adenosine diphosphate has been researched along with fibrinogen in 683 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 337 (49.34) | 18.7374 |
| 1990's | 172 (25.18) | 18.2507 |
| 2000's | 115 (16.84) | 29.6817 |
| 2010's | 48 (7.03) | 24.3611 |
| 2020's | 11 (1.61) | 2.80 |
| Authors | Studies |
|---|---|
| Ballard, HS; Marcus, AJ | 1 |
| Kinlough-Rathbone, RL; Mustard, JF; Packham, MA; Perry, DW | 1 |
| Kubisz, P; Suranová, J | 4 |
| Holan, J; Kubisz, P; Stránska, M; Suranová, J | 1 |
| Kinlough-Rathbone, RL; Mustard, JF; Packham, MA; Perry, DW; Regoeczi, E | 1 |
| Ingeberg, S; Stoffersen, E | 1 |
| Greenberg, JP; Guccione, MA; Harfenist, EJ; Kinlough-Rathbone, RL; Mustard, JF; Orr, JL; Packham, MA; Perry, DW | 1 |
| Buczko, W; de Gaetano, G; Donati, MB; Franco, R | 1 |
| Gaffney, PJ; Holt, JC; Mahmoud, M | 1 |
| Hockaday, TD | 1 |
| Bang, NU; Hansen, MS | 1 |
| Henderson, RF; Henderson, TR; York, JL | 1 |
| Niewiarowski, S; Stewart, GJ | 1 |
| Coller, BS; Frank, RN; Gralnick, HR; Milton, RC | 1 |
| Smith, C; Ts'ao, CH | 1 |
| Bouma, BN; Fenton, JW; Koutts, J; Plow, EF; Walsh, PN; Zimmerman, TS | 1 |
| Haslam, RJ; Lynham, JA | 1 |
| Alfano, G; Bizzi, B; Boni, P; Leone, G | 1 |
| Coppola, L; Misso, L; Tirelli, A | 1 |
| Edgington, TS; Marguerie, GA; Plow, EF | 2 |
| Blombäck, M; Eriksson, AW; Lehmann, W; Nyman, D | 1 |
| Harfenist, EJ; Kinlough-Rathbone, RL; Mustard, JF; Packham, MA; Pai, KR; Perry, DW | 1 |
| Baumgartner, HR; Chernoff, A; Goodman, DS; Kaplan, KL; Lages, BA; Nossel, HL; Weiss, HJ; Witte, LD | 1 |
| Bennett, JS; Vilaire, G | 1 |
| Blanke, D; Fees, K; Lehnard, G; Riester, P; Schulze, B | 1 |
| Bertrand, O; Samama, M; Soria, C; Soria, J | 1 |
| Coller, BS | 3 |
| Cazenave, JP; Hirsh, J; Kinlough-Rathbone, RL; Mustard, JF; Packham, MA; Reimers, HJ; Senyi, AF | 1 |
| McPherson, J; Zucker, MB | 1 |
| Boisseau, M; Bouloumie, J; Bricaud, H; Broustet, JP; Emeriau, JP | 1 |
| Economopoulos, TC; Papayannis, AG; Stathakis, NE; Thomopoulos, D | 1 |
| Ahandrik, S; Futrakul, P; Mitrakul, C; Poshyachinda, M; Sangkawibha, N | 1 |
| Hornstra, G | 1 |
| Michaeli, D; Orloff, KG | 1 |
| Evans, PM; Jones, BM | 1 |
| Ingerman, CM; Silver, MJ; Smith, JB | 1 |
| Lough, J; Moore, S | 1 |
| De Marco, L; Fabris, F; Girolami, A; Peruffo, R; Virgolini, L | 1 |
| Barden, TP; Glueck, HI | 1 |
| Arrington, PJ; McNamara, JJ | 1 |
| Hershgold, EJ; Hood, AG; Ward, BD | 1 |
| Bachmann, F; Gilson, JR; McKenna, R; Weinberg, M; Whittaker, B | 1 |
| Goodner, CJ; Harker, LA; Koerker, DJ | 1 |
| Forsham, PH; Gerich, JE; Lorenzi, M; Mielke, CH; Rodvien, R; Tsalikian, E | 1 |
| Holm, T; Prydz, H | 1 |
| Davey, DA; Jacobs, P; Ogilvie, M; Sher, G | 1 |
| Vaisrub, S | 1 |
| Holmsen, H; Lindberg, ME; Ostvold, AC; Solum, NO | 1 |
| Cohen, I; Glaser, T; Seligsohn, U | 1 |
| Suzuki, K | 1 |
| Hadnagy, C; Jaklovszky, A | 1 |
| Cattaneo, M; Lecchi, A; Mannucci, PM; McGregor, JL; Randi, AM | 1 |
| Akkerman, JW; Burgers, JA | 1 |
| Castillo, R; Diaz-Ricart, M; Escolar, G; Garrido, M; Maragall, S; Nurden, AT; Ordinas, A; Reverter, JC; Sanz, C; Villamor, N | 1 |
| Festin, R; Larsson, A; Lindahl, TL | 1 |
| Feuerstein, G; Lynch, KM; Ohlstein, EH; Poyser, R; Rabinovici, R; Sellers, TS; Slivjak, MJ; Smith, EF; Sulpizio, A; Yue, TL | 1 |
| Colman, RF; Colman, RW; Figures, WR; Scearce, LM | 1 |
| Fukuroi, T; Kido, H; Kokawa, T; Nagata, H; Nomura, S; Soga, T; Suzuki, M; Yamaguchi, K; Yanabu, M; Yasunaga, K | 1 |
| Duggan, ME; Egbertson, MS; Halczenko, W; Hartman, GD; Laswell, WL; Lynch, RJ; Manno, PD; Naylor, AM; Smith, RL; Zhang, G | 1 |
| Ekholm, J; Hanahan, DJ; Nouchi, T; Tatsumi, Y | 1 |
| Frojmovic, M; Hantgan, RR; Hensler, ME; Lewis, JC; Taylor, RG | 1 |
| Cazenave, JP; Gachet, C; Lanza, F; Stierlé, A | 1 |
| Barnett, DB; Cahill, M; Chapman, C; Mistry, R; Wood, JK | 1 |
| Kinlough-Rathbone, RL; Perry, DW; Winocour, PD | 1 |
| Peerschke, EI | 7 |
| Boudreaux, MK; Jeffers, C; Lipscomb, D; Spano, JS | 1 |
| Heemskerk, JW; Hoyland, J; Mason, WT; Sage, SO | 1 |
| Amrani, DL; Kirschbaum, NE; Mosesson, MW | 1 |
| Cohen, L; Retzinger, GS | 1 |
| Cattaneo, M; Kinlough-Rathbone, RL; Mustard, JF; Packham, MA; Perry, DW | 1 |
| Bellucci, S; Bouillot, C; Cox, A; Hardisty, R; Heilmann, E; Hourdillé, P; Legrand, C; Nokes, T; Pannocchia, A; Pidard, D | 1 |
| Huang, TF; Sheu, JR; Teng, CM | 2 |
| Cierniewski, C; Krajewski, T; Nowak, P; Pietrucha, T | 1 |
| Andrieux, A; Gulino, D; Marguerie, G; Rabiet, MJ; Ryckewaert, JJ | 1 |
| Gartner, TK; Taylor, DB | 1 |
| Goodall, AH | 1 |
| Duarte, AM; Escribano, CG; Lucio, FJ; Marques, LD; Puyol, MR | 1 |
| Anishchuk, MG; Belitser, NV; Gorkun, OV; Pozdniakova, TM; Smekhova, TR; Veklich, VI | 1 |
| Akkerman, JW; van Willigen, G | 1 |
| Huang, TF; Liu, CZ; Ouyang, CH; Teng, CM | 1 |
| Crane, S; Johnstone, IB; Viel, L; Whiting, T | 1 |
| Kosugi, T; Minei, S; Nakamura, M; Noguchi, S; Saitoh, S; Shimoji, T | 1 |
| DeCenzo, MT; Kang, J; Saitoh, M; Slayter, HS; Smith, M; Ware, JA; Watkins, SC | 1 |
| Bozarth, JM; Chiu, AT; Mousa, SA; Pease, LJ; Reilly, TM; Roscoe, WA; Smith, RD; Timmermans, PB | 1 |
| Marguerie, G; Maurel, A; Ryckewaert, JJ | 1 |
| Ruggeri, ZM; Savage, B | 1 |
| Huang, TF; Ouyang, C; Teng, CM; Wang, WJ | 1 |
| Bizzi, B; De Candia, E; De Cristofaro, R; Landolfi, R; Rocca, B | 1 |
| Li, XL; Steiner, M | 1 |
| Barradas, MA; Dandona, P; Mathur, S; Mikhailidis, DP | 1 |
| Canciani, MT; Cattaneo, M; Kinlough-Rathbone, RL; Lecchi, A; Mannucci, PM; Mustard, JF; Packham, MA | 1 |
| Kinlough-Rathbone, RL; Mustard, JF; Packham, MA; Vickers, JD | 1 |
| George, D; Loscalzo, J; Mendelsohn, ME; O'Neill, S | 1 |
| Caen, J; Fiat, AM; Hermant, L; Jollès, P; Lévy-Toledano, S; Lu, H; Mazoyer, E; Rendu, F | 1 |
| Adelman, B; Gennings, C; Hanners, E; Strony, J | 1 |
| Anischuk, MG; Belitser, NV; Gorkun, OV; Medved, LV; Pozdnyakova, TM | 1 |
| Hardisty, RM; Powling, MJ; Warkentin, TE | 1 |
| Miyazaki, H; Sudo, T; Suzuki, T; Tamura, S | 1 |
| Abrams, CS; Budzynski, AZ; Ellison, N; Shattil, SJ | 1 |
| Kinlough-Rathbone, RL; Mustard, JF; Packham, MA; Suzuki, H; Tanoue, K; Yamazaki, H | 2 |
| Bouloux, C; Cazenave, JP; Gachet, C; Lanza, F; Maffrand, JP; Ohlmann, P; Stierlé, A | 1 |
| Hayasaki, Y; Honma, Y; Kakushi, H; Kawasumi, K; Matsubara, T; Shike, T; Takeuchi, Y; Uchida, K | 1 |
| Doellgast, GJ; Hantgan, RR; Ramsamooj, P | 1 |
| Hodson, E; Kunicki, TJ; Lombardo, VT; Roberts, JR; Ruggeri, ZM; Zimmerman, TS | 1 |
| Hatanaka, K; Kitamura, Y; Minamiyama, M; Taguchi, T; Tajima, S; Tanaka, K; Yamamoto, A | 1 |
| Coller, BS; Nurden, AT; Peerschke, EI; Rosa, JP; Scudder, LE; Seligsohn, U | 1 |
| Aranda, E; Habash, J; Irarrázabal, MJ; Lema, G; Mezzano, D; Pereira, J; Urzúa, J | 1 |
| Loscalzo, J; Vaughan, DE | 1 |
| Frelinger, AL; Ginsberg, MH; Lam, SC; Loftus, JC; Plow, EF; Smith, MA | 1 |
| Prosdocimi, M; Zatta, A | 1 |
| Budzynski, A; Scrutton, MC; Shattil, SJ | 1 |
| Bradford, H; Colman, RF; Colman, RW; Hu, CJ; Puri, RN; Zhou, FX | 1 |
| Bizzi, B; Castagnola, M; De Candia, E; De Cristofaro, R; Di Cera, E; Landolfi, R | 1 |
| Belloc, F; Hasitz, M; Hourdillé, P; Nurden, AT | 1 |
| Herd, C; Morley, J; Sanjar, S; Smith, D | 1 |
| Lawing, WJ; Santoro, SA | 1 |
| Kitajima, H; Takayama, S; Yasunaga, K | 1 |
| Bednarek, MA; Hawiger, J; Kloczewiak, M; Timmons, S | 1 |
| Kinlough-Rathbone, RL; Mustard, JF; Packham, MA; Suzuki, H; Yamazaki, H | 1 |
| Jackson, CW; Jennings, LK | 2 |
| Kinlough-Rathbone, RL; Mustard, JF; Vickers, JD | 1 |
| Arita, H; Nakano, T; Terawaki, A | 1 |
| Hawiger, J | 1 |
| Hantgan, RR | 2 |
| Guccione, MA; Livne, A; Mustard, JF; Packham, MA | 1 |
| Amrani, DL; Meh, D; Mosesson, MW; Newman, PJ | 1 |
| Kireeva, EG; Luk'ianenko, EF; Strukova, SM | 1 |
| Forbes, CD; Lowe, GD | 1 |
| Horrobin, DF; Manku, MS; Takahashi, R | 1 |
| Ando, B; Sims, PJ; Wiedmer, T | 1 |
| Bauer, AS; Brochier, J; Catimel, B; Clemetson, KJ; Dechavanne, M; McGregor, JL; McGregor, L | 1 |
| De Lara, J; Latour, JG; Léger-Gauthier, C; Théroux, P | 1 |
| Cerbone, AM; DiMinno, G; Mancini, M; Riccardi, G; Rivellese, A; Silver, MJ; Thiagarajan, P | 1 |
| Green, RA; Greene, RT; Kabel, AL; Russo, EA | 1 |
| Bennett, JS; Gartner, TK | 1 |
| Kinlough-Rathbone, RL; Lalau Keraly, C; Mustard, JF | 1 |
| Aznar, J; Regañón, E; Vila, V | 1 |
| Legrand, C; Nurden, AT | 1 |
| De Marco, L; Girolami, A; Ruggeri, ZM; Zimmerman, TS | 1 |
| Brosstad, F; Solum, NO; Stormorken, H; Thorsen, LI | 1 |
| Colman, RW | 1 |
| Moncada, S; Whittle, BJ | 1 |
| Ginsberg, MH; Marguerie, GA; Plow, EF | 2 |
| Mauss, EA; Zucker, MB | 1 |
| Houghten, RA; Ruggeri, ZM; Russell, SR; Zimmerman, TS | 1 |
| Kupinski, JM; Miller, JL | 1 |
| Cerbone, A; Cianciaruso, B; Cortese, A; Di Minno, G; Farace, MJ; Martinez, J; Murphy, S; Usberti, M | 1 |
| Hatzfeld, A; Hatzfeld, J; Levesque, JP | 1 |
| Doers, MP; Kunicki, TJ; McEver, RP; Newman, PJ | 1 |
| Inada, Y; Kasahara, K; Saito, Y; Sekiya, F; Takagi, J | 1 |
| Ginsberg, MH; Marguerie, G; Pierschbacher, MD; Plow, EF; Ruoslahti, E | 1 |
| Niewiarowski, S | 1 |
| Gralnick, H; Williams, S | 1 |
| Bhardwaj, R; Hussaini, I; Moore, PK | 1 |
| Caen, J; Corvazier, E; Maclouf, J; Pintigny, D; Wautier, JL; Wautier, MP | 1 |
| Bowie, EJ; Daniels, TM; Fass, DN; White, JG | 1 |
| Akkerman, JW; Kloprogge, E | 1 |
| Bevilacqua, C; Cattaneo, M; Kinlough-Rathbone, RL; Lecchi, A; Mustard, JF; Packham, MA | 1 |
| Mills, J; Sullam, PM; Valone, FH | 1 |
| Herold, M; Kogelnig, R; Kunz, F; Zwierzina, WD | 1 |
| Basdevant, A; Bertrand, O; Mirshahi, M; Soria, C; Soria, J | 1 |
| Hillbom, M; Neiman, J | 1 |
| Greenberg, JP; Guccione, MA; Harfenist, EJ; Kinlough-Rathbone, RL; Mustard, JF; Packham, MA; Perry, DW; Rand, ML | 1 |
| Peerschke, EI; Wainer, JA | 1 |
| Edel, J; Kaspareit, J; Messow, C | 1 |
| Jungi, TW; Kuhnert, P; Peterhans, E; Trezzini, C | 1 |
| Adelman, B; Hanners, E; Rizk, A | 1 |
| Castagnola, M; De Candia, E; De Cristofaro, R; Di Cera, E; Landolfi, R; Wyman, J | 1 |
| Canciani, MT; Cattaneo, M; Lecchi, A; Mannuci, PM; Randi, AM | 1 |
| Des Prez, RM; Gates, C; King, LE; Rees, RS; Timmons, S | 1 |
| Ando, B; Hamilton, KK; Sims, PJ; Wiedmer, T | 1 |
| Abgrall, JF; Caen, JP; Dosquet, C; Fiat, AM; Jolles, P; Raha, S | 1 |
| Cunningham, M; Hoxie, JA; Shattil, SJ | 1 |
| Joseph, G; Sharma, CP | 1 |
| Harfenist, EJ; Mustard, JF; Packham, MA | 6 |
| Chap, H; Defreyn, G; Douste-Blazy, L; Feliste, R; Maffrand, JP; Simon, MF | 1 |
| Balduini, C; Balduini, CL; Bertolino, G; Bisio, A; Sinigaglia, F; Torti, M | 1 |
| Bennett, JS; Gartner, TK; Power, JW; Shattil, SJ | 1 |
| Hawiger, J; Timmons, S | 1 |
| Cattaneo, M; Harfenist, EJ; Kinlough-Rathbone, RL; Mustard, JF; Packham, MA | 1 |
| Furui, H; Sotobata, I; Taniguchi, N; Yamauchi, K | 1 |
| Bainton, DF; Isenberg, WM; McEver, RP; Phillips, DR; Shuman, MA | 1 |
| Cerbone, AM; Di Minno, G; Iride, C; Mancini, M; Mattioli, PL; Postiglione, A | 1 |
| Boden, G; Capitanio, AM; Hershock, D; Kornecki, E; Lukasiewicz, H; Niewiarowski, S; Rawala, R | 1 |
| Bertrand, O; Denninger, MH; Elion, J; Guillin, MC; Homandberg, GA; Jandrot-Perrus, M; Mosesson, MW | 1 |
| Blanco, A; de Tezanos Pinto, M; Dupont, J; Fernández, J; Lazzari, M; Maugeri, N; Meschengieser, S | 1 |
| Abecassis, J; Beretz, A; Cazenave, JP; Eber, M; Fricker, JP; Klein-Soyer, C; Millon-Collard, R; Muller, D; Nicora, F | 1 |
| Holt, JC; Huang, TF; Lukasiewicz, H; Niewiarowski, S | 1 |
| Brosstad, F; Holm, B; Solum, NO; Thorsen, LI | 1 |
| Hawiger, J; Kloczewiak, M; Lindon, JN; McManama, G; Merrill, EW; Salzman, EW; Smith, MA; Ware, JA | 1 |
| Caen, JP; Dunn, FW; Fiat, AM; Gillessen, D; Jollès, P; Lévy-Toledano, S; Soria, C; Thomaidis, A | 1 |
| Bengmark, S; Jörgensen, C; Zoucas, E | 1 |
| Altieri, DC; Capitanio, AM; Mannucci, PM | 1 |
| Grabarek, J; Hawiger, J; Kloczewiak, M; Timmons, S | 1 |
| Dorfman, D; Ferziger, R; Karpatkin, S | 1 |
| Altieri, DC; Mannucci, PM | 1 |
| Brosstad, F; Gogstad, G; Sletten, K; Solum, NO; Thorsen, LI | 1 |
| Bellido, D | 1 |
| Bykowska, K; Kaczanowska, J; Karpowicz, M; Kopeć, M; Lopaciuk, S | 1 |
| Borg, JY; Caen, JP; Fessard, C; Mirshahi, M; Piguet, H; Soria, C; Soria, J; Tron, P | 1 |
| Gordon, JL | 1 |
| Haines, AP; Meade, TW; Miller, GJ; Stirling, Y; Thompson, SG; Vickers, MV | 1 |
| Ma, YH; Ouyang, CH; Teng, CM | 1 |
| Francis, CW; Marder, VJ; Peerschke, EI | 1 |
| Dubernard, V; Legrand, C; Nurden, AT | 1 |
| Harfenist, EJ; Mustard, JF; Packham, MA; Wrana, JL | 1 |
| Agam, G; Livne, A; Shohat, O | 2 |
| Caen, JP; Karniguian, A; Legrand, C; Legrand, YJ; Pintigny, D | 1 |
| Meade, TW; Seghatchian, MJ; Thompson, SG; Vickers, MV | 1 |
| Amrani, DL; Kunicki, TJ; Mosesson, MW; Newman, PJ | 1 |
| Edelmann, L; Haurand, M; Miyashita, C; Morgenstern, E; Reimers, HJ | 1 |
| Lüscher, EF | 2 |
| De Gaetano, G; Vermylen, J | 1 |
| Besson, P; Caen, J; Levy-Toledano, S; Rendu, F | 1 |
| Bang, NU; Csiscko, BM; Heidenreich, RO; Schroeder, JE; Trygstad, W | 1 |
| Dreyfuss, F; Kalef, M; Soferman, N; Zahavi, J | 1 |
| Andrae, ML; Nilsson, BE; Tangen, O | 1 |
| Dreyfus, MD; Jenkins, CS; Larrieu, MJ; Meyer, D | 1 |
| Connell, G; Davies, JA; Davies, T; Lederer, DA; McNicol, GP | 1 |
| Kubisz, P | 1 |
| Onel, D; Ulutin, ON; Ulutin, SB | 1 |
| Kubiaz, P; Suranová, J | 1 |
| Lüscher, EF; Massini, P; Pfueller, SL | 1 |
| Görög, P; Kovács, IB | 1 |
| Braude, AI; Davis, CE; Robbins, RS; Weller, RD | 1 |
| Karpatkin, S; Lackner, H; Regan, MG | 1 |
| Kartalis, G; Koratzis, J; Sinakos, Z; Valtis, D; Zamboulis, C | 1 |
| Born, GV | 1 |
| de Gaetano, G; Donati, MB; Vermylen, J; Verstraete, M | 1 |
| De Gaetano, G; Donati, MB; Vermylen, J | 2 |
| Caen, JP; Francou, C; Jeanneau, C; Rendu, F | 1 |
| Culasso, DE; de Gaetano, G; Donati, MB; Vermylen, J; Verstraete, M | 1 |
| Chap, H; Douste-Blazy, L; Lloveras, J | 1 |
| Ardlie, NG; Mustard, JF; Packham, MA; Perry, DW | 1 |
| Mester, L; Samama, M; Soria, C; Soria, J | 1 |
| Barthel, W; Glusa, E; Markwardt, F | 1 |
| Lloyd, JV; Mustard, JF; Nishizawa, EE | 1 |
| Holm, T; Osterud, B; Prydz, H | 1 |
| Lewis, JH | 1 |
| Pavlishchuk, SA; Petrova, TR | 1 |
| Lüscher, EF; Massini, P; Metcalf, LC; Näf, U | 1 |
| Brown, CH; Glover, CJ; Hellums, JD; Leverett, LB; McIntire, LV; Natelson, EA | 1 |
| Kirby, RE; Lassman, HB; Novick, WJ | 1 |
| Castaldi, PA; Gorman, JJ | 2 |
| Bithell, TC; Parekh, SJ; Strong, RR | 1 |
| Mustard, JF; Niewiarowski, S; Regoeczi, E | 1 |
| Singh, K; Vézina, C | 1 |
| George, JN | 1 |
| Meyer, D | 1 |
| Hardisty, RM; Howard, MA; Hutton, RA | 1 |
| Burn, AM; Cooke, S; Sanderson, JH | 1 |
| Evensen, SA; Grotium, KA; Hovig, T; Solum, NO | 1 |
| O'Brien, JR | 1 |
| Kitzmiller, JL; Lang, JE; Lucas, WE; Yelenosky, PF | 1 |
| Brinkhous, KM; Mason, RG | 1 |
| Ardlie, NG | 1 |
| Mustard, JF; Niewiarowski, S; Regoeczi, E; Senyl, AF; Stewart, GJ | 1 |
| Caen, JP; Michel, H | 1 |
| Levine, PH | 1 |
| Douglas, AS; Hassanein, AA; McNicol, GP; Prentice, CR | 1 |
| De Gaetano, G; Donati, MB; Palester-Chlebowczyk, M; Vermylen, J | 1 |
| Hampton, JR; Nicholls, DG | 1 |
| Hilgard, P; Hohage, R; Minne, H; Schmitt, W; Ziegler, R | 1 |
| Etherington, M; O'Brien, JR; Tulevski, V | 1 |
| Cronberg, S | 1 |
| Budzyński, AZ; Marder, VJ; Rigollot, C; Solum, NO | 1 |
| Berman, HJ; McKinnon, EL; Tangen, O | 1 |
| Mitrakul, C | 1 |
| Glueck, CJ; Glueck, HI | 1 |
| Berman, HJ; Tangen, O; Wik, OK | 1 |
| Boneu, B; Conte, J; Suc, JM | 1 |
| Brener, BJ; Chesney, CM; Colman, RW; Darling, RC; Raines, JK | 1 |
| Alkjaersig, N; Etherington, M; Fletcher, A; Madgwick, T; O'Brien, JR; Tulevski, VG | 1 |
| Eurenius, E; Rothenberg, J | 1 |
| Fumarola, D; Pasquetto, N; Semeraro, N; Vermylen, J | 1 |
| Ardlie, NG; Han, P | 2 |
| Arapakis, G; Gardikas, C; Papayannis, AG; Stathakis, NE | 1 |
| Blench, SM; Brown, LJ; Hall, J; Stalker, AL | 1 |
| Douglas, AS; McNicol, GP; Turpie, AG | 1 |
| Bell, WR; Brown, CH; Jackson, DP; Shreiner, DP | 1 |
| Barton, BP; Chandler, AB; Shirasawa, K | 1 |
| Heinrich, D; Müller-Berghaus, G | 1 |
| Harbury, CB; Hershgold, JE; Schrier, SL | 1 |
| Howie, PW; McNicol, GP; Prentice, CR | 1 |
| Caen, JP; Cronberg, S | 1 |
| Raccuglia, G | 1 |
| Haslam, RJ; Rosson, GM | 1 |
| Larrieu, MJ | 1 |
| De Gaetano, G; Donati, MB; Dotremont, G; Michielsen, P; Vermylen, J | 1 |
| Caen, J; Michel, H; Sultan, Y | 1 |
| Caen, JP; Lukasiewicz, H; Sultan, Y; Vainer, H | 1 |
| Hawiger, J; Kloczewiak, M; Timmons, S | 2 |
| Caen, J; Dubernard, V; Legrand, C | 1 |
| Caen, JP; Dunn, FW; Lee, H; Soria, C; Soria, J; Thomaidis, A | 1 |
| Dupuy, E; Guillausseau, PJ; Lubetzki, J | 1 |
| Di Minno, G; Martinez, J; Murphy, S; Perussia, B; Shapiro, S; Thiagarajan, P; Trinchieri, G | 1 |
| Bennett, EM; Martin, MN; McEver, RP | 1 |
| Lansdorp, PM; Leeksma, OC; Tetteroo, PA; von dem Borne, AE | 1 |
| Ideura, T; Saito, H; Takeuchi, J | 1 |
| Jordan, J; Montgomery, RR; Schullek, J | 1 |
| Miyashita, C; Morgenstern, E; Reimers, HJ | 1 |
| Masiello, NC; Zucker, MB | 1 |
| Coller, BS; Gralnick, HR; Williams, SB | 1 |
| Marguerie, GA; Plow, EF | 4 |
| Brudzynski, TM; Budzynski, AZ; Morinelli, TA; Niewiarowski, S; Stewart, GJ | 1 |
| Kloczewiak, M; Kornecki, E; Morinelli, TA; Niewiarowski, S | 1 |
| Colman, RF; Colman, RW; Figures, WR; Mills, DC; Morinelli, TA; Niewiarowski, S | 1 |
| Colman, RF; Colman, RW; Figures, WR; Morinelli, TA; Niewiarowski, S | 1 |
| Bennett, JS; Burch, JW; Vilaire, G | 1 |
| Larrieu, MJ; Marguerie, GA; Plow, EF; Thomas-Maison, N | 1 |
| Cierniewski, CS; Janiak, A; Kowalska, MA; Krajewski, T | 1 |
| Guccione, MA; Harfenist, EJ; Kinlough-Rathbone, RL; Mustard, JF; Packham, MA | 1 |
| Ardaillou, N; Cherel, G; Marguerie, GA; Plow, EF | 1 |
| Cattaneo, M; Chahil, A; Kinlough-Rathbone, RL; Lam, SC; Mustard, JF; Packham, MA; Perry, DW; Vickers, JD | 1 |
| Colman, RW; Figures, WR; Kornecki, E; Morinelli, TA; Niewiarowski, S; Wachtfogel, Y | 1 |
| Bennett, JS; Cines, DB; Hoxie, JA; Leitman, SF; Vilaire, G | 1 |
| Budzynski, AZ; Kornecki, E; Morinelli, TA; Niewiarowski, S; Tuszynski, GP | 1 |
| Cierniewski, CS; Kowalska, MA | 1 |
| Colman, RW; Figures, WR | 1 |
| Seaman, GV | 1 |
| Riecker, G | 1 |
| Engerman, RL; Kern, TS | 1 |
| Castella, A; Kupinski, JM; Miller, JL; Ruggeri, ZM | 1 |
| Dickson, VM; Feuerstein, IA | 1 |
| Kinlough-Rathbone, RL; Mustard, JF; Packham, MA | 1 |
| Leung, LL | 1 |
| Gavrilov, VB; Khovratovich, VI | 1 |
| Mansouri, A; Perry, CA; Phillips, HM | 1 |
| Feuerstein, IA; Kush, J | 1 |
| Clemetson, KJ; McGregor, JL; McGregor, L; Renaud, S; Toor, B | 2 |
| Agam, G; Livne, A | 1 |
| Egan, JJ; Grant, RA; Johnson, MM; Peerschke, EI; Zucker, MB | 1 |
| Amtorp, O; Gormsen, J; Knudsen, JB; Skagen, K | 1 |
| Grant, RA; Peerschke, EI; Zucker, MB | 1 |
| Harfenist, EJ; Kinlough-Rathbone, RL; Mustard, JF; Packham, MA | 1 |
| Kaplan, JE; Malik, AB; Minnear, FL; Moon, DG | 1 |
| Emekli, NB; Gürsoy, AZ; Ugur, MS; Ulutin, ON; Yardimci, TU | 1 |
| Moncada, S; Radomski, M; Vargas, JR | 1 |
| Galanakis, DK; Peerschke, EI | 1 |
| Calles-Escandón, J; Córdova-Caballero, MS; Lanzetti-de-Peschard, C; Lozano-Castañeda, O; Padrós-Semorile, MR; Ruiz-Argüelles, GJ | 1 |
| Fazekas, F; Lechner, H; Ott, E | 1 |
| Benton, AM; Gerrard, JM; Kindom, SE; Michiel, T | 1 |
| Marguerie, G; Plow, EF | 1 |
| Hawiger, J; Parkinson, S; Timmons, S | 1 |
| Dormandy, JA | 1 |
| Harfenist, EJ; Mustard, JF; Packham, MA; Raychaudhuri, G | 1 |
| Patscheke, H | 1 |
| Dauzier, MJ; Kaplan, KL; Rose, S | 1 |
| Kinlough-Rathbone, RL; Mustard, JF; Winocour, PD | 1 |
| Avventi, GL; Bonadiman, L; Doni, MG; Meduri, F; Vassanelli, P | 1 |
| Inada, Y; Matsushima, A; Okada, M; Okamoto, H; Saito, Y | 1 |
| Gartner, TK; Phillips, DR; Williams, DC | 1 |
| Peerschke, EI; Zucker, MB | 2 |
| Grant, RA; Zucker, MB | 1 |
| Blombäck, B; Iwamoto, M; Söderman, S; Tomikawa, M | 1 |
| Bensch, KW; Forssmann, WG; Patscheke, H; Raida, M; Ruf, A; Schepky, AG; Schulz-Knappe, P; Sillard, R; Ständker, L | 1 |
| Chen, J; Grabarek, J; Groopman, JE; Herceg-Harjacek, L | 1 |
| Bouloux, P; Chronos, NA; Goodall, AH; Hjemdahl, P; Wilson, DJ | 1 |
| Bainton, D; Beswick, A; Elwood, PC; Fifield, R; Limb, ES; O'Brien, JR; Renaud, S | 1 |
| Francis, S; Jaraki, O; Loscalzo, J; Stamler, JS; Strauss, WE | 1 |
| Bray, PF; Dise, K; Faraday, N; Goldschmidt-Clermont, P | 1 |
| Chronos, NA; Cox, AD; Goodall, AH; Janes, SL; Wilson, DJ | 1 |
| Dobos, G; Gawaz, MP; Gurland, HJ; Mujais, SK; Schollmeyer, P; Späth, M | 1 |
| Agnelli, G; Callegari, P; Hauert, J; Iorio, A; Parise, P | 1 |
| Buller, NP; Chronos, NA; Goodall, AH; Hutton, RA; Janes, SL; Wilson, DJ | 1 |
| Bartley, T; Chen, J; Choi, ES; Hokom, M; Kato, T; Knudten, A; Li, YS; Nichol, JL; Ohashi, H; Skrine, J | 1 |
| Labrunie, P; Lévy, G; Lévy, PY; Teysseire, N; Valeix, B | 1 |
| Chen, H; Colman, RF; Colman, RW; Kumar, A; Puri, RN | 1 |
| Addo, JB; Bray, PF; Faraday, N; Goldschmidt-Clermont, PJ; Grigoryev, D | 1 |
| Bihour, C; Heilmann, E; Herbert, JM; Maffrand, JP; Nurden, A; Nurden, P; Savi, P | 1 |
| Chern, JW; Chou, TC; Ding, YA; Yen, MH | 1 |
| Ashby, B; Daniel, JL; Gazzaniga, PP; Pulcinelli, FM | 1 |
| Emery, JD; Lawrence, JB; Leifer, DW; Morrissey, JH; Moura, GL; Southern, P | 1 |
| Katoh, K; Mohri, H; Okubo, T; Tanabe, J | 1 |
| Daniel, JL; Gazzaniga, PP; Pulcinelli, FM; Riondino, S; Salganicoff, L | 1 |
| Feuerstein, IA; McClung, WG; Sheppard, JI | 1 |
| Hay, CR; Kamiguti, AS; Slupsky, JR; Zuzel, M | 1 |
| Frojmovic, MM; Mooney, RF; Wong, T | 2 |
| Amrani, DL; Derrick, JM; Gartner, TK | 1 |
| Huang, GW; Kosugi, T; Nakamura, M; Nong, HT | 1 |
| Burstein, SA; Dale, GL; George, JN; Heilmann, E; Hynes, LA | 1 |
| Cox, AD; Devine, DV | 1 |
| Mohri, H; Ohkubo, T | 1 |
| Estry, DW; Hogan, M; Klomparens, K; Mattson, JC | 1 |
| Goodall, AH; Janes, SL | 1 |
| Buoninconti, R; Coppola, L; Cozzolino, D; Giugliano, D; Giunta, R; Tirelli, A; Torella, R; Verrazzo, G | 1 |
| Kashiwaya, M; Takahashi, H; Tohgi, H; Watanabe, K | 1 |
| Bozarth, JM; Forsythe, MS; Mousa, SA; Reilly, TM | 1 |
| Braovac, S; Frojmovic, MM; Goldsmith, HL; McIntosh, F; Wong, T | 1 |
| Cierniewski, CS; Michalak, E; Pawlowska, Z; Walkowiak, B | 1 |
| Frojmovic, MM; Gerrard, JM; McNicol, A; Robertson, C; Searcy, GP; Wong, T | 1 |
| Huang, TF; Sheu, JR | 1 |
| Lüscher, EF; Weber, S | 1 |
| Cook, NS; Hagenbach, A; Metternich, R; Powling, M; Singh, J; Tapparelli, C; Zerwes, HG | 1 |
| Akkerman, JW; Gorter, G; van Willigen, G | 1 |
| Golding, LA; Harasaki, H; Tominaga, R | 1 |
| Cierniewski, CS; Krzeslowska, J; Pawlicki, L; Pawlowska, Z; Swiatkowska, M | 1 |
| Koomans, HA; Rabelink, TJ; Sixma, JJ; Zwaginga, JJ | 1 |
| Arisawa, M; Hadváry, P; Kamiyama, T; Satoh, T; Steiner, B; Watanabe, J; Yamashita, Y | 1 |
| Arisawa, M; Kamiyama, T; Satoh, T; Yamashita, Y | 1 |
| Belch, JJ; Lau, CS; McLaren, M; Saniabadi, A | 1 |
| Brommer, EJ; de Maat, MP; Kroft, LJ | 1 |
| Buysschaert, M; Chatelain, B; Donckier, J; el Khawand, C; Jamart, J; Lavenne, E; Moriau, M | 1 |
| Francis, SA; Jaraki, O; Keaney, JF; Loscalzo, J; Osborne, JA; Simon, DI; Singel, DJ; Stamler, JS | 1 |
| Holmsen, H; Klausen, H; Lie, RT; Thorsen, T | 1 |
| Vickers, JD | 1 |
| Grevelink, SA; Lerner, EA; Loscalzo, J; Youssef, DE | 1 |
| Feijge, MA; Heemskerk, JW; Hoyland, J; Mason, WT; Sage, SO; Vis, P | 1 |
| Budzynski, AZ; Khan, S; Kowalska, MA; Lasz, EC; McLane, MA; Niewiarowski, S; Trybulec, M | 1 |
| Kowalska, MA; Lu, W; McLane, MA; Niewiarowski, S; Silver, L; Trybulec, M | 1 |
| Anischuk, M; Belitser, N; Gorkun, O; Pozdnjakova, T; Veklich, Y | 1 |
| Bodary, S; Bunting, S; Chen, AB; Fei, DT; Lowe, J; McLean, JW; Napier, M | 1 |
| Haimovich, B; Ji, P; Kaneshiki, N | 1 |
| Alemany, M; Concord, E; Garin, J; Giles, A; Gulino, D; Marguerie, G; Vinçon, M | 1 |
| Boudignon-Proudhon, C; Criss, AB; Dieter, MG; Parise, LV; Wencel-Drake, JD | 1 |
| Kamiyama, T; Katoh, H; Nakamura, Y; Satoh, T; Uemura, F; Umino, T; Yokose, K | 1 |
| Bihour, C; Nurden, AT; Nurden, P; Raymond, JM; Smith, M | 1 |
| Lord, ST; Parise, LV; Rooney, MM | 1 |
| Bradford, HN; Colman, RW; DeLa Cadena, RA; Jameson, BA; Kunapuli, SP; Rick, L; Wassell, RP | 1 |
| Eguchi, S; Hayashi, J; Miyamura, H; Yamamoto, K | 1 |
| Burstein, SA; Dale, GL; Downs, T; Friese, P; Harrison, P; Lok, S; Peng, J; Wolf, RF | 1 |
| Hori, K; Matsubara, K; Sumi, H | 1 |
| Bihour, C; Humbert, M; Kunicki, TJ; Nurden, AT; Nurden, P; Piotrowicz, RS; Poujol, C | 1 |
| Colman, RW; Puri, RN | 1 |
| Brusamolino, A; Pareti, FI; Pellegrini, N; Simonetti, P; Stabile, F | 1 |
| Chiu, L; Faung, ST; Wang, CT | 1 |
| Borchert, G; Breton, M; Chap, H; Gironcel, D; Haricot, M; Kieffer, N; Payrastre, B; Racaud-Sultan, C | 1 |
| Jennings, LK; Mandrell, TD; White, MM | 1 |
| Ceuppens, JL; El Ghmati, SM; Stevens, EA; Van Hoeyveld, EM; Van Strijp, JG | 1 |
| Droste, DW; Kaps, M; Siemens, HJ; Sonne, M; Wagner, T | 1 |
| Frojmovic, MM; Searcy, GP; Wong, T | 1 |
| Lavelle, SM; Mhic Iomhair, M | 1 |
| Budzynski, AZ; Farrell, DH; Kowalska, MA; Lasz, EC; Niewiarowski, S; Wierzbicka, I | 1 |
| Brown, EA; Frojmovic, MM; Goldsmith, HL; Kasirer-Friede, A | 1 |
| Bennett, JS; Chan, C; DeGrado, WF; Mousa, SA; Vilaire, G | 1 |
| Avraham, H; Avraham, S; Raja, S | 1 |
| Bydlowski, SP; Chamone, DA; D'Amico, EA | 1 |
| Kawasaki, T; Kawashima, H; Maruyama, K; Sakai, Y; Shimizu, M; Takenaka, T; Taniuchi, Y | 1 |
| Kinlough-Rathbone, RL; Packham, MA; Perry, DW; Rand, ML | 1 |
| Fujimura, Y; Handa, M; Iijima, K; Ikeda, Y; Kitaguchi, T; Murata, M; Nakamura, K; Watanabe, K; Yoshioka, A | 1 |
| Cattaneo, M; Cazenave, JP; Gachet, C; Lombardi, R; Mannucci, PM; Ohlmann, P; Zighetti, ML | 1 |
| Askew, BC; Baldwin, JJ; Bednar, B; Bednar, RA; Claremon, DA; Cook, JJ; Gaul, SL; Glass, JD; Gorham, LM; Gould, RJ; Hamill, T; Hartman, GD; Holahan, MA; Hunt, CA; Lynch, JJ; Lynch, RJ; McIntyre, CJ; Prueksaritanont, T; Sitko, GR; Stranieri, MT | 1 |
| Bell, E; Foster, T; Höök, M; House-Pompeo, K; McDevitt, D; McIntire, L; Nanavaty, T; Turner, N | 1 |
| Bielek, E; Koller, E; Koller, F; Volf, I | 1 |
| Evanson, OA; Weiss, DJ | 1 |
| Fujiyoshi, T; Katada, J; Muramatsu, M; Takiguchi, Y; Uno, I | 1 |
| Badorc, A; Bernat, A; Bordes, MF; de Cointet, P; Herbert, JM; Lalé, A; Maffrand, JP; Petitou, M; Savi, P | 1 |
| Ahmad, G; Hsu, L; Kamiyama, M; Shido, K | 1 |
| Diamond, SL; Tandon, P | 1 |
| Basser, S; Heidinger, K; Jovin, IS; Müller-Berghaus, G; Taborski, U | 1 |
| Faraday, N; Rosenfeld, BA | 1 |
| Aoki, T; Honda, S; Okubo, M; Seki, J; Senzaki, K; Takahashi, F; Takasugi, H; Tanaka, A; Tomiyama, Y | 1 |
| Alevriadou, BR; Graham, DA; Huang, TC; Nelson, LD | 1 |
| Aguejouf, O; Belougne-Malfatti, E; Doutremepuich, C; Doutremepuich, F | 1 |
| Furihata, K; Hirota, M; Ishikawa, S; Katsuyama, T; Okumura, N; Sasaki, Y; Tozuka, M | 1 |
| de Groot, PG; Farrell, DH; Lord, ST; Rooney, MM; van Hemel, BM | 1 |
| Gawaz, M; Hiller, E; Holler, E; Kolb, HJ; Mempel, W; Neumeister, P; Pihusch, R; Salat, C; Sill, H; Wittmann, G | 1 |
| Hérault, JP; Herbert, JM; Li, N; Savi, P; Wallén, NH | 1 |
| Byzova, TV; Plow, EF | 1 |
| Martinson, EA; Marx-Grunwitz, A; Presek, P; Scheible, S | 1 |
| Goto, S; Hande, S; Ikeda, Y; Sakai, H | 1 |
| Krajewski, T; Mielicki, WP; Olas, B; Wachowicz, B | 1 |
| Bode, C; Böhrer, H; Gries, A; Gross, S; Martin, E; Peter, K | 1 |
| Huang, MH; Shen, AY; Teng, CM; Wang, JS | 1 |
| Cheung, AK; Green, W; Kozek-Langenecker, SA; Masaki, T; Mohammad, H; Mohammad, SF | 1 |
| Juvela, S; Niemi, T; Randell, T; Rosenberg, P; Tanskanen, P; Taxell, C | 1 |
| Holmes, MB; Schneider, DJ; Sobel, BE | 1 |
| Becker, A; Diebold, R; Doetschman, T; Hoying, JB; Ormsby, I; Yin, M | 1 |
| Barnard, MR; Bray, PF; Christie, DJ; Coleman, L; Furman, MI; Goldschmidt-Clermont, P; Hamlington, J; Hendrix, C; Kickler, T; Kundu, S; Mascelli, MA; Michelson, AD | 1 |
| Fusegawa, Y; Handa, S | 1 |
| Fisher, MJ; Giese, U; Harms, CS; Jakubowski, JA; Kinnick, MD; Lindstrom, TD; McCowan, JR; Mest, HJ; Morin, JM; Mullaney, JT; Paal, M; Rapp, A; Rühter, G; Ruterbories, KJ; Sall, DJ; Scarborough, RM; Schotten, T; Stenzel, W; Towner, RD; Um, SL; Utterback, BG; Wyss, VL | 1 |
| Agneskirchner, J; Bode, PA; Reininger, AJ; Spannagl, M; Wurzinger, LJ | 1 |
| Bode, C; Erbe, N; Gries, A; Herr, A; Holzmann, A; Martin, E; Motsch, J; Taut, F; Weimann, J | 1 |
| Barlage, S; Lackner, KJ; Schmitz, G; von Landenberg, C | 1 |
| Kounga, K; Lerner, EA; Mariano, F; Reddy, VB | 1 |
| Bonnefoy, A; Frojmovic, MM; Legrand, C; Liu, Q | 1 |
| Mayama, K; Munakata, A; Narita, M; Suzuki, Y; Takami, H; Tamai, Y | 1 |
| Doi, H; Ikeo, T; Karasawa, T; Katoh, M; Narita, H; Odawara, A; Takagi, M | 1 |
| Badimon, JJ; Chesebro, JH; Fuster, V; Rauch, U; Reis, ED; Roqué, M | 1 |
| Bielek, E; Koller, E; Koller, F; Moeslinger, T; Volf, I | 1 |
| Aguejouf, O; Belon, P; Doutremepuich, C; Malfatti, E | 1 |
| Assmann, G; Becker, P; Junker, R; Langer, C; Neufeld, M; Nofer, JR | 1 |
| Jennings, LK; Mondoro, TH; White, MM | 1 |
| Badimon, JJ; Chesebro, JH; Farkouh, ME; Fuster, V; Helft, G; Lev, EI; Osende, JI; Rodriguez, OJ; Worthley, SG; Zaman, AG | 1 |
| Daleskog, M; Hu, H; Li, N | 1 |
| Asai, F; Iwamura, R; Koike, H; Ogawa, T; Otsuguro, K; Sugidachi, A; Yoneda, K | 1 |
| Camerini, D; Gear, AR; Polanowska-Grabowska, RK; Raha, S; Suttitanamongkol, S; Viisoreanu, D | 1 |
| Chen, X; Du, XY; Liu, JW; Liu, P; Wu, XF; Xu, JM; Zhou, YC | 1 |
| Amo-Takyi, BK; Faridi, A; Heilmann, L; Klein, B; Rath, W; Von Tempelhoff, GF | 1 |
| Gietka, M; Kostka, B; Krajewska, U; Sikora, J | 1 |
| Basani, RB; Bennett, JS; D'Andrea, G; Kowalska, MA; Mitra, N; Poncz, M; Richberg, M; Vilaire, G | 1 |
| Akkerman, JW; Korporaal, SJ; Relou, IA; van Rijn, HJ | 1 |
| Jagodziński, P; Lizakowski, S; Rutkowski, B; Słomińska, E; Zdrojewski, Z | 1 |
| Albert, J; Daleskog, M; Wallén, NH | 1 |
| Pang, YZ; Su, JY; Tang, CS; Wang, PY; Yao, XH | 1 |
