adenosine diphosphate has been researched along with glutamic acid in 180 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 35 (19.44) | 18.7374 |
| 1990's | 45 (25.00) | 18.2507 |
| 2000's | 71 (39.44) | 29.6817 |
| 2010's | 26 (14.44) | 24.3611 |
| 2020's | 3 (1.67) | 2.80 |
| Authors | Studies |
|---|---|
| Gutmann, M; Hoischen, C; Krämer, R | 1 |
| Dean, DR; Howard, JB; Wolle, D | 1 |
| Bryła, J; Jarzyna, R; Lietz, T; Michalik, M; Pietkiewicz, J | 1 |
| Chen, ZD; Colman, RF; Haeffner-Gormley, L; Zalkin, H | 1 |
| Jani, MS; Katyare, SS; Telang, SD | 1 |
| Ghijsen, WE; Lopes da Silva, FH; Verhage, M | 1 |
| Dierks, T; Krämer, R; Salentin, A | 1 |
| Dierks, T; Heberger, C; Krämer, R; Salentin, A | 1 |
| Enriquez, JA; Hernandez-Yago, J; López-Pérez, MJ; Muiño Blanco, MT; Sánchez-Prieto, J | 1 |
| Berson, A; Fisch, C; Fromenty, B; Larrey, D; Letteron, P; Pessayre, D | 1 |
| Krämer, R; Lambert, C | 1 |
| Arce, C; Cañadas, S; Castro, E; González, MP; Oset-Gasque, MJ | 1 |
| Biagetti, L; Caldarera, CM; Cattabriga, I; Colì, G; Finelli, C; Galeazzi, M; Guarnieri, C; Muscari, C; Turinetto, B | 1 |
| Battelli, D; Bellei, M; Bobyleva-Guarriero, V; DiLisa, F; Guarriero, DM; Muscatello, U; Siliprandi, N | 1 |
| Inubushi, T; Li, LY; Meister, A; Seddon, AP | 1 |
| Lin, M; Plaxton, WC; Turpin, DH | 1 |
| Aubry, C; Dupuy, G; Lespinas, F; Revol, F | 1 |
| Kleinholz, M; Myers, RE; Wagner, KR | 1 |
| Meister, A; Seddon, AP; Zhao, KY | 1 |
| Jung, K | 1 |
| Alvarez, M; Bracht, A; Kelmer Bracht, A | 1 |
| Jung, K; Pergande, M | 2 |
| Heikkila, RE; Nicklas, WJ; Vyas, I | 1 |
| Byrne, E; Trounce, I | 1 |
| Nissim, I; Segal, S; Yudkoff, M | 1 |
| Kauppinen, RA; Nicholls, DG | 1 |
| Mörikofer-Zwez, S; Stoecklin, FB; Walter, P | 1 |
| Kaminsky, YG; Kosenko, EA | 1 |
| Bailey, JM; Colman, RF | 1 |
| Jung, K; Reinholdt, C | 1 |
| Balaban, RS; Koretsky, AP | 1 |
| González, P; Sánchez-Prieto, J | 1 |
| Walker, JB; Woznicki, DT | 1 |
| Dierks, T; Krämer, R; Riemer, E | 1 |
| Kauppinen, RA; McMahon, HT; Nicholls, DG | 1 |
| Griffith, OW; Meister, A | 1 |
| Horton, AA; Spencer, JA | 1 |
| Cook, PF | 1 |
| Cunarro, JA; Johnson, WA; Schultz, SE; Weiner, MW | 1 |
| Ballantyne, SR; Goldstein, S; Moerman, EJ; Robson, AL | 1 |
| Makarewicz, W; Swierczyński, J | 1 |
| Borgatti, AR; Pagliarani, A; Trigari, G; Ventrella, V | 1 |
| Hamman, HC; Haynes, RC | 1 |
| Allison, RD; Purich, DL | 1 |
| Dennig, G; Sieghart, W | 1 |
| Aitchison, MJ; Engel, PC; Hornby, DP | 1 |
| Aiyar, AS; Gopalaswamy, UV | 1 |
| Kauppinen, RA | 1 |
| Inomoto, T; Jin, MB; Kitai, T; Mori, S; Ozawa, K; Sato, B; Tanaka, A; Tokuka, A; Yamaoka, Y; Yanabu, N | 1 |
| Ichihara, K; Nakai, T; Satoh, K | 1 |
| Panov, AV; Scaduto, RC | 1 |
| Grady, C; Gupta, S; Ruderman, NB; Schultz, V; Sussman, I; Tornheim, K | 1 |
| Albuquerque, C; Coutinho-Silva, R; Oliveira, SM; Oliveira-Castro, GM; Persechini, PM | 1 |
| Gurevich, VS; Mikhaĭlova, IA; Popov, IuG | 1 |
| Bryła, J; Erecińska, M; Michalik, M; Nelson, J | 1 |
| Colman, RF; Wrzeszczynski, KO | 1 |
| Johnson, RB; Murphy, S; Napychank, PA; Snyder, EL | 1 |
| Konji, VN; Lomo, PO; Makawiti, DW | 1 |
| Burgesser, K; Madl, JE | 1 |
| Eisenberg, D; Kuo, I; Liaw, SH | 1 |
| Hoshino, S; Katada, T; Maehama, T | 1 |
| Akutsu, H; Amano, T; Matsui, T; Ohbuchi, H; Tozawa, K; Yagi, H; Yoshida, M | 1 |
| Katayama, T; Kurokawa, K; Miki, T; Mizushima, T; Nishida, S; Sekimizu, K | 1 |
| Besselsen, E; Breukel, AI; Ghijsen, WE; Lopes da Silva, FH | 1 |
| Ambrósio, AF; Carvalho, AP; Carvalho, CM; Malva, JO; Sequeira, SM | 1 |
| Nicholls, DG; Pocock, JM | 1 |
| Eisenberg, E; Greene, L; Rajapandi, T; Wu, C | 1 |
| Friedman, AL; Geeves, MA; Manstein, DJ; Spudich, JA | 1 |
| Blair, PS; Katz, ML; Savill, JD; Siakotos, AN | 1 |
| Chesselet, MF; Erecinska, M; McLaughlin, BA; Nelson, D; Silver, IA | 1 |
| Andersen, JP; Vilsen, B | 1 |
| Roudiak, SG; Shrader, TE | 1 |
| Balaban, RS; French, SA; Territo, PR | 1 |
| Attardi, G; Greco, M; Papa, S; Villani, G | 1 |
| Cadena, SM; Carnieri, EG; de Oliveira, MB; Echevarria, A | 1 |
| Grafe, P; Hanemann, CO; Kamleiter, M; Kluwe, L; Mayer, C; Rosenbaum, C; Sanchez-Brandelik, R | 1 |
| Burnstock, G; Ralevic, V; Spyer, KM; Thomas, T | 1 |
| Fannin, SW; Hassan, MO; Hoppel, CL; Lesnefsky, EJ; Slabe, TJ | 1 |
| Brustovetsky, N; Dubinsky, JM | 2 |
| Dave, KR; Katyare, SS; Swegert, CV | 1 |
| Boeck, CR; Bronzatto, MJ; Sarkis, JJ; Souza, DG; Vendite, D | 1 |
| Burgess, BK; Bursey, EH; Ribbe, MW | 1 |
| Araki, T; Asakura, H; Koshino, T; Nakai, A; Oya, A; Taniuchi, Y; Yokota, A | 1 |
| Anderson, MF; Hobbs, LM; Kong, JY; Phillips, S; Powell, JA; Sims, NR; Zaidan, E | 1 |
| Argüello, JM; Berlin, JR; Lingrel, JB; Peluffo, RD | 1 |
| Knowles, VL; Plaxton, WC; Smith, CR | 1 |
| Chen, W; Crampton, DJ; Frasch, WD; Hu, CY | 1 |
| Metaxari, M; Plaitakis, A; Shashidharan, P | 1 |
| Plaxton, WC; Turner, WL | 1 |
| Joshi, NB; Joshi, PG; Kannurpatti, SS | 1 |
| Fang, J; Peterson, PE; Schmidt, T; Smith, TJ; Stanley, CA | 1 |
| Janiak-Spens, F; Pham, AS; Reinhart, GD | 1 |
| Agam, G; Belmaker, RH; Shaldubina, A | 1 |
| De La Cruz, EM; Ostap, EM; Sweeney, HL | 1 |
| Aguilar, JS; Oaknin, S; Ramos, A; Rodríguez-Ferrer, CR; Rotllán, P | 1 |
| Plaitakis, A; Zaganas, I | 1 |
| Georgopoulos, P; Plaitakis, A; Schousboe, A; Sonnewald, U; Waagepetersen, HS; Zaganas, I | 1 |
| Jacobsen, MD; Jorgensen, PL; Pedersen, PA | 1 |
| Khogali, SE; Pringle, SD; Rennie, MJ; Weryk, BV | 1 |
| Fang, J; Hsu, BY; MacMullen, CM; Poncz, M; Smith, TJ; Stanley, CA | 1 |
| Battastini, AM; Bonan, CD; Bruno, AN; Sarkis, JJ; Wofchuk, ST | 1 |
| Bognar, AL; Cross, JA; Shen, Y; Sheng, Y; Smith, CA | 1 |
| Toustrup-Jensen, M; Vilsen, B | 1 |
| Bole, DG; Ikemoto, A; Ueda, T | 1 |
| Buettger, CW; Carr, RD; Collins, HW; Doliba, NM; Matschinsky, FM; Qin, W; Vatamaniuk, MZ; Wehrli, SL | 1 |
| Chen, J; Li, H; Li, Y; Lin, J | 1 |
| Brendza, KM; Gilbert, SP; Hoenger, A; Klumpp, LM; Rosenberg, JM | 1 |
| Antunes Soares, FA; Dall'Onder, LP; Frizzo, ME; Lara, DR; Souza, DO; Swanson, RA | 1 |
| Boehm, S; Freissmuth, M; Just, H; Klinger, M; Korkhov, VM; Kudlacek, O; Nanoff, C; Pankevych, H; Vartian, N; Yang, Q | 1 |
| Cho, SW; Choi, SY; Huh, JW; Kim, MJ; Kim, TU; Lee, WJ; Yang, SJ | 1 |
| Cole, SP; Deeley, RG; Gao, M; Payen, LF; Westlake, CJ | 1 |
| Balasubramanian, S; Katyare, SS; Parmar, DV | 1 |
| Bonete, MJ; Díaz, S; Ferrer, J; Oren, A; Pérez-Pomares, F | 1 |
| Anagnostopoulos, PV; Filis, KA; Katsamouris, A; Pipinos, II; Sabbah, HN; Sharov, VG; Shepard, AD; Todor, A | 1 |
| Cheung, NS; Halliwell, B; Lim, BG; Tan, J; Vincent, AS; Whiteman, M; Wong, KP | 1 |
| Allison, WS; Bandyopadhyay, S | 1 |
| Brendza, KM; Gatial, JE; Gilbert, SP; Hoenger, A; Klumpp, LM; Saxton, WM | 1 |
| Kunz, WS; Wallesch, CW; Wiedemann, FR; Winkler-Stuck, K | 1 |
| Inesi, G; Lewis, D; Ma, H; Xu, C | 1 |
| Bartholomew, LA; Senior, AE; Tombline, G; Urbatsch, IL | 1 |
| Angelini, GD; Caputo, M; Modi, P; Parry, AJ; Pawade, A; Reeves, B; Suleiman, MS | 1 |
| Bartholomew, LA; Gimi, K; Senior, AE; Tombline, G; Tyndall, GA; Urbatsch, IL | 1 |
| Andersen, JP; Clausen, JD; Jensen, AM; Møller, JV; Nissen, P; Sørensen, TL; Vilsen, B | 1 |
| Bowser, DN; Khakh, BS | 1 |
| Lampert, E; Mettauer, B; N'guessan, B; Ponsot, E; Ribera, F; Richard, R; Veksler, V; Ventura-Clapier, R; Zoll, J | 1 |
| Basso, LA; Canduri, F; de Azevedo, WF; de Oliveira, JS; Dias, MV; Palma, MS; Pereira, JH; Santos, DS | 1 |
| Eimre, M; Gellerich, FN; Kõvask, S; Orlova, E; Paju, K; Peet, N; Piirsoo, A; Ress, M; Saks, VA; Seppet, E; Seppet, EK; Zierz, S | 1 |
| Atkins, WM; Dabrowski, MJ; Kung, I; Pearson, JT | 1 |
| Junge, W; Nelson, N | 1 |
| Andreyev, AY; Kushnareva, YE; Murphy, AN; Ward, MW; Wiley, SE | 1 |
| Boeck, CR; Bronzatto, MJ; Kroth, EH; Vendite, D | 1 |
| Almeida, T; Cunha, RA; Oliveira, CR; Richardson, PJ; Rodrigues, RJ | 1 |
| Kannan, N; Neuwald, AF | 1 |
| Adachi, T; Brosenitsch, TA; Funk, GD; Housley, GD; Lipski, J | 1 |
| Auerbach, SD; Johnson, KA | 1 |
| Bos, IW; de Graan, PN; Hoogland, G; Kupper, F; Spierenburg, HA; van Nieuwenhuizen, O; van Willigen, G | 1 |
| Helps, SC; Nilsson, M; Sims, NR; Thoren, AE | 1 |
| Danziger, O; Horovitz, A; Shimon, L | 1 |
| Feldkamp, T; Kribben, A; Ostrowski, T; Roeser, NF; Weinberg, JM | 1 |
| Barnes, BD; Olsen, ME; Starnes, JW | 1 |
| Allen, A; Li, M; Smith, TJ | 1 |
| Liu, XH; Ruan, HZ; Wu, XG; Zeng, JW; Zhang, JH | 1 |
| Ishida, A; Noda, Y; Ueda, T | 1 |
| Du, L; He, WJ; Liu, XH; Ruan, HZ; Wu, XG; Zeng, JW; Zhang, JH | 1 |
| Franke, H; Gerevich, Z; Illés, P; Kittner, H; Köles, L; Krügel, U | 1 |
| He, WJ; Hu, ZA; Liu, XH; Ruan, HZ; Xiao, Z; Zeng, JW; Zhao, YD | 1 |
| Butt, AM; Hamilton, N; Vayro, S; Wigley, R | 1 |
| Gaspar, I; Szabad, J | 1 |
| Alano, CC; Anderson, CM; Hunt, WT; Shao, Z; Suh, SW; Swanson, RA; Tang, KS | 1 |
| Anderson, CA; Anderson, EJ; Kypson, AP; Lehr, EJ; Neufer, PD; Rodriguez, E | 1 |
| Arandarcikaite, O; Gellerich, FN; Gizatullina, Z; Jerzembek, D; Seppet, E; Striggow, F; Vielhaber, S | 1 |
