adenosine diphosphate has been researched along with suramin in 100 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (2.00) | 18.7374 |
1990's | 42 (42.00) | 18.2507 |
2000's | 42 (42.00) | 29.6817 |
2010's | 13 (13.00) | 24.3611 |
2020's | 1 (1.00) | 2.80 |
Authors | Studies |
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Harden, TK; Schachter, JB | 1 |
Jacobson, KA; Jarvis, MF; Williams, M | 1 |
Boyer, JL; Corbitt, J; Harden, TK; Jacobson, KA; Ji, XD; Kim, HS; Lacy, J; Ravi, G; Waldo, GL | 1 |
Boeynaems, JM; Communi, D; Gonzalez, NS; Labouret, C; Le Poul, E; Marteau, F; Savi, P | 1 |
Späth, L; Starke, K; von Kügelgen, I | 1 |
Hall, DA; Hourani, SM; Nieman, CJ | 1 |
Amerini, S; Ledda, F; Mantelli, L; Rubino, A | 1 |
Jones, CE; Reid, DM; Shulman, NR; Vostal, JG | 1 |
Blakeley, AG; Dunn, PM | 1 |
Bäumert, HG; Breddin, HK; Lambrecht, G; Mutschler, E; Radziwon, P; Windscheif, U | 1 |
Akaike, N; Ebihara, S; Uneyama, C; Uneyama, H | 1 |
Giachetti, A; Maggi, CA; Santicioli, P; Zagorodnyuk, V | 1 |
Fu, WM; Liou, JC | 1 |
Hashimoto, M; Kokubun, S | 1 |
Starke, K; Stoffel, D; von Kügelgen, I | 1 |
Balcar, VJ; Bennett, MR; Killinger, S; Li, Y | 1 |
Abe, Y; Akaike, N; Furukawa, K; Itoyama, Y; Sorimachi, M | 1 |
Chen, ZP; Levy, A; Lightman, SL | 1 |
Caparrotta, L; Chinellato, A; Fassina, G; Froldi, G; Pandolfo, L; Ragazzi, E | 1 |
Hall, DA; Hourani, SM | 1 |
Arnold, HH; Salminen, A | 1 |
Bidet, M; Cejka, JC; Poujeol, P; Tauc, M | 1 |
Culic, O; Lemmens, R; Teuchy, H; Vanduffel, L | 1 |
Barnard, EA; Burnstock, G; King, BF; Simon, J; Webb, TE | 1 |
Burnstock, G; Ralevic, V | 1 |
Nakamura, S; Ohshita, T; Sawamoto, N; Yamashita, H; Zhang, YX | 1 |
Li, CG; Najbar, AT; Rand, MJ | 1 |
Bültmann, R; Kurz, G; Nickel, P; Pause, B; Starke, K; Wittenburg, H | 1 |
Cazenave, JP; Gachet, C; Hechler, B; Léon, C; Leray, C; Vial, C | 1 |
Boeynaems, JM; Communi, D; Robaye, B | 2 |
Furukawa, M; Ikeda, K; Suzuki, H; Takasaka, T | 1 |
Maggi, CA; Zagorodnyuk, V | 1 |
Korngreen, A; Ma, W; Priel, Z; Silberberg, SD | 1 |
Dunne, MJ; James, RF; London, NJ; Squires, PE | 1 |
Connolly, GP; Demaine, C; Duley, JA | 1 |
Bernard, C; Butlen, D; Ferrary, E | 1 |
Ito, S; Nakazato, Y; Ohta, T; Otsuguro, K | 1 |
Cha, SH; Endou, H; Sekine, T | 1 |
Chen, SA; Jan, CR; Li, HF; Wu, SN | 1 |
Grantyn, R; Jüttner, R; Taschenberger, H | 1 |
Habuchi, Y; Morikawa, J; Nishio, M; Tanaka, H; Yamamoto, T | 1 |
Henning, L; Jankowski, J; Junker, R; Schlüter, H; Tente, IM; Tepel, M; van der Giet, M; Zidek, W | 1 |
Hourani, SM; Park, HS | 1 |
Katsuragi, T; Sato, C; Tsujioka, Y | 1 |
Barthó, L; Heinemann, A; Holzer, P; Shahbazian, A | 1 |
Figarella, C; Kammouni, W; Merten, MD; Picher, M; Saleh, A | 1 |
Dixon, CJ; Green, AK; Webb, TE; Woods, NM | 1 |
Nikbakht, MR; Stone, TW | 1 |
Carolan, BM; Harden, TK; Keef, KD; Mutafova-Yambolieva, VN | 1 |
Boeynaems, JM; Castro, E; Communi, D; Delicado, EG; Jiménez, AI; Miras-Portugal, MT | 1 |
Saino, T; Shinohe, Y | 1 |
Bültmann, R; Starke, K | 1 |
Banes, AJ; Elfervig, MK; Graff, RD; Kelley, SS; Lee, GM; Sood, A | 1 |
Bernardes, CF; Castilho, RF; Fagian, MM; Meyer-Fernandes, JR; Vercesi, AE | 1 |
Chiba, T; Lee, JH; Marcus, DC | 1 |
Imamura, H; Kido, M; Lu, K; Ninomiya, H; Otani, H; Uchiyama, T | 1 |
Bell, PD; Johansson, A; Kovacs, G; Liu, R; Persson, AE; Peti-Peterdi, J | 1 |
Katayama, T; Kawaguchi, N; Minami, M; Nakagawa, T; Nakamura, J; Ohtani, Y; Satoh, M; Yamakuni, H | 1 |
Mihaylova-Todorova, ST; Todorov, LD; Westfall, DP | 1 |
Chambers, JK; Emson, PC; Moore, DJ; Murdock, PR | 1 |
Hoyle, CH; Martín, S; Peláez, T; Peral, A; Pintor, J | 1 |
Alessandro, M; Mulè, F; Serio, R; Tamburello, MP; Zizzo, MG | 1 |
Laubinger, W; Reiser, G; Wang, H; Welte, T | 1 |
Allen, DG; Barden, JA; Huang, W; Jiang, L; Ju, YK | 1 |
Delbro, DS; Nordgren, S; Nylund, G | 1 |
Buljubasich, R; Ventura, S | 1 |
Fachinetto, R; Nogueira, CW; Rocha, JB; Savegnago, L | 1 |
Almeida, T; Cunha, RA; Oliveira, CR; Richardson, PJ; Rodrigues, RJ | 1 |
Hildebrandt, C; Horner, S; Kassack, MU; Lambrecht, G; Mahaut-Smith, MP; Menke, K; Nickel, P; Ullmann, H | 1 |
