adenosine diphosphate has been researched along with thromboxanes in 130 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 93 (71.54) | 18.7374 |
| 1990's | 16 (12.31) | 18.2507 |
| 2000's | 9 (6.92) | 29.6817 |
| 2010's | 7 (5.38) | 24.3611 |
| 2020's | 5 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Chignard, M; Vargaftig, BB | 1 |
| Cagle, WD; Lord, J; Lucky, W; Maruta, H; Ziboh, VA | 1 |
| Patscheke, H | 1 |
| Gerrard, JM; White, JG | 1 |
| Gorman, RR; Miller, OV; Wierenga, W | 1 |
| Ferrendelli, JA; Minkes, MS; Needleman, P; Raz, A; Sprecher, H | 1 |
| Burns, TS; Saunders, RN | 1 |
| Enke, SE; Halushka, PV; Le Breton, GC; Venton, DL | 1 |
| Chytkowski, A; Dembinska-Kiec, A; Gryglewski, RJ; Zmuda, A | 1 |
| Folco, G; Granström, E; Kindahl, H; Malmsten, C; Samuelsson, B | 1 |
| Grodzińska, L; Marcinkiewicz, E | 1 |
| Harada, Y; Katori, M; Tanaka, K | 1 |
| Grant, B; Katz, J; Lindner, C; Meyers, KM | 1 |
| Holmsen, H; Meyers, KM; Prieur, DJ; Seachord, CL; Smith, JB | 1 |
| Gryglewski, RJ; Moncada, S; Salmon, JA; Ubatuba, FB; Vane, JR; Weatherly, BC | 1 |
| Mashimo, N; Mitani, J; Numano, F; Sakurada, H; Watanabe, Y; Yamaguchi, S | 1 |
| Bailey, JM; Makheja, AN; Vanderhoek, JY | 1 |
| Gries, FA; Homberg, M; Roesen, P; Tschoepe, D | 1 |
| Chi, LG; Kitzen, JM; Lucchesi, BR; Uprichard, AC | 1 |
| Aznar, J; Broekman, MJ; Marcus, AJ; Martinez-Sales, V; Portoles, M; Safier, LB; Santos, MT; Valles, J | 1 |
| Hohlfeld, T; Schrör, K; Weber, A | 1 |
| Böshagen, H; Fiedler, VB; Perzborn, E; Rosentreter, U; Sander, E; Seuter, F; Stasch, JP; Weber, H | 1 |
| Fujitani, B; Wakitani, K | 1 |
| Brace, LD; Le Breton, GC; Venton, DL | 2 |
| Caprino, L; Gallozzi, S; Togna, G | 1 |
| Cheng, KL; Huang, TF; Ko, FN; Lin, CN; Teng, CM | 1 |
| Cerbone, AM; Cirillo, F; Di Minno, G; Mancini, M; Mattioli, PL; Pannain, M; Postiglione, A | 1 |
| Eldor, A; Heyns, Adu P; Marx, G; Yarom, R | 1 |
| Halushka, PV; Kochel, PJ; Mais, DE; Saussy, DL | 1 |
| Cragoe, EJ; Johnson, SL; Limbird, LE; Sweatt, JD | 1 |
| Shapiro, SS | 1 |
| Frölich, JC; Küster, LJ | 1 |
| Akkerman, JW; Kloprogge, E | 1 |
| Boinot, C; Caen, J; Launay, JM; Levy-Toledano, S; Maclouf, J; Rendu, F; Tanzer, J | 1 |
| Zahavi, J; Zahavi, M | 1 |
| Cerbone, AM; Di Minno, G; Iride, C; Mancini, M; Mattioli, PL; Postiglione, A | 1 |
| Altieri, DC; Mannucci, PM | 1 |
| Houston, DS; Vanhoutte, PM | 1 |
| Darius, H; Schrör, K | 1 |
| Caprino, L; Cebo, B; Dolci, N; Tempesta, E; Togna, AR; Togna, G | 1 |
| Atkinson, PM; Bradlow, BA; Chetty, N | 1 |
| Bernini, W; De Caterina, R; Gazzetti, P; Giannessi, D | 1 |
| Boney, CM; Jones, JB; McDonald, TP | 1 |
| Ditter, H; Lasch, HG; Matthias, FR | 1 |
| Darcet, P; Dechavanne, M; Driss, F; Lagarde, M; Vericel, E | 1 |
| D'Angelo, A; Galli, G; Mannucci, PM; Pareti, FI; Sautebin, L; Smith, JB | 1 |
| Chignard, M; Dumarey, C; Fouque, F; Vargaftig, BB | 1 |
| Born, GV; Shafi, S; Thorngren, M | 1 |
| Martin, TJ; Smith, IL | 1 |
| Benveniste, J; Fouque, F; Joseph, D; Odiot, J; Vargaftig, BB | 1 |
| Colombo, C; Galli, C; Socini, A; Tremoli, E | 1 |
| Best, LC; Bone, EA; Jones, PB; Russell, RG | 1 |
| Bennett, JS; Burch, JW; Vilaire, G | 1 |
| Ghali, NI; Hung, SC; Le Breton, GC; Venton, DL | 1 |
| Fujita, T; Hamazaki, T; Hirai, A; Kondo, S; Kumagai, A; Miyamoto, T; Ozawa, A; Sajiki, J; Tamura, Y; Terano, T | 1 |
| Hillbom, M; Kangasaho, M; Kaste, M; Vapaatalo, H; Wuorela, H | 1 |
| Le Breton, GC; Parise, LV; Venton, DL | 2 |
| Burns, GB; Dodge, JA | 1 |
| Brash, AR; FitzGerald, GA; Hawiger, J; Lawson, JA; Maas, RL; Oates, JA; Roberts, LJ | 1 |
| Borda, ES; Gimeno, AL; Gimeno, MF; Lazzari, MA; Sterin-Borda, L | 1 |
| Riecker, G | 1 |
| Barbero, M; Benedetto, C; Massobrio, M; Petitti, E; Rey, L; Slater, TF; Tavella, AM | 1 |
| Catalano, PM; De Marco, L; Di Minno, G; Murphy, S; Shapiro, SS | 1 |
| Barradas, MA; Dandona, P; Green, N; Jeremy, JY; Mikhailidis, DP | 1 |
| Dahl, ML; Matintalo, M; Uotila, P | 1 |
| Chan, CC; Ford-Hutchinson, AW; Hall, RA; Nathaniel, DJ; Yusko, PJ | 1 |
| Holmsen, H; Rao, AK; Willis, J | 1 |
| Gachályi, B; Káldor, A; Tihanyi, K; Vas, A | 1 |
| Colman, RW; Rao, AK; Sinha, AK; Willis, J | 1 |
| Eldor, A; Floman, Y; Liebergall, M; Robin, GC | 1 |
| Kangasaho, M; Vapaatalo, H | 1 |
| Mehta, J; Mehta, P; Ostrowski, N | 1 |
| Davì, G; Fiore, M; Foderà, A; Mattina, A; Mazzola, A; Novo, S; Strano, A | 1 |
| Berman, W; Friedman, Z | 1 |
| Cowan, DH | 1 |
| Haanen, C; Imandt, L; Thomas, C; Tijhuis, D; van den Berg, R; Wessels, H | 1 |
| Christea, C; Herberg, LL; Landgraf, R; Landgraf-Leurs, MM; Loy, A; Siess, W; Weber, PC | 1 |
| Cornwell, DG; Karpen, CW; Merola, AJ; Panganamala, RV; Trewyn, RW | 1 |
| Harris, RH; Nichols, R; Ramwell, PW; Schmeling, JW | 1 |
| Grimm, LJ; Halushka, PV; Knapp, DR; Senator, D | 1 |
| Lewis, GP; Watts, IS | 1 |
| Brown, CB; Greaves, M; Jackson, CA; Patterson, AD; Preston, FE | 1 |
| Herberg, LL; Landgraf, R; Landgraf-Leurs, MM; Loy, A; Weber, PC | 1 |
| Jones, PB; Leach, E; Martin, JF; Suggett, AJ | 1 |
| Benton, AM; Gerrard, JM; Kindom, SE; Michiel, T | 1 |
| Araki, H; Lefer, AM; Smith, JB | 1 |
| Benveniste, J; Chignard, M; Vargaftig, BB | 1 |
| Roth, P; Siess, W; Weber, PC | 1 |