| Antonilli, L; Brusadin, V; Catalano, M; Chece, G; Cipriani, R; Eusebi, F; Fredholm, BB; Lauro, C; Limatola, C; Trettel, F; van Rooijen, N | 1 |
| Gnyawali, S; Khanna, S; Peterson, L; Rink, C | 1 |
| Marchik, EI; Samartsev, VN; Shamagulova, LV | 1 |
| Delicado, EG; Ortega, F; Pérez-Sen, R; Teresa Miras-Portugal, M | 1 |
| Dark, A; Davies, JM; Demidchik, V; Richards, SL; Shabala, S | 1 |
| Berger, J; Brodde, A; Brugger, B; Just, WW; Lehmann, WD; Teigler, A; Wieland, F | 1 |
| Audoly, G; Cambillau, C; Cascales, E; Derrez, E; Durand, E; Ortiz-Lombardia, M; Raoult, D; Spinelli, S | 1 |
| Takeda, K; Ueda, T | 1 |
| Amaral, AU; Busanello, EN; Tonin, AM; Vargas, CR; Viegas, CM; Wajner, M; Zanatta, A | 1 |
| Brochier, AW; Camacho-Pereira, J; de Souza, DO; Galina, A; Gnoatto, J; Haas, CB; Muller, AP; Portela, LV; Zimmer, ER | 1 |
| Bratus', LV; Koliesnikova, IeE; Nosar, VI | 1 |
| Bringmann, A; Chen, J; Grosche, A; Pannicke, T; Reichenbach, A; Wiedemann, P | 1 |
| Barcomb, K; Bayer, KU; Coultrap, SJ | 1 |
| Man'ko, BO; Man'ko, VV | 1 |
| Buck, M; Burrows, PC; Darbari, VC; Joly, N; Lawton, E; Lu, D; Wiesler, S; Zhang, N; Zhang, X | 1 |
| Fedinec, AL; Leffler, CW; Liu, J; Parfenova, H | 1 |
| Cho, JH; Choi, IS; Jang, IS; Lee, MG | 1 |
| Cristóvão, G; Cunha, RA; George, J; Gomes, CA; Gonçalves, FQ; Gonçalves, T; Meyer Fernandes, JR; Rodrigues, L | 1 |
| Bouitbir, J; Charton, A; Geny, B; Jimenez, L; Klein, A; Péronnet, FR; Richard, R; Sirvent, P; Zoll, J | 1 |
| Amaral, AU; Castilho, RF; Cecatto, C; Wajner, M | 1 |
| Smith, HQ; Smith, TJ | 1 |
| Du, H; Gauba, E; Guo, L | 1 |
| Barbosa, RM; Laranjinha, J; Ledo, A; Lourenço, CF | 1 |
| Adler-Gunzelmann, G; Behrens, VA; Henn, A; Latham, SL; Münnich, S; Taft, MH; Thiel, C | 1 |
| Belenyuk, VD; Borisov, AG; Moshev, AV; Savchenko, AA | 1 |
| Amaral, AU; Marschner, RA; Ribeiro, RT; Roginski, AC; Wajner, M; Wajner, SM; Zemniaçak, ÂB | 1 |
| Aleshin, VA; Bellinzoni, M; Bruch, EM; Bunik, VI | 1 |
4 review(s) available for adenosine diphosphate and glutamic acid
| Article | Year |
|---|---|
From the synaptosome to the intact brain.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Brain; Cerebral Cortex; Energy Metabolism; Glutamic Acid; Guinea Pigs; Hypoxia, Brain; Magnetic Resonance Spectroscopy; Synaptosomes | 1994 |
The mechanism of lithium action: state of the art, ten years later.
Topics: 5'-Nucleotidase; Adenosine Diphosphate; Animals; Antimanic Agents; Calcium-Calmodulin-Dependent Protein Kinases; Glutamic Acid; Glycogen Synthase Kinases; Humans; Lithium; Receptors, Serotonin | 2001 |
Regulation of human glutamate dehydrogenases: implications for glutamate, ammonia and energy metabolism in brain.
Topics: Adenosine Diphosphate; Ammonia; Animals; Brain; Energy Metabolism; Glutamate Dehydrogenase; Glutamic Acid; Humans; Leucine; Protein Isoforms; Recombinant Proteins | 2001 |
[Purinergic modulation of the brain dopaminergic transmission: behavioral-pharmacologic conclusions].
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Dopamine; Dopamine Agents; Electroencephalography; Feeding Behavior; Glutamic Acid; Humans; Limbic System; Motor Activity; Nucleus Accumbens; Receptors, Purinergic P1; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Ventral Tegmental Area | 2008 |
2 trial(s) available for adenosine diphosphate and glutamic acid
| Article | Year |
|---|---|
Is glutamine beneficial in ischemic heart disease?
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Administration, Oral; Aged; Angina Pectoris; Animals; Aspartic Acid; Cardiac Output; Dose-Response Relationship, Drug; Double-Blind Method; Drug Evaluation; Exercise Test; Glutamic Acid; Glutamine; Glutathione; Heart; Humans; Male; Middle Aged; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Rats; Rats, Sprague-Dawley; Time Factors | 2002 |
Myocardial metabolic changes during pediatric cardiac surgery: a randomized study of 3 cardioplegic techniques.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Biomarkers; Cardiac Surgical Procedures; Child; Child Welfare; Child, Preschool; Combined Modality Therapy; Female; Glutamic Acid; Heart Arrest, Induced; Heart Defects, Congenital; Humans; Hypothermia, Induced; Infant; Infant Welfare; Lactic Acid; Male; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; Postoperative Complications; Potassium Compounds; Prospective Studies; Survival Analysis; Treatment Outcome; Troponin I; United Kingdom | 2004 |
174 other study(ies) available for adenosine diphosphate and glutamic acid
| Article | Year |
|---|---|
Carrier-mediated glutamate secretion by Corynebacterium glutamicum under biotin limitation.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Anions; Biological Transport; Carbon; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cations, Monovalent; Chlorides; Corynebacterium; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Membrane Potentials; Oxygen; Potassium; Protons | 1992 |
Nucleotide-iron-sulfur cluster signal transduction in the nitrogenase iron-protein: the role of Asp125.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aspartic Acid; Azotobacter vinelandii; Binding Sites; Crystallization; Electron Transport; Glutamates; Glutamic Acid; Iron-Sulfur Proteins; Molecular Structure; Mutagenesis, Site-Directed; Nitrogenase; Protein Conformation; Signal Transduction | 1992 |
Differential in vivo and in vitro effect of gentamicin on glutamate synthesis and glutamate deamination in rabbit kidney-cortex tubules and mitochondria.
Topics: Adenosine Diphosphate; Ammonia; Animals; Deamination; Gentamicins; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Kidney Cortex; Kidney Tubules; Male; Mitochondria; Rabbits; Tobramycin | 1992 |
Evaluation of cysteine 283 and glutamic acid 284 in the coenzyme binding site of Salmonella typhimurium glutamate dehydrogenase by site-directed mutagenesis and reaction with the nucleotide analogue 2-[4-bromo-2,3-dioxobutyl)thio)-1,N6-ethenoadenosine 2',
Topics: Adenosine Diphosphate; Affinity Labels; Amino Acid Sequence; Base Sequence; Binding Sites; Cysteine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Genes, Bacterial; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Salmonella typhimurium | 1991 |
Effect of corticosterone treatment on energy metabolism in rat liver mitochondria.
Topics: Adenosine Diphosphate; Aging; Animals; Ascorbic Acid; Corticosterone; Energy Metabolism; Glutamates; Glutamic Acid; Liver; Male; Mitochondria, Liver; Organ Size; Oxidative Phosphorylation; Rats; Succinates; Succinic Acid; Tetramethylphenylenediamine | 1991 |
Activity-dependent recruitment of endogenous glutamate for exocytosis.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Energy Metabolism; Exocytosis; Glutamates; Glutamic Acid; In Vitro Techniques; Kinetics; Male; Nerve Endings; Perfusion; Potassium; Rats; Rats, Inbred Strains; Recruitment, Neurophysiological; Sodium; Synaptosomes | 1991 |
Pore-like and carrier-like properties of the mitochondrial aspartate/glutamate carrier after modification by SH-reagents: evidence for a performed channel as a structural requirement of carrier-mediated transport.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Aspartic Acid; Biological Transport; Carrier Proteins; Cattle; Glutamates; Glutamic Acid; Ion Channels; Sulfhydryl Reagents | 1990 |
The mitochondrial aspartate/glutamate and ADP/ATP carrier switch from obligate counterexchange to unidirectional transport after modification by SH-reagents.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Aspartic Acid; Bacterial Outer Membrane Proteins; Biological Transport; Calcium; Carrier Proteins; Cattle; Glutamates; Glutamic Acid; In Vitro Techniques; Liposomes; Mitochondria; Porins; Sulfhydryl Reagents | 1990 |
Rat brain synaptosomes prepared by phase partition.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Brain; Calcium; Glutamates; Glutamic Acid; Histological Techniques; Male; Neurology; Oxygen Consumption; Rats; Synaptosomes | 1990 |
Dual effect of amiodarone on mitochondrial respiration. Initial protonophoric uncoupling effect followed by inhibition of the respiratory chain at the levels of complex I and complex II.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amiodarone; Animals; Dinitrophenols; Drug Synergism; Fatty Acids; Glutamates; Glutamic Acid; Malates; Male; Membrane Potentials; Mice; Mitochondria, Liver; Oligomycins; Oxygen Consumption; Protons; Stimulation, Chemical; Succinates; Succinic Acid; Tetraphenylborate | 1990 |
Uptake of glutamate in Corynebacterium glutamicum. 2. Evidence for a primary active transport system.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Biological Transport, Active; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Corynebacterium; Glutamates; Glutamic Acid; Kinetics; Membrane Potentials; Potassium; Sodium Cyanide | 1990 |
Glutamate dehydrogenase: some properties of the rat brain enzyme from different cellular compartments.
