E; Wang, D; Yount, RG | 1 |
| Hoffman, JF; Marín, R | 1 |
| Cheung, HC; Xing, J | 1 |
| Krivánek, J | 1 |
| Bobkov, AA; Golitsyna, NL; Khvorov, NV; Levitskiĭ, DI; Poglazov, BF | 1 |
| Bobkov, AA; Golitsina, NL; Khvorov, NV; Levitsky, DI | 1 |
| Romberg, L; Vale, RD | 1 |
| Carmeli, C; Carmeli, S; Hochman, Y | 1 |
| Irkens-Kiesecker, U; Müller, M; Rubinstein, B; Taiz, L | 1 |
| Rayment, I; Smith, CA | 1 |
| Baron, R; David, P; Horne, WC | 1 |
| Baiocchi, C; Camici, M; Pesi, R; Tozzi, MG | 1 |
| Rayment, I | 1 |
| Gibbons, IR; Mocz, G | 1 |
| Bobkov, AA; Dedova, IV; Golitsina, NL; Levitsky, DI; Nikolaeva, OP; Orlov, VN; Pavlov, DA | 1 |
| Holmes, KC | 1 |
| Bhagat, S; Sankaran, B; Senior, AE | 1 |
| Amzel, LM; Bianchet, M; Ko, YH; Pedersen, PL | 1 |
| Inagaki, N; Seino, S; Ueda, K | 1 |
| Cooke, R; Naber, NI; Shull, SE; Wilson, GJ | 1 |
| Pincheira, R; Wang, G; Zhang, JT; Zhang, M | 1 |
| Balnokin, Y; Dietz, KJ; Gimmler, H; Popova, L | 1 |
| Belagyi, J; Könczöl, F; Lorinczy, D | 1 |
| Callender, RH; Deng, H; Grammer, JC; Wang, J; Yount, RG | 1 |
| Ikebe, M; Maruta, S; Mitsuhashi, S; Yamada, M | 1 |
| Kakuta, Y; Negishi, M; Pedersen, LC; Petrotchenko, EV | 1 |
| Levitsky, DI; Pavlov, DA; Sobieszek, A | 1 |
| Cibert, C; Cosson, J; Fierville, F; Le Rumeur, E; Loir, M; Saudrais, C | 1 |
| Knowles, AF; Nagy, AK | 1 |
| Kamimura, S; Tani, T | 1 |
| Hong, S; Ko, YH; Pedersen, PL | 1 |
| Chu, XY; Hirohashi, T; Sugiyama, Y; Suzuki, H; Tamai, I; Tsuji, A | 1 |
| Ambudkar, SV; Sauna, ZE | 1 |
| Gros, P; Julien, M | 1 |
| Higgins, CF; Konings, WN; Margolles, A; Müller, M; van Veen, HW | 1 |
| Barrabin, H; Dutra, PM; Gadelha, FR; Lopes, AH; Meyer-Fernandes, JR; Moreira, BL; Nobrega, FB; Scofano, HM; Sodré, CL; Vercesi, AE | 1 |
| Hua, S; Inesi, G; Toyoshima, C | 1 |
| Chen, W; Crampton, DJ; Frasch, WD; Hu, CY | 1 |
| Gimi, K; Senior, AE; Urbatsch, IL; Wilke-Mounts, S | 1 |
| Davidson, AL; Sharma, S | 1 |
| Ambudkar, SV; Kerr, KM; Sauna, ZE | 1 |
| Takemori, S; Yamaguchi, M | 1 |
| Daiho, T; Danko, S; Kamidochi, M; Suzuki, H; Toyoshima, C; Yamasaki, K | 1 |
| Qu, Q; Sharom, FJ | 1 |
| Chen, J; Davidson, AL; Quiocho, FA; Sharma, S | 1 |
| Conde, M; Porras, T; Rosado, JA; Sage, SO | 1 |
| Ambudkar, SV; Muller, M; Sauna, ZE; Smith, MM | 1 |
| Cole, SP; Deeley, RG; Leslie, EM; Mao, Q; Oleschuk, CJ | 1 |
| Ajtai, K; Burghardt, TP; Muhlrad, A; Peyser, YM | 1 |
| Avraham, H; Avraham, S; Fu, Y; Kaczmarek, E; Koziak, K; Park, SY | 1 |
| Alekseev, AE; Bienengraeber, M; Dzeja, PP; Hodgson, D; Karger, AB; Terzic, A; Zingman, LV | 1 |
| Cole, SP; Deeley, RG; Gao, M; Qian, YM; Qiu, W; Westlake, CJ | 1 |
| Chang, XB; Cui, L; Hou, YX; Riordan, JR | 1 |
| Alqawi, O; Cai, J; Daoud, R; Georges, E; Gros, P; Pelletier, J | 1 |
| Toustrup-Jensen, M; Vilsen, B | 2 |
| Fisher, K; Lowe, DJ; Mitchell, CJ; Petersen, J | 1 |
| Argaraña, CE; Montich, GG; Pezza, RJ; Villarreal, MA | 1 |
| Ohkura, R; Sasaki, N; Sutoh, K | 1 |
| Gu, J; Offer, G; White, HD; Xu, S; Yu, LC | 1 |
| Qu, Q; Russell, PL; Sharom, FJ | 1 |
| Chu, JW; Qu, Q; Sharom, FJ | 1 |
| Burgess, SA; Knight, PJ; Oiwa, K; Sakakibara, H; Walker, ML | 1 |
| Senior, AE; Tombline, G; Tyndall, GA; Urbatsch, IL | 1 |
| Arai, M; Inobe, T; Kikushima, K; Kuwajima, K; Makio, T | 1 |
| Cole, SP; Deeley, RG; Gao, M; Payen, LF; Westlake, CJ | 1 |
| Basso, C; Gadsby, DC; Nairn, AC; Vergani, P | 1 |
| Bartholomew, L; Gimi, K; Senior, AE; Tombline, G; Tyndall, GA | 1 |
| Daiho, T; Danko, S; Suzuki, H; Yamasaki, K | 1 |
| Altendorf, K; Bramkamp, M; Gassel, M | 1 |
| Aureliano, M; Gutiérrez-Merino, C; Tiago, T | 1 |
| Akkerman, JW; Greinacher, A; Jedlitschky, G; Kroemer, HK; Lubenow, LE; Nieuwenhuis, HK; Tirschmann, K | 1 |
| Bartholomew, LA; Gimi, K; Senior, AE; Tombline, G; Tyndall, GA; Urbatsch, IL | 1 |
| Ambudkar, SV; Nandigama, K; Sauna, ZE | 1 |
| Cervenak, J; Köblös, G; Koomen, GJ; Német, K; Ozvegy-Laczka, C; Sarkadi, B; Schuetz, JD; Sorrentino, BP; Ujhelly, O; Váradi, A; Várady, G | 1 |
| Hsieh, T; Huang, S; Jensen, LH; Jensen, PB; Nitiss, JL; Sehested, M; Sorensen, TK; Vaughn, J; Wessel, I | 1 |
| Chen, J; Davidson, AL | 1 |
| Chang, G; Reyes, CL | 2 |
| Fachinetto, R; Nogueira, CW; Rocha, JB; Savegnago, L | 1 |
| Chait, BT; Höök, P; Mikami, A; Rosenfeld, SS; Shafer, B; Vallee, RB | 1 |
| Cole, SP; Conseil, G; Deeley, RG | 1 |
| Dey, S; Ghosh, P; Maki, N; Moitra, K | 1 |
| Chen, C; Garboczi, DN; Ko, YH; Pedersen, PL; Saxena, AK; Simcoke, WN | 1 |
| Ahmed-Belkacem, A; Di Pietro, A; Perez-Victoria, JM; Pozza, A; Sardo, A | 1 |
| Belani, JD; Cohen, JC; Hobbs, HH; Ma, Y; Sun, F; Wang, J; Xie, XS; Xu, F; Zhang, DW | 1 |
| Adamo, HP; Mazzitelli, LR | 1 |
| Levitsky, DI; Mikhailova, V; Shakirova, L; Siletskaya, E; Timofeev, VP | 1 |
| Carragher, B; Chang, G; Milligan, RA; Mulligan, S; Ward, A | 1 |
| Enkavi, G; Feng, J; Gehrig, P; Lucchinetti, E; Roschitzki, B; Schaub, MC; Tajkhorshid, E; Wang, Y; Zaugg, K; Zaugg, M | 1 |
| Chinopoulos, C; Kawamata, H; Manfredi, G; Starkov, AA | 1 |
| Gangwar, SP; Meena, SR; Saxena, AK | 1 |
| Ambudkar, SV; Bhatnagar, J; Chufan, EE; Kapoor, K; Sim, HM | 1 |
| Chinopoulos, C; Kawamata, H; Kiss, G; Starkov, AA | 1 |
| Lugo, MR; Sharom, FJ | 1 |
| Apell, HJ; Damnjanovic, B | 1 |
| Adefegha, SA; Cabral, FL; Doleski, PH; Leal, DB | 1 |
| Davies, DR; Dumais, M; Lin, T; Myler, PJ; Staker, BL; Van Voorhis, WC | 1 |
| Maurer, HH; Meyer, MR; Wagmann, L | 1 |
| Brüchert, S; Geertsma, ER; Hofmann, S; Hummer, G; Januliene, D; Kuhn, BT; Mehdipour, AR; Moeller, A; Stefan, E; Tampé, R; Thomas, C | 1 |
| Forsyth, VT; Haertlein, M; Josts, I; Kehlenbeck, DM; Moulin, M; Prevost, S; Sander, S; Tidow, H; Traore, DAK | 1 |
2 review(s) available for adenosine diphosphate and vanadates
| Article | Year |
|---|---|
The structural basis of the myosin ATPase activity.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Animals; Binding Sites; Chickens; Models, Molecular; Models, Structural; Myosin Subfragments; Myosins; Protein Structure, Secondary; Vanadates | 1996 |
The swinging lever-arm hypothesis of muscle contraction.