| Fletcher, JR; Harris, RH; Ramwell, PW; Schmeling, JW | 1 |
| Vargaftig, BB | 1 |
| Fiedel, BA; Izzi, JM; Prancan, A; Simpson, RM | 1 |
| Hillbom, M; Kangasaho, M; Kaste, M; Vapaatalo, H | 1 |
| Best, LC; Jones, PB; Russell, RG | 1 |
| Deutsch, E; Mörz, R | 1 |
| Lorenz, R; Siess, W; Weber, PC | 1 |
| Anderson, WH; Chuang, HY; Mason, RG; Mohammad, SF; Smith, JB | 1 |
| Gerrard, JM; Rao, GH; White, JG; Witkop, CJ | 1 |
| Schrör, K | 1 |
| Hohlfeld, T; Schrör, K; Strobach, H; Weber, AA | 1 |
| Anfossi, G; Cavalot, F; Massucco, P; Mattiello, L; Mularoni, EM; Parisi, S; Russo, I; Trovati, M | 1 |
| Daniel, JL; Gazzaniga, PP; Pulcinelli, FM; Riondino, S; Salganicoff, L | 1 |
| Bretschneider, E; Glusa, E; Schrör, K | 1 |
| Kuo, YH; Lin, CH; Lin, YL; Teng, CM | 1 |
| Schrör, K; Verheggen, R | 1 |
| Buring, JE; Hennekens, CH; Lipinska, I; Ridker, PM; Tofler, GH | 1 |
| Hillbom, M; Juvela, S; Numminen, H | 1 |
| Blache, D; Durand, P; Lussier-Cacan, S | 1 |
| Hohlfeld, T; Liesener, S; Schanz, A; Schrör, K; Weber, AA | 1 |
| Baggiolini, M; Clemetson, JM; Clemetson, KJ; Power, CA; Proudfoot, AE; Wells, TN | 1 |
| Atkinson, BT; Pears, CJ; Stafford, MJ; Watson, SP | 1 |
| Balduini, C; Bertoni, A; Campus, F; Lova, P; Sinigaglia, F; Torti, M | 1 |
| Dobaczewski, M; Golanski, J; Kazmierczak, P; Lapshina, E; Markuszewski, L; Nocun, M; Watala, C; Zavodnik, I; Zavodnik, L | 1 |
| Barton, JF; Hardy, AR; Mundell, SJ; Poole, AW | 1 |
| Becker, RC; Conley, PB; French, PA; Gachet, C; Goodman, SG; Kuliopulos, A; Moliterno, DJ; Roe, MT; Smyth, SS; Steinhubl, SR; Weitz, JI; Woulfe, DS | 1 |
| Bhavaraju, K; Bynagari, YS; Kim, S; Kunapuli, SP; Nagy, B; Tuluc, F; Vijayan, KV | 1 |
| Naidu, KA; Raghavendra, RH | 1 |
| Hu, H; Huang, ZS; Jiang, L; Li, N; Zeng, CL; Zhu, LJ | 1 |
| Goloborodova, IV; Lavrenova, NIu; Sokolov, EI | 1 |
| Bounameaux, H; Cairols, MA; Clement, DL; Coccheri, S; Fiessinger, JN; Fletcher, JP; Hoffmann, U; Turpie, AG | 1 |
| Bhavaraju, K; Gartner, TK; Georgakis, A; Jin, J; Kunapuli, SP; Nurden, A; Nurden, P; Tomiyama, Y | 1 |
| Bangsbo, J; Hansen, AH; Hellsten, Y; Nyberg, M; Saltin, B | 1 |
| Bhavaraju, K; Bynagari-Settipalli, YS; Jin, J; Kim, S; Kunapuli, SP; Lakhani, P; Rico, MC; Woulfe, D | 1 |
| Aberg, JA; Berger, JS; Bhardwaj, N; Cavanagh, K; Gettenberg, G; Hu, L; Merolla, M; Montenont, E; Nardi, MA; O'Brien, M; Valdes, V | 1 |
| Cardoso, CAL; Freitas de Lima, F; Lescano, CH; Mónica, FZ; Pires de Oliveira, I; Vieira, SCH | 1 |
| Böhm, A; Grammbauer, S; Greinacher, A; Hafkemeyer, A; Hasan, M; Jedlitschky, G; Moritz, E; Palankar, R; Rauch, BH; Tolksdorf, C; Tzvetkov, MV; Wolf, R | 1 |
| Barrs, VR; Griebsch, C; Hall, E | 1 |
| Fuentes, E; Palomo, I; Rodríguez, L; Trostchansky, A; Vogel, H; Wehinger, S; Wood, I | 1 |
| Cheung, SS; Hellsten, Y; Lundberg Slingsby, MH; Nørregaard, LB; Wickham, KA | 1 |
9 review(s) available for adenosine diphosphate and thromboxanes
| Article | Year |
|---|---|
Prostaglandins and thromboxanes: "middlemen" modulating platelet function in hemostasis and thrombosis.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acids; Arteriosclerosis; Blood Coagulation; Blood Platelets; Calcium; Cyclic AMP; Hemostasis; Humans; Prostaglandins; Prostaglandins G; Prostaglandins H; Rats; Thrombosis; Thromboxane A2; Thromboxanes | 1978 |
Prostaglandins and thromboxanes: biochemical and physiological considerations.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acids; Blood Platelets; Humans; Muscle Contraction; Muscle, Smooth; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandins; Thromboxanes | 1978 |
Characterisation of factor VIII receptors.
Topics: Adenosine Diphosphate; Asialoglycoproteins; Blood Platelets; Drug Synergism; Epinephrine; Glycoproteins; Humans; Immunologic Techniques; Macromolecular Substances; Membrane Proteins; Molecular Weight; Platelet Aggregation; Platelet Glycoprotein GPIb-IX Complex; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Ristocetin; Thromboxanes; von Willebrand Factor | 1985 |
Hematologic effects of prostaglandins and thromboxanes and inhibitors of their synthesis in the perinatal period.
Topics: Adenosine Diphosphate; Animals; Blood Cells; Blood Platelets; Cyclooxygenase Inhibitors; Epoprostenol; Erythrocytes; Fatty Acids, Essential; Female; Fetus; Humans; Infant, Newborn; Labor, Obstetric; Macrophages; Neutrophils; Phagocytes; Phospholipases; Pregnancy; Prostaglandin Antagonists; Prostaglandins; Thromboxane-A Synthase; Thromboxanes | 1980 |
Thromboxane A2, prostacyclin and aspirin: effects on vascular tone and platelet aggregation.
Topics: Adenosine Diphosphate; Animals; Aspirin; Blood Vessels; Cats; Coronary Vessels; Epoprostenol; Guinea Pigs; Humans; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandins; Prostaglandins E; Prostaglandins F; Rabbits; Thromboxane A2; Thromboxanes | 1980 |
Present concepts on the mechanisms of platelet aggregation.
Topics: Adenosine Diphosphate; Animals; Carrageenan; Crotalid Venoms; Humans; Lectins, C-Type; Lysophosphatidylcholines; Membrane Lipids; Phospholipases A; Platelet Activating Factor; Platelet Aggregation; Thromboxanes; Type C Phospholipases | 1981 |
Antiplatelet drugs. A comparative review.