Topics: Adenosine Diphosphate; Animals; Brain; Enzyme Activation; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Neuroglia; Neurons; Rats; Rats, Inbred Strains; Synaptosomes | 1990 |
Changes in myocardial mitochondrial respiration after ligation of the coronary artery in pigs.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cell Fractionation; Coronary Disease; Coronary Vessels; Female; Glutamates; Glutamic Acid; Ligation; Male; Mitochondria, Heart; Myocardial Infarction; Oxygen Consumption; Succinates; Succinic Acid; Swine | 1990 |
Changes in mitochondrial activity caused by ammonium salts and the protective effect of carnitine.
Topics: Acetates; Adenosine Diphosphate; Ammonium Chloride; Animals; Carnitine; Glutamates; Glutamic Acid; Ketoglutaric Acids; Male; Mitochondria, Liver; Oxygen Consumption; Rats; Rats, Inbred Strains | 1989 |
Study of the 5-oxoprolinase reaction by 13C NMR.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amidohydrolases; Animals; Catalysis; Chemical Phenomena; Chemistry; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Kidney; Kinetics; Magnetic Resonance Spectroscopy; Oxygen; Oxygen Isotopes; Phosphates; Pseudomonas; Pyroglutamate Hydrolase; Pyrrolidonecarboxylic Acid; Rats | 1989 |
Pyruvate kinase isozymes from the green alga, Selenastrum minutum. II. Kinetic and regulatory properties.
Topics: Adenosine Diphosphate; Animals; Chlorophyta; Dihydroxyacetone Phosphate; Drug Interactions; Enzyme Activation; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Magnesium; Manganese; Nucleotides; Phosphates; Phosphoenolpyruvate; Potassium; Pyruvate Kinase; Rabbits; Substrate Specificity | 1989 |
Enzymic urea assay: a new colorimetric method based on hydrogen peroxide measurement.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aminopyrine; Ammonia; Colorimetry; Glutamate-Ammonia Ligase; Glutamates; Glutamic Acid; Horseradish Peroxidase; Humans; Hydrogen Peroxide; Kinetics; Pyruvate Kinase; Spectrophotometry; Urea; Urease | 1989 |
Delayed neurologic deterioration following anoxia: brain mitochondrial and metabolic correlates.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood Glucose; Brain; Carbon Dioxide; Cats; Cytochrome b Group; Female; Flavin-Adenine Dinucleotide; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Hypoxia; Lactates; Lactic Acid; Male; Mitochondria; NAD; Organ Size; Oxygen; Oxygen Consumption; Phosphocreatine; Succinates; Succinic Acid | 1989 |
Activation of glutamate by gamma-glutamate kinase: formation of gamma-cis-cycloglutamyl phosphate, an analog of gamma-glutamyl phosphate.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aldehyde Oxidoreductases; Chromatography, High Pressure Liquid; Drug Stability; Escherichia coli; Glutamate-5-Semialdehyde Dehydrogenase; Glutamates; Glutamic Acid; Hydroxamic Acids; Kinetics; Molecular Conformation; NADP; Organophosphorus Compounds; Phosphates; Phosphotransferases; Phosphotransferases (Carboxyl Group Acceptor); Pyrroles; Pyrrolidonecarboxylic Acid | 1989 |
[Functional properties of isolated kidney mitochondria of rats in food deprivation].
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Energy Metabolism; Glutamates; Glutamic Acid; Kidney; Malates; Male; Mitochondria; Oxygen Consumption; Rats; Rats, Inbred Strains; Starvation; Succinates; Succinic Acid | 1989 |
Effects of Stevia rebaudiana natural products on rat liver mitochondria.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Diterpenes; Diterpenes, Kaurane; Glucosides; Glutamates; Glutamic Acid; In Vitro Techniques; Mitochondria, Liver; Multienzyme Complexes; NADH, NADPH Oxidoreductases; Oxygen Consumption; Phosphorylation; Plant Extracts; Plants, Medicinal; Proteins; Rats; Sweetening Agents; Terpenes | 1985 |
Influence of cyclosporin A on the respiration of isolated rat kidney mitochondria.
Topics: Adenosine Diphosphate; Animals; Cyclosporins; Glutamates; Glutamic Acid; Kidney; Malates; Male; Mitochondria; Oxygen Consumption; Rats; Succinates; Succinic Acid | 1985 |
Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adenosine Diphosphate; Animals; Brain; Glutamates; Glutamic Acid; Malates; Male; Mice; Mitochondria; NAD; Neurotoxins; Oxidation-Reduction; Phosphorylation; Pyridines; Rats; Rats, Inbred Strains | 1985 |
Oxygen electrode studies with human skeletal muscle mitochondria in vitro. A re-appraisal.
Topics: Adenosine Diphosphate; Adolescent; Aged; Cell Fractionation; Glutamates; Glutamic Acid; Humans; In Vitro Techniques; Middle Aged; Mitochondria, Muscle; Muscle Proteins; Oxygen Consumption; Polarography; Pyruvates; Pyruvic Acid; Succinates; Succinic Acid; Tetramethylphenylenediamine | 1985 |
[Characteristic respiratory magnitude of isolated mitochondria of the rat kidney cortex in relation to measurement conditions].
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Animals; Energy Metabolism; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Kidney Cortex; Malates; Male; Mitochondria; Oxygen Consumption; Rats; Rats, Inbred Strains; Succinates; Succinic Acid | 1985 |
Effect of 5-amino-4-imidazolecarboxamide riboside on renal ammoniagenesis. Study with [15N]aspartate.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aminoimidazole Carboxamide; Ammonia; Animals; Aspartic Acid; Glutamates; Glutamic Acid; Imidazoles; Kidney; Lactates; Lactic Acid; Male; Models, Biological; Rats; Rats, Inbred Strains; Ribonucleosides | 1986 |
Synaptosomal bioenergetics. The role of glycolysis, pyruvate oxidation and responses to hypoglycaemia.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arsenic; Arsenites; Biological Transport; Energy Metabolism; Glutamates; Glutamic Acid; Glycolysis; Guinea Pigs; Hypoglycemia; In Vitro Techniques; Mitochondria; Oxidation-Reduction; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Synaptosomes | 1986 |
Formation of hexose 6-phosphates from lactate + pyruvate + glutamate by a cell-free system from rat liver.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cell-Free System; Cytosol; Ethanol; Gluconeogenesis; Glutamates; Glutamic Acid; Hexosephosphates; Lactates; Lactic Acid; Liver; Male; Mitochondria, Liver; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1986 |
Different effects of 2,4-dinitrophenol on rat liver mitochondrial oxidation of various substrates: succinate and glutamate vs 3-hydroxybutyrate and glycerol 3-phosphate.
Topics: 2,4-Dinitrophenol; 3-Hydroxybutyric Acid; Adenosine Diphosphate; Animals; Dinitrophenols; Female; Glutamates; Glutamic Acid; Glycerophosphates; Hydroxybutyrates; Male; Mitochondria, Liver; Oxidation-Reduction; Oxidative Phosphorylation; Rats; Rats, Inbred Strains; Succinates; Succinic Acid | 1987 |
Isolation of the glutamyl peptide labeled by the nucleotide analogue 2-(4-bromo-2,3-dioxobutylthio)-1,N(6)-ethenoadenosine 2',5'-biphosphate in the active site of NADP+-specific isocitrate dehydrogenase.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Animals; Binding Sites; Enzyme Activation; Glutamates; Glutamic Acid; Isocitrate Dehydrogenase; Peptide Fragments; Swine | 1987 |
[Oxidative and respiratory properties of isolated human kidney mitochondria].
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Culture Techniques; Energy Metabolism; Glutamates; Glutamic Acid; Humans; Kidney; Kidney Neoplasms; Malates; Mitochondria; Oxygen Consumption; Succinates; Succinic Acid | 1987 |
Changes in pyridine nucleotide levels alter oxygen consumption and extra-mitochondrial phosphates in isolated mitochondria: a 31P-NMR and NAD(P)H fluorescence study.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Fluorescent Dyes; Glutamates; Glutamic Acid; Magnetic Resonance Spectroscopy; Malates; Male; Mitochondria, Liver; NAD; NADP; Oxygen Consumption; Phosphates; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Rhodamines; Spectrometry, Fluorescence | 1987 |
Occurrence of a large Ca2+-independent release of glutamate during anoxia in isolated nerve terminals (synaptosomes).
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cell Membrane; Cerebral Cortex; Cyanides; Egtazic Acid; Energy Metabolism; Glutamates; Glutamic Acid; Hypoxia, Brain; Male; Potassium; Rats; Rats, Inbred Strains; Synaptosomes | 1988 |
Utilization of the synthetic phosphagen cyclocreatine phosphate by a simple brain model during stimulation by neuroexcitatory amino acids.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Brain; Chick Embryo; Glutamates; Glutamic Acid; Homocysteine; Imidazolidines; Kainic Acid; Magnesium; N-Methylaspartate; Phosphocreatine | 1988 |
Reaction mechanism of the reconstituted aspartate/glutamate carrier from bovine heart mitochondria.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Transport Systems, Acidic; Animals; Antiporters; Aspartic Acid; Binding, Competitive; Biological Transport; Carrier Proteins; Cattle; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Liposomes; Membrane Potentials; Mitochondria; Myocardium | 1988 |
Ca2+-dependent and Ca2+-independent glutamate release, energy status and cytosolic free Ca2+ concentration in isolated nerve terminals following metabolic inhibition: possible relevance to hypoglycaemia and anoxia.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cytosol; Energy Metabolism; Glutamates; Glutamic Acid; Guinea Pigs; Hypoglycemia; Membrane Potentials; Oxygen Consumption; Phosphocreatine; Rotenone; Synaptosomes | 1988 |
5-Oxo-L-prolinase (L-pyroglutamate hydrolase). Studies of the chemical mechanism.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amidohydrolases; Animals; Glutamates; Glutamic Acid; Kidney; Kinetics; Oxygen Isotopes; Pyroglutamate Hydrolase; Rats | 1981 |
Decline in respiratory control ratio of rat liver mitochondria in old age.
Topics: Adenosine Diphosphate; Aging; Animals; Energy Metabolism; Glutamates; Glutamic Acid; Malates; Mitochondria, Liver; Oxygen Consumption; Rats; Succinates; Succinic Acid | 1981 |
Kinetic studies to determine the mechanism of regulation of bovine liver glutamate dehydrogenase by nucleotide effectors.
Topics: Adenosine Diphosphate; Animals; Binding, Competitive; Cattle; Deuterium; Dose-Response Relationship, Drug; Enzyme Activation; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Guanosine Triphosphate; In Vitro Techniques; Kinetics; Liver; NADP | 1982 |
Effects of ischemia on metabolite concentrations in dog renal cortex.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Dogs; Female; Glutamates; Glutamic Acid; Hydroxybutyrates; Ischemia; Keto Acids; Ketoglutaric Acids; Kidney; Kidney Cortex; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Rats | 1982 |
Energy metabolism in cultured human fibroblasts during aging in vitro.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Cell Division; Cell Line; Cell Survival; Citric Acid Cycle; Female; Fibroblasts; Glucose; Glutamates; Glutamic Acid; Glycolysis; Humans; Lactates; Lactic Acid; Male; Oxygen Consumption; Progeria; Pyruvates; Pyruvic Acid; Skin | 1982 |
Ammonia formation from some amino acids by human term placental mitochondria.