Topics: Actins; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Dictyostelium; Models, Biological; Models, Molecular; Models, Structural; Muscle Contraction; Muscle, Skeletal; Myosins; Protein Structure, Secondary; Vanadates | 1997 |
150 other study(ies) available for adenosine diphosphate and vanadates
| Article | Year |
|---|---|
[DTNB-light chain affects the conformation of the myosin head complexed with ADP and vanadate].
Topics: Adenosine Diphosphate; Calorimetry, Differential Scanning; Dithionitrobenzoic Acid; Myosins; Protein Conformation; Vanadates | 1992 |
Stability and photochemical properties of vanadate-trapped nucleotide complexes of gizzard myosin in the 6S and 10S conformations: identification of an active-site serine.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Amino Acid Sequence; Animals; Binding Sites; Chickens; Gizzard, Avian; Kinetics; Metals; Molecular Sequence Data; Muscle, Smooth; Myosins; Peptide Fragments; Photochemistry; Protein Binding; Protein Conformation; Sequence Homology, Nucleic Acid; Serine; Tritium; Vanadates | 1992 |
Characterization of stable beryllium fluoride, aluminum fluoride, and vanadate containing myosin subfragment 1-nucleotide complexes.
Topics: Actins; Adenosine Diphosphate; Adenosine Triphosphatases; Aluminum; Aluminum Compounds; Animals; Beryllium; Electrophoresis, Polyacrylamide Gel; Fluorides; Kinetics; Myosin Subfragments; Nucleotides; Rabbits; Temperature; Vanadates | 1992 |
Inhibition of chloroplast CF1-ATPase by vanadate.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Allosteric Regulation; Calcium; Chloroplasts; Intracellular Membranes; Kinetics; Magnetic Resonance Spectroscopy; Phosphates; Plants, Edible; Proton-Translocating ATPases; Vanadates | 1992 |
The plasma membrane H(+)-ATPase from yeast. Effects of pH, vanadate and erythrosine B on ATP hydrolysis and ATP binding.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Cell Membrane; Erythrosine; Hydrogen-Ion Concentration; Hydrolysis; Proton-Translocating ATPases; Saccharomyces cerevisiae; Vanadates | 1991 |
Potentiation of epidermal growth factor receptor protein-tyrosine kinase activity by sulfate.
Topics: Adenosine Diphosphate; Angiotensin II; Anions; Chlorides; ErbB Receptors; Fluorides; Humans; Manganese; Models, Biological; Phosphates; Phosphorylation; Polyethylene Glycols; Protein-Tyrosine Kinases; Substrate Specificity; Sulfates; Vanadates | 1992 |
Effect of actin, ATP, phosphates, and pH on vanadate-induced photocleavage of myosin subfragment 1.
Topics: Actins; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Binding Sites; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Myosin Subfragments; Myosins; Phosphates; Photolysis; Protein Conformation; Rabbits; Ultraviolet Rays; Vanadates | 1991 |
Active transport of ATP and presence of a vanadate-sensitive membrane-bound ATPase in Mycobacterium leprae.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Biological Transport, Active; Cyanides; Ethylmaleimide; Hydrogen-Ion Concentration; Kinetics; Mycobacterium leprae; Vanadates | 1991 |
Direct photoaffinity labeling of gizzard myosin with vanadate-trapped adenosine diphosphate.
Topics: Adenosine Diphosphate; Affinity Labels; Amino Acid Sequence; Animals; Chickens; Chromatography, High Pressure Liquid; Gizzard, Avian; Molecular Sequence Data; Myosins; Peptide Biosynthesis; Tritium; Vanadates | 1991 |
[Calorimetric proofs for 2 conformational states of the myosin subfragment-1 complex with nucleotides].
Topics: Adenosine Diphosphate; Animals; Binding Sites; Calorimetry, Differential Scanning; Myosin Subfragments; Nucleotides; Protein Conformation; Rabbits; Ultraviolet Rays; Vanadates | 1990 |
Evidence for the existence of two equilibrium conformations of the ternary complex of myosin subfragment-1, ADP, and orthovanadate.
Topics: Adenosine Diphosphate; Animals; Ca(2+) Mg(2+)-ATPase; Glycerol; Isoenzymes; Kinetics; Muscles; Myosin Subfragments; Nucleotides; Protein Conformation; Rabbits; Spectrometry, Fluorescence; Temperature; Vanadates | 1990 |
A comparison of the effect of vanadate on the binding of myosin-subfragment-1.ADP to actin and on actomyosin subfragment 1 ATPase activity.
Topics: Actins; Actomyosin; Adenosine Diphosphate; Adenosine Triphosphate; Animals; In Vitro Techniques; Kinetics; Light; Macromolecular Substances; Muscles; Myosin Subfragments; Myosins; Rabbits; Scattering, Radiation; Vanadates | 1990 |
Transmission of ADP.vanadate-induced conformational changes to three peptide segments of myosin subfragment-1.
Topics: 4-Chloro-7-nitrobenzofurazan; Adenosine Diphosphate; Animals; Anthracenes; Fluoresceins; Fluorescent Dyes; Kinetics; Muscles; Myosin Subfragments; Peptide Fragments; Protein Binding; Protein Conformation; Rabbits; Spectrometry, Fluorescence; Vanadates | 1990 |
31P NMR studies of enzyme-bound substrate complexes of yeast 3-phosphoglycerate kinase: III. Two ADP binding sites and their Mg(II) affinity; effects of vanadate and arsenate on enzymic complexes with ADP and 3-P-glycerate.
Topics: Adenosine Diphosphate; Arsenates; Binding Sites; Glyceric Acids; Magnesium; Magnetic Resonance Spectroscopy; Phosphoglycerate Kinase; Vanadates; Yeasts | 1990 |
The effects of various nucleotides on the structure of actin-attached myosin subfragment-1 studied by quick-freeze deep-etch electron microscopy.
Topics: Actins; Adenosine Diphosphate; Adenosine Triphosphate; Aluminum Silicates; Cross-Linking Reagents; Freeze Etching; Hydrolysis; Microscopy, Electron; Myosin Subfragments; Protein Binding; Staining and Labeling; Surface Properties; Vanadates | 1989 |
Dynamic conformational changes of 21 S dynein ATPase coupled with ATP hydrolysis revealed by proteolytic digestion.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Cations, Divalent; Chymotrypsin; Dyneins; Electrophoresis, Polyacrylamide Gel; Hydrolysis; Kinetics; Male; Molecular Weight; Peptide Fragments; Protein Conformation; Sea Urchins; Serine Endopeptidases; Spermatozoa; Thermolysin; Trypsin; Vanadates | 1989 |
Possible involvement of actomyosin ADP complex in regulation of Ca2+ sensitivity in alpha-toxin permeabilized smooth muscle.
Topics: Actomyosin; Adenosine Diphosphate; Animals; Calcium; Cell Membrane Permeability; Cobra Neurotoxin Proteins; Elapid Venoms; In Vitro Techniques; Kinetics; Mesenteric Arteries; Models, Theoretical; Muscle Contraction; Muscle, Smooth, Vascular; Protein Binding; Rabbits; Thionucleotides; Vanadates | 1989 |
Multinuclear NMR study of the interaction of vanadate with mononucleotides, ADP, and ATP.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Esterification; Ligands; Magnetic Resonance Spectroscopy; Models, Chemical; Nucleotides; Vanadates | 1989 |
Characterization of the ethenoadenosine diphosphate binding site of myosin subfragment 1. Energetics of the equilibrium between two states of nucleotide.S1 and vanadate-induced global conformation changes detected by energy transfer.
Topics: Adenosine Diphosphate; Animals; Binding Sites; Energy Transfer; Fluorescent Dyes; Kinetics; Mathematics; Muscles; Myosin Subfragments; Myosins; Peptide Fragments; Protein Conformation; Rabbits; Spectrometry, Fluorescence; Thermodynamics; Vanadates | 1989 |
Presence of a MgATP/ADP-dependent pp50 phosphatase in bovine brain coated vesicles.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Brain; Cattle; Chlorpromazine; Coated Pits, Cell-Membrane; Dibucaine; Endosomes; Phosphates; Phosphoproteins; Phosphoric Monoester Hydrolases; Sodium Fluoride; Time Factors; Trifluoperazine; Vanadates; Vanadium | 1986 |
Studies on Mg2+-dependent ATPase in bovine adrenal chromaffin granules. With special reference to the effect of inhibitors and energy coupling.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adrenal Medulla; Animals; Ca(2+) Mg(2+)-ATPase; Cattle; Chromaffin Granules; Chromaffin System; Dicyclohexylcarbodiimide; Ethylmaleimide; Hydrogen-Ion Concentration; Hydrolysis; Phenanthrolines; Proton-Translocating ATPases; Temperature; Vanadates; Vanadium | 1987 |
Mechanism of the phosphorylation-dependent regulation of smooth muscle heavy meromyosin.