Burnstock, G; Cowen, T; Knight, GE; Wallace, A | 1 |
Barreto-Chaves, ML; Fürstenau, CR; Sarkis, JJ; Trentin, Dda S | 1 |
Bielarczyk, H; Jankowska-Kulawy, A; Klimaszewska, J; Michno, A; Pawełczyk, T; Szutowicz, A | 1 |
Housley, GD; Soeller, C; Thorne, PR; Vlajkovic, SM; Wang, CJ; Zimmermann, H | 1 |
Singleton, SF; Wigle, TJ | 1 |
Bowser, DN; Khakh, BS | 1 |
Kauffenstein, G; Kukulski, F; Lavoie, EG; Lecka, J; Legendre, C; Lévesque, SA; Munkonda, MN; Pelletier, J; Sévigny, J | 1 |
Almeida, ME; Libermann, TA; Rücker, B; Sarkis, JJ; Wink, MR; Zerbini, LF | 1 |
Avelino-Cruz, JE; Berra-Romani, R; Moccia, F; Oldani, A; Raqeeb, A; Speroni, F; Taglietti, V; Tanzi, F | 1 |
Günthner, T; Jalkanen, S; Jankowski, J; Jankowski, V; Yegutkin, GG; Zidek, W | 1 |
Cofan, M; Crumm, S; Hoek, JB; Juskeviciute, E | 1 |
Chow, JY; Dong, H; Dong, X; Insel, PA; Kim, HD; Ko, KH; Lee, J; Smoll, EJ | 1 |
Barrabin, H; Esteves, FF; Meyer-Fernandes, JR; Moreira, OC; Rios, PF | 1 |
Acheson, A; Eames, T; Mundey, M; Nisar, P; Rayment, S; Scholefield, J; Wilson, VG | 1 |
Grace, AA; Gurung, IS; Huang, CL; Kalin, A | 1 |
Baqi, Y; Glänzel, M; Hoffmann, K; Morena, MS; Müller, CE; von Kügelgen, I | 1 |
Andersson, M; Aronsson, P; Ericsson, T; Giglio, D | 1 |
Hempel, D; Kurup, IV; Masuda, I; Rosenthal, AK; Ryan, LM | 1 |
Kanjanamekanant, K; Luckprom, P; Pavasant, P | 1 |
Auld, DS; Blackburn, EA; Boxer, MB; Fothergill-Gilmore, LA; McNae, IW; Michels, PA; Morgan, HP; Nowicki, MW; Shen, M; Veith, H; Walkinshaw, MD; Walsh, MJ; Wear, MA | 1 |
Caruso-Neves, C; Costa-Alves, MS; Meyer-Fernandes, JR; Pinheiro, AA; Ribeiro, MC; Wengert, M; Zancan, P | 1 |
Bravo, CE; Capettini, LS; Carmo, AO; Chávez-Olórtegui, C; Gomes, MT; Horta, CC; Kalapothakis, E; Lemos, VS; Oliveira-Mendes, BB; Rezende, BA; Silva, JF | 1 |
Arakawa, T; Ito, M; Mizoguchi, I; Okayama, M; Shitara, A; Takuma, T | 1 |
Bao, Y; Chen, Y; Inoue, Y; Junger, WG; Li, X; Sumi, Y; Tanaka, H; Woehrle, T; Yao, Y | 1 |
Drumm, BT; Durnin, L; Hwang, SJ; Kurahashi, M; Mutafova-Yambolieva, VN; Sanders, KM; Sasse, KC; Ward, SM | 1 |
Gan, X; Hu, WP; Qiu, CY; Ren, C; Wu, J | 1 |
Adefegha, SA; Cabral, FL; Doleski, PH; Leal, DB | 1 |
Guo, B; Hu, F; Jiang, P; Lee, I; Li, Z; Pan, L; Wei, W; Xing, F; Xu, J; Yang, J; Zhang, X | 1 |
Caringal, H; Gongwer, M; Heer, C; Jacoby, J; Kaufman, R; Kreitzer, MA; Malchow, RP; Shepherd, L; Swygart, D; Tchernookova, BK; Young, M | 1 |
Hamaguchi, S; Kariya, M; Namekata, I; Ozaki, AF; Tanaka, H | 1 |
1 review(s) available for adenosine diphosphate and suramin
Article | Year |
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Purine and pyrimidine (P2) receptors as drug targets.
Topics: Adenosine Triphosphate; Animals; Drug Design; Humans; Ligands; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyrimidines; Receptors, Purinergic P2; Uridine Triphosphate | 2002 |
99 other study(ies) available for adenosine diphosphate and suramin
Article | Year |
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An examination of deoxyadenosine 5'(alpha-thio)triphosphate as a ligand to define P2Y receptors and its selectivity as a low potency partial agonist of the P2Y1 receptor.
Topics: Adenosine Triphosphate; Dose-Response Relationship, Drug; Humans; Radioligand Assay; Receptors, Purinergic P2; Receptors, Purinergic P2Y1 | 1997 |
Quantitation of the P2Y(1) receptor with a high affinity radiolabeled antagonist.
Topics: Adenosine Diphosphate; Animals; Cells, Cultured; Female; Humans; Insecta; Purinergic P2 Receptor Antagonists; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Tritium | 2002 |
Pharmacological characterization of the human P2Y13 receptor.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cell Membrane; CHO Cells; Cricetinae; Cyclic AMP; Female; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Inositol Phosphates; Kinetics; Receptors, Purinergic P2; Thionucleotides | 2003 |
Stable adenine nucleotides inhibit [3H]-noradrenaline release in rabbit brain cortex slices by direct action at presynaptic adenosine A1-receptors.
Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cerebral Cortex; Drug Interactions; Drug Stability; Electric Stimulation; Female; Male; Nerve Endings; Norepinephrine; Purinergic Antagonists; Rabbits; Receptors, Purinergic; Suramin; Synapses; Theophylline; Tritium; Xanthines | 1992 |
Effects of the P2-purinoceptor antagonist, suramin, on human platelet aggregation induced by adenosine 5'-diphosphate.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Blood Platelets; Humans; In Vitro Techniques; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Receptors, Purinergic; Serotonin; Suramin | 1992 |
ATP modulates the efferent function of capsaicin-sensitive neurones in guinea-pig isolated atria.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Guinea Pigs; Heart Atria; In Vitro Techniques; Male; Neurons, Efferent; Receptors, Purinergic; Suramin; Theophylline | 1992 |
Anion channel blockers cause apparent inhibition of exocytosis by reacting with agonist or secretory product, not with cell.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Diphosphate; Anions; Blood Platelets; Calcimycin; Cell Membrane; Collagen; Erythrocytes; Exocytosis; Humans; Ion Channels; Kinetics; Malondialdehyde; Serotonin; Stilbenes; Suramin; Thrombin | 1989 |
Suramin: a reversible P2-purinoceptor antagonist in the mouse vas deferens.
Topics: Adenosine Diphosphate; Animals; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Muscle Contraction; Muscle, Smooth; Receptors, Purinergic; Suramin | 1988 |
Two different inhibitory effects of pyridoxalphosphate-6-azophenyl-2',4'-disulfonic acid on adenosine diphosphate-induced human platelet aggregation.
Topics: Adenosine Diphosphate; Humans; In Vitro Techniques; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Suramin | 1995 |
Suramin and reactive blue 2 are antagonists for a newly identified purinoceptor on rat megakaryocyte.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Electrophysiology; Female; Inositol 1,4,5-Trisphosphate; Ion Channels; Male; Megakaryocytes; Potassium; Protein Synthesis Inhibitors; Purinergic Antagonists; Rats; Rats, Wistar; Suramin; Thrombin; Triazines | 1994 |
Evidence that tachykinin NK1 and NK2 receptors mediate non-adrenergic non-cholinergic excitation and contraction in the circular muscle of guinea-pig duodenum.
Topics: Action Potentials; Adenosine Diphosphate; Animals; Apamin; Arginine; Atropine; Dose-Response Relationship, Drug; Duodenum; Electric Stimulation; Guanethidine; Guinea Pigs; Indomethacin; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin-1 Receptor Antagonists; Neuromuscular Junction; Nifedipine; Nitroarginine; Oligopeptides; Peptide Fragments; Peptides, Cyclic; Physalaemin; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P; Suramin; Thionucleotides | 1995 |
Additive effect of ADP and CGRP in modulation of the acetylcholine receptor channel in Xenopus embryonic myocytes.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcitonin Gene-Related Peptide; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Dibutyryl Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Heart; Myocardium; Patch-Clamp Techniques; Protein Kinase C; Receptors, Cholinergic; Receptors, Purinergic; Suramin; Tetradecanoylphorbol Acetate; Xenopus laevis | 1995 |
Contribution of P2-purinoceptors to neurogenic contraction of rat urinary bladder smooth muscle.
Topics: Acetylcholine; Adenosine Diphosphate; Adenosine Triphosphate; Analysis of Variance; Animals; Atropine; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Isotonic Contraction; Male; Muscle, Smooth; Parasympatholytics; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Receptors, Purinergic P2; Suramin; Thionucleotides; Triazines; Urinary Bladder | 1995 |
P2-purinoceptor-mediated inhibition of noradrenaline release in rat atria.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antihypertensive Agents; Atropine; Desipramine; Dose-Response Relationship, Drug; Electric Stimulation; Heart Atria; Indomethacin; Male; Norepinephrine; Phenethylamines; Protein Synthesis Inhibitors; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Suramin; Triazines; Xanthines; Yohimbine | 1995 |
Autoradiography of P2x ATP receptors in the rat brain.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Autoradiography; Binding, Competitive; Brain; Brain Stem; Cerebellum; Cerebral Cortex; Dilazep; Female; Hippocampus; Ligands; Male; Ouabain; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Structure-Activity Relationship; Suramin; Thalamus; Thionucleotides | 1995 |
ATP responses in the embryo chick ciliary ganglion cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Chick Embryo; Dose-Response Relationship, Drug; Electrophysiology; Ganglia, Parasympathetic; Patch-Clamp Techniques; Suramin | 1995 |
Activation of specific ATP receptors induces a rapid increase in intracellular calcium ions in rat hypothalamic neurons.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Cytosol; Fetus; Guanosine Triphosphate; Hypothalamus; Kinetics; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Neurotransmitter; Receptors, Purinergic P2; Structure-Activity Relationship; Suramin | 1994 |
Purine- and nucleotide-mediated relaxation of rabbit thoracic aorta: common and different sites of action.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; In Vitro Techniques; Inosine; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nucleotides; Purines; Rabbits; Suramin; Uridine Triphosphate; Vasodilator Agents | 1994 |
Effects of suramin on increases in cytosolic calcium and on inhibition of adenylate cyclase induced by adenosine 5'-diphosphate in human platelets.
Topics: Adenosine Diphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alprostadil; Blood Platelets; Calcium; Cyclic AMP; Cytosol; Epinephrine; Humans; In Vitro Techniques; Suramin | 1994 |
Differentiation of BA-HAN-1C rhabdomyosarcoma cells is controlled by a pertussis toxin sensitive signaling pathway.
Topics: Adenosine Diphosphate; Animals; Cell Differentiation; Cell Transformation, Neoplastic; Cyclic AMP; Fibroblast Growth Factor 2; Gene Expression Regulation; GTP Phosphohydrolases; GTP-Binding Proteins; Muscles; Myogenin; Pertussis Toxin; Phenotype; Rats; Rhabdomyosarcoma; Ribose; Signal Transduction; Suramin; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1993 |
Nucleotides mobilize intracellular calcium stores of renal proximal cells in primary culture: existence of a suramin-sensitive mechanism.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Bordetella pertussis; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Fura-2; Kidney Tubules, Proximal; Male; Nucleotides; Rabbits; Suramin | 1993 |
Regulation of proliferation of LLC-MK2 cells by nucleosides and nucleotides: the role of ecto-enzymes.