Topics: Adenosine Diphosphate; Amino Acids; Ammonia; Female; Glutamates; Glutamic Acid; Glutamine; Humans; Mitochondria; Models, Biological; NAD; Placenta; Pregnancy | 1982 |
[Respiration and oxidative phosphorylation in liver mitochondria of bass (Morone labrax) and their dependence on temperature].
Topics: Adenosine Diphosphate; Animals; Fishes; Glutamates; Glutamic Acid; Mitochondria, Liver; Oxidative Phosphorylation; Oxygen Consumption; Succinates; Succinic Acid; Temperature | 1982 |
Hormonal regulation of mitochondrial function. Description of a system capable of mimicking several effects of glucagon.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Electron Transport; Glucagon; Glutamates; Glutamic Acid; Kinetics; Male; Mitochondria, Liver; Oligomycins; Osmolar Concentration; Oxidative Phosphorylation; Rats; Rats, Inbred Strains | 1983 |
Concerning the equilibrium exchange kinetics and mechanism of the sheep brain glutamine synthetase reaction.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Brain; Glutamate-Ammonia Ligase; Glutamates; Glutamic Acid; Glutamine; Kinetics; Phosphates; Sheep | 1983 |
Apparent identity of alpha-subunit of pyruvate dehydrogenase and the protein phosphorylated in the presence of glutamate in P2-fractions of rat cerebral cortex.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cerebral Cortex; Electrophoresis, Polyacrylamide Gel; Glutamates; Glutamic Acid; Mitochondria; Molecular Weight; NAD; Nerve Tissue Proteins; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Rats; Synaptosomes | 1984 |
The kinetic mechanism of ox liver glutamate dehydrogenase in the presence of the allosteric effector ADP. The oxidative deamination of L-glutamate.
Topics: Adenosine Diphosphate; Animals; Cattle; Deamination; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Kinetics; Liver; NAD; Oxidation-Reduction | 1984 |
Effects of lindane on liver mitochondrial function in the rat.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Animals; Ca(2+) Mg(2+)-ATPase; Dimethyl Sulfoxide; Glutamates; Glutamic Acid; Hexachlorocyclohexane; Kinetics; Male; Mitochondria, Liver; Oxidation-Reduction; Oxygen Consumption; Rats; Rats, Inbred Strains | 1984 |
Changes in the distribution of the control of the mitochondrial oxidative phosphorylation in regenerating rabbit liver.
Topics: Adenosine Diphosphate; Animals; Cytochromes; Enzyme Activation; Glutamic Acid; Hepatectomy; Liver Regeneration; Male; Mitochondria, Liver; Oxidative Phosphorylation; Rabbits | 1994 |
Influence of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors on mitochondrial respiration in rat liver during ischemia.
Topics: Adenosine Diphosphate; Animals; Cell Fractionation; Glutamic Acid; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ischemia; Liver; Lovastatin; Male; Mitochondria, Liver; Oxygen Consumption; Pravastatin; Rats; Rats, Sprague-Dawley; Simvastatin; Succinates | 1994 |
Influence of calcium on NADH and succinate oxidation by rat heart submitochondrial particles.
Topics: Adenosine Diphosphate; Animals; Calcium; Electron Transport; Glutamic Acid; Male; Mitochondria, Heart; NAD; Oxygen Consumption; Rats; Rats, Wistar; Submitochondrial Particles; Succinates; Succinic Acid | 1995 |
Differential effect of metabolic fuels on the energy state and Na(+)-K(+)-ATPase in isolated cerebral microvessels.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Biological Transport; Carnitine; Cattle; Cerebrovascular Circulation; Energy Metabolism; Glucose; Glutamates; Glutamic Acid; Hydroxybutyrates; In Vitro Techniques; Kinetics; Microcirculation; Muscle, Smooth, Vascular; Oleic Acid; Oleic Acids; Ouabain; Pyruvates; Pyruvic Acid; Rubidium; Sodium-Potassium-Exchanging ATPase | 1993 |
ATP- and UTP-induced currents in macrophages and macrophage polykaryons.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Cell Membrane; Cells, Cultured; Cytosol; Egtazic Acid; Electric Stimulation; Glutamates; Glutamic Acid; Macrophages, Peritoneal; Magnesium; Meglumine; Membrane Potentials; Mice; Models, Biological; Potassium Channels; Quinine; Uridine Triphosphate | 1993 |
[The effect of L-glutamic acid on the ADP-induced aggregation and Ca, Mg-ATpase activity of human thrombocytes].
Topics: Adenosine Diphosphate; Blood Donors; Blood Platelets; Ca(2+) Mg(2+)-ATPase; Depression, Chemical; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Humans; Platelet Activation; Platelet Aggregation; Time Factors | 1993 |
Regulation of the glutamate dehydrogenase activity in rat islets of Langerhans and its consequence on insulin release.
Topics: Adenosine Diphosphate; Animals; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Insulin; Islets of Langerhans; Ketoglutaric Acids; Kinetics; Leucine; Magnesium; Male; Mitochondria; Osmolar Concentration; Polyamines; Rats; Rats, Wistar; Subcellular Fractions | 1994 |
Activation of bovine liver glutamate dehydrogenase by covalent reaction of adenosine 5'-O-[S-(4-bromo-2,3-dioxobutyl)thiophosphate] with arginine-459 at an ADP regulatory site.
Topics: Adenosine Diphosphate; Affinity Labels; Allosteric Regulation; Amino Acid Sequence; Animals; Cattle; Enzyme Activation; Glutamate Dehydrogenase; Glutamic Acid; Kinetics; Ligands; Liver; Molecular Sequence Data; NAD; Peptide Fragments; Sequence Analysis; Thionucleotides | 1994 |
In vitro changes in platelet function and metabolism following increasing doses of ultraviolet-B irradiation.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Bicarbonates; Blood Platelets; Dose-Response Relationship, Radiation; Glucose; Glutamates; Glutamic Acid; Glutamine; Humans; Hydrogen-Ion Concentration; Hypoxanthine; Hypoxanthines; Lactates; Leukocyte Count; Osmosis; Platelet Count; Temperature; Ultraviolet Rays | 1993 |
Respiratory activity of isolated liver Mitochondria following Trypanosoma congolense infection in rabbits: the role of thyroxine.
Topics: Adenosine Diphosphate; Animals; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Glutamates; Glutamic Acid; Malates; Male; Mitochondria, Liver; Oxidative Phosphorylation; Oxygen Consumption; Rabbits; Thyroxine; Trypanosoma congolense; Trypanosomiasis, African | 1993 |
Adenosine triphosphate depletion reverses sodium-dependent, neuronal uptake of glutamate in rat hippocampal slices.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Transport System X-AG; Animals; Arsenites; Azides; Biological Transport; Carrier Proteins; Dinitrophenols; Egtazic Acid; Glutamate Plasma Membrane Transport Proteins; Glutamates; Glutamic Acid; Glycolysis; Hippocampus; In Vitro Techniques; Iodoacetates; Iodoacetic Acid; Kinetics; Neurons; Rats; Rats, Sprague-Dawley; Rotenone; Sodium; Symporters | 1993 |
Discovery of the ammonium substrate site on glutamine synthetase, a third cation binding site.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Binding Sites; Binding, Competitive; Cations, Monovalent; Cesium; Crystallography, X-Ray; Glutamate-Ammonia Ligase; Glutamic Acid; Kinetics; Models, Molecular; Quaternary Ammonium Compounds; Salmonella typhimurium; Thallium | 1995 |
Increase in ADP-ribosyltransferase activity of rat T lymphocyte alloantigen RT6.1 by a single amino acid mutation.
Topics: Adenosine Diphosphate; ADP Ribose Transferases; Amino Acid Sequence; Animals; Antigens, Differentiation, T-Lymphocyte; Base Sequence; DNA Primers; Glutamic Acid; Glutamine; Histocompatibility Antigens; Membrane Glycoproteins; Molecular Sequence Data; Point Mutation; Poly(ADP-ribose) Polymerases; Rats; Recombinant Fusion Proteins; T-Lymphocytes | 1996 |
Unusual pKa of the carboxylate at the putative catalytic position of the thermophilic F1-ATPase beta subunit determined by 13C-NMR.
Topics: Adenosine Diphosphate; Bacillus; Binding Sites; Carbocysteine; Carboxylic Acids; Catalysis; Glutamic Acid; Hydrogen-Ion Concentration; Iodoacetates; Iodoacetic Acid; Magnetic Resonance Spectroscopy; Mutation; Proton-Translocating ATPases; Temperature | 1996 |
Negative control of DNA replication by hydrolysis of ATP bound to DnaA protein, the initiator of chromosomal DNA replication in Escherichia coli.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Bacterial Proteins; Chromosomes, Bacterial; DNA Replication; DNA-Binding Proteins; DNA, Bacterial; Escherichia coli; Glutamic Acid; Hydrolysis; Mutagenesis, Site-Directed; Recombinant Fusion Proteins; Replication Origin | 1997 |
Arachidonic acid inhibits uptake of amino acids and potentiates PKC effects on glutamate, but not GABA, exocytosis in isolated hippocampal nerve terminals.
Topics: 4-Aminopyridine; Adenosine Diphosphate; Adenosine Triphosphate; Amino Acids; Animals; Arachidonic Acid; Aspartic Acid; Biological Transport; Exocytosis; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Indomethacin; Kinetics; L-Lactate Dehydrogenase; Male; Masoprocol; Nerve Endings; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Wistar; Sodium; Synaptosomes | 1997 |
Modulation of glutamate release from rat hippocampal synaptosomes by nitric oxide.
Topics: 4-Aminopyridine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cyclic GMP; Glutamic Acid; Hippocampus; Hydroxylamine; Male; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Synaptosomes | 1997 |
Exocytotic and nonexocytotic modes of glutamate release from cultured cerebellar granule cells during chemical ischaemia.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Anti-Bacterial Agents; Aspartic Acid; Brain Ischemia; Calcium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Cerebellum; Cytoplasm; Deoxyglucose; Dizocilpine Maleate; Exocytosis; Fluorescent Dyes; Glutamic Acid; Macrolides; Neurons; omega-Conotoxins; Peptides; Pyridinium Compounds; Quaternary Ammonium Compounds; Rats; Receptors, N-Methyl-D-Aspartate; Sodium Cyanide; Tetanus Toxin; Time Factors | 1998 |
Characterization of D10S and K71E mutants of human cytosolic hsp70.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aspartic Acid; Clathrin; Cytochrome c Group; Cytosol; Glutamic Acid; Heat-Shock Proteins; HSP40 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Humans; Lysine; Mutagenesis, Insertional; Nucleotides; Peptides; Recombinant Proteins; Serine | 1998 |
Kinetic characterization of myosin head fragments with long-lived myosin.ATP states.