Topics: Adenosine Diphosphate; Animals; Aspirin; Base Sequence; Blood Platelets; Consensus Sequence; Humans; Molecular Sequence Data; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIb-IX Complex; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Thrombin; Thrombosis; Thromboxanes | 1995 |
G-protein-coupled receptors as signaling targets for antiplatelet therapy.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Drug Design; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Receptor, PAR-1; Receptors, G-Protein-Coupled; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Receptors, Thrombin; Receptors, Thromboxane; Signal Transduction; Thrombin; Thromboxanes | 2009 |
A Comprehensive Literature Review on Cardioprotective Effects of Bioactive Compounds Present in Fruits of
Topics: Adenosine Diphosphate; Anthocyanins; Antioxidants; Elaeocarpaceae; Flavonoids; Fruit; Glucose; Plant Extracts; Platelet Aggregation Inhibitors; Polyphenols; Thrombin; Thromboxanes | 2022 |
6 trial(s) available for adenosine diphosphate and thromboxanes
| Article | Year |
|---|---|
Reduced platelet thromboxane formation after long-term administration of a dihydropyridine calcium channel blocker: a prospective, double-blind, placebo-controlled study with nitrendipine in borderline hypertensive patients with IDDM-type diabetes mellitu
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Collagen; Diabetes Mellitus, Type 1; Double-Blind Method; Female; Humans; Hypertension; In Vitro Techniques; Male; Nitrendipine; Physical Exertion; Placebos; Platelet Aggregation; Prospective Studies; Thromboxanes | 1992 |
Inhibition of platelet aggregation and thromboxane synthesis after intake of small amount of icosapentaenoic acid.
Topics: Adenosine Diphosphate; Aged; Arachidonic Acids; Blood Platelets; Chromatography, Gas; Chromatography, High Pressure Liquid; Collagen; Eicosapentaenoic Acid; Epinephrine; Fatty Acids, Unsaturated; Humans; Hydroxyeicosatetraenoic Acids; Lipids; Male; Middle Aged; Phosphatidylcholines; Phospholipids; Platelet Aggregation; Thromboxane A2; Thromboxane B2; Thromboxanes | 1984 |
Anti-platelet effects of 100 mg alternate day oral aspirin: a randomized, double-blind, placebo-controlled trial of regular and enteric coated formulations in men and women.
Topics: Adenosine Diphosphate; Administration, Oral; Adult; Arachidonic Acid; Aspirin; Blood Platelets; Cardiovascular Diseases; Double-Blind Method; Drug Administration Schedule; Epinephrine; Epoprostenol; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Radioimmunoassay; Risk Factors; Thromboxanes | 1996 |
Thromboxane Antagonism with terutroban in Peripheral Arterial Disease: the TAIPAD study.
Topics: Adenosine Diphosphate; Adult; Aged; Aspirin; Blood Pressure; Double-Blind Method; Female; Humans; Male; Middle Aged; Naphthalenes; Peripheral Arterial Disease; Placebos; Platelet Aggregation; Propionates; Thromboxanes; Time Factors | 2010 |
Antagonism of P2Y₁₂ reduces physiological thromboxane levels.
Topics: Adenosine Diphosphate; Adolescent; Adult; Animals; Blood Platelets; Clopidogrel; Female; Humans; Male; Mice; Mice, Knockout; Middle Aged; Pilot Projects; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Thiophenes; Thromboxanes; Ticlopidine; Young Adult | 2010 |
Aspirin attenuates platelet activation and immune activation in HIV-1-infected subjects on antiretroviral therapy: a pilot study.
Topics: Adenosine Diphosphate; Adult; Aged; Anti-HIV Agents; Arachidonic Acid; Aspirin; Cells, Cultured; Collagen; Female; HIV Infections; HIV-1; Humans; Inflammation; Lymphocyte Activation; Male; Middle Aged; P-Selectin; Pilot Projects; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Thromboxanes; Young Adult | 2013 |
115 other study(ies) available for adenosine diphosphate and thromboxanes
| Article | Year |
|---|---|
Why do some beta adrenergic agonists inhibit generation of thromboxane A2 in incubates of platelets with arachidonic acid?
Topics: Adenosine Diphosphate; Adrenergic beta-Agonists; Albuterol; Animals; Arachidonic Acids; Blood Platelets; Dogs; In Vitro Techniques; Isoproterenol; Lidocaine; Platelet Aggregation; Thromboxane A2; Thromboxanes | 1978 |
Increased biosynthesis of thromboxane A2 by diabetic platelets.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acids; Blood Platelets; Diabetes Mellitus; Female; Humans; Male; Middle Aged; Pregnancy; Pregnancy in Diabetics; Thromboxane A2; Thromboxanes | 1979 |
Correlation of activation and aggregation of platelets. Discrimination between anti-activating and anti-aggregating agents.
Topics: Adenosine Diphosphate; Blood Platelets; Calcium; Edetic Acid; Humans; In Vitro Techniques; Indomethacin; Platelet Aggregation; Prostaglandin Endoperoxides; Sialic Acids; Temperature; Thromboxanes | 1979 |
Independence of the cyclic AMP-lowering activity of thromboxane A2 from the platelet release reaction.
Topics: Adenosine Diphosphate; Blood Platelets; Calcium; Cyclic AMP; Egtazic Acid; Epoprostenol; Gallic Acid; Humans; Models, Biological; Platelet Aggregation; Prostaglandins H; Serotonin; Thromboxane A2; Thromboxane B2; Thromboxanes | 1979 |
Triene prostaglandins: prostacyclin and thromboxane biosynthesis and unique biological properties.
Topics: Adenosine Diphosphate; Arachidonic Acids; Blood Platelets; Cyclic AMP; Eicosanoic Acids; Epoprostenol; Phospholipases; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Prostaglandins H; Thromboxanes | 1979 |
Antiplatelet activity of hydralazine.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acids; Blood Platelets; Calcium; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Hydralazine; Male; Platelet Aggregation; Rats; Thromboxanes | 1979 |
13-Azaprostanoic acid: a specific antagonist of the human blood platelet thromboxane/endoperoxide receptor.
Topics: Adenosine Diphosphate; Blood Platelets; Fatty Acids; Humans; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandins H; Prostanoic Acids; Receptors, Drug; Serotonin; Thrombin; Thromboxane A2; Thromboxane B2; Thromboxanes | 1979 |
Experimental atherosclerosis in rabbits: platelet aggregation, thromboxane A2 generation and anti-aggregatory potency of prostacyclin.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acids; Arteriosclerosis; Epoprostenol; Platelet Aggregation; Prostaglandins; Rabbits; Thromboxane A2; Thromboxanes | 1977 |
The generation of TXA2 in human platelet rich plasma and its inhibition by nictindole and prostacyclin.
Topics: Adenosine Diphosphate; Arachidonic Acids; Blood Platelets; Collagen; Epinephrine; Epoprostenol; Humans; In Vitro Techniques; Indoles; Oxidoreductases; Platelet Aggregation; Prostaglandins; Pyridines; Thrombin; Thromboxane A2; Thromboxane-A Synthase; Thromboxanes | 1979 |
EG-626: not a thromboxane A2 antagonist, but a PGI2 potentiator in platelet aggregation.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acids; Collagen; Drug Synergism; Epoprostenol; Phthalazines; Platelet Aggregation; Prostaglandins; Pyridazines; Rabbits; Thromboxane A2; Thromboxanes | 1979 |
Phenylbutazone inhibition of equine platelet function.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acids; Aspirin; Blood Platelets; Collagen; Horses; Malondialdehyde; Phenylbutazone; Platelet Aggregation; Prostaglandins; Thrombin; Thromboxanes | 1979 |
A dominant role of thromboxane formation in secondary aggregation of platelets.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acids; Blood Platelets; Cats; Chediak-Higashi Syndrome; Indomethacin; Platelet Aggregation; Serotonin; Thromboxane A2; Thromboxane B2; Thromboxanes | 1979 |
Effects of all cis-5,8,11,14,17 eicosapentaenoic acid and PGH3 on platelet aggregation.