| Bayly, WM; Kingston, JK; Meyers, KM; Sellon, DC; Wardrop, KJ | 1 |
| Anglés-Cano, E; Corral, J; González-Conejero, R; Loyau, S; Lozano, ML; Martínez, C; Rivera, J; Vicente, V | 1 |
| Bennett, JS; Catella-Lawson, F; FitzGerald, GA; Kapoor, SC; Murphy, S; Qi, W; Rut, AR; Vilaire, G | 1 |
| Alfón, J; Fernández de Arriba, A; Gómez-Casajús, LA; Merlos, M | 1 |
| D'Agostino, RA; Feng, D; Larson, MG; Levy, D; Lindpaintner, K; Myers, RH; O'Donnell, CJ; Sutherland, PA; Tofler, GH | 1 |
| D'Agostino, RB; Feng, D; Larson, MG; Levy, D; Lindpaintner, K; Lipinska, I; Mittleman, M; Muller, JE; O'Donnell, CJ; Sutherland, PA; Tofler, GH | 1 |
| Matsuhashi, H; Matsumoto, M; Nakazawa, M | 1 |
| Avraham, H; Avraham, S; Fu, Y; Kaczmarek, E; Koziak, K; Park, SY | 1 |
| Altruda, F; Bosco, O; Calvez, R; Hirsch, E; Laffargue, M; Montrucchio, G; Tropel, P; Wymann, M | 1 |
| Schrör, K; Weber, AA | 1 |
| Ervin, AL; Peerschke, EI | 1 |
| Mielicki, WP; Olas, B; Wachowicz, B | 1 |
| Devine, DV; Maurer-Spurej, E | 1 |
| Fitzgerald, DJ; Fullard, J; Moran, N; Murphy, R; O'Neill, S; Ottridge, B | 1 |
| Jin, J; Kunapuli, SP; Quinton, TM; Rittenhouse, SE; Zhang, J | 1 |
| Ahmed, F; Alexandridis, P; Neelamegham, S; Shankaran, H | 1 |
| Akamatsu, S; Hisamichi, N; Ichihara, M; Inagaki, O; Kaku, S; Kawasaki, T; Matsumoto, Y; Moritani, Y; Nii, T; Sato, K; Shigenaga, T; Suzuki, Ki; Tomioka, K; Yanagisawa, I | 1 |
| Broberg, M; Eriksson, C; Nygren, H | 1 |
| Hermann, A; Schrör, K; Weber, AA | 1 |
| Frelinger, AL; Furman, MI; Jakubowski, JA; Jordan, RE; Marchese, PJ; Marciniak, SJ; Mascelli, MA; Michelson, AD | 1 |
| Brass, LF; Prevost, N; Tanaka, T; Woulfe, D | 1 |
| Barinagarrementería-Aldatz, F; Cantú-Brito, C; De la Peña-Díaz, A; González-Pacheco, H; Izaguirre-Avila, R; Quiroz-Martínez, A; Ramírez-Gutierrez, AE; Ruiz-Sandoval, JL | 1 |
| Aggarwal, A; Gennari, FJ; Kabbani, SS; Rimmer, JM; Schneider, DJ; Sobel, BE; Taatjes, DJ | 1 |
| Eriksson, M; Larsson, A; Lindahl, TL | 1 |
| Ekberg, K; Hjemdahl, P; Hu, H; Johansson, BL; Li, N | 1 |
| Gratacap, MP; Nieswandt, B; Offermanns, S; Schulte, V; Zywietz, A | 1 |
| Davies, AR; Glenn, JR; Heptinstall, S; Judge, HM; May, JA | 1 |
| Caen, JP; Combrié, R; Nurden, AT; Nurden, P; Poujol, C; Winckler, J | 1 |
| Jacobs, C; Kelm, M; Meila, D; Scharf, RE; Schrör, K; Strauer, BE; Weber, AA; Weber, S; Zotz, RB | 1 |
| Combrié, R; Conley, PB; Habib, A; Levy-Toledano, S; Nurden, AT; Nurden, P; Poujol, C; Pousseau, N; Winckler, J | 1 |
| Ginsberg, MH; Riederer, MA; Steiner, B | 1 |
| Handa, M; Ikeda, Y; Kadowaki, T; Koyasu, S; Matsubara, Y; Moroi, M; Nakajima, H; Oda, A; Suzuki, H; Terauchi, Y; Watanabe, N | 1 |
| Faridi, A; Heilmann, L; Klein, B; Mittermayer, C; Rath, W; von Tempelhoff, GF | 1 |
| Naik, MU; Naik, UP | 1 |
| Cornell, RF; Randolph, TR | 1 |
| Bradley, JD; Cain, VA; Feuerstein, GZ; Hua, TA; Kornhauser, DM; Martin, DE; Munzer, DA; Seiffert, D; Stern, AM; Tchinnes, MA; Thomas, BE | 1 |
| Alberti, L; Bennardini, F; Di Simplicio, P; Franconi, F; Miceli, M; Rao, GH; Seghieri, G | 1 |
| Broberg, M; Nygren, H | 1 |
| Abatzis, M; Biris, N; Konidou, G; Michalis, L; Mitsios, JV; Sakarellos, C; Sakarellos-Daitsiotis, M; Sideris, D; Soteriadou, K; Tselepis, AD; Tsikaris, V; Tsoukatos, D | 1 |
| BORN, GV; CROSS, MJ | 1 |
| HERTLER, D; MAXWELL, RE; MCLEAN, JR | 1 |
| CROSS, MJ | 1 |
| BRINKHOUS, KM; MASON, RG; READ, MS | 1 |
| Järemo, P; Lindahl, TL; Lysen, J; Milovanovic, M; Ramström, S; Richter, A | 1 |
| Inchiosa, MA; Nagappala, B; Pothula, S; Sanchala, VT | 1 |
| Abatzis, M; Biris, N; Elisaf, M; Goudevenos, J; Mitsios, JV; Sakarellos, C; Sakarellos-Daitsiotis, M; Soteriadou, K; Tambaki, AP; Tselepis, AD; Tsikaris, V; Tsoukatos, D | 1 |
| Coleman, LG; Gear, AR; Marcinkiewicz, M; Polanowska-Grabowska, RK | 1 |
| Byzova, TV; Chen, J; Chen, WS; Damron, DS; De, S; Hay, N | 1 |
| Alfonso, F; Angiolillo, DJ; Bañuelos, C; Bernardo, E; Escaned, J; Fernandez-Ortiz, A; Hernández-Antolín, R; Macaya, C; Moreno, R; Ramírez, C; Sabaté, M | 1 |
| Assmann, G; Bluethmann, H; Brodde, M; Engel, T; Herminghaus, G; Kehrel, BE; Morgenstern, E; Nofer, JR; Rust, S; Seedorf, U | 1 |
| Homer-Vaniasinkam, S; Naseem, KM; Nicolaou, A; Riba, R; Troxler, M | 1 |
| Herrmann, M; Kehrel, BE; Morgenstern, E; Niemann, S; Peters, G; Spehr, N; Van Aken, H | 1 |
| Aseichev, AV; Azizova, OA | 1 |
| Degen, JL; Isermann, BH; Palumbo, JS; Talmage, KE; Weiler, H; Zogg, M | 1 |
| Martus, P; Piorkowski, M; Rauch, U; Schultheiss, HP; Schwimmbeck, PL; Weikert, U | 1 |
| Homer-Vanniasinkam, S; Naseem, KM; Pasupathy, S | 1 |
| Goncalves, I; Jackson, SP; Nesbitt, WS; Yuan, Y | 1 |
| Balduini, C; Bertoni, A; Campus, F; Lova, P; Sinigaglia, F; Torti, M | 1 |
| Chen, P; Liu, JN; Sun, CX | 1 |
| Lindahl, TL; Mattsson, C; Nylander, S | 1 |
| Forslund, M; Hu, H; Li, N | 1 |
| Baumann, PQ; Schneider, DJ; Sobel, BE; Whitaker, DA | 1 |
| Liu, CZ; Shih, MH; Tsai, PJ | 1 |
| Farndale, RW; Naseem, KM; Riba, R; Sharifi, M | 1 |
| Frojmovic, M; Labarthe, B; Legrand, C | 1 |
| Chang, GT; Kim, CH; Kim, JH; Kim, JK; Kim, SH; Min, SY | 1 |
| Chang, HH; Chen, YF; Lin, CH; Lo, SJ; Sun, DS; Tsai, WJ; Yu, MS | 1 |
| Barnard, MR; Fox, ML; Frelinger, AL; Furman, MI; Li, Y; Linden, MD; Michelson, AD | 1 |
| Aguejouf, O; Belon, P; Doutremepuich, C; Eizayaga, FX | 1 |
| Hayashi, K; Kawasaki, T; Miyata, K; Moritani, Y; Saito, T; Takasaki, J; Taniguchi, M; Uchida, W; Uemura, T | 1 |
| Forslund, M; Hjemdahl, P; Ji, Q; Li, N; Razmara, M; Sudic, D | 1 |
| Bilodeau, ML; Cleator, J; Hamm, HE; Holinstat, M; McLaughlin, JN; Voss, B | 1 |
| Dyr, JE; Suttnar, J; Vanícková, M | 1 |
| Adam, F; Berrou, E; Bryckaert, M; Jandrot-Perrus, M; Kauskot, A; Mazharian, A; Nurden, P; Roger, S | 1 |
| Badimon, JJ; Choi, BG; Fuster, V; Vilahur, G; Viles-Gonzalez, JF; Vorchheimer, DA; Zafar, MU | 1 |
| Graham, AM; Homer-Vanniasinkam, S; Naseem, KM; Oberprieler, NG; Roberts, W | 1 |
| Auger, JM; Calaminus, SD; Insall, RH; Machesky, LM; McCarty, OJ; Pearce, AC; Watson, SP | 1 |
| Cawich, I; Chen, J; Dandapat, A; Deonikar, P; Hu, CP; Kavdia, M; Marwali, MR; Mehta, JL; Mohandas, B; Sawamura, T | 1 |
| Barbanti, M; Cerletti, C; de Gaetano, G; Di Fabio, G; Donati, MB; Maugeri, N | 1 |
| Boeckel, N; Lüscher, EF; Morgenstern, E | 1 |
| Bachoo, P; Brittenden, J; Croal, B; Ford, I; Greaves, M; Hillis, GS; Rajagopalan, S | 1 |
| Bliden, KP; Chaganti, SK; Dichiara, J; Gesheff, TB; Gurbel, PA; Kreutz, RP; Kreutz, Y; Tantry, US | 1 |
| Kroll, MH; Lassila, R; Reséndiz, JC | 1 |
| Du, X; Hay, N; Stojanovic, A; Yin, H | 1 |
| Hashimoto, I; Hoshi, R; Ikeda, H; Matsuo, R; Murata, S; Myronovych, A; Ohkohchi, N | 1 |
| Jagroop, IA; Mikhailidis, DP | 1 |
| Chen, JZ; Wang, HQ; Wang, SJ; Wang, XX; Yang, YM | 1 |
| Basani, RB; Bennett, JS; Degrado, WF; Kowalska, MA; Poncz, M; Soto, CS; Thornton, MA; Zhu, H | 1 |
| García, M; Schneider, DJ | 1 |
| Eto, K; Fujie, T; Handa, M; Ikeda, Y; Maekawa, I; Maruyama, H; Okamura, Y; Takeoka, S | 1 |
| Furudate, N; Oyama, E; Senuki, K; Takahashi, H | 1 |
| Lozano, ML; Martínez, C; Navarro-Núñez, L; Rivera, J; Vicente, V | 1 |
| Ak, K; Arsan, S; Eksioglu-Demiralp, E; Iqbal, O; Isbir, S; Tetik, S; Yardimci, T | 1 |
| Hammerschmidt, S; Heilmann, C; Kehrel, BE; Niemann, S; Peters, G; Rennemeier, C | 1 |
| Eliautou, S; Gachet, C; Lanza, F; Mangin, PH; Walter, U | 1 |
| Boldt, J; Mengistu, A | 1 |
| Chen, SJ; Guo, AG; Lu, P; Qin, YF; Zhang, ST | 1 |
| Al-Mondhiry, H; Ballard, JO; McGarvey, V | 1 |
| Egorihina, MN; Levin, GY | 1 |
| Antunes, E; Baldissera, L; de Mello, GC; Monteiro, PF; Morganti, RP | 1 |
| Dong, JF; Guthikonda, S; Kleiman, NS; Mangalpally, KK; Siqueiros-Garcia, A; Vaduganathan, M | 1 |
| Avallone, L; Cestaro, A; Lombardi, P; Mastellone, V; Pelagalli, A; Pero, ME; Signoriello, S | 1 |
| Carriveau, R; Heeney, R; Kaur, H; Mutus, B; Sosne, G | 1 |
| Bernlochner, I; Braun, S; Jaitner, J; Kastrati, A; Mehilli, J; Morath, T; Schömig, A; Sibbing, D; Stegherr, J; Steinhubl, S; von Beckerath, N | 1 |
| Bu, Y; Hwang, DS; Jang, W; Jo, IY; Kang, H; Kim, JI; Lee, BJ; Lee, W; Lew, JH; Maeng, S; Min, K; Park, JW; Yoo, HH | 1 |
| Asai, T; Chiba, M; Handa, M; Ikeda, Y; Korenaga, M; Oku, N; Tagawa, T; Takeoka, S; Tokutomi, K; Watanabe, N | 1 |
| Brunini, TM; Lugon, JR; Martins, MA; Mendes-Ribeiro, AC; Moss, MB; Pereira, NR; Santos, SF; Siqueira, MA | 1 |
| Chen, ZY; Inoue, Y; Iwai, T; Terasaki, H; Umeda, M; Yu, KM | 1 |
| Haaland, HD; Holmsen, H | 1 |
| Bassler, N; Dezfouli, S; Hickey, MJ; Hohmann, JD; Jackson, S; Jia, F; Krajewski, S; Kurz, J; Nandurkar, H; Peter, K; Selan, C; Straub, A; Wendel, HP; Westein, E; Yuan, Y | 1 |
| Brunini, TM; Cascarelli, PG; de Meirelles, LR; Matsuura, C; Mendes-Ribeiro, AC; Pereira, NR; Resende, Ade C; Salgado, A | 1 |
| De Chaumont, C; Lombardi, F; Moran, N; Shields, DC | 1 |
| Cho, JY; Kim, GS; Kim, MJ; Kim, S; Kim, SK; Kim, TH; Lee, IK; Oh, WJ; Park, HJ; Park, JY; Rhee, MH; Seo, GS; Yun, BS | 1 |
| He, Q; Hodgson, WC; Li, H; Li, J; Wen, H; Xiao, B; Yu, X; Zhang, K; Zhou, B | 1 |
| Ding, Z; Du, H; Liu, G; Pan, C; Wei, X; Ye, J; Zhang, S; Zhang, Y | 1 |
| Doi, M; Hagisawa, K; Handa, M; Iwaya, K; Katsuno, S; Kinoshita, M; Nishikawa, K; Saitoh, D; Sakamoto, T; Seki, S; Shono, S; Suzuki, H; Takeoka, S; Yanagawa, R | 1 |
| Allison, GL; Lowe, GM; Rahman, K | 1 |
| Cienfuegos-Jovellanos, E; de Roos, B; Duthie, GG; Horgan, GW; Kroon, PA; Ostertag, LM; Saha, S; Wood, S | 1 |
| Hatoya, S; Imai, H; Inaba, T; Izawa, T; Kanegi, R; Kawate, N; Kuwamura, M; Nishimura, T; Sugiura, K; Takahashi, M; Tamada, H; Tanaka, M; Wijewardana, V; Yamate, J | 1 |
| Ekman, B; Landberg, E; Lindahl, TL; Tillmar, L; Wahlberg, J | 1 |
| Doi, M; Fujiyama, A; Handa, M; Ikeda, Y; Maruyama, T; Ogaki, S; Okamura, Y; Otagiri, M; Taguchi, K; Takeoka, S; Ujihira, H; Watanabe, H | 1 |
| Conyers, JL; Dong, JF; Fu, Y; Li, M; Liu, L; Liu, X; Yang, X; Zaske, AM; Zhang, J; Zhang, Y; Zhou, Z | 1 |
| Doi, M; Fujiyama, A; Handa, M; Ikeda, Y; Maruyama, T; Otagiri, M; Taguchi, K; Takeoka, S; Ujihira, H; Watanabe, H | 1 |
| Jiang, LX; Jin, YY; Qu, ZY; Shang, L; Wang, YC; Xing, YL; Yu, XN; Zhang, AA | 1 |
| Harder, S; Klinkhardt, U; Kuczka, K; Meyer dos Santos, S; Nelson, K; Picard-Willems, B | 1 |
| Kim, HH; Kim, JL; Kim, YY; Kwon, HK; Kwon, HW; Lee, DH; Lee, JJ; Lim, DH; Nam, GS; Park, HJ; Shin, JH | 1 |
| Doi, M; Hagisawa, K; Handa, M; Iwaya, K; Kinoshita, M; Nishida, Y; Nishikawa, K; Saitoh, D; Seki, S; Suzuki, H; Takeoka, S; Yanagawa, R | 1 |
| Handa, M; Hashimoto, M; Ikeda, Y; Maruyama, T; Ogaki, S; Otagiri, M; Taguchi, K; Takeoka, S; Watanabe, H | 1 |
| Bijak, M; Miller, E; Miller, S; Morel, A; Rywaniak, J; Saluk, J | 1 |
| Li, JY; Liu, GR; Liu, XW; Ma, N; Mohamed, I; Yang, YJ; Zhang, JY | 1 |
| Banerjee, A; Chapman, MP; D'Alessandro, A; Gonzalez, E; Hansen, KC; Moore, EE; Moore, HB; Morton, AP; Sauaia, A; Silliman, CC; Slaughter, AL | 1 |
| Hu, Q; Liu, Z; Wang, C; Wu, J; Xu, J; Xue, W; Zhang, Y | 1 |
| Kubilius, R; Mongirdienė, A | 1 |
| Hagisawa, K; Handa, M; Iwaya, K; Kinoshita, M; Miyawaki, H; Miyazaki, H; Nishida, Y; Saitoh, D; Sato, S; Seki, S; Shono, S; Suzuki, H; Takeoka, S | 1 |
| Attwood, A; Cardigan, R; Furnell, A; Garner, SF; Goodall, AH; Harrison, P; Jones, CI; Kahan, BC; Kelly, AM; Ouwehand, WH | 1 |
| Biolik, G; Kokot, M; Pawlicki, K; Święszek, A; Sznapka, M; Ziaja, D; Ziaja, K | 1 |
| Boeck, M; Etzel, J; Kobsar, A; Koessler, A; Koessler, J; Schwarz, M; Weber, K | 1 |
| Bijak, M; Dziedzic, A; Saluk-Bijak, J; Szelenberger, R | 1 |
| Brophy, DF; Brophy, GM; Contaifer, D; López, JA; Martin, EJ; Mohammed, BM; Newton, JC; Saunders, JL; Spiess, BD; St John, AE; Ward, KR; White, NJ | 1 |
| Dutta, S; Kalita, B; Mukherjee, AK | 1 |
| Hagisawa, K; Kinoshita, M; Saitoh, D; Sakai, H; Seki, S; Takeoka, S; Takikawa, M | 1 |
| Boeck, M; Klingler, P; Kobsar, A; Koessler, A; Koessler, J; Schuepferling, A; Weber, K | 1 |
| Bramer, LM; Frohnert, BI; Norris, JM; Reehl, SM; Rewers, M; Steck, AK; Waugh, K; Webb-Robertson, BJ | 1 |
| Hagisawa, K; Ishida, O; Kinoshita, M; Suzuki, H; Takeoka, S; Takikawa, M; Tsutsumi, K; Yamanaka, N | 1 |
| Abe, H; Endo, K; Miyata, S; Nogawa, M; Satake, M; Shiba, M | 1 |
| Ivaska, J; Kasirer-Friede, A; Peuhu, E; Shattil, SJ | 1 |
| Bao, F; Dai, KS; Ge, XX; Ke, XY; Yan, R; Yang, MN; Ye, HL; Yuan, LX | 1 |
| Chernyshenko, VO; Hudz, IA; Hula, NM; Kasatkina, LO; Klimashevskyi, VM; Kosiakova, HV; Platonova, TM; Tkachenko, OS; Urvant, LP | 1 |
| de Groot, PG; de Laat, B; Heemskerk, JWM; Roest, M; Swieringa, F; Zou, J | 1 |
| Ding, LP; Do, HP; Ge, WH; Li, YC; Liu, T; Shao, TF; Wang, R; Xu, MM; Yi, MM; Zhuang, Z | 1 |
| Hagisawa, K; Ishida, O; Kearney, BM; Kinoshita, M; Nakashima, H; Takeoka, S; Tsutsumi, K; Yamanaka, N | 1 |
| Grasselli, G; Meli, A; Panigada, M | 1 |
| Coxon, FP; Jalal, MM; Mutch, NJ; Whyte, CS | 1 |
19 review(s) available for adenosine diphosphate and fibrinogen
| Article | Year |
|---|---|
[The role of adhesive proteins and membrane interactions in the processes of thrombocyte aggregation].
Topics: Adenosine Diphosphate; Blood Platelets; Cell Membrane; Culture Media; Fibrinogen; Fibronectins; Humans; In Vitro Techniques; Intercellular Junctions; Microscopy, Electron; Platelet Adhesiveness; Platelet Aggregation; Thrombin | 1991 |
Macromolecules that link platelets following vessel wall injury.
Topics: Adenosine Diphosphate; Blood Platelets; Blood Vessels; Cyclic AMP; Fibrinogen; Humans; Platelet Adhesiveness; Platelet Aggregation; Platelet Membrane Glycoproteins; von Willebrand Factor | 1987 |
The platelet fibrinogen receptor.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Binding Sites; Blood Platelets; Cations, Divalent; Collagen; Epinephrine; Fibrinogen; Fibronectins; Glycoproteins; Humans; Kinetics; Membrane Proteins; Platelet Aggregation; Platelet Membrane Glycoproteins; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Receptors, Cell Surface; Thrombin; Thrombospondins; von Willebrand Factor | 1985 |
[Interaction of fibrinogen with platelets. Review].
Topics: Adenosine Diphosphate; Blood Platelets; Carbohydrate Conformation; Carbohydrates; Fibrinogen; Glycoproteins; Humans; Hydrogen-Ion Concentration; Membrane Proteins; Platelet Aggregation; Platelet Membrane Glycoproteins; Protein Conformation; Receptors, Cell Surface; Temperature; Thrombospondins | 1985 |
Platelet activation: role of an ADP receptor.
Topics: Adenosine; Adenosine Diphosphate; Binding Sites; Blood Platelets; Cell Membrane; Collagen; Cytoplasmic Granules; Fibrinogen; Humans; Models, Theoretical; Molecular Weight; Peptide Hydrolases; Platelet Aggregation; Prostaglandin Endoperoxides; Receptors, Cell Surface; Receptors, Purinergic | 1986 |
Biological actions of prostacyclin and its pharmacological use in platelet studies.
Topics: Adenosine Diphosphate; Adenylyl Cyclases; Animals; Blood Platelets; Blood Preservation; Calcium; Collagen; Cyclic AMP; Drug Stability; Enzyme Activation; Epoprostenol; Fibrinogen; Humans; Microscopy, Electron; Platelet Aggregation; Thromboxane A2; Thromboxane B2 | 1985 |
Fibrinogen and platelet function.
Topics: Adenosine Diphosphate; Affinity Labels; Binding Sites; Blood Platelets; Cross-Linking Reagents; Fibrinogen; Fibronectins; Humans; Immunosorbent Techniques; Macromolecular Substances; Molecular Weight; Peptide Fragments; Photochemistry; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptors, Cell Surface; von Willebrand Factor | 1985 |
Platelet membrane components and receptors.
Topics: Adenosine Diphosphate; Blood Coagulation Factors; Blood Platelets; Cell Membrane; Fibrinogen; Glycoproteins; Hematology; Humans; Membrane Fluidity; Prostaglandin Endoperoxides, Synthetic; Receptors, Cell Surface; Receptors, Prostaglandin | 1987 |
Endothelium as a modulator of platelet reactivity.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Antithrombin III; Blood Coagulation; Blood Platelets; Endothelium; Epoprostenol; Factor IX; Factor V; Factor Va; Factor X; Factor Xa; Fibrinogen; Heparin; Humans; Platelet Adhesiveness; Platelet Aggregation; Vasodilation | 1985 |
Platelet aggregation by large molecules.
Topics: Adenosine Diphosphate; Antigen-Antibody Complex; Binding Sites; Blood Platelets; Carbon Radioisotopes; Centrifugation, Density Gradient; Collagen; Complement System Proteins; Edetic Acid; Fibrinogen; Heparin; Humans; Hydrazines; Immunoglobulin G; Molecular Weight; Platelet Adhesiveness; Polymers; Serotonin; Stimulation, Chemical; Time Factors; Zymosan | 1973 |
The functional physiology of blood platelets.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Adsorption; Biological Transport; Blood Platelets; Cell Membrane; Fibrinogen; Hemostasis; Platelet Adhesiveness; Potassium | 1972 |
Heparin, platelets, and venous thrombosis.
Topics: Adenosine Diphosphate; Blood Coagulation Factors; Blood Platelets; Depression, Chemical; Fibrinogen; Heparin; Humans; Iodine Radioisotopes; Lipoprotein Lipase; Platelet Adhesiveness; Postoperative Complications; Thrombophlebitis | 1973 |
Fibrinogen: requirement for platelet aggregation and adhesion.
Topics: Adenosine Diphosphate; Adsorption; Afibrinogenemia; Animals; Blood Platelets; Blood Proteins; Calcium; Fibrinogen; Glass; Hemostasis; Humans; In Vitro Techniques; Magnesium; Microscopy, Electron; Platelet Adhesiveness; Snakes; Species Specificity; Swine; Thrombin; Thrombosis; Venoms | 1972 |
Mechanism of platelet aggregation and release: their possible role in vascular injury.
Topics: Adenosine Diphosphate; Animals; Anti-Inflammatory Agents; Arteriosclerosis; Blood Coagulation; Blood Platelets; Blood Proteins; Blood Vessels; Collagen; Disseminated Intravascular Coagulation; Fibrin; Fibrinogen; Glass; Graft Rejection; Hemostasis; Humans; Ischemia; Kidney Transplantation; Platelet Adhesiveness; Platelet Aggregation; Thrombosis; Transplantation, Homologous | 1973 |
Characteristics of an ADP receptor mediating platelet activation.
Topics: Adenosine; Adenosine Diphosphate; Adenylyl Cyclases; Binding Sites; Blood Platelets; Cell Membrane; Fibrinogen; Receptors, Cell Surface; Receptors, Purinergic | 1984 |
Plasma protein interactions at biological interfaces.
Topics: Adenosine Diphosphate; Adsorption; Animals; Blood Coagulation; Blood Platelets; Blood Proteins; Calcium; Chemical Phenomena; Chemistry; Electrophysiology; Endothelium; Fibrinogen; Hemostasis; Humans; Hydrogen-Ion Concentration; Magnesium; Platelet Adhesiveness; Platelet Aggregation; Surface Properties | 1983 |
Haemorheological aspects of thrombosis.
Topics: Adenosine Diphosphate; Arteries; Blood Flow Velocity; Blood Viscosity; Erythrocytes; Fibrinogen; Hematocrit; Humans; Myocardial Infarction; Platelet Aggregation; Thrombosis | 1980 |
The formation of the haemostatic plug--a special case of platelet aggregation. An experiment and a survey of the literature.
Topics: Adenosine Diphosphate; Calcium; Fibrinogen; Fixatives; Formaldehyde; Humans; Platelet Activation; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptor Aggregation | 1993 |
Reversible Platelet Integrin αIIbβ3 Activation and Thrombus Instability.
Topics: Actomyosin; Adenosine Diphosphate; Animals; Blood Platelets; Fibrin; Fibrinogen; Mice; Phosphatidylinositols; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Kinase C; Proto-Oncogene Proteins c-akt; Thrombosis; von Willebrand Factor | 2022 |
25 trial(s) available for adenosine diphosphate and fibrinogen
| Article | Year |
|---|---|
The effect of a slow release formulation of bezafibrate on lipids, glucose homeostasis, platelets and fibrinogen in type II diabetics: a pilot study.
Topics: Adenosine Diphosphate; Bezafibrate; Blood Glucose; Blood Platelets; Cholesterol; Collagen; Delayed-Action Preparations; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Female; Fibrinogen; Homeostasis; Humans; Lipids; Lipoproteins, HDL; Lipoproteins, LDL; Male; Middle Aged; Pilot Projects; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Triglycerides | 1990 |
Platelet function studies before and after operation and the effect of postoperative thrombosis.
Topics: Adenosine Diphosphate; Adult; Aged; Aspirin; Blood Cell Count; Blood Platelets; Chromatography; Collagen; Epinephrine; Female; Fibrinogen; Humans; Iodine Radioisotopes; Leg; Male; Middle Aged; Neoplasms; Placebos; Platelet Adhesiveness; Postoperative Complications; Radionuclide Imaging; Surgical Procedures, Operative; Thrombin; Thrombosis | 1974 |
Hemorheological and cardiovascular responses to beta-endorphin and naloxone in healthy subjects and in patients with essential hypertension.
Topics: Adenosine Diphosphate; Adult; beta-Endorphin; Blood Pressure; Blood Viscosity; Cardiovascular System; Female; Fibrinogen; Heart Rate; Hematocrit; Humans; Hypertension; Male; Middle Aged; Naloxone; Platelet Aggregation; Rheology | 1994 |
The effect of ticlopidine upon plasma fibrinogen levels in patients undergoing suprapubic prostatectomy.
Topics: Acenocoumarol; Adenosine Diphosphate; Drug Evaluation; Fibrinogen; Humans; Male; Platelet Aggregation; Prostatectomy; Ticlopidine | 1993 |
Effects of moderate consumption of red wine on platelet aggregation and haemostatic variables in healthy volunteers.
Topics: Adenosine Diphosphate; Adult; Collagen; Cross-Over Studies; Ethanol; Fibrinogen; Hemostasis; Humans; Male; Middle Aged; Plasminogen; Platelet Aggregation; Platelet Aggregation Inhibitors; Tissue Plasminogen Activator; von Willebrand Factor; Wine | 1996 |
Hemostaseologic and hematologic parameters with aspirin and ticlopidine treatment in patients with cerebrovascular disease: a cross-over study.
Topics: Adenosine Diphosphate; Aged; Aspirin; Cerebrovascular Disorders; Collagen; Cross-Over Studies; Epinephrine; Female; Fibrinogen; Hemostasis; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Prospective Studies; Ticlopidine | 1996 |
Pretreatment of human platelets with plasmin inhibits responses to thrombin, but potentiates responses to low concentrations of aggregating agents, including the thrombin receptor activating peptide, SFLLRN.
Topics: Adenosine Diphosphate; Blood Platelets; Calcium; Cytoplasmic Granules; Cytosol; Drug Synergism; Fibrinogen; Fibrinolysin; Fibrinolytic Agents; Humans; In Vitro Techniques; Peptide Fragments; Platelet Aggregation; Receptors, Thrombin; Serotonin; Thrombin | 1997 |
The effect of intravenously administered magnesium on platelet function in patients after cardiac surgery.
Topics: Adenosine Diphosphate; Aged; Blood Platelets; Collagen; Coronary Artery Bypass; Double-Blind Method; Fibrinogen; Flow Cytometry; Humans; In Vitro Techniques; Infusions, Intravenous; Magnesium; Male; Middle Aged; P-Selectin; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Postoperative Period | 1999 |
Effects of nonsteroidal anti-inflammatory drugs on hemostasis in patients with aneurysmal subarachnoid hemorrhage.
Topics: Acetaminophen; Adenosine Diphosphate; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antithrombin III; Blood Coagulation; Blood Platelets; Cerebral Hemorrhage; Female; Fibrinogen; Follow-Up Studies; Hematoma; Hemostasis; Humans; Intracranial Aneurysm; Ketoprofen; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Risk Factors; Safety; Subarachnoid Hemorrhage | 1999 |
Variable responses to inhibition of fibrinogen binding induced by tirofiban and eptifibatide in blood from healthy subjects.
Topics: Adenosine Diphosphate; Adult; Dose-Response Relationship, Drug; Eptifibatide; Female; Fibrinogen; Flow Cytometry; Humans; Male; Middle Aged; P-Selectin; Peptides; Platelet Aggregation Inhibitors; Protein Binding; Tirofiban; Tyrosine | 1999 |
Randomized, placebo-controlled, blinded and cross-matched study on the antiplatelet effect of inhaled nitric oxide in healthy volunteers.
Topics: Adenosine Diphosphate; Administration, Inhalation; Adult; Blood Coagulation Tests; Collagen; Dose-Response Relationship, Drug; Double-Blind Method; Female; Fibrinogen; Flow Cytometry; Humans; Leukocyte Count; Male; Matched-Pair Analysis; Nitrates; Nitric Oxide; P-Selectin; Placebos; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Platelet Glycoprotein GPIIb-IIIa Complex; Sex Factors; Time Factors | 2000 |
Acute antithrombotic effect of a front-loaded regimen of clopidogrel in patients with atherosclerosis on aspirin.
Topics: Adenosine Diphosphate; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Double-Blind Method; Drug Therapy, Combination; Fibrinogen; Fibrinolytic Agents; Humans; Perfusion; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine; Time Factors | 2000 |
[The concentration of adenine nucleotides in platelets of patients with primary chronic glomerulonephritis].
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adult; Blood Platelets; Cholesterol; Cholesterol, LDL; Chromatography, High Pressure Liquid; Chronic Disease; Female; Fibrinogen; Glomerulonephritis; Humans; Male; Middle Aged; Nephrotic Syndrome; Platelet Activation; Serum Albumin; Triglycerides | 2000 |
Clopidogrel inhibits platelet adhesion and platelet-dependent mitogenesis in vascular smooth muscle cells.
Topics: Adenosine Diphosphate; Adult; Animals; Blood Platelets; Cattle; Cell Culture Techniques; Cell Division; Clopidogrel; Culture Media, Conditioned; DNA Replication; Fibrinogen; Humans; Male; MAP Kinase Signaling System; Muscle, Smooth, Vascular; Paracrine Communication; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine | 2002 |
Effect of clopidogrel on platelet aggregation and plasma concentration of fibrinogen in subjects with cerebral or coronary atherosclerotic disease.
Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Clopidol; Collagen; Coronary Artery Disease; Family Health; Fibrinogen; Humans; Intracranial Arteriosclerosis; Male; Middle Aged; Platelet Aggregation; Platelet Function Tests | 2002 |
Effects of the glycoprotein IIb/IIIa antagonist Roxifiban on P-selectin expression, fibrinogen binding, and microaggregate formation in a phase I dose-finding study: no evidence for platelet activation during treatment with a glycoprotein IIb/IIIa antagon
Topics: Adenosine Diphosphate; Adult; Amidines; Biomarkers; Dose-Response Relationship, Drug; Female; Fibrinogen; Humans; Isoxazoles; Male; P-Selectin; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Prodrugs; Receptors, Thrombin | 2003 |
The effect of preoperative antiplatelet/anticoagulant prophylaxis on postoperative blood loss in cardiac surgery.
Topics: Adenosine Diphosphate; Aged; Anticoagulants; Body Temperature; Cardiac Surgical Procedures; Clopidogrel; Coronary Artery Bypass; Double-Blind Method; Female; Fibrinogen; Hemostasis; Heparin; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Premedication; Prospective Studies; Purinergic P2 Receptor Antagonists; Ticlopidine | 2004 |
Is a 300 mg clopidogrel loading dose sufficient to inhibit platelet function early after coronary stenting? A platelet function profile study.
Topics: Adenosine Diphosphate; Clopidogrel; Coronary Vessels; Female; Fibrinogen; Flow Cytometry; Humans; Male; Middle Aged; P-Selectin; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Platelet Glycoprotein GPIIb-IIIa Complex; Premedication; Stents; Thrombosis; Ticlopidine; von Willebrand Factor | 2004 |
ADP induced platelet degranulation in healthy individuals is reduced by clopidogrel after pretreatment with atorvastatin.
Topics: Adenosine Diphosphate; Adolescent; Adult; Atorvastatin; Cell Degranulation; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Fibrinogen; Heptanoic Acids; Humans; Middle Aged; P-Selectin; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Pyrroles; Ticlopidine | 2004 |
Normalization of platelet reactivity in clopidogrel-treated subjects.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Aspirin; Blood Platelets; Clopidogrel; Collagen; Coronary Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fibrinogen; Humans; Male; Pilot Projects; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Transfusion; Platelet-Rich Plasma; Postoperative Hemorrhage; Receptors, Thrombin; Recovery of Function; Reference Values; Ticlopidine; Time Factors | 2007 |
Platelet function measured by VerifyNow identifies generalized high platelet reactivity in aspirin treated patients.
Topics: Adenosine Diphosphate; Aged; Aged, 80 and over; Arachidonic Acid; Aspirin; Collagen; Coronary Artery Disease; Cross-Over Studies; Double-Blind Method; Female; Fibrinogen; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Function Tests; von Willebrand Factor | 2007 |
Clopidogrel provides significantly greater inhibition of platelet activity than aspirin when combined with atorvastatin after coronary artery bypass grafting: a prospective randomized study.
Topics: Adenosine Diphosphate; Aged; Aspirin; Atorvastatin; Clopidogrel; Comorbidity; Coronary Artery Bypass; Coronary Disease; Drug Therapy, Combination; Female; Fibrinogen; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Lipoproteins, LDL; Male; Middle Aged; P-Selectin; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Postoperative Complications; Prospective Studies; Pyrroles; Ticlopidine | 2010 |
A new plasma-adapted hydroxyethyl starch preparation: in vitro coagulation studies.
Topics: Adenosine Diphosphate; Adult; Blood Coagulation; Blood Coagulation Tests; Blood Platelets; Clot Retraction; Collagen; Fibrinogen; Hemoglobins; Humans; Hydroxyethyl Starch Derivatives; Male; Pharmaceutical Solutions; Plasma Substitutes; Platelet Aggregation; Platelet Function Tests; Thrombelastography; Whole Blood Coagulation Time | 2010 |
Platelet signalling networks: pathway perturbation demonstrates differential sensitivity of ADP secretion and fibrinogen binding.