Topics: Actins; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Dictyostelium; Glutamic Acid; Hydrolysis; Kinetics; Mutagenesis, Site-Directed; Myosins; ortho-Aminobenzoates; Protein Binding; Spectrometry, Fluorescence; Valine | 1998 |
Altered mitochondrial function in canine ceroid-lipofuscinosis.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Disease Models, Animal; Dogs; Glutamic Acid; Malates; Microscopy, Electron; Mitochondria, Liver; Neuronal Ceroid-Lipofuscinoses; Oxygen Consumption; Succinic Acid | 1998 |
Methylmalonate toxicity in primary neuronal cultures.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apoptosis; Aspartic Acid; Brain; Calcium; Cell Death; Cells, Cultured; Cerebral Cortex; Corpus Striatum; Electron Transport Complex II; Fetus; gamma-Aminobutyric Acid; Glutamic Acid; Kinetics; Methylmalonic Acid; Mice; Microscopy, Video; Multienzyme Complexes; Neurons; Oxidoreductases; Potassium; Rats; Rats, Sprague-Dawley; Sodium; Succinate Dehydrogenase; Time Factors | 1998 |
Mutation to the glutamate in the fourth membrane segment of Na+,K+-ATPase and Ca2+-ATPase affects cation binding from both sides of the membrane and destabilizes the occluded enzyme forms.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Binding Sites; Calcium; Calcium-Transporting ATPases; Cations; Cell Membrane; Enzyme Activation; Enzyme Stability; Glutamic Acid; Glutamine; Hydrolysis; Isoenzymes; Membrane Proteins; Mutagenesis, Site-Directed; Oligomycins; Phosphorylation; Potassium; Rats; Rubidium; Sodium-Potassium-Exchanging ATPase; Thapsigargin | 1998 |
Functional role of the N-terminal region of the Lon protease from Mycobacterium smegmatis.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acid Substitution; ATP-Dependent Proteases; Bacterial Proteins; Caseins; Enzyme Activation; Escherichia coli; Escherichia coli Proteins; Genetic Vectors; Glutamic Acid; Glycine; Heat-Shock Proteins; Hydrolysis; Mutagenesis, Site-Directed; Mycobacterium; Peptide Fragments; Promoter Regions, Genetic; Protease La; Protein Folding; Serine Endopeptidases; Serpins | 1998 |
Correction for inner filter effects in turbid samples: fluorescence assays of mitochondrial NADH.
Topics: Adenosine Diphosphate; Animals; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Fluorescent Dyes; Glutamic Acid; Least-Squares Analysis; Light; Milk; Mitochondria, Heart; NAD; Nephelometry and Turbidimetry; Scattering, Radiation; Spectrometry, Fluorescence; Swine | 1998 |
Low reserve of cytochrome c oxidase capacity in vivo in the respiratory chain of a variety of human cell types.
Topics: Adenosine Diphosphate; Carcinoma, Hepatocellular; Cell Differentiation; Cell Line; Cell Membrane Permeability; Digitonin; Electron Transport Complex IV; Glutamic Acid; Humans; Kinetics; Liver Neoplasms; Lung Neoplasms; Malates; Mitochondria; Multiple Myeloma; Neuroblastoma; Osteosarcoma; Oxygen Consumption; Potassium Cyanide; Tetramethylphenylenediamine; Tumor Cells, Cultured | 1998 |
Effect of MI-D, a new mesoionic compound, on energy-linked functions of rat liver mitochondria.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Animals; Cell Respiration; Cinnamates; Dose-Response Relationship, Drug; Electron Transport; Glutamic Acid; Male; Membrane Potentials; Mitochondria, Liver; Oxidative Phosphorylation; Oxidoreductases; Oxygen; Rats; Rats, Wistar; Succinic Acid; Thiadiazoles; Thiazoles; Uncoupling Agents | 1998 |
Neuroligand-mediated calcium signaling in cultured human schwannoma cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Bradykinin; Calcium; Cell Division; Endothelin-2; Fluorescent Dyes; Glutamic Acid; Histamine; Humans; Microscopy, Confocal; Neurilemmoma; Neurofibromatosis 2; Norepinephrine; Serotonin; Signal Transduction; Tumor Cells, Cultured | 1999 |
Characterization of P2 receptors modulating neural activity in rat rostral ventrolateral medulla.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Electric Stimulation; Glutamic Acid; Male; Medulla Oblongata; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Spinal Cord; Thionucleotides | 1999 |
Aging selectively decreases oxidative capacity in rat heart interfibrillar mitochondria.
Topics: Adenosine Diphosphate; Aging; Animals; Ascorbic Acid; Cell Respiration; Citrate (si)-Synthase; Electron Transport; Electron Transport Complex IV; Glutamic Acid; Male; Mitochondria, Heart; Myocardium; NADH Dehydrogenase; Oxidative Phosphorylation; Phosphatidylcholines; Phospholipids; Rats; Rats, Inbred F344; Sarcolemma; Succinate Cytochrome c Oxidoreductase; Uncoupling Agents | 1999 |
Dual responses of CNS mitochondria to elevated calcium.
Topics: Adenosine Diphosphate; Animals; Antineoplastic Agents; Atractyloside; Brain; Calcium; Electric Conductivity; Fluorescent Dyes; Fura-2; Glutamic Acid; Membrane Potentials; Mitochondria; Mitochondrial Swelling; Nerve Degeneration; Oligomycins; Onium Compounds; Organophosphorus Compounds; Oxidation-Reduction; Oxygen Consumption; Rats; Strontium; Succinic Acid; Uncoupling Agents | 2000 |
Effect of aluminium-induced Alzheimer like condition on oxidative energy metabolism in rat liver, brain and heart mitochondria.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Aging; Aluminum Chloride; Aluminum Compounds; Alzheimer Disease; Animals; Body Temperature; Brain; Chlorides; Disease Models, Animal; Energy Metabolism; Glutamic Acid; Male; Membrane Fluidity; Mitochondria, Heart; Mitochondria, Liver; Oxidative Phosphorylation; Rats | 1999 |
The modulation of ecto-nucleotidase activities by glutamate in cultured cerebellar granule cells.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Animals; Animals, Newborn; Cell Culture Techniques; Cerebellar Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Neurons; Rats; Rats, Wistar; Time Factors | 2000 |
Identification of an Fe protein residue (Glu146) of Azotobacter vinelandii nitrogenase that is specifically involved in FeMo cofactor insertion.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Amino Acid Substitution; Azotobacter vinelandii; Computer Simulation; Electron Spin Resonance Spectroscopy; Glutamic Acid; Iron; Kinetics; Models, Molecular; Molecular Sequence Data; Molybdoferredoxin; Mutagenesis, Site-Directed; Nitrogenase; Oxidoreductases; Protein Conformation; Sequence Alignment; Sequence Homology, Amino Acid | 2000 |
Developmental changes in mitochondrial activity and energy metabolism in fetal and neonatal rat brain.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Animals, Newborn; Brain; Energy Metabolism; Female; Glutamic Acid; Lactic Acid; Malates; Mitochondria; Pregnancy; Rats; Rats, Wistar | 2000 |
Impairment of brain mitochondrial function by hydrogen peroxide.
Topics: Adenosine Diphosphate; Animals; Brain; Cell Respiration; Deferoxamine; Dose-Response Relationship, Drug; Electron Transport Complex I; Glutamic Acid; Glutathione Disulfide; Hydrogen Peroxide; Kinetics; Malates; Male; Mitochondria; NADH Dehydrogenase; NADH, NADPH Oxidoreductases; Oxygen; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Rats; Rats, Inbred Strains; Succinic Acid; tert-Butylhydroperoxide | 2000 |
Electrogenic sodium-sodium exchange carried out by Na,K-ATPase containing the amino acid substitution Glu779Ala.
Topics: Adenosine Diphosphate; Alanine; Amino Acid Substitution; Enzyme Inhibitors; Glutamic Acid; HeLa Cells; Humans; Membrane Potentials; Ouabain; Sodium-Potassium-Exchanging ATPase | 2000 |
Purification and characterization of cytosolic pyruvate kinase from Brassica napus (rapeseed) suspension cell cultures: implications for the integration of glycolysis with nitrogen assimilation.
Topics: Adenosine Diphosphate; Allosteric Regulation; Aspartic Acid; Brassica; Cells, Cultured; Chromatography, Affinity; Chromatography, Liquid; Cytosol; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Glutamic Acid; Glycolysis; Hydrogen-Ion Concentration; Immunoblotting; Kinetics; Magnesium; Mitochondria; Models, Biological; Nitrogen; Plant Proteins; Potassium; Pyruvate Kinase; Temperature | 2000 |
Characterization of the metal binding environment of catalytic site 1 of chloroplast F1-ATPase from Chlamydomonas.
Topics: Adenosine Diphosphate; Animals; Aspartic Acid; Binding Sites; Catalysis; Chlamydomonas reinhardtii; Chloroplasts; Electron Spin Resonance Spectroscopy; Glutamic Acid; Mutagenesis, Site-Directed; Protein Conformation; Proton-Translocating ATPases; Spin Labels; Vanadates | 2000 |
Nerve tissue-specific (GLUD2) and housekeeping (GLUD1) human glutamate dehydrogenases are regulated by distinct allosteric mechanisms: implications for biologic function.
Topics: Adenosine Diphosphate; Allosteric Regulation; Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Cell Line; Dose-Response Relationship, Drug; Drug Synergism; Glutamate Dehydrogenase; Glutamic Acid; Guanosine Triphosphate; Humans; Isoenzymes; Ketoglutaric Acids; Leucine; Nerve Tissue; Oxidation-Reduction; Recombinant Proteins; Spodoptera; Transfection | 2000 |
Limitations of cyclosporin A inhibition of the permeability transition in CNS mitochondria.
Topics: Adenosine Diphosphate; Animals; Brain; Brain Chemistry; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cyclophilins; Cyclosporine; Enzyme Inhibitors; Glutamic Acid; Intracellular Membranes; Magnesium; Membrane Potentials; Mitochondria; Mitochondrial Swelling; Oligomycins; Onium Compounds; Organophosphorus Compounds; Palmitic Acid; Permeability; Polyethylene Glycols; Rats; Serum Albumin, Bovine | 2000 |
Purification and characterization of cytosolic pyruvate kinase from banana fruit.
Topics: Adenosine Diphosphate; Allosteric Regulation; Aspartic Acid; Cations; Coenzymes; Cytosol; Fruit; Glutamic Acid; Glyceric Acids; Hydrogen-Ion Concentration; Kinetics; Metals; Molecular Weight; Phosphoenolpyruvate; Phosphoenolpyruvate Carboxylase; Pyruvate Kinase; Thermodynamics; Zingiberales | 2000 |
Calcium sequestering ability of mitochondria modulates influx of calcium through glutamate receptor channel.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cerebral Cortex; Enzyme Inhibitors; Glutamic Acid; In Vitro Techniques; Intracellular Membranes; Ion Channels; Ionophores; Manganese; Membrane Potentials; Mitochondria; Oligomycins; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Rotenone; Ruthenium Red | 2000 |
Structures of bovine glutamate dehydrogenase complexes elucidate the mechanism of purine regulation.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Allosteric Regulation; Animals; Catalytic Domain; Cattle; Crystallography; Gene Expression Regulation, Enzymologic; Glutamate Dehydrogenase; Glutamic Acid; Guanosine Triphosphate; Humans; Ketoglutaric Acids; Ligands; Models, Molecular; NAD; NADP; Purines; Species Specificity | 2001 |
Persistent binding of MgADP to the E187A mutant of Escherichia coli phosphofructokinase in the absence of allosteric effects.
Topics: Adenosine Diphosphate; Alanine; Allosteric Regulation; Allosteric Site; Binding, Competitive; Cations, Divalent; Escherichia coli; Fluorescence Polarization; Fructosephosphates; Glutamic Acid; Ligands; Magnesium; Mutagenesis, Site-Directed; Phosphoenolpyruvate; Phosphofructokinase-1; Protein Binding; Spectrometry, Fluorescence | 2001 |
Kinetic mechanism and regulation of myosin VI.
Topics: Actins; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Alanine; Amino Acid Substitution; Animals; Glutamic Acid; Kinetics; Myosin Heavy Chains; Protein Binding; Pyrenes; Spectrometry, Fluorescence; Swine; Threonine | 2001 |
Receptor binding properties of di (1,N6-ethenoadenosine) 5', 5'''-P1, P4-tetraphosphate and its modulatory effect on extracellular glutamate levels in rat striatum.