Topics: Adenosine Diphosphate; Arachidonic Acids; Collagen; Drug Interactions; Eicosanoic Acids; Fatty Acids, Unsaturated; Feeding Behavior; Humans; Inuit; Linoleic Acids; Linolenic Acids; Myocardial Infarction; Oleic Acids; Platelet Aggregation; Prostaglandins D; Prostaglandins E; Prostaglandins F, Synthetic; Thromboxanes | 1979 |
[Role of thromboxane A2 in platelet aggregation. Preliminary report].
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adult; Blood Platelets; Collagen; Epinephrine; Humans; In Vitro Techniques; Male; Nucleotides, Cyclic; Platelet Aggregation; Thromboxane A2; Thromboxanes | 1979 |
Effects of onion (Allium cepa) extract on platelet aggregation and thromboxane synthesis.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acids; Blood Platelets; Female; Humans; In Vitro Techniques; Magnoliopsida; Male; Platelet Aggregation; Rabbits; Thromboxane B2; Thromboxanes | 1979 |
Effects of combined thromboxane synthetase inhibition/thromboxane receptor antagonism in two models of sudden cardiac death in the canine: limited role for thromboxane.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Arrhythmias, Cardiac; Collagen; Coronary Disease; Death, Sudden; Disease Models, Animal; Dogs; Electric Stimulation; Electrophysiology; Female; Heart Rate; Male; Pentanoic Acids; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Pyridines; Receptors, Prostaglandin; Receptors, Thromboxane; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes | 1990 |
Erythrocytes metabolically enhance collagen-induced platelet responsiveness via increased thromboxane production, adenosine diphosphate release, and recruitment.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adult; Aspirin; beta-Thromboglobulin; Blood Platelets; Collagen; Erythrocytes; Female; Humans; Male; Middle Aged; P-Selectin; Platelet Membrane Glycoproteins; Serotonin; Thromboxane A2; Thromboxane B2; Thromboxanes | 1991 |
ADP-induced second wave aggregation in platelet rich plasma from hypercholesterolemic rabbits.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Hypercholesterolemia; Lipids; Male; Platelet Aggregation; Rabbits; Thromboxanes | 1991 |
Characterization of Bay U 3405, a novel thromboxane A2/endoperoxide receptor antagonist.
Topics: Adenosine Diphosphate; Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Binding, Competitive; Carbazoles; Cerebrovascular Disorders; Collagen; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Rats; Rats, Inbred SHR; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfonamides; Thromboembolism; Thromboxanes; Vasoconstriction | 1990 |
Studies on antiplatelet effects of OP-41483, a prostaglandin I2 analog, in experimental animals. II. Mechanism of its antiplatelet effect.
Topics: Adenosine Diphosphate; Adenylyl Cyclases; Animals; Binding, Competitive; Blood Platelets; Calcium; Cyclic AMP; Dideoxyadenosine; Epoprostenol; Guinea Pigs; In Vitro Techniques; Male; Microsomes; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombin; Thromboxanes | 1990 |
Reversal of thromboxane A2/prostaglandin H2 and ADP-induced calcium release in intact platelets.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcium; Chlortetracycline; Cyclic AMP; Epoprostenol; Humans; Ion Channels; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Prostanoic Acids; Stimulation, Chemical; Thromboxane A2; Thromboxanes | 1985 |
Influence of strontium chloride on blood platelet function.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcium; Collagen; In Vitro Techniques; Nephelometry and Turbidimetry; Platelet Aggregation; Rabbits; Strontium; Thromboxane A2; Thromboxane B2; Thromboxanes | 1989 |
Novel inhibitory actions on platelet thromboxane and inositolphosphate formation by xanthones and their glycosides.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Collagen; Glycosides; Inositol Phosphates; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Structure-Activity Relationship; Thrombin; Thromboxanes; Xanthenes; Xanthones | 1989 |
Thromboxane- and ADP-independent aggregation and exposure of fibrinogen receptors on platelets from patients with familial hypercholesterolemia.
Topics: Adenosine Diphosphate; Adolescent; Adult; Apyrase; Aspirin; Child; Female; Humans; Hyperlipoproteinemia Type II; Male; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Thromboxanes | 1985 |
Zinc-induced platelet aggregation is mediated by the fibrinogen receptor and is not accompanied by release or by thromboxane synthesis.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Blood Platelet Disorders; Blood Platelets; Calcium; Collagen; Copper; Epoprostenol; Glycoproteins; Heparin; Humans; Manganese; Membrane Proteins; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Serotonin; Thromboxane A2; Thromboxanes; Zinc | 1985 |
Binding of an 125I-labeled thromboxane A2/prostaglandin H2 receptor antagonist to washed canine platelets.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Dogs; Epinephrine; Hydrogen-Ion Concentration; Kinetics; Prostaglandin Endoperoxides, Synthetic; Receptors, Cell Surface; Receptors, Prostaglandin; Receptors, Thromboxane; Receptors, Thromboxane A2, Prostaglandin H2; Structure-Activity Relationship; Thromboxane A2; Thromboxanes | 1985 |
Inhibitors of Na+/H+ exchange block stimulus-provoked arachidonic acid release in human platelets. Selective effects on platelet activation by epinephrine, ADP, and lower concentrations of thrombin.
Topics: Adenosine Diphosphate; Amiloride; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Carrier Proteins; Epinephrine; Humans; Hydrogen-Ion Concentration; Male; Platelet Aggregation; Serotonin; Sodium; Sodium-Hydrogen Exchangers; Thrombin; Thromboxanes | 1985 |
Platelet aggregation and thromboxane release induced by arachidonic acid, collagen, ADP and platelet-activating factor following low dose acetylsalicylic acid in man.
Topics: Adenosine Diphosphate; Adolescent; Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Collagen; Dose-Response Relationship, Drug; Female; Humans; Male; Platelet Activating Factor; Platelet Aggregation; Thromboxane B2; Thromboxanes | 1986 |
Platelet-activating factor (PAF-acether) induces high- and low-affinity binding of fibrinogen to human platelets via independent mechanisms.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Fibrinogen; Humans; Indomethacin; Kinetics; Macromolecular Substances; Platelet Activating Factor; Prostaglandin Endoperoxides; Protein Binding; Thromboxanes | 1986 |
Hermansky-Pudlak platelets: further studies on release reaction and protein phosphorylations.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adolescent; Albinism; Blood Platelet Disorders; Blood Platelets; Calcimycin; Drug Synergism; Humans; Male; Phosphorylation; Platelet Aggregation; Platelet Storage Pool Deficiency; Serotonin; Syndrome; Thrombin; Thromboxanes | 1987 |
Enhanced platelet release reaction, shortened platelet survival time and increased platelet aggregation and plasma thromboxane B2 in chronic obstructive arterial disease.
Topics: Adenosine Diphosphate; Aged; Arterial Occlusive Diseases; beta-Thromboglobulin; Blood Platelets; Cell Survival; Epinephrine; Epoprostenol; Female; Humans; In Vitro Techniques; Male; Middle Aged; Platelet Aggregation; Thromboxane B2; Thromboxanes | 1985 |
Platelet fibrinogen binding in familial hypercholesterolemia.
Topics: Adenosine Diphosphate; Adolescent; Adult; Blood Platelets; Child; Female; Fibrinogen; Humans; Hyperlipoproteinemia Type II; Male; Platelet Aggregation; Platelet Membrane Glycoproteins; Protein Binding; Thromboxanes; Ticlopidine | 1987 |
Thromboxane generation by human monocytes enhances platelet function.
Topics: Adenosine Diphosphate; Blood Platelets; Fibrinogen; Humans; Indomethacin; Monocytes; Platelet Aggregation; Thromboxanes | 1986 |
Platelets, endothelium, and vasospasm.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Dinoprost; Endothelium; Humans; Platelet Activating Factor; Platelet Aggregation; Prostaglandins F; Serotonin; Thromboxanes; Vasoconstriction | 1985 |
The action of flupirtine on prostaglandin formation and platelet aggregation in vitro.