Topics: Adenosine Diphosphate; Blood Platelets; Female; Fibrinogen; Humans; Intracellular Signaling Peptides and Proteins; Male; Models, Biological; Phosphatidylinositol 3-Kinases; Platelet Adhesiveness; Platelet Glycoprotein GPIIb-IIIa Complex; Protein-Tyrosine Kinases; Receptors, Purinergic P2Y; Receptors, Purinergic P2Y12; Signal Transduction; Syk Kinase | 2012 |
Flavan-3-ol-enriched dark chocolate and white chocolate improve acute measures of platelet function in a gender-specific way--a randomized-controlled human intervention trial.
Topics: Adenosine Diphosphate; Adult; Aged; Biological Availability; Blood Platelets; Cacao; Candy; Female; Fibrinogen; Flavonoids; Humans; Male; Middle Aged; P-Selectin; Platelet Aggregation; Receptors, Thrombin; Sex Factors; Young Adult | 2013 |
639 other study(ies) available for adenosine diphosphate and fibrinogen
| Article | Year |
|---|---|
Platelet aggregation in portal cirrhosis.
Topics: Adenosine Diphosphate; Blood Cell Count; Blood Coagulation Tests; Blood Platelets; Fibrin Fibrinogen Degradation Products; Fibrinogen; Humans; Liver Cirrhosis; Platelet Aggregation; Serum Globulins; Thrombin | 1976 |
Factors responsible for ADP-induced release reaction of human platelets.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aspirin; Citrates; Fibrinogen; gamma-Globulins; Hemophilia A; Heparin; Hirudins; Humans; Magnesium; Phenylbutazone; Phosphates; Platelet Adhesiveness; Platelet Aggregation; Serum Albumin; Sulfinpyrazone; Thrombin | 1975 |
A new abnormality of platelet functions. Association of storage pool disease (thrombocytopathia A) with impaired reactivity of platelets to collagen.
Topics: Adenosine Diphosphate; Aged; Aspirin; Blood Platelet Disorders; Blood Platelets; Collagen; Fibrinogen; Glucuronidase; Humans; Male; Platelet Aggregation; Serotonin | 1975 |
Bovine fibrinogen-induced 14C-serotonin and other compounds release from human blood platelets.
Topics: Acid Phosphatase; Adenosine; Adenosine Diphosphate; Amitriptyline; Animals; Blood Platelets; Cattle; Collagen; Fibrinogen; Humans; Phentolamine; Phosphoenolpyruvate; Platelet Aggregation; Platelet Factor 3; Propranolol; Serotonin | 1975 |
Fibrinogen and ADP-induced platelet aggregation.
Topics: Adenosine; Adenosine Diphosphate; Animals; Blood Platelets; Chromium Radioisotopes; Edetic Acid; Fibrinogen; Humans; Iodine Radioisotopes; Platelet Aggregation; Prostaglandins E; Rabbits | 1978 |
Platelet dysfunction in patients with vitamin B12 deficiency.
Topics: Adenosine Diphosphate; Aged; Anemia, Pernicious; Blood Cell Count; Blood Coagulation Tests; Blood Platelet Disorders; Collagen; Epinephrine; Female; Fibrinogen; Hemoglobins; Humans; Male; Middle Aged; Platelet Aggregation; Ristocetin; Thrombocytopenia; Vitamin B 12 | 1979 |
The effect of pretreatment of human or rabbit platelets with chymotrypsin on their responses to human fibrinogen and aggregating agents.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Chymotrypsin; Collagen; Edetic Acid; Egtazic Acid; Fibrinogen; Humans; Rabbits; Serotonin; Thrombin | 1979 |
Biological properties of dialysable peptides derived from plasmin digestion of bovine fibrinogen preparations.
Topics: Adenosine Diphosphate; Animals; Cattle; Fibrinogen; Fibrinolysin; Molecular Weight; Myocardial Contraction; Peptides; Permeability; Platelet Adhesiveness | 1976 |
The ability of fibrinogen fragments to support ADP-induced platelet aggregation.
Topics: Adenosine Diphosphate; Agglutination Tests; Chemical Phenomena; Chemistry; Electrophoresis, Polyacrylamide Gel; Fibrinogen; Fibrinolysin; Humans; Peptides; Platelet Aggregation; Thrombin Time; Time Factors | 1979 |
Direct animal and indirect human evidence of altered platelet function in diabetics.
Topics: Adenosine Diphosphate; Adolescent; Adult; Aged; Animals; beta-Thromboglobulin; Blood Glucose; Blood Platelets; Blood Vessels; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Female; Fibrinogen; Humans; Insulin; Male; Middle Aged; Platelet Aggregation; Platelet Count; Prospective Studies; Prothrombin Time; Rabbits | 1979 |
Plasma protein regulation of platelet function and metabolism.
Topics: Adenosine Diphosphate; Blood Platelets; Blood Proteins; Calcium; Cyclic AMP; Fibrinogen; Humans; Immunoglobulin G; Oxygen Consumption; Platelet Aggregation; Serum Albumin | 1979 |
Effects of dimethyl sulfoxide on subunit proteins.
Topics: Adenosine Diphosphate; Animals; Blood Coagulation; Cattle; Dimethyl Sulfoxide; Enzyme Activation; Fibrinogen; Glucuronidase; Glutamate Dehydrogenase; Hirudins; Hydrogen-Ion Concentration; Kinetics; Liver; Protein Denaturation; Proteins; Temperature; Thrombin | 1975 |
Platelet interactions.
Topics: Adenosine Diphosphate; Blood Platelet Disorders; Blood Platelets; Catecholamines; Fatty Acids; Fibrinogen; Hemostasis; Humans; Peptide Hydrolases; Platelet Aggregation; Serotonin; von Willebrand Factor | 1978 |
Plasma cofactors of platelet function: correlation with diabetic retinopathy and hemoglobins Ala-c.
Topics: Adenosine Diphosphate; Adult; Blood Coagulation Factors; Blood Glucose; Blood Platelets; Diabetic Retinopathy; Factor VIII; Fibrinogen; Hemoglobin A; Hemoglobins; Humans; Platelet Aggregation; von Willebrand Factor | 1978 |
Potentiation of platelet aggregation by heat-precipitated plasma proteins.
Topics: Adenosine Diphosphate; Aspirin; Blood Proteins; Chemical Precipitation; Collagen; Epinephrine; Fibrinogen; Hemophilia A; Hot Temperature; Humans; Immunoglobulin G; In Vitro Techniques; Platelet Aggregation; von Willebrand Diseases | 1978 |
Active release of human platelet factor VIII-related antigen by adenosine diphosphate, collagen, and thrombin.
Topics: Adenosine Diphosphate; Antigens; Autoradiography; Blood Platelets; Collagen; Factor VIII; Fibrinogen; Hemostasis; Humans; Immunoelectrophoresis; Thrombin; Time Factors; von Willebrand Diseases | 1978 |
Relationship between phosphorylation of blood platelet proteins and secretion of platelet granule constituents. I. Effects of different aggregating agents.
Topics: Adenosine Diphosphate; Blood Platelets; Calcimycin; Collagen; Cytoplasmic Granules; Dimethyl Sulfoxide; Fibrinogen; Humans; Kinetics; Molecular Weight; Phosphoproteins; Platelet Aggregation; Serotonin; Thrombin | 1977 |
Effect of inorganic ions and plasmatic factors in ADP collagen, thrombin induced platelet aggregation.
Topics: Adenosine Diphosphate; Calcium; Collagen; Fibrinogen; Humans; Magnesium; Platelet Aggregation; Potassium; Thrombin | 1977 |
[Evaluation of platelet aggregation in essential hypertensive patients].
Topics: Adenosine Diphosphate; Adult; Age Factors; Blood Coagulation Tests; Female; Fibrinogen; Humans; Hypertension; Male; Middle Aged; Platelet Aggregation | 1977 |
Human platelets possess an inducible and saturable receptor specific for fibrinogen.
Topics: Adenosine Diphosphate; Blood Platelets; Fibrinogen; Humans; Kinetics; Platelet Aggregation; Receptors, Drug; Substrate Specificity | 1979 |
Inherited defective platelet aggregation with arachidonate as the main expression of a defective metabolism of arachidonic acid.
Topics: Adenosine Diphosphate; Adolescent; Adult; Aged; Arachidonic Acids; Bleeding Time; Blood Platelet Disorders; Child; Child, Preschool; Female; Fibrinogen; Humans; Male; Metabolism, Inborn Errors; Middle Aged; Pedigree; Platelet Aggregation; Thromboplastin | 1979 |
Comparison of fibrinogen association with normal and thrombasthenic platelets on exposure to ADP or chymotrypsin.
Topics: Adenosine Diphosphate; Blood Platelet Disorders; Blood Platelets; Chymotrypsin; Collagen; Fibrinogen; Humans; Iodine Radioisotopes; Platelet Aggregation; Serotonin; Thrombin | 1979 |
Heterogeneity in storage pool deficiency: studies on granule-bound substances in 18 patients including variants deficient in alpha-granules, platelet factor 4, beta-thromboglobulin, and platelet-derived growth factor.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adult; Blood Coagulation Disorders; Blood Coagulation Factors; Blood Platelets; Calcium; Cytoplasmic Granules; Female; Fibrinogen; Genetic Variation; Globulins; Growth Substances; Heparin; Humans; Male; Middle Aged; Mitochondria; Platelet Factor 4; Serotonin | 1979 |
[Alterations of plasma plasminogen and fibrinogen, serum fibrin degradation products and degree of ADP induced platelet aggregation in acute myocardial infarction (author's transl)].
Topics: Adenosine Diphosphate; Adult; Aged; Female; Fibrin Fibrinogen Degradation Products; Fibrinogen; Humans; Male; Middle Aged; Myocardial Infarction; Plasminogen; Platelet Aggregation | 1979 |
Exposure of platelet fibrinogen receptors by ADP and epinephrine.
Topics: Adenosine Diphosphate; Binding Sites; Blood Platelets; Calcium; Epinephrine; Fibrinogen; Hormones; Humans; Iodine Radioisotopes; Isotope Labeling; Magnesium; Platelet Aggregation; Purpura, Thrombocytopenic; Stimulation, Chemical | 1979 |
[Effect of iodinated roentgen contrast media on coagulation, fibrinolysis and platelets].
Topics: Adenosine Diphosphate; Blood Coagulation; Blood Platelets; Contrast Media; Fibrinogen; Fibrinolysis; Humans; In Vitro Techniques; Plasminogen | 1977 |
Fibrinogen and platelet aggregation. Role of the glycopeptidic part and of the fibrinopeptide B. Description of a new technique of fibrinoglycopeptide isolation.
Topics: Adenosine Diphosphate; Fibrin Fibrinogen Degradation Products; Fibrinogen; Fibrinopeptide B; Glycopeptides; Platelet Aggregation; Sialic Acids; Structure-Activity Relationship | 1978 |
Asialofibrinogen supports platelet aggregation and adhesion to glass.
Topics: Adenosine Diphosphate; Electrophoresis, Polyacrylamide Gel; Epinephrine; Fibrinogen; Humans; Molecular Weight; Neuraminidase; Platelet Adhesiveness; Platelet Aggregation; Sialic Acids | 1979 |
In vitro and in vivo functions of thrombin-treated platelets.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acids; Blood Platelets; Calcimycin; Cell Survival; Clot Retraction; Collagen; Fibrinogen; Platelet Adhesiveness; Platelet Aggregation; Rabbits; Serotonin; Thrombin; Thrombocytopenia | 1976 |
Platelet retention in glass bead columns: adhesion to glass and subsequent platelet-platelet interactions.
Topics: Adenosine Diphosphate; Blood Platelets; Edetic Acid; Fibrinogen; Glass; Humans; Platelet Adhesiveness; Thrombocytopenia; von Willebrand Factor | 1976 |
[Influence of acute exertion and physical training on platelet function of the coronary patient].
Topics: Adenosine Diphosphate; Aspirin; Blood Platelets; Coronary Disease; Fibrinogen; Humans; Lipids; Male; Middle Aged; Myocardial Infarction; Physical Exertion; Platelet Adhesiveness; Platelet Aggregation | 1976 |
Platelet function, blood coagulation and fibrinolysis in Behcet's syndrome.
Topics: Adenosine Diphosphate; Adult; Behcet Syndrome; Blood Coagulation; Blood Platelets; Factor VIII; Fibrinogen; Fibrinolysis; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Factor 4; Thrombosis | 1977 |
Hemostatic and platelet kinetic studies in dengue hemorrhagic fever.
Topics: Adenosine Diphosphate; Blood Cell Count; Blood Coagulation; Blood Coagulation Factors; Blood Platelets; Child; Dengue; Fibrin Fibrinogen Degradation Products; Fibrinogen; Hematocrit; Humans; Prothrombin Time; Thrombocytopenia; Thromboplastin | 1977 |
Dietary fatty acids and arterial thrombosis: effects and mechanism of action with special reference to linoleic acid.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acids; Blood Coagulation; Blood Platelets; Cholesterol; Collagen; Dietary Fats; Fatty Acids; Fibrinogen; Humans; Linoleic Acids; Platelet Aggregation; Prostaglandin Endoperoxides; Rats; Thrombin; Thrombosis | 1977 |
Fibrin-induced release of platelet serotonin.
Topics: Adenosine; Adenosine Diphosphate; Blood Platelets; Calcium; Fibrin; Fibrinogen; Hirudins; Humans; Platelet Adhesiveness; Platelet Aggregation; Prostaglandins E; Serotonin; Thrombin | 1976 |
On the susceptibility of human platelets to aggregation by concanavalin A and the effect of this lectin on their response to ADP.
Topics: Adenosine Diphosphate; Binding Sites; Calcium; Concanavalin A; Fibrinogen; Platelet Aggregation; Temperature; Trypsin | 1976 |
Platelet prostaglandin production and its implications.
Topics: Adenosine Diphosphate; Arachidonic Acids; Blood Platelets; Fibrinogen; Humans; Indomethacin; Organoids; Peroxides; Platelet Aggregation; Prostaglandins; Prostaglandins E | 1976 |
Reptilase clot retraction test. (Its cofactors and relation to other platelet functions).
Topics: Adenosine Diphosphate; Batroxobin; Blood Coagulation Disorders; Blood Platelets; Cations, Divalent; Clot Retraction; Collagen; Epinephrine; Fibrinogen; Humans; Peptide Hydrolases; Platelet Adhesiveness; Platelet Aggregation; Ristocetin; Sulfhydryl Compounds | 1975 |
Endothelial injury induced by thrombin or thrombi.
Topics: Adenosine Diphosphate; Animals; Aorta; Arteriosclerosis; Elastic Tissue; Endothelium; Fibrin; Fibrinogen; Male; Microscopy, Electron; Microscopy, Phase-Contrast; Platelet Aggregation; Rabbits; Sonication; Thrombin; Thrombosis; Tissue Extracts | 1975 |
Platelet adhesiveness and aggregation in congenital afibrinogenemia. An investigation of three patients with post-transfusion, cross-correction studies between two of them.
Topics: Adenosine Diphosphate; Afibrinogenemia; Agglutination; Child, Preschool; Collagen; Epinephrine; Fibrinogen; Filtration; Glass; Heparin; Humans; Infusions, Parenteral; Platelet Adhesiveness; Platelet Aggregation; Ristocetin; Thrombin | 1975 |
The coagulation mechanism in labor at term induced with prostaglandin F2 alpha.
Topics: Adenosine Diphosphate; Blood Coagulation; Blood Coagulation Tests; Blood Specimen Collection; Female; Fibrin; Fibrinogen; Gestational Age; Humans; Infusions, Parenteral; Labor, Induced; Platelet Aggregation; Postpartum Period; Pregnancy; Prostaglandins; Protamines; Prothrombin Time; Serum Globulins; Solubility; Thrombin; Thromboplastin; Time Factors | 1975 |
Physical changes in banked baboon blood.
Topics: Adenosine Diphosphate; Animals; Blood Coagulation Tests; Blood Preservation; Collagen; Erythrocyte Count; Fibrin; Fibrinogen; Hematocrit; Hemoglobins; Leukocyte Count; Papio; Platelet Aggregation; Prothrombin Time; Time Factors | 1975 |
Pathophysiology and mechanics of membrane lung performance deterioration.
Topics: Adenosine Diphosphate; Animals; Blood Cell Count; Blood Coagulation; Blood Flow Velocity; Blood Platelets; Blood Pressure; Carbon Dioxide; Cardiopulmonary Bypass; Cattle; Evaluation Studies as Topic; Fibrin; Fibrinogen; Hematocrit; Heparin; Microscopy, Electron, Scanning; Oxygen; Oxygenators, Membrane; Platelet Adhesiveness; Platelet Aggregation; Surface Properties; Time Factors | 1975 |
The hemostatic mechanism after open-heart surgery. II. Frequency of abnormal platelet functions during and after extracorporeal circulation.
Topics: Adenosine Diphosphate; Blood Cell Count; Blood Platelet Disorders; Blood Platelets; Blood Proteins; Cardiac Surgical Procedures; Collagen; Epinephrine; Extracorporeal Circulation; Fibrin; Fibrinogen; Hemorrhage; Humans; Platelet Adhesiveness; Platelet Aggregation; Platelet Factor 3; Postoperative Complications; Prospective Studies; Protamines; Time Factors | 1975 |
Effects of somatostatin on hemostasis in baboons.
Topics: Adenosine Diphosphate; Animals; Blood Cell Count; Blood Coagulation; Blood Coagulation Tests; Blood Platelets; Collagen; Epinephrine; Fibrinogen; Hemorrhage; Hemorrhagic Disorders; Hemosiderin; Hemostasis; Infusions, Parenteral; Lung; Lung Diseases; Male; Papio; Platelet Aggregation; Somatostatin; Thrombocytopenia | 1975 |
The effect of somatostatin on coagulation and platelet function in man.
Topics: Adenosine Diphosphate; Adult; Blood Cell Count; Blood Coagulation; Blood Coagulation Tests; Blood Glucose; Blood Platelets; Collagen; Diabetes Mellitus, Type 1; Drug Evaluation; Epinephrine; Female; Fibrin; Fibrinogen; Glucagon; Hematocrit; Humans; Infusions, Parenteral; Leukocyte Count; Male; Platelet Adhesiveness; Platelet Aggregation; Prothrombin Time; Serotonin; Somatostatin | 1975 |
No effect of an N-terminal fragment of human prothrombin on blood-platelet aggregation.
Topics: Adenosine Diphosphate; Calcium Chloride; Collagen; Fibrinogen; Humans; Peptide Chain Termination, Translational; Peptide Fragments; Platelet Adhesiveness; Platelet Aggregation; Prothrombin; Thrombin | 1975 |
Pregnancy, pre-eclampsia and disseminated intravascular coagulation.
Topics: Adenosine Diphosphate; Adult; Blood Coagulation Tests; Disseminated Intravascular Coagulation; Female; Fibrin; Fibrinogen; Humans; Pentosan Sulfuric Polyester; Platelet Aggregation; Platelet Factor 3; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Hematologic; Prospective Studies | 1975 |
Editorial: Intravascular factors in diabetic retinopathy.
Topics: Adenosine Diphosphate; Blood Platelets; Diabetic Retinopathy; Fibrinogen; Fibrinolysis; Platelet Aggregation | 1975 |
Adenine nucleotide metabolism during the aggregation of human platelets by bovine factor VIII.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Blood Cell Count; Blood Platelets; Cattle; Collagen; Factor VIII; Fibrinogen; Humans; Hypoxanthines; Inosine; Platelet Aggregation | 1975 |
Effects of ADP and ATP on bovine fibrinogen- and ristocetin-induced platelet aggregation in Glanzmann's thrombasthenia.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood Platelet Disorders; Cattle; Fibrinogen; Humans; Platelet Aggregation; Ristocetin | 1975 |
Effects of S-8527 (1, 1-bis (4'-(1"-carboxy-1"-methylpropoxy) phenyl) cyclohexane), a new hypolipidemic compound, on platelet aggregation, adhesiveness and blood coagulation in rats.
Topics: Adenosine Diphosphate; Animals; Blood Coagulation; Cholesterol; Clofibrate; Collagen; Cyclohexanes; Diet; Fibrinogen; Glycolates; Hypolipidemic Agents; Male; Phenoxyacetates; Platelet Adhesiveness; Platelet Aggregation; Rats; Sucrose; Thrombelastography; Triglycerides | 1975 |
[4 cases of congenital afibrinogenemia (author's transl)].
Topics: Adenosine Diphosphate; Afibrinogenemia; Cerebral Hemorrhage; Child; Child, Preschool; Citrates; Fibrinogen; Humans; Infant; Pedigree; Platelet Adhesiveness | 1975 |
Identification of a new congenital defect of platelet function characterized by severe impairment of platelet responses to adenosine diphosphate.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Blood Platelets; Calcium; Clot Retraction; Collagen; Cyclic AMP; Epinephrine; Fibrinogen; Hemorrhage; Humans; Indomethacin; Kinetics; Male; Middle Aged; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Prostaglandin Endoperoxides, Synthetic; Reference Values; Thrombin; Vasoconstrictor Agents; von Willebrand Factor | 1992 |
Effect of platelet agonists on the binding of platelet-activating factor to human platelets.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Blood Platelets; Fibrinogen; Humans; Iodine Radioisotopes; Platelet Activating Factor; Platelet Activation; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thrombin | 1992 |
A variant of Glanzmann's thrombasthenia which fails to express a GPIIb-IIIa related epitope that is recognized by a specific monoclonal antibody (C17).
Topics: Adenosine Diphosphate; Antibodies, Monoclonal; Arachidonic Acids; Collagen; Epitopes; Female; Fibrinogen; Humans; Middle Aged; Platelet Aggregation; Platelet Membrane Glycoproteins; Ristocetin; Thrombasthenia | 1992 |
Studies of fibrinogen binding to platelets by flow cytometry: an improved method for studies of platelet activation.
Topics: Adenosine Diphosphate; Animals; Antigen-Antibody Complex; Blood Platelets; Chickens; Evaluation Studies as Topic; Fibrinogen; Flow Cytometry; Fluorescein-5-isothiocyanate; Humans; Immunoglobulin G; In Vitro Techniques; Platelet Activation; Platelet Function Tests; Protein Binding | 1992 |
Pharmacological profile of G619, a new platelet aggregation inhibitor.
Topics: Adenosine Diphosphate; Animals; Benzamides; Calcium; Collagen; Dogs; Epinephrine; Fibrinogen; Humans; Male; Phenylacetates; Picolines; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Prostaglandin Endoperoxides, Synthetic; Rabbits; Rats; Rats, Sprague-Dawley; Receptors, Thromboxane; Shock, Septic; Sulfonamides; Thrombin; Thromboxane B2; Vasoconstriction | 1992 |
Interaction of nucleotide affinity analog 5'-p-fluorosulfonylbenzoyladenosine with platelet ADP receptor: aggregin.
Topics: Adenosine; Adenosine Diphosphate; Affinity Labels; Blood Platelets; Fibrinogen; Humans; Iodine Radioisotopes; Kinetics; Microscopy, Electron, Scanning; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptors, Purinergic; Tritium | 1992 |
Differences between platelet and microparticle glycoprotein IIb/IIIa.
Topics: Adenosine Diphosphate; Antibodies, Monoclonal; Antigens, Human Platelet; Blood Platelets; Calcimycin; Cations, Divalent; Edetic Acid; Fibrinogen; Humans; Platelet Aggregation; Platelet Membrane Glycoproteins; Protein Binding; Thrombin | 1992 |
Non-peptide fibrinogen receptor antagonists. 1. Discovery and design of exosite inhibitors.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Binding Sites; Endothelium, Vascular; Fibrinogen; Humans; Molecular Sequence Data; Molecular Structure; Oligopeptides; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Tirofiban; Tyrosine; Umbilical Veins | 1992 |
The human platelet as a reproducible and sensitive cell for the detection and assay of platelet-activating factor.
Topics: Adenosine; Adenosine Diphosphate; Adult; Biological Assay; Blood Platelets; Citric Acid; Female; Fibrinogen; Glucose; Humans; In Vitro Techniques; Male; Platelet Activating Factor; Platelet Aggregation; Reproducibility of Results; Serotonin | 1992 |
Platelet morphologic changes and fibrinogen receptor localization. Initial responses in ADP-activated human platelets.
Topics: Adenosine Diphosphate; Blood Platelets; Cell Aggregation; Cell Membrane; Fibrinogen; Humans; Intercellular Junctions; Microscopy, Electron, Scanning; Platelet Activation; Platelet Membrane Glycoproteins; Tissue Distribution | 1992 |
Differential effects of extra- and intracellular calcium chelation on human platelet function and glycoprotein IIb-IIIa complex stability.
Topics: Adenosine Diphosphate; Aminoquinolines; Blood Platelets; Calcium; Edetic Acid; Egtazic Acid; Extracellular Space; Fibrinogen; Humans; Immunoelectrophoresis, Two-Dimensional; Intracellular Fluid; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Serotonin | 1992 |
Effects of age, sex and the oral contraceptive on the platelet membrane fibrinogen binding site (glycoprotein IIb/IIIa).
Topics: Adenosine Diphosphate; Adult; Age Factors; Aged; Aged, 80 and over; Binding Sites; Contraceptives, Oral; Female; Fibrinogen; Humans; Male; Middle Aged; Platelet Membrane Glycoproteins; Sex Factors; Thrombin | 1992 |
Hypersensitivity to ADP of platelets from diabetic rats associated with enhanced fibrinogen binding.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Drug Resistance; Fibrinogen; In Vitro Techniques; Male; Platelet Aggregation; Platelet Membrane Glycoproteins; Rats; Rats, Inbred BB | 1992 |
Recognition of platelet-associated fibrinogen by polyclonal antibodies: correlation with platelet aggregation.
Topics: Adenosine Diphosphate; Alprostadil; Antibodies; Blood Platelets; Calcimycin; Chymotrypsin; Cytochalasin D; Fibrinogen; Humans; Immunoglobulin Fab Fragments; In Vitro Techniques; Kinetics; Platelet Aggregation; Platelet Membrane Glycoproteins; Thrombin | 1992 |
The effect of ticlopidine on canine platelets, fibrinogen, and antithrombin III activity.
Topics: Adenosine Diphosphate; Animals; Antithrombin III; Blood Platelets; Collagen; Dogs; Dose-Response Relationship, Drug; Female; Fibrinogen; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Serotonin; Ticlopidine | 1992 |
Spiking in cytosolic calcium concentration in single fibrinogen-bound fura-2-loaded human platelets.
Topics: Adenosine Diphosphate; Blood Platelets; Calcium; Cytosol; Egtazic Acid; Fibrinogen; Fura-2; Humans; Kinetics; Oligopeptides; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Signal Transduction; Time Factors | 1992 |
Characterization of the gamma chain platelet binding site on fibrinogen fragment D.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Binding Sites; Blood Platelets; Circular Dichroism; Electrophoresis, Polyacrylamide Gel; Fibrin Fibrinogen Degradation Products; Fibrinogen; Humans; In Vitro Techniques; Kinetics; Molecular Sequence Data; Peptides; Platelet Aggregation; Protein Conformation; Protein Denaturation | 1992 |
Discontinuous alterations of platelet structure and function by bound, ionizable verapamil.
Topics: Absorption; Adenosine Diphosphate; Blood Platelets; Cell Membrane; Fibrinogen; Humans; Hydrogen-Ion Concentration; Platelet Aggregation; Platelet Aggregation Inhibitors; Verapamil | 1992 |
Lack of stability of aggregates after thrombin-induced reaggregation of thrombin-degranulated platelets.
Topics: Adenosine Diphosphate; Blood Platelets; Fibrinogen; Humans; In Vitro Techniques; Microscopy, Electron; Platelet Aggregation; Thrombin | 1992 |
A defect of platelet aggregation associated with an abnormal distribution of glycoprotein IIb-IIIa complexes within the platelet: the cause of a lifelong bleeding disorder.
Topics: Adenosine Diphosphate; Adult; Antibodies, Monoclonal; Blood Platelets; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Epinephrine; Fibrinogen; Hemorrhage; Humans; In Vitro Techniques; Male; Microscopy, Electron; Platelet Aggregation; Platelet Membrane Glycoproteins | 1992 |
Mechanism of action of a potent antiplatelet peptide, triflavin from Trimeresurus flavoviridis snake venom.
Topics: Adenosine Diphosphate; Calcium; Crotalid Venoms; Fibrinogen; Humans; Iodine Radioisotopes; Peptides; Phosphatidylinositols; Platelet Aggregation Inhibitors; Protein Binding; Thromboxane A2; Thromboxane B2 | 1991 |
Interaction of heterologous fibrinogens with human platelet receptors.
Topics: Adenosine Diphosphate; Animals; Binding Sites; Blood Platelets; Cattle; Fibrinogen; Humans; Kinetics; Receptors, Cell Surface; Receptors, Peptide | 1991 |
Identification of a monoclonal antibody against platelet GPIIb that interacts with a calcium-binding site and induces aggregation.
Topics: Adenosine Diphosphate; Alprostadil; Amino Acid Sequence; Antibodies, Monoclonal; Antibody Specificity; Binding Sites; Blood Platelets; Calcium; Epitopes; Fibrinogen; Immunoglobulin Fab Fragments; Immunoglobulin G; Molecular Sequence Data; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptors, Fibronectin; Receptors, Immunologic; Receptors, Vitronectin; Serotonin | 1990 |
The peptide Glu-His-Ile-Pro-Ala binds fibrinogen and inhibits platelet aggregation and adhesion to fibrinogen and vitronectin.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Base Sequence; Binding Sites; Edetic Acid; Fibrinogen; Glycoproteins; Humans; In Vitro Techniques; Molecular Sequence Data; Oligopeptides; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Serotonin; Thrombin; Vitronectin | 1991 |
Platelet activation during preparation and storage of concentrates: detection by flow cytometry.
Topics: Adenosine Diphosphate; Blood Preservation; Cell Separation; Fibrinogen; Flow Cytometry; Humans; Membrane Glycoproteins; P-Selectin; Platelet Activation; Platelet Membrane Glycoproteins; Thrombin | 1991 |
Changes in the hemostatic system and compensatory responses during alimentary hyperlipidemia.
Topics: Adenosine Diphosphate; Animals; Blood Coagulation; Blood Platelets; Cholesterol; Fibrinogen; Fluorescence Polarization; Hyperlipidemias; Male; Membrane Fluidity; Membrane Lipids; Phospholipids; Platelet Aggregation; Rats; Rats, Inbred Strains; Thrombin; Triglycerides | 1991 |
Protein kinase C and cyclic AMP regulate reversible exposure of binding sites for fibrinogen on the glycoprotein IIB-IIIA complex of human platelets.
Topics: Adenosine Diphosphate; Binding Sites; Blood Platelets; Cyclic AMP; Epinephrine; Fibrinogen; Humans; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Signal Transduction; Temperature | 1991 |
A potent antiplatelet peptide, triflavin, from Trimeresurus flavoviridis snake venom.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Sequence; Amino Acids; Animals; Blood Platelets; Chromatography, Gel; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Collagen; Crotalid Venoms; Electrophoresis, Polyacrylamide Gel; Fibrinogen; Humans; Molecular Sequence Data; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Snakes | 1991 |
Halysin, an antiplatelet Arg-Gly-Asp-containing snake venom peptide, as fibrinogen receptor antagonist.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Sequence; Aminoquinolines; Antibodies, Monoclonal; Binding, Competitive; Blood Platelets; Calcium; Crotalid Venoms; Fibrinogen; Humans; Intercellular Signaling Peptides and Proteins; Kinetics; Molecular Sequence Data; Pancreatic Elastase; Peptides; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Thromboxane B2 | 1991 |
Hemostatic studies in racing standardbred horses with exercise-induced pulmonary hemorrhage. Hemostatic parameters at rest and after moderate exercise.
Topics: Adenosine Diphosphate; Animals; Antithrombin III; Collagen; Factor VIII; Fibrin; Fibrin Fibrinogen Degradation Products; Fibrinogen; Hematocrit; Hemorrhage; Hemostasis; Horse Diseases; Horses; Lung Diseases; Partial Thromboplastin Time; Physical Exertion; Platelet Activating Factor; Platelet Aggregation; Platelet Count; Prothrombin Time; Thrombin Time; von Willebrand Factor | 1991 |
Changes in parameters of the coagulation-fibrinolysis system and platelet function after OKY-046 administration to patients with ruptured aneurysm of the cerebral artery.
Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Blood Coagulation; Blood Platelets; Collagen; Female; Fibrinogen; Fibrinolysis; Humans; Intracranial Aneurysm; Male; Methacrylates; Middle Aged; Plasminogen Inactivators; Platelet Activating Factor; Rupture, Spontaneous; Thromboxane-A Synthase; Tissue Plasminogen Activator | 1991 |
Platelet activation by a synthetic hydrophobic polymer, polymethylmethacrylate.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Apyrase; Aspirin; Blood Platelets; Calcium; Chymotrypsin; Fibrinogen; Humans; Methylmethacrylates; Microscopy, Electron; Microscopy, Electron, Scanning; Microspheres; Molecular Sequence Data; Phosphorylation; Platelet Activation; Platelet Aggregation; Protein Kinase C; Serotonin | 1991 |
Inhibition of the thrombin-platelet reactions by DuP 714.
Topics: Adenosine Diphosphate; Arachidonic Acid; Blood Platelets; Boron Compounds; Collagen; Epinephrine; Fibrinogen; Hirudins; Humans; Kinetics; Oligopeptides; Platelet Aggregation; Platelet Membrane Glycoproteins; Thrombin | 1991 |
In vitro studies of the effect of buflomedil on platelet responsiveness.
Topics: Adenosine Diphosphate; Adrenergic alpha-Antagonists; Blood Platelets; Calcium; Collagen; Epinephrine; Fibrinogen; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Pyrrolidines; Yohimbine | 1990 |
Selective recognition of adhesive sites in surface-bound fibrinogen by glycoprotein IIb-IIIa on nonactivated platelets.
Topics: Adenosine Diphosphate; Binding Sites; Blood Platelets; Epinephrine; Fibrinogen; Humans; Kinetics; Microscopy, Electron, Scanning; Peptide Fragments; Platelet Adhesiveness; Platelet Membrane Glycoproteins | 1991 |
Mechanism of action of the antiplatelet peptide, arietin, from Bitis arietans venom.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Aminoquinolines; Animals; Blood Platelets; Calcium; Fibrinogen; Fluorescent Dyes; Intercellular Signaling Peptides and Proteins; Molecular Sequence Data; Oligopeptides; Pancreatic Elastase; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Snakes; Thrombin; Viper Venoms | 1991 |
Effect of fibrinogen concentration on the velocity of platelet aggregation.
Topics: Adenosine Diphosphate; Adult; Fibrinogen; Humans; In Vitro Techniques; Kinetics; Platelet Aggregation; Platelet Membrane Glycoproteins; Time Factors | 1991 |
Fish oil: a potent inhibitor of platelet adhesiveness.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Epinephrine; Fatty Acids; Female; Fibrinogen; Fish Oils; Humans; Kinetics; Male; Microscopy, Electron; Microscopy, Electron, Scanning; Middle Aged; Platelet Adhesiveness; Platelet Aggregation | 1990 |
Released adenosine diphosphate stabilizes thrombin-induced human platelet aggregates.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alprostadil; beta-Thromboglobulin; Chymotrypsin; Cytoplasmic Granules; Epinephrine; Fibrinogen; Humans; In Vitro Techniques; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Factor 4; Serotonin; Thrombin | 1990 |
Inositol phospholipid metabolism in human platelets stimulated by ADP.
Topics: Adenosine Diphosphate; Aspirin; Blood Platelets; Calcium; Fibrinogen; Humans; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Phosphatidic Acids; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphatidylinositols; Platelet Aggregation; Thromboxane A2; Type C Phospholipases | 1990 |
Inhibition of fibrinogen binding to human platelets by S-nitroso-N-acetylcysteine.
Topics: Acetylcysteine; Adenosine Diphosphate; Blood Platelets; Cyclic GMP; Fibrinogen; Humans; In Vitro Techniques; Kinetics; Platelet Aggregation; Platelet Aggregation Inhibitors | 1990 |
KRDS, a new peptide derived from human lactotransferrin, inhibits platelet aggregation and release reaction.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Antibodies, Monoclonal; Blood Platelets; Calcium; Fibrinogen; In Vitro Techniques; Lactoferrin; Molecular Sequence Data; Oligopeptides; Peptide Fragments; Phosphatidylinositols; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Protein Conformation; Serotonin; Signal Transduction; Tetradecanoylphorbol Acetate; Thrombin | 1990 |
Synergistic inhibition of platelet aggregation by fibrinogen-related peptides.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Drug Synergism; Fibrinogen; Humans; Molecular Sequence Data; Oligopeptides; Peptide Fragments; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors | 1990 |
Fibrinogen-containing membrane-associated structures arising at the surfaces of ADP-stimulated blood platelets.
Topics: Adenosine Diphosphate; Blood Platelets; Cell Membrane; Fibrinogen; Humans | 1990 |
Measurement of fibrinogen binding to platelets in whole blood by flow cytometry: a micromethod for the detection of platelet activation.
Topics: Adenosine Diphosphate; Antibodies; Antigen-Antibody Complex; Blood Platelets; Fibrinogen; Flow Cytometry; Humans; Platelet Activation; Thrombasthenia; Time Factors | 1990 |
Production and characterization of monoclonal antibodies against rat platelet GPIIb/IIIa.
Topics: Adenosine Diphosphate; Animals; Antibodies, Monoclonal; Enzyme-Linked Immunosorbent Assay; Fibrinogen; Hybridomas; Male; Mice; Mice, Inbred BALB C; Platelet Aggregation; Platelet Membrane Glycoproteins; Rats; Rats, Inbred Strains; Serotonin; Sodium Radioisotopes | 1990 |
Direct detection of activated platelets and platelet-derived microparticles in humans.
Topics: Adenosine Diphosphate; Antibodies, Monoclonal; Blood Platelets; Cardiopulmonary Bypass; Fibrinogen; Flow Cytometry; Hemorrhage; Humans; In Vitro Techniques; Platelet Activation; Platelet Membrane Glycoproteins | 1990 |
Localization of fibrinogen during ADP- or thrombin-induced aggregation of washed rabbit platelets.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Cytoplasmic Granules; Fibrinogen; Immunohistochemistry; In Vitro Techniques; Platelet Aggregation; Rabbits; Thrombin | 1990 |
The thienopyridine PCR 4099 selectively inhibits ADP-induced platelet aggregation and fibrinogen binding without modifying the membrane glycoprotein IIb-IIIa complex in rat and in man.
Topics: Adenosine Diphosphate; Animals; Clopidogrel; Female; Fibrinogen; Humans; Immunoelectrophoresis, Two-Dimensional; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Precipitin Tests; Rats; Rats, Inbred Strains; Ticlopidine | 1990 |
[Effect of cefaclor on guinea pig platelet aggregation in vitro].
Topics: Adenosine Diphosphate; Animals; Calcium; Cefaclor; Cephalexin; Fibrinogen; Guinea Pigs; In Vitro Techniques; Male; Membrane Glycoproteins; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombin | 1990 |
Inhibition of fibrin(ogen) binding to stimulated platelets by a monoclonal antibody specific for a conformational determinant of GPIIIa.
Topics: Adenosine Diphosphate; Amino Acids; Antibodies, Monoclonal; Antibody Specificity; Blood Platelets; Enzyme-Linked Immunosorbent Assay; Fibrin; Fibrinogen; Humans; Iodine Radioisotopes; Kinetics; Platelet Aggregation; Platelet Membrane Glycoproteins; Protein Binding; Protein Conformation; Spectrophotometry, Ultraviolet; Thrombin | 1990 |
Independent modulation of von Willebrand factor and fibrinogen binding to the platelet membrane glycoprotein IIb/IIIa complex as demonstrated by monoclonal antibody.
Topics: Adenosine Diphosphate; Antibodies, Monoclonal; Binding Sites; Blood Platelets; Calcium; Cell Membrane; Epitopes; Fibrinogen; Glycoproteins; Humans; Immunoglobulin Fab Fragments; Membrane Proteins; Platelet Membrane Glycoproteins; Temperature; Thrombin; von Willebrand Factor | 1985 |
High susceptibility to ADP-induced thrombus formation in mast cell-deficient W/Wv mice.
Topics: Adenosine Diphosphate; Animals; Blood Coagulation; Epitopes; Fibrinogen; Humans; Male; Mast Cells; Mesenteric Veins; Mice; Mice, Mutant Strains; Platelet Aggregation; Platelet Count; Thrombosis | 1985 |
Studies on the binding of an alloimmune and two murine monoclonal antibodies to the platelet glycoprotein IIb-IIIa complex receptor.
Topics: Adenosine Diphosphate; Animals; Antibodies, Monoclonal; Antigen-Antibody Complex; Blood Platelet Disorders; Blood Platelets; Chymotrypsin; Dinoprostone; Dogs; Epitopes; Epoprostenol; Fibrinogen; Glycoproteins; Humans; Immunoglobulin Allotypes; Iraq; Israel; Membrane Proteins; Platelet Aggregation; Platelet Membrane Glycoproteins; Prostaglandins E; Radioimmunoassay; Receptors, Cell Surface; Thrombasthenia | 1986 |
Changes in platelet beta-thromboglobulin, fibrinogen, albumin, 5-hydroxytryptamine, ATP, and ADP during and after surgery with extracorporeal circulation in man.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aged; Beta-Globulins; beta-Thromboglobulin; Blood Platelets; Coronary Artery Bypass; Extracorporeal Circulation; Fibrinogen; Humans; Middle Aged; Serotonin; Serum Albumin | 1986 |
Tissue plasminogen activator promotes platelet disaggregation in plasma.
Topics: Adenosine Diphosphate; alpha-2-Antiplasmin; Aspirin; Blood Platelets; Fibrin Fibrinogen Degradation Products; Fibrinogen; Humans; Kinetics; Platelet Aggregation; Platelet Membrane Glycoproteins; Tissue Plasminogen Activator | 1987 |
Occupancy of an adhesive glycoprotein receptor modulates expression of an antigenic site involved in cell adhesion.
Topics: Adenosine Diphosphate; Antibodies, Monoclonal; Blood Platelets; Calcium; Cations, Divalent; Edetic Acid; Enzyme-Linked Immunosorbent Assay; Epitopes; Fibrinogen; Humans; Oligopeptides; Peptides; Platelet Adhesiveness; Platelet Membrane Glycoproteins; Protein Conformation; Receptors, Immunologic; Receptors, Peptide | 1988 |
Platelet activation induced by a stable analogue of endoperoxides (U46619)
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Apyrase; beta-Thromboglobulin; Blood Platelets; Fibrinogen; Humans; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic | 1989 |
Epinephrine induces platelet fibrinogen receptor expression, fibrinogen binding, and aggregation in whole blood in the absence of other excitatory agonists.