Topics: Adenosine Diphosphate; Animals; Ca(2+) Mg(2+)-ATPase; Gizzard, Avian; Kinetics; Mathematics; Muscle, Smooth; Myosin Subfragments; Nephelometry and Turbidimetry; Phosphates; Phosphorylation; Time Factors; Turkeys; Vanadates; Vanadium | 1985 |
Intramolecular cross-linking at the active site of the Ca2+-ATPase of sarcoplasmic reticulum. High and low affinity nucleotide binding and evidence of active site closure in E2-P.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aldehydes; Animals; Binding Sites; Calcium-Transporting ATPases; Cross-Linking Reagents; Glutaral; Kinetics; Muscles; Phosphates; Rabbits; Sarcoplasmic Reticulum; Vanadates | 1987 |
Photosensitized cleavage of dynein heavy chains. Cleavage at the V2 site by irradiation at 365 NM in the presence of oligovanadate.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Affinity Labels; Animals; Azides; Binding Sites; Cytidine Triphosphate; Dyneins; Electrophoresis, Polyacrylamide Gel; Molecular Weight; Photolysis; Sea Urchins; Time Factors; Uridine Triphosphate; Vanadates | 1987 |
Characterization of the peribacteroid membrane ATPase of lupin root nodules.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Cations; Cell Membrane; Fabaceae; Hydrogen-Ion Concentration; Kinetics; Magnesium; Magnesium Chloride; Manganese; Plants; Plants, Medicinal; Rhizobium; Sodium Fluoride; Substrate Specificity; Vanadates | 1988 |
Ca2+ uptake in bovine adrenocortical microsomes: formation of phosphorylated intermediate of Ca2+ dependent ATPase.
Topics: Adenosine Diphosphate; Adrenal Cortex; Animals; Biological Transport, Active; Calcimycin; Calcium; Calcium-Transporting ATPases; Cattle; Magnesium; Microsomes; Phosphoproteins; Temperature; Vanadates | 1988 |
UV-induced vanadate-dependent modification and cleavage of skeletal myosin subfragment 1 heavy chain. 1. Evidence for active site modification.
Topics: Adenosine Diphosphate; Animals; Binding Sites; Calcium-Transporting ATPases; In Vitro Techniques; Muscles; Myosin Subfragments; Myosins; Peptide Fragments; Rabbits; Ultraviolet Rays; Vanadates | 1988 |
Coordination scheme and stereochemical configuration of manganese(II) adenosine 5'-diphosphate at the active site of 3-phosphoglycerate kinase.
Topics: Adenosine Diphosphate; Electron Spin Resonance Spectroscopy; Glyceric Acids; Magnetic Resonance Spectroscopy; Molecular Conformation; Phosphoglycerate Kinase; Protein Binding; Protein Conformation; Saccharomyces cerevisiae; Vanadates; Vanadium | 1985 |
The sodium, potassium-pump.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Biological Transport, Active; Cardiac Glycosides; Energy Metabolism; Kinetics; Phosphorylation; Potassium; Sodium; Sodium-Potassium-Exchanging ATPase; Vanadates; Vanadium | 1986 |
UV-induced vanadate-dependent modification and cleavage of skeletal myosin subfragment 1 heavy chain. 2. Oxidation of serine in the 23-kDa NH2-terminal tryptic peptide.
Topics: Adenosine Diphosphate; Animals; Binding Sites; Hydrogen-Ion Concentration; In Vitro Techniques; Muscles; Myosin Subfragments; Myosins; Oxidation-Reduction; Peptide Fragments; Rabbits; Serine; Trypsin; Ultraviolet Rays; Vanadates | 1988 |
Relationship between the ATPase activity and the ATP-induced fluorescence enhancement of SH-modified heavy meromyosin during its fractional inactivation by vanadate plus ADP: evidence for heterogeneity in the active sites.
Topics: Actins; Adenosine Diphosphate; Adenosine Triphosphatases; Binding Sites; Ca(2+) Mg(2+)-ATPase; Enzyme Activation; Hydrolysis; Kinetics; Myosin Subfragments; Spectrometry, Fluorescence; Thimerosal; Vanadates; Vanadium | 1985 |
The effect of nucleotide upon a specific isomerization of actomyosin subfragment 1.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Ethylene Glycol; Ethylene Glycols; Isomerism; Light; Myosin Subfragments; Myosins; Nucleotides; Peptide Fragments; Phosphates; Potassium Chloride; Scattering, Radiation; Spectrometry, Fluorescence; Vanadates | 1988 |
Control of respiration and of motility in ejaculated bull spermatozoa.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cattle; Cyanides; Male; Mitochondria; Nephelometry and Turbidimetry; Oxidative Phosphorylation; Oxygen Consumption; Sperm Motility; Spermatozoa; Vanadates; Vanadium | 1986 |
Interdependence of mitochondrial ATP production and extramitochondrial ATP utilization in intact spermatozoa.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Caffeine; Cattle; Energy Metabolism; In Vitro Techniques; Lactates; Lactic Acid; Male; Mitochondria; Oxidative Phosphorylation; Oxygen Consumption; Sperm Motility; Spermatozoa; Vanadates; Vanadium | 1985 |
ATP activation of protein degradation by extracts of crude and purified lysosomal preparations.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cathepsin D; Cytidine Triphosphate; Guanosine Triphosphate; Hydrogen-Ion Concentration; Hydrolysis; In Vitro Techniques; Kidney Cortex; Liver; Lysosomes; Molybdenum; Protease Inhibitors; Proteins; Rats; Serum Albumin, Bovine; Vanadates; Vanadium | 1985 |
Studies of the interactions of 2',3'-O-(2,4,6-trinitrocyclohexyldienylidine)adenosine nucleotides with the sarcoplasmic reticulum (Ca2+ + Mg2+)-ATPase active site.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Animals; Binding Sites; Ca(2+) Mg(2+)-ATPase; Calcium-Transporting ATPases; Fluorescent Dyes; Kinetics; Muscles; Protein Binding; Rabbits; Sarcoplasmic Reticulum; Spectrometry, Fluorescence; Vanadates; Vanadium | 1984 |
Regulatory effects of adenosine diphosphate on the activity of the plasma membrane ATPase of corn roots.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Cell Membrane; Dicyclohexylcarbodiimide; Diethylstilbestrol; Kinetics; Miconazole; Microsomes; Plants; Vanadates; Vanadium; Zea mays | 1984 |
Electron paramagnetic resonance studies of MN(II) complexes with myosin subfragment 1 and oxygen 17-labeled ligands.
Topics: Adenosine Diphosphate; Animals; Electron Spin Resonance Spectroscopy; Ligands; Manganese; Muscles; Myosin Subfragments; Myosins; Oxygen Isotopes; Peptide Fragments; Protein Binding; Rabbits; Vanadates; Vanadium | 1982 |
Occlusion of rubidium ions by the sodium-potassium pump: its implications for the mechanism of potassium transport.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Biological Transport, Active; Ion Channels; Kidney; Potassium; Radioisotopes; Rubidium; Sodium; Sodium-Potassium-Exchanging ATPase; Swine; Vanadates; Vanadium | 1982 |
Sodium pump-catalyzed sodium-sodium exchange associated with ATP hydrolysis.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Biological Transport, Active; Erythrocyte Membrane; Erythrocytes; Humans; Kinetics; Potassium; Sodium; Sodium-Potassium-Exchanging ATPase; Vanadates; Vanadium | 1983 |
A cytoplasmic requirement of red cells for invasion by malarial parasites.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cyclic AMP; Cytoplasm; Erythrocyte Membrane; Erythrocytes; Fetal Blood; Hematocrit; Humans; In Vitro Techniques; Malaria; Plasmodium falciparum; Vanadates; Vanadium | 1983 |
The characterization of vanadate-trapped nucleotide complexes with spin-labelled myosins.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Animals; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; In Vitro Techniques; Magnesium; Mollusca; Myosins; Rabbits; Spin Labels; Vanadates; Vanadium | 1984 |
Inhibition of actomyosin ATPase by vanadate.
Topics: Actins; Adenosine Diphosphate; Adenosine Triphosphatases; Animals; Kinetics; Muscles; Rabbits; Vanadates; Vanadium | 1982 |
On the intensity reversal of the "tropomyosin reflexions" in X-ray diffraction patterns from crab striated muscle.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Brachyura; Calcium; In Vitro Techniques; Magnesium; Muscle Contraction; Muscle Relaxation; Muscles; Thionucleotides; Tropomyosin; Vanadates; Vanadium; X-Ray Diffraction | 1984 |
Myosin active-site trapping with vanadate ion.