Topics: Adenosine Diphosphate; Animals; Corpus Striatum; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Extracellular Space; Glutamic Acid; Hippocampus; Male; Neurotransmitter Agents; Rats; Rats, Wistar; Receptors, Purinergic P2; Thionucleotides | 2001 |
Differential expression of glutamate dehydrogenase in cultured neurons and astrocytes from mouse cerebellum and cerebral cortex.
Topics: Adenosine Diphosphate; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Cerebellum; Cerebral Cortex; Glutamate Dehydrogenase; Glutamic Acid; Guanosine Triphosphate; Kinetics; Mice; Neurons | 2001 |
Importance of Na,K-ATPase residue alpha 1-Arg544 in the segment Arg544-Asp567 for high-affinity binding of ATP, ADP, or MgATP.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alanine; Amino Acid Substitution; Animals; Arginine; Asparagine; Aspartic Acid; Binding Sites; Conserved Sequence; Cysteine; Glutamic Acid; Magnesium; Mutagenesis, Site-Directed; Peptide Fragments; Phosphorylation; Saccharomyces cerevisiae; Serine; Sodium-Potassium-Exchanging ATPase; Swine; Thermodynamics | 2002 |
Expression, purification and characterization of human glutamate dehydrogenase (GDH) allosteric regulatory mutations.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Allosteric Site; Animals; Binding Sites; Cattle; Chaperonin 10; Chaperonin 60; Crystallography, X-Ray; DNA, Complementary; Dose-Response Relationship, Drug; Escherichia coli; Glutamate Dehydrogenase; Glutamic Acid; Guanosine Triphosphate; Humans; Ketoglutaric Acids; Mitochondria; Models, Molecular; Mutagenesis, Site-Directed; Mutation | 2002 |
ATP diphosphohydrolase (NTPDase 1) in rat hippocampal slices and effect of glutamate on the enzyme activity in different phases of development.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Binding Sites; Female; Glutamic Acid; Hippocampus; Hydrolysis; In Vitro Techniques; Kinetics; Rats; Rats, Wistar | 2002 |
Mutation of an essential glutamate residue in folylpolyglutamate synthetase and activation of the enzyme by pteroate binding.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Chromatography, Thin Layer; Enzyme Activation; Escherichia coli; Glutamic Acid; Lacticaseibacillus casei; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Peptide Synthases; Pterins | 2002 |
Importance of Glu(282) in transmembrane segment M3 of the Na(+),K(+)-ATPase for control of cation interaction and conformational changes.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Catalytic Domain; Enzyme Activation; Enzyme Inhibitors; Glutamic Acid; Isoenzymes; Models, Molecular; Mutagenesis, Site-Directed; Ouabain; Phosphorylation; Potassium; Protein Structure, Tertiary; Rats; Sodium; Sodium-Potassium-Exchanging ATPase; Time Factors; Vanadates | 2002 |
Glycolysis and glutamate accumulation into synaptic vesicles. Role of glyceraldehyde phosphate dehydrogenase and 3-phosphoglycerate kinase.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Brain; Cattle; Energy Metabolism; Glutamic Acid; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycolysis; Kinetics; Phosphoglycerate Kinase; Synaptic Vesicles | 2003 |
Differential effects of glucose and glyburide on energetics and Na+ levels of betaHC9 cells: nuclear magnetic resonance spectroscopy and respirometry studies.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cell Line; Energy Metabolism; Glucose; Glutamic Acid; Glutamine; Glyburide; Islets of Langerhans; Kinetics; Magnetic Resonance Spectroscopy; Mitochondria; Oxygen Consumption; Perfusion; Phosphocreatine; Rats; Sodium; Succinic Acid | 2003 |
[Construction of recombinant E. coli with high glutathione biosynthetic activity and the biosynthetic process].
Topics: Adenosine Diphosphate; Escherichia coli; Genes, Bacterial; Glutamate-Cysteine Ligase; Glutamic Acid; Glutathione; Glutathione Synthase; Glycine; Plasmids; Toluene; Transformation, Bacterial | 2001 |
Motor domain mutation traps kinesin as a microtubule rigor complex.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alanine; Animals; Binding Sites; Cattle; Dimerization; Drosophila Proteins; Glutamic Acid; Humans; Hydrolysis; Kinesins; Kinetics; Microtubules; Molecular Motor Proteins; Mutagenesis, Site-Directed; ortho-Aminobenzoates; Protein Structure, Tertiary; Rats; Static Electricity | 2003 |
Extracellular conversion of guanine-based purines to guanosine specifically enhances astrocyte glutamate uptake.
Topics: Adenosine Diphosphate; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Guanine; Guanosine; Guanosine Monophosphate; Guanosine Triphosphate; Rats; Rats, Wistar | 2003 |
The human D2 dopamine receptor synergizes with the A2A adenosine receptor to stimulate adenylyl cyclase in PC12 cells.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenine; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenylyl Cyclases; Animals; Benzamides; Binding, Competitive; Cell Cycle; Cell Membrane; Cofilin 1; Colforsin; Cyclic AMP; Cytoskeletal Proteins; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Enzyme Activation; Gene Expression; Glutamic Acid; Humans; Membrane Potentials; Patch-Clamp Techniques; PC12 Cells; Pertussis Toxin; Phenethylamines; Phosphodiesterase Inhibitors; Phosphoproteins; Propionates; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrrolidines; Quinpirole; Radioligand Assay; Rats; Receptors, Dopamine D2; Receptors, Purinergic P1; Thionucleotides; Transfection; Triazines; Triazoles; Xenopus Proteins | 2003 |
Regulatory effects of 5'-deoxypyridoxal on glutamate dehydrogenase activity and insulin secretion in pancreatic islets.
Topics: Adenosine Diphosphate; Animals; Enzyme Activation; Glutamate Dehydrogenase; Glutamic Acid; Guanosine Diphosphate; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; L-Lactate Dehydrogenase; Pyridoxal; Rats; Rats, Sprague-Dawley | 2003 |
Role of carboxylate residues adjacent to the conserved core Walker B motifs in the catalytic cycle of multidrug resistance protein 1 (ABCC1).
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Motifs; Amino Acid Sequence; Animals; Aspartic Acid; Biological Transport; Carboxylic Acids; Catalysis; Cell Line; Cell Membrane; DNA, Complementary; Drug Resistance, Multiple; Electrophoresis, Polyacrylamide Gel; Glutamic Acid; Humans; Hydrolysis; Insecta; Leukotriene C4; Light; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Mutation; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Sequence Homology, Amino Acid; Time Factors; Vanadates | 2003 |
Effect of corticosterone treatment on mitochondrial oxidative energy metabolism in developing rat brain.
Topics: Adenosine Diphosphate; Age Factors; Animals; Brain; Corticosterone; Dose-Response Relationship, Drug; Drug Administration Schedule; Energy Metabolism; Glutamic Acid; Male; Mitochondria; Oxidation-Reduction; Oxidative Phosphorylation; Oxidoreductases; Oxygen Consumption; Rats; Rats, Inbred Strains | 2003 |
Occurrence of two different glutamate dehydrogenase activities in the halophilic bacterium Salinibacter ruber.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Bacterial Proteins; Bacteroidetes; Enzyme Activation; Enzyme Stability; Glutamate Dehydrogenase; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Ketoglutaric Acids; Leucine; NAD; NADP; Phenylalanine; Potassium Chloride; Sodium Chloride; Substrate Specificity | 2003 |
Abnormal mitochondrial respiration in skeletal muscle in patients with peripheral arterial disease.
Topics: Adenosine Diphosphate; Aged; Atractyloside; Biopsy; Enzyme Inhibitors; Female; Glutamic Acid; Humans; In Vitro Techniques; Intermittent Claudication; Ischemia; Malates; Male; Middle Aged; Mitochondria, Muscle; Mitochondrial ADP, ATP Translocases; Muscle, Skeletal; Oxygen Consumption | 2003 |
Sulfite-mediated oxidative stress in kidney cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cell Respiration; Cell Survival; Cells, Cultured; Energy Metabolism; Glutamate Dehydrogenase; Glutamic Acid; Kidney Tubules, Distal; Kidney Tubules, Proximal; Malate Dehydrogenase; Male; Membrane Potentials; Opossums; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Sulfites | 2004 |
The ionic track in the F1-ATPase from the thermophilic Bacillus PS3.
Topics: Adenosine Diphosphate; Amino Acid Substitution; Arginine; Bacillus; Bacterial Proton-Translocating ATPases; Catalytic Domain; Copper; Cysteine; Enzyme Activation; Enzyme Inhibitors; Glutamic Acid; Lysine; Methylation; Mutagenesis, Site-Directed; Protein Subunits; Sodium-Potassium-Exchanging ATPase; Temperature | 2004 |
Microtubule-kinesin interface mutants reveal a site critical for communication.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alanine; Animals; Binding Sites; Catalysis; Cell Communication; Drosophila Proteins; Glutamic Acid; Hydrolysis; Kinesins; Kinetics; Lysine; Microtubules; Molecular Motor Proteins; Mutagenesis, Site-Directed; ortho-Aminobenzoates | 2004 |
Effect of coenzyme Q10 on the mitochondrial function of skin fibroblasts from Parkinson patients.
Topics: Adenosine Diphosphate; Adult; Aged; Amobarbital; Antioxidants; Cells, Cultured; Coenzymes; Drug Interactions; Female; Fibroblasts; Glutamic Acid; Humans; Male; Middle Aged; Mitochondria; NAD; Oxygen; Parkinson Disease; Pyruvic Acid; Skin; Ubiquinone | 2004 |
Ca2+ occlusion and gating function of Glu309 in the ADP-fluoroaluminate analog of the Ca2+-ATPase phosphoenzyme intermediate.
Topics: Adenosine Diphosphate; Aluminum; Animals; Binding Sites; Calcium; Calcium Signaling; Calcium-Transporting ATPases; Chickens; COS Cells; Fluorine; Glutamic Acid; In Vitro Techniques; Ion Channel Gating; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Phosphorylation; Rabbits; Recombinant Proteins; Sarcoplasmic Reticulum | 2004 |
Combined mutation of catalytic glutamate residues in the two nucleotide binding domains of P-glycoprotein generates a conformation that binds ATP and ADP tightly.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Binding Sites; DNA Primers; Glutamic Acid; In Vitro Techniques; Kinetics; Mice; Mutagenesis, Site-Directed; Protein Conformation; Protein Structure, Tertiary; Recombinant Proteins | 2004 |
Properties of P-glycoprotein with mutations in the "catalytic carboxylate" glutamate residues.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Alanine; Animals; Aspartic Acid; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Carboxylic Acids; Catalysis; Dimerization; Dithiothreitol; Dose-Response Relationship, Drug; Glutamic Acid; Hydrolysis; Kinetics; Lipid Metabolism; Lysine; Mice; Models, Chemical; Mutation; Pichia; Protein Conformation; Protein Structure, Tertiary; Time Factors; Vanadates | 2004 |
Localization of a K+ -binding site involved in dephosphorylation of the sarcoplasmic reticulum Ca2+ -ATPase.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Amino Acid Sequence; Animals; Binding Sites; Calcium-Transporting ATPases; COS Cells; Crystallography, X-Ray; Cytoplasm; DNA, Complementary; Electrons; Glutamic Acid; Models, Molecular; Molecular Sequence Data; Muscle, Skeletal; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Potassium; Protein Conformation; Protein Structure, Tertiary; Protein Transport; Rabbits; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Time Factors | 2004 |
ATP excites interneurons and astrocytes to increase synaptic inhibition in neuronal networks.
Topics: Action Potentials; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Astrocytes; Calbindin 2; Calbindins; Calcium; Fluorescent Antibody Technique; Glutamic Acid; Hippocampus; In Vitro Techniques; Interneurons; Mice; Microscopy, Confocal; Nerve Net; Nerve Tissue Proteins; Neural Inhibition; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; S100 Calcium Binding Protein G; Synapses; Thionucleotides | 2004 |
Mitochondrial tissue specificity of substrates utilization in rat cardiac and skeletal muscles.