Topics: Adenosine Diphosphate; Antibodies, Monoclonal; Blood Platelets; Epinephrine; Fibrinogen; Flow Cytometry; Humans; Platelet Activating Factor; Platelet Aggregation; Receptors, Cell Surface; Receptors, Peptide; Serotonin; Thrombin | 1989 |
Thrombin-induced platelet aggregation involves an indirect proteolytic cleavage of aggregin by calpain.
Topics: Adenosine; Adenosine Diphosphate; Affinity Labels; Antipain; Blood Platelets; Calpain; Electrophoresis, Polyacrylamide Gel; Fibrinogen; Humans; Leupeptins; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Protease Inhibitors; Thrombin | 1989 |
Inhibition of fibrinogen binding to human platelets by blockage of Na+/H+ exchange.
Topics: Adenosine Diphosphate; Amiloride; Aspirin; Blood Platelets; Carrier Proteins; Fibrinogen; Humans; In Vitro Techniques; Kinetics; Platelet Membrane Glycoproteins; Sodium-Hydrogen Exchangers | 1989 |
Immunocytochemical study of the binding of fibrinogen and thrombospondin to ADP- and thrombin-stimulated human platelets.
Topics: Adenosine Diphosphate; Antigen-Antibody Reactions; Blood Platelets; Cytoplasmic Granules; Fibrinogen; Glycoproteins; Gold; Humans; Staining and Labeling; Thrombin; Thrombospondins | 1985 |
In vivo method for the assessment of platelet accumulation.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Collagen; Drug Evaluation, Preclinical; Erythrocytes; Fibrinogen; Guinea Pigs; Indium Radioisotopes; Male; Microcomputers; Monitoring, Physiologic; Platelet Activating Factor; Platelet Aggregation; Radioisotope Dilution Technique | 1989 |
Modulation of an RGDS binding site on the platelet membrane glycoprotein IIb-IIIa complex.
Topics: Adenosine Diphosphate; Affinity Labels; Binding Sites; Blood Platelets; Calcium; Cations, Divalent; Electrophoresis, Polyacrylamide Gel; Fibrinogen; Magnesium; Oligopeptides; Photochemistry; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Thrombin | 1989 |
Exposure of fibrinogen-binding sites on stored platelets on stimulation by aggregating agents--an electron microscopic study.
Topics: Adenosine Diphosphate; Binding Sites; Blood Platelets; Blood Preservation; Epinephrine; Fibrinogen; Humans; Immunohistochemistry; In Vitro Techniques; Membrane Glycoproteins; Microscopy, Electron; Platelet Aggregation | 1989 |
Antiplatelet "hybrid" peptides analogous to receptor recognition domains on gamma and alpha chains of human fibrinogen.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Blood Platelets; Fibrinogen; Humans; Kinetics; Macromolecular Substances; Molecular Sequence Data; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Protein Multimerization | 1989 |
Association of fibrinogen with human platelets pretreated with chymotrypsin or aggregated with ADP or thrombin: an immunocytochemical study.
Topics: Adenosine Diphosphate; Blood Platelets; Chymotrypsin; Fibrinogen; Humans; Platelet Aggregation; Thrombin | 1989 |
Heterogeneity of fibrinogen receptor expression on platelets activated in normal plasma with ADP: analysis by flow cytometry.
Topics: Adenosine Diphosphate; Antigen-Antibody Reactions; Blood Platelets; Dose-Response Relationship, Drug; Fibrinogen; Flow Cytometry; Humans; Platelet Membrane Glycoproteins | 1989 |
Phosphatidylinositol 4,5-bisphosphate is selectively retained by platelet-fibrin clots formed by thrombin.
Topics: Adenosine Diphosphate; Animals; Blood Coagulation; Blood Platelets; Fibrin; Fibrinogen; Humans; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Phospholipids; Rabbits; Thrombin | 1987 |
Influence of beta-lactam antibiotics on platelets. II. In vitro effects of some beta-lactam antibiotics on the biochemical responses of rat platelets.
Topics: Adenosine Diphosphate; Animals; Anti-Bacterial Agents; beta-Lactams; Blood Platelets; Calcium; Fibrinogen; In Vitro Techniques; Microscopy, Electron, Scanning; Phosphatidylinositols; Phosphorylation; Platelet Aggregation; Rats; Surface Properties; Thrombin | 1987 |
Fibrin protofibril and fibrinogen binding to ADP-stimulated platelets: evidence for a common mechanism.
Topics: Adenosine Diphosphate; Antibodies, Monoclonal; Blood Platelets; Cell Membrane; Fibrin; Fibrinogen; Humans; Kinetics; Protein Binding; Receptors, Cell Surface; Receptors, Peptide | 1988 |
Aggregation-related association of lipid with the cytoskeleton of rabbit and human platelets prelabeled with [3H]palmitic acid. Similar effects of adenosine diphosphate- and thrombin-induced aggregation.
Topics: Actin Cytoskeleton; Adenosine Diphosphate; Animals; Blood Platelets; Calcium; Cyclic AMP; Cytoskeleton; Deoxyribonuclease I; Fibrinogen; Humans; In Vitro Techniques; Leupeptins; Lipid Metabolism; Microscopy, Electron; Palmitic Acid; Palmitic Acids; Platelet Aggregation; Platelet Membrane Glycoproteins; Rabbits; Thrombin | 1988 |
Immunocytochemical localization of fibrinogen on washed human platelets. Lack of requirement for fibrinogen during adenosine diphosphate-induced responses and enhanced fibrinogen binding in a medium with low calcium levels.
Topics: Adenosine Diphosphate; Blood Platelets; Calcium; Chymotrypsin; Fibrinogen; Humans; Immunohistochemistry; Platelet Aggregation; Receptors, Cell Surface | 1988 |
The role of fibrinogen A alpha chains in ADP-induced platelet aggregation in the presence of fibrinogen molecules containing gamma' chains.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Blood Platelets; Fibrinogen; Humans; Peptide Fragments; Platelet Aggregation; Protein Conformation; Receptors, Cell Surface; Receptors, Peptide | 1988 |
[Effect of thrombomodulin on specific thrombin functions: fibrinogen coagulation and thrombocyte aggregation].
Topics: Adenosine Diphosphate; Animals; Blood Coagulation; Dose-Response Relationship, Drug; Drug Interactions; Fibrinogen; Humans; Platelet Aggregation; Rabbits; Receptors, Cell Surface; Receptors, Thrombin; Thrombin | 1988 |
Platelet aggregation, haematocrit, and fibrinogen.
Topics: Adenosine Diphosphate; Erythrocytes; Fibrinogen; Hematocrit; Humans; Platelet Aggregation; Thrombosis | 1985 |
Impaired platelet aggregation and thromboxane generation in essential fatty acid-deficient rats.
Topics: Adenosine Diphosphate; alpha-Linolenic Acid; Animals; Blood Platelets; Dietary Fats; Fatty Acids; Fatty Acids, Essential; Fibrinogen; Fish Oils; Linoleic Acid; Linoleic Acids; Linolenic Acids; Liver; Male; Phospholipids; Platelet Aggregation; Rats; Rats, Inbred Strains; Safflower Oil; Thrombin; Thromboxane B2 | 1987 |
The secretory release reaction initiated by complement proteins C5b-9 occurs without platelet aggregation through glycoprotein IIb-IIIa.
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Complement Membrane Attack Complex; Complement System Proteins; Cytoplasmic Granules; Fibrinogen; Humans; Platelet Aggregation; Platelet Membrane Glycoproteins; Scattering, Radiation | 1989 |
Activation affects access to the platelet receptor for adhesive glycoproteins.
Topics: Adenosine Diphosphate; Antibodies, Monoclonal; Blood Platelets; Cell Membrane; Fibrinogen; Glycoproteins; Immunoglobulin Fab Fragments; Macromolecular Substances; Membrane Proteins; Molecular Weight; Platelet Adhesiveness; Platelet Membrane Glycoproteins; Protein Conformation; Structure-Activity Relationship | 1986 |
Identification of two distinct regions within the binding sites for fibrinogen and fibronectin on the IIb-IIIa human platelet membrane glycoprotein complex by monoclonal antibodies P2 and P4.
Topics: Adenosine Diphosphate; Antibodies, Monoclonal; Binding, Competitive; Blood Platelets; Fibrinogen; Fibronectins; Humans; Immunoelectrophoresis, Two-Dimensional; Platelet Aggregation; Platelet Membrane Glycoproteins; Radioimmunoassay; Receptors, Fibronectin; Receptors, Immunologic; Thrombin | 1986 |
Fibrinopeptide A and platelet factor levels in unstable angina pectoris.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Angina Pectoris; Angina, Unstable; beta-Thromboglobulin; Coronary Angiography; Fibrinogen; Fibrinopeptide A; Heart Ventricles; Humans; Physical Exertion; Platelet Aggregation; Platelet Factor 4; Thromboxane B2; Time Factors | 1987 |
Increased binding of fibrinogen to platelets in diabetes: the role of prostaglandins and thromboxane.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adenosine Triphosphate; Adolescent; Adult; Antibodies, Monoclonal; Binding Sites, Antibody; Binding, Competitive; Blood Platelets; Collagen; Diabetes Mellitus, Type 1; Female; Fibrinogen; Humans; In Vitro Techniques; Male; Platelet Aggregation; Platelet Membrane Glycoproteins; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Receptors, Cell Surface; Thromboxane B2 | 1985 |
Hypoalbuminemia-related platelet hypersensitivity in two dogs with nephrotic syndrome.
Topics: Adenosine Diphosphate; Animals; Antithrombin III; Cyclic AMP; Dogs; Fibrinogen; Nephrotic Syndrome; Platelet Aggregation; Serum Albumin | 1985 |
The tetrapeptide analogue of the cell attachment site of fibronectin inhibits platelet aggregation and fibrinogen binding to activated platelets.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Blood Platelets; Fibrinogen; Fibronectins; Humans; Kinetics; Oligopeptides; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Serotonin | 1985 |
Epinephrine-induced aggregation of rabbit platelets refractory to ADP.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Calcium; Epinephrine; Fibrinogen; Kinetics; Platelet Aggregation; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface | 1985 |
Studies on platelets of patients with inherited platelet disorders suggest that collagen-induced fibrinogen binding to membrane receptors requires secreted ADP but not released alpha-granule proteins.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Blood Coagulation Disorders; Blood Platelets; Chediak-Higashi Syndrome; Collagen; Cytoplasmic Granules; Fibrinogen; Glycoproteins; Humans; Membrane Proteins; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Serotonin | 1985 |
von Willebrand factor interaction with the glycoprotein IIb/IIa complex. Its role in platelet function as demonstrated in patients with congenital afibrinogenemia.
Topics: Adenosine Diphosphate; Afibrinogenemia; Bleeding Time; Blood Platelets; Collagen; Deamino Arginine Vasopressin; Fibrinogen; Humans; Immunoglobulin Fab Fragments; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptors, Cell Surface; von Willebrand Factor | 1986 |
Increased binding to ADP-stimulated platelets and aggregation effect of the dysfibrinogen Oslo I as compared with normal fibrinogen.
Topics: Adenosine Diphosphate; Blood Platelets; Cell Separation; Fibrinogen; Fibrinogens, Abnormal; Humans; Iodine Radioisotopes; Kinetics; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptors, Cell Surface | 1986 |
Modification of platelet functions by monobromobimane, a fluorescent thiol group label.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Clot Retraction; Collagen; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Epinephrine; Fibrinogen; Fluorescent Dyes; Humans; Platelet Aggregation; Quaternary Ammonium Compounds; Sulfhydryl Compounds; Thrombin; Tritium | 1986 |
Inhibition of platelet function with synthetic peptides designed to be high-affinity antagonists of fibrinogen binding to platelets.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Arginine; Binding, Competitive; Blood Platelets; Fibrinogen; Humans; Oligopeptides; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Structure-Activity Relationship; Thrombin | 1986 |
Identification of receptors for fibrinogen and von Willebrand factor mediating aggregation in guinea pig platelets.
Topics: Adenosine Diphosphate; Animals; Antibodies, Monoclonal; Blood Platelets; Fibrinogen; Guinea Pigs; In Vitro Techniques; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Ristocetin; von Willebrand Factor | 1986 |
Platelet dysfunction in uremia. II. Correction by arachidonic acid of the impaired exposure of fibrinogen receptors by adenosine diphosphate or collagen.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Binding, Competitive; Blood Platelets; Collagen; Female; Fibrinogen; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Uremia | 1986 |
Fibrinogen mitogenic effect on hemopoietic cell lines: control via receptor modulation.
Topics: Adenosine Diphosphate; Binding Sites; Binding, Competitive; Blood Platelets; Bucladesine; Cell Line; Edetic Acid; Fibrinogen; Hematopoietic Stem Cells; Humans; Mitogens; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Thrombin | 1986 |
Synergistic action of two murine monoclonal antibodies that inhibit ADP-induced platelet aggregation without blocking fibrinogen binding.
Topics: Adenosine Diphosphate; Animals; Antibodies, Monoclonal; Blood Platelets; Drug Synergism; Fibrinogen; Glycoproteins; Humans; In Vitro Techniques; Platelet Aggregation; Receptors, Cell Surface | 1987 |
Analysis of distribution of receptors among platelets by flow cytometry.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Cattle; Dose-Response Relationship, Drug; Fibrinogen; Flow Cytometry; Fluorescein-5-isothiocyanate; Fluoresceins; Protein Binding; Receptors, Cell Surface; Receptors, Purinergic; Serotonin; Thiocyanates | 1987 |
Arginyl-glycyl-aspartic acid sequences and fibrinogen binding to platelets.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Blood Platelets; Cell Adhesion; Fibrinogen; Humans; Oligopeptides; Platelet Aggregation; Protein Binding; Receptors, Cell Surface; Serine | 1987 |
Inhibition of von Willebrand factor binding to platelets by two recognition site peptides: the pentadecapeptide of the carboxy terminus of the fibrinogen gamma chain and the tetrapeptide arg-gly-asp-ser.
Topics: Adenosine Diphosphate; Binding Sites; Blood Platelets; Dose-Response Relationship, Drug; Fibrinogen; Humans; Oligopeptides; Peptide Fragments; Platelet Aggregation; Platelet Membrane Glycoproteins; Protein Binding; Protein Conformation; Receptors, Cell Surface; Thrombin; von Willebrand Factor | 1987 |
Effect of fibrinopeptides A and B on human and rat platelet aggregation in vitro.
Topics: Adenosine Diphosphate; Animals; Collagen; Epoprostenol; Fibrinogen; Fibrinopeptide A; Fibrinopeptide B; Humans; In Vitro Techniques; Male; Platelet Aggregation; Prostaglandin D2; Rats; Rats, Inbred Strains | 1988 |
Release of prostacyclin after erythrocyte adhesion to cultured vascular endothelium.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Adenosine Triphosphate; Adult; Anemia, Sickle Cell; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Blood Proteins; Blood Vessels; Cell Adhesion; Cells, Cultured; Cyclooxygenase Inhibitors; Diabetes Mellitus; Endothelium; Epoprostenol; Erythrocytes; Fibrinogen; Flurbiprofen; Humans; Leukocytes; Middle Aged; Plasma; Prostaglandins F; Thromboxane B2 | 1986 |
Platelet storage pool deficiency in pigs.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood Platelet Disorders; Blood Platelets; Carbon Radioisotopes; Disease Models, Animal; Factor VIII; Fibrinogen; Infusions, Parenteral; Platelet Aggregation; Platelet Storage Pool Deficiency; Serotonin; Swine | 1986 |
Platelet-activating factor (PAF-acether) induces high- and low-affinity binding of fibrinogen to human platelets via independent mechanisms.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Fibrinogen; Humans; Indomethacin; Kinetics; Macromolecular Substances; Platelet Activating Factor; Prostaglandin Endoperoxides; Protein Binding; Thromboxanes | 1986 |
Fibrinogen-independent aggregation and deaggregation of human platelets: studies in two afibrinogenemic patients.
Topics: Adenosine Diphosphate; Adolescent; Adult; Afibrinogenemia; Antibodies; Chymotrypsin; Edetic Acid; Female; Fibrinogen; Hirudins; Humans; Immunoglobulin Fab Fragments; Platelet Aggregation; Platelet Membrane Glycoproteins; Thrombin | 1987 |
Mechanisms of platelet aggregation by viridans group streptococci.
Topics: Adenosine Diphosphate; Blood Platelets; Endocarditis, Bacterial; Fibrinogen; Humans; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Streptococcus; Streptococcus sanguis; Time Factors | 1987 |
Sex-related differences in platelet aggregation in native whole blood.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Collagen; Female; Fibrinogen; Humans; Male; Platelet Aggregation; Sex Factors; Thrombin | 1987 |
Glycosylation of human fibrinogen and fibrin in vitro. Its consequences on the properties of fibrin(ogen).
Topics: Adenosine Diphosphate; Blood Coagulation; Factor XIII; Fibrin; Fibrinogen; Fibrinolysis; Glucose; Glycosylation; Humans; Kinetics; Lysine; Platelet Aggregation | 1987 |
Platelet thromboxane formation capacity after ethanol withdrawal in chronic alcoholics.
Topics: Adenosine Diphosphate; Adult; Alcoholism; Arachidonic Acid; Arachidonic Acids; Bleeding Time; Blood Platelets; Collagen; Ethanol; Female; Fibrinogen; Humans; Liver Diseases, Alcoholic; Male; Middle Aged; Platelet Aggregation; Platelet Count; Serum Albumin; Substance Withdrawal Syndrome; Thromboxane B2 | 1988 |
Effects of plasmin on rabbit platelets.
Topics: Adenosine Diphosphate; Alprostadil; Animals; Blood Platelets; Fibrinogen; Fibrinolysin; In Vitro Techniques; Platelet Aggregation; Prostaglandins E; Rabbits; Serotonin; Thrombin | 1985 |
Examination of irreversible platelet-fibrinogen interactions.
Topics: Adenosine Diphosphate; Blood Platelets; Cytochalasins; Cytoskeleton; Dimethyl Sulfoxide; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Fibrinogen; Fibrinolysin; Humans; Octoxynol; Polyethylene Glycols | 1985 |
Blood coagulation studies in guineapigs (Cavia porcellus).
Topics: Adenosine Diphosphate; Animals; Blood Coagulation; Female; Fibrinogen; Fibrinolysis; Guinea Pigs; Humans; Male; Partial Thromboplastin Time; Platelet Aggregation; Prothrombin Time; Reference Values; Serum Globulins; Thrombelastography; Thrombin Time | 1988 |
Fibrinogen association with human monocytes: evidence for constitutive expression of fibrinogen receptors and for involvement of Mac-1 (CD18, CR3) in the binding.
Topics: Adenosine Diphosphate; Antibodies, Monoclonal; Calcium; Fibrinogen; Humans; In Vitro Techniques; Kinetics; Lipopolysaccharides; Luminescent Measurements; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Platelet Membrane Glycoproteins; Polymyxin B; Radioligand Assay; Thrombin | 1988 |
Plasminogen interactions with platelets in plasma.
Topics: Adenosine Diphosphate; Aminocaproates; Binding Sites; Blood Platelets; Cell Adhesion; Fibrinogen; Flow Cytometry; Humans; In Vitro Techniques; Oligopeptides; Plasminogen; Platelet Aggregation; Protein Binding | 1988 |
Allosteric equilibria in the binding of fibrinogen to platelets.
Topics: Adenosine Diphosphate; Allosteric Regulation; Blood Platelets; Fibrinogen; Humans; Kinetics; Protein Binding | 1988 |
Role of ADP in platelet aggregation and fibrinogen binding induced by prostaglandin endoperoxides: studies in a patient with a selective defect of ADP-induced platelet aggregation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Antigens, Differentiation; Binding, Competitive; Fibrinogen; Humans; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic | 1988 |
Heterogeneity of fibrinogen receptor expression on human platelets activated by ADP in native plasma.
Topics: Adenosine Diphosphate; Blood Platelets; Fibrinogen; Humans; Platelet Membrane Glycoproteins | 1988 |
Plasma components are required for platelet activation by the toxin of Loxosceles reclusa.
Topics: Adenosine Diphosphate; Arthropod Venoms; Blood Platelets; Calcium; Fibrinogen; Humans; In Vitro Techniques; Plasma; Platelet Activating Factor; Platelet Aggregation; Prostaglandins; Serotonin; Spider Venoms | 1988 |
Complement proteins C5b-9 initiate secretion of platelet storage granules without increased binding of fibrinogen or von Willebrand factor to newly expressed cell surface GPIIb-IIIa.
Topics: Adenosine Diphosphate; Antibodies, Monoclonal; Binding Sites, Antibody; Binding, Competitive; Blood Platelets; Chromatography, Gel; Complement Membrane Attack Complex; Complement System Proteins; Cytoplasmic Granules; Feedback; Fibrinogen; Oligopeptides; Platelet Membrane Glycoproteins; Protein Conformation; Thrombin; von Willebrand Factor | 1988 |
KRDS--a tetrapeptide derived from lactotransferrin--inhibits binding of monoclonal antibody against glycoprotein IIb-IIIa on ADP-stimulated platelets and megakaryocytes.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Antibodies, Monoclonal; Binding Sites, Antibody; Binding, Competitive; Caseins; Fibrinogen; Humans; Immunoenzyme Techniques; Lactoferrin; Lactoglobulins; Megakaryocytes; Molecular Sequence Data; Oligopeptides; Peptide Fragments; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins | 1988 |
Detection of activated platelets in whole blood using activation-dependent monoclonal antibodies and flow cytometry.
Topics: Adenosine Diphosphate; Antibodies, Monoclonal; Antibody Specificity; Antigens, Surface; Binding Sites, Antibody; Binding, Competitive; Biotin; Blood Platelets; Cell Separation; Chromatography, Gel; Fibrinogen; Flow Cytometry; Fluorescent Antibody Technique; Platelet Aggregation; Platelet Membrane Glycoproteins | 1987 |
Prostacyclin immobilized albuminated surfaces.
Topics: Adenosine Diphosphate; Adsorption; Albumins; Animals; Biocompatible Materials; Cattle; Electrolytes; Epoprostenol; Fibrinogen; Kinetics; Platelet Adhesiveness; Polyurethanes; Prostaglandins, Synthetic; Surface Properties; Thrombin; Urea | 1987 |
Effects of the cell adhesion peptide, Arg-Gly-Asp-Ser, on responses of washed platelets from humans, rabbits, and rats.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Fibrinogen; Humans; Oligopeptides; Platelet Aggregation; Rabbits; Rats; Receptors, Purinergic; Species Specificity | 1988 |
Expression of fibrinogen on the surface of ADP-stimulated platelets: comparison of human and rabbit platelets.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Cell Membrane; Fibrinogen; Humans; In Vitro Techniques; Platelet Aggregation; Rabbits; Species Specificity | 1988 |
Effect of PCR 4099 on ADP-induced calcium movements and phosphatidic acid production in rat platelets.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Calcium; Clopidogrel; Fibrinogen; In Vitro Techniques; Phosphatidic Acids; Platelet Aggregation; Rats; Ticlopidine; Type C Phospholipases | 1988 |
Effect of GPIIb-IIIa complex ligands on calcium ion movement and cytoskeleton organization in activated platelets.
Topics: Adenosine Diphosphate; Blood Platelets; Calcium; Cytoplasm; Cytoskeleton; Fibrinogen; Humans; Platelet Aggregation; Platelet Membrane Glycoproteins; Thrombin | 1988 |
Interaction of fibrinogen with its platelet receptor. Differential effects of alpha and gamma chain fibrinogen peptides on the glycoprotein IIb-IIIa complex.
Topics: Adenosine Diphosphate; Antibodies, Monoclonal; Blood Platelets; Fibrinogen; Humans; Kinetics; Macromolecular Substances; Platelet Membrane Glycoproteins; Protein Binding | 1988 |
von Willebrand factor can substitute for plasma fibrinogen in ADP-induced platelet aggregation.
Topics: Adenosine Diphosphate; Blood Platelets; Fibrinogen; Humans; In Vitro Techniques; Platelet Aggregation; Platelet Membrane Glycoproteins; Thrombin; von Willebrand Factor | 1986 |
Effect of calcium ion concentration on the ability of fibrinogen and von Willebrand factor to support the ADP-induced aggregation of human platelets.
Topics: Adenosine Diphosphate; Calcium; Culture Media; Fibrinogen; Humans; Osmolar Concentration; Platelet Aggregation; von Willebrand Factor | 1987 |
Effects of diltiazem hydrochloride on cardiovascular response, platelet aggregation and coagulating activity during exercise testing in systemic hypertension.
Topics: Adenosine Diphosphate; Adult; Antithrombin III; Benzazepines; Blood Coagulation; Cardiovascular System; Diltiazem; Exercise Test; Female; Fibrinogen; Heart Rate; Humans; Hypertension; Male; Middle Aged; Partial Thromboplastin Time; Platelet Aggregation; Prothrombin Time; Renin | 1986 |
The platelet fibrinogen receptor: an immunogold-surface replica study of agonist-induced ligand binding and receptor clustering.
Topics: Adenosine Diphosphate; Blood Platelets; Cell Membrane; Fibrinogen; Humans; Microscopy, Electron; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptor Aggregation; Thrombin | 1987 |
Platelet fibrinogen binding in familial hypercholesterolemia.
Topics: Adenosine Diphosphate; Adolescent; Adult; Blood Platelets; Child; Female; Fibrinogen; Humans; Hyperlipoproteinemia Type II; Male; Platelet Aggregation; Platelet Membrane Glycoproteins; Protein Binding; Thromboxanes; Ticlopidine | 1987 |
Fibrinogen interaction with platelets of diabetic subjects.
Topics: Adenosine Diphosphate; Adult; Aged; Alprostadil; Antibodies, Monoclonal; Binding Sites; Blood Platelets; Chymotrypsin; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Fibrinogen; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Membrane Glycoproteins; Reference Values | 1987 |
ADP-induced platelet aggregation depends on the conformation or availability of the terminal gamma chain sequence of fibrinogen. Study of the reactivity of fibrinogen Paris 1.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Biological Availability; Cyanogen Bromide; Fibrinogen; Fibrinogens, Abnormal; Humans; Molecular Conformation; Peptides; Platelet Aggregation | 1987 |
Platelet function and intraplatelet von Willebrand factor antigen and fibrinogen in myelodysplastic syndromes.
Topics: Adenosine Diphosphate; Aged; Antigens; Bleeding Time; Blood Platelets; Cytoplasm; Epinephrine; Female; Fibrinogen; Humans; Male; Middle Aged; Myelodysplastic Syndromes; Platelet Adhesiveness; Platelet Aggregation; Platelet Count; von Willebrand Factor | 1987 |
Adhesion of human breast cancer cell line MCF-7 to human vascular endothelial cells in culture. Enhancement by activated platelets.
Topics: Adenosine Diphosphate; Breast Neoplasms; Cell Adhesion; Cell Cycle; Cells, Cultured; Endothelium, Vascular; Epinephrine; Extracellular Matrix; Female; Fibrinogen; Heparin; Hirudins; Humans; Microscopy, Electron; Microscopy, Electron, Scanning; Oligopeptides; Platelet Aggregation; Thrombin | 1987 |
Trigramin. A low molecular weight peptide inhibiting fibrinogen interaction with platelet receptors expressed on glycoprotein IIb-IIIa complex.
Topics: Adenosine Diphosphate; Blood Platelets; Crotalid Venoms; Fibrinogen; Humans; Intercellular Signaling Peptides and Proteins; Kinetics; Peptides; Phospholipases A; Platelet Aggregation; Platelet Membrane Glycoproteins; Serotonin; Thrombin | 1987 |
Interactions of human blood platelets with three circulating plasma fibrinogens of different molecular weights.
Topics: Adenosine Diphosphate; Binding, Competitive; Blood Platelets; Fibrinogen; Humans; Molecular Weight; Platelet Aggregation; Stimulation, Chemical | 1987 |
Platelet aggregation by fibrinogen polymers crosslinked across the E domain.
Topics: Adenosine Diphosphate; Calcium; Cross-Linking Reagents; Cytoplasm; Fibrin Fibrinogen Degradation Products; Fibrinogen; Humans; Phosphocreatine; Platelet Aggregation; Polymers; Serotonin | 1986 |
Analogy between fibrinogen and casein. Effect of an undecapeptide isolated from kappa-casein on platelet function.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Animals; Blood Platelets; Caseins; Cattle; Fibrinogen; Humans; Oligopeptides; Platelet Aggregation | 1986 |
Hemostasis following inoculation and during spreading of colon carcinoma in the rat.
Topics: Adenosine Diphosphate; Animals; Blood Coagulation; Collagen; Colonic Neoplasms; Fibrinogen; Hematocrit; Hemoglobins; Hemostasis; Neoplasm Metastasis; Partial Thromboplastin Time; Platelet Aggregation; Platelet Count; Rats; Rats, Inbred Strains | 1986 |
Binding of fibrinogen to human monocytes.
Topics: Adenosine Diphosphate; Electrophoresis, Polyacrylamide Gel; Fibrinogen; Humans; Kinetics; Methionine; Microscopy, Electron; Molecular Weight; Monocytes; Platelet Membrane Glycoproteins; Thrombin | 1986 |
Mechanism of human platelet activation by endotoxic glycolipid-bearing mutant Re595 of Salmonella minnesota.
Topics: Adenosine Diphosphate; Apyrase; Bacterial Toxins; Blood Platelets; Cations, Divalent; Endotoxins; Fibrinogen; Glycolipids; Humans; Lipid A; Lipopolysaccharides; Mutation; Oligosaccharides; Phosphoproteins; Phosphorylation; Platelet Aggregation; Prostaglandins; Salmonella; Serotonin; Structure-Activity Relationship | 1986 |
Crossed immunoelectrophoresis of human platelet membranes. Effect of charge on association and dissociation of the glycoprotein GPIIb-GPIIIa membrane complex.
Topics: Adenosine Diphosphate; Blood Platelets; Calcium; Cell Membrane; Fibrinogen; Humans; Immunoelectrophoresis, Two-Dimensional; Neuraminidase; Platelet Membrane Glycoproteins; Trypsin | 1986 |
Thromboxane generation by human monocytes enhances platelet function.
Topics: Adenosine Diphosphate; Blood Platelets; Fibrinogen; Humans; Indomethacin; Monocytes; Platelet Aggregation; Thromboxanes | 1986 |
Competitions between fibrinogen with its degradation products for interactions with the platelet-fibrinogen receptor.
Topics: Adenosine Diphosphate; Binding, Competitive; Blood Platelets; Fibrin Fibrinogen Degradation Products; Fibrinogen; Humans; Iodine Radioisotopes; Platelet Aggregation; Platelet Membrane Glycoproteins; Protein Binding | 1986 |
[Influence of certain molecules on the partial renewal of platelet phospholipids in Aymaras, Quechuas and European populations].
Topics: Adenosine Diphosphate; Adult; Altitude; Blood Platelets; Bolivia; Female; Fibrinogen; France; Humans; Indians, South American; Male; Phospholipids; Platelet Aggregation | 1985 |
Alterations of blood platelet function induced by neutral proteases from human leukocytes.
Topics: Adenosine Diphosphate; Blood Platelets; Chymotrypsin; Collagen; Fibrinogen; Humans; In Vitro Techniques; Leukocytes; Pancreatic Elastase; Peptide Hydrolases; Platelet Aggregation; Ristocetin | 1985 |
Platelet aggregation occurs in congenital afibrinogenaemia despite the absence of fibrinogen or its fragments in plasma and platelets, as demonstrated by immunoenzymology.
Topics: Adenosine Diphosphate; Afibrinogenemia; Blood Platelets; Child, Preschool; Collagen; Fibrin Fibrinogen Degradation Products; Fibrinogen; Humans; Immunoenzyme Techniques; Male; Platelet Aggregation; Thrombin | 1985 |
Epidemiological characteristics of platelet aggregability.
Topics: Adenosine Diphosphate; Adult; Age Factors; Aged; Alcohol Drinking; Black or African American; Coronary Disease; Female; Fibrinogen; Humans; Male; Middle Aged; Platelet Aggregation; Smoking | 1985 |
Action mechanism of the platelet aggregation inducer and inhibitor from Echis carinatus snake venom.
Topics: Adenosine Diphosphate; Alprostadil; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Chymotrypsin; Collagen; Fibrinogen; Heparin; Hirudins; Platelet Activating Factor; Platelet Aggregation; Prostaglandins E; Rabbits; Thrombin; Viper Venoms | 1985 |
Comparison of the interactions of fibrinogen and soluble fibrin with washed rabbit platelets stimulated with ADP.
Topics: Adenosine Diphosphate; Alprostadil; Animals; Apyrase; Blood Platelets; Creatine Kinase; Edetic Acid; Fibrin; Fibrinogen; Oligopeptides; Phosphocreatine; Platelet Aggregation; Prostaglandins E; Rabbits | 1985 |
Fibrinogen binding to human blood platelets: effect of gamma chain carboxyterminal structure and length.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Aspirin; Blood Platelets; Fibrinogen; Humans; Macromolecular Substances; Platelet Aggregation; Protein Binding; Structure-Activity Relationship; Time Factors | 1986 |
Characteristics of collagen-induced fibrinogen binding to human platelets.
Topics: Adenosine Diphosphate; Blood Platelets; Collagen; Fibrinogen; Humans; Platelet Aggregation; Serotonin; Time Factors | 1985 |
Measurement of fibrinogen concentrations in suspensions of washed rabbit and human platelets by radioimmunoassays.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Fibrinogen; Humans; In Vitro Techniques; Platelet Aggregation; Rabbits; Radioimmunoassay; Thrombin | 1985 |
Fibrinogen fragment D is a recognition site for release-related platelet aggregation.
Topics: Adenosine Diphosphate; Binding Sites; Blood Platelets; Fibrin Fibrinogen Degradation Products; Fibrinogen; Glycoproteins; Humans; In Vitro Techniques; Platelet Aggregation; Thrombin; Thrombospondins | 1985 |
Evidence that a collagen derived octapeptide inhibits fibrinogen binding to platelets stimulated by collagen and not by ADP.
Topics: Adenosine Diphosphate; Blood Platelets; Collagen; Fibrinogen; Humans; Platelet Aggregation; Serotonin | 1985 |
Fibronectin binding to thrombin-stimulated platelets: evidence for fibrin(ogen) independent and dependent pathways.
Topics: Adenosine Diphosphate; Binding, Competitive; Blood Platelets; Cations, Divalent; Fibrin; Fibrinogen; Fibronectins; Humans; In Vitro Techniques; Molecular Weight; Thrombin | 1985 |
The effect of physiological levels of fibrinogen on platelet aggregation.
Topics: Adenosine Diphosphate; Adult; Afibrinogenemia; Fibrinogen; Humans; In Vitro Techniques; Platelet Aggregation | 1985 |
A study of the kinetics and mechanism of ADP-triggered platelet aggregation.
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Fibrinogen; Humans; In Vitro Techniques; Kinetics; Light; Microspheres; Models, Biological; Platelet Aggregation; Scattering, Radiation | 1985 |
Human platelet fibrinogen: purification and hemostatic properties.
Topics: Adenosine Diphosphate; Binding, Competitive; Blood Coagulation; Blood Platelets; Blood Proteins; Cytoplasmic Granules; Electrophoresis, Polyacrylamide Gel; Fibrinogen; Hemostasis; Humans; Platelet Aggregation; Sodium Dodecyl Sulfate | 1985 |
Fibrinogen distribution on surfaces and in organelles of ADP stimulated human blood platelets.
Topics: Adenosine Diphosphate; Blood Platelets; Cell Membrane; Ferritins; Fibrinogen; Frozen Sections; Gold; Humans; Microscopy, Electron; Organoids; Platelet Aggregation; Staphylococcal Protein A; Thrombin | 1985 |
Induction of platelet aggregation by immune complexes.
Topics: Adenosine Diphosphate; Antigen-Antibody Complex; Blood Coagulation Factors; Blood Platelets; Calcium; Carbon Isotopes; Complement System Proteins; Fibrinogen; gamma-Globulins; Humans; Kinins; Latex; Microspheres; Phagocytosis; Platelet Adhesiveness; Serotonin; Surface Properties | 1970 |
Effect of heparin on platelets.
Topics: Adenosine Diphosphate; Afibrinogenemia; Blood Platelets; Cell Aggregation; Drug Synergism; Epinephrine; Fibrinogen; Heparin; Humans; Platelet Adhesiveness | 1972 |
Aggregation of human gel-filtered platelets. Requirement of apyrase and proteins.
Topics: Adenosine Diphosphate; Albumins; Blood Platelets; Calcium; Cell Aggregation; Chromatography, Gel; Fibrinogen; gamma-Globulins; Humans; Methods; Phosphoric Monoester Hydrolases; Polysaccharides | 1972 |
Enhanced platelet function in glomerular renal disease.
Topics: Adenosine Diphosphate; Adolescent; Aspirin; Beta-Globulins; Blood Cell Count; Blood Platelets; Child; Child, Preschool; Chromatography, Gel; Collagen; Female; Fibrinogen; Glomerulonephritis; Hematocrit; Humans; Immunoglobulin G; Male; Nephrotic Syndrome; Proteinuria; Serum Albumin | 1973 |
Adenosine diphosphate-induced platelet aggregation in healthy women with and without a combined and sequential contraceptive pill.
Topics: Adenosine Diphosphate; Adult; Blood Coagulation Tests; Blood Sedimentation; Chlormadinone Acetate; Contraceptives, Oral; Ethinyl Estradiol; Female; Fibrinogen; Humans; Male; Menstruation; Mestranol; Middle Aged; Ovulation; Platelet Adhesiveness; Statistics as Topic; Uric Acid | 1973 |
Nucleotide leakage from platelets in artificial media: prevention by albumin and other macromolecules and relation to ADP-induced platelet aggregation.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Beta-Globulins; Blood Platelets; Centrifugation, Density Gradient; Chromatography, Gel; Depression, Chemical; Dextrans; Fibrinogen; gamma-Globulins; Platelet Adhesiveness; Rabbits; Serum Albumin; Stimulation, Chemical | 1973 |
Willebrand factor and ristocetin. I. Mechanism of rustocetin-induced platelet aggregation.
Topics: Adenosine Diphosphate; Albumins; Aspirin; Carbon Radioisotopes; Chromatography, Gel; Dose-Response Relationship, Drug; Factor VIII; Fibrinogen; gamma-Globulins; Hemophilia A; Humans; Platelet Adhesiveness; Platelet Aggregation; Ristocetin; Serotonin; von Willebrand Diseases | 1974 |
Current concepts of hemostasis. Progress report on platelet aggregation.
Topics: Adenosine Diphosphate; Blood Platelets; Catecholamines; Dextrans; Fibrinogen; Hemostasis; Histamine H1 Antagonists; Humans; Phenylbutazone; Platelet Adhesiveness; Serotonin; Sulfinpyrazone | 1968 |
The effect of carbenicillin on the haemostatic mechanism.
Topics: Adenosine Diphosphate; Blood Coagulation; Blood Coagulation Tests; Carbenicillin; Factor XIII; Fibrinogen; Humans; In Vitro Techniques; Plasminogen; Platelet Adhesiveness; Prothrombin Time; Thrombin; Thromboplastin | 1973 |
Thrombocytopathia with abnormalities in platelet release reaction. Some evidence for platelet factor 4 deficiency.
Topics: Acid Phosphatase; Adenosine Diphosphate; Aged; Aspirin; Blood Coagulation Factors; Blood Coagulation Tests; Blood Platelet Disorders; Collagen; Epinephrine; Fibrinogen; Glucuronidase; Heparin; Humans; Male; Platelet Adhesiveness; Thrombin | 1973 |
Platelet defect in a case of Ehlers-Danlos syndrome.
Topics: Adenosine Diphosphate; Blood Cell Count; Blood Coagulation Tests; Blood Platelet Disorders; Blood Platelets; Collagen; Ehlers-Danlos Syndrome; Epinephrine; Fibrinogen; Humans; Male; Middle Aged; Neural Conduction; Platelet Adhesiveness; Prothrombin Time; Spectrophotometry | 1973 |
On the mechanism by which bovine fibrinogen induces the release and availability reaction of human blood platelets.
Topics: Acid Phosphatase; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Blood Coagulation; Blood Platelets; Calcium; Cattle; Cell Membrane; Edetic Acid; Fibrinogen; Humans; Platelet Adhesiveness; Thromboplastin; Time Factors | 1973 |
Bovine fibrinogen-induced platelet factor 3 and acid phosphatase availability in human platelets.
Topics: Acid Phosphatase; Adenosine; Adenosine Diphosphate; Animals; Blood Platelets; Cattle; Dose-Response Relationship, Drug; Edetic Acid; Fibrinogen; Humans; Platelet Adhesiveness; Stimulation, Chemical; Thromboplastin; Time Factors | 1973 |
The effect of anti-inflammatory drugs on the aggregation and adhesiveness of platelets, red cells and leukocytes.
Topics: Adenosine Diphosphate; Aminosalicylic Acids; Animals; Anti-Inflammatory Agents; Antigen-Antibody Complex; Cell Adhesion; Chloroquine; Collagen; Dextrans; Edetic Acid; Endotoxins; Erythrocytes; Fibrinogen; Flufenamic Acid; Gelatin; Humans; In Vitro Techniques; Indomethacin; Leukocytes; Phenylbutazone; Phenylpropionates; Platelet Adhesiveness; Prednisolone; Rats; Thrombosis | 1972 |
Thrombocytopenia in experimental trypanosomiasis.
Topics: Adenosine; Adenosine Diphosphate; Animals; Blood Cell Count; Blood Platelets; Chymotrypsin; Complement System Proteins; Disseminated Intravascular Coagulation; Edetic Acid; Fibrin; Fibrinogen; Hematocrit; Humans; In Vitro Techniques; Male; Microscopy, Electron; Platelet Adhesiveness; Rabbits; Rats; Thrombocytopenia; Trypanosomiasis; Trypsin; Trypsin Inhibitors | 1974 |
Platelet function and coagulation profile in lupus erythematosus. Studies in 50 patients.
Topics: Adenosine Diphosphate; Adult; Aged; Antibodies, Anti-Idiotypic; Anticoagulants; Blood Cell Count; Blood Coagulation; Blood Coagulation Tests; Blood Platelets; Chromatography, Gel; Connective Tissue; Epinephrine; Female; Fibrinogen; Hemagglutination Inhibition Tests; Humans; Immunoassay; Immunodiffusion; Immunoelectrophoresis; Immunoglobulin Fragments; Lupus Erythematosus, Systemic; Male; Middle Aged; Platelet Adhesiveness; Platelet Aggregation; Thromboplastin | 1974 |
The influence of prostaglandins E1 and E2 on platelet aggregation in mammals.