Topics: 5'-Nucleotidase; Acid Anhydride Hydrolases; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Alkaline Phosphatase; Animals; Cell Division; Cell Line; Cell Line, Transformed; Dinucleoside Phosphates; Dipyridamole; Enzyme Inhibitors; HeLa Cells; Humans; Levamisole; Nucleoside-Triphosphatase; Nucleosides; Nucleotides; Suramin; Thymidine; Triazines | 1996 |
Characterisation of a recombinant P2Y purinoceptor.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Animals; Brain; Cell Line; Electrophysiology; Inositol Phosphates; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Recombinant Proteins; Suramin; Thionucleotides; Triazines; Uridine Triphosphate; Xenopus | 1995 |
Relative contribution of P2U- and P2Y-purinoceptors to endothelium-dependent vasodilatation in the golden hamster isolated mesenteric arterial bed.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cricetinae; Endothelium, Vascular; Male; Mesenteric Arteries; Methoxamine; Muscle Contraction; Muscle Tonus; Muscle, Smooth; Rats; Receptors, Purinergic P2; Suramin; Uridine Triphosphate; Vasoconstrictor Agents; Vasodilation | 1996 |
ATP induces release of newly synthesized dopamine in the rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; alpha-Methyltyrosine; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Corpus Striatum; Dopamine; Homovanillic Acid; Kinetics; Male; Methyltyrosines; Microdialysis; Neurons; omega-Conotoxin GVIA; Peptides; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Reserpine; Suramin; Tetrodotoxin; Xanthines | 1996 |
Evidence for two distinct P2-purinoceptors subserving contraction of the rat anococcygeus smooth muscle.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Male; Muscle Contraction; Muscle, Smooth; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Suramin | 1996 |
P2-purinoceptor antagonists: III. Blockade of P2-purinoceptor subtypes and ecto-nucleotidases by compounds related to suramin.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Colon; Guinea Pigs; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Purinergic P2 Receptor Antagonists; Rats; Structure-Activity Relationship; Suramin; Thionucleotides; Vas Deferens | 1996 |
The P2Y1 receptor is an ADP receptor antagonized by ATP and expressed in platelets and megakaryoblastic cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Binding, Competitive; Blood Platelets; Calcium; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Humans; Jurkat Cells; Megakaryocytes; Membrane Proteins; Polymerase Chain Reaction; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Suramin | 1997 |
Slow desensitization of the human P2Y6 receptor.
Topics: Adenosine Diphosphate; GTP-Binding Proteins; Humans; Inositol 1,4,5-Trisphosphate; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Suramin; Triazines; Tumor Cells, Cultured; Uridine Diphosphate | 1997 |
P2 purinoceptor of the globular substance in the otoconial membrane of the guinea pig inner ear.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Enzyme Inhibitors; Estrenes; Guinea Pigs; Kinetics; Otolithic Membrane; PC12 Cells; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyrrolidinones; Rats; Receptors, Purinergic P2; Saccule and Utricle; Suramin; Triazines; Type C Phospholipases; Uridine Triphosphate | 1997 |
Pharmacological evidence for the existence of multiple P2 receptors in the circular muscle of guinea-pig colon.
Topics: Adenosine Diphosphate; Animals; Apamin; Autonomic Nervous System; Colon; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Indoles; Male; Muscle Contraction; Muscle, Smooth; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Agonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Suramin; Thionucleotides; Vasodilator Agents | 1998 |
Extracellular ATP directly gates a cation-selective channel in rabbit airway ciliated epithelial cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antineoplastic Agents; Barium Compounds; Cations, Divalent; Cesium; Chlorides; Cilia; Electric Conductivity; Electric Stimulation; Epithelial Cells; Extracellular Space; GTP-Binding Proteins; Ion Channel Gating; Ion Channels; Male; Mucous Membrane; Patch-Clamp Techniques; Rabbits; Receptors, Purinergic P2; Suramin; Tetraethylammonium; Trachea; Uridine Triphosphate | 1998 |
Characterization of purinergic receptor-evoked increases in intracellular Ca2+ transients in isolated human and rodent insulin-secreting cells. Purinergic receptor signalling and [Ca2+]i in human beta-cells.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cadaver; Calcium; Cells, Cultured; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Models, Biological; Receptors, Purinergic; Rodentia; Signal Transduction; Suramin; Tissue Donors; Uridine Triphosphate | 1997 |
Ecto-nucleotidases in isolated intact rat vagi, nodose ganglia, and superior cervical ganglia.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Enzyme Inhibitors; Evoked Potentials; In Vitro Techniques; Male; Nodose Ganglion; Rats; Rats, Wistar; Superior Cervical Ganglion; Suramin; Vagus Nerve | 1998 |
Pharmacological characterization of ATP receptors in ampulla from frog semicircular canal.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Binding, Competitive; Female; Kinetics; Male; Radioligand Assay; Rana ridibunda; Receptors, Purinergic P2; Semicircular Canals; Suramin; Thionucleotides | 1998 |
Two types of relaxation-mediating P2 receptors in rat gastric circular muscle.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antineoplastic Agents; Apamin; Dose-Response Relationship, Drug; Gastric Mucosa; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Stomach; Suramin; Thionucleotides | 1998 |
P2 purinoceptor localization along rat nephron and evidence suggesting existence of subtypes P2Y1 and P2Y2.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Calcium Channel Blockers; Gallic Acid; Kidney Glomerulus; Kidney Tubules, Collecting; Male; Nephrons; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Suramin; Thionucleotides; Uridine Triphosphate | 1998 |
Stimulation of large-conductance Ca2+-activated K+ channels by Evans blue in cultured endothelial cells of human umbilical veins.
Topics: Adenosine Diphosphate; Capillary Permeability; Cells, Cultured; Endothelium, Vascular; Evans Blue; Humans; Kinetics; Large-Conductance Calcium-Activated Potassium Channels; Membrane Potentials; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Calcium-Activated; Suramin; Umbilical Veins | 1999 |
Ca2+-permeable P2X receptor channels in cultured rat retinal ganglion cells.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Kinetics; Membrane Potentials; Patch-Clamp Techniques; Rats; Receptors, Purinergic P2; Regression Analysis; Retinal Ganglion Cells; Suramin | 1999 |
P2 purinoceptors contribute to ATP-induced inhibition of L-type Ca2+ current in rabbit atrial myocytes.