Topics: Adenosine Diphosphate; Animals; Carnitine; Cell Respiration; Energy Metabolism; Fatty Acids; Glutamic Acid; Glycerophosphates; Glycolysis; Kinetics; Lactic Acid; Malates; Male; Mitochondria; Muscle, Skeletal; Myocardium; Oxidation-Reduction; Oxidative Phosphorylation; Pyruvic Acid; Rats; Rats, Wistar | 2005 |
Structure of shikimate kinase from Mycobacterium tuberculosis reveals the binding of shikimic acid.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Arginine; Binding Sites; Catalysis; Chlorides; Chlorine; Cloning, Molecular; Crystallography, X-Ray; Glutamic Acid; Humans; Hydrogen Bonding; Ions; Kinetics; Magnesium; Models, Molecular; Molecular Sequence Data; Mycobacterium tuberculosis; Phosphotransferases (Alcohol Group Acceptor); Protein Binding; Protein Conformation; Protein Structure, Secondary; Shikimic Acid; Substrate Specificity; Tuberculosis | 2004 |
Compartmentation of energy metabolism in atrial myocardium of patients undergoing cardiac surgery.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Adenylate Kinase; Adult; Creatine Kinase; Cytoplasm; Dose-Response Relationship, Drug; Energy Metabolism; Female; Glutamic Acid; Heart Atria; Humans; Kinetics; Male; Microscopy, Confocal; Microscopy, Electron; Microscopy, Electron, Transmission; Middle Aged; Mitochondria; Mitochondria, Heart; Models, Biological; Muscle Fibers, Skeletal; Myocardium; Oxidative Phosphorylation; Oxygen; Oxygen Consumption; Phosphorylation; Pyruvate Kinase; Respiration; Spectrophotometry; Succinates; Thoracic Surgery; Time Factors | 2005 |
The central loop of Escherichia coli glutamine synthetase is flexible and functionally passive.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Catalysis; Disulfides; Escherichia coli; Glutamate-Ammonia Ligase; Glutamic Acid; Kinetics; Magnesium; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Protein Binding; Protein Conformation; Pyrenes; Ribose; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization; Temperature | 2005 |
Structural biology. Nature's rotary electromotors.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Bacterial Proteins; Binding Sites; Crystallography, X-Ray; Electrochemistry; Enterococcus; Fusobacteria; Glutamic Acid; Hydrogen-Ion Concentration; Models, Molecular; Molecular Motor Proteins; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Subunits; Sodium; Static Electricity | 2005 |
Excitotoxic injury to mitochondria isolated from cultured neurons.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcimycin; Calcium; Cell Death; Cell Survival; Cells, Cultured; Cerebellum; Cytoplasm; Electrons; Glutamic Acid; Ionophores; Ions; Membrane Potentials; Mitochondria; Neurons; Rats; Rats, Sprague-Dawley; Time Factors | 2005 |
Adenosine receptors co-operate with NMDA preconditioning to protect cerebellar granule cells against glutamate neurotoxicity.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Animals; Animals, Newborn; Cell Death; Cells, Cultured; Cerebellum; Cyclic AMP; Drug Antagonism; Excitatory Amino Acid Agonists; Glutamic Acid; Hydrolysis; N-Methylaspartate; Neurons; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline; Triazines; Triazoles | 2005 |
Dual presynaptic control by ATP of glutamate release via facilitatory P2X1, P2X2/3, and P2X3 and inhibitory P2Y1, P2Y2, and/or P2Y4 receptors in the rat hippocampus.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Astrocytoma; Calcium; Cell Line; Cell Line, Tumor; Glutamic Acid; Hippocampus; Kidney; Male; Potassium; Pyramidal Cells; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Presynaptic; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2X2; Receptors, Purinergic P2X3; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y2; Recombinant Fusion Proteins; RNA, Messenger; Subcellular Fractions; Suramin; Synaptosomes; Transfection; Triazines; Triazoles; Xanthines | 2005 |
Did protein kinase regulatory mechanisms evolve through elaboration of a simple structural component?
Topics: Adenosine Diphosphate; Amino Acid Motifs; Amino Acid Sequence; Animals; Binding Sites; Databases, Protein; Evolution, Molecular; Glutamic Acid; Histidine; Humans; Models, Genetic; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Monte Carlo Method; Protein Conformation; Protein Kinases; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Tryptophan; Tyrosine; Water | 2005 |
Developmental downregulation of P2X3 receptors in motoneurons of the compact formation of the nucleus ambiguus.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Age Factors; Animals; Animals, Newborn; Cell Count; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Gene Expression Regulation, Developmental; Glutamic Acid; Immunohistochemistry; In Vitro Techniques; Membrane Potentials; Motor Neurons; Nucleus Accumbens; Patch-Clamp Techniques; Phenols; Polycyclic Compounds; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2X3; Tetrodotoxin; Time Factors | 2005 |
Kinetic effects of kinesin switch I and switch II mutations.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Arginine; Brain; Cattle; Dimerization; Glutamic Acid; Hydrolysis; Kinesins; Kinetics; Microtubules; Mutation; Phosphates; Rats; Recombinant Proteins; Signal Transduction | 2005 |
Thrombin-stimulated glutamate uptake in human platelets is predominantly mediated by the glial glutamate transporter EAAT2.
Topics: Adenosine Diphosphate; Blood Platelets; Blotting, Western; Cell Separation; Cell Shape; Chromatography, Gel; Cytoplasmic Granules; Excitatory Amino Acid Transporter 2; Glutamic Acid; Humans; In Vitro Techniques; Kinetics; Neuroglia; Phosphatidylinositol 3-Kinases; Platelet Aggregation; Protein Kinase C; Sodium; Thrombin | 2005 |
The metabolism of C-glucose by neurons and astrocytes in brain subregions following focal cerebral ischemia in rats.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Astrocytes; Brain; Brain Infarction; Brain Ischemia; Carbon Radioisotopes; Cell Communication; Cell Death; Disease Models, Animal; Down-Regulation; Energy Metabolism; Glucose; Glutamic Acid; Glutamine; Infarction, Middle Cerebral Artery; Male; Neurons; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2006 |
Glu257 in GroEL is a sensor involved in coupling polypeptide substrate binding to stimulation of ATP hydrolysis.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Alanine; Amino Acid Substitution; Binding Sites; Chaperonin 60; Glutamic Acid; Hydrolysis; Kinetics; Lactalbumin; Mutation; Peptides; Protein Structure, Tertiary; Substrate Specificity | 2006 |
Alleviation of fatty acid and hypoxia-reoxygenation-induced proximal tubule deenergization by ADP/ATP carrier inhibition and glutamate.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Carrier Proteins; Dose-Response Relationship, Drug; Energy Metabolism; Fatty Acids; Female; Glutamic Acid; Hypoxia; Indicators and Reagents; Kidney Tubules, Proximal; Membrane Potential, Mitochondrial; Oleic Acid; Oxygen; Phenazines; Rabbits | 2007 |
Exercise training decreases rat heart mitochondria free radical generation but does not prevent Ca2+-induced dysfunction.
Topics: Adaptation, Physiological; Adenosine Diphosphate; Animals; Calcium; Catalase; Electron Transport Complex I; Glutamic Acid; Glutathione Peroxidase; Hydrogen Peroxide; Malates; Male; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Mitochondrial Swelling; Myocardial Reperfusion Injury; Oxidative Phosphorylation; Oxygen; Physical Endurance; Rats; Rats, Inbred F344; Reactive Oxygen Species; Rotenone; Succinic Acid; Superoxide Dismutase; Uncoupling Agents | 2007 |
High throughput screening reveals several new classes of glutamate dehydrogenase inhibitors.
Topics: Adenosine Diphosphate; Amination; Calorimetry; Drug Evaluation, Preclinical; Enzyme Inhibitors; Enzyme Stability; Glutamate Dehydrogenase; Glutamic Acid; Models, Molecular; Molecular Structure; Oxidation-Reduction; Temperature | 2007 |
P2Y1 receptor-mediated glutamate release from cultured dorsal spinal cord astrocytes.
Topics: Adenosine Diphosphate; Animals; Astrocytes; Calcium; Calcium Signaling; Cell Size; Cells, Cultured; Chloride Channels; Chromatography, High Pressure Liquid; Glutamic Acid; Microscopy, Confocal; Posterior Horn Cells; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Synaptic Transmission; Synaptic Vesicles; Thionucleotides; Water-Electrolyte Balance | 2008 |
Synaptic vesicle-bound pyruvate kinase can support vesicular glutamate uptake.
Topics: Adenosine Diphosphate; Animals; Glutamic Acid; Hexokinase; In Vitro Techniques; Intracellular Membranes; Membrane Potentials; Neurotransmitter Agents; Phosphoenolpyruvate; Protein Transport; Pyruvate Kinase; Rats; Synaptic Vesicles | 2009 |
Inhibition of ATP-induced glutamate release by MRS2179 in cultured dorsal spinal cord astrocytes.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Astrocytes; Calcium; Cells, Cultured; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Glutamic Acid; Microscopy, Confocal; Posterior Horn Cells; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Time Factors | 2008 |
Role of P2Y1 receptor in astroglia-to-neuron signaling at dorsal spinal cord.
Topics: Adenosine Diphosphate; Animals; Astrocytes; Calcium Signaling; Cell Communication; Cells, Cultured; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Extracellular Fluid; Glutamic Acid; Microscopy, Confocal; Patch-Clamp Techniques; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Synaptic Transmission; Thionucleotides | 2009 |
Axons and astrocytes release ATP and glutamate to evoke calcium signals in NG2-glia.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Animals, Newborn; Antigens; Aspartic Acid; Astrocytes; Axons; Calcium; Calcium Signaling; Cerebral Cortex; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glial Fibrillary Acidic Protein; Glutamic Acid; Green Fluorescent Proteins; In Vitro Techniques; Luminescent Proteins; Male; Mice; Mice, Transgenic; Optic Nerve; Pericytes; Physical Stimulation; Platelet Aggregation Inhibitors; Proteoglycans | 2010 |
Glu415 in the alpha-tubulins plays a key role in stabilizing the microtubule-ADP-kinesin complexes.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Animals; Biological Transport; Conserved Sequence; Cytoplasmic Streaming; Drosophila melanogaster; Genes, Insect; Glutamic Acid; Kinesins; Lipid Metabolism; Microtubules; Models, Biological; Molecular Sequence Data; Mutant Proteins; Oocytes; Protein Structure, Secondary; Structure-Activity Relationship; Time Factors; Tubulin | 2009 |
Astrocytic poly(ADP-ribose) polymerase-1 activation leads to bioenergetic depletion and inhibition of glutamate uptake capacity.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Alkylating Agents; Animals; Astrocytes; Cell Survival; Cells, Cultured; Cerebral Cortex; Coculture Techniques; Glutamic Acid; Methylnitronitrosoguanidine; Mice; Mice, Knockout; NAD; Neurons; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Time Factors | 2010 |
Substrate-specific derangements in mitochondrial metabolism and redox balance in the atrium of the type 2 diabetic human heart.
Topics: Adenosine Diphosphate; Adult; Cell Respiration; Citric Acid Cycle; Diabetes Mellitus, Type 2; Fatty Acids; Female; Glutamic Acid; Glutathione; Heart Atria; Heat-Shock Proteins; Humans; Hydrogen Peroxide; Kinetics; Male; Middle Aged; Mitochondria, Heart; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; PPAR alpha; Transcription Factors; Triglycerides | 2009 |
Extramitochondrial Ca2+ in the nanomolar range regulates glutamate-dependent oxidative phosphorylation on demand.