Topics: Adenosine Diphosphate; Animals; Collagen; Dogs; Epinephrine; Fibrinogen; Guinea Pigs; Humans; Platelet Adhesiveness; Platelet Aggregation; Prostaglandins; Rabbits; Sheep; Species Specificity; Swine | 1974 |
Inhibition of human platelet aggregation by plasmin digests of human factor VIII.
Topics: Adenosine Diphosphate; Antigens; Chromatography, Gel; Collagen; Epinephrine; Factor VIII; Fibrinogen; Fibrinolysin; Hemagglutination Inhibition Tests; Humans; Platelet Adhesiveness | 1973 |
Human platelet clumping by bovine fibrinogen.
Topics: Adenosine; Adenosine Diphosphate; Afibrinogenemia; Animals; Aspirin; Blood Platelets; Cattle; Chromatography, Gel; Depression, Chemical; Edetic Acid; Fibrinogen; Fibrinolysin; Hot Temperature; Humans; Male; Plasma; Platelet Adhesiveness | 1972 |
Megacaryocytoasthenia and megacaryocytopathy, new names, old diseases.
Topics: Acid Phosphatase; Adenosine Diphosphate; Adenosine Triphosphatases; Anemia, Sideroblastic; Animals; Blood Coagulation Disorders; Blood Platelets; Blood Proteins; Cell Nucleolus; Cell Nucleus; Cell Survival; Cytoplasm; Electrophoresis; Fibrinogen; Humans; Immune Sera; Leukemia; Megakaryocytes; Neuraminic Acids; Platelet Adhesiveness; Rabbits | 1972 |
Inhibition of human platelet aggregation by plasmin digests of human and bovine fibrinogen preparations: role of contaminating factor VIII-related material.
Topics: Adenosine Diphosphate; Animals; Antibodies; Anticoagulants; Antigens; Aprotinin; Cattle; Chromatography, DEAE-Cellulose; Chromatography, Gel; Dialysis; Electrophoresis; Factor VIII; Fibrinogen; Fibrinolysin; Humans; Platelet Adhesiveness; Rabbits; Thrombin | 1974 |
[Aggregating action of phospholipase C of Clostridium welchii on human platelets].
Topics: Adenosine Diphosphate; Blood Platelets; Cell Aggregation; Clostridium perfringens; Fibrinogen; Humans; Phosphatidylcholines; Phospholipases; Platelet Adhesiveness; Time Factors | 1971 |
Preparation of suspensions of washed platelets from humans.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Blood Platelets; Carbon Isotopes; Centrifugation; Fibrinogen; Heparin; Humans; Isotonic Solutions; Methods; Phosphoric Monoester Hydrolases; Platelet Adhesiveness; Time Factors | 1972 |
Influence of human ceruloplasmin on the aggregation of human platelets by adenosine diphosphate.
Topics: Adenosine Diphosphate; Ceruloplasmin; Chromatography, Gel; Ethylenes; Fibrinogen; Glycols; Humans; Neuraminidase; Oxidation-Reduction; Periodic Acid; Platelet Adhesiveness | 1974 |
The influence of benzamidine derivatives on human platelet function.
Topics: Adenosine; Adenosine Diphosphate; Amidines; Aminobenzoates; Anilides; Blood Coagulation; Blood Coagulation Tests; Clot Retraction; Collagen; Fibrinogen; Humans; Methyl Ethers; Nitro Compounds; Phosphoric Diester Hydrolases; Platelet Adhesiveness; Serotonin; Thrombin | 1974 |
Effect of ADP-induced shape change on incorporation of 32P into platelet phosphatidic acid and mono-, di- and triphosphatidyl inositol.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Calcium; Cyclic AMP; Ethers; Fibrinogen; Humans; Imides; In Vitro Techniques; Phosphates; Phosphatidylinositols; Phospholipids; Phosphorus Isotopes; Platelet Adhesiveness; Prostaglandins; Rabbits; Stimulation, Chemical; Swine | 1973 |
The effect of factor IX and factor X on blood platelets.
Topics: Adenosine Diphosphate; Blood Coagulation; Blood Platelets; Chromatography, Gel; Depression, Chemical; Factor IX; Factor X; Fibrinogen; Humans; Phosphatidylethanolamines; Phosphoric Monoester Hydrolases; Platelet Adhesiveness; Platelet Aggregation; Stimulation, Chemical; Thrombin | 1974 |
Comparative hemostasis: studies on elasmobranchs.
Topics: Adenosine Diphosphate; Animals; Blood Coagulation; Blood Coagulation Tests; Blood Platelets; Calcium Chloride; Factor XIII; Fibrinogen; Fishes; Hemostasis; Humans; Prothrombin; Sharks; Species Specificity; Thrombin | 1972 |
[Pathogenetic aspects of cellular hemostasis in ischemic heart disease].
Topics: Adenosine Diphosphate; Angina Pectoris; Arteriosclerosis; Basophils; Blood Coagulation; Blood Platelets; Coronary Disease; Fibrinogen; Humans; Myocardial Infarction; Platelet Adhesiveness; Platelet Aggregation | 1974 |
Induction of aggregation and of the release reaction in human platelets by polylysine.
Topics: Adenosine Diphosphate; Blood Platelets; Carbon Radioisotopes; Circular Dichroism; Densitometry; Dose-Response Relationship, Drug; Fibrinogen; Humans; Hydrogen-Ion Concentration; Lysine; Molecular Weight; Platelet Adhesiveness; Platelet Aggregation; Serotonin | 1974 |
Effect of shear stress on clot structure formation.
Topics: Adenosine Diphosphate; Blood Cell Count; Blood Coagulation; Blood Platelets; Blood Viscosity; Calcium; Clot Retraction; Collagen; Elasticity; Fibrin; Fibrinogen; Hemolysis; Humans; Platelet Adhesiveness | 1974 |
Alterations in platelet aggregation associated with adjuvant arthritis in rats.
Topics: Adenosine Diphosphate; Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Collagen; Disease Models, Animal; Female; Fibrinogen; Indomethacin; Mycobacterium; Phenylbutazone; Platelet Adhesiveness; Platelet Aggregation; Rats; Time Factors | 1974 |
Fibrinolysis and haemostasis.
Topics: Adenosine Diphosphate; Antithrombins; Biodegradation, Environmental; Blood Coagulation Tests; Blood Platelets; Cell Aggregation; Collagen; Fibrin; Fibrinogen; Fibrinolysis; Hemostasis; Humans; Platelet Adhesiveness; Streptokinase; Thrombin | 1972 |
Platelet-function studies in the Bernard-Soulier syndrome.
Topics: Adenosine Diphosphate; Blood Cell Count; Blood Coagulation Tests; Blood Platelet Disorders; Blood Platelets; Collagen; Consanguinity; Epinephrine; Epistaxis; Female; Fibrinogen; Humans; India; Male; Menorrhagia; Pedigree; Platelet Adhesiveness; Prothrombin Time; Purpura, Thrombocytopenic; Splenectomy; Syndrome; Thrombin; United States | 1972 |
Platelet interaction with fibrinogen and fibrin: comparison of the interaction of platelets with that of fibroblasts, leukocytes, and erythrocytes.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Clot Retraction; Erythrocytes; Fibrin; Fibrinogen; Fibroblasts; Humans; Iodine Isotopes; Leukocytes; Platelet Adhesiveness; Swine; Trypsin | 1972 |
In vitro potentiation of urokinase-activated lysis of human fibrin clots.
Topics: Adenosine Diphosphate; Blood Coagulation; Drug Synergism; Fibrin; Fibrinogen; Fibrinolysis; Fibrinolytic Agents; Flavin-Adenine Dinucleotide; Humans; In Vitro Techniques; Iodine Radioisotopes; Purine Nucleotides; Purines; Pyrimidine Nucleotides; Pyrimidines; Thrombin; Urokinase-Type Plasminogen Activator | 1974 |
Direct assessment of platelet adhesion to glass: a study of the forces of interaction and the effects of plasma and serum factors, platelet function, and modification of the glass surface.
Topics: Adenosine Diphosphate; Adsorption; Anticoagulants; Aspirin; Blood Coagulation; Blood Coagulation Factors; Blood Coagulation Tests; Blood Group Incompatibility; Calcium; Fibrinogen; Glass; Hemophilia A; Humans; Magnesium; Platelet Adhesiveness; Polyethylenes; Temperature; Thrombin; von Willebrand Diseases | 1972 |
In vitro platelet adhesiveness. Methods of study and clinical significance.
Topics: Adenosine Diphosphate; Anticoagulants; Blood Proteins; Citrates; Erythrocytes; Fibrinogen; Glass; Hemophilia A; Humans; Immune Sera; In Vitro Techniques; Platelet Adhesiveness; Thrombin; von Willebrand Diseases | 1972 |
Hereditary giant platelet syndrome: a disorder of a new aspect of platelet function.
Topics: Adenosine Diphosphate; Adolescent; Blood Platelet Disorders; Child; Collagen; Female; Fibrinogen; Hemorrhage; Humans; Plasma; Platelet Adhesiveness; Prothrombin; Purpura, Thrombocytopenic; Ristocetin; Syndrome; Thrombin; von Willebrand Diseases | 1973 |
Platelet responses to ristocetin in von Willebrand's disease.
Topics: Adenosine Diphosphate; Blood Platelets; Factor VIII; Female; Fibrinogen; Humans; Male; Platelet Adhesiveness; Ristocetin; Stimulation, Chemical; von Willebrand Diseases | 1974 |
Familial bleeding disorder with a moderate thrombocytopenia and giant blood platelets.
Topics: Adenosine Diphosphate; Aged; Blood Cell Count; Blood Coagulation Disorders; Blood Coagulation Tests; Blood Platelets; Blood Proteins; Collagen; Electrophoresis; Female; Fibrinogen; Gastrointestinal Hemorrhage; Humans; Male; Microscopy, Electron; Middle Aged; Platelet Aggregation; Ristocetin; Sialic Acids; Stimulation, Chemical; Thrombocytopenia | 1974 |
Hematologic assays in pre-eclampsia.
Topics: Adenosine Diphosphate; Adult; Blood Cell Count; Blood Coagulation Tests; Blood Platelets; Disseminated Intravascular Coagulation; Female; Fibrin; Fibrinogen; Humans; Labor, Obstetric; Microscopy, Phase-Contrast; Platelet Adhesiveness; Postpartum Period; Pre-Eclampsia; Pregnancy; Protamines; Prothrombin Time; Thrombocytopenia; Time Factors | 1974 |
Platelet interaction with polymerizing fibrin.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Animals; Blood Platelets; Cattle; Cell Aggregation; Chelating Agents; Edetic Acid; Fibrin; Fibrinogen; Hirudins; Humans; Iodine Isotopes; Isoflurophate; L-Lactate Dehydrogenase; Microscopy, Electron; Platelet Adhesiveness; Polymers; Prostaglandins; Rabbits; Serotonin; Swine; Thrombin; Tritium | 1972 |
Platelet shape change and aggregation.
Topics: Adenosine Diphosphate; Blood Platelet Disorders; Blood Platelets; Collagen; Edetic Acid; Fibrinogen; Humans; Optics and Photonics; Platelet Adhesiveness | 1972 |
A qualitative platelet defect in severe vitamin B 12 deficiency. Response, hyperresponse, and thrombosis after vitamin B 12 therapy.
Topics: Adenosine Diphosphate; Aged; Biological Assay; Blood Cell Count; Blood Coagulation Factors; Blood Coagulation Tests; Blood Platelet Disorders; Collagen; Colorimetry; Epinephrine; Female; Fibrinogen; Folic Acid; Humans; Lacticaseibacillus casei; Male; Middle Aged; Platelet Adhesiveness; Prothrombin Time; Radioisotope Dilution Technique; Schilling Test; Thromboplastin; Thrombosis; Vitamin B 12; Vitamin B 12 Deficiency | 1973 |
Studies on blood coagulation, fibrinolysis and platelet function following exercise in normal and splenectomized people.
Topics: Adenosine Diphosphate; Aminocaproates; Antigens; Blood Coagulation; Blood Coagulation Factors; Blood Platelets; Factor VIII; Fibrinogen; Fibrinolysis; Humans; Phospholipids; Physical Exertion; Plasminogen; Platelet Adhesiveness; Spleen; Splenectomy | 1972 |
Platelet factor-4--methods of study.
Topics: Adenosine Diphosphate; Blood Coagulation Factors; Blood Platelets; Female; Fibrinogen; Freezing; Heparin; Heparin Antagonists; Humans; Male; Methods; Platelet Adhesiveness; Surface-Active Agents; Thrombin; Thromboplastin | 1972 |
Density gradient separation of human platelets from plasma and the role of plasma in adenosine diphosphate induced platelet electrophoretic mobility changes.
Topics: Adenosine Diphosphate; Blood Platelets; Calcium; Centrifugation, Density Gradient; Electrophoresis; Fibrinogen; Humans; Myocardial Infarction; Phosphatidylcholines; Plasma; Platelet Adhesiveness | 1972 |
The possible role of platelets as trigger in intravascular coagulation associated with acute hyperparathyroidism.
Topics: Adenosine Diphosphate; Animals; Aspirin; Blood Cell Count; Blood Platelets; Calcium; Carcinoma 256, Walker; Collagen; Disseminated Intravascular Coagulation; Female; Fibrinogen; Hypercalcemia; Hyperparathyroidism; Neoplasm Transplantation; Parathyroid Hormone; Platelet Adhesiveness; Radiation Effects; Rats; Sarcoma, Yoshida; Thromboplastin; Time Factors; Transplantation, Homologous | 1972 |
Platelet function tests in pre- and post-operative patients with and without thrombosis.
Topics: Adenosine Diphosphate; Blood Cell Count; Blood Coagulation Factors; Blood Coagulation Tests; Blood Platelets; Collagen; Epinephrine; Fibrinogen; Humans; Injections, Intravenous; Iodine Radioisotopes; Lipoproteins; Phospholipids; Platelet Adhesiveness; Postoperative Complications; Radionuclide Imaging; Surgical Procedures, Operative; Thrombin; Thrombophlebitis | 1972 |
Aggregation and release reaction in normal and abnormal platelets.
Topics: Adenosine Diphosphate; Aspirin; Blood Coagulation Factors; Blood Platelet Disorders; Blood Platelets; Calcium; Centrifugation; Collagen; Depression, Chemical; Dose-Response Relationship, Drug; Epinephrine; Fibrinogen; Humans; In Vitro Techniques; Kaolin; Magnesium; Platelet Adhesiveness; Stimulation, Chemical; Temperature; Thrombin | 1972 |
A quantitative evaluation of the inhibition of platelet aggregation by low molecular weight degradation products of fibrinogen.
Topics: Adenosine Diphosphate; Chromatography, Thin Layer; Collagen; Drug Interactions; Electrophoresis; Epinephrine; Fibrinogen; Humans; In Vitro Techniques; Molecular Weight; Peptides; Platelet Adhesiveness; Streptokinase; Thrombin; Trypsin; Ultrafiltration | 1973 |
On the fine structure and aggregation requirements of gel filtered platelets (GFP).
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Calcium; Cattle; Cell Separation; Centrifugation; Chromatography, Gel; Cricetinae; Cytoplasm; Fibrinogen; Magnesium; Microscopy, Electron; Organoids; Platelet Adhesiveness; Serum Albumin, Bovine; Stimulation, Chemical | 1973 |
[Aggregation of human platelets after induction by bovine fibrinogen (author's transl)].
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Cattle; Fibrinogen; Humans; Platelet Adhesiveness | 1973 |
Effects of green pit viper (Trimeresurus erythrurus and Trimeresurus popeorum) venoms on blood coagulation, platelets and the fibrinolytic enzyme systems: studies in vivo and in vitro.
Topics: Adenosine Diphosphate; Adolescent; Blood Cell Count; Blood Coagulation; Blood Coagulation Tests; Blood Platelets; Child; Child, Preschool; Factor IX; Factor V; Factor VII; Factor VIII; Factor X; Female; Fibrinogen; Fibrinolysis; Humans; In Vitro Techniques; Infant; Male; Platelet Adhesiveness; Prothrombin Time; Snake Bites; Venoms | 1973 |
Human fibrinopeptides as antithrombins.
Topics: Adenosine Diphosphate; Antithrombins; Blood Coagulation; Blood Platelets; Carbon Radioisotopes; Collagen; Esterases; Fibrin; Fibrinogen; Humans; Peptides; Platelet Adhesiveness; Serotonin; Thrombin | 1973 |
Clotting mechanisms in patients with hypertriglyceridemia during therapy with anabolic or progestational drugs.
Topics: Adenosine Diphosphate; Blood Coagulation; Cholesterol; Electrophoresis, Paper; Factor IX; Factor V; Factor VII; Factor VIII; Factor X; Female; Fibrinogen; Follow-Up Studies; Humans; Hyperlipidemias; Male; Norethindrone; Oxandrolone; Prothrombin; Prothrombin Time; Thrombin; Triglycerides | 1973 |
The effect of thrombin, reptilase, and a fibrinopeptide B-releasing enzyme from the venom of the southern copperhead snake on rabbit platelets.
Topics: Adenosine Diphosphate; Animals; Blood Coagulation; Blood Platelets; Chromatography, Gel; Fibrinogen; Peptide Hydrolases; Peptides; Platelet Adhesiveness; Rabbits; Snakes; Thrombin; Venoms | 1973 |
Exploration of intraglomerular phenomena by measurement of the level of fibrin degradation products in the renal vein blood.
Topics: Adenosine Diphosphate; Adult; Animals; Blood Cell Count; Blood Coagulation; Blood Coagulation Tests; Blood Platelets; Erythrocytes; Female; Fibrin; Fibrinogen; Glomerulonephritis; Hemagglutination Inhibition Tests; Humans; Immunoglobulin A; Immunoglobulin G; Kidney Glomerulus; Male; Middle Aged; Nephritis; Platelet Aggregation; Polymers; Renal Veins; Sheep; Thrombin | 1973 |
Intraoperative autotransfusion.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Blood Transfusion, Autologous; Cattle; Chromium Isotopes; Epinephrine; Erythrocyte Count; Erythrocytes; Fibrin; Fibrinogen; Hematocrit; Heparin; Humans; Platelet Aggregation; Serotonin; Surgical Procedures, Operative | 1973 |
Platelet aggregation after thermal injury.
Topics: Adenosine Diphosphate; Animals; Blood Cell Count; Blood Platelets; Blood Urea Nitrogen; Burns; Calcium; Factor VIII; Fibrinogen; Male; Platelet Adhesiveness; Prothrombin Time; Rats; Thrombin; Time Factors | 1974 |
Platelet aggregation and clot retraction by two preparations of staphylocoagulase.
Topics: Adenosine Diphosphate; Afibrinogenemia; Clot Retraction; Coagulase; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Epinephrine; Fibrinogen; Humans; Platelet Adhesiveness; Sodium Dodecyl Sulfate; Thrombin | 1974 |
Enzymatic basis for platelet aggregation and release: the significance of the 'platelet atmosphere' and the relationship between platelet function and blood coagulation.
Topics: Acetates; Adenosine Diphosphate; Arginine; Blood Coagulation; Blood Coagulation Factors; Blood Platelets; Chlorine; Factor XIII; Fibrin; Fibrinogen; Hemostasis; Humans; Hydrolysis; In Vitro Techniques; Male; Plasma; Platelet Adhesiveness; Prothrombin; Thrombin; Tosyl Compounds; Urea | 1974 |
Haemostatic defects in polycythaemia vera.
Topics: Adenosine Diphosphate; Adult; Aged; Antithrombins; Blood Cell Count; Blood Coagulation; Blood Coagulation Factors; Blood Coagulation Tests; Blood Platelets; Clot Retraction; Collagen; Disseminated Intravascular Coagulation; Epinephrine; Female; Fibrin; Fibrinogen; Fibrinolysis; Hemorrhage; Humans; Male; Middle Aged; Plasminogen; Platelet Adhesiveness; Polycythemia Vera; Prothrombin Time; Thrombin; Thrombophlebitis | 1974 |
Platelet aggregation and release by ADP and thrombin: evidence for two separate effects of ADP on platelets, involvement of fibrinogen in release, and mechanism of inhibitory action of acetylsalicylic acid.
Topics: Adenosine Diphosphate; Aspirin; Blood Coagulation Factors; Blood Platelets; Fibrin; Fibrinogen; Heparin; Humans; In Vitro Techniques; Models, Biological; Models, Theoretical; Platelet Adhesiveness; Prothrombin; Pyrophosphatases; Spectrophotometry; Surface Properties; Thrombin | 1974 |
Studies on experimental defibrination. I. Microcirculatory observations.
Topics: Adenosine Diphosphate; Animals; Blood Coagulation; Cheek; Cricetinae; Ear, External; Embolism; Female; Fibrin; Fibrinogen; Injections, Intraperitoneal; Injections, Intravenous; Leukocytes; Male; Microcirculation; Microscopy, Phase-Contrast; Platelet Adhesiveness; Rabbits; Sulfonic Acids; Thromboplastin | 1969 |
Platelet electrophoresis: effect of defibrination by ancrod (Arvin).
Topics: Acute Disease; Adenosine Diphosphate; Anticoagulants; Blood Platelets; Electrophoresis; Fibrinogen; Humans; Norepinephrine; Plasminogen; Vascular Diseases; Venoms | 1972 |
Effects of arvin on blood platelets. In vitro and in vivo studies.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Anticoagulants; Blood Coagulation; Blood Platelets; Calcium Chloride; Clot Retraction; Fibrinogen; Hemolysin Proteins; Humans; In Vitro Techniques; Methionine; Platelet Adhesiveness; Potassium; Rabbits; Selenium; Serotonin; Snakes; Thrombin; Venoms | 1972 |
Localization of ferritin-conjugated anti-fibrin-fibrinogen in platelet aggregates produced in vitro.
Topics: Adenosine Diphosphate; Antigen-Antibody Complex; Blood Platelets; Ferritins; Fibrinogen; Humans; Immunoelectrophoresis; In Vitro Techniques; Microscopy, Electron; Platelet Adhesiveness; Thrombosis | 1972 |
Fibrin monomer and platelet aggregation in vitro and in vivo.
Topics: Adenosine Diphosphate; Aminocaproates; Animals; Blood Cell Count; Cattle; Collagen; Ethanol; Fibrin; Fibrinogen; Heparin; Humans; In Vitro Techniques; Platelet Adhesiveness; Rabbits; Spectrum Analysis | 1972 |
Requirements for aggregation of washed human platelets suspended in buffered salt solutions.
Topics: Adenosine Diphosphate; Buffers; Calcium; Cell Membrane; Epinephrine; Fibrinogen; Humans; Platelet Adhesiveness; Serotonin; Thrombin | 1972 |
Coagulation, fibrinolysis and platelet function in pre-eclampsia, essential hypertension and placental insufficiency.
Topics: Adenosine Diphosphate; Adult; Antithrombins; Blood Cell Count; Blood Coagulation; Blood Coagulation Tests; Blood Platelets; Cold Temperature; Factor V; Factor VIII; Female; Fibrin; Fibrinogen; Fibrinolysis; Fibrinolytic Agents; Humans; Hypertension; Placenta; Placenta Diseases; Plasminogen; Platelet Adhesiveness; Postpartum Period; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Thromboplastin | 1971 |
Platelet aggregation in washed suspensions.
Topics: Adenosine Diphosphate; Blood Platelets; Calcium; Cell Aggregation; Cold Temperature; Collagen; Drug Synergism; Epinephrine; Fibrinogen; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Magnesium | 1971 |
Gray platelet syndrome. A variety of qualitative platelet disorder.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Blood Platelet Disorders; Blood Platelets; Blood Proteins; Child; Chromatography, Gas; Chromatography, Thin Layer; Collagen; Epinephrine; Fatty Acids; Fibrinogen; Hemostasis; Humans; Male; Microscopy, Electron; Phosphatidylethanolamines; Phospholipids; Platelet Adhesiveness; Prednisone; Skin Manifestations; Spleen; Splenectomy | 1971 |
Effect of vasopressin on human blood platelets.
Topics: Adenosine Diphosphate; Blood Platelets; Calcium; Carbon Isotopes; Creatine Kinase; Densitometry; Fibrinogen; Humans; Magnesium; Phosphocreatine; Platelet Adhesiveness; Receptors, Drug; Serotonin; Vasopressins | 1971 |
Action of fibrinogen degradation products and fibrin monomer soluble complexes on platelet aggregation.
Topics: Acid Phosphatase; Adenosine Diphosphate; Antigens; Aspirin; Blood Coagulation; Chromatography, Gel; Collagen; Dialysis; Epinephrine; Fibrin; Fibrinogen; Hot Temperature; Humans; Hydrogen-Ion Concentration; Molecular Weight; Phosphoenolpyruvate; Platelet Adhesiveness; Pyruvate Kinase; Solubility; Thrombin | 1971 |
Pharmacological modification of urinary excretion of fibrinogen-like material in glomerulonephritis.
Topics: Adenosine Diphosphate; Collagen; Epinephrine; Fibrinogen; Glomerulonephritis; Hemagglutination Inhibition Tests; Humans; Immunoassay; Indomethacin; Platelet Adhesiveness; Proteinuria | 1971 |
Platelet disaggregation and the degradation of ADP in the plasma.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Altitude; Animals; Blood Coagulation; Blood Platelets; Carbon Isotopes; Collagen; Dogs; Fibrinogen; Guinea Pigs; Hematocrit; Horses; Humans; Leukemia, Myeloid; Rabbits; Rats; Time Factors | 1971 |
Protein requirement for platelet aggregation.
Topics: Adenosine Diphosphate; Afibrinogenemia; Animals; Blood Coagulation Tests; Blood Platelet Disorders; Blood Platelets; Blood Proteins; Blood Transfusion; Cattle; Epinephrine; Fibrinogen; Humans; Immunoglobulin G; Male; Phospholipids; Platelet Adhesiveness; Thrombin; Time Factors | 1971 |
Constitutional and acquired abnormalities of platelet aggregation.
Topics: Acid Phosphatase; Adenosine; Adenosine Diphosphate; Aminohydrolases; Anemia, Sideroblastic; Blood Platelet Disorders; Blood Platelets; Bolivia; Carbon Isotopes; Collagen; Environment; Epinephrine; Fibrinogen; Hemagglutination; Heparin Antagonists; Humans; Immune Sera; Megakaryocytes; Microscopy, Electron; Neuraminic Acids; Nucleotides; Peru; Platelet Adhesiveness; Purpura, Thrombocytopenic; Racial Groups; Thrombocytopenia; Uremia | 1970 |
ADP-dependent common receptor mechanism for binding of von Willebrand factor and fibrinogen to human platelets.
Topics: Adenosine Diphosphate; Affinity Labels; Binding, Competitive; Blood Coagulation Factors; Blood Platelets; Fibrinogen; Platelet Membrane Glycoproteins; Receptors, Cell Surface; von Willebrand Factor | 1984 |
Platelet aggregation: its relation with ADP-induced fibrinogen binding to platelets and ADP-related membrane enzyme activities.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Blood Platelets; Cell Membrane; Creatine Kinase; Fibrinogen; Humans; Phosphocreatine; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptors, Cell Surface | 1984 |
In vivo effect of ticlopidine on fibrinogen-platelet cofactor activity and binding of fibrinogen to platelets.
Topics: Adenosine Diphosphate; Anticoagulants; Blood Platelets; Fibrinogen; Humans; In Vitro Techniques; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Thiophenes; Ticlopidine | 1984 |
[Thrombosis and diabetic angiopathy].
Topics: Adenosine Diphosphate; beta-Thromboglobulin; Blood Coagulation Factors; Blood Platelets; Diabetic Angiopathies; Fibrinogen; Fibrinolysis; Humans; Platelet Aggregation; Thrombosis | 1982 |
Exposure of platelet fibrinogen-binding sites by collagen, arachidonic acid, and ADP: inhibition by a monoclonal antibody to the glycoprotein IIb-IIIa complex.
Topics: Adenosine Diphosphate; Antibodies, Monoclonal; Arachidonic Acid; Arachidonic Acids; Binding Sites; Blood Platelets; Collagen; Fibrinogen; Glycoproteins; L-Lactate Dehydrogenase; Platelet Aggregation; Platelet Membrane Glycoproteins; Thromboxane B2 | 1983 |
Identification of two structurally and functionally distinct sites on human platelet membrane glycoprotein IIb-IIIa using monoclonal antibodies.
Topics: Adenosine Diphosphate; Antibodies, Monoclonal; Blood Platelets; Fibrinogen; Glycoproteins; Humans; Immunoelectrophoresis, Two-Dimensional; Membrane Proteins; Platelet Aggregation; Platelet Membrane Glycoproteins | 1983 |
Monoclonal antibodies against human platelet glycoprotein IIIa.
Topics: Adenosine Diphosphate; Animals; Antibodies, Monoclonal; Antibody Specificity; Blood Platelets; Collagen; Electrophoresis, Polyacrylamide Gel; Female; Fibrinogen; Glycoproteins; Humans; Membrane Proteins; Mice; Mice, Inbred BALB C; Platelet Aggregation; Platelet Membrane Glycoproteins | 1983 |
Effects of a selective thromboxane A2 synthetase inhibitor on immune complex glomerulonephritis.
Topics: Adenosine Diphosphate; Animals; Collagen; Fibrin Fibrinogen Degradation Products; Fibrinogen; Fibrinolysis; Glomerulonephritis; Imidazoles; Immune Complex Diseases; Kidney Glomerulus; Male; Oxidoreductases; Platelet Aggregation; Proteinuria; Rabbits; Thromboxane-A Synthase | 1984 |
Interaction of von Willebrand factor with human platelets in the plasma milieu.
Topics: Adenosine Diphosphate; Afibrinogenemia; Antibodies, Monoclonal; Blood Coagulation Factors; Blood Platelets; Blood Proteins; Epinephrine; Fibrinogen; Glycoproteins; Humans; Platelet Membrane Glycoproteins; Ristocetin; Thrombin; von Willebrand Diseases; von Willebrand Factor | 1984 |
Ultrastructural studies on the binding sites of fibrinogen on platelet surface during aggregation.
Topics: Adenosine Diphosphate; Binding Sites; Blood Platelets; Cell Membrane; Fibrinogen; Fibrinolysin; Humans; Microscopy, Electron; Platelet Aggregation; Thrombin | 1984 |
Platelet aggregation caused by dithiothreitol.
Topics: Adenosine Diphosphate; Adult; Alprostadil; Dithiothreitol; Electrophoresis, Polyacrylamide Gel; Female; Fibrinogen; Glycoproteins; Humans; Mercaptoethanol; Platelet Aggregation; Platelet Membrane Glycoproteins; Prostaglandins E | 1984 |
Fibrinogen competes with von Willebrand factor for binding to the glycoprotein IIb/IIIa complex when platelets are stimulated with thrombin.
Topics: Adenosine Diphosphate; Binding, Competitive; Blood Coagulation Factors; Blood Platelets; Fibrinogen; Glycoproteins; Humans; Membrane Proteins; Platelet Membrane Glycoproteins; Thrombin; von Willebrand Factor | 1984 |
Induction of the fibrinogen receptor on human platelets by epinephrine and the combination of epinephrine and ADP.
Topics: Adenosine Diphosphate; Binding, Competitive; Blood Platelets; Calcium; Epinephrine; Fibrinogen; Humans; Kinetics; Magnesium; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptors, Cell Surface | 1980 |
Exposure of fibrinogen receptor on human platelets by proteolytic enzymes.
Topics: Adenosine Diphosphate; Agglutination; Blood Platelets; Calcium; Chymotrypsin; Fibrinogen; Humans; Kinetics; Magnesium; Platelet Aggregation; Platelet Membrane Glycoproteins; Pronase; Receptors, Cell Surface; Thrombin | 1981 |
Interaction of fibrinogen with its platelet receptor: kinetics and effect of pH and temperature.
Topics: Adenosine Diphosphate; Blood Platelets; Fibrinogen; Humans; Hydrogen-Ion Concentration; Kinetics; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Temperature | 1981 |
Effects of chymotrypsin and adenosine diphosphate on the exposure of fibrinogen receptors on normal human and Glanzmann's thrombasthenic platelets.
Topics: Adenosine Diphosphate; Blood Platelet Disorders; Blood Platelets; Cell Membrane; Chymotrypsin; Fibrinogen; Humans; Kinetics; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptors, Cell Surface | 1981 |
Identification of two distinct adenosine diphosphate receptors in human platelets.
Topics: Adenosine; Adenosine Diphosphate; Blood Platelets; Chymotrypsin; Cyclic AMP; Fibrinogen; Humans; In Vitro Techniques; Platelet Aggregation; Receptors, Cell Surface; Receptors, Purinergic; Thionucleotides | 1980 |
Affinity labeling of a human platelet membrane protein with 5'-p-fluorosulfonylbenzoyl adenosine. Concomitant inhibition of ADP-induced platelet aggregation and fibrinogen receptor exposure.
Topics: Adenosine; Adenosine Diphosphate; Affinity Labels; Blood Platelets; Fibrinogen; Humans; Kinetics; Membrane Proteins; Platelet Aggregation; Platelet Membrane Glycoproteins; Protein Binding; Receptors, Cell Surface | 1981 |
A role for prostaglandins and thromboxanes in the exposure of platelet fibrinogen receptors.
Topics: Adenosine Diphosphate; Aspirin; Blood Platelets; Epinephrine; Fibrinogen; Humans; Indomethacin; Platelet Aggregation; Platelet Membrane Glycoproteins; Prostaglandins; Prostaglandins A; Prostaglandins H; Receptors, Cell Surface; Thromboxanes | 1981 |
The interaction of fibrinogen with human platelets in a plasma milieu.
Topics: Adenosine Diphosphate; Blood Platelets; Fibrinogen; Humans; In Vitro Techniques; Kinetics; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Temperature | 1982 |
Binding of fibrinogen molecules to pig platelets and their membranes.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Cell Membrane; Fibrinogen; Kinetics; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Swine | 1982 |
Arachidonate-induced fibrinogen binding to thrombin-degranulated rabbit platelets is independent of released ADP.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cytoplasmic Granules; Fibrin; Fibrinogen; Oligopeptides; Platelet Aggregation; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Thrombin | 1982 |
The binding of fibrinogen to its platelet receptor.
Topics: Adenosine Diphosphate; Blood Platelets; Fibrin Fibrinogen Degradation Products; Fibrinogen; Humans; Immunoglobulin Fab Fragments; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Temperature; Time Factors | 1982 |
Localization of a site interacting with human platelet receptor on carboxy-terminal segment of human fibrinogen gamma chain.
Topics: Adenosine Diphosphate; Amino Acids; Binding Sites; Blood Platelets; Cyanogen Bromide; Fibrinogen; Humans; Kinetics; Macromolecular Substances; Peptide Fragments; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptors, Cell Surface | 1982 |
The inhibitory effects of exogenous arachidonic acid on rabbit platelet aggregation and the release reaction.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Cyclic AMP; Cytoplasmic Granules; Fibrinogen; Platelet Aggregation; Rabbits; Serotonin; Thrombin | 1982 |
Platelet aggregation and exposure of fibrinogen receptors by prostaglandin endoperoxide analogues.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Dose-Response Relationship, Drug; Fibrinogen; Iodine Radioisotopes; Platelet Aggregation; Platelet Membrane Glycoproteins; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandins H; Receptors, Cell Surface | 1983 |
Inhibition of fibrinogen binding to stimulated human platelets by a monoclonal antibody.
Topics: Adenosine Diphosphate; Animals; Antibodies, Monoclonal; Blood Platelets; Chromatography, Affinity; Fibrinogen; Glycoproteins; Humans; Mice; Mice, Inbred C57BL; Molecular Weight; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptors, Cell Surface | 1983 |
Fibrinogen interaction with platelet receptors.
Topics: Adenosine Diphosphate; Blood Platelets; Cell Membrane; Chymotrypsin; Fibrinogen; Glycoproteins; Humans; Platelet Aggregation; Platelet Membrane Glycoproteins; Purpura, Thrombocytopenic; Receptors, Cell Surface; Structure-Activity Relationship; Syndrome | 1983 |
The fibrinogen-dependent pathway of platelet aggregation.
Topics: Adenosine Diphosphate; Blood Platelets; Calcimycin; Collagen; Epinephrine; Fibrinogen; Humans; Models, Biological; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptors, Cell Surface | 1983 |
Microenvironment changes of human blood platelet membranes associated with fibrinogen binding.
Topics: Adenosine Diphosphate; Blood Platelets; Calcium; Cell Membrane; Electron Spin Resonance Spectroscopy; Fibrinogen; Fluorescence Polarization; Humans; Membrane Fluidity; Spin Labels | 1983 |
[Introduction to the topic of thromboembolism].
Topics: Adenosine Diphosphate; Blood Coagulation Factors; Blood Platelets; Endothelium; Epoprostenol; Erythrocytes; Fibrinogen; Humans; Thromboembolism; Thromboxanes | 1984 |
Platelet aggregation in experimental diabetes and experimental galactosemia.
Topics: Adenosine Diphosphate; Animals; Collagen; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Dogs; Fibrinogen; Galactosemias; Glycated Hemoglobin; Insulin; Platelet Aggregation | 1984 |
von Willebrand factor binds to platelets and induces aggregation in platelet-type but not type IIB von Willebrand disease.
Topics: Adenosine Diphosphate; Apyrase; Blood Coagulation Factors; Blood Platelets; Factor VIII; Female; Fibrinogen; Humans; Male; Platelet Aggregation; Thrombin; von Willebrand Diseases; von Willebrand Factor | 1983 |
Adhesion and aggregation of thrombin prestimulated human platelets on surface-bound fibrinogen: evidence for involvement of ADP and arachidonic acid pathways.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Coagulation; Fibrinogen; Glass; Humans; In Vitro Techniques; Platelet Adhesiveness; Platelet Aggregation; Serotonin; Surface Properties; Thrombin | 1983 |
Effects of variant gamma chains and sialic acid content of fibrinogen upon its interactions with ADP-stimulated human and rabbit platelets.
Topics: Adenosine Diphosphate; Animals; Electrophoresis, Polyacrylamide Gel; Fibrinogen; Genetic Variation; Humans; Immunoglobulin gamma-Chains; Immunoglobulin Heavy Chains; Peptide Chain Termination, Translational; Platelet Aggregation; Rabbits; Sialic Acids; Sodium Dodecyl Sulfate | 1984 |
Effect of amino sugars on platelet aggregation and on fibrinogen binding.
Topics: Adenosine Diphosphate; Amino Sugars; Animals; Blood Platelets; Fibrinogen; Galactosamine; Glucosamine; Hexosamines; Humans; In Vitro Techniques; Platelet Adhesiveness; Platelet Aggregation; Rabbits; Serotonin | 1984 |
Role of thrombospondin in platelet aggregation.
Topics: Adenosine Diphosphate; Antigen-Antibody Reactions; Blood Platelets; Collagen; Fibrinogen; Glycoproteins; Humans; Immunoglobulin Fab Fragments; Kinetics; Platelet Aggregation; Thrombin; Thrombospondins | 1984 |
Thrombospondin plays a role in platelet-platelet recognition during release-related aggregation.
Topics: Adenosine Diphosphate; Antibodies, Monoclonal; Aspirin; Fibrinogen; Glycoproteins; Humans; Immune Sera; Platelet Aggregation; Thrombospondins | 1984 |
[Biophysical mechanisms and kinetics of thrombocyte aggregation].
Topics: Adenosine Diphosphate; Animals; Biophysical Phenomena; Biophysics; Blood Platelets; Calcium; Cell Communication; Dose-Response Relationship, Drug; Fibrinogen; Humans; Kinetics; Mathematics; Models, Biological; Platelet Aggregation; Platelet Count; Time Factors | 1984 |
The ability of fibrinogens, FI and FII, to support ADP-induced platelet aggregation.
Topics: Adenosine Diphosphate; Fibrin Fibrinogen Degradation Products; Fibrinogen; Humans; Molecular Weight; Platelet Aggregation | 1983 |
Measurements of platelet collision efficiency upon virgin and platelet-primed (foot-printed) fibrinogen with fluorescent video-microscopy.
Topics: Adenosine Diphosphate; Blood Platelets; Collagen; Fibrinogen; Glass; Humans; Microscopy, Fluorescence; Platelet Adhesiveness; Platelet Aggregation; Surface Properties; Thrombin | 1983 |
Observations on the effects of cytochalasin B and cytochalasin D on ADP- and chymotrypsin-treated platelets.
Topics: Adenosine Diphosphate; Agglutination; Blood Platelets; Chymotrypsin; Clot Retraction; Cytochalasin B; Cytochalasin D; Cytochalasins; Fibrinogen; Humans; Platelet Aggregation; Serotonin; Time Factors | 1984 |
Effects of oral contraceptives, or lanosterol, on ADP-induced aggregation and binding of 125I-fibrinogen to rat platelets.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Contraceptives, Oral; Female; Fibrinogen; In Vitro Techniques; Iodine Radioisotopes; Lanosterol; Platelet Aggregation; Rats | 1984 |
Effects of dietary linoleic acid on rat platelet ADP-induced aggregation and binding of 125I-fibrinogen.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Diet; Dose-Response Relationship, Drug; Fibrinogen; Iodine Radioisotopes; Linoleic Acids; Male; Platelet Aggregation; Rats; Rats, Inbred Strains | 1984 |
Platelet-platelet recognition during aggregation: distinct mechanisms determined by the release reaction.
Topics: Adenosine Diphosphate; Aspirin; Blood Platelets; Dose-Response Relationship, Drug; Fibrinogen; Humans; Platelet Aggregation | 1984 |
Interaction of normal, thrombasthenic, and Bernard-Soulier platelets with immobilized fibrinogen: defective platelet-fibrinogen interaction in thrombasthenia.
Topics: Acrylonitrile; Adenosine Diphosphate; Agglutination; Albumins; Apyrase; Blood Platelet Disorders; Blood Platelets; Cell Communication; Edetic Acid; Epinephrine; Fibrinogen; Humans; Immune Sera; Platelet Adhesiveness; Platelet Aggregation; Platelet Count; Thrombin | 1980 |
Correlation between fibrinogen binding to human platelets and platelet aggregability.
Topics: Adenosine Diphosphate; Apyrase; Binding Sites; Blood Platelet Disorders; Blood Platelets; Edetic Acid; Fibrinogen; Humans; Platelet Aggregation; Temperature | 1980 |
Changes in platelet functions, coagulation and fibrinolysis in uncomplicated cases of acute myocardial infarction.
Topics: Adenosine Diphosphate; Adult; Aged; alpha-2-Antiplasmin; Antithrombin III; Blood Coagulation; Blood Platelets; Collagen; Epinephrine; Factor VIII; Factor XIII; Female; Fibrin; Fibrinogen; Fibrinolysis; Humans; Male; Middle Aged; Myocardial Infarction; Partial Thromboplastin Time; Serotonin; Serum Globulins; Time Factors | 1980 |
Decreased association of 45calcium with platelets unable to aggregate due to thrombasthenia or prolonged calcium deprivation.