Topics: 1-Methyl-3-isobutylxanthine; 5'-Nucleotidase; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Calcium-Transporting ATPases; Colforsin; Cyclic AMP; Enzyme Inhibitors; Isoproterenol; Myocardium; Patch-Clamp Techniques; Pertussis Toxin; Potassium Channels; Potassium Channels, Voltage-Gated; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rabbits; Receptors, Purinergic P2; Shal Potassium Channels; Suramin; Virulence Factors, Bordetella; Xanthines | 1999 |
Identification and characterization of P(1), P(7)-Di(adenosine-5')-heptaphosphate from human platelets.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Dinucleoside Phosphates; Humans; Platelet Aggregation; Rats; Suramin; Thrombin; Vasoconstriction; Vasoconstrictor Agents | 1999 |
Differential effects of adenine nucleotide analogues on shape change and aggregation induced by adnosine 5-diphosphate (ADP) in human platelets.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Blood Platelets; Cell Size; Dose-Response Relationship, Drug; Humans; Platelet Aggregation; Suramin; Thionucleotides; Trypanocidal Agents; Uridine Triphosphate | 1999 |
Cross desensitizations on contractions by P2-agonists of guinea pig ileum.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Receptors, Purinergic P2; Suramin; Tetrodotoxin | 1999 |
Different receptors mediating the inhibitory action of exogenous ATP and endogenously released purines on guinea-pig intestinal peristalsis.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apamin; Female; Guinea Pigs; Ileum; In Vitro Techniques; Intestines; Male; Peristalsis; Purines; Pyridoxal Phosphate; Receptors, Purinergic; Receptors, Purinergic P2; Suramin; Thionucleotides | 1999 |
Pharmacological characterization of the human P2Y11 receptor.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; CHO Cells; Cricetinae; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Inositol 1,4,5-Trisphosphate; Phosphoadenosine Phosphosulfate; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Recombinant Fusion Proteins; Suramin; Theophylline; Thionucleotides; Time Factors; Triazines; Tumor Cells, Cultured | 1999 |
Characterization of a diadenosine tetraphosphate-receptor distinct from the ATP-purinoceptor in human tracheal gland cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Binding, Competitive; Calcium; Cells, Cultured; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Humans; Hydrolysis; Proteinase Inhibitory Proteins, Secretory; Proteins; Receptors, Purinergic P2; Secretory Leukocyte Peptidase Inhibitor; Suramin; Thionucleotides; Trachea | 1999 |
Evidence that rat hepatocytes co-express functional P2Y1 and P2Y2 receptors.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; DNA, Complementary; Liver; Male; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Suramin; Uridine Diphosphate; Uridine Triphosphate | 2000 |
Complex hippocampal responses to ATP: fade due to nucleotidase inhibition and P2-receptor-mediated adenosine release.
Topics: 5'-Nucleotidase; Action Potentials; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Enzyme Inhibitors; Hippocampus; Male; Nerve Tissue Proteins; Rats; Rats, Wistar; Receptors, Purinergic P2; Suramin; Theophylline | 2000 |
Multiple P2Y receptors mediate contraction in guinea pig mesenteric vein.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Guinea Pigs; In Vitro Techniques; Male; Mesenteric Artery, Inferior; Mesenteric Veins; Muscle Contraction; Muscle, Smooth, Vascular; Potassium Chloride; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Pyrimidine Nucleotides; Receptors, Purinergic P2; Receptors, Purinergic P2X; Suramin; Uridine Triphosphate | 2000 |
Coexpression of several types of metabotropic nucleotide receptors in single cerebellar astrocytes.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Astrocytes; Calcium; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Intracellular Fluid; Pertussis Toxin; Protein Kinase C; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P2; Stimulation, Chemical; Suramin; Thionucleotides; Uridine Triphosphate; Virulence Factors, Bordetella | 2000 |
Effects of ATP on intracellular calcium dynamics of the perineurium of peripheral nerve bundles.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Anesthetics, Local; Animals; Antineoplastic Agents; Calcium; Enzyme Inhibitors; Glyburide; Hypoglycemic Agents; Lidocaine; Male; Microscopy, Confocal; Peripheral Nerves; Rats; Rats, Inbred WKY; Sciatic Nerve; Suramin; Tetraethylammonium; Tetrodotoxin; Thapsigargin; Triazines; Uridine Triphosphate | 2000 |
Nucleotide-evoked relaxation of rat vas deferens--a possible role for endogenous ATP released upon alpha(1)-adrenoceptor stimulation.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscle Relaxation; Norepinephrine; Nucleotides; Potassium; Purinergic P1 Receptor Antagonists; Pyridoxal Phosphate; Pyrophosphatases; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Suramin; Theophylline; Thionucleotides; Triazines; Vas Deferens; Vasoconstrictor Agents | 2001 |
ATP induces Ca(2+) signaling in human chondrons cultured in three-dimensional agarose films.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Antineoplastic Agents; Calcium Signaling; Cells, Cultured; Chondrocytes; Dose-Response Relationship, Drug; Fura-2; Humans; Sepharose; Suramin; Uridine Triphosphate | 2001 |
Suramin inhibits respiration and induces membrane permeability transition in isolated rat liver mitochondria.