Topics: Adenosine Diphosphate; Aminopyridines; Analgesics; Anesthetics, Local; Animals; Aorta, Thoracic; Epoprostenol; Female; Guinea Pigs; Humans; In Vitro Techniques; Indomethacin; Muscle, Smooth, Vascular; Myocardial Contraction; Platelet Aggregation; Prostaglandins; Rabbits; Rats; Rats, Inbred Strains; Thromboxanes | 1985 |
Platelet responsiveness and biosynthesis of thromboxane and prostacyclin in response to in vitro cocaine treatment.
Topics: Adenosine Diphosphate; Animals; Aorta, Abdominal; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcium; Cocaine; Collagen; Dose-Response Relationship, Drug; Epoprostenol; Male; Platelet Aggregation; Rabbits; Rats; Thromboxanes | 1985 |
Thromboxane A2/prostaglandin H2 mobilizes calcium in human blood platelets.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcium; Chlortetracycline; Epoprostenol; Humans; Indomethacin; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Prostanoic Acids; Stimulation, Chemical; Thromboxane A2; Thromboxanes | 1985 |
Long-term ultra-low-dose aspirin therapy and platelet function.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Bleeding Time; Collagen; Dose-Response Relationship, Drug; Epinephrine; Female; Humans; Male; Platelet Aggregation; Thromboxane B2; Thromboxanes; Time Factors | 1985 |
Inhibition of platelet aggregation and thromboxane B2 production during aspirin treatment: dependence on the dose of the aggregating agent.
Topics: Adenosine Diphosphate; Adult; Aspirin; Blood Platelets; Dose-Response Relationship, Drug; Epinephrine; Female; Humans; Male; Platelet Aggregation; Thromboxane B2; Thromboxanes | 1985 |
Abnormal function and thromboxane release from platelets of dogs with cyclic hematopoiesis.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Collagen; Dog Diseases; Dogs; Female; Hematopoietic System; Heterozygote; Male; Neutropenia; Platelet Aggregation; Thromboxanes | 1985 |
Comparison of sympathomimetic amines with collagen, calcium ionophor and adenosine diphosphate in their effects on thromboxane formation of human platelet rich plasma.
Topics: Adenosine Diphosphate; Blood Platelets; Calcimycin; Collagen; Dobutamine; Dopamine; Dose-Response Relationship, Drug; Epinephrine; Humans; Norepinephrine; Platelet Aggregation; Sympathomimetics; Thromboxane B2; Thromboxanes | 1984 |
Congenital deficiency of thromboxane and prostacyclin.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acids; Aspirin; Blood Coagulation Tests; Blood Platelet Disorders; Cells, Cultured; Chromatography, Thin Layer; Epoprostenol; Hemorrhage; Humans; Male; Oxygenases; Plasma; Platelet Aggregation; Prostaglandins; Thromboxane A2; Thromboxanes | 1980 |
Carrageenan-induced activation of human platelets is independent of phospholipase A2 and of formation of thromboxanes.
Topics: Adenosine Diphosphate; Blood Platelets; Carrageenan; Enzyme Activation; Humans; In Vitro Techniques; Oxygenases; Phospholipases; Phospholipases A; Phospholipases A2; Platelet Aggregation; Thrombin; Thromboxanes | 1980 |
Thromboxane A2 in skin-bleeding-time blood and in clotted venous blood before and after administration of acetylsalicylic acid.
Topics: Adenosine Diphosphate; Adult; Aspirin; Bleeding Time; England; Hemorrhage; Hemostasis; Humans; Male; Platelet Aggregation; Platelet Function Tests; Skin; Sweden; Thromboxane A2; Thromboxane B2; Thromboxanes | 1983 |
Platelet thromboxane synthesis and release reactions in myeloproliferative disorders.
Topics: Adenosine Diphosphate; Adult; Aged; Arachidonic Acid; Arachidonic Acids; beta-Thromboglobulin; Blood Platelets; Calcimycin; Collagen; Epinephrine; Female; Humans; Male; Middle Aged; Myeloproliferative Disorders; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Ristocetin; Serotonin; Thromboxane B2; Thromboxanes | 1982 |
Synergized activation of human platelets by epinephrine and platelet-activating factor-acether is adenosine diphosphate and thromboxane A2-independent.
Topics: Adenosine Diphosphate; Drug Synergism; Epinephrine; Humans; Kinetics; Platelet Activating Factor; Platelet Aggregation; Thromboxane A2; Thromboxanes | 1983 |
Fish oil administration lowers prostacyclin production and the antiaggregatory activity of aortic walls more effectively than platelet aggregation and thromboxane in the rat.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Animals; Aorta; Cell Aggregation; Epoprostenol; Fish Oils; Platelet Aggregation; Prostaglandins; Rats; Thromboxane B2; Thromboxanes | 1983 |
Lanthanum stimulates the accumulation of cyclic AMP and inhibits secretion and thromboxane B2 formation in human platelets.
Topics: Adenosine Diphosphate; Adenylyl Cyclases; Blood Platelets; Calcium; Cyclic AMP; Female; Humans; Lanthanum; Male; Serotonin; Thromboxane B2; Thromboxanes | 1980 |
A role for prostaglandins and thromboxanes in the exposure of platelet fibrinogen receptors.
Topics: Adenosine Diphosphate; Aspirin; Blood Platelets; Epinephrine; Fibrinogen; Humans; Indomethacin; Platelet Aggregation; Platelet Membrane Glycoproteins; Prostaglandins; Prostaglandins A; Prostaglandins H; Receptors, Cell Surface; Thromboxanes | 1981 |
Prostaglandin F2 alpha antagonizes thromboxane A2-induced human platelet aggregation.
Topics: Adenosine Diphosphate; Blood Platelets; Cell Membrane; Cyclic AMP; Dinoprost; Dinoprostone; Drug Antagonism; Epoprostenol; Humans; Kinetics; Platelet Aggregation; Prostaglandins E; Prostaglandins F; Receptors, Prostaglandin; Thromboxane A2; Thromboxanes | 1982 |
The effects of the oral administration of fish oil concentrate on the release and the metabolism of [14C]arachidonic acid and [14C]eicosapentaenoic acid by human platelets.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acids; Blood Platelets; Carbon Radioisotopes; Collagen; Eicosanoic Acids; Eicosapentaenoic Acid; Fatty Acids, Unsaturated; Fish Oils; Humans; Lipids; Male; Platelet Aggregation; Thromboxanes | 1982 |
Formation of thromboxane B2 by platelets and concentrations of thromboxane B2 and 6-keto-prostaglandin F1 alpha in plasma after acute ethanol ingestion.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Blood Platelets; Cyclic AMP; Ethanol; Humans; Kinetics; Male; Thromboxane B2; Thromboxanes | 1983 |
Arachidonic acid-induced platelet aggregation is mediated by a thromboxane A2/prostaglandin H2 receptor interaction.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Arachidonic Acid; Arachidonic Acids; Drug Interactions; Humans; In Vitro Techniques; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Prostanoic Acids; Receptors, Cell Surface; Receptors, Prostaglandin; Receptors, Thromboxane; Thromboxane A2; Thromboxanes | 1984 |
Theophylline inhibits platelet aggregation, prostaglandin and thromboxane production by a mechanism which is independent of cyclic AMP.
Topics: Adenosine Diphosphate; Arachidonic Acids; Blood Platelets; Calcimycin; Cyclic AMP; Dinoprost; Dinoprostone; Humans; In Vitro Techniques; Platelet Aggregation; Prostaglandins; Prostaglandins E; Prostaglandins F; Theophylline; Thromboxanes | 1984 |
Endogenous biosynthesis of prostacyclin and thromboxane and platelet function during chronic administration of aspirin in man.
