Compounds > adenosine diphosphate
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adenosine diphosphate and monastrol

adenosine diphosphate has been researched along with monastrol in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's10 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kapitein, LC; Kapoor, TM; Kim, JH; Kwok, BH; Peterman, EJ; Schmidt, CF1
Kapoor, TM; Maliga, Z; Mitchison, TJ1
Blangy, A; Crevel, I; Cross, R; DeBonis, S; Ebel, C; Gans, P; Hackney, DD; Kozielski, F; Lebeau, L; Simorre, JP; Skoufias, DA; Wade, RH1
Buser, CA; Halczenko, W; Hartman, GD; Homnick, C; Huber, HE; Kuo, LC; Sardana, V; Schaber, M; Xu, B; Yan, Y1
Alonso, MC; Crevel, IM; Cross, RA1
Alford, SR; Dalrymple, NA; Kim, S; Walker, RA; Wojcik, EJ1
Carson, JD; Copeland, RA; Dhanak, D; Huang, PS; Jackson, JR; Lee, Y; Luo, L; Sakowicz, R1
Cochran, JC; Gatial, JE; Gilbert, SP; Kapoor, TM1
Gilbert, SP; Gross, H; Hoenger, A; Krzysiak, TC; Sproul, LR; Tittmann, P; Wendt, T1
Basso, A; Duca, JS; Gray, K; Le, HV; Lesburg, CA; Mannarino, AF; Nale, L; Ogas, P; Prongay, AJ; Sheth, PR1

Other Studies

10 other study(ies) available for adenosine diphosphate and monastrol

ArticleYear
Allosteric inhibition of kinesin-5 modulates its processive directional motility.
    Nature chemical biology, 2006, Volume: 2, Issue:9

    Topics: Allosteric Regulation; Animals; Antimitotic Agents; Green Fluorescent Proteins; Kinesins; Microscopy, Fluorescence; Microtubules; Pyrimidines; Recombinant Fusion Proteins; Spindle Apparatus; Thiones; Xenopus laevis; Xenopus Proteins

2006
Evidence that monastrol is an allosteric inhibitor of the mitotic kinesin Eg5.
    Chemistry & biology, 2002, Volume: 9, Issue:9

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Allosteric Regulation; Animals; Cells, Cultured; Chlorocebus aethiops; Enzyme Inhibitors; Fluorescent Dyes; Humans; Hydrolysis; Kidney; Kinesins; Kinetics; Microtubules; Models, Biological; Protein Structure, Tertiary; Pyrimidines; Spectrometry, Fluorescence; Stereoisomerism; Thiones; Xenopus Proteins

2002
Interaction of the mitotic inhibitor monastrol with human kinesin Eg5.
    Biochemistry, 2003, Jan-21, Volume: 42, Issue:2

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cattle; Dose-Response Relationship, Drug; Dyneins; Enzyme Activation; Growth Inhibitors; HeLa Cells; Humans; Inhibitory Concentration 50; Kinesins; Microscopy, Interference; Microscopy, Video; Microtubules; Nuclear Magnetic Resonance, Biomolecular; ortho-Aminobenzoates; Peptide Fragments; Protein Structure, Tertiary; Pyrimidines; Sequence Deletion; Sodium Chloride; Stereoisomerism; Thiones

2003
Inhibition of a mitotic motor protein: where, how, and conformational consequences.
    Journal of molecular biology, 2004, Jan-09, Volume: 335, Issue:2

    Topics: Adenosine Diphosphate; Binding Sites; Crystallization; Crystallography, X-Ray; Humans; Kinesins; Magnesium; Microtubules; Mitosis; Models, Molecular; Molecular Motor Proteins; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Pyrimidines; Structure-Activity Relationship; Thiones

2004
Monastrol stabilises an attached low-friction mode of Eg5.
    Current biology : CB, 2004, Jun-08, Volume: 14, Issue:11

    Topics: Adenosine Diphosphate; Animals; Kinesins; Microtubules; Pyrimidines; Rats; Thiones; Xenopus; Xenopus Proteins

2004
Disparity in allosteric interactions of monastrol with Eg5 in the presence of ADP and ATP: a difference FT-IR investigation.
    Biochemistry, 2004, Aug-10, Volume: 43, Issue:31

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Allosteric Regulation; Amides; Amino Acid Sequence; Binding Sites; Humans; Kinesins; Macromolecular Substances; Molecular Sequence Data; Nitrobenzenes; Phosphates; Photolysis; Protein Binding; Pyrimidines; Spectroscopy, Fourier Transform Infrared; Thiones

2004
Mechanism of inhibition of human KSP by monastrol: insights from kinetic analysis and the effect of ionic strength on KSP inhibition.
    Biochemistry, 2004, Dec-07, Volume: 43, Issue:48

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Catalysis; Catalytic Domain; Dose-Response Relationship, Drug; Humans; Kinesins; Kinetics; Microtubules; Osmolar Concentration; Protein Binding; Protein Conformation; Pyrimidines; Spectrometry, Fluorescence; Thiones

2004
Monastrol inhibition of the mitotic kinesin Eg5.
    The Journal of biological chemistry, 2005, Apr-01, Volume: 280, Issue:13

    Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Dose-Response Relationship, Drug; Humans; Hydrolysis; Kinesins; Kinetics; Microtubules; Models, Biological; Models, Chemical; Nucleotides; Protein Binding; Protein Conformation; Pyrimidines; Spindle Apparatus; Thiones; Time Factors

2005
A structural model for monastrol inhibition of dimeric kinesin Eg5.
    The EMBO journal, 2006, May-17, Volume: 25, Issue:10

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cryoelectron Microscopy; Dimerization; Humans; Kinesins; Microtubules; Models, Molecular; Protein Structure, Quaternary; Pyrimidines; Rats; Thiones; Tubulin

2006
Thermodynamics of nucleotide and inhibitor binding to wild-type and ispinesib-resistant forms of human kinesin spindle protein.
    Biochemistry, 2009, Nov-24, Volume: 48, Issue:46

    Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acid Substitution; Benzamides; Biocatalysis; Calorimetry; Circular Dichroism; Drug Resistance, Neoplasm; Enzyme Inhibitors; Humans; Kinesins; Kinetics; Magnesium; Models, Molecular; Nucleotides; Protein Binding; Protein Structure, Tertiary; Pyrimidines; Quinazolines; Recombinant Fusion Proteins; Temperature; Thermodynamics; Thiones; Transition Temperature

2009