Topics: Adenosine Diphosphate; Blood Platelet Disorders; Blood Platelets; Calcium; Chromatography, Gel; Edetic Acid; Fibrinogen; Humans; In Vitro Techniques; Platelet Aggregation | 1980 |
Inhibitors of ADP-induced platelet aggregation prevent fibrinogen binding to rabbit platelets and cause rapid deaggregation and dissociation of bound fibrinogen.
Topics: Adenosine Diphosphate; Animals; Binding Sites; Blood Platelets; Caffeine; Colchicine; Cytochalasin B; Dipyridamole; Edetic Acid; Egtazic Acid; Epoprostenol; Fibrinogen; Humans; Platelet Aggregation; Prostaglandins E; Rabbits | 1981 |
Effect of ADP-induced platelet aggregation on lung fluid balance in sheep.
Topics: Adenosine Diphosphate; Animals; Blood Proteins; Carbon Dioxide; Fibrin; Fibrinogen; Leukocyte Count; Lung; Lymph; Oxygen; Platelet Aggregation; Platelet Count; Proteins; Sheep | 1982 |
Preliminary studies on indobufen (K 3920). A new inhibitor of platelet aggregation.
Topics: Adenosine Diphosphate; Arteriosclerosis; Blood Platelets; Fibrinogen; Humans; Indoles; Isoindoles; Phenylbutyrates; Platelet Aggregation; Platelet Factor 4 | 1981 |
The use of prostacyclin in the separation from plasma and washing of human platelets.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Cell Separation; Collagen; Dose-Response Relationship, Drug; Epinephrine; Epoprostenol; Female; Fibrinogen; Humans; Indomethacin; Male; Platelet Aggregation; Plateletpheresis; Prostaglandins; Time Factors | 1982 |
Binding of fibrinogen to ADP-treated platelets. Comparison of plasma fibrinogen fractions and early plasmic fibrinogen derivatives.
Topics: Adenosine Diphosphate; Blood Platelets; Fibrinogen; Humans; Peptide Fragments; Platelet Aggregation; Protein Conformation; Structure-Activity Relationship | 1983 |
[Hemostatis and protein glucosylation].
Topics: Adenosine Diphosphate; Blood Proteins; Diabetes Mellitus; Electrophoresis, Polyacrylamide Gel; Fibrinogen; Glucose; Glycated Hemoglobin; Humans; Platelet Aggregation; Protein Binding | 1983 |
Hemorheological effects of pentoxifylline on disturbed flow behavior of blood in patients with cerebrovascular insufficiency.
Topics: Adenosine Diphosphate; Blood Viscosity; Cerebrovascular Disorders; Epinephrine; Erythrocytes; Female; Fibrinogen; Humans; Male; Middle Aged; Pentoxifylline; Platelet Aggregation; Rheology; Theobromine | 1983 |
Are lysophosphatidic acids or phosphatidic acids involved in stimulus activation coupling in platelets?
Topics: Adenosine Diphosphate; Albumins; Blood Platelets; Calcium; Fibrinogen; Humans; Hydrogen-Ion Concentration; Lysophospholipids; Magnesium; Pharmaceutical Vehicles; Phosphatidic Acids; Platelet Aggregation; Thromboxanes | 1982 |
Inhibition of fibrinogen binding to human platelets by the tetrapeptide glycyl-L-prolyl-L-arginyl-L-proline.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Blood Platelets; Fibrinogen; Humans; Oligopeptides; Platelet Aggregation; Structure-Activity Relationship | 1982 |
Prostacyclin inhibits mobilisation of fibrinogen-binding sites on human ADP- and thrombin-treated platelets.
Topics: Adenosine Diphosphate; Binding Sites; Blood Platelets; Depression, Chemical; Epoprostenol; Fibrinogen; Humans; In Vitro Techniques; Platelet Aggregation; Prostaglandins; Protein Binding; Thrombin | 1980 |
An investigation into the role of coagulation factor XIII in ADP-induced aggregation and fibrinogen binding with rabbit platelets.
Topics: Adenosine Diphosphate; Animals; Antithrombin III; Apyrase; Creatine Kinase; Factor XIII; Fibrinogen; Heparin; Humans; Phosphocreatine; Platelet Aggregation; Protein Binding; Rabbits | 1982 |
Shape and functional properties of human platelets washed with acid citrate.
Topics: Adenosine Diphosphate; Blood Platelets; Blood Specimen Collection; Calcium; Citrates; Epinephrine; Fibrinogen; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Platelet Aggregation | 1981 |
Identical behavior of fibrinogen and asialo-fibrinogen in reactions with platelets during ADP-induced aggregation.
Topics: Adenosine Diphosphate; Animals; Binding Sites; Blood Coagulation; Blood Platelets; Cattle; Electrophoresis, Polyacrylamide Gel; Fibrinogen; Humans; Iodine Radioisotopes; Neuraminidase; Platelet Aggregation; Rabbits; Sialic Acids; Thrombin Time | 1980 |
ADP and epinephrine-induced release of platelet fibrinogen.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Calcium; Cattle; Chromatography, Gel; Epinephrine; Fibrinogen; Humans; Platelet Aggregation; Serum Albumin; Time Factors | 1981 |
The effect of phospholipase inhibitor mepacrine on platelet aggregation, the platelet release reaction and fibrinogen binding to the platelet surface.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acids; Blood Platelets; Carbon Radioisotopes; Collagen; Fibrinogen; Humans; Partial Thromboplastin Time; Phospholipases; Platelet Adhesiveness; Platelet Aggregation; Quinacrine; Rabbits; Time Factors | 1981 |
Interaction of fibrinogen with its platelet receptor as part of a multistep reaction in ADP-induced platelet aggregation.
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Calcium; Fibrinogen; Humans; Kinetics; Magnesium; Manganese; Platelet Aggregation; Receptors, Drug | 1980 |
Importance of the liver in the regulation of platelet activity: effect of its functional exclusion (Eck fistula).
Topics: Adenosine Diphosphate; Animals; Binding Sites; Blood Coagulation; Blood Platelets; Fibrinogen; Humans; Liver; Liver Cirrhosis; Platelet Aggregation; Platelet Count; Portacaval Shunt, Surgical; Rats | 1980 |
Cooperativity of albumin and aggrexons A and B for ADP-induced-aggregation of platelets.
Topics: Adenosine Diphosphate; Animals; Blood Proteins; Cattle; Chemical Precipitation; Fibrinogen; Platelet Aggregation; Serum Albumin, Bovine | 1980 |
Expression of thrombin-enhanced platelet lectin activity is controlled by secretion.
Topics: Adenosine Diphosphate; Agglutinins; Blood Platelets; Fibrinogen; Hemagglutinins; Humans; In Vitro Techniques; Membranes; Platelet Aggregation; Solubility; Thrombin | 1980 |
Reversibility of the association of fibrinogen with rabbit platelets exposed to ADP.
Topics: Adenosine Diphosphate; Animals; Apyrase; Binding Sites; Blood Platelets; Fibrinogen; Humans; Iodine Radioisotopes; Platelet Aggregation; Rabbits | 1980 |
Relationship of ADP-induced fibrinogen binding to platelet shape change and aggregation elucidated by use of colchicine and cytochalasin B.
Topics: Adenosine Diphosphate; Apyrase; Blood Platelets; Colchicine; Cytochalasin B; Fibrinogen; Humans; Platelet Aggregation | 1980 |
Participation of ADP in the binding of fibrinogen to thrombin-stimulated platelets.
Topics: Adenosine Diphosphate; Blood Platelets; Fibrinogen; Humans; Serotonin; Stimulation, Chemical; Thrombin; Time Factors | 1980 |
Effects of chymotrypsin on the release reaction and aggregation of blood platelets.
Topics: Adenosine Diphosphate; Blood Platelets; Chymotrypsin; Fibrinogen; Humans; Imipramine; Platelet Aggregation; Serotonin | 1980 |
Effect of fibrinogen on ADP-induced platelet aggregation.
Topics: Adenosine Diphosphate; Blood Platelets; Calcium; Cell Separation; Chromatography, Gel; Disulfides; Fibrinogen; Fibrinopeptide A; Fibrinopeptide B; Humans; Platelet Aggregation; Serotonin | 1980 |
Fibrinogen receptor exposure and aggregation of human blood platelets produced by ADP and chilling.
Topics: Adenosine Diphosphate; Antimycin A; Binding Sites; Body Temperature; Cold Temperature; Deoxyglucose; Fibrinogen; Filtration; Formaldehyde; Humans; Hydrogen-Ion Concentration; Platelet Aggregation | 1981 |
Regulation of platelet aggregation by post-fibrinogen binding events. Insights provided by dithiothreitol-treated platelets.
Topics: Adenosine Diphosphate; Blood Platelets; Dithiothreitol; Edetic Acid; Fibrinogen; Humans; Microscopy, Confocal; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding | 1995 |
In vivo degradation of human fibrinogen A alpha: detection of cleavage sites and release of antithrombotic peptides.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Binding Sites; Blood Platelets; Fibrinogen; Fibrinolysin; Fibrinopeptide A; Humans; Molecular Sequence Data; Oligopeptides; Platelet Aggregation; Platelet Aggregation Inhibitors | 1995 |
Regulation of platelet activation in vitro by the c-Mpl ligand, thrombopoietin.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Blood Platelets; Fibrinogen; Humans; In Vitro Techniques; Megakaryocytes; Molecular Sequence Data; Neoplasm Proteins; Oligopeptides; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Platelet Activation; Platelet Aggregation; Proto-Oncogene Proteins; Receptors, Cytokine; Receptors, Immunologic; Receptors, Thrombopoietin; Thrombopoietin; Tyrosine | 1995 |
Epinephrine sensitizes human platelets in vivo and in vitro as studied by fibrinogen binding and P-selectin expression.
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Calcium; Dose-Response Relationship, Drug; Epinephrine; Fibrinogen; Humans; Male; P-Selectin; Platelet Activation; Platelet Membrane Glycoproteins | 1994 |
Temperature and risk factors for ischaemic heart disease in the Caerphilly prospective study.
Topics: Adenosine Diphosphate; Aged; alpha-Macroglobulins; Blood Platelets; Blood Pressure; Cholesterol, HDL; Cold Temperature; Fibrinogen; Hemostatics; Humans; Male; Middle Aged; Myocardial Ischemia; Platelet Count; Prospective Studies; Risk Factors; Wales | 1993 |
Antiplatelet effects of a novel antianginal agent, nicorandil.
Topics: Acetylcysteine; Adenosine Diphosphate; Analysis of Variance; Binding Sites; Blood Platelets; Cyclic GMP; Dose-Response Relationship, Drug; Drug Tolerance; Fibrinogen; Guanylate Cyclase; Humans; Niacinamide; Nicorandil; Platelet Aggregation; Platelet Aggregation Inhibitors; Potassium Channels; Radioimmunoassay; Vasodilator Agents | 1994 |
Quantitation of soluble fibrinogen binding to platelets by fluorescence-activated flow cytometry.
Topics: Adenosine Diphosphate; Binding Sites; Blood Platelets; Electrophoresis, Polyacrylamide Gel; Fibrinogen; Flow Cytometry; Fluorescein-5-isothiocyanate; Humans; Integrins; Platelet Glycoprotein GPIIb-IIIa Complex; Receptors, Cytoadhesin; Solubility | 1994 |
ADP causes partial degranulation of platelets in the absence of aggregation.
Topics: Adenosine Diphosphate; Antigens, CD; beta-Thromboglobulin; Blood Platelets; Cell Degranulation; Fibrinogen; Flow Cytometry; Humans; P-Selectin; Platelet Aggregation; Platelet Membrane Glycoproteins; Tetraspanin 30; Thrombin | 1994 |
Impaired function of platelet membrane glycoprotein IIb-IIIa in end-stage renal disease.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Antibodies, Monoclonal; Epitopes; Erythropoietin; Female; Fibrinogen; Flow Cytometry; Hemorrhagic Disorders; Humans; Kidney Failure, Chronic; Male; Molecular Sequence Data; Oligopeptides; Platelet Aggregation; Platelet Membrane Glycoproteins; Protein Binding; Protein Conformation; Recombinant Proteins; Renal Dialysis; Tetradecanoylphorbol Acetate | 1994 |
Streptokinase and rt-PA activate platelets by a different way: implications on the rethrombosis rate after their administration in myocardial infarction.
Topics: Adenosine Diphosphate; beta-Thromboglobulin; Blood Platelets; Cell Adhesion Molecules; Fibrinogen; Flow Cytometry; Humans; Myocardial Infarction; P-Selectin; Plasminogen Activator Inhibitor 1; Plasminogen Activators; Platelet Activation; Platelet Membrane Glycoproteins; Recombinant Proteins; Recurrence; Serotonin; Streptokinase; Thrombin; Thrombolytic Therapy; Thromboxane A2 | 1995 |
Aspirin does not affect the flow cytometric detection of fibrinogen binding to, or release of alpha-granules or lysosomes from, human platelets.
Topics: Adenosine Diphosphate; Adult; Antigens, CD; Aspirin; Blood Platelets; Cell Degranulation; Dose-Response Relationship, Drug; Drug Interactions; Fibrinogen; Flow Cytometry; Humans; Male; P-Selectin; Platelet Activation; Platelet Aggregation; Platelet Membrane Glycoproteins; Tetraspanin 30; Thrombin | 1994 |
Recombinant human megakaryocyte growth and development factor (rHuMGDF), a ligand for c-Mpl, produces functional human platelets in vitro.
Topics: Adenosine Diphosphate; Antigens, CD; Antigens, CD34; Blood Platelets; Cell Differentiation; Cells, Cultured; Fibrinogen; Hematopoiesis; Hematopoietic Stem Cells; Humans; Megakaryocytes; Platelet Activation; Platelet Aggregation; Platelet Membrane Glycoproteins; Quinacrine; Recombinant Proteins; Thrombopoietin | 1995 |
[Evaluation, by flow cytometry, of activated platelet levels after coronarography and intraluminal angioplasty].
Topics: Adenosine Diphosphate; Adult; Aged; Angioplasty, Balloon; Aspirin; Coronary Angiography; Female; Fibrinogen; Flow Cytometry; Humans; Male; Middle Aged; Platelet Activation; Platelet Count | 1995 |
Inhibition of ADP-induced platelet responses by covalent modification of aggregin, a putative ADP receptor, by 8-(4-bromo-2,3-dioxobutylthio)ADP.
Topics: Adenosine Diphosphate; Affinity Labels; Autoradiography; Binding Sites; Blood Platelets; Calcimycin; Electrophoresis, Polyacrylamide Gel; Fibrinogen; Humans; In Vitro Techniques; Ionophores; Kinetics; Molecular Structure; Molecular Weight; Phosphorus Radioisotopes; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Receptors, Purinergic P2; Thionucleotides; Thrombin | 1995 |
Surface recruitment but not activation of integrin alpha IIb beta 3 (GPIIb-IIIa) requires a functional actin cytoskeleton.
Topics: Actins; Adenosine Diphosphate; Binding Sites; Blood Platelets; Cytochalasin D; Cytoplasmic Granules; Cytoskeleton; Fibrinogen; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Platelet Aggregation; Platelet Membrane Glycoproteins; Protein Conformation | 1995 |
An inherited bleeding disorder linked to a defective interaction between ADP and its receptor on platelets. Its influence on glycoprotein IIb-IIIa complex function.
Topics: Adenosine Diphosphate; Alprostadil; Blood Coagulation Disorders; Blood Platelets; Cyclic AMP; Cytoplasmic Granules; Epinephrine; Fibrinogen; Flow Cytometry; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptors, Purinergic P2; Thionucleotides; White People | 1995 |
Antiplatelet actions of 2-(4-[1-(2-chlorophenyl) piperazinyl]) methyl-2,3-dihydroimidazo[1,2-c]quinazolin-5(6H)-one compound.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Blood Platelets; Calcium; Collagen; Cyclic AMP; Epinephrine; Fibrinogen; Humans; Imidazoles; Pancreatic Elastase; Phosphatidylinositols; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Quinazolines; Rabbits; Receptors, Cell Surface; Signal Transduction; Thromboxane A2; Thromboxane B2 | 1995 |
Protein kinase C activation is not a key step in ADP-mediated exposure of fibrinogen receptors on human platelets.
Topics: Adenosine Diphosphate; Blood Platelets; Blood Proteins; Calcium; Enzyme Activation; Fibrinogen; Humans; Indoles; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Protein Kinase C | 1995 |
Whole-blood platelet aggregation predicts in vitro and in vivo primary hemostatic function in the elderly.
Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Aging; Arachidonic Acid; Arteries; Bleeding Time; Collagen; Endothelium, Vascular; Factor VIIa; Female; Fibrinogen; Hemostasis; Humans; Male; Multivariate Analysis; Platelet Aggregation; Sex Characteristics | 1995 |
Synthetic peptides demonstrate RGD-independent platelet glycoprotein IIb/IIIa recognition site in cell binding domain of human fibronectin.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Binding Sites; Binding, Competitive; Blood Platelets; Fibrinogen; Fibronectins; Humans; Molecular Sequence Data; Oligopeptides; Peptide Fragments; Platelet Aggregation; Platelet Membrane Glycoproteins | 1995 |
Fibrinogen binding is independent of an increase in intracellular calcium concentration in thrombin degranulated platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Blood Platelets; Calcium; Cell Degranulation; Evaluation Studies as Topic; Fibrinogen; Humans; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Protein Binding; Receptors, Thromboxane; Thromboxane A2; Thromboxanes | 1995 |
Adherent platelet morphology on adsorbed fibrinogen: effects of protein incubation time and albumin addition.
Topics: Adenosine Diphosphate; Adsorption; Analysis of Variance; Biocompatible Materials; Blood Platelets; Fibrinogen; Fluorescein-5-isothiocyanate; Humans; In Vitro Techniques; Methylmethacrylates; Platelet Adhesiveness; Platelet Aggregation; Serum Albumin; Time Factors | 1994 |
Properties of fibrinogen cleaved by Jararhagin, a metalloproteinase from the venom of Bothrops jararaca.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Animals; Bothrops; Bothrops jararaca Venom; Crotalid Venoms; Fibrin Fibrinogen Degradation Products; Fibrinogen; Fibrinopeptide A; Hemostasis; Humans; Metalloendopeptidases; Molecular Sequence Data; Oligopeptides; Platelet Aggregation | 1994 |
Dynamics of platelet glycoprotein IIb-IIIa receptor expression and fibrinogen binding. I. Quantal activation of platelet subpopulations varies with adenosine diphosphate concentration.
Topics: Adenosine Diphosphate; Adult; Antibodies, Monoclonal; Biophysical Phenomena; Biophysics; Blood Platelets; Female; Fibrinogen; Flow Cytometry; Fluorescein-5-isothiocyanate; Humans; In Vitro Techniques; Kinetics; Male; Middle Aged; Platelet Activation; Platelet Membrane Glycoproteins | 1994 |
Dynamics of platelet glycoprotein IIb-IIIa receptor expression and fibrinogen binding. II. Quantal activation parallels platelet capture in stir-associated microaggregation.
Topics: Adenosine Diphosphate; Adult; Antibodies, Monoclonal; Biophysical Phenomena; Biophysics; Blood Platelets; Female; Fibrinogen; Flow Cytometry; Fluorescein-5-isothiocyanate; Humans; In Vitro Techniques; Kinetics; Male; Middle Aged; Platelet Activation; Platelet Aggregation; Platelet Count; Platelet Membrane Glycoproteins | 1994 |
Characterization of adhesion of non-exogenously stimulated and resting platelets in normal plasma to fibrinogen and its fragments.
Topics: Adenosine Diphosphate; Alprostadil; Amino Acid Sequence; Binding Sites; Blood; Blood Platelets; Calcium; Citrates; Citric Acid; Fibrinogen; Humans; Hydrogen-Ion Concentration; Microscopy, Electron, Scanning; Molecular Sequence Data; Peptide Fragments; Platelet Activation; Platelet Adhesiveness | 1994 |
Enhancement of platelet aggregation in patients with nasopharyngeal carcinoma.
Topics: Adenosine Diphosphate; Carcinoma; Female; Fibrinogen; Humans; Male; Nasopharyngeal Neoplasms; Nasopharynx; Neoplasm Staging; Platelet Aggregation; Platelet Count; Treatment Outcome | 1994 |
Fluorescein derivatization of fibrinogen for flow cytometric analysis of fibrinogen binding to platelets.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Cellular Senescence; Dogs; Edetic Acid; Fibrinogen; Flow Cytometry; Fluoresceins; Humans; Platelet Activating Factor; Platelet Activation | 1994 |
Factor XIIIa binding to activated platelets is mediated through activation of glycoprotein IIb-IIIa.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Antibodies, Monoclonal; Antigens, CD; Arachidonic Acid; Blood Platelets; Calcimycin; Collagen; Epinephrine; Fibrinogen; Fibronectins; Flow Cytometry; Humans; In Vitro Techniques; Kinetics; Membrane Glycoproteins; Membrane Proteins; Oligopeptides; Platelet Activation; Platelet Membrane Glycoproteins; Reference Values; Tetradecanoylphorbol Acetate; Thrombasthenia; Thrombin; Thrombospondins; Time Factors; Transglutaminases | 1994 |
"Bridged" peptide of fibrinogen binds to platelets activated by RGD peptide as well as by ADP.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Antibodies, Monoclonal; Blood Platelets; Evaluation Studies as Topic; Fibrinogen; Humans; Iodine Radioisotopes; Molecular Sequence Data; Oligopeptides; Peptides; Platelet Activation; Platelet Membrane Glycoproteins; Protein Binding; Stimulation, Chemical | 1994 |
Biotinylated fibrinogen. A novel probe for monitoring post-ligand-binding events in platelets.
Topics: Adenosine Diphosphate; Biotin; Blood Platelets; Fibrinogen; Humans; Microscopy, Electron; Platelet Adhesiveness; Platelet Aggregation; Platelet Membrane Glycoproteins | 1994 |
Flow cytometric detection of circulating activated platelets and platelet hyper-responsiveness in pre-eclampsia and pregnancy.
Topics: Adenosine Diphosphate; Adult; Antigens, CD; beta-Thromboglobulin; Blood Platelets; Enzyme-Linked Immunosorbent Assay; Female; Fibrinogen; Flow Cytometry; Humans; Platelet Activation; Platelet Membrane Glycoproteins; Pre-Eclampsia; Pregnancy; Proteinuria; Tetraspanin 30 | 1994 |
Stabilization of platelet-fibrinogen interactions is an integral property of the glycoprotein IIb-IIIa complex.
Topics: Adenosine Diphosphate; Alprostadil; Antibodies, Monoclonal; Blood Platelets; Chromatography, Affinity; Chromatography, Gel; Drug Interactions; Drug Stability; Edetic Acid; Fibrinogen; Humans; Platelet Membrane Glycoproteins; Time Factors | 1994 |
Effect of plasma fibrinogen concentration on the inhibition of platelet aggregation after ticlopidine compared with aspirin.
Topics: Adenosine Diphosphate; Aged; Aspirin; Cerebral Infarction; Cerebrovascular Disorders; Collagen; Female; Fibrinogen; Humans; Male; Platelet Aggregation; Platelet Count; Ticlopidine | 1994 |
Effect of single oral dose of aspirin on human platelet functions and plasma plasminogen activator inhibitor-1.
Topics: Adenosine Diphosphate; Arachidonic Acid; Aspirin; Blood Platelets; Epinephrine; Female; Fibrinogen; Humans; In Vitro Techniques; Male; Plasminogen Activator Inhibitor 1; Platelet Aggregation; Time Factors | 1993 |
Adenosine diphosphate-induced aggregation of human platelets in flow through tubes: III. Shear and extrinsic fibrinogen-dependent effects.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Calcium; Fibrinogen; Flow Cytometry; Hematology; Humans; Immunoglobulin Fab Fragments; Molecular Sequence Data; Oligopeptides; Platelet Activation; Platelet Aggregation; Rheology; Stress, Mechanical; Temperature | 1994 |
Expression of fibrinogen receptors on platelets of uremic patients is correlated with the content of GPIIb and plasma level of creatinine.
Topics: Adenosine Diphosphate; Adult; beta-Thromboglobulin; Blood Platelets; Creatinine; Female; Fibrinogen; Humans; In Vitro Techniques; Male; Middle Aged; Platelet Activation; Platelet Membrane Glycoproteins; Uremia | 1994 |
Platelets from bleeding Simmental cattle mobilize calcium, phosphorylate myosin light chain and bind normal numbers of fibrinogen molecules but have abnormal cytoskeletal assembly and aggregation in response to ADP.
Topics: Adenosine Diphosphate; Animals; Blood Coagulation Disorders; Blood Platelets; Calcimycin; Calcium; Cattle; Cattle Diseases; Cytoskeleton; Cytosol; Fibrinogen; In Vitro Techniques; Ionomycin; Male; Microscopy, Electron; Myosins; Phosphorylation; Platelet Aggregation; Platelet Membrane Glycoproteins; Tetradecanoylphorbol Acetate | 1994 |
Ex-vivo and in-vivo antithrombotic effect of triflavin, an RGD-containing peptide.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Animals; Blood Platelets; Crotalid Venoms; Fibrinogen; Fibrinolytic Agents; Humans; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Iodine Radioisotopes; Mice; Mice, Inbred ICR; Molecular Sequence Data; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Pulmonary Embolism; Rabbits | 1994 |
Platelet aggregation and fibrinogen binding in human, rhesus monkey, guinea-pig, hamster and rat blood: activation by ADP and a thrombin receptor peptide and inhibition by glycoprotein IIb/IIIa antagonists.
Topics: Adenosine Diphosphate; Animals; Cricetinae; Fibrinogen; Flow Cytometry; Guinea Pigs; Humans; Macaca mulatta; Peptide Fragments; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Protein Binding; Rats; Species Specificity | 1993 |
LDLs increase the exposure of fibrinogen binding sites on platelets and secretion of dense granules.
Topics: Adenosine Diphosphate; Binding Sites; Blood Platelets; Cytoplasmic Granules; Fibrinogen; Humans; Indomethacin; Lipoproteins, HDL; Lipoproteins, LDL; Lysine; Platelet Aggregation; Platelet Membrane Glycoproteins; Serotonin; Thrombin | 1994 |
Blood coagulability and hematological changes in calves with chronic centrifugal biventricular bypass pumps.
Topics: Adenosine Diphosphate; Animals; Blood Coagulation; Cattle; Collagen; Fibrinogen; Heart-Assist Devices; Heparin; Partial Thromboplastin Time; Platelet Aggregation; Platelet Count; Postoperative Period; Prothrombin Time; Pulmonary Embolism; Time Factors | 1994 |
Increased platelet-fibrinogen interaction in patients with hypercholesterolemia and hypertriglyceridemia.
Topics: Adenosine Diphosphate; Adult; Aged; Binding Sites; Blood Platelets; Cholesterol; Female; Fibrinogen; Humans; Hypercholesterolemia; Hypertriglyceridemia; Lipoproteins, HDL; Lipoproteins, LDL; Male; Middle Aged; Palmitic Acid; Palmitic Acids; Platelet Membrane Glycoproteins | 1993 |
Thrombus formation and platelet-vessel wall interaction in the nephrotic syndrome under flow conditions.
Topics: Adenosine Diphosphate; Adolescent; Adult; Angiotensin III; Arachidonic Acid; Biopsy; Blood Coagulation Factors; Blood Platelets; Collagen; Endothelium, Vascular; Erythrocyte Deformability; Extracellular Matrix; Female; Fibrin; Fibrinogen; Humans; In Vitro Techniques; Kidney; Male; Microscopy, Electron, Scanning; Middle Aged; Muscle, Smooth, Vascular; Nephrotic Syndrome; Platelet Adhesiveness; Platelet Aggregation; Thrombosis; Umbilical Arteries | 1994 |
Tetrafibricin: a nonpeptidic fibrinogen receptor inhibitor from Streptomyces neyagawaensis (I). Its GPIIb/IIIa blockage on solid phase binding assay.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Anti-Bacterial Agents; Binding, Competitive; Blood Platelets; Fibrinogen; Humans; In Vitro Techniques; Macrolides; Molecular Sequence Data; Oligopeptides; Platelet Membrane Glycoproteins; Streptomyces; von Willebrand Factor | 1993 |
Tetrafibricin: a nonpeptidic fibrinogen receptor inhibitor from Streptomyces neyagawaensis. (II). Its antiplatelet activities.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Animals; Anti-Bacterial Agents; Blood Platelets; Cattle; Cell Degranulation; Chymotrypsin; Fibrinogen; Humans; In Vitro Techniques; Macrolides; Molecular Sequence Data; Oligopeptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Serotonin; Streptomyces | 1993 |
Increased whole blood platelet aggregation in patients with Raynaud's phenomenon with or without systemic sclerosis.
Topics: Adenosine Diphosphate; Adult; Aged; Collagen; Female; Fibrinogen; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation; Platelet Count; Raynaud Disease; Scleroderma, Systemic | 1993 |
Hemostasis variables in type I diabetic patients without demonstrable vascular complications.
Topics: Adenosine Diphosphate; Adult; Blood Coagulation Factors; Blood Pressure; Blood Viscosity; C-Peptide; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Collagen; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Female; Fibrinogen; Glycated Hemoglobin; Hemostasis; Humans; Male; Platelet Aggregation; Platelet Count; Reference Values; Triglycerides | 1993 |
Antiplatelet properties of protein S-nitrosothiols derived from nitric oxide and endothelium-derived relaxing factor.
Topics: Adenosine Diphosphate; Animals; Bleeding Time; Blood Coagulation; Blood Platelets; Blood Proteins; Collagen; Cyclic GMP; Cysteine; Dogs; Fibrinogen; Glutathione; Humans; Molecular Weight; Nitric Oxide; Nitroso Compounds; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Binding; S-Nitrosoglutathione; S-Nitrosothiols; Time Factors | 1993 |
Bubble-induced aggregation of platelets: effects of gas species, proteins, and decompression.
Topics: Adenosine Diphosphate; Albumins; Blood Platelets; Cyclic AMP; Embolism, Air; Fibrinogen; Helium; Humans; Microscopy, Electron, Scanning; Nitrogen; Noble Gases; Platelet Aggregation; Platelet Count; Pressure | 1993 |
ADP-stimulated fibrinogen binding is necessary for some of the inositol phospholipid changes found in ADP-stimulated platelets.
Topics: Adenosine Diphosphate; Blood Platelets; Fibrinogen; Humans; In Vitro Techniques; Oligopeptides; Phosphatidic Acids; Phosphatidylinositols; Platelet Aggregation; Platelet Aggregation Inhibitors | 1993 |
Salivary gland extracts from the deerfly contain a potent inhibitor of platelet aggregation.
Topics: Adenosine Diphosphate; Animals; Apyrase; Blood Platelets; Cell Separation; Cyclic AMP; Cyclic GMP; Diptera; Electrophoresis, Polyacrylamide Gel; Fibrinogen; Humans; Kinetics; Molecular Weight; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Salivary Glands; Salivary Proteins and Peptides; Tissue Extracts | 1993 |
Roles of phospholipase C and Ca(2+)-ATPase in calcium responses of single, fibrinogen-bound platelets.
Topics: Adenosine Diphosphate; Apyrase; Aspirin; Blood Platelets; Calcium; Calcium-Transporting ATPases; Cytosol; Egtazic Acid; Fibrinogen; Fura-2; Humans; Inositol Phosphates; Kinetics; Platelet Activation; Spectrometry, Fluorescence; Terpenes; Thapsigargin; Thrombin; Type C Phospholipases; Video Recording | 1993 |
Beta 3 integrin derived peptide 217-230 inhibits fibrinogen binding and platelet aggregation: significance of RGD sequences and fibrinogen A alpha-chain.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Blood Platelets; Crotalid Venoms; Fibrinogen; Humans; In Vitro Techniques; Kinetics; Molecular Sequence Data; Peptide Fragments; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Snake Venoms | 1993 |
Stabilization of platelet-fibrinogen interactions: modulation by divalent cations.
Topics: Adenosine Diphosphate; Blood Platelets; Cations, Divalent; Clot Retraction; Drug Resistance; Edetic Acid; Fibrinogen; Humans; Manganese; Platelet Aggregation; Thrombin | 1993 |
Exposure of platelet fibrinogen receptors by zinc ions: role of protein kinase C.
Topics: Adenosine Diphosphate; Alkaloids; Blood Platelets; Drug Synergism; Egtazic Acid; Electrophoresis, Polyacrylamide Gel; Fibrinogen; Humans; In Vitro Techniques; Molecular Weight; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Membrane Glycoproteins; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Trifluoperazine; Zinc | 1993 |
Fibrinogen internalization by ADP-stimulated blood platelets. Ultrastructural studies with fibrinogen-colloidal gold probes.
Topics: Adenosine Diphosphate; Blood Platelets; Cell Size; Fibrinogen; Gold; Humans; Platelet Activation | 1993 |
RGD-containing peptides inhibit adhesion of 293 cells transfected with GpIIb/IIIa to fibrinogen: comparison to inhibition of platelet aggregation.
Topics: Adenosine Diphosphate; Antibodies, Monoclonal; Biological Assay; Calcium; Cell Adhesion; Clone Cells; Edetic Acid; Egtazic Acid; Fibrinogen; Humans; Magnesium; Models, Biological; Oligopeptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Recombinant Proteins; Transfection | 1993 |
Protein kinase C regulates tyrosine phosphorylation of pp125FAK in platelets adherent to fibrinogen.
Topics: Adenosine Diphosphate; Apyrase; Blood Platelets; Calcium; Cell Adhesion Molecules; Cell Size; Egtazic Acid; Enzyme Inhibitors; Fibrinogen; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Indoles; Maleimides; Phosphoproteins; Phosphorylation; Platelet Adhesiveness; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Kinase C; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Signal Transduction; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Tyrosine | 1996 |
Sequence 274-368 in the beta 3-subunit of the integrin alpha IIb beta 3 provides a ligand recognition and binding domain for the gamma-chain of fibrinogen that is independent of platelet activation.
Topics: Adenosine Diphosphate; Alprostadil; Amino Acid Sequence; Antibodies, Monoclonal; Binding Sites; Egtazic Acid; Fibrinogen; Humans; Ligands; Molecular Sequence Data; Oligopeptides; Peptide Fragments; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Recombinant Fusion Proteins; Thrombin | 1996 |
Internalization of bound fibrinogen modulates platelet aggregation.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Cell Compartmentation; Endocytosis; Fibrinogen; Flow Cytometry; Humans; Microscopy, Fluorescence; Molecular Sequence Data; Peptide Fragments; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Zinc | 1996 |
Monamidocin, a novel fibrinogen receptor antagonist. II. Biological activity and structure-activity relationships.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Collagen; Fibrinogen; Humans; Molecular Sequence Data; Molecular Structure; Phenylalanine; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Streptomyces; Structure-Activity Relationship; Thrombin; Tyrosine | 1995 |
Platelet activation and thrombosis: studies in a patient with essential thrombocythemia.
Topics: Adenosine Diphosphate; Adult; Antibodies, Monoclonal; Aspirin; Blood Platelets; Disease Susceptibility; Female; Fibrinogen; Flow Cytometry; Humans; Mesenteric Arteries; Mesenteric Vascular Occlusion; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Portal Vein; Receptors, Purinergic P2; Splenic Vein; Thrombocythemia, Essential; Thrombosis; Ticlopidine | 1996 |
Dissecting clot retraction and platelet aggregation. Clot retraction does not require an intact fibrinogen gamma chain C terminus.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Blood Platelets; Clot Retraction; Fibrinogen; Humans; Molecular Sequence Data; Platelet Aggregation; Sequence Deletion; Structure-Activity Relationship | 1996 |
Thrombin-induced platelet aggregation is inhibited by the heptapeptide Leu271-Ala277 of domain 3 in the heavy chain of high molecular weight kininogen.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Base Sequence; Collagen; Exons; Fibrinogen; Humans; In Vitro Techniques; Kinetics; Kininogens; Macromolecular Substances; Models, Molecular; Molecular Sequence Data; Oligodeoxyribonucleotides; Peptide Fragments; Plasmids; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Conformation; Recombinant Fusion Proteins; Recombinant Proteins; Sequence Deletion; Structure-Activity Relationship; Thrombin | 1996 |
A comparative study of the effect of autologous platelet-rich plasma and fresh autologous whole blood on haemostasis after cardiac surgery.
Topics: Adenosine Diphosphate; Adult; Blood Loss, Surgical; Blood Transfusion; Blood Transfusion, Autologous; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Elective Surgical Procedures; Factor VIII; Female; Fibrinogen; Hemostasis, Surgical; Heparin Antagonists; Humans; Male; Middle Aged; Plasma; Platelet Aggregation; Platelet Count; Platelet Transfusion; Prospective Studies | 1996 |
Relative reactivity of platelets from thrombopoietin- and interleukin-6-treated dogs.
Topics: Adenosine Diphosphate; Animals; Benzothiazoles; Blood Platelets; Coloring Agents; Dogs; Fibrinogen; Flow Cytometry; Hematopoiesis; Interleukin-6; Megakaryocytes; P-Selectin; Platelet Activation; Quinolines; Recombinant Proteins; Thiazoles; Thrombin; Thrombopoietin | 1996 |
Platelet aggregation is inhibited by phycolectins.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Collagen; Dose-Response Relationship, Drug; Fibrinogen; Hemagglutinins; Humans; Lectins; Molecular Sequence Data; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Rhodophyta | 1996 |
Distribution of ligand-occupied alpha IIb beta 3 in resting and activated human platelets determined by expression of a novel class of ligand-induced binding site recognized by monoclonal antibody AP6.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Antibodies, Monoclonal; Antibody Specificity; Antigens, Surface; Binding Sites; Biological Transport; Blood Platelets; Cytoplasmic Granules; Fibrinogen; Humans; Immunohistochemistry; Ligands; Microscopy, Immunoelectron; Molecular Sequence Data; Oligopeptides; P-Selectin; Peptide Fragments; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombin | 1996 |
Inhibition of ADP-induced platelet activation by 7-chloro-4-nitrobenz-2-oxa-1,3-diazole: covalent modification of aggregin, a putative ADP receptor.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 4-Chloro-7-nitrobenzofurazan; Adenosine; Adenosine Diphosphate; Blood Platelets; Calcimycin; Calcium; Cell Aggregation; Cell Size; Collagen; Cyclic AMP; Fibrinogen; Humans; Platelet Activation; Platelet Membrane Glycoproteins; Prostaglandin Endoperoxides, Synthetic; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2; Time Factors | 1996 |
Platelet lysis and functional perturbation by 13-methyl myristate. The major fatty acid in Flavobacterium ranacida.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Blood Platelets; Cattle; Cell Membrane; Collagen; Fibrinogen; Flavobacterium; Humans; Microscopy, Electron, Scanning; Myristic Acids; Platelet Activation; Prostaglandin Endoperoxides, Synthetic; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2 | 1996 |
alphaIIb beta 3-integrin mediated adhesion of human platelets to a fibrinogen matrix triggers phospholipase C activation and phosphatidylinositol 3',4'-biphosphate accumulation.
Topics: Adenosine Diphosphate; Blood Platelets; Cyclooxygenase Inhibitors; Enzyme Activation; Extracellular Matrix; Fibrinogen; Humans; Phosphatidylinositol 3-Kinases; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phosphotransferases (Alcohol Group Acceptor); Platelet Adhesiveness; Platelet Glycoprotein GPIIb-IIIa Complex; Type C Phospholipases | 1996 |
Interspecies comparison of platelet aggregation, LIBS expression and clot retraction: observed differences in GPIIb-IIIa functional activity.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Clot Retraction; Dogs; Fibrinogen; Haplorhini; Humans; Molecular Sequence Data; Oligopeptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Conformation; Rabbits; Species Specificity; Swine | 1995 |
Identification of haptoglobin as an alternative ligand for CD11b/CD18.
Topics: Adenosine Diphosphate; Antibodies, Monoclonal; Calcium; CD18 Antigens; Cell Line; Fibrinogen; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Granulocytes; Haptoglobins; Humans; In Vitro Techniques; Killer Cells, Natural; Kinetics; Ligands; Lymphocytes; Macrophage-1 Antigen; Monocytes; Protein Binding; T-Lymphocyte Subsets; Temperature | 1996 |
Platelets from bleeding Simmental cattle have a long delay in both ADP-activated expression of GpIIB-IIIA receptors and fibrinogen-dependent platelet aggregation.
Topics: Adenosine Diphosphate; Animals; Blood Platelet Disorders; Cattle; Cattle Diseases; Fibrinogen; Hemorrhage; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex | 1996 |
Antithrombotic effect in vivo of thrombotic substances adsorbed on a platinum surface.
Topics: Adenosine Diphosphate; Adsorption; Albumins; Animals; Arachidonic Acid; Biocompatible Materials; Catheterization; Collagen; Female; Fibrinogen; Male; Platelet Activation; Platinum; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Surface Properties; Thrombin; Thrombosis; Venae Cavae | 1996 |
Interaction of beta 3 integrin-derived peptides 214-218 and 217-231 with alpha IIb beta 3 complex and with fibrinogen A alpha-chain.
Topics: Adenosine Diphosphate; Antigens, CD; Blood Platelets; Enzyme-Linked Immunosorbent Assay; Fibrinogen; Humans; Integrin beta3; Integrins; Peptide Fragments; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Membrane Glycoproteins | 1997 |
Surface-secreted von Willebrand factor mediates aggregation of ADP-activated platelets at moderate shear stress: facilitated by GPIb but controlled by GPIIb-IIIa.
Topics: Adenosine Diphosphate; Antibodies, Monoclonal; Blood Platelets; Fibrinogen; Flow Cytometry; Humans; Platelet Activation; Platelet Aggregation; Platelet Glycoprotein GPIb-IX Complex; Platelet Glycoprotein GPIIb-IIIa Complex; Surface Properties; von Willebrand Factor | 1997 |
Agonist-activated alphavbeta3 on platelets and lymphocytes binds to the matrix protein osteopontin.
Topics: Adenosine Diphosphate; Angioplasty, Balloon, Coronary; Blood Platelets; Calcium; Cell Adhesion; Cytokines; Fibrinogen; Humans; Lymphocytes; Magnesium; Osteopontin; Phosphoproteins; Platelet Adhesiveness; Receptors, Vitronectin; Recombinant Proteins; Sialoglycoproteins | 1997 |
Tyrosine phosphorylation of the novel protein-tyrosine kinase RAFTK during an early phase of platelet activation by an integrin glycoprotein IIb-IIIa-independent mechanism.