Topics: Actins; Adenosine Diphosphate; Animals; Binding Sites; Kinetics; Methods; Myosins; Protein Binding; Vanadates; Vanadium | 1982 |
Study of the structure of HMM . Vanadate complex.
Topics: Actins; Adenosine Diphosphate; Adenosine Triphosphate; Myosin Subfragments; Phosphates; Protein Conformation; Trypsin; Ultracentrifugation; Vanadates; Vanadium | 1982 |
Dissociation of actomyosin by vanadate plus ADP, and decomposition of the myosin-ADP-vanadate complex by actin.
Topics: Actins; Actomyosin; Adenosine Diphosphate; Animals; Chemical Phenomena; Chemistry; Myosin Subfragments; Protein Binding; Rabbits; Time Factors; Vanadates; Vanadium; Viscosity | 1982 |
Effects of nucleotide on skeletal muscle myosin unfolding in myofibrils by DSC.
Topics: Actomyosin; Adenosine Diphosphate; Animals; Calorimetry, Differential Scanning; Muscle Contraction; Myosins; Protein Denaturation; Rabbits; Thermodynamics; Vanadates | 1995 |
Differential scanning calorimetric study of the complexes of myosin subfragment 1 with nucleoside diphosphates and vanadate or beryllium fluoride.
Topics: Adenosine Diphosphate; Beryllium; Calorimetry, Differential Scanning; Cytidine Diphosphate; Fluorides; Guanosine Diphosphate; Inosine Diphosphate; Myosin Subfragments; Nucleotides; Protein Conformation; Thermodynamics; Uridine Diphosphate; Vanadates | 1995 |
An X-ray diffraction study on a single frog skinned muscle fiber in the presence of vanadate.
Topics: Adenosine Diphosphate; Animals; Muscle Fibers, Skeletal; Muscle, Skeletal; Myosins; Rana catesbeiana; Vanadates; X-Ray Diffraction | 1995 |
P-glycoprotein is stably inhibited by vanadate-induced trapping of nucleotide at a single catalytic site.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Catalysis; Cell Membrane; CHO Cells; Cricetinae; Enzyme Activation; Kinetics; Temperature; Ultraviolet Rays; Vanadates | 1995 |
Photoaffinity ADP analogs as covalently attached reporter groups of the active site of myosin subfragment 1.
Topics: Acrylamides; Actins; Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Animals; Azides; Binding Sites; Binding, Competitive; Chickens; Edetic Acid; Fluorescent Dyes; Myosin Subfragments; Myosins; Osmolar Concentration; Photochemistry; Rabbits; Spectrometry, Fluorescence; Vanadates | 1995 |
ADP+orthophosphate (P(i)) stimulates an Na/K pump-mediated coefflux of P(i) and Na in human red blood cell ghosts.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Erythrocyte Membrane; Humans; Ion Transport; Oligomycins; Ouabain; Phosphates; Potassium; Sodium; Sodium-Potassium-Exchanging ATPase; Vanadates | 1994 |
Vanadate-induced changes in myosin subfragment-1 from cardiac muscle.
Topics: Adenosine Diphosphate; Animals; Cattle; Fluorescence Polarization; Fluorescent Dyes; Kinetics; Myocardium; Myosin Subfragments; Protein Conformation; Spectrometry, Fluorescence; Vanadates | 1994 |
Effect of vanadium ions on ATP citrate lyase.
Topics: Adenosine Diphosphate; Animals; ATP Citrate (pro-S)-Lyase; Binding Sites; Citrates; Citric Acid; Coenzyme A; Histidine; Kinetics; Liver; Male; Phosphorylation; Rats; Vanadates | 1994 |
[Formation of stabile complexes of myosin subfragment-1 with ADP and orthovanadate or beryllium fluoride in the presence of calcium ions].
Topics: Adenosine Diphosphate; Animals; Beryllium; Calcium; Fluorides; Myosin Subfragments; Rabbits; Thermodynamics; Vanadates | 1993 |
Calorimetric characterization of the stable complex of myosin subfragment 1 with ADP and beryllium fluoride.
Topics: Adenosine Diphosphate; Animals; Beryllium; Calorimetry, Differential Scanning; Fluorides; Myosin Subfragments; Protein Folding; Rabbits; Vanadates | 1993 |
Chemomechanical cycle of kinesin differs from that of myosin.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Aluminum; Aluminum Compounds; Animals; Cytoskeleton; Decapodiformes; Fluorides; Kinesins; Kinetics; Microtubules; Myosins; Vanadates | 1993 |
Vanadate, a transition state inhibitor of chloroplast CF1-ATPase.
Topics: Adenosine Diphosphate; Calcium; Chloroplasts; Kinetics; Plants; Proton-Translocating ATPases; Vanadates | 1993 |
On the mechanism of hyperacidification in lemon. Comparison of the vacuolar H(+)-ATPase activities of fruits and epicotyls.
Topics: Adenosine Diphosphate; Biological Transport, Active; Chlorides; Citrus; Enzyme Inhibitors; Hydrogen-Ion Concentration; Intracellular Membranes; Kinetics; Nitrates; Oxidation-Reduction; Proton-Translocating ATPases; Solubility; Vacuoles; Vanadates | 1996 |
X-ray structure of the magnesium(II).ADP.vanadate complex of the Dictyostelium discoideum myosin motor domain to 1.9 A resolution.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Animals; Binding Sites; Crystallography, X-Ray; Dictyostelium; Hydrogen Bonding; Magnesium; Models, Molecular; Molecular Sequence Data; Myosin Subfragments; Protein Conformation; Protein Structure, Tertiary; Vanadates | 1996 |
Vanadate inhibits vacuolar H(+)-ATPase-mediated proton transport in chicken kidney microsomes by an ADP-dependent mechanism.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Chickens; Enzyme Inhibitors; Hydrogen-Ion Concentration; Kidney; Kinetics; Microsomes; Proton-Translocating ATPases; Vacuoles; Vanadates | 1996 |
Synergistic action of ADP and 2,3-bisphosphoglycerate on the modulation of cytosolic 5'-nucleotidase.
Topics: 2,3-Diphosphoglycerate; 5'-Nucleotidase; Adenosine Diphosphate; Animals; Cattle; Chromatography, Affinity; Chromatography, Gel; Cytosol; Diphosphoglyceric Acids; Drug Synergism; Kinetics; Thymus Gland; Vanadates | 1996 |
Phase partition analysis of nucleotide binding to axonemal dynein.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Binding Sites; Calcium; Dextrans; Dyneins; Edetic Acid; Iron; Male; Polyethylene Glycols; Protein Binding; Sea Urchins; Sperm Tail; Vanadates | 1996 |
Differential scanning calorimetric study of the complexes of modified myosin subfragment 1 with ADP and vanadate or beryllium fluoride.
Topics: Adenosine Diphosphate; Animals; Beryllium; Calorimetry, Differential Scanning; Fluorides; Indicators and Reagents; Lysine; Methylation; Myosin Subfragments; Picrates; Rabbits; Structure-Activity Relationship; Sulfhydryl Compounds; Vanadates | 1996 |
Inhibition of P-glycoprotein ATPase activity by procedures involving trapping of nucleotide in catalytic sites.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Affinity Labels; Aluminum; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Beryllium; Binding Sites; Cell Membrane; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Fluorides; Fluorine; Kinetics; Membrane Proteins; Ultraviolet Rays; Vanadates | 1997 |
Novel insights into the chemical mechanism of ATP synthase. Evidence that in the transition state the gamma-phosphate of ATP is near the conserved alanine within the P-loop of the beta-subunit.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alanine; Amino Acid Sequence; Animals; Borohydrides; Conserved Sequence; Hydrolysis; Kinetics; Magnesium Chloride; Male; Models, Chemical; Molecular Sequence Data; Organophosphates; Oxidation-Reduction; Protein Conformation; Protein Structure, Secondary; Proton-Translocating ATPases; Rats; Rats, Sprague-Dawley; Ultraviolet Rays; Vanadates | 1997 |
MgADP antagonism to Mg2+-independent ATP binding of the sulfonylurea receptor SUR1.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Azides; Binding Sites; Cricetinae; Magnesium; Point Mutation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, Drug; Recombinant Proteins; Structure-Activity Relationship; Sulfonylurea Receptors; Vanadates | 1997 |
Myosin head interactions in Ca2+-activated skinned rabbit skeletal muscle fibers.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Electron Spin Resonance Spectroscopy; In Vitro Techniques; Isometric Contraction; Muscle Fibers, Slow-Twitch; Muscle, Skeletal; Myosins; Rabbits; Spin Labels; Spin Trapping; Vanadates | 1997 |
Conformational changes of P-glycoprotein by nucleotide binding.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blotting, Western; Cell Line; Ethylmaleimide; Humans; Magnesium; Models, Biological; Molecular Structure; Nucleotides; Ouabain; Protein Binding; Protein Conformation; Trypsin; Vanadates | 1997 |
Na+-ATPase from the plasma membrane of the marine alga Tetraselmis (Platymonas) viridis forms a phosphorylated intermediate.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Cation Transport Proteins; Cell Membrane; Enzyme Inhibitors; Eukaryota; Molecular Weight; Phosphoproteins; Phosphorylation; Sodium; Vanadates | 1998 |
Effect of oxygen free radicals on myosin in muscle fibres.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cesium; Cysteine; Electron Spin Resonance Spectroscopy; Hydrolysis; Hydroxyl Radical; In Vitro Techniques; Muscle Fibers, Skeletal; Myosins; Oxidants; Oxidation-Reduction; Psoas Muscles; Rabbits; Spin Labels; Sulfhydryl Compounds; Ultraviolet Rays; Vanadates | 1998 |
Raman difference spectroscopic studies of the myosin S1.MgADP.vanadate complex.
