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adenosine diphosphate and diadenosine tetraphosphate

adenosine diphosphate has been researched along with diadenosine tetraphosphate in 41 studies

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-199013 (31.71)18.7374
1990's13 (31.71)18.2507
2000's12 (29.27)29.6817
2010's3 (7.32)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jacobson, KA; Jarvis, MF; Williams, M1
Blackburn, GM; Hagemann, J; Hohmeier, N; Lempka, M; Verspohl, EJ1
Barr, HM; Camden, J; Eliahu, S; Fischer, B; Weisman, GA1
Blackburn, GM; Gao, MJ; Kim, B; Taylor, G; Zamecnik, PC1
Günther Sillero, MA; Sillero, A; Wasternack, C1
Bertics, PJ; Leventhal, PS1
Hoyle, CH1
Delicado, EG; Miras-Portugal, MT; Rodriguez del Castillo, A; Torres, M1
Barnes, LD; Garrison, PN; Mumford, CH; Robinson, AK1
Lüthje, J; Ogilvie, A2
Lüthje, J; Miller, D; Ogilvie, A1
Baringer, J; Lüthje, J; Ogilvie, A1
Alderson, T1
Drum, CC; Levy, BT; Maness, PF; Sorge, LK1
Barnekow, A1
Guranowski, A; Holler, E; Jakubowski, H1
Hilderman, RH1
Jakob, P; Ogilvie, A1
Gekeler, V; Hamprecht, K; Probst, H1
Cobbold, PH; Dixon, CJ; Green, AK1
Hankin, S; Mayers, E; McLennan, AG; Powls, R; Prescott, M; Thorne, NM1
Castro, E; Delicado, EG; Miras-Portugal, MT; Sen, RP1
Günther Sillero, MA; Ortiz, B; Sillero, A1
Díaz-Rey, MA; Miras-Portugal, MT; Pintor, J1
Hatano, N; Iwata, K; Kimura, T; Kurosaki, Y; Nakajima, H; Nakayama, T; Wada, M; Yamaura, T1
Berden, JA; Hartog, AF1
Culic, O; Lemmens, R; Teuchy, H; Vanduffel, L1
Figarella, C; Kammouni, W; Merten, MD; Picher, M; Saleh, A1
Breittmayer, JP; Frelin, C; Vigne, P1
Harden, TK; Herold, CL; Kennedy, C; Nicholas, RA; Qi, AD1
Aguilar, JS; Oaknin, S; Ramos, A; Rodríguez-Ferrer, CR; Rotllán, P1
Claes, P; Grobben, B; Roymans, D; Slegers, H; Van Kolen, K1
Barnes, A; Boughtflower, R; Camacho, J; Cousens, D; Marshall, F; Patel, K; Paterson, C1
Laubinger, W; Reiser, G; Wang, H; Welte, T1
Bellezza, I; Castellini, C; Liguori, L; Minelli, A; Renieri, T1
Maier, T; Schultz-Heienbrok, R; Sträter, N1
Günthner, T; Jalkanen, S; Jankowski, J; Jankowski, V; Yegutkin, GG; Zidek, W1
Albright, RA; Braddock, DT; Cao, W; Chang, WC; De La Cruz, EM; Liu, L; Ornstein, DL; Redick, ME; Robert, D; Young, JI1
Barnard, MR; Chang, H; Dix, EJ; Frelinger, AL; Li, YF; Michelson, AD; Wright, GE; Yanachkov, IB1
Boeynaems, JM; Communi, D; Gonzalez, NS; Labouret, C; Le Poul, E; Marteau, F; Savi, P1

Reviews

2 review(s) available for adenosine diphosphate and diadenosine tetraphosphate

ArticleYear
Purine and pyrimidine (P2) receptors as drug targets.
    Journal of medicinal chemistry, 2002, Sep-12, Volume: 45, Issue:19

    Topics: Adenosine Triphosphate; Animals; Drug Design; Humans; Ligands; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyrimidines; Receptors, Purinergic P2; Uridine Triphosphate

2002
Formaldehyde-induced mutagenesis: a novel mechanism for its action.
    Mutation research, 1985, Volume: 154, Issue:2

    Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Animals; Cell Transformation, Neoplastic; Cricetinae; Dinucleoside Phosphates; DNA Repair; Drosophila melanogaster; Drug Resistance; Female; Formaldehyde; Larva; Male; Mammals; Mesocricetus; Mice; Mutation; Oogenesis; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Spermatogenesis; Stress, Physiological

1985

Other Studies

39 other study(ies) available for adenosine diphosphate and diadenosine tetraphosphate

ArticleYear
Synthetic, nondegradable diadenosine polyphosphates and diinosine polyphosphates: their effects on insulin-secreting cells and cultured vascular smooth muscle cells.
    Journal of medicinal chemistry, 2003, Apr-10, Volume: 46, Issue:8

    Topics: 3T3 Cells; Animals; Cell Division; Cells, Cultured; Dinucleoside Phosphates; In Vitro Techniques; Insulin; Insulin Secretion; Mice; Muscle, Smooth, Vascular; Protein Binding; Rats; Stereoisomerism; Structure-Activity Relationship; Thymidine