Topics: Adenosine Diphosphate; Blood Platelets; Calcimycin; Collagen; Cytochalasin D; Epinephrine; Fibrinogen; Focal Adhesion Kinase 2; Humans; In Vitro Techniques; Kinetics; Phosphorylation; Phosphotyrosine; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein-Tyrosine Kinases; Thrombin | 1997 |
In vitro effects of rt-PA on platelet function and clot strength.
Topics: Adenosine Diphosphate; Blood Coagulation; Blood Platelets; Collagen; Fibrin Fibrinogen Degradation Products; Fibrinogen; Humans; In Vitro Techniques; Plasminogen; Platelet Aggregation; Recombinant Proteins; Thrombelastography; Tissue Plasminogen Activator | 1997 |
Isolation and amino acid sequence of flavostatin, a novel disintegrin from the venom of Trimeresurus flavoviridis.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Animals; Chromatography, High Pressure Liquid; Collagen; Crotalid Venoms; Disintegrins; Electrophoresis, Polyacrylamide Gel; Fibrinogen; Intercellular Signaling Peptides and Proteins; Molecular Sequence Data; Oligopeptides; Peptide Fragments; Peptides; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Receptors, Thrombin; Sequence Analysis; Sequence Homology, Amino Acid | 1997 |
High shear stress attenuates agonist-induced, glycoprotein IIb/IIIa-mediated platelet aggregation when von Willebrand factor binding to glycoprotein Ib/IX is blocked.
Topics: Adenosine Diphosphate; Animals; Antibodies, Monoclonal; Fibrinogen; Humans; In Vitro Techniques; Mice; Platelet Aggregation; Platelet Glycoprotein GPIb-IX Complex; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Stress, Mechanical; von Willebrand Factor | 1997 |
Deficiency of (33P)2MeS-ADP binding sites on platelets with secretion defect, normal granule stores and normal thromboxane A2 production. Evidence that ADP potentiates platelet secretion independently of the formation of large platelet aggregates and thro
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adult; Binding Sites; Blood Platelet Disorders; Blood Platelets; Cytoplasmic Granules; Female; Fibrinogen; Humans; In Vitro Techniques; Kinetics; Male; Middle Aged; Phosphorus Radioisotopes; Platelet Aggregation; Reference Values; Serotonin; Thionucleotides; Thromboxane A2 | 1997 |
Non-peptide glycoprotein IIb/IIIa inhibitors. 17. Design and synthesis of orally active, long-acting non-peptide fibrinogen receptor antagonists.
Topics: Adenosine Diphosphate; Animals; Azepines; Blood Platelets; Collagen; Dogs; Endothelium, Vascular; Fibrinogen; Fibrinolytic Agents; Fibronectins; Humans; Molecular Structure; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Structure-Activity Relationship; Sulfonamides; Vitronectin | 1997 |
Characterization of the interaction between the Staphylococcus aureus clumping factor (ClfA) and fibrinogen.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Bacterial Adhesion; Bacterial Proteins; Binding Sites; Carrier Proteins; Fibrinogen; Molecular Sequence Data; Platelet Adhesiveness; Platelet Aggregation; Staphylococcus aureus | 1997 |
Colocalization of gold-labeled LDL and fibrinogen on platelets: enhanced fibrinogen binding induced by LDL.
Topics: Adenosine Diphosphate; Binding Sites; Binding, Competitive; Blood Platelets; Cell Membrane; Fibrinogen; Gold Colloid; Humans; In Vitro Techniques; Kinetics; Lipoproteins, LDL; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Receptors, LDL; Substrate Specificity | 1997 |
Detection of activated platelets and platelet-leukocyte aggregates in horses.
Topics: Adenosine Diphosphate; Analysis of Variance; Animals; Blood Platelets; Cell Aggregation; Erythrocytes; Fibrinogen; Flow Cytometry; Horses; Humans; Leukocytes; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Platelet Count; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombin | 1997 |
The in vitro and in vivo pharmacological profiles of a platelet glycoprotein IIb/IIIa antagonist, NSL-9403.
Topics: Adenosine Diphosphate; Animals; Bleeding Time; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Femoral Artery; Fibrinogen; Humans; Male; Mice; Oligopeptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pulmonary Embolism; Thrombosis | 1997 |
New orally active non-peptide fibrinogen receptor (GpIIb-IIIa) antagonists: identification of ethyl 3-[N-[4-[4-[amino[(ethoxycarbonyl) imino]methyl]phenyl]-1,3-thiazol-2-yl]-N-[1-[(ethoxycarbonyl)methyl]pip erid -4-yl]amino]propionate (SR 121787) as a pot
Topics: Adenosine Diphosphate; Administration, Oral; Animals; Benzylamines; Fibrinogen; Fibrinolytic Agents; Humans; Molecular Structure; Papio; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Thiazoles | 1997 |
Characterization of human platelet IgG Fc receptor associated with membrane glycoprotein.
Topics: Adenosine Diphosphate; Antigen-Antibody Complex; Binding Sites; Blood Platelets; Fibrinogen; Humans; Immunoglobulin G; In Vitro Techniques; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Membrane Glycoproteins; Protein Binding; Receptors, IgG; Trypsin | 1995 |
Hydrodynamic effects and receptor interactions of platelets and their aggregates in linear shear flow.
Topics: Adenosine Diphosphate; Antigens, CD; Biophysical Phenomena; Biophysics; Blood Platelets; Diffusion; Fibrinogen; Integrin beta3; Mathematics; Models, Biological; Platelet Activation; Platelet Aggregation; Platelet Glycoprotein GPIb-IX Complex; Platelet Membrane Glycoproteins; Receptors, Cell Surface | 1997 |
Platelet function and simultaneous thrombelastograms from whole blood and plasma.
Topics: Adenosine Diphosphate; Blood Platelets; Collagen; Factor X; Fibrin; Fibrinogen; Hemostasis; Humans; Platelet Aggregation; Platelet Count | 1998 |
In vitro hypothermia enhances platelet GPIIb-IIIa activation and P-selectin expression.
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Collagen; Dual Specificity Phosphatase 2; Female; Fibrinogen; Humans; Hypothermia, Induced; In Vitro Techniques; Male; Middle Aged; P-Selectin; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Phosphatase 2; Protein Tyrosine Phosphatases | 1998 |
Difference of (Ca2+)i movements in platelets stimulated by thrombin and TRAP: the involvement of alpha(IIb)beta3-mediated TXA2 synthesis.
Topics: Adenosine Diphosphate; Antibodies, Monoclonal; Apyrase; Aspirin; Blood Platelets; Calcium; Cyclooxygenase Inhibitors; Dipeptides; Fibrinogen; Humans; Ion Transport; Peptide Fragments; Phenylacetates; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIb-IX Complex; Platelet Glycoprotein GPIIb-IIIa Complex; Receptors, Thrombin; Signal Transduction; Sulfonamides; Thrombin; Thromboxane A2; Thromboxane B2; Tirofiban; Tyrosine | 1998 |
Fibrinolytic agents inhibit platelet adhesion onto collagen type I-coated surfaces at high blood flow conditions.
Topics: Adenosine Diphosphate; Collagen; Depression, Chemical; Fibrinogen; Fibrinolytic Agents; Hemorheology; Humans; Image Processing, Computer-Assisted; Microscopy, Video; Perfusion; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Ristocetin; Streptokinase; Urokinase-Type Plasminogen Activator; von Willebrand Factor | 1998 |
Fibrinogen as a factor of thrombosis: experimental study.
Topics: Adenosine Diphosphate; Animals; Disease Models, Animal; Fibrinogen; Humans; In Vitro Techniques; Male; Partial Thromboplastin Time; Platelet Aggregation; Prothrombin Time; Rats; Rats, Wistar; Risk Factors; Thromboembolism; Thrombophlebitis; Thrombosis | 1998 |
[Measurement of fibrinogen binding to platelets by flow cytometry: evaluation method for reflecting platelet activation].
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Female; Fibrinogen; Flow Cytometry; Humans; Male; Middle Aged; Platelet Activation; Reference Values; Reproducibility of Results | 1998 |
The contribution of the three hypothesized integrin-binding sites in fibrinogen to platelet-mediated clot retraction.
Topics: Adenosine Diphosphate; Afibrinogenemia; Animals; Binding Sites; Blood Platelets; CHO Cells; Clot Retraction; Cricetinae; Fibrinogen; Humans; Mutagenesis, Site-Directed; Oligopeptides; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Recombinant Fusion Proteins | 1998 |
Changes in platelet membrane glycoproteins before bone marrow transplantation and after engraftment--a pilot study.
Topics: Adenosine Diphosphate; Adult; Antibodies, Monoclonal; Bone Marrow Transplantation; Case-Control Studies; Female; Fibrinogen; Flow Cytometry; Fluorescent Dyes; Graft Survival; Humans; In Vitro Techniques; Male; Middle Aged; P-Selectin; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Membrane Glycoproteins; Quinacrine; Thrombosis; Transplantation Conditioning | 1998 |
Effects of a new platelet glycoprotein IIb/IIIa antagonist, SR121566, on platelet activation, platelet-leukocyte interaction and thrombin generation.
Topics: Adenosine Diphosphate; Adult; Aged; Benzylamines; Blood Platelets; Cell Aggregation; Female; Fibrinogen; Flow Cytometry; Humans; Iodine Radioisotopes; Leukocytes; Male; Middle Aged; Piperidines; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Thiazoles; Thrombin | 1998 |
Activation of alphaVbeta3 on vascular cells controls recognition of prothrombin.
Topics: Adenosine Diphosphate; Aorta; Calpain; Cytochalasin B; Endothelium, Vascular; Fibrinogen; Hemostasis; Homeostasis; Humans; Manganese; Oligopeptides; Protein Kinase C; Prothrombin; Receptors, Vitronectin; Signal Transduction; Tetradecanoylphorbol Acetate | 1998 |
Secreted ADP plays a central role in thrombin-induced phospholipase D activation in human platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adenosine Triphosphate; Apyrase; Blood Platelets; Blood Proteins; Enzyme Activation; Fibrinogen; Humans; Phospholipase D; Phosphoproteins; Phosphorylation; Protein Processing, Post-Translational; Purinergic Antagonists; Receptors, Thromboxane; Signal Transduction; Thionucleotides; Thrombin | 1998 |
Arterial thrombosis in heart failure.
Topics: Adenosine Diphosphate; Coronary Thrombosis; Epinephrine; Fibrinogen; Heart Failure; Hemorheology; Humans; Myocardial Infarction; Platelet Aggregation; Platelet Glycoprotein GPIb-IX Complex; Platelet Glycoprotein GPIIb-IIIa Complex; Pulmonary Edema; Vasoconstrictor Agents; von Willebrand Factor | 1998 |
Cancer procoagulant stimulates platelet adhesion.
Topics: Adenosine Diphosphate; Animals; Blood Coagulation Factors; Blood Platelets; Cell Adhesion; Collagen; Cysteine Endopeptidases; Fibrinogen; Neoplasm Proteins; Platelet Activation; Platelet Adhesiveness; Swine; Thrombin | 1999 |
Inhibition of 2-P-mercaptophenyl-1,4-naphthoquinone on human platelet function.
Topics: Adenosine Diphosphate; Blood Platelets; Calcium; Collagen; Fibrinogen; Humans; Inhibitory Concentration 50; Naphthoquinones; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Spectrometry, Fluorescence; Thromboxane B2 | 1999 |
Fibrinogen fragments and platelet dysfunction in uremia.
Topics: Adenosine Diphosphate; Antibodies, Monoclonal; Blood Platelets; Chymotrypsin; Fibrinogen; Humans; Male; Peptide Fragments; Platelet Activation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Reference Values; Uremia | 1999 |
Maintenance of GPIIb-IIIa avidity supporting "irreversible" fibrinogen binding is energy-dependent.
Topics: Adenosine Diphosphate; Androstadienes; Anti-Bacterial Agents; Antibodies, Monoclonal; Antimetabolites; Antimycin A; Benzoquinones; Blood Platelets; Deoxyglucose; Dimethyl Sulfoxide; Energy Metabolism; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Excipients; Fibrinogen; Humans; Lactams, Macrocyclic; Phosphorylation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Polylysine; Protein Binding; Protein-Tyrosine Kinases; Quinones; Rifabutin; Signal Transduction; Tyrosine; Wortmannin | 1999 |
Transforming growth factor beta1 enhances platelet aggregation through a non-transcriptional effect on the fibrinogen receptor.
Topics: Adenosine Diphosphate; Animals; Bleeding Time; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Collagen; Crosses, Genetic; Fatty Acids, Unsaturated; Fibrinogen; In Vitro Techniques; Megakaryocytes; Mice; Mice, Inbred Strains; Mice, Knockout; Mice, SCID; Platelet Aggregation; Platelet Count; Platelet Glycoprotein GPIIb-IIIa Complex; Signal Transduction; Thrombin; Thrombocytopenia; Transforming Growth Factor beta | 1999 |
Platelet GP IIIa Pl(A) polymorphisms display different sensitivities to agonists.
Topics: Abciximab; Adenosine Diphosphate; Adult; Amino Acid Substitution; Antibodies, Monoclonal; Aspirin; Blood Platelets; Cell Membrane; Dose-Response Relationship, Drug; Female; Fibrinogen; Gene Dosage; Genotype; Humans; Immunoglobulin Fab Fragments; Male; P-Selectin; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Polymorphism, Genetic; Reference Values | 2000 |
Platelet aggregation induced by ADP or epinephrine is enhanced in habitual smokers.
Topics: Adenosine Diphosphate; Adult; Aged; Body Mass Index; Epinephrine; Evaluation Studies as Topic; Fibrinogen; Humans; Male; Middle Aged; Platelet Aggregation; Smoking; Tobacco Use Disorder | 2000 |
Fused bicyclic Gly-Asp beta-turn mimics with potent affinity for GPIIb-IIIa. Exploration of the arginine isostere.
Topics: Acetates; Adenosine Diphosphate; Amidines; Animals; Arginine; Benzamidines; Biological Availability; Drug Evaluation; Enzyme-Linked Immunosorbent Assay; Fibrinogen; Humans; Inhibitory Concentration 50; Models, Molecular; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Prodrugs; Protein Binding; Protein Structure, Secondary; Rats; Stereoisomerism; Tetralones | 2000 |
c7E3 Fab inhibits low shear flow modulated platelet adhesion to endothelium and surface-absorbed fibrinogen by blocking platelet GP IIb/IIIa as well as endothelial vitronectin receptor--results from patients with acute myocardial infarction and healthy co
Topics: Abciximab; Adenosine Diphosphate; Adsorption; Adult; Antibodies, Monoclonal; Anticoagulants; Blood Flow Velocity; Blood Platelets; Cell Culture Techniques; Endothelium, Vascular; Fibrinogen; Glass; Hemorheology; Humans; Immunoglobulin Fab Fragments; Middle Aged; Myocardial Infarction; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Receptors, Vitronectin; Time Factors; Umbilical Veins; von Willebrand Factor | 2000 |
Analysis of prothrombotic effects of two human monoclonal IgG antiphospholipid antibodies of apparently similar specificity.
Topics: Adenosine Diphosphate; Animals; Antibodies, Antiphospholipid; Antibodies, Monoclonal; Antibody Specificity; Antiphospholipid Syndrome; Autoimmune Diseases; Biomarkers; Blood Coagulation Factors; Blood Platelets; Cattle; Cells, Cultured; Dose-Response Relationship, Immunologic; Endothelium, Vascular; Female; Fibrinogen; Humans; Immunoglobulin G; Intracranial Embolism; Lipopolysaccharides; Lupus Erythematosus, Systemic; Male; Middle Aged; Monocytes; Peptide Fragments; Platelet Activation; Recurrence; Thrombophilia; Thromboplastin | 2000 |
Chrysoptin is a potent glycoprotein IIb/IIIa fibrinogen receptor antagonist present in salivary gland extracts of the deerfly.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Animals; Base Sequence; Chromatography, High Pressure Liquid; Cloning, Molecular; Diptera; Electrophoresis, Polyacrylamide Gel; Fibrinogen; Insect Proteins; Molecular Sequence Data; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Proteins; Salivary Glands | 2000 |
Efficiency of platelet adhesion to fibrinogen depends on both cell activation and flow.
Topics: Adenosine Diphosphate; Blood Platelets; Fibrinogen; Humans; In Vitro Techniques; Kinetics; Oligopeptides; Platelet Activation; Platelet Adhesiveness; Platelet Glycoprotein GPIIb-IIIa Complex; Stress, Mechanical | 2000 |
Synergistic disaggregation of platelets by the products of endothelial cells or their analogs.
Topics: Adenosine Diphosphate; Blood Platelets; Dose-Response Relationship, Drug; Drug Synergism; Endothelium, Vascular; Epoprostenol; Fibrinogen; Flow Cytometry; Humans; Kinetics; Nitric Oxide; Nitroprusside; Platelet Aggregation; Platelet Aggregation Inhibitors; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator | 2000 |
Antiplatelet mechanisms of TA-993 and its metabolite MB3 in ADP-induced platelet aggregation.
Topics: Actins; Adenosine Diphosphate; Blood Platelets; Calcium; Cyclic AMP; Cyclic GMP; Diltiazem; Dose-Response Relationship, Drug; Fibrinogen; Fura-2; Humans; Male; Oligopeptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Binding | 2000 |
Comparative study of antithrombotic effect of a low molecular weight heparin and unfractionated heparin in an ex vivo model of deep arterial injury.
Topics: Adenosine Diphosphate; Animals; Arteries; Blood Coagulation Tests; Blood Flow Velocity; Collagen; Disease Models, Animal; Fibrin; Fibrinogen; Fibrinolytic Agents; Hematologic Tests; Heparin; Heparin, Low-Molecular-Weight; Perfusion; Platelet Aggregation; Platelet Function Tests; Swine; Thrombosis | 2000 |
Modification of protein moiety of human low density lipoprotein by hypochlorite generates strong platelet agonist.
Topics: Adenosine Diphosphate; Blood Platelets; Butylated Hydroxytoluene; Calcium; Collagen; Fibrinogen; Free Radical Scavengers; Humans; Hypochlorous Acid; Lipoproteins, LDL; Microscopy, Electron; Platelet Aggregation; Thiobarbituric Acid Reactive Substances; Thrombin | 2000 |
Effects of acetyl salicylic acid therapy on an experimental thrombosis induced by laser beam.
Topics: Adenosine Diphosphate; Animals; Aspirin; Bleeding Time; Disease Models, Animal; Fibrinogen; Lasers; Male; Partial Thromboplastin Time; Platelet Aggregation; Rats; Rats, Wistar; Thrombosis | 2000 |
High-density lipoproteins inhibit fibrinogen binding on adenosine diphosphate-activated monocytes.
Topics: Adenosine Diphosphate; Antibodies; CD18 Antigens; Cholesterol, HDL; Cholesterol, LDL; Dose-Response Relationship, Drug; Fibrinogen; Humans; Lipoproteins, HDL; Monocytes; Protein Binding | 2000 |
Active GPIIb-IIIa conformations that link ligand interaction with cytoskeletal reorganization.
Topics: Adenosine Diphosphate; Antibodies; Binding Sites; Blood Platelets; Clot Retraction; Cytoskeleton; Fibrinogen; Humans; Iodine Radioisotopes; Microscopy, Electron, Scanning; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Conformation; Talin | 2000 |
Influences of fixatives on flow cytometric measurements of platelet P-selectin expression and fibrinogen binding.
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Female; Fibrinogen; Fixatives; Flow Cytometry; Formaldehyde; Humans; Male; Middle Aged; P-Selectin; Platelet Activation; Polymers; Protein Binding | 2000 |
Antiplatelet action of R-99224, an active metabolite of a novel thienopyridine-type G(i)-linked P2T antagonist, CS-747.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cyclic AMP; Cyclopropanes; Fibrinogen; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; In Vitro Techniques; Male; Membrane Proteins; Piperazines; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Thionucleotides; Thiophenes | 2001 |
Adenosine diphosphate strongly potentiates the ability of the chemokines MDC, TARC, and SDF-1 to stimulate platelet function.
Topics: Adenosine Diphosphate; Apyrase; Blood Platelets; Calcium; Calcium Signaling; Chemokine CCL17; Chemokine CCL22; Chemokine CXCL12; Chemokines, CC; Chemokines, CXC; Collagen; Fibrinogen; Hemorheology; Humans; Indomethacin; Ion Transport; Microscopy, Electron, Scanning; P-Selectin; Platelet Activation; Platelet Adhesiveness; Thrombin | 2001 |
Purification, characterization, and cDNA sequence of halysetin, a disintegrin-like/cysteine-rich protein from the venom of Agkistrodon halys Pallas.
Topics: Adenosine Diphosphate; Agkistrodon; Amino Acid Sequence; Animals; Base Sequence; Chromatography, Agarose; Chromatography, Liquid; Collagen; Cysteine; Disintegrins; DNA, Complementary; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Esterases; Fibrin; Fibrinogen; Hydrogen-Ion Concentration; Isoelectric Focusing; Mass Spectrometry; Molecular Sequence Data; Phospholipases A; Phospholipases A2; Platelet Aggregation; Reverse Transcriptase Polymerase Chain Reaction; RNA; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Snake Venoms; Viper Venoms | 2000 |
Neonatal platelet activation in preeclampsia.
Topics: Adenosine Diphosphate; Antigens, CD; Biomarkers; Female; Fibrinogen; Flow Cytometry; HELLP Syndrome; Humans; Infant, Newborn; Male; Platelet Activation; Pre-Eclampsia; Pregnancy | 2001 |
The application of pig blood in the in vitro measurement of platelet adhesion.
Topics: Acid Phosphatase; Adenosine Diphosphate; Animals; Blood Proteins; Collagen; Fibrinogen; Humans; In Vitro Techniques; Platelet Adhesiveness; Platelet Count; Swine | 2001 |
RGD-containing peptides inhibit fibrinogen binding to platelet alpha(IIb)beta3 by inducing an allosteric change in the amino-terminal portion of alpha(IIb).
Topics: Adenosine Diphosphate; Allosteric Site; Animals; B-Lymphocytes; Blood Platelets; Carcinogens; Cell Adhesion; CHO Cells; Cricetinae; Dithiothreitol; DNA, Complementary; Dose-Response Relationship, Drug; Fibrinogen; Humans; Inhibitory Concentration 50; Ligands; Oligopeptides; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Protein Structure, Tertiary; Rats; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transfection | 2001 |
Lysophosphatidic acid-independent platelet activation by low-density lipoprotein.
Topics: Adenosine Diphosphate; Calcium; Cyclic AMP; Fibrinogen; Humans; Intracellular Signaling Peptides and Proteins; Lipoproteins, LDL; Lysophospholipids; Palmitates; Peptide Fragments; Phosphoserine; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Kinase C; Protein Serine-Threonine Kinases; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Lysophosphatidic Acid; rho-Associated Kinases; Signal Transduction | 2001 |
A comparison of the antiplatelet effect of S-nitrosoglutathione in whole blood and platelet-rich plasma.
Topics: Adenosine Diphosphate; Blood Platelets; Female; Fibrinogen; Flow Cytometry; Humans; Male; Nitric Oxide; P-Selectin; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Transfusion; S-Nitrosoglutathione | 2001 |
[Effect of Arg-Gly-Asp-Ser (RGDS) peptide on ADP-induced signal transduction of activated rat platelet].
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Fibrinogen; Male; Mitogen-Activated Protein Kinases; Oligopeptides; Phosphorylation; Platelet Activation; Platelet Aggregation; Protein Kinase C; Rats; Rats, Wistar; Signal Transduction | 1998 |
Effects of sodium citrate, low molecular weight heparin, and prostaglandin E1 on aggregation, fibrinogen binding, and enumeration of equine platelets.
Topics: Adenosine Diphosphate; Alprostadil; Animals; Anticoagulants; Blood Platelets; Calcium; Citrates; Fibrinogen; Fibrinolytic Agents; Flow Cytometry; Hematocrit; Heparin, Low-Molecular-Weight; Horses; Platelet Aggregation; Platelet Count; Sodium Citrate | 2001 |
Binding of recombinant apolipoprotein(a) to human platelets and effect on platelet aggregation.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Aminocaproic Acid; Apolipoproteins; Apoprotein(a); Arachidonic Acid; Binding, Competitive; Collagen; Fibrinogen; Humans; Lipoprotein(a); Molecular Sequence Data; Plasminogen; Platelet Aggregation; Protein Binding; Protein Isoforms; Proteins; Receptors, Thrombin; Recombinant Proteins; Thrombin; Tissue Plasminogen Activator | 2001 |
Effect of the Pl(A2) alloantigen on the function of beta(3)-integrins in platelets.
Topics: Adenosine Diphosphate; Adult; Aged; Antigens, CD; Antigens, Human Platelet; B-Lymphocytes; Blood Platelets; Coronary Thrombosis; Female; Fibrinogen; Heterozygote; Homozygote; Humans; Integrin beta3; Male; Middle Aged; Osteopontin; Platelet Adhesiveness; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Membrane Glycoproteins; Polymorphism, Genetic; Sialoglycoproteins; Transfection; Vitronectin | 2001 |
Alternative binding assay of GP IIb/IIIa antagonists with a nonradioactive labeling method of platelets.
Topics: Adenosine Diphosphate; Blood Platelets; Fibrinogen; Fluoresceins; Fluorescent Dyes; Humans; Inhibitory Concentration 50; Methods; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Spectrometry, Fluorescence | 2001 |
Genetic and environmental contributions to platelet aggregation: the Framingham heart study.
Topics: Adenosine Diphosphate; Adult; Age Factors; Aged; Aged, 80 and over; Binding Sites; Collagen; Deoxyribonuclease HindIII; DNA; Epinephrine; Female; Fibrinogen; Genotype; Humans; Male; Middle Aged; Multivariate Analysis; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Polymorphism, Genetic; Sex Factors; Time Factors | 2001 |
Platelet glycoprotein IIIa Pl(a) polymorphism, fibrinogen, and platelet aggregability: The Framingham Heart Study.
Topics: Adenosine Diphosphate; Alleles; Antigens, Human Platelet; Cardiovascular Diseases; Epinephrine; Epitopes; Female; Fibrinogen; Gene Frequency; Genetic Linkage; Genetic Predisposition to Disease; Genetic Testing; Genotype; Homozygote; Humans; Integrin beta3; Male; Middle Aged; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Polymorphism, Genetic; Risk Factors; Vasoconstrictor Agents; von Willebrand Factor | 2001 |
Normal tension glaucoma and primary open angle glaucoma associated with increased platelet aggregation.
Topics: Adenosine Diphosphate; Adult; Aged; alpha-2-Antiplasmin; Collagen; Escherichia coli Proteins; Female; Fibrinogen; Fibrinolysin; Fibrinolysis; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Membrane Transport Proteins; Middle Aged; Partial Thromboplastin Time; Platelet Aggregation; Prothrombin Time | 2001 |
RAFTK/Pyk2 involvement in platelet activation is mediated by phosphoinositide 3-kinase.
Topics: Adenosine Diphosphate; Chromones; Collagen; Enzyme Inhibitors; Fibrinogen; Focal Adhesion Kinase 2; Humans; Intracellular Signaling Peptides and Proteins; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoric Monoester Hydrolases; Phosphorylation; Platelet Activation; Precipitin Tests; Protein Phosphatase 2; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Signal Transduction; Thrombin; Vanadates | 2001 |
Resistance to thromboembolism in PI3Kgamma-deficient mice.
Topics: Adenosine Diphosphate; Animals; Bleeding Time; Blood Platelets; Class Ib Phosphatidylinositol 3-Kinase; Fibrinogen; GTP-Binding Proteins; Isoenzymes; Mice; Mice, Knockout; Phosphatidylinositol 3-Kinases; Phosphorylation; Platelet Aggregation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, Cell Surface; Thromboembolism | 2001 |
Differential inhibition of adenosine diphosphate- versus thrombin receptor-activating peptide-stimulated platelet fibrinogen binding by abciximab due to different glycoprotein IIb/IIIa activation kinetics.
Topics: Abciximab; Adenosine Diphosphate; Antibodies, Monoclonal; Biotinylation; Depression, Chemical; Dose-Response Relationship, Drug; Eptifibatide; Fibrinogen; Humans; Immunoglobulin Fab Fragments; Kinetics; Peptides; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Proteins; Receptors, Thrombin; Tirofiban; Tyrosine | 2001 |
Platelet activation by sustained exposure to low-dose plasmin.
Topics: Adenosine Diphosphate; Alprostadil; Blood Platelets; Clot Retraction; Edetic Acid; Enzyme Inhibitors; Fibrinogen; Fibrinolysin; Humans; Phosphoinositide-3 Kinase Inhibitors; Platelet Activation; Platelet Factor 4; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Kinase C; Serotonin | 2001 |
Role of phosphoinositide 3-kinase in adhesion of platelets to fibrinogen stimulated by cancer procoagulant.
Topics: Adenosine Diphosphate; Androstadienes; Animals; Cysteine Endopeptidases; Dose-Response Relationship, Drug; Fibrinogen; Neoplasm Proteins; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Platelet Activation; Platelet Adhesiveness; Swine; Thrombin; Wortmannin | 2001 |
Platelet aggregation is not initiated by platelet shape change.
Topics: Adenosine Diphosphate; Antineoplastic Agents, Phytogenic; Blood Platelets; Cell Size; Cytochalasin D; Fibrinogen; Hemostatics; Humans; Microspheres; Nucleic Acid Synthesis Inhibitors; Peptide Fragments; Platelet Aggregation; Temperature; Thrombin; Vincristine | 2001 |
A Val193Met mutation in GPIIIa results in a GPIIb/IIIa receptor with a constitutively high affinity for a small ligand.
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Cell Line; Female; Fibrinogen; Humans; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Point Mutation; Protein Binding; Radioligand Assay; Reverse Transcriptase Polymerase Chain Reaction; Structure-Activity Relationship; T-Lymphocytes; Thrombasthenia; Transfection | 2001 |
Adenosine diphosphate (ADP)-induced thromboxane A(2) generation in human platelets requires coordinated signaling through integrin alpha(IIb)beta(3) and ADP receptors.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Blood Platelets; Dipeptides; Enzyme Activation; Enzyme Inhibitors; Fibrinogen; Humans; Membrane Proteins; Phospholipases A; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Signal Transduction; Thromboxane A2 | 2002 |
The ability of poloxamers to inhibit platelet aggregation depends on their physicochemical properties.
Topics: Adenosine Diphosphate; Adsorption; Antibodies, Monoclonal; Calorimetry, Differential Scanning; Drug Evaluation, Preclinical; Fibrinogen; Humans; Kinetics; Micelles; Microspheres; Molecular Weight; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Poloxamer; Protein Binding; Solubility; Structure-Activity Relationship; Surface Properties; Viscosity | 2001 |
Pharmacological properties of YM-57029, a novel platelet glycoprotein IIb/IIIa antagonist.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Benzamidines; Biotinylation; Bleeding Time; Blood Platelets; Collagen; Cricetinae; Dogs; Dose-Response Relationship, Drug; Fibrinogen; Fibrinolytic Agents; Guinea Pigs; Haplorhini; Humans; Mice; Microspheres; Oligopeptides; Piperazines; Piperidines; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Rabbits; Rats; Stress, Mechanical | 2002 |
GpIIb/IIIa is the main receptor for initial platelet adhesion to glass and titanium surfaces in contact with whole blood.
Topics: Adenosine Diphosphate; Animals; Antibodies, Monoclonal; Blood; Blood Platelets; Chemical Phenomena; Chemistry, Physical; Collagen; Fibrinogen; Fluorescent Antibody Technique; Glass; Humans; Immunoblotting; Mice; Platelet Adhesiveness; Platelet Glycoprotein GPIIb-IIIa Complex; Surface Properties; Titanium | 2002 |
An additional mechanism of action of abciximab: dispersal of newly formed platelet aggregates.
Topics: Abciximab; Adenosine Diphosphate; Antibodies, Monoclonal; Aspirin; Blood Platelets; Dose-Response Relationship, Drug; Drug Synergism; Fibrinogen; Humans; Immunoglobulin Fab Fragments; Kinetics; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding | 2002 |
Interactions between Eph kinases and ephrins provide a mechanism to support platelet aggregation once cell-to-cell contact has occurred.
Topics: Adenosine Diphosphate; Blood Platelets; Cell Adhesion; Collagen; Ephrin-B1; Fetal Proteins; Fibrinogen; Hemostasis; Humans; In Vitro Techniques; Leukocyte L1 Antigen Complex; Membrane Glycoproteins; Membrane Proteins; Models, Biological; Neural Cell Adhesion Molecules; Platelet Aggregation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; rap GTP-Binding Proteins; Receptor Protein-Tyrosine Kinases; Receptor, EphA4; Receptors, Eph Family; Recombinant Fusion Proteins; Signal Transduction; src-Family Kinases; Thrombin | 2002 |
Biphasic effects of hemodialysis on platelet reactivity in patients with end-stage renal disease: a potential contributor to cardiovascular risk.
Topics: Adenosine Diphosphate; Coronary Artery Disease; Female; Fibrinogen; Flow Cytometry; Humans; Kidney Failure, Chronic; Male; Membranes, Artificial; Microscopy, Confocal; Middle Aged; Myocardial Infarction; P-Selectin; Platelet Activation; Platelet Aggregation; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Renal Dialysis; Risk Factors | 2002 |
Studies of fibrinogen binding to porcine platelets by flow cytometry: a method for studies of porcine platelet activation.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Fibrinogen; Flow Cytometry; Platelet Activation; Platelet Adhesiveness; Platelet Function Tests; Protein Binding; Ristocetin; Swine; Thrombin | 2002 |
Insulin, but not proinsulin C-peptide, enhances platelet fibrinogen binding in vitro in Type 1 diabetes mellitus patients and healthy subjects.
Topics: Adenosine Diphosphate; Adult; Blood Platelets; C-Peptide; Diabetes Mellitus, Type 1; Fibrinogen; Humans; Insulin; Male; Middle Aged; P-Selectin; Peptides; Platelet Activation; Protein Binding; Receptors, Fibrinogen; Stimulation, Chemical | 2002 |
Costimulation of Gi- and G12/G13-mediated signaling pathways induces integrin alpha IIbbeta 3 activation in platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood Platelets; Collagen; DNA-Binding Proteins; Dose-Response Relationship, Drug; Fibrinogen; GTP-Binding Protein alpha Subunits, G12-G13; GTP-Binding Protein alpha Subunits, Gi-Go; Heterotrimeric GTP-Binding Proteins; Intracellular Signaling Peptides and Proteins; Mice; Mice, Transgenic; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Protein Serine-Threonine Kinases; rho-Associated Kinases; Signal Transduction; Thrombin; Thromboxane A2 | 2002 |
Interactions of platelets with Synthocytes, a novel platelet substitute.
Topics: Adenosine Diphosphate; Adolescent; Adult; Albumins; Blood Platelets; Blood Substitutes; Capsules; Drug Interactions; Female; Fibrinogen; Flow Cytometry; Hemostasis; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Serotonin; Thrombocytopenia | 2002 |
A Ser752-->Pro substitution in the cytoplasmic domain of beta3 in a Glanzmann thrombasthenia variant fails to prevent interactions between the alphaIIbbeta3 integrin and the platelet granule pool of fibrinogen.
Topics: Adenosine Diphosphate; Aged; Blood Platelets; Case-Control Studies; Fibrinogen; Humans; Integrin beta3; Male; Microscopy, Immunoelectron; Mutation; Platelet Activation; Platelet Membrane Glycoprotein IIb; Protein Binding; Stimulation, Chemical; Thrombasthenia | 2002 |
No evidence for an influence of the human platelet antigen-1 polymorphism on the antiplatelet effects of glycoprotein IIb/IIIa inhibitors.
Topics: Abciximab; Adenosine Diphosphate; Antibodies, Monoclonal; Antigens, Human Platelet; Blood Platelets; Fibrinogen; Genotype; Humans; Immunoglobulin Fab Fragments; Integrin beta3; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Polymorphism, Genetic; Tirofiban; Tyrosine | 2002 |
Immunolocalization of P2Y1 and TPalpha receptors in platelets showed a major pool associated with the membranes of alpha -granules and the open canalicular system.
Topics: Adenosine Diphosphate; Adult; Antibodies, Monoclonal; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Cytoplasmic Granules; Fatty Acids, Unsaturated; Fibrinogen; Flow Cytometry; Humans; Immunohistochemistry; Intracellular Membranes; Megakaryocytes; Microscopy, Electron; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Thromboxane; Thionucleotides | 2003 |
Blockade of platelet GPIIB-IIIA (Integrin alphaII(b)beta(3)) in flowing human blood leads to passivation of prothrombotic surfaces.
Topics: Adenosine Diphosphate; Collagen; Fibrinogen; Hemorheology; Humans; Integrin alpha2beta1; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Thrombosis | 2002 |
Functional phenotype of phosphoinositide 3-kinase p85alpha-null platelets characterized by an impaired response to GP VI stimulation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Blood Platelets; Carrier Proteins; Collagen; Crotalid Venoms; Fibrinogen; Mice; Mice, Inbred C57BL; Mice, Knockout; P-Selectin; Peptides; Phenotype; Phosphatidylinositol 3-Kinases; Phosphorylation; Platelet Aggregation; Platelet Membrane Glycoproteins; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate; Thrombin | 2003 |
A whole blood flow cytometric determination of platelet activation by unfractionated and low molecular weight heparin in vitro.
Topics: Adenosine Diphosphate; Adult; Blood; Fibrinogen; Flow Cytometry; Heparin; Heparin, Low-Molecular-Weight; Humans; P-Selectin; Platelet Activation | 2002 |
Association of CIB with GPIIb/IIIa during outside-in signaling is required for platelet spreading on fibrinogen.
Topics: Adenosine Diphosphate; Adult; Aged; Blood Platelets; Calcium-Binding Proteins; Carrier Proteins; Cell Movement; Cytoskeleton; Fibrinogen; Fluorescent Antibody Technique; Humans; Middle Aged; Platelet Adhesiveness; Platelet Glycoprotein GPIIb-IIIa Complex; Precipitin Tests; Pseudopodia; Recombinant Proteins; Signal Transduction | 2003 |
The minimum concentration of fibrinogen needed for platelet aggregation using ADP.
Topics: Adenosine Diphosphate; Adolescent; Adult; Female; Fibrinogen; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Function Tests | 2002 |
Effect of low doses of ethanol on platelet function in long-life abstainers and moderate-wine drinkers.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adult; Alcohol Drinking; Blood Platelets; Central Nervous System Depressants; Cholesterol; Collagen; Dose-Response Relationship, Drug; Ethanol; Female; Fibrinogen; Humans; Lipoproteins, HDL; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombin; Thromboxane B2; Triglycerides; Wine | 2003 |
Exposure of fibrinogen-adherent platelets to plasma proteins: a new method for studying protein interactions with platelets.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Blood Platelets; Blood Proteins; Fibrinogen; Fluorescent Antibody Technique; Humans; Immunohistochemistry; Platelet Factor 4 | 2003 |
Mapping the binding domains of the alpha(IIb) subunit. A study performed on the activated form of the platelet integrin alpha(IIb)beta(3).
Topics: Adenosine Diphosphate; Amino Acid Motifs; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Binding Sites; Blood Platelets; Dose-Response Relationship, Drug; Dual Specificity Phosphatase 2; Fibrinogen; Fluorescein; Humans; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Peptides; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Protein Phosphatase 2; Protein Structure, Tertiary; Protein Subunits; Protein Tyrosine Phosphatases | 2003 |
EFFECTS OF INORGANIC IONS AND OF PLASMA PROTEINS ON THE AGGREGATION OF BLOOD PLATELETS BY ADENOSINE DIPHOSPHATE.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Alpha-Globulins; Aluminum; Animals; Biomedical Research; Blood Platelets; Blood Proteins; Calcium; Factor VIII; Fibrinogen; gamma-Globulins; Heparin; Humans; Ions; Magnesium; Pharmacology; Physiology; Potassium; Research; Serum Globulins; Swine; Temperature | 1964 |
FIBRINOGEN AND ADENOSINE DIPHOSPHATE-INDUCED AGGREGATION OF PLATELETS.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Animals; Blood; Blood Platelets; Calcium; Colorimetry; Extracellular Space; Fibrinogen; Rabbits; Research; Thrombin | 1964 |
EFFECT OF FIBRINOGEN ON THE AGGREGATION OF PLATELETS BY ADENOSINE DIPHOSPHATE.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Blood Platelets; Coagulants; Factor VIII; Fibrinogen; Hemostatics; Humans | 1964 |
PLASMA THROMBOCYTE-AGGLUTINATING ACTIVITY AND FIBRINOGEN. SYNERGISM WITH ADENOSINE DIPHOSPHATE.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Animals; Blood Platelets; Dogs; Factor V; Factor VIII; Fibrinogen; Hemagglutination; Swine | 1965 |
Identification of low-density platelet populations with increased reactivity and elevated alpha-granule content.
Topics: Adenosine Diphosphate; Blood Platelets; Cell Fractionation; Centrifugation, Density Gradient; Cytoplasmic Granules; Fibrinogen; Humans; P-Selectin | 2003 |
Effect of synthetic peptides corresponding to residues 313-332 of the alphaIIb subunit on platelet activation and fibrinogen binding to alphaIIbbeta3.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Sequence; Antibodies, Monoclonal; Collagen; Dose-Response Relationship, Drug; Dual Specificity Phosphatase 2; Fibrinogen; Flow Cytometry; Humans; Inhibitory Concentration 50; Molecular Sequence Data; Oligopeptides; Peptide Fragments; Platelet Activation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Phosphatase 2; Protein Tyrosine Phosphatases; Thrombin | 2004 |
LDL oxidized by hypochlorous acid causes irreversible platelet aggregation when combined with low levels of ADP, thrombin, epinephrine, or macrophage-derived chemokine (CCL22).
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Blood Platelets; Calcium; Cell Size; Chemokine CCL22; Chemokines, CC; Cholesterol, LDL; Enzyme Inhibitors; Epinephrine; Fibrinogen; Hemostatics; Humans; Hypochlorous Acid; Imidazoles; Indoles; Lipoproteins, LDL; Maleimides; Mitogen-Activated Protein Kinases; Oxidation-Reduction; P-Selectin; p38 Mitogen-Activated Protein Kinases; Platelet Aggregation; Protein Kinase C; Pyridines; Secretory Vesicles; Serotonin; Sympathomimetics; Thrombin | 2004 |
Impaired platelet responses to thrombin and collagen in AKT-1-deficient mice.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Bleeding Time; Blood Platelets; Calcium; Collagen; Fibrinogen; Integrin beta3; Mice; Mice, Knockout; P-Selectin; Phorbol 12,13-Dibutyrate; Phosphorylation; Platelet Adhesiveness; Platelet Aggregation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Thrombin | 2004 |
Impaired platelet activation in familial high density lipoprotein deficiency (Tangier disease).