Topics: Adenosine Diphosphate; Animals; Anions; Binding Sites; Catalysis; Hydrolysis; Macromolecular Substances; Models, Chemical; Myosin Subfragments; Rabbits; Solutions; Spectrum Analysis, Raman; Vanadates | 1998 |
ADP/vanadate mediated photocleavage of myosin light chain kinase at the autoinhibitory region.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Amino Acids; Animals; Calmodulin; Cattle; Chickens; Hydrolysis; Kinetics; Molecular Sequence Data; Myosin-Light-Chain Kinase; Phosphorylation; Photochemistry; Turkey; Ultraviolet Rays; Vanadates | 1998 |
The sulfuryl transfer mechanism. Crystal structure of a vanadate complex of estrogen sulfotransferase and mutational analysis.
Topics: Adenosine Diphosphate; Animals; Catalytic Domain; Crystallography; DNA Mutational Analysis; Mice; Models, Molecular; Mutagenesis, Site-Directed; Sulfotransferases; Synchrotrons; Vanadates | 1998 |
Calorimetric studies of the thermal unfolding of smooth muscle myosin fragments and their complexes with ADP and phosphate analogs.
Topics: Adenosine Diphosphate; Aluminum Compounds; Animals; Beryllium; Calorimetry, Differential Scanning; Fluorides; Gizzard, Avian; Hot Temperature; Kinetics; Muscle, Smooth; Myosin Subfragments; Myosins; Phosphates; Protein Denaturation; Protein Folding; Thermodynamics; Turkeys; Vanadates | 1998 |
The use of phosphocreatine plus ADP as energy source for motility of membrane-deprived trout spermatozoa.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylate Kinase; Animals; Cell Membrane; Creatine Kinase; Cyclic AMP; Dinitrofluorobenzene; Dinucleoside Phosphates; Magnetic Resonance Spectroscopy; Male; Microscopy, Video; Models, Biological; Oncorhynchus mykiss; Phosphocreatine; Sperm Motility; Sperm Tail; Spermatozoa; Trypsin; Vanadates | 1998 |
Inhibition of an ecto-ATP-diphosphohydrolase by azide.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Azides; Chickens; Diphosphates; Enzyme Inhibitors; Fluorides; Hydrogen-Ion Concentration; Hydrolysis; Oviducts; Vanadates | 1999 |
Dynein-ADP as a force-generating intermediate revealed by a rapid reactivation of flagellar axoneme.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Dyneins; Flagella; Kinetics; Male; Microscopy; Oscillometry; Photolysis; Sea Urchins; Sperm Tail; Stress, Mechanical; Vanadates | 1999 |
Chemical mechanism of ATP synthase. Magnesium plays a pivotal role in formation of the transition state where ATP is synthesized from ADP and inorganic phosphate.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Animals; ATP Synthetase Complexes; Binding Sites; Magnesium; Mitochondria, Liver; Models, Molecular; Molecular Sequence Data; Multienzyme Complexes; Oxygen; Peptide Fragments; Phosphates; Phosphotransferases (Phosphate Group Acceptor); Proton-Translocating ATPases; Rats; Rats, Sprague-Dawley; Sequence Analysis; Ultraviolet Rays; Vanadates | 1999 |
Function and expression of multidrug resistance-associated protein family in human colon adenocarcinoma cells (Caco-2).
Topics: Adenosine Diphosphate; Adenosine Triphosphate; ATP-Binding Cassette Transporters; Biological Transport, Active; Blotting, Northern; Caco-2 Cells; Cytidine Triphosphate; Dose-Response Relationship, Drug; Drug Interactions; Estradiol; Glucuronides; Glutathione; Guanosine Triphosphate; Humans; Ligands; Microvilli; Multidrug Resistance-Associated Proteins; Nucleotides; Osmolar Concentration; Reverse Transcriptase Polymerase Chain Reaction; Time Factors; Uridine Triphosphate; Vanadates | 2000 |
Evidence for a requirement for ATP hydrolysis at two distinct steps during a single turnover of the catalytic cycle of human P-glycoprotein.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Cell Membrane; DNA, Complementary; Genes, MDR; Humans; Hydrolysis; Kinetics; Models, Biological; Photoaffinity Labels; Protein Binding; Protein Conformation; Time Factors; Vanadates | 2000 |
Nucleotide-induced conformational changes in P-glycoprotein and in nucleotide binding site mutants monitored by trypsin sensitivity.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Amino Acid Sequence; Amino Acid Substitution; Animals; Antibodies, Monoclonal; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Epitopes; Hydrolysis; Magnesium Chloride; Mice; Molecular Weight; Mutation; Nucleotides; Peptide Fragments; Protein Conformation; Trypsin; Vanadates | 2000 |
The homodimeric ATP-binding cassette transporter LmrA mediates multidrug transport by an alternating two-site (two-cylinder engine) mechanism.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Allosteric Regulation; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Bacterial Proteins; Benzimidazoles; Binding Sites; Biological Transport, Active; Calcium Channel Blockers; Catalysis; Cell Membrane; Dimerization; Drug Resistance, Multiple; Isoquinolines; Lactococcus lactis; Liposomes; Models, Molecular; Multidrug Resistance-Associated Proteins; Mutagenesis, Site-Directed; Photoaffinity Labels; Protein Structure, Tertiary; Quinazolines; Recombinant Fusion Proteins; Vanadates; Vinblastine | 2000 |
Characterization of the intracellular Ca(2+) pools involved in the calcium homeostasis in Herpetomonas sp. promastigotes.
Topics: Adenosine Diphosphate; Animals; Anti-Bacterial Agents; Antimycin A; Biological Transport; Calcimycin; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Digitonin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanosine Triphosphate; Indicators and Reagents; Inositol 1,4,5-Trisphosphate; Intracellular Membranes; Ionophores; Macrolides; Membrane Potentials; Mitochondria; Oligomycins; Ruthenium Red; Sodium-Calcium Exchanger; Thapsigargin; Time Factors; Trypanosomatina; Uncoupling Agents; Vanadates | 2000 |
Distinct topologies of mono- and decavanadate binding and photo-oxidative cleavage in the sarcoplasmic reticulum ATPase.
Topics: Adenosine Diphosphate; Animals; Binding Sites; Calcium; Calcium-Transporting ATPases; Hydrogen-Ion Concentration; Models, Chemical; Oxidation-Reduction; Rabbits; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Ultraviolet Rays; Vanadates | 2000 |
Characterization of the metal binding environment of catalytic site 1 of chloroplast F1-ATPase from Chlamydomonas.
Topics: Adenosine Diphosphate; Animals; Aspartic Acid; Binding Sites; Catalysis; Chlamydomonas reinhardtii; Chloroplasts; Electron Spin Resonance Spectroscopy; Glutamic Acid; Mutagenesis, Site-Directed; Protein Conformation; Proton-Translocating ATPases; Spin Labels; Vanadates | 2000 |
Investigation of the role of glutamine-471 and glutamine-1114 in the two catalytic sites of P-glycoprotein.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aluminum; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Azides; Beryllium; Binding, Competitive; Ca(2+) Mg(2+)-ATPase; Catalytic Domain; Enzyme Activation; Enzyme Inhibitors; Fluorides; Fluorine; Glutamine; Magnesium; Mice; Mutagenesis, Site-Directed; Photoaffinity Labels; Recombinant Proteins; Vanadates | 2000 |
Vanadate-induced trapping of nucleotides by purified maltose transport complex requires ATP hydrolysis.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Adenylyl Imidodiphosphate; ATP-Binding Cassette Transporters; Bacterial Proteins; Carrier Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Escherichia coli Proteins; Hydrolysis; Maltose; Maltose-Binding Proteins; Membrane Proteins; Monosaccharide Transport Proteins; Mutagenesis, Site-Directed; Periplasmic Binding Proteins; Recombinant Fusion Proteins; Vanadates | 2000 |
Correlation between steady-state ATP hydrolysis and vanadate-induced ADP trapping in Human P-glycoprotein. Evidence for ADP release as the rate-limiting step in the catalytic cycle and its modulation by substrates.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Catalysis; Humans; Hydrolysis; Kinetics; Vanadates | 2001 |
Activating efficiency of Ca2+ and cross-bridges as measured by phosphate analog release.