2003
A novel insulin secretagogue based on a dinucleoside polyphosphate scaffold.
    Journal of medicinal chemistry, 2010, Mar-25, Volume: 53, Issue:6

    Topics: Alkaline Phosphatase; Animals; Blood Glucose; Cell Line, Tumor; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Fasting; Humans; Insulin; Insulin Secretion; Male; Molecular Structure; Purinergic P2 Receptor Agonists; Rats; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Serum; Structure-Activity Relationship

2010
Analogues of diadenosine 5',5'''-P1,P4-tetraphosphate (Ap4A) as potential anti-platelet-aggregation agents.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Mar-15, Volume: 89, Issue:6

    Topics: Adenosine Diphosphate; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Kinetics; Platelet Aggregation; Platelet Aggregation Inhibitors; Structure-Activity Relationship

1992
Diadenosine polyphosphates inhibit the action of ribonucleotide reductase on ADP.
    Biochemistry international, 1991, Volume: 23, Issue:1

    Topics: Adenosine Diphosphate; Cell Membrane Permeability; Chromatography, Gel; Chromatography, High Pressure Liquid; Dinucleoside Phosphates; Enzyme Inhibitors; Oxidation-Reduction; Ribonucleotide Reductases; Yeasts

1991
Kinetic analysis of protein kinase C: product and dead-end inhibition studies using ADP, poly(L-lysine), nonhydrolyzable ATP analogues, and diadenosine oligophosphates.
    Biochemistry, 1991, Feb-05, Volume: 30, Issue:5

    Topics: Adenosine Diphosphate; Adenylyl Imidodiphosphate; Animals; Brain; Dinucleoside Phosphates; In Vitro Techniques; Kinetics; Polylysine; Protein Kinase C; Rats

1991
Pharmacological activity of adenine dinucleotides in the periphery: possible receptor classes and transmitter function.
    General pharmacology, 1990, Volume: 21, Issue:6

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adrenal Medulla; Animals; Blood Platelets; Chromaffin Granules; Dinucleoside Phosphates; Humans; NAD; NADP; Receptors, Purinergic

1990
Subcellular distribution studies of diadenosine polyphosphates--Ap4A and Ap5A--in bovine adrenal medulla: presence in chromaffin granules.
    Journal of neurochemistry, 1988, Volume: 51, Issue:6

    Topics: Adenosine Diphosphate; Adenosine Kinase; Adenosine Monophosphate; Adenosine Triphosphate; Adenylate Kinase; Adrenal Medulla; Animals; Cattle; Chromaffin Granules; Chromaffin System; Chromatography, High Pressure Liquid; Cytosol; Dinucleoside Phosphates; Phosphoric Monoester Hydrolases

1988
Assay of diadenosine tetraphosphate hydrolytic enzymes by boronate chromatography.
    Analytical biochemistry, 1985, Volume: 144, Issue:1

    Topics: Acid Anhydride Hydrolases; Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Boron Compounds; Chromatography, Ion Exchange; Dinucleoside Phosphates; Phosphoric Diester Hydrolases; Phosphoric Monoester Hydrolases; Physarum

1985
Catabolism of Ap3A and Ap4A in human plasma. Purification and characterization of a glycoprotein complex with 5'-nucleotide phosphodiesterase activity.
    European journal of biochemistry, 1985, May-15, Volume: 149, Issue:1

    Topics: Adenine Nucleotides; Adenosine Diphosphate; Chromatography; Dinucleoside Phosphates; Electrophoresis, Polyacrylamide Gel; Humans; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Metals; Molecular Weight; Nucleotides; Phosphodiesterase I; Phosphoric Diester Hydrolases; Substrate Specificity

1985
Unproportionally high concentrations of diadenosine triphosphate (Ap3A) and diadenosine tetraphosphate (Ap4A) in heavy platelets. Consequences for in vitro studies with human platelets.
    Blut, 1987, Volume: 54, Issue:4

    Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Blood Platelets; Cell Separation; Centrifugation, Density Gradient; Dinucleoside Phosphates; Humans; Povidone; Silicon Dioxide

1987
Effects of diadenosine triphosphate (Ap3A) and diadenosine tetraphosphate (Ap4A) on platelet aggregation in unfractionated human blood.
    Blut, 1985, Volume: 51, Issue:6

    Topics: Adenine Nucleotides; Adenosine Diphosphate; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Heparin; Humans; Kinetics; Platelet Aggregation; Platelet Count

1985
Differential inhibition of cellular and viral pp60src kinase by P1,P4-di(adenosine-5')tetraphosphate.
    Molecular and cellular biology, 1983, Volume: 3, Issue:10

    Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antibodies, Neoplasm; Avian Sarcoma Viruses; Binding Sites; Chick Embryo; Dinucleoside Phosphates; Immunoglobulin Heavy Chains; Oncogene Protein pp60(v-src); Phosphoproteins; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins pp60(c-src); Viral Proteins

1983
Effect of several nucleotides on the phosphorylating activities of the Rous-sarcoma-virus transforming protein pp60v-src and its cellular homologue, pp60c-src.
    Bioscience reports, 1983, Volume: 3