Topics: Adenosine Diphosphate; Animals; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Membrane Permeability; Cell Respiration; Chelating Agents; Cyclosporine; Drug Interactions; Egtazic Acid; Enzyme Inhibitors; Ethylmaleimide; Intracellular Membranes; Magnesium; Membrane Potentials; Mitochondria, Liver; Mitochondrial Swelling; Oxygen Consumption; Rats; Rats, Wistar; Sulfhydryl Reagents; Suramin; Trypanocidal Agents | 2001 |
P2X2 receptor mediates stimulation of parasensory cation absorption by cochlear outer sulcus cells and vestibular transitional cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cations; Cochlea; Diffusion Chambers, Culture; Dose-Response Relationship, Drug; Flufenamic Acid; Gadolinium; Gerbillinae; Hearing; In Vitro Techniques; Ion Channels; Ion Transport; Microelectrodes; Physical Stimulation; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Suramin; Uridine Diphosphate; Uridine Triphosphate; Vestibule, Labyrinth; Vibration | 2001 |
Complementary role of extracellular ATP and adenosine in ischemic preconditioning in the rat heart.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Coloring Agents; Extracellular Space; Ischemic Preconditioning; Male; Microdialysis; Organic Chemicals; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Receptors, Purinergic P2; Suramin; Theophylline; Ventricular Function, Left; Ventricular Pressure | 2002 |
Purinergic receptor signaling at the basolateral membrane of macula densa cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Benzofurans; Calcium; Cytosol; Dose-Response Relationship, Drug; Estrenes; Female; Fura-2; Imidazoles; Kidney Glomerulus; Microscopy, Confocal; Pyrrolidinones; Rabbits; Receptors, Purinergic; Signal Transduction; Suramin; Thionucleotides; Uridine Triphosphate | 2002 |
ATP induces leukemia inhibitory factor mRNA in cultured rat astrocytes.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Central Nervous System; Dose-Response Relationship, Drug; Fetus; Growth Inhibitors; Interleukin-6; Leukemia Inhibitory Factor; Lymphokines; Microglia; Neurons; Neurotransmitter Agents; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Neurotransmitter; Receptors, Purinergic; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; RNA, Messenger; Suramin; Uridine Triphosphate | 2002 |
Enzyme kinetics and pharmacological characterization of nucleotidases released from the guinea pig isolated vas deferens during nerve stimulation: evidence for a soluble ecto-nucleoside triphosphate diphosphohydrolase-like ATPase and a soluble ecto-5'-nuc
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Calcium; Chromatography, High Pressure Liquid; Electric Stimulation; Enzyme Inhibitors; Guinea Pigs; In Vitro Techniques; Kinetics; Magnesium; Male; Nucleotidases; Phosphoric Diester Hydrolases; Phosphoric Monoester Hydrolases; Plant Proteins; Pyrophosphatases; Suramin; Sympathetic Nervous System; Vas Deferens | 2002 |
Human Ntera-2/D1 neuronal progenitor cells endogenously express a functional P2Y1 receptor.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Antineoplastic Agents; Blotting, Western; Calcium; Cell Membrane; Cells, Cultured; Cyclic AMP; Fluorescence; GTP-Binding Protein alpha Subunits, Gq-G11; Heterotrimeric GTP-Binding Proteins; Humans; Membrane Proteins; Mitogen-Activated Protein Kinases; Neurons; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Receptors, Purinergic P2Y2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stem Cells; Suramin; Thionucleotides; Uridine Triphosphate | 2002 |
Presence of diadenosine polyphosphates in the aqueous humor: their effect on intraocular pressure.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Aqueous Humor; Chromatography, High Pressure Liquid; Intraocular Pressure; Kinetics; Male; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rabbits; Structure-Activity Relationship; Suramin; Triazines | 2003 |
Neurotransmitters involved in the fast inhibitory junction potentials in mouse distal colon.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apamin; Colon; Dose-Response Relationship, Drug; Male; Membrane Potentials; Mice; Neuromuscular Junction; Neuropeptides; Neurotransmitter Agents; NG-Nitroarginine Methyl Ester; Peptide Fragments; Pituitary Adenylate Cyclase-Activating Polypeptide; Suramin; Tetrodotoxin; Thionucleotides | 2003 |
P2Y receptor specific for diadenosine tetraphosphate in lung: selective inhibition by suramin, PPADS, Ip5I, and not by MRS-2197.
Topics: Adenosine Diphosphate; Animals; Calcium Channel Blockers; Calcium Signaling; Cells, Cultured; Dinucleoside Phosphates; Epithelial Cells; Humans; Lung; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Suramin | 2003 |
ATP modulates intracellular Ca2+ and firing rate through a P2Y1 purinoceptor in cane toad pacemaker cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Biological Clocks; Blotting, Western; Bufo marinus; Calcium; Electrophysiology; Heart; Immunohistochemistry; Intracellular Membranes; Myocardium; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Sarcoplasmic Reticulum; Suramin; Thionucleotides; Type C Phospholipases | 2003 |
Expression of P2Y2 purinoceptors in MCG 101 murine sarcoma cells, and HT-29 human colon carcinoma cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antineoplastic Agents; Blotting, Western; Cell Line, Tumor; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Hydrogen-Ion Concentration; Immunohistochemistry; Mice; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Sarcoma; Suramin; Time Factors; Uridine Triphosphate | 2004 |
Adenosine 5'-triphosphate and noradrenaline are excitatory cotransmitters to the fibromuscular stroma of the guinea pig prostate gland.