Topics: Actins; Adenosine Diphosphate; Adenosine Triphosphate; Aluminum Compounds; Animals; Biophysical Phenomena; Biophysics; Calcium; Fluorides; In Vitro Techniques; Muscle Contraction; Muscle, Skeletal; Myosins; Rabbits; Vanadates | 2001 |
ADP-insensitive phosphoenzyme intermediate of sarcoplasmic reticulum Ca(2+)-ATPase has a compact conformation resistant to proteinase K, V8 protease and trypsin.
Topics: Adenosine Diphosphate; Animals; Binding Sites; Calcium; Calcium-Transporting ATPases; Endopeptidase K; Fluorides; Hydrogen-Ion Concentration; Magnesium; Phosphoproteins; Phosphorylation; Protein Binding; Protein Conformation; Rabbits; Sarcoplasmic Reticulum; Serine Endopeptidases; Trypsin; Vanadates | 2001 |
FRET analysis indicates that the two ATPase active sites of the P-glycoprotein multidrug transporter are closely associated.
Topics: 4-Chloro-7-nitrobenzofurazan; Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphatases; Anilino Naphthalenesulfonates; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Catalysis; CHO Cells; Cricetinae; Energy Transfer; Fluorescent Dyes; Macromolecular Substances; Magnesium; Membrane Proteins; Protein Structure, Tertiary; Spectrometry, Fluorescence; Vanadates | 2001 |
Trapping the transition state of an ATP-binding cassette transporter: evidence for a concerted mechanism of maltose transport.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; ATP-Binding Cassette Transporters; Bacterial Proteins; Biological Transport; Carrier Proteins; Escherichia coli Proteins; Maltose; Maltose-Binding Proteins; Membrane Proteins; Monosaccharide Transport Proteins; Periplasmic Binding Proteins; Vanadates | 2001 |
Cyclic nucleotides modulate store-mediated calcium entry through the activation of protein-tyrosine phosphatases and altered actin polymerization in human platelets.
Topics: Actins; Adenosine Diphosphate; Alprostadil; Arsenicals; Blood Platelets; Calcium; Carbazoles; Cyclic AMP; Cyclic GMP; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Humans; In Vitro Techniques; Indoles; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nitroprusside; Phosphorylation; Platelet Activation; Platelet Aggregation Inhibitors; Protein Tyrosine Phosphatases; Pyrroles; Thapsigargin; Thrombin; Vanadates | 2001 |
Functionally similar vanadate-induced 8-azidoadenosine 5'-[alpha-(32)P]Diphosphate-trapped transition state intermediates of human P-glycoprotin are generated in the absence and presence of ATP hydrolysis.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Animals; ATP Binding Cassette Transporter, Subfamily B; Azides; Binding Sites; Cell Line; Cell Membrane; HeLa Cells; Humans; Hydrolysis; Insecta; Kinetics; Phosphorus Radioisotopes; Recombinant Proteins; Thermodynamics; Transfection; Vanadates | 2001 |
Modulation of multidrug resistance protein 1 (MRP1/ABCC1) transport and atpase activities by interaction with dietary flavonoids.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Antineoplastic Agents, Phytogenic; ATP-Binding Cassette Transporters; Azides; Binding, Competitive; Biological Transport; Cell Division; Chromatography, High Pressure Liquid; Drug Interactions; Estradiol; Estrogen Antagonists; Flavanones; Flavonoids; Glutathione; HeLa Cells; Humans; Kaempferols; Kinetics; Leukotriene C4; Multidrug Resistance-Associated Proteins; Phosphorus Radioisotopes; Quercetin; Transfection; Tritium; Vanadates; Vincristine | 2001 |
Effect of ionic strength on the conformation of myosin subfragment 1-nucleotide complexes.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Alkylation; Animals; Circular Dichroism; Cysteine; Lysine; Muscle, Skeletal; Myosin Subfragments; Nucleotides; Osmolar Concentration; Potassium; Protein Binding; Protein Conformation; Rabbits; Time Factors; Trinitrobenzenes; Tryptophan; Vanadates | 2001 |
RAFTK/Pyk2 involvement in platelet activation is mediated by phosphoinositide 3-kinase.
Topics: Adenosine Diphosphate; Chromones; Collagen; Enzyme Inhibitors; Fibrinogen; Focal Adhesion Kinase 2; Humans; Intracellular Signaling Peptides and Proteins; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoric Monoester Hydrolases; Phosphorylation; Platelet Activation; Precipitin Tests; Protein Phosphatase 2; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Signal Transduction; Thrombin; Vanadates | 2001 |
Signaling in channel/enzyme multimers: ATPase transitions in SUR module gate ATP-sensitive K+ conductance.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Beryllium; Binding Sites; Electric Conductivity; Enzyme Inhibitors; Fluorides; Guinea Pigs; Hydrolysis; Ion Channel Gating; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Conformation; Receptors, Drug; Recombinant Proteins; Signal Transduction; Sulfonylurea Receptors; Vanadates | 2001 |
Characterization of binding of leukotriene C4 by human multidrug resistance protein 1: evidence of differential interactions with NH2- and COOH-proximal halves of the protein.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Binding Sites; Blotting, Western; Cell Line; Cell Membrane; Cytoplasm; DNA, Complementary; Humans; Hydrolysis; Insecta; Leukotriene C4; Multidrug Resistance-Associated Proteins; Mutation; Photoaffinity Labels; Plasmids; Protein Binding; Protein Structure, Tertiary; Protein Transport; Trypsin; Tumor Cells, Cultured; Vanadates | 2001 |
ATP binding to the first nucleotide-binding domain of multidrug resistance protein MRP1 increases binding and hydrolysis of ATP and trapping of ADP at the second domain.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Allosteric Site; Amino Acid Motifs; Animals; Anions; Aspartic Acid; Blotting, Western; Catalysis; Cell Membrane; Cricetinae; DNA-Binding Proteins; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Hydrolysis; Immunoblotting; Light; Lysine; Mice; Multidrug Resistance-Associated Proteins; Mutation; MutS Homolog 3 Protein; Protein Binding; Protein Structure, Tertiary; Temperature; Vanadates | 2002 |
Nucleotide binding and nucleotide hydrolysis properties of the ABC transporter MRP6 (ABCC6).
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Azides; Beryllium; Cations, Divalent; Fluorescent Dyes; Fluorides; Hydrolysis; Iodine Radioisotopes; Multidrug Resistance-Associated Proteins; Photoaffinity Labels; Pichia; Rats; Recombinant Proteins; Rhodamine 123; Vanadates | 2002 |
Importance of Glu(282) in transmembrane segment M3 of the Na(+),K(+)-ATPase for control of cation interaction and conformational changes.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Catalytic Domain; Enzyme Activation; Enzyme Inhibitors; Glutamic Acid; Isoenzymes; Models, Molecular; Mutagenesis, Site-Directed; Ouabain; Phosphorylation; Potassium; Protein Structure, Tertiary; Rats; Sodium; Sodium-Potassium-Exchanging ATPase; Time Factors; Vanadates | 2002 |
Multiple inequivalent metal-nucleotide coordination environments in the presence of the VO2+-inhibited nitrogenase iron protein: pH-dependent structural rearrangements at the nucleotide binding site.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Binding Sites; Binding, Competitive; Buffers; Crystallography, X-Ray; Deuterium Oxide; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Hydrogen-Ion Concentration; Hydrolysis; Klebsiella pneumoniae; Magnesium; Oxidoreductases; Protein Conformation; Spin Labels; Vanadates; Vanadium Compounds; Water | 2002 |
Vanadate inhibits the ATPase activity and DNA binding capability of bacterial MutS. A structural model for the vanadate-MutS interaction at the Walker A motif.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acid Motifs; Amino Acid Sequence; Bacterial Proteins; DNA; DNA-Binding Proteins; Electrophoretic Mobility Shift Assay; Escherichia coli; Escherichia coli Proteins; Ligands; Models, Molecular; Molecular Sequence Data; MutS DNA Mismatch-Binding Protein; Oligodeoxyribonucleotides; Protein Conformation; Pseudomonas aeruginosa; Scattering, Radiation; Temperature; Vanadates | 2002 |
Dictyostelium myosin II mutations that uncouple the converter swing and ATP hydrolysis cycle.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alanine; Animals; Dictyostelium; Hydrolysis; Isoleucine; Kinetics; Molecular Motor Proteins; Mutagenesis, Site-Directed; Myosin Type II; Myosins; Phenylalanine; Point Mutation; Protozoan Proteins; Vanadates | 2003 |
Temperature and ligand dependence of conformation and helical order in myosin filaments.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Beryllium; Fluorides; Kinetics; Ligands; Models, Chemical; Muscle Fibers, Skeletal; Myosins; Protein Conformation; Protein Structure, Secondary; Rabbits; Temperature; Vanadates | 2003 |
Importance of conserved Thr214 in domain A of the Na+,K+ -ATPase for stabilization of the phosphoryl transition state complex in E2P dephosphorylation.
Topics: Adenosine Diphosphate; Animals; Catalysis; DNA, Complementary; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Phosphorylation; Protein Conformation; Rats; Recombinant Proteins; Sodium-Potassium-Exchanging ATPase; Threonine; Vanadates | 2003 |
Stoichiometry and affinity of nucleotide binding to P-glycoprotein during the catalytic cycle.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Anilino Naphthalenesulfonates; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Catalysis; CHO Cells; Cricetinae; Fluorescent Dyes; Hydrolysis; Protein Binding; Spectrometry, Fluorescence; Trinitrobenzenes; Vanadates | 2003 |
Transition state P-glycoprotein binds drugs and modulators with unchanged affinity, suggesting a concerted transport mechanism.