Topics: Adenosine Diphosphate; Adult; Aspirin; Blood Platelets; Epoprostenol; Humans; Male; Platelet Aggregation; Prostaglandins; Radioimmunoassay; Thromboxanes | 1983 |
The stimulatory effect of prostacyclin (PGI2) on isolated rabbit and rat aorta is probably associated to the generation of a thromboxane A2 (TXA2) "like-material".
Topics: Adenosine Diphosphate; Animals; Aorta, Thoracic; Aspirin; Corticosterone; Epoprostenol; Imidazoles; In Vitro Techniques; Indomethacin; Male; Prostaglandins; Rabbits; Rats; Species Specificity; Thromboxane A2; Thromboxanes; Vasoconstriction | 1983 |
[Introduction to the topic of thromboembolism].
Topics: Adenosine Diphosphate; Blood Coagulation Factors; Blood Platelets; Endothelium; Epoprostenol; Erythrocytes; Fibrinogen; Humans; Thromboembolism; Thromboxanes | 1984 |
Production of prostacyclin, 6-keto-PGF1 alpha and thromboxane B2 by incubated samples of umbilical vessels: a comparison of methods for expressing the results on dry weight, wet weight, protein or DNA bases.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Adult; Epoprostenol; Female; Humans; Organ Specificity; Platelet Aggregation; Pregnancy; Radioimmunoassay; Thromboxane B2; Thromboxanes; Umbilical Arteries; Umbilical Veins | 1984 |
The role of ADP secretion and thromboxane synthesis in factor VIII binding to platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Apyrase; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Collagen; Factor VIII; Humans; Prostaglandin Endoperoxides, Synthetic; Thrombin; Thromboxane A2; Thromboxanes | 1983 |
Effect of ethanol on vascular prostacyclin (prostaglandin I2) synthesis, platelet aggregation, and platelet thromboxane release.
Topics: Adenosine Diphosphate; Animals; Aorta; Arachidonic Acids; Blood Platelets; Collagen; Dose-Response Relationship, Drug; Endothelium; Epinephrine; Epoprostenol; Ethanol; Female; Humans; In Vitro Techniques; Male; Platelet Aggregation; Rats; Thromboxane A2; Thromboxanes; Umbilical Veins | 1983 |
Arachidonic acid induced platelet aggregation and thromboxane formation is inhibited by OKY-1581.
Topics: 6-Ketoprostaglandin F1 alpha; Acrylates; Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Dinoprost; Dinoprostone; Humans; In Vitro Techniques; Male; Methacrylates; Platelet Aggregation; Prostaglandins E; Prostaglandins F; Thromboxane B2; Thromboxanes | 1983 |
Inhibition of prostanoid-mediated platelet aggregation in vivo and in vitro by 3-hydroxymethyl-dibenzo(b,f)thiepin 5,5-dioxide (L-640,035).
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Collagen; Dibenzothiepins; Electric Stimulation; Female; Guinea Pigs; Humans; Male; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Rabbits; Thrombosis; Thromboxane A2; Thromboxane B2; Thromboxanes | 1984 |
A major role of ADP in thromboxane transfer experiments: studies in patients with platelet secretion defects.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cytoplasmic Granules; Humans; In Vitro Techniques; Platelet Aggregation; Serotonin; Thromboxane A2; Thromboxanes | 1984 |
In vitro effect of cimetidine on ADP induced platelet aggregation and thromboxane A2 synthesis in man.
Topics: Adenosine Diphosphate; Centrifugation; Cimetidine; Cold Temperature; Humans; In Vitro Techniques; Platelet Aggregation; Thromboxane A2; Thromboxane B2; Thromboxanes | 1984 |
Inhibition of thromboxane A2 synthesis in human platelets by coagulation factor Xa.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Cattle; Dinoprostone; Factor X; Factor Xa; Humans; Platelet Aggregation; Prostaglandins E; Radioimmunoassay; Thrombin; Thromboxane A2; Thromboxanes | 1983 |
Abnormalities of aggregation, thromboxane A2 synthesis, and 14C serotonin release in platelets of patients with idiopathic scoliosis.
Topics: Adenosine Diphosphate; Adolescent; Adult; Arachidonic Acids; Blood Platelets; Child; Collagen; Epinephrine; Female; Humans; Platelet Aggregation; Scoliosis; Serotonin; Thromboxane A2; Thromboxanes | 1983 |
TXA2-antagonistic properties of agents affecting prostaglandin synthesis or the cyclic nucleotide system in human platelets.
Topics: Adenosine Diphosphate; Blood Platelets; Humans; In Vitro Techniques; Nucleotides, Cyclic; Platelet Aggregation; Prostaglandins; Thromboxane A2; Thromboxanes | 1983 |
Influence of propranolol and 4-hydroxypropranolol on platelet aggregation and thromboxane A2 generation.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acids; Cell Membrane; Dose-Response Relationship, Drug; Epinephrine; Humans; In Vitro Techniques; Platelet Aggregation; Propranolol; Thromboxane A2; Thromboxanes | 1983 |
Effects by nifedipine on thromboxane synthesis in vitro and in vivo.
Topics: Adenosine Diphosphate; Dose-Response Relationship, Drug; Drug Synergism; Epoprostenol; Humans; Nifedipine; Platelet Aggregation; Pyridines; Thromboxanes | 1982 |
Platelet adherence to collagen: role of prostaglandin-thromboxane synthesis.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Calcium; Collagen; Dose-Response Relationship, Drug; Humans; Imidazoles; Indomethacin; Magnesium; Middle Aged; Platelet Adhesiveness; Prostaglandins; Serotonin; Temperature; Thromboxanes | 1981 |
Lithium stimulates thromboxane B2 formation in human platelets.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Dinoprost; Dinoprostone; Humans; Lithium; Platelet Aggregation; Prostaglandins E; Prostaglandins F; Rabbits; Sodium; Thromboxane B2; Thromboxanes | 1981 |
Aggregation and thromboxane B2 formation in platelets and vascular prostacyclin production from genetically obese rats.
Topics: Adenosine Diphosphate; Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Epoprostenol; Obesity; Platelet Aggregation; Prostaglandins; Rats; Rats, Zucker; Thromboxane B2; Thromboxanes | 1981 |
Modulation of Platelet thromboxane A2 and arterial prostacyclin by dietary vitamin E.
Topics: Adenosine Diphosphate; Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Epoprostenol; Male; Prostaglandins; Rats; Rats, Inbred Strains; Thromboxane A2; Thromboxanes; Vitamin E; Vitamin E Deficiency | 1981 |
Thromboxane A2 and the endoperoxides mediate canine platelet activation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Dogs; Dose-Response Relationship, Drug; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandins E; Prostaglandins F; Thromboxane A2; Thromboxane B2; Thromboxanes | 1981 |
Inhibition of platelet thromboxane synthesis by 7-(1-imidazolyl) heptanoic acid: dissociation from inhibition of aggregation.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Drug Synergism; Female; Humans; Imidazoles; Indomethacin; Male; Platelet Aggregation; Thromboxane B2; Thromboxanes; Time Factors | 1981 |
Prostaglandin endoperoxides, thromboxane A2 and adenosine diphosphate in collagen-induced aggregation of rabbit platelets.
Topics: Adenosine Diphosphate; Animals; Collagen; Creatine Kinase; In Vitro Techniques; Indomethacin; Male; Phosphocreatine; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandin-Endoperoxide Synthases; Rabbits; Thromboxane A2; Thromboxanes; Time Factors | 1982 |
Relationship between platelet aggregation, thromboxane synthesis and albumin concentration in nephrotic syndrome.
Topics: Adenosine Diphosphate; Adolescent; Adult; Aged; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cholesterol; Collagen; Female; Humans; Male; Middle Aged; Nephrotic Syndrome; Platelet Aggregation; Serum Albumin; Thromboxane B2; Thromboxanes; Triglycerides | 1982 |
Aggregation and thromboxane formation by platelets and vascular prostacyclin production from BB rats. An animal model for type I diabetes.