Topics: Adenosine Diphosphate; Aged; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Blood Platelets; Cell Adhesion Molecules; Collagen; Cytoplasmic Granules; Fibrinogen; Humans; Hydrogen-Ion Concentration; Lysosomal Membrane Proteins; Lysosomes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Electron; Middle Aged; Phosphatidylserines; Platelet Activation; Platelet Membrane Glycoproteins; Tangier Disease; Tetraspanin 30; Thrombin | 2004 |
Altered platelet reactivity in peripheral vascular disease complicated with elevated plasma homocysteine levels.
Topics: Adenosine Diphosphate; Aged; Blood Platelets; Fibrinogen; Flow Cytometry; Homocysteine; Humans; Intermittent Claudication; Middle Aged; Nitric Oxide; Nitric Oxide Donors; P-Selectin; Peripheral Vascular Diseases; Platelet Activation; S-Nitrosoglutathione; Sulfhydryl Compounds | 2004 |
Soluble fibrin is the main mediator of Staphylococcus aureus adhesion to platelets.
Topics: Adenosine Diphosphate; Ancrod; Animals; Bacterial Adhesion; Blood Platelet Disorders; Blood Platelets; Coagulase; Cytoplasmic Granules; Fibrin; Fibrinogen; Hirudins; Humans; Mice; Mice, Knockout; Oligopeptides; Platelet Activation; Protein Binding; Staphylococcus aureus; Thrombin; Thrombospondin 1 | 2004 |
Mechanism of activation of ADP-induced platelet aggregation under the influence of oxidatively modified fibrinogen.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Diphosphate; Aspirin; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Estrenes; Fibrinogen; Genistein; Humans; In Vitro Techniques; Oxidation-Reduction; Platelet Aggregation; Protein Kinase C; Protein-Tyrosine Kinases; Pyrrolidinones; Type C Phospholipases; Ultraviolet Rays | 2004 |
Role of fibrinogen- and platelet-mediated hemostasis in mouse embryogenesis and reproduction.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Collagen; Crosses, Genetic; DNA-Binding Proteins; Embryo, Mammalian; Erythroid-Specific DNA-Binding Factors; Fibrinogen; Genotype; GTP-Binding Protein alpha Subunits, Gq-G11; Hemostasis; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-E2 Transcription Factor; NF-E2 Transcription Factor, p45 Subunit; Placenta; Polymerase Chain Reaction; Reproduction; Time Factors; Transcription Factors; Transgenes; Yolk Sac | 2004 |
Effects of warm-up on exercise capacity, platelet activation and platelet-leucocyte aggregation in patients with claudication.
Topics: Adenosine Diphosphate; Aged; Case-Control Studies; Cohort Studies; Cross-Over Studies; Exercise; Exercise Test; Female; Fibrinogen; Flow Cytometry; Humans; Intermittent Claudication; Leukocytes; Male; Middle Aged; Neutrophil Activation; Neutrophils; P-Selectin; Platelet Activation; Platelet Aggregation | 2005 |
Importance of temporal flow gradients and integrin alphaIIbbeta3 mechanotransduction for shear activation of platelets.
Topics: Adenosine Diphosphate; Blood Platelets; Calcium; Cytosol; Fibrinogen; Humans; Integrins; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation; Platelet Glycoprotein GPIb-IX Complex; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Membrane Glycoprotein IIb; Signal Transduction; Time Factors; von Willebrand Factor | 2005 |
Thrombopoietin complements G(i)- but not G(q)-dependent pathways for integrin {alpha}(IIb){beta}(3) activation and platelet aggregation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Androstadienes; Antibodies, Monoclonal; Blood Platelets; Blood Proteins; Calcium; Chromones; Cyclooxygenase Inhibitors; Cytosol; Enzyme Activation; Enzyme Inhibitors; Fibrinogen; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; Humans; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoproteins; Platelet Activation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Proto-Oncogene Proteins; rap GTP-Binding Proteins; Receptors, Cytokine; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Thrombopoietin; Thrombopoietin; Thromboxane A2; Thromboxanes; Time Factors; Type C Phospholipases; Wortmannin | 2005 |
A novel anti-platelet monoclonal antibody (3C7) specific for the complex of integrin alpha IIb beta3 inhibits platelet aggregation and adhesion.
Topics: Adenosine Diphosphate; Animals; Antibodies, Monoclonal; Antibody Specificity; Blood Platelets; CHO Cells; Cricetinae; Epitopes; Fibrinogen; Hemostatics; Mice; Mice, Inbred BALB C; Platelet Adhesiveness; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombin | 2005 |
Characterisation of species differences in the platelet ADP and thrombin response.
Topics: Adenosine Diphosphate; Animals; Apyrase; Blood Platelets; Dogs; Dose-Response Relationship, Drug; Female; Fibrinogen; Flow Cytometry; Guinea Pigs; Humans; Male; Mice; Mice, Inbred C57BL; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Reference Values; Species Specificity; Thrombin | 2006 |
Influence of extracellular calcium on single platelet activation as measured by whole blood flow cytometry.
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Calcium; Female; Fibrinogen; Flow Cytometry; Humans; Male; Middle Aged; P-Selectin; Platelet Activation; Platelet Aggregation; Thromboxane A2 | 2005 |
Variation in the ability of glycoprotein IIb-IIIa antagonists to exert and maintain their inhibitory effects on the binding of fibrinogen.
Topics: Adenosine Diphosphate; Aged; Binding, Competitive; Blood Platelets; Clopidogrel; Coronary Artery Disease; Data Interpretation, Statistical; Eptifibatide; Fibrinogen; Flow Cytometry; Fluorescein-5-isothiocyanate; Humans; Iodine Radioisotopes; Male; Peptide Fragments; Peptides; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Receptors, Thrombin; Ticlopidine; Tirofiban; Tyrosine | 2005 |
ClfA(221-550), a fibrinogen-binding segment of Staphylococcus aureus clumping factor A, disrupts fibrinogen function.
Topics: Adenosine Diphosphate; Blood Coagulation; Blood Platelets; Catalysis; Chromatography, High Pressure Liquid; Cloning, Molecular; Coagulase; Cross-Linking Reagents; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Factor XIIIa; Fibrin; Fibrinogen; Fibrinolytic Agents; Flow Cytometry; Fluorescein-5-isothiocyanate; Humans; Peptide Fragments; Platelet Adhesiveness; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Recombinant Proteins; Staphylococcus aureus; Thrombin; Time Factors | 2005 |
Regulation of platelet guanylyl cyclase by collagen: evidence that Glycoprotein VI mediates platelet nitric oxide synthesis in response to collagen.
Topics: Adenosine Diphosphate; Blood Platelets; Calcium; Citrulline; Collagen; Cyclic GMP; Dose-Response Relationship, Drug; Fibrinogen; Guanylate Cyclase; Humans; Immunoblotting; Immunoprecipitation; Nitric Oxide; Nitric Oxide Synthase; Peptides; Phosphatidylinositol 3-Kinases; Platelet Activation; Platelet Membrane Glycoproteins; Protein Kinase C; Signal Transduction; src-Family Kinases; Thromboxane A2 | 2005 |
Inhibition and reversal of platelet aggregation by alphaIIbbeta3 antagonists depends on the anticoagulant and flow conditions: differential effects of Abciximab and Lamifiban.
Topics: Abciximab; Acetates; Adenosine Diphosphate; Antibodies, Monoclonal; Anticoagulants; Blood Platelets; Blood Specimen Collection; Fibrinogen; Hemorheology; Humans; Immunoglobulin Fab Fragments; P-Selectin; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Tyrosine | 2005 |
Anti-thrombic activity of Korean herbal medicine, Dae-Jo-Whan and its herbs.
Topics: Adenosine Diphosphate; Animals; Cholesterol, Dietary; Collagen; Disseminated Intravascular Coagulation; Endotoxins; Fibrin; Fibrinogen; Fibrinolysin; Fibrinolytic Agents; Heparin; Hyperlipidemias; Korea; Male; Plant Extracts; Plasminogen; Platelet Aggregation; Rats; Rats, Wistar; Thrombin | 2005 |
PI3-kinase is essential for ADP-stimulated integrin alpha(IIb)beta3-mediated platelet calcium oscillation, implications for P2Y receptor pathways in integrin alpha(IIb)beta3-initiated signaling cross-talks.
Topics: Actins; Adenosine Diphosphate; Adenosine Triphosphate; Androstadienes; Blood Platelets; Calcium; Cell Adhesion; Class I Phosphatidylinositol 3-Kinases; Cytoskeleton; Enzyme-Linked Immunosorbent Assay; Escherichia coli; Fibrinogen; Humans; Integrins; Membrane Proteins; Microscopy, Confocal; Microscopy, Video; Models, Statistical; Oscillometry; P-Selectin; Peptides; Phosphatidylinositol 3-Kinases; Plasmids; Platelet Glycoprotein GPIIb-IIIa Complex; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Recombinant Fusion Proteins; Recombinant Proteins; Signal Transduction; Time Factors; Wortmannin | 2005 |
Effects of platelet binding on whole blood flow cytometry assays of monocyte and neutrophil procoagulant activity.
Topics: Adenosine Diphosphate; Adult; Blood Coagulation; Blood Platelets; CD11b Antigen; Cell Aggregation; Cell Communication; Cell Separation; Collagen; Factor Xa; Female; Fibrinogen; Flow Cytometry; Humans; Macrophage-1 Antigen; Male; Middle Aged; Monocytes; Neutrophils; Platelet Activation; Platelet Glycoprotein GPIb-IX Complex; Thromboplastin | 2005 |
Platelet aggregation in portal hypertension and its modification by ultra-low doses of aspirin.
Topics: Adenosine Diphosphate; Animals; Aspirin; Fibrinogen; Hemorrhage; Humans; Hypertension, Portal; Injections, Subcutaneous; Male; Partial Thromboplastin Time; Platelet Aggregation; Platelet Aggregation Inhibitors; Prothrombin Time; Rats; Rats, Wistar | 2005 |
Biological properties of a specific Galpha q/11 inhibitor, YM-254890, on platelet functions and thrombus formation under high-shear stress.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Calcium; Cell Shape; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Femoral Artery; Fibrinogen; Fibrinolytic Agents; GTP-Binding Protein alpha Subunits, Gq-G11; Ligation; Macaca fascicularis; P-Selectin; Peptides, Cyclic; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptors, Thrombin; Regional Blood Flow; Stress, Mechanical; Thrombosis | 2006 |
High glucose levels enhance platelet activation: involvement of multiple mechanisms.
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Female; Fibrinogen; Flow Cytometry; Galactose; Glucose; Humans; Hyperglycemia; Male; Middle Aged; Osmolar Concentration; P-Selectin; Peptide Fragments; Platelet Activation; Platelet Aggregation; Protein Kinase C; Sucrose; Superoxides | 2006 |
PAR4, but not PAR1, signals human platelet aggregation via Ca2+ mobilization and synergistic P2Y12 receptor activation.
Topics: Adenosine Diphosphate; Blood Platelets; Calcium; Calcium Signaling; Chelating Agents; Egtazic Acid; Fibrinogen; Humans; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Purinergic P2 Receptor Antagonists; Receptor, PAR-1; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Receptors, Thrombin; Thrombin | 2006 |
The adhesion of blood platelets on fibrinogen surface: comparison of two biochemical microplate assays.
Topics: Acid Phosphatase; Adenosine Diphosphate; Biocompatible Materials; Fibrin; Fibrinogen; Humans; L-Lactate Dehydrogenase; Materials Testing; Platelet Adhesiveness; Thrombin | 2006 |
Protease-activating receptor-4 induces full platelet spreading on a fibrinogen matrix: involvement of ERK2 and p38 and Ca2+ mobilization.
Topics: Actins; Adenosine Diphosphate; Blood Platelets; Calcium; Calcium Signaling; Cytoskeleton; Extracellular Matrix; Fibrinogen; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Myosin Light Chains; p38 Mitogen-Activated Protein Kinases; Peptides; Phosphorylation; Platelet Adhesiveness; Platelet Glycoprotein GPIIb-IIIa Complex; Receptor, PAR-1; Receptors, Thrombin; Thrombin; Thrombosis | 2007 |
Inhibition of ADP-induced platelet adhesion to immobilised fibrinogen by nitric oxide: evidence for cGMP-independent mechanisms.
Topics: Adenosine Diphosphate; Blood Platelets; Calcium; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Fibrinogen; Humans; Nitric Oxide; Phosphatidylinositol 3-Kinases; Phosphorylation; Platelet Adhesiveness; Platelet Glycoprotein GPIIb-IIIa Complex; Signal Transduction; Tyrosine | 2007 |
A major role for Scar/WAVE-1 downstream of GPVI in platelets.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Carrier Proteins; Collagen; Cytoskeleton; Fibrinogen; Hemorheology; Humans; In Vitro Techniques; Laminin; Mice; Mice, Knockout; P-Selectin; Peptides; Platelet Activation; Platelet Membrane Glycoproteins; Pseudopodia; Signal Transduction; Stress, Mechanical; Thrombin; Wiskott-Aldrich Syndrome Protein Family | 2007 |
Modulation of ADP-induced platelet activation by aspirin and pravastatin: role of lectin-like oxidized low-density lipoprotein receptor-1, nitric oxide, oxidative stress, and inside-out integrin signaling.
Topics: Adenosine Diphosphate; Aspirin; Blood Platelets; Drug Therapy, Combination; Fibrinogen; Humans; Integrin alpha2beta1; Nitric Oxide; Oxidative Stress; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Pravastatin; Scavenger Receptors, Class E; Signal Transduction | 2007 |
Parnaparin, a low-molecular-weight heparin, prevents P-selectin-dependent formation of platelet-leukocyte aggregates in human whole blood.
Topics: Adenosine Diphosphate; Anti-Inflammatory Agents; Blood Platelets; CD11b Antigen; CD40 Antigens; Cell Adhesion; Collagen; Dose-Response Relationship, Drug; Enoxaparin; Fibrinogen; Heparin, Low-Molecular-Weight; Humans; In Vitro Techniques; Leukocytes; P-Selectin; Peptide Fragments; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Stress, Mechanical; Thrombin; Thromboplastin | 2007 |
Do ADP-activated platelets in vitro aggregate as discocytes?
Topics: Adenosine Diphosphate; Blood Platelets; Cell Shape; Cells, Cultured; Fibrinogen; Humans; Microscopy, Electron; Platelet Activation; Platelet Aggregation | 2007 |
Platelet activation, myocardial ischemic events and postoperative non-response to aspirin in patients undergoing major vascular surgery.
Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Female; Fibrinogen; Genetic Predisposition to Disease; Humans; Male; Middle Aged; Myocardial Ischemia; P-Selectin; Platelet Activation; Vascular Surgical Procedures | 2007 |
Protease-activated receptor-induced Akt activation--regulation and possible function.
Topics: Adenosine Diphosphate; Blood Platelets; Blotting, Western; Enzyme Activation; Fibrinogen; Flow Cytometry; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; In Vitro Techniques; Oligopeptides; P-Selectin; Phosphatidylinositol 3-Kinases; Phosphorylation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Receptor Cross-Talk; Receptor, PAR-1; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Receptors, Thrombin; Signal Transduction; Thrombin; Time Factors; Type C Phospholipases | 2007 |
The role of Akt in the signaling pathway of the glycoprotein Ib-IX induced platelet activation.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Fibrinogen; Humans; Integrins; Intracellular Signaling Peptides and Proteins; Mice; Mice, Knockout; Phosphatidylinositol 3-Kinases; Phosphatidylinositols; Platelet Adhesiveness; Platelet Glycoprotein GPIb-IX Complex; Platelet Membrane Glycoproteins; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Syk Kinase; Thromboxane A2; von Willebrand Factor | 2008 |
Freeze-dried platelets promote hepatocyte proliferation in mice.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Blood Platelets; Cell Proliferation; Coculture Techniques; Fibrinogen; Freeze Drying; Hepatocyte Growth Factor; Hepatocytes; Insulin-Like Growth Factor I; Male; Mice; Mice, Inbred BALB C; Microscopy, Electron, Transmission; Platelet-Derived Growth Factor | 2007 |
The effect of tirofiban on fibrinogen/agonist-induced platelet shape change and aggregation.
Topics: Adenosine Diphosphate; Blood Platelets; Cell Shape; Fibrinogen; Fibrinolytic Agents; Humans; In Vitro Techniques; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptors, Fibrinogen; Serotonin; Tirofiban; Tyrosine | 2008 |
[Suppressive effect in vitro of resveratrol on ADP induced human platelet aggregation and its active mechanism].
Topics: Adenosine Diphosphate; Blood Platelets; Dose-Response Relationship, Drug; Drug Synergism; Estrenes; Fibrinogen; Humans; Phospholipase C beta; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrrolidinones; Resveratrol; Stilbenes | 2008 |
Species differences in small molecule binding to alpha IIb beta 3 are the result of sequence differences in 2 loops of the alpha IIb beta propeller.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Animals; Cell Line; Conserved Sequence; Cricetinae; Eptifibatide; Fibrinogen; Humans; Mice; Molecular Sequence Data; Peptides; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Rats; Recombinant Proteins; Sequence Alignment; Tirofiban; Tyrosine | 2009 |
Adenosine diphosphate-induced platelet aggregation correlates with platelet activation identified with the use of flow cytometry.
Topics: Adenosine Diphosphate; Aged; Aged, 80 and over; Atherosclerosis; Female; Fibrinogen; Flow Cytometry; Humans; Male; Middle Aged; Nephelometry and Turbidimetry; Platelet Activation; Platelet Aggregation | 2008 |
Development of fibrinogen gamma-chain peptide-coated, adenosine diphosphate-encapsulated liposomes as a synthetic platelet substitute.
Topics: Adenosine Diphosphate; Animals; Blood Coagulation; Blood Platelets; Capsules; Coated Materials, Biocompatible; Drug Delivery Systems; Fibrinogen; Hemorrhage; Hemostasis; Liposomes; Nanoparticles; Rabbits; Rats; Thrombocytopenia | 2009 |
Purification and characterization of a new platelet aggregation inhibitor with dissociative effect on ADP-induced platelet aggregation, from the venom of Protobothrops elegans (Sakishima-habu).
Topics: Adenosine Diphosphate; Animals; Biotinylation; Collagen; Crotalid Venoms; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Fibrinogen; In Vitro Techniques; Integrin beta3; Isoelectric Focusing; Molecular Weight; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoprotein IIb; Rabbits; Ristocetin; Trimeresurus | 2009 |
Effect of quercetin on platelet spreading on collagen and fibrinogen and on multiple platelet kinases.
Topics: Adenosine Diphosphate; Blood Platelets; Collagen; Fibrinogen; Humans; Integrins; Phosphatidylinositol 3-Kinases; Platelet Adhesiveness; Protein Kinase Inhibitors; Protein Kinases; Quercetin; Signal Transduction; Thromboxane A2 | 2010 |
Pneumococcal association to platelets is mediated by soluble fibrin and supported by thrombospondin-1.
Topics: Adenosine Diphosphate; Blood Platelets; Cell Adhesion; Cells, Cultured; Fibrin; Fibrinogen; Host-Pathogen Interactions; Humans; Platelet Activation; Respiratory Tract Infections; Streptococcal Infections; Streptococcus pneumoniae; Thrombin; Thrombospondin 1 | 2009 |
Normal filopodia extension in VASP-deficient platelets upon activation by adhesive matrices or soluble agonists.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Blood Platelets; Cell Adhesion Molecules; Cells, Cultured; Extracellular Matrix; Fibrinogen; Hemostasis; Mice; Mice, Knockout; Microfilament Proteins; Phosphoproteins; Platelet Activation; Pseudopodia; Thromboxane A2; von Willebrand Factor | 2009 |
Cloning and identification of a novel P-II class snake venom metalloproteinase from Gloydius halys.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Animals; Base Sequence; Biological Assay; Caseins; Cations, Divalent; Cattle; Cloning, Molecular; Electrophoresis, Polyacrylamide Gel; Fibrinogen; Fibrinolysis; Hydrogen-Ion Concentration; Metalloproteases; Molecular Sequence Data; Platelet Aggregation; Protease Inhibitors; Protein Folding; Sequence Analysis, DNA; Snake Venoms; Temperature; Viperidae | 2010 |
Fibrinogen interaction with human platelets: effect of other coagulation factors, prostaglandins and platelet inhibitors.
Topics: Adenosine Diphosphate; Blood Coagulation; Blood Coagulation Factors; Blood Platelets; Fibrinogen; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandins; Receptors, Fibrinogen; Recombinant Proteins; Thromboxane A2 | 1983 |
The role of fibrinogen in aggregation of platelets in burn injury.
Topics: Acute Disease; Adenosine Diphosphate; Blood Platelets; Burns; Fibrinogen; Humans; Oxidation-Reduction; Platelet Aggregation | 2010 |
Platelet adhesion and intracellular calcium levels in antigen-challenged rats.
Topics: Adenosine Diphosphate; Animals; Bronchoalveolar Lavage Fluid; Calcium; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrinogen; Immunoglobulin E; Inflammation; Lung; Male; Ovalbumin; Platelet Adhesiveness; Rats; Rats, Wistar; Thrombin; Thrombocytopenia; Time Factors | 2010 |
Platelet activation patterns in platelet size sub-populations: differential responses to aspirin in vitro.
Topics: Acid Phosphatase; Adenosine Diphosphate; Arachidonic Acid; Aspirin; Blood Platelets; Cell Size; Cells, Cultured; Fibrinogen; Humans; Isoenzymes; P-Selectin; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Tartrate-Resistant Acid Phosphatase; Thromboxane B2; von Willebrand Factor | 2010 |
Characterization of canine platelet adhesion to extracellular matrix proteins.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Collagen; Dogs; Extracellular Matrix Proteins; Fibrinogen; Male; Platelet Adhesiveness; Time Factors | 2011 |
Whole blood, flow-chamber studies in real-time indicate a biphasic role for thymosin β-4 in platelet adhesion.
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Collagen; Dimethylpolysiloxanes; Dose-Response Relationship, Drug; Fibrinogen; Humans; Immobilized Proteins; Kinetics; Platelet Activation; Platelet Adhesiveness; Platelet Function Tests; Protein Binding; Thymosin; Time Factors | 2010 |
Association between inflammatory biomarkers and platelet aggregation in patients under chronic clopidogrel treatment.
Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Aspirin; C-Reactive Protein; Cardiovascular Diseases; Chi-Square Distribution; Clopidogrel; Drug Administration Schedule; Drug Therapy, Combination; Female; Fibrinogen; Germany; Humans; Inflammation Mediators; Leukocyte Count; Linear Models; Logistic Models; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Retrospective Studies; Risk Assessment; Risk Factors; Stents; Ticlopidine; Time Factors; Treatment Outcome | 2010 |
Antiplatelet effects of Spatholobus suberectus via inhibition of the glycoprotein IIb/IIIa receptor.
Topics: Adenosine Diphosphate; Animals; Asia, Eastern; Collagen; Dose-Response Relationship, Drug; Epinephrine; Fabaceae; Female; Fibrinogen; Humans; Mice; Mice, Inbred ICR; Phytotherapy; Plant Extracts; Plant Stems; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet-Rich Plasma; Thromboembolism; Thromboxane A2 | 2011 |
Decoration of fibrinogen γ-chain peptide on adenosine diphosphate-encapsulated liposomes enhances binding of the liposomes to activated platelets.
Topics: Adenosine Diphosphate; Blood Platelets; Fibrinogen; Hemostasis; Humans; Inhibitory Concentration 50; Liposomes; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding | 2011 |
Increased nitric oxide production in platelets from severe chronic renal failure patients.
Topics: Adenosine Diphosphate; Arginine; Blood Platelets; Case-Control Studies; Collagen; Cyclic GMP; Female; Fibrinogen; Humans; Inflammation; Kidney Failure, Chronic; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Platelet Aggregation | 2011 |
The periodontal anaerobe Porphyromonas gingivalis induced platelet activation and increased aggregation in whole blood by rat model.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Blood Platelets; Disease Models, Animal; Fibrinogen; Flow Cytometry; Humans; Male; P-Selectin; Periodontitis; Platelet Activation; Platelet Aggregation; Porphyromonas gingivalis; Rats; Rats, Wistar | 2011 |
Potentiation by adrenaline of agonist-induced responses in normal human platelets in vitro.
Topics: Adenosine Diphosphate; Blood Platelets; Cell Shape; Cells, Cultured; Chromatography, Thin Layer; Collagen; Drug Synergism; Edetic Acid; Eicosanoic Acids; Electrophoresis, Polyacrylamide Gel; Epinephrine; Fibrinogen; Hexosaminidases; Humans; Phosphorylation; Platelet Aggregation; Platelet-Rich Plasma; Receptors, Thromboxane A2, Prostaglandin H2; Thrombin | 2011 |
Evidence of platelet activation at medically used hypothermia and mechanistic data indicating ADP as a key mediator and therapeutic target.
Topics: Adenosine Diphosphate; Analysis of Variance; Animals; Antigens, CD; Apyrase; Blood Platelets; Fibrinogen; Fibrinolytic Agents; Humans; Hydrolysis; Hypothermia, Induced; Leukopenia; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; P-Selectin; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIb-IX Complex; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Recombinant Proteins; Thrombocytopenia; Thrombosis; von Willebrand Factor | 2011 |
Platelet activation, oxidative stress and overexpression of inducible nitric oxide synthase in moderate heart failure.
Topics: Adenosine Diphosphate; Arginine; Blood Platelets; C-Reactive Protein; Case-Control Studies; Collagen; Female; Fibrinogen; Heart Failure; Humans; Inflammation; Male; Middle Aged; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Platelet Activation; Platelet Aggregation; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2011 |
Mechanism of anti-platelet activity of Oligoporus tephroleucus oligoporin A: involvement of extracellular signal-regulated kinase phosphorylation and cyclic nucleotide elevation.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Calcium; Cyclic AMP; Cyclic GMP; Extracellular Signal-Regulated MAP Kinases; Fibrinogen; Glucosides; Humans; Male; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Rats; Rats, Sprague-Dawley; Signal Transduction; Triterpenes | 2012 |
TA-2, a thrombin-like enzyme from the Chinese white-lipped green pitviper (Trimeresurus albolabris): isolation, biochemical and biological characterization.
Topics: Adenosine Diphosphate; Animals; Cations, Divalent; Cattle; China; Collagen; Crotalid Venoms; Enzyme Stability; Fibrinogen; Fibrinopeptide A; Fibrinopeptide B; Glycoproteins; Humans; Hydrogen-Ion Concentration; Molecular Weight; Platelet Aggregation; Proteolysis; Substrate Specificity; Thrombin; Tosylarginine Methyl Ester; Trimeresurus | 2012 |
BF066, a novel dual target antiplatelet agent without significant bleeding.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Arterioles; Chlorides; Collagen; Ferric Compounds; Fibrinogen; Hemorrhage; Humans; Immobilized Proteins; Mice; Mice, Inbred C57BL; Oligopeptides; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptor, Adenosine A2A; Thrombin; Thrombosis | 2012 |
Fibrinogen γ-chain peptide-coated, ADP-encapsulated liposomes rescue thrombocytopenic rabbits from non-compressible liver hemorrhage.
Topics: Acute Disease; Adenosine Diphosphate; Animals; Blood Coagulation Tests; Blood Platelets; Disease Models, Animal; Feasibility Studies; Fibrinogen; Hemorrhage; Hemostasis; Hemostatics; Liposomes; Liver Diseases; Male; Microscopy, Immunoelectron; Oligopeptides; Platelet Aggregation; Platelet Count; Rabbits; Thrombocytopenia; Time Factors; Wounds, Penetrating | 2012 |
Aged garlic extract inhibits platelet activation by increasing intracellular cAMP and reducing the interaction of GPIIb/IIIa receptor with fibrinogen.
Topics: Adenosine Diphosphate; Cyclic AMP; Dose-Response Relationship, Drug; Fibrinogen; Flow Cytometry; Garlic; Humans; In Vitro Techniques; Plant Extracts; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex | 2012 |
Generation of functional platelets from canine induced pluripotent stem cells.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Cell Differentiation; Cells, Cultured; Dogs; Embryo, Mammalian; Embryoid Bodies; Fibrinogen; Fibroblasts; Gene Expression; Genetic Vectors; Induced Pluripotent Stem Cells; Intercellular Signaling Peptides and Proteins; Kruppel-Like Transcription Factors; Lentivirus; Megakaryocytes; Platelet Membrane Glycoprotein IIb; Protein Binding; Thrombin | 2013 |
Effects of prolactin on platelet activation and blood clotting.
Topics: Adenosine Diphosphate; Adult; Biomarkers; Blood Coagulation; Blood Platelets; Carrier Proteins; Case-Control Studies; Female; Fibrinogen; Gene Expression; Humans; Hyperprolactinemia; Middle Aged; P-Selectin; Peptides; Platelet Activation; Prolactin; Receptors, Thrombin; Recombinant Proteins | 2013 |
Pharmacokinetic study of the structural components of adenosine diphosphate-encapsulated liposomes coated with fibrinogen γ-chain dodecapeptide as a synthetic platelet substitute.
Topics: Adenosine Diphosphate; Animals; Blood Substitutes; Dose-Response Relationship, Drug; Fibrinogen; Humans; Liposomes; Male; Mice; Oligopeptides; Rabbits; Rats; Rats, Sprague-Dawley; Tissue Distribution | 2013 |
Contact- and agonist-regulated microvesiculation of human platelets.
Topics: Adenosine Diphosphate; Aspirin; Blood Platelets; Cell Shape; Cell-Derived Microparticles; Clopidogrel; Fibrinogen; Humans; Microscopy, Atomic Force; Peptide Fragments; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 2013 |
Pharmacokinetic study of adenosine diphosphate-encapsulated liposomes coated with fibrinogen γ-chain dodecapeptide as a synthetic platelet substitute in an anticancer drug-induced thrombocytopenia rat model.
Topics: Adenosine Diphosphate; Animals; Antineoplastic Agents; Blood Platelets; Blood Substitutes; Busulfan; Fibrinogen; Liposomes; Liver; Male; Rats; Rats, Sprague-Dawley; Spleen; Thrombocytopenia | 2013 |
Adenovirus type 3 induces platelet activation in vitro.
Topics: Adenosine Diphosphate; Adenoviridae; Anti-Bacterial Agents; Blood Platelets; Fibrinogen; Humans; P-Selectin; Platelet Activation; Platelet Aggregation; Platelet Count; Platelet Membrane Glycoprotein IIb; Ristocetin | 2014 |
The integrin antagonist, cilengitide, is a weak inhibitor of αIIbβ3 mediated platelet activation and inhibits platelet adhesion under flow.
Topics: Adenosine Diphosphate; Blood Platelets; Collagen; Endothelial Cells; Fibrinogen; Humans; P-Selectin; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Receptors, Thrombin; Snake Venoms | 2015 |
Cordycepin-enriched WIB801C from Cordyceps militaris inhibits ADP-induced [Ca(2+)] i mobilization and fibrinogen binding via phosphorylation of IP 3R and VASP.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Diphosphate; Adenosine Triphosphate; Blood Platelets; Calcium; Calcium Signaling; Cell Adhesion Molecules; Cordyceps; Cyclic AMP; Cyclooxygenase 1; Deoxyadenosines; Dose-Response Relationship, Drug; Fibrinogen; Herb-Drug Interactions; Humans; Inositol 1,4,5-Trisphosphate Receptors; Microfilament Proteins; Phosphoproteins; Phosphorylation; Plant Extracts; Platelet Aggregation; Platelet Aggregation Inhibitors; Thionucleotides; Thromboxane A2; Thromboxane-A Synthase | 2015 |
Treatment with fibrinogen γ-chain peptide-coated, adenosine 5'-diphosphate-encapsulated liposomes as an infusible hemostatic agent against active liver bleeding in rabbits with acute thrombocytopenia.
Topics: Acute Disease; Adenosine Diphosphate; Animals; Blood Coagulation; Fibrinogen; Hemorrhage; Liposomes; Liver; Male; Platelet Aggregation Inhibitors; Rabbits; Thrombocytopenia | 2015 |
Effect of Repeated Injections of Adenosine Diphosphate-Encapsulated Liposomes Coated with a Fibrinogen γ-Chain Dodecapeptide Developed as a Synthetic Platelet Substitute on Accelerated Blood Clearance in a Healthy and an Anticancer Drug-Induced Thrombocyt
Topics: Adenosine Diphosphate; Animals; Antineoplastic Agents; Blood Platelets; Blood Substitutes; Fibrinogen; Half-Life; Immunoglobulin M; Injections; Liposomes; Male; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Thrombocytopenia | 2015 |
Relationship between the Increased Haemostatic Properties of Blood Platelets and Oxidative Stress Level in Multiple Sclerosis Patients with the Secondary Progressive Stage.
Topics: Adenosine Diphosphate; Blood Platelets; Case-Control Studies; Collagen; Female; Fibrinogen; Hemostatics; Humans; Male; Middle Aged; Multiple Sclerosis; Oxidative Stress; Platelet Adhesiveness; Platelet-Rich Plasma; Superoxides; Thrombin | 2015 |
Preventive Effect of Aspirin Eugenol Ester on Thrombosis in κ-Carrageenan-Induced Rat Tail Thrombosis Model.
Topics: Adenosine Diphosphate; Animals; Aspirin; Blood Platelets; Carrageenan; Disease Models, Animal; Erythrocyte Count; Erythrocytes; Eugenol; Fibrinogen; Hemoglobins; Male; Platelet Aggregation Inhibitors; Platelet Count; Prothrombin Time; Rats; Rats, Wistar; Thrombosis | 2015 |
Viscoelastic measurements of platelet function, not fibrinogen function, predicts sensitivity to tissue-type plasminogen activator in trauma patients.
Topics: Adenosine Diphosphate; Adult; Biomarkers; Blood Platelets; Blood Viscosity; Calcium; Elasticity; Female; Fibrinogen; Fibrinolysis; Fibrinolytic Agents; Humans; Injury Severity Score; Linear Models; Male; Middle Aged; Multivariate Analysis; Patient Selection; Platelet Function Tests; Predictive Value of Tests; Prospective Studies; Thrombolytic Therapy; Tissue Plasminogen Activator; Treatment Outcome; Wounds and Injuries | 2015 |
Hemocompatibility evaluation in vitro of methoxy polyethyleneglycol-polycaprolactone copolymer solutions.
Topics: Adenosine Diphosphate; Arachidonic Acid; Blood Coagulation; Cell Shape; Circular Dichroism; Complement Activation; Complement C3a; Erythrocytes; Fibrinogen; Hemolysis; Hemorheology; Humans; Kinetics; Materials Testing; Partial Thromboplastin Time; Platelet Aggregation; Polyesters; Polyethylene Glycols; Prothrombin Time; Solutions; Spectrometry, Fluorescence; Thrombelastography; Thromboxane B2 | 2016 |
Effect of physical training on indices of platelet aggregation and fibrinogen concentration in patients with chronic heart failure.
Topics: Adenosine Diphosphate; Aged; Cardiac Rehabilitation; Chronic Disease; Dance Therapy; Epinephrine; Exercise Therapy; Female; Fibrinogen; Heart Failure; Humans; Male; Platelet Aggregation; Time Factors | 2015 |
Fibrinogen γ-Chain Peptide-Coated Adenosine 5' Diphosphate-Encapsulated Liposomes Rescue Mice From Lethal Blast Lung Injury via Adenosine Signaling.
Topics: Adenosine; Adenosine Diphosphate; Animals; Blast Injuries; Disease Models, Animal; Fibrinogen; Liposomes; Lung Injury; Male; Mice; Mice, Inbred C57BL; Oligopeptides; Platelet Aggregation Inhibitors; Signal Transduction | 2016 |
Platelet responses to agonists in a cohort of highly characterised platelet donors are consistent over time.
Topics: Adenosine Diphosphate; Adult; Blood Donors; Blood Platelets; Carrier Proteins; Cohort Studies; Female; Fibrinogen; Flow Cytometry; Humans; Male; Middle Aged; P-Selectin; Peptides; Platelet Activation; Platelet Function Tests; Protein Binding | 2017 |
Platelet reactivity in thromboelastometry. Revision of the FIBTEM test: a basic study.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Aspirin; Blood Coagulation Tests; Blood Platelets; Collagen; Cytochalasin D; Female; Fibrin; Fibrinogen; Humans; Integrin beta3; Male; Oligopeptides; Platelet Activation; Platelet Aggregation; Platelet Membrane Glycoprotein IIb; Primary Cell Culture; Thrombelastography | 2017 |
The role of adenosine diphosphate mediated platelet responsiveness for the stability of platelet integrity in citrated whole blood under ex vivo conditions.
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Cell Adhesion Molecules; Cell Survival; Citric Acid; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Female; Fibrinogen; Gene Expression Regulation; Humans; Male; Microfilament Proteins; P-Selectin; Peptide Fragments; Phosphoproteins; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Primary Cell Culture; Protein Binding; Receptors, Purinergic P2X1; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12 | 2017 |
Inhibitory Effect of Flavonolignans on the P2Y12 Pathway in Blood Platelets.
Topics: Adenosine Diphosphate; Blood Platelets; Cell Adhesion Molecules; Fibrinogen; Flavonolignans; Humans; Microfilament Proteins; Phosphoproteins; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet-Rich Plasma; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Signal Transduction; Silybin; Silymarin | 2018 |
Platelets retain inducible alpha granule secretion by P-selectin expression but exhibit mechanical dysfunction during trauma-induced coagulopathy.
Topics: Adenosine Diphosphate; Adult; Blood Coagulation Disorders; Blood Platelet Disorders; Blood Platelets; Cytoskeleton; Fibrinogen; Humans; Middle Aged; P-Selectin; Phenotype; Platelet Aggregation; Platelet Count; Platelet Function Tests; Prospective Studies; Wounds and Injuries; Young Adult | 2019 |
RGD-independent binding of Russell's Viper venom Kunitz-type protease inhibitors to platelet GPIIb/IIIa receptor.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Chymotrypsin; Collagen; Fibrinogen; Goats; Humans; Molecular Docking Simulation; Oligopeptides; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Spectrometry, Fluorescence; Trypsin Inhibitor, Kunitz Soybean; Viper Venoms | 2019 |
Combination therapy using fibrinogen γ-chain peptide-coated, ADP-encapsulated liposomes and hemoglobin vesicles for trauma-induced massive hemorrhage in thrombocytopenic rabbits.
Topics: Adenosine Diphosphate; Animals; Blood Substitutes; Disease Models, Animal; Drug Therapy, Combination; Fibrinogen; Hemoglobins; Hemorrhage; Liposomes; Oligopeptides; Rabbits; Wounds and Injuries | 2019 |
The role of proteasome activity for activating and inhibitory signalling in human platelets.
Topics: Adenosine Diphosphate; Blood Platelets; Bortezomib; Fibrinogen; Humans; P-Selectin; Phosphorylation; Platelet Activation; Platelet Aggregation; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Signal Transduction | 2019 |
Predictive Modeling of Type 1 Diabetes Stages Using Disparate Data Sources.
Topics: Adenosine Diphosphate; Adolescent; Ascorbic Acid; Autoimmunity; Biomarkers; Butyrates; Case-Control Studies; Child; Child, Preschool; Diabetes Mellitus, Type 1; Female; Fibrinogen; Humans; Infant; Male; Mannose; Models, Biological; Polymorphism, Genetic; Protein Tyrosine Phosphatase, Non-Receptor Type 22; Young Adult | 2020 |
Therapeutic potential of fibrinogen γ-chain peptide-coated, ADP-encapsulated liposomes as a haemostatic adjuvant for post-cardiopulmonary bypass coagulopathy.
Topics: Adenosine Diphosphate; Adjuvants, Pharmaceutic; Animals; Blood Coagulation; Blood Coagulation Disorders; Cardiopulmonary Bypass; Fibrinogen; Hemostatics; Liposomes; Platelet Aggregation; Rabbits | 2020 |
In vitro thrombus formation and in vivo hemostasis mediated by platelets irradiated with bactericidal ultraviolet C from xenon flash under flow conditions.
Topics: Adenosine Diphosphate; Animals; Bacteria; Blood Platelets; Collagen; Fibrinogen; Hemostasis; Humans; Male; Mean Platelet Volume; Microscopy, Fluorescence; Models, Animal; Platelet Glycoprotein GPIb-IX Complex; Platelet Glycoprotein GPIIb-IIIa Complex; Plateletpheresis; Rabbits; Thrombosis; Ultraviolet Rays; Xenon | 2021 |
Platelet SHARPIN regulates platelet adhesion and inflammatory responses through associations with αIIbβ3 and LUBAC.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Cytoskeletal Proteins; Fibrinogen; Inflammation; Mice; Nerve Tissue Proteins; NF-kappa B; Platelet Glycoprotein GPIIb-IIIa Complex; Talin; Ubiquitination | 2022 |
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; B7-H1 Antigen; Biomarkers, Tumor; Blood Platelets; Fibrinogen; Humans; Lymphoma, Large B-Cell, Diffuse; Mice; Mice, Inbred C57BL; Neoplasm Recurrence, Local; Platelet Adhesiveness; Prognosis; Programmed Cell Death 1 Receptor; Thrombin | 2022 |
N-Stearoylethanolamine Inhibits Integrin-Mediated Activation, Aggregation, and Adhesion of Human Platelets.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Epinephrine; Ethanolamines; Fibrinogen; Humans; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Rats; Ristocetin; Stearic Acids | 2022 |
Ticagrelor versus Clopidogrel in the Dual Antiplatelet Regimen for Unruptured Intracranial Aneurysm Treated with Stent-Assisted Coil Embolization: A Single-Center Cohort Study.
Topics: Adenosine Diphosphate; Clopidogrel; Cohort Studies; Embolization, Therapeutic; Fibrinogen; Humans; Intracranial Aneurysm; Platelet Aggregation Inhibitors; Stents; Ticagrelor; Treatment Outcome | 2023 |
In vitro study on the effect of fibrinogen γ-chain peptide-coated ADP-encapsulated liposomes on postcardiopulmonary bypass coagulopathy using patient blood.
Topics: Adenosine Diphosphate; Animals; Blood Coagulation Disorders; Blood Platelets; Cardiopulmonary Bypass; Fibrinogen; Hemorrhage; Humans; Liposomes; Peptides; Platelet Aggregation; Rabbits | 2023 |
Hemoglobin Concentration and Viscoelastic Tests: Remember to Consider Fibrinogen and Platelets.
Topics: Adenosine Diphosphate; Blood Coagulation; Blood Platelets; Fibrinogen; Hemoglobins; Hemostatics | 2023 |
Atorvastatin-mediated inhibition of prenylation of Rab27b and Rap1a in platelets attenuates their prothrombotic capacity and modulates clot structure.
Topics: Adenosine Diphosphate; Atorvastatin; Blood Platelets; Fibrinogen; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Prenylation; rab GTP-Binding Proteins; rap1 GTP-Binding Proteins; Thrombosis | 2023 |