Topics: Adenosine Diphosphate; Anilino Naphthalenesulfonates; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Benzimidazoles; Biological Transport; CHO Cells; Cobalt; Cricetinae; Dihydropyridines; Doxorubicin; Magnesium; Pharmaceutical Preparations; Photoaffinity Labels; Protein Binding; Spectrometry, Fluorescence; Tryptophan; Vanadates; Vinblastine | 2003 |
Dynein structure and power stroke.
Topics: Adenosine Diphosphate; Animals; Chlamydomonas reinhardtii; Dyneins; Flagella; Microscopy, Electron; Movement; Protein Isoforms; Protein Structure, Tertiary; Structure-Activity Relationship; Vanadates | 2003 |
P-glycoprotein catalytic mechanism: studies of the ADP-vanadate inhibited state.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Amino Acid Substitution; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Catalysis; Catalytic Domain; Dimerization; Hydrolysis; Kinetics; Mice; Protein Conformation; Recombinant Proteins; Vanadates; Verapamil | 2003 |
The allosteric transition of GroEL induced by metal fluoride-ADP complexes.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Allosteric Regulation; Allosteric Site; Aluminum Compounds; Beryllium; Chaperonin 60; Escherichia coli; Fluorides; Gallium; Hydrolysis; Kinetics; Models, Chemical; Mutation; Protein Binding; Protein Conformation; Protein Folding; Pyrenes; Spectrometry, Fluorescence; Vanadates; X-Ray Diffraction | 2003 |
Role of carboxylate residues adjacent to the conserved core Walker B motifs in the catalytic cycle of multidrug resistance protein 1 (ABCC1).
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Motifs; Amino Acid Sequence; Animals; Aspartic Acid; Biological Transport; Carboxylic Acids; Catalysis; Cell Line; Cell Membrane; DNA, Complementary; Drug Resistance, Multiple; Electrophoresis, Polyacrylamide Gel; Glutamic Acid; Humans; Hydrolysis; Insecta; Leukotriene C4; Light; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Mutation; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Sequence Homology, Amino Acid; Time Factors; Vanadates | 2003 |
Prolonged nonhydrolytic interaction of nucleotide with CFTR's NH2-terminal nucleotide binding domain and its role in channel gating.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alanine; Animals; Azides; Cell Line; Chloride Channels; Cystic Fibrosis Transmembrane Conductance Regulator; Humans; Ion Channel Gating; Kinetics; Lysine; Mutation; Oocytes; Osmolar Concentration; Peptide Fragments; Phosphorylation; Protein Isoforms; Protein Structure, Tertiary; Temperature; Time Factors; Vanadates; Xenopus laevis | 2003 |
Synergy between conserved ABC signature Ser residues in P-glycoprotein catalysis.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Alanine; Amino Acid Motifs; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Beryllium; Binding Sites; Catalysis; Charcoal; Dimerization; Dithiothreitol; Dose-Response Relationship, Drug; Fluorides; Humans; Kinetics; Ligands; Lipids; Mice; Mutagenesis; Mutation; Pichia; Protein Binding; Protein Structure, Tertiary; Serine; Temperature; Time Factors; Vanadates | 2004 |
Distinct natures of beryllium fluoride-bound, aluminum fluoride-bound, and magnesium fluoride-bound stable analogues of an ADP-insensitive phosphoenzyme intermediate of sarcoplasmic reticulum Ca2+-ATPase: changes in catalytic and transport sites during ph
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Aluminum Compounds; Animals; Beryllium; Biochemical Phenomena; Biochemistry; Calcimycin; Calcium; Calcium-Transporting ATPases; Catalytic Domain; Cell Membrane; Chelating Agents; Crystallography, X-Ray; Cytoplasm; Dose-Response Relationship, Drug; Fluorides; Hydrogen-Ion Concentration; Hydrolysis; Magnesium Compounds; Models, Chemical; Muscle, Skeletal; Phosphorylation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Rabbits; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Spectrometry, Fluorescence; Thapsigargin; Time Factors; Tryptophan; Vanadates | 2004 |
FITC binding site and p-nitrophenyl phosphatase activity of the Kdp-ATPase of Escherichia coli.
Topics: 4-Nitrophenylphosphatase; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acid Motifs; Amino Acid Sequence; Binding Sites; Cation Transport Proteins; Conserved Sequence; Enzyme Activation; Escherichia coli Proteins; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Lysine; Molecular Sequence Data; Substrate Specificity; Vanadates | 2004 |
Decavanadate binding to a high affinity site near the myosin catalytic centre inhibits F-actin-stimulated myosin ATPase activity.
Topics: Actins; Adenosine Diphosphate; Animals; Binding Sites; Catalytic Domain; Dinucleoside Phosphates; Enzyme Activation; Enzyme Inhibitors; Fluorescence Resonance Energy Transfer; Kinetics; Light; Myosin Subfragments; Myosins; Naphthalenesulfonates; Organometallic Compounds; Protein Conformation; Rabbits; Scattering, Radiation; Vanadates | 2004 |
The nucleotide transporter MRP4 (ABCC4) is highly expressed in human platelets and present in dense granules, indicating a role in mediator storage.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Biological Transport; Blood Platelets; Cyclic GMP; Hermanski-Pudlak Syndrome; Humans; Multidrug Resistance-Associated Proteins; Secretory Vesicles; Vanadates | 2004 |
Properties of P-glycoprotein with mutations in the "catalytic carboxylate" glutamate residues.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Alanine; Animals; Aspartic Acid; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Carboxylic Acids; Catalysis; Dimerization; Dithiothreitol; Dose-Response Relationship, Drug; Glutamic Acid; Hydrolysis; Kinetics; Lipid Metabolism; Lysine; Mice; Models, Chemical; Mutation; Pichia; Protein Conformation; Protein Structure, Tertiary; Time Factors; Vanadates | 2004 |
Multidrug resistance protein 4 (ABCC4)-mediated ATP hydrolysis: effect of transport substrates and characterization of the post-hydrolysis transition state.
Topics: Adenine; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Beryllium; Biological Transport; Catalysis; Cations; Cell Line; Cell Membrane; Chelating Agents; Cobalt; Dinoprostone; DNA, Complementary; Dose-Response Relationship, Drug; Edetic Acid; Fluorides; Humans; Hydrolysis; Insecta; Kinetics; Magnesium; Manganese; Methotrexate; Models, Biological; Multidrug Resistance-Associated Proteins; Nucleotides; Organophosphonates; Protein Binding; Substrate Specificity; Vanadates; Zidovudine | 2004 |
Function-dependent conformational changes of the ABCG2 multidrug transporter modify its interaction with a monoclonal antibody on the cell surface.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Antibodies, Monoclonal; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Benzimidazoles; Catalysis; Cell Line; Cell Membrane; Cell Separation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Humans; Hydrolysis; Immunoblotting; Insecta; Ligands; Mitoxantrone; Mutation; Neoplasm Proteins; Protein Binding; Protein Conformation; Substrate Specificity; Time Factors; Vanadates | 2005 |
Stability of the topoisomerase II closed clamp conformation may influence DNA-stimulated ATP hydrolysis.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Antigens, Neoplasm; DNA; DNA Topoisomerases, Type II; DNA-Binding Proteins; Enzyme Stability; Humans; Hydrolysis; Poly-ADP-Ribose Binding Proteins; Protein Conformation; Razoxane; Vanadates | 2005 |
Structural biology. Flipping lipids: is the third time the charm?
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Motifs; ATP-Binding Cassette Transporters; Bacterial Proteins; Cell Membrane; Crystallography, X-Ray; Dimerization; Electron Spin Resonance Spectroscopy; Escherichia coli; Escherichia coli Proteins; Hydrolysis; Lipid A; Lipid Bilayers; Models, Molecular; Protein Conformation; Protein Folding; Protein Structure, Tertiary; Salmonella typhimurium; Spin Labels; Vanadates | 2005 |
Structure of the ABC transporter MsbA in complex with ADP.vanadate and lipopolysaccharide.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Motifs; ATP-Binding Cassette Transporters; Bacterial Proteins; Binding Sites; Cell Membrane; Crystallography, X-Ray; Cytoplasm; Dimerization; Fourier Analysis; Hydrolysis; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Lipopolysaccharides; Magnesium; Models, Molecular; Periplasm; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Salmonella typhimurium; Substrate Specificity; Vanadates | 2005 |
Characterization of ATP and ADP hydrolysis activity in rat gastric mucosa.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Calcium; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gastric Mucosa; Hydrogen-Ion Concentration; Hydrolysis; In Vitro Techniques; Magnesium; Male; Rats; Rats, Wistar; Sodium Azide; Substrate Specificity; Suramin; Vanadates | 2005 |
Long range allosteric control of cytoplasmic dynein ATPase activity by the stalk and C-terminal domains.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Allosteric Site; Aluminum Compounds; Animals; Chromatography, Ion Exchange; Cytoplasm; Diphosphonates; Dose-Response Relationship, Drug; Dyneins; Electrophoresis, Polyacrylamide Gel; Fluorides; Hydrolysis; Kinetics; Microtubules; Models, Biological; Models, Statistical; Protein Conformation; Protein Structure, Tertiary; Rats; Recombinant Proteins; Solvents; Trypsin; Ultraviolet Rays; Vanadates | 2005 |
Functional importance of three basic residues clustered at the cytosolic interface of transmembrane helix 15 in the multidrug and organic anion transporter MRP1 (ABCC1).