Topics: Adenosine Diphosphate; Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Diabetes Mellitus, Experimental; Epoprostenol; Platelet Aggregation; Prostaglandins; Rats; Rats, Inbred Strains; Thromboxane B2; Thromboxanes | 1982 |
Effect of acetylsalicylic acid on platelet aggregation and thromboxane B2 production in flowing aortic blood in the rat studied with a filter loop technique.
Topics: Adenosine Diphosphate; Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Aspirin; Male; Methods; Platelet Aggregation; Rats; Rats, Inbred Strains; Salicylates; Thromboxane B2; Thromboxanes | 1982 |
Are lysophosphatidic acids or phosphatidic acids involved in stimulus activation coupling in platelets?
Topics: Adenosine Diphosphate; Albumins; Blood Platelets; Calcium; Fibrinogen; Humans; Hydrogen-Ion Concentration; Lysophospholipids; Magnesium; Pharmaceutical Vehicles; Phosphatidic Acids; Platelet Aggregation; Thromboxanes | 1982 |
Stimulated platelet aggregation, thromboxane B2 formation and platelet sensitivity to prostacyclin - a critical evaluation.
Topics: Adenosine Diphosphate; Arachidonic Acids; Blood Platelets; Collagen; Epinephrine; Epoprostenol; Evaluation Studies as Topic; Humans; Platelet Aggregation; Platelet Count; Prostaglandins; Thromboxane B2; Thromboxanes; Time Factors | 1981 |
Endotoxin interaction with canine platelets fails to stimulate thromboxane production.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Collagen; Dogs; Endotoxins; Kinetics; Platelet Aggregation; Serratia marcescens; Thromboxanes | 1982 |
Platelet activation by non-coagulant snake venom components.
Topics: Adenosine Diphosphate; Agglutination; Animals; Blood Platelets; Crotalid Venoms; Indomethacin; Platelet Aggregation; Snake Venoms; Species Specificity; Thromboxanes | 1982 |
Thromboxane A2/prostaglandin H2 directly stimulates platelet shape change independent of secreted ADP.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adenosine Triphosphate; Blood Platelets; Humans; In Vitro Techniques; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandins H; Thromboxane A2; Thromboxanes | 1982 |
Generation of thromboxane A2 and aorta-contracting activity from platelets stimulated with modified C-reactive protein.
Topics: Adenosine Diphosphate; Arachidonic Acids; Blood Platelets; C-Reactive Protein; Humans; Indomethacin; Platelet Aggregation; Serotonin; Stimulation, Chemical; Thromboxane A2; Thromboxane B2; Thromboxanes | 1982 |
Effects of ethanol intoxication and hangover on plasma levels of thromboxane B2 and 6-keto-prostaglandin F1 alpha and on thromboxane B2 formation by platelets in man.
Topics: Adenosine Diphosphate; Adult; Alcoholic Intoxication; Blood Platelets; Circadian Rhythm; Ethanol; Humans; Male; Prostaglandins F; Subarachnoid Hemorrhage; Thromboxane B2; Thromboxanes; Time Factors | 1982 |
The relationship between the production of thromboxane B2 and malondialdehyde by human blood platelets.
Topics: Adenosine Diphosphate; Aspirin; Blood Platelets; Humans; In Vitro Techniques; Malonates; Malondialdehyde; Platelet Aggregation; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes | 1980 |
[Action of tioxaprofen on platelet function (author's transl)].
Topics: Adenosine Diphosphate; Alkaline Phosphatase; Anti-Inflammatory Agents; Blood Platelets; Blood Urea Nitrogen; Creatinine; Humans; In Vitro Techniques; Malondialdehyde; Platelet Aggregation; Propionates; Thrombosis; Thromboxanes | 1982 |
Effects of very low versus standard dose acetyl salicylic acid, dipyridamole and sulfinpyrazone on platelet function and thromboxane formation in man.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acids; Aspirin; Blood Platelets; Collagen; Dipyridamole; Dose-Response Relationship, Drug; Female; Humans; Male; Platelet Aggregation; Sulfinpyrazone; Thromboxane B2; Thromboxanes | 1981 |
Effects of heparin on platelet aggregation and release and thromboxane A2 production.
Topics: Adenosine Diphosphate; Adult; Animals; Arachidonic Acids; Blood Platelets; Carbon Radioisotopes; Citrates; Collagen; Epinephrine; Heparin; Humans; Platelet Aggregation; Rabbits; Radioimmunoassay; Serotonin; Thromboxane A2; Thromboxanes; Time Factors | 1981 |
Platelet aggregation independent of ADP release or prostaglandin synthesis in patients with hermansky-Pudlak syndrome.
Topics: Adenosine Diphosphate; Albinism; Arachidonic Acids; Aspirin; Blood Platelets; Epinephrine; Hemorrhagic Disorders; Humans; Platelet Aggregation; Prostaglandins; Thrombin; Thromboxanes | 1981 |
Oral naftidrofuryl prevents platelet hyperreactivity ex vivo and inhibits functional desensitization to prostacyclin in hypercholesterolemic rabbits.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood Platelets; Cholesterol; Collagen; Diet; Epoprostenol; Humans; Hypercholesterolemia; Iloprost; In Vitro Techniques; Male; Nafronyl; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Thromboxanes | 1993 |
Studies on in vitro effect of picotamide on human platelet aggregation in platelet-rich plasma and whole blood.
Topics: Adenosine Diphosphate; Adult; Analysis of Variance; Arachidonic Acid; Collagen; Humans; In Vitro Techniques; Male; Phthalic Acids; Platelet Aggregation; Platelet Aggregation Inhibitors; Thromboxane B2; Thromboxanes | 1995 |
Fibrinogen binding is independent of an increase in intracellular calcium concentration in thrombin degranulated platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Blood Platelets; Calcium; Cell Degranulation; Evaluation Studies as Topic; Fibrinogen; Humans; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Protein Binding; Receptors, Thromboxane; Thromboxane A2; Thromboxanes | 1995 |
ADP-, PAF- and adrenaline-induced platelet aggregation and thromboxane formation are not affected by a thromboxane receptor antagonist at physiological external Ca++ concentrations.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Blood Platelets; Calcium; Citric Acid; Collagen; Epinephrine; Glucose; Hirudins; Humans; Indomethacin; Phenylacetates; Platelet Activating Factor; Platelet Aggregation; Receptors, Thromboxane; Recombinant Proteins; Sulfonamides; Thromboxanes | 1994 |
Inhibition of platelet thromboxane formation and phosphoinositides breakdown by diisoeugenol.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Blood Platelets; Collagen; Cyclic AMP; Eugenol; Humans; Membrane Lipids; Phosphatidylinositols; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Thrombin; Thromboxanes | 1994 |
Effect of naftidrofuryl on platelet-induced vasospasm in vitro. Role of antiserotonergic actions.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Blood Platelets; Cattle; Coronary Vessels; Dinoprost; Humans; In Vitro Techniques; Muscle Contraction; Muscle Tonus; Muscle, Smooth, Vascular; Nafronyl; Potassium Chloride; Prostaglandin Endoperoxides, Synthetic; Serotonin Antagonists; Thromboxanes; Vasoconstrictor Agents | 1993 |
Platelets, alcohol consumption, and onset of brain infarction.
Topics: Adenosine Diphosphate; Adolescent; Adult; Alcohol Drinking; Alcoholism; Brain Ischemia; Female; Humans; Hypertension; In Vitro Techniques; Infant, Newborn; Male; Middle Aged; Platelet Aggregation; Platelet Count; Thrombocytopenia; Thrombocytosis; Thromboxanes | 1996 |
Acute methionine load-induced hyperhomocysteinemia enhances platelet aggregation, thromboxane biosynthesis, and macrophage-derived tissue factor activity in rats.