Topics: Adenosine Diphosphate; Animals; Calcium; Cell Respiration; Glutamic Acid; Mitochondria; Oxidative Phosphorylation; Rats; Rats, Wistar; Ruthenium Red | 2009 |
Adenosine A1 receptors and microglial cells mediate CX3CL1-induced protection of hippocampal neurons against Glu-induced death.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine Deaminase; Adenosine Diphosphate; Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Cell Death; Cell Movement; Clodronic Acid; CX3C Chemokine Receptor 1; Erythropoietin; Glutamic Acid; Green Fluorescent Proteins; Hippocampus; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Neurons; Organ Culture Techniques; Rats; Receptor, Adenosine A1; Receptors, Adenosine A2; Receptors, Chemokine; Xanthines | 2010 |
Oxygen-inducible glutamate oxaloacetate transaminase as protective switch transforming neurotoxic glutamate to metabolic fuel during acute ischemic stroke.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Aspartate Aminotransferase, Cytoplasmic; Aspartate Aminotransferases; Brain; Cell Survival; Cells, Cultured; Glutamic Acid; Hypoxia; Immunohistochemistry; In Vitro Techniques; Magnetic Resonance Imaging; Mice; Oxygen; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Stroke | 2011 |
Free fatty acids as inducers and regulators of uncoupling of oxidative phosphorylation in liver mitochondria with participation of ADP/ATP- and aspartate/glutamate-antiporter.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antiporters; Aspartic Acid; Atractyloside; Cell Respiration; Fatty Acids, Nonesterified; Glutamic Acid; Hydrophobic and Hydrophilic Interactions; Mitochondria, Liver; Oxidative Phosphorylation; Rats; Uncoupling Agents | 2011 |
ERK1/2 activation is involved in the neuroprotective action of P2Y13 and P2X7 receptors against glutamate excitotoxicity in cerebellar granule neurons.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Cell Survival; Cells, Cultured; Cerebellum; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Gene Expression Regulation; Glutamic Acid; MAP Kinase Signaling System; Neurons; Phosphorylation; Purinergic P2X Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Thionucleotides; Time Factors | 2011 |
Release of extracellular purines from plant roots and effect on ion fluxes.
Topics: Abscisic Acid; Adenosine Diphosphate; Adenosine Triphosphate; Arabidopsis; Calcium; Calcium Channels; Calcium Signaling; Glutamic Acid; Plant Roots; Stress, Physiological | 2011 |
Impaired neurotransmission in ether lipid-deficient nerve terminals.
Topics: Acetylcholine; Acyltransferases; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Brain; Calcium; Cerebellum; Chondrodysplasia Punctata, Rhizomelic; Exocytosis; Gene Expression Profiling; Glutamic Acid; Humans; Lipid Peroxidation; Malondialdehyde; Mice; Mice, Knockout; Oligonucleotide Array Sequence Analysis; Oxidative Stress; Phosphatidylethanolamines; Plasmalogens; Presynaptic Terminals; Synaptic Transmission; Synaptic Vesicles; Synaptosomes | 2012 |
Crystal structure of the VgrG1 actin cross-linking domain of the Vibrio cholerae type VI secretion system.
Topics: Actins; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Bacterial Proteins; Binding Sites; Blotting, Western; Cell Line; Crystallography, X-Ray; Glutamic Acid; Humans; Magnesium; Manganese; Models, Molecular; Mutation; Protein Binding; Protein Structure, Tertiary; Rabbits; Vibrio cholerae | 2012 |
Enhanced glutamate uptake into synaptic vesicles fueled by vesicle-generated ATP from phosphoenolpyruvate and ADP. Proposed role of a novel enzyme.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Chromatography, High Pressure Liquid; Glutamic Acid; Male; Phosphoenolpyruvate; Rats; Synaptic Vesicles | 2012 |
Disruption of mitochondrial homeostasis by phytanic acid in cerebellum of young rats.
Topics: Adenosine Diphosphate; Animals; Cerebellum; Dose-Response Relationship, Drug; Glutamic Acid; Homeostasis; Ketoglutaric Acids; Membrane Potential, Mitochondrial; Mitochondria; NADP; Oxygen Consumption; Phytanic Acid; Rats; Rats, Wistar; Statistics, Nonparametric | 2013 |
Insulin prevents mitochondrial generation of H₂O₂ in rat brain.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Brain; Cerebral Cortex; Dose-Response Relationship, Drug; Electron Transport; Embryo, Mammalian; Gene Expression Regulation; Glutamic Acid; Hydrogen Peroxide; Insulin; Male; Membrane Potential, Mitochondrial; Mitochondria; Neurons; Oxidants; Oxygen Consumption; Rats; Rats, Wistar; Reactive Oxygen Species; Synaptosomes; Time Factors | 2013 |
[Pharmacological correction of experimental mitochondrial dysfunction of brain stem neurons by rhytmocor and mildronate].
Topics: Adenosine Diphosphate; Animals; Electron Transport Complex I; Glutamic Acid; Injections, Subcutaneous; Malates; Male; Methylhydrazines; Mitochondria; NAD; Neurons; Oxidation-Reduction; Oxidative Phosphorylation; Propafenone; Rats; Rats, Wistar; Rotenone; Succinic Acid | 2013 |
Disruption of endogenous purinergic signaling inhibits vascular endothelial growth factor- and glutamate-induced osmotic volume regulation of Müller glial cells in knockout mice.
Topics: Adenosine Diphosphate; Animals; Calcium Signaling; Enzyme Inhibitors; Ependymoglial Cells; Glutamic Acid; Inositol 1,4,5-Trisphosphate Receptors; Mice; Mice, Knockout; Models, Animal; Neuroglia; Osmotic Pressure; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y1; Signal Transduction; Vascular Endothelial Growth Factors; Xanthines | 2013 |
Enzymatic activity of CaMKII is not required for its interaction with the glutamate receptor subunit GluN2B.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cells, Cultured; Female; Glutamic Acid; HEK293 Cells; Humans; Male; Neurons; Phosphorylation; Protein Binding; Protein Subunits; Protein Transport; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Staurosporine; Synapses | 2013 |
[Influence of adenosine diphosphate on respiration of rat pancreatic acinar cells mitochondria in situ].
Topics: Acinar Cells; Adenosine Diphosphate; Animals; Calcium; Cell Fractionation; Digitonin; Glutamic Acid; Malates; Male; Mitochondria; Oligomycins; Oxidative Phosphorylation; Oxygen; Pancreas; Permeability; Pyruvic Acid; Rats | 2013 |
Molecular basis of nucleotide-dependent substrate engagement and remodeling by an AAA+ activator.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; DNA; Escherichia coli Proteins; Glutamic Acid; Models, Molecular; Mutation; Trans-Activators; Transcription, Genetic | 2014 |
Enteral supplements of a carbon monoxide donor CORM-A1 protect against cerebrovascular dysfunction caused by neonatal seizures.
Topics: Adenosine Diphosphate; Animals; Arterioles; Boranes; Bradykinin; Carbon Monoxide; Carbonates; Cerebrovascular Circulation; Cerebrovascular Disorders; Dietary Supplements; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Heme; Male; Quisqualic Acid; Seizures; Swine; Time Factors; Vasodilator Agents | 2015 |
Enzymatic conversion of ATP to adenosine contributes to ATP-induced inhibition of glutamate release in rat medullary dorsal horn neurons.
Topics: Action Potentials; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Male; Patch-Clamp Techniques; Posterior Horn Cells; Purinergic P2X Receptor Agonists; Purinergic P2X Receptor Antagonists; Rats; Rats, Sprague-Dawley | 2015 |
Different danger signals differently impact on microglial proliferation through alterations of ATP release and extracellular metabolism.
Topics: 5'-Nucleotidase; Adenosine; Adenosine A2 Receptor Antagonists; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Apyrase; Cell Line; Cell Proliferation; Cells, Cultured; Enzyme Inhibitors; Extracellular Space; Glutamic Acid; Lipopolysaccharides; Mice, Inbred C57BL; Microglia; Pyrimidines; Receptors, Adenosine A2; Triazoles | 2015 |
Apparent Km of mitochondria for oxygen computed from Vmax measured in permeabilized muscle fibers is lower in water enriched in oxygen by electrolysis than injection.
Topics: Adenosine Diphosphate; Animals; Electrolysis; Glutamic Acid; Malates; Male; Mitochondria; Muscle, Skeletal; Oxygen; Rats; Rats, Wistar; Saponins; Water | 2015 |
2-Methylcitric acid impairs glutamate metabolism and induces permeability transition in brain mitochondria.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Metabolism, Inborn Errors; Animals; Brain; Calcium; Citrates; Cyclosporine; Energy Metabolism; Glutamate Dehydrogenase; Glutamic Acid; Humans; Ketoglutaric Acids; Malates; Male; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Oxidative Phosphorylation; Oxygen Consumption; Propionic Acidemia; Pyruvic Acid; Rats; Rats, Wistar | 2016 |
Identification of a Novel Activator of Mammalian Glutamate Dehydrogenase.
Topics: Adenosine Diphosphate; Allosteric Regulation; Amino Acids, Cyclic; Animals; Binding, Competitive; Biocatalysis; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Activators; Glutamate Dehydrogenase; Glutamic Acid; Guanosine Triphosphate; Humans; Kinetics; Models, Molecular; NAD; Protein Binding; Protein Domains; Pyrimidines; Spectrometry, Fluorescence; Sulfonamides | 2016 |
Cyclophilin D Promotes Brain Mitochondrial F1FO ATP Synthase Dysfunction in Aging Mice.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Aging; Animals; Brain; Carrier Proteins; Cyclophilins; Gene Expression Regulation; Glutamic Acid; Immunoprecipitation; Membrane Proteins; Mice; Mice, Transgenic; Mitochondria; Mitochondrial Proton-Translocating ATPases; Oxygen Consumption; Peptidyl-Prolyl Isomerase F | 2017 |
Neurovascular uncoupling in the triple transgenic model of Alzheimer's disease: Impaired cerebral blood flow response to neuronal-derived nitric oxide signaling.
Topics: Adenosine Diphosphate; Age Factors; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Body Weight; Cerebrovascular Circulation; Disease Models, Animal; Excitatory Amino Acid Agonists; Glutamic Acid; Humans; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Neurovascular Coupling; Nitric Oxide; Nitric Oxide Synthase Type I; Presenilin-1; Signal Transduction; tau Proteins | 2017 |
The Conserved Lysine-265 Allosterically Modulates Nucleotide- and Actin-binding Site Coupling in Myosin-2.
Topics: Actins; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Alanine; Allosteric Regulation; Binding Sites; Enzyme Activation; Gene Expression; Glutamic Acid; Kinetics; Lysine; Models, Molecular; Mutation; Myosin Type II; Nucleotides; Protein Binding; Structure-Activity Relationship | 2017 |
Changes in the Subpopulation Composition and Phagocytic Activity of Monocytes in Patients with Kidney Cancer under the Influence of Metabolites In Vitro.
Topics: Adenosine Diphosphate; Adult; Biomarkers; Case-Control Studies; Cell Count; Female; Flow Cytometry; Gene Expression; Glutamic Acid; GPI-Linked Proteins; Humans; Immunophenotyping; Kidney Neoplasms; Lactic Acid; Lipopolysaccharide Receptors; Male; Middle Aged; Monocytes; Phagocytosis; Primary Cell Culture; Receptors, IgG; Tumor Microenvironment | 2021 |
Disruption of mitochondrial functions involving mitochondrial permeability transition pore opening caused by maleic acid in rat kidney.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cyclosporine; Glutamic Acid; HEK293 Cells; Humans; Kidney; Kidney Failure, Chronic; Malates; Maleates; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; NAD; Permeability; Propidium; Propionic Acidemia; Rats; Rats, Wistar | 2022 |
Structural Basis for the Binding of Allosteric Activators Leucine and ADP to Mammalian Glutamate Dehydrogenase.
Topics: Adenosine Diphosphate; Allosteric Regulation; Animals; Carbon; Cattle; Glutamate Dehydrogenase; Glutamic Acid; Leucine; Mammals; Nitrogen; Potassium | 2022 |