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Sequence; Arginine; Azides; Catalytic Domain; Cell Line; Cytosol; Estradiol; Humans; Kidney; Leukotriene C4; Lysine; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Mutagenesis, Site-Directed; Phosphorus Radioisotopes; Protein Structure, Secondary; Protein Structure, Tertiary; Structure-Activity Relationship; Tritium; Vanadates | 2006 |
Allosteric modulation bypasses the requirement for ATP hydrolysis in regenerating low affinity transition state conformation of human P-glycoprotein.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Allosteric Site; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Binding Sites; Catalytic Domain; Cell Line; Cell Membrane; Flupenthixol; Humans; Hydrolysis; Insecta; Ligands; Molecular Conformation; Prazosin; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Thioxanthenes; Time Factors; Trypsin; Vanadates | 2006 |
Lipopolysaccharide stabilizes the crystal packing of the ABC transporter MsbA.
Topics: Adenosine Diphosphate; ATP-Binding Cassette Transporters; Bacterial Proteins; Crystallization; Crystallography; Crystallography, X-Ray; Escherichia coli; Lipid Metabolism; Lipids; Lipopolysaccharides; Membrane Proteins; Models, Molecular; Protein Conformation; Vanadates | 2005 |
Mitochondrial ATP synthase. Crystal structure of the catalytic F1 unit in a vanadate-induced transition-like state and implications for mechanism.
Topics: Adenosine Diphosphate; Animals; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Magnesium; Male; Mitochondria, Liver; Mitochondrial Proton-Translocating ATPases; Models, Molecular; Protein Conformation; Protein Subunits; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Vanadates | 2006 |
Purification of breast cancer resistance protein ABCG2 and role of arginine-482.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Substitution; Antibodies, Monoclonal; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Cell Membrane; Cloning, Molecular; DNA Primers; Drug Resistance, Multiple; Female; Humans; Kinetics; Mitoxantrone; Mutagenesis, Site-Directed; Neoplasm Proteins; Recombinant Proteins; Vanadates | 2006 |
Sterol transfer by ABCG5 and ABCG8: in vitro assay and reconstitution.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; ATP Binding Cassette Transporter, Subfamily G, Member 5; ATP Binding Cassette Transporter, Subfamily G, Member 8; ATP-Binding Cassette Transporters; Biological Transport; Cholesterol; Dimerization; Lipoproteins; Liposomes; Membrane Fusion; Mice; Recombinant Proteins; Spodoptera; Vanadates | 2006 |
The phosphatase activity of the plasma membrane Ca2+ pump. Activation by acidic lipids in the absence of Ca2+ increases the apparent affinity for Mg2+.
Topics: 4-Nitrophenylphosphatase; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Brain Chemistry; Calcium; Calcium-Transporting ATPases; Cattle; Cell Membrane; Enzyme Activation; Lipids; Magnesium; Phosphates; Phosphatidylcholines; Potassium; Swine; Vanadates | 2007 |
Nucleotide-induced and actin-induced structural changes in SH1-SH2-modified myosin subfragment 1.
Topics: Actins; Actomyosin; Adenosine Diphosphate; Aluminum Compounds; Animals; Beryllium; Calorimetry, Differential Scanning; Electron Spin Resonance Spectroscopy; Fluorides; Myosin Subfragments; Myosins; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Rabbits; Vanadates | 2007 |
Nucleotide dependent packing differences in helical crystals of the ABC transporter MsbA.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; ATP-Binding Cassette Transporters; Bacterial Proteins; Cryoelectron Microscopy; Crystallization; Crystallography; Image Processing, Computer-Assisted; Liposomes; Models, Molecular; Protein Conformation; Recombinant Proteins; Salmonella typhimurium; Vanadates; Vibrio cholerae | 2009 |
Tyrosine phosphorylation by Src within the cavity of the adenine nucleotide translocase 1 regulates ADP/ATP exchange in mitochondria.
Topics: Adenine Nucleotide Translocator 1; Adenosine Diphosphate; Adenosine Triphosphate; Computer Simulation; HeLa Cells; Humans; Hydrogen Peroxide; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Mitochondria; Mitochondrial ADP, ATP Translocases; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Myocardium; Nucleotide Transport Proteins; Phosphorylation; Protein Conformation; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Protein Stability; Protein Structure, Tertiary; Pyrimidines; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; src-Family Kinases; Structure-Activity Relationship; Transfection; Tyrosine; Vanadates | 2010 |
A kinetic assay of mitochondrial ADP-ATP exchange rate in permeabilized cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Beryllium; Cell Line; Citrate (si)-Synthase; Fluorides; Intracellular Membranes; Kinetics; Magnesium; Membrane Potential, Mitochondrial; Mice; Mitochondria; Mitochondrial ADP, ATP Translocases; Myoblasts; Permeability; Proton-Translocating ATPases; Vanadates | 2010 |
Purification, crystallization and preliminary X-ray crystallographic analysis of the ATPase domain of human TAP in nucleotide-free and ADP-, vanadate- and azide-complexed forms.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; ATP Binding Cassette Transporter, Subfamily B, Member 2; ATP-Binding Cassette Transporters; Azides; Crystallization; Crystallography, X-Ray; Humans; Protein Binding; Vanadates | 2012 |
Conserved Walker A cysteines 431 and 1074 in human P-glycoprotein are accessible to thiol-specific agents in the apo and ADP-vanadate trapped conformations.
Topics: Adenosine Diphosphate; Amino Acid Motifs; Amino Acid Sequence; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Conserved Sequence; Cysteine; Humans; Molecular Sequence Data; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Substrate Specificity; Sulfhydryl Compounds; Vanadates | 2013 |
Measurement of ADP-ATP exchange in relation to mitochondrial transmembrane potential and oxygen consumption.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Beryllium; Biochemistry; Calibration; Cell Respiration; Cells, Cultured; Fluorides; Glycine; Humans; Membrane Potential, Mitochondrial; Mice; Oxygen; Vanadates; Xanthenes | 2014 |
Kinetic validation of the models for P-glycoprotein ATP hydrolysis and vanadate-induced trapping. Proposal for additional steps.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Algorithms; ATP Binding Cassette Transporter, Subfamily B; Catalysis; Hydrolysis; Kinetics; Models, Biological; Protein Binding; Reproducibility of Results; Vanadates | 2014 |
KdpFABC reconstituted in Escherichia coli lipid vesicles: substrate dependence of the transport rate.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Cation Transport Proteins; Cytoplasm; Enzyme Inhibitors; Escherichia coli; Escherichia coli Proteins; Ion Transport; Kinetics; Liposomes; Magnesium; Phosphates; Potassium; Thermodynamics; Vanadates | 2014 |
Characterization of E-NTPDase (EC 3.6.1.5) activity in hepatic lymphocytes: A different activity profile from peripheral lymphocytes.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Blood Cells; Calcium; Cations, Divalent; Cell Separation; Enzyme Assays; Enzyme Inhibitors; Gene Expression; Hydrogen-Ion Concentration; Kinetics; Liver; Lymphocytes; Male; Organ Specificity; Ouabain; Rats; Rats, Wistar; Sodium Azide; Substrate Specificity; Suramin; Vanadates | 2017 |
Structure and analysis of nucleoside diphosphate kinase from Borrelia burgdorferi prepared in a transition-state complex with ADP and vanadate moieties.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Animals; Binding Sites; Borrelia burgdorferi; Female; Mice; Mice, Inbred C3H; Nucleoside-Diphosphate Kinase; Protein Structure, Secondary; Protein Structure, Tertiary; Vanadates | 2018 |
Inhibition and stimulation of the human breast cancer resistance protein as in vitro predictor of drug-drug interactions of drugs of abuse.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; ATP Binding Cassette Transporter, Subfamily G, Member 2; Drug Interactions; Humans; Illicit Drugs; Neoplasm Proteins; Rosuvastatin Calcium; Sulfasalazine; Vanadates | 2018 |
Conformation space of a heterodimeric ABC exporter under turnover conditions.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; ATP-Binding Cassette Transporters; Cryoelectron Microscopy; Hydrolysis; Kinetics; Models, Molecular; Mutation; Protein Conformation; Protein Multimerization; Substrate Specificity; Thermus thermophilus; Vanadates | 2019 |
Cryo-EM structure of MsbA in saposin-lipid nanoparticles (Salipro) provides insights into nucleotide coordination.
Topics: Adenosine Diphosphate; Bacterial Proteins; Cryoelectron Microscopy; Liposomes; Nanoparticles; Saposins; Vanadates | 2022 |