Topics: Adenosine Diphosphate; Amino Acids; Analysis of Variance; Animals; Blood Platelets; Diet; Folic Acid Deficiency; Glutathione; Homocysteine; Lipid Peroxidation; Macrophages, Peritoneal; Male; Malondialdehyde; Methionine; Platelet Aggregation; Rats; Rats, Sprague-Dawley; Regression Analysis; Thiobarbituric Acid Reactive Substances; Thrombin; Thromboplastin; Thromboxanes | 1997 |
Habitual smoking causes an abnormality in platelet thromboxane A2 metabolism and results in an altered susceptibility to aspirin effects.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adult; Aspirin; Blood Platelets; Collagen; Epoprostenol; Erythrocytes; Humans; Male; Platelet Aggregation; Smoking; Thromboxane A2; Thromboxanes | 2000 |
Functional expression of CCR1, CCR3, CCR4, and CXCR4 chemokine receptors on human platelets.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adult; Blood Platelets; Blotting, Western; Calcium Signaling; Chemokines; Chondroitin ABC Lyase; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Precursors; Feedback; Flow Cytometry; Gene Expression Regulation; Heparin; Heparin Lyase; Heparin, Low-Molecular-Weight; Humans; Intracellular Signaling Peptides and Proteins; Isoenzymes; Peptide Fragments; Phospholipase C gamma; Phosphorylation; Platelet Aggregation; Polymerase Chain Reaction; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Purinergic P2 Receptor Antagonists; Receptors, CCR1; Receptors, CCR3; Receptors, CCR4; Receptors, Chemokine; Receptors, CXCR4; Receptors, IgG; Receptors, Purinergic P2; RNA, Messenger; Syk Kinase; Thromboxanes; Transfection; Type C Phospholipases | 2000 |
Signalling components underlying platelet aggregation to a Ca2+ ionophore and a phorbol ester.
Topics: Adenosine Diphosphate; Androstadienes; Calcimycin; Calcium Signaling; Chromones; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Humans; Indoles; Ionophores; Morpholines; Phosphatidylinositol 3-Kinases; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Serotonin; Signal Transduction; Tetradecanoylphorbol Acetate; Thromboxanes; Type C Phospholipases; Wortmannin | 2001 |
Thrombopoietin complements G(i)- but not G(q)-dependent pathways for integrin {alpha}(IIb){beta}(3) activation and platelet aggregation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Androstadienes; Antibodies, Monoclonal; Blood Platelets; Blood Proteins; Calcium; Chromones; Cyclooxygenase Inhibitors; Cytosol; Enzyme Activation; Enzyme Inhibitors; Fibrinogen; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; Humans; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoproteins; Platelet Activation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Proto-Oncogene Proteins; rap GTP-Binding Proteins; Receptors, Cytokine; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Thrombopoietin; Thrombopoietin; Thromboxane A2; Thromboxanes; Time Factors; Type C Phospholipases; Wortmannin | 2005 |
Usefulness of whole blood aggregometry and its comparison with thromboxane generation assay in monitoring acetylsalicylic acid effectiveness--a multiparametric study in rats.
Topics: Adenosine Diphosphate; Animals; Aspirin; Biomarkers; Blood Platelets; Cell Aggregation; Collagen; Male; Nephelometry and Turbidimetry; Platelet Aggregation; Rats; Rats, Wistar; Thromboxanes; Time Factors | 2006 |
Reciprocal regulation of platelet responses to P2Y and thromboxane receptor activation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Blood Platelets; Calcium; Cyclic AMP; Cytosol; Humans; Platelet Activation; Platelet Aggregation; Protein Kinase C; Receptors, Purinergic P2; Receptors, Thromboxane; Serotonin; Signal Transduction; Thromboxanes | 2008 |
Mechanism of activation and functional role of protein kinase Ceta in human platelets.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Animals; Blood Platelets; Enzyme Activation; GTP-Binding Protein alpha Subunits, Gq-G11; Humans; Integrin alpha2; Mice; Mice, Knockout; Peptides, Cyclic; Phosphorylation; Platelet Aggregation; Protein Kinase C; Protein Phosphatase 1; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Thromboxanes | 2009 |
Spice active principles as the inhibitors of human platelet aggregation and thromboxane biosynthesis.
Topics: Acrolein; Adenosine Diphosphate; Alkaloids; Allyl Compounds; Arachidonic Acid; Benzodioxoles; Calcimycin; Capsaicin; Collagen Type III; Curcumin; Eugenol; Humans; Malondialdehyde; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Polyunsaturated Alkamides; Quercetin; Spices; Sulfides; Thromboxanes | 2009 |
Salvianolic acid A inhibits platelet activation and arterial thrombosis via inhibition of phosphoinositide 3-kinase.
Topics: Adenosine Diphosphate; Adult; Animals; Arteries; Caffeic Acids; Collagen; Dose-Response Relationship, Drug; Female; Flow Cytometry; Humans; Lactates; Male; Mice; Phosphoinositide-3 Kinase Inhibitors; Platelet Activation; Platelet Aggregation; Signal Transduction; Thrombin; Thrombosis; Thromboxanes | 2010 |
[The role of prostaglandins in platelet aggregation in metabolic syndrome].
Topics: Adenosine Diphosphate; Arachidonic Acid; Blood Platelets; Collagen; Cyclic AMP; Epinephrine; Epoprostenol; Hemostasis; Humans; In Vitro Techniques; Metabolic Syndrome; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandins; Thromboxanes; von Willebrand Factor | 2010 |
Exercise training alters the balance between vasoactive compounds in skeletal muscle of individuals with essential hypertension.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adult; Analysis of Variance; Biomarkers; Blood Pressure Determination; Blotting, Western; Case-Control Studies; Epoprostenol; Exercise; Female; Humans; Hypertension; Male; Middle Aged; Muscle, Skeletal; Physical Education and Training; Reference Values; Thromboxanes | 2011 |
Protein kinase C isoform ε negatively regulates ADP-induced calcium mobilization and thromboxane generation in platelets.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Calcium; Disease Models, Animal; Humans; Intracellular Fluid; Mice; Platelet Aggregation; Platelet Count; Protein Kinase C-epsilon; Signal Transduction; Thrombosis; Thromboxanes | 2012 |
Rutin present in Alibertia edulis extract acts on human platelet aggregation through inhibition of cyclooxygenase/thromboxane.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Arachidonic Acid; Calcium; Collagen; Cyclooxygenase Inhibitors; Gene Expression Regulation; Humans; Plant Extracts; Plant Leaves; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Rubiaceae; Thromboxanes; Zebrafish | 2021 |
Specific inhibition of the transporter MRP4/ABCC4 affects multiple signaling pathways and thrombus formation in human platelets.
Topics: Adenosine Diphosphate; ATP-Binding Cassette Transporters; Blood Platelets; Calcium; Fluorescein-5-isothiocyanate; Humans; Integrins; Multidrug Resistance-Associated Proteins; Nucleotides, Cyclic; Signal Transduction; Thrombosis; Thromboxanes | 2022 |
Effectiveness of aspirin vs. clopidogrel in dogs with immune mediated haemolytic anaemia evaluated by serial thromboelastography and platelet mapping.
Topics: Adenosine Diphosphate; Anemia, Hemolytic, Autoimmune; Animals; Aspirin; Blood Platelets; Clopidogrel; Dog Diseases; Dogs; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Thrombelastography; Thromboxanes | 2022 |
High-Intensity Exercise Training Improves Basal Platelet Prostacyclin Sensitivity and Potentiates the Response to Dual Anti-Platelet Therapy in Postmenopausal Women.
Topics: Adenosine; Adenosine Diphosphate; Aspirin; Cyclooxygenase 1; Diphosphates; Dual Anti-Platelet Therapy; Epoprostenol; Estrogens; Exercise; Female; Humans; Nitric Oxide; Peptides; Platelet Aggregation Inhibitors; Postmenopause; Receptors, Epoprostenol; Receptors, Thromboxane; Thrombin; Thrombosis; Thromboxanes | 2022 |