Topics: Actins; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Atropine; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; Immunohistochemistry; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Prazosin; Prostate; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2X2; Receptors, Purinergic P2X4; Suramin; Tetrodotoxin; Thionucleotides | 2004 |
Characterization of ATP and ADP hydrolysis activity in rat gastric mucosa.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Calcium; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gastric Mucosa; Hydrogen-Ion Concentration; Hydrolysis; In Vitro Techniques; Magnesium; Male; Rats; Rats, Wistar; Sodium Azide; Substrate Specificity; Suramin; Vanadates | 2005 |
Dual presynaptic control by ATP of glutamate release via facilitatory P2X1, P2X2/3, and P2X3 and inhibitory P2Y1, P2Y2, and/or P2Y4 receptors in the rat hippocampus.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Astrocytoma; Calcium; Cell Line; Cell Line, Tumor; Glutamic Acid; Hippocampus; Kidney; Male; Potassium; Pyramidal Cells; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Presynaptic; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2X2; Receptors, Purinergic P2X3; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y2; Recombinant Fusion Proteins; RNA, Messenger; Subcellular Fractions; Suramin; Synaptosomes; Transfection; Triazines; Triazoles; Xanthines | 2005 |
The novel suramin analogue NF864 selectively blocks P2X1 receptors in human platelets with potency in the low nanomolar range.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Apyrase; Blood Platelets; Calcium; Cell Shape; Dose-Response Relationship, Drug; Humans; Least-Squares Analysis; Linear Models; Phenylmercury Compounds; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2Y1; Suramin; Thionucleotides | 2005 |
Changes in purinergic signalling in developing and ageing rat tail artery: importance for temperature control.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aging; Animals; Arteries; Dose-Response Relationship, Drug; Electric Stimulation; Immunohistochemistry; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Norepinephrine; Prazosin; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Regional Blood Flow; Signal Transduction; Suramin; Tail; Thionucleotides; Uridine Triphosphate | 2006 |
Ecto-nucleotide pyrophosphatase/phosphodiesterase as part of a multiple system for nucleotide hydrolysis by platelets from rats: kinetic characterization and biochemical properties.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Angiotensin II; Animals; Blood Platelets; Gadolinium; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Male; Nucleotides; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyrophosphatases; Rats; Rats, Wistar; Signal Transduction; Sodium Azide; Suramin; Thymidine Monophosphate | 2006 |
Alterations of adenine nucleotide metabolism and function of blood platelets in patients with diabetes.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amino Acids; Blood Platelets; Diabetes Mellitus; Dose-Response Relationship, Drug; Female; Humans; Hyperglycemia; Male; Middle Aged; Platelet Aggregation; Suramin; Thiobarbituric Acid Reactive Substances; Thrombin | 2007 |
Activation-dependent trafficking of NTPDase2 in Chinese hamster ovary cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Calcium; Cell Membrane; CHO Cells; Cricetinae; Cricetulus; Green Fluorescent Proteins; Hydrolysis; Intracellular Fluid; Microscopy, Confocal; Protein Transport; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2; Recombinant Fusion Proteins; Suramin; Time Factors; Transfection; Uridine Diphosphate; Uridine Triphosphate | 2007 |
Directed molecular screening for RecA ATPase inhibitors.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Binding Sites; Biological Assay; DNA Gyrase; Drug Evaluation, Preclinical; Enzyme Inhibitors; Escherichia coli; Fluorescent Dyes; Hydrolysis; Nucleotides; Protein-Tyrosine Kinases; Rec A Recombinases; Sensitivity and Specificity; Suramin; Time Factors | 2007 |
Vesicular ATP is the predominant cause of intercellular calcium waves in astrocytes.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aniline Compounds; Animals; Apyrase; Astrocytes; Brefeldin A; Calcium; Calcium Signaling; Cells, Cultured; Cytoplasmic Vesicles; Diffusion; Enzyme Inhibitors; Fluorescent Dyes; Hippocampus; Macrolides; Neurons; Paracrine Communication; Proton-Translocating ATPases; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Suramin; Time Factors; Xanthenes | 2007 |
Inhibition of human and mouse plasma membrane bound NTPDases by P2 receptor antagonists.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Antigens, CD; Aorta, Thoracic; Apyrase; Benzenesulfonates; Cell Membrane; Chlorocebus aethiops; COS Cells; Humans; Hydrolysis; Mice; Mice, Knockout; Purinergic P2 Receptor Antagonists; Recombinant Proteins; Suramin; Transfection; Triazines | 2007 |
E-NTPDases and ecto-5'-nucleotidase expression profile in rat heart left ventricle and the extracellular nucleotide hydrolysis by their nerve terminal endings.
Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Extracellular Space; Gene Expression Profiling; Heart Ventricles; Hydrogen-Ion Concentration; Hydrolysis; Isoenzymes; Kinetics; Male; Myocardium; Nerve Endings; Nucleotides; Ouabain; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Sodium Azide; Suramin; Synaptosomes | 2008 |
Ca2+ signaling in injured in situ endothelium of rat aorta.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Aorta, Abdominal; Aorta, Thoracic; Calcium Signaling; Endothelium, Vascular; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rats; Receptors, Purinergic P2; Suramin | 2008 |
Dinucleotide polyphosphates contribute to purinergic signalling via inhibition of adenylate kinase activity.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylate Kinase; Cells, Cultured; Dinucleoside Phosphates; Humans; Nucleotides; Signal Transduction; Suramin | 2008 |
Adenine nucleotide changes in the remnant liver: An early signal for regeneration after partial hepatectomy.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Biomarkers; Blood Glucose; Hepatectomy; Liver; Liver Regeneration; Male; Mitochondria, Liver; Phentolamine; Proto-Oncogene Proteins c-fos; Purinergic Antagonists; Rats; Rats, Sprague-Dawley; Signal Transduction; Suramin | 2008 |
P2Y receptors mediate Ca2+ signaling in duodenocytes and contribute to duodenal mucosal bicarbonate secretion.
Topics: Adenosine Diphosphate; Aminoquinolines; Animals; Bicarbonates; Boron Compounds; Calcium Channel Blockers; Calcium Signaling; Cell Line; Dogs; Duodenum; Epithelial Cells; Estrenes; Female; Hydrogen-Ion Concentration; Intestinal Mucosa; Intestinal Secretions; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; Nifedipine; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Pyrrolidinones; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Suramin; Time Factors; Uridine Triphosphate | 2009 |
CrATP as a new inhibitor of ecto-ATPases of trypanosomatids.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Enzyme Inhibitors; Suramin; Time Factors; Trypanosomatina | 2009 |
Investigation of the role of adrenergic and non-nitrergic, non-adrenergic neurotransmission in the sheep isolated internal anal sphincter.
Topics: Adenosine Diphosphate; Adrenergic alpha-Antagonists; Anal Canal; Animals; Anti-Arrhythmia Agents; Apamin; Bretylium Compounds; Electric Stimulation; Enzyme Inhibitors; Epinephrine; Humans; Muscle Contraction; Muscle Tonus; Neurotransmitter Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Prazosin; Sheep; Stress, Mechanical; Suramin; Synaptic Transmission | 2009 |
Activation of purinergic receptors by ATP induces ventricular tachycardia by membrane depolarization and modifications of Ca2+ homeostasis.
Topics: Action Potentials; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Calcium; In Vitro Techniques; Membrane Potentials; Mice; Microscopy, Confocal; Myocytes, Cardiac; Patch-Clamp Techniques; Purinergic Agonists; Pyridoxal Phosphate; Receptors, Purinergic; Suramin; Tachycardia, Ventricular | 2009 |
Interaction of new, very potent non-nucleotide antagonists with Arg256 of the human platelet P2Y12 receptor.
Topics: Adenosine Diphosphate; Animals; Arginine; Binding, Competitive; CHO Cells; Cloning, Molecular; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Cyclic AMP Response Element Modulator; Humans; Isomerism; Luciferases; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Sulfonic Acids; Suramin; Thionucleotides; Triazines | 2009 |
Assessment and characterization of purinergic contractions and relaxations in the rat urinary bladder.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Drug Antagonism; Electric Stimulation; Glyburide; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Suramin; Theophylline; Uracil Nucleotides; Urinary Bladder; Xanthines | 2010 |
Purine receptors modulate chondrocyte extracellular inorganic pyrophosphate production.
Topics: Adenosine Diphosphate; Animals; Cartilage, Articular; Cells, Cultured; Chondrocytes; Cyclic AMP; Diphosphates; Purinergic P1 Receptor Agonists; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic; RNA, Messenger; Suramin; Swine | 2010 |
Mechanical stress-induced interleukin-1beta expression through adenosine triphosphate/P2X7 receptor activation in human periodontal ligament cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Diphosphate; Adenosine Triphosphate; Apyrase; Benzenesulfonates; Calcium Channel Blockers; Calcium Signaling; Cell Culture Techniques; Cell Survival; Cells, Cultured; Coloring Agents; Dactinomycin; Homeostasis; Humans; Interleukin-1beta; Luminescent Measurements; Periodontal Ligament; Purinergic P2X Receptor Antagonists; Receptors, Purinergic P2X7; RNA, Small Interfering; Signal Transduction; Stress, Mechanical; Suramin; Tetrazolium Salts; Thiazoles; Time Factors; Up-Regulation | 2013 |
A new family of covalent inhibitors block nucleotide binding to the active site of pyruvate kinase.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arginine; Benzoates; Catalytic Domain; Conserved Sequence; Crystallography, X-Ray; Enzyme Inhibitors; High-Throughput Screening Assays; Humans; Isoenzymes; Leishmania mexicana; Lysine; Models, Molecular; Protein Binding; Protein Conformation; Pyruvate Kinase; Recombinant Proteins; Saccharin; Species Specificity; Structure-Activity Relationship; Suramin | 2012 |
Characterization of ecto-ATPase activity in the surface of LLC-PK1 cells and its modulation by ischemic conditions.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Antineoplastic Agents; Cells, Cultured; Hydrogen-Ion Concentration; Hydrolysis; Ischemia; Kidney Tubules, Proximal; Kinetics; L-Lactate Dehydrogenase; LLC-PK1 Cells; Suramin; Swine | 2012 |
ADP is a vasodilator component from Lasiodora sp. mygalomorph spider venom.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Animals; Blotting, Western; Chemical Fractionation; Endothelium; In Vitro Techniques; Mass Spectrometry; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nuclear Magnetic Resonance, Biomolecular; Phosphorylation; Rats; Spider Venoms; Spiders; Suramin; Vasodilation; Vasodilator Agents | 2013 |
Gravity loading induces adenosine triphosphate release and phosphorylation of extracellular signal-regulated kinases in human periodontal ligament cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Apyrase; Calcium; Cell Culture Techniques; Cells, Cultured; Centrifugation; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Gingiva; Gravitation; Humans; Periodontal Ligament; Phosphorylation; Purinergic Agonists; Purinergic Antagonists; Purinergic P2X Receptor Antagonists; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2; Signal Transduction; Stress, Mechanical; Suramin | 2014 |
Plasma ATP is required for neutrophil activation in a mouse sepsis model.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Disease Models, Animal; Male; Mice, Inbred C57BL; Neutrophil Activation; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Sepsis; Suramin | 2014 |
Uridine adenosine tetraphosphate is a novel neurogenic P2Y1 receptor activator in the gut.
Topics: Adenosine Diphosphate; Animals; Antineoplastic Agents; Colon; Deoxyadenine Nucleotides; Dinucleoside Phosphates; Gastrointestinal Motility; Humans; Mice; Mice, Knockout; Muscle Relaxation; Muscle, Smooth; Purinergic P2Y Receptor Agonists; Receptors, Purinergic P2Y1; Small-Conductance Calcium-Activated Potassium Channels; Suramin; Uridine Diphosphate | 2014 |
Enhancement of acid-sensing ion channel activity by metabotropic P2Y UTP receptors in primary sensory neurons.
Topics: Acid Sensing Ion Channels; Acidosis; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Ganglia, Spinal; Male; Membrane Potentials; Pain; Pain Measurement; Protons; Purinergic P2Y Receptor Agonists; Purinergic P2Y Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2Y1; Sensory Receptor Cells; Signal Transduction; Suramin; Uridine Triphosphate | 2016 |
Characterization of E-NTPDase (EC 3.6.1.5) activity in hepatic lymphocytes: A different activity profile from peripheral lymphocytes.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Blood Cells; Calcium; Cations, Divalent; Cell Separation; Enzyme Assays; Enzyme Inhibitors; Gene Expression; Hydrogen-Ion Concentration; Kinetics; Liver; Lymphocytes; Male; Organ Specificity; Ouabain; Rats; Rats, Wistar; Sodium Azide; Substrate Specificity; Suramin; Vanadates | 2017 |
Nucleotide transmitters ATP and ADP mediate intercellular calcium wave communication via P2Y12/13 receptors among BV-2 microglia.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Biomechanical Phenomena; Boron Compounds; Calcium; Calcium Signaling; Cell Communication; Cell Line, Transformed; Gene Expression; Inositol Phosphates; Mechanotransduction, Cellular; Mice; Microglia; Molecular Imaging; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Suramin; Thapsigargin | 2017 |
Activation of retinal glial (Müller) cells by extracellular ATP induces pronounced increases in extracellular H+ flux.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Diphosphate; Adenosine Triphosphate; Ambystoma; Animals; Ependymoglial Cells; Extracellular Fluid; Humans; Hydrogen-Ion Concentration; Ictaluridae; In Vitro Techniques; Ion Transport; Lampreys; Macaca fascicularis; Macaca mulatta; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2Y; Retina; Signal Transduction; Skates, Fish; Suramin | 2018 |
Contribution of ATP-Mediated Positive Feedback to Sympathetic Nerve-Induced Positive Inotropy in Guinea Pig Ventricular Myocardium.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Feedback, Physiological; Guinea Pigs; Heart Ventricles; Male; Muscle Contraction; Norepinephrine; Papillary Muscles; Prazosin; Propranolol; Pyridoxal Phosphate; Suramin; Sympathetic Nervous System; Ventricular Function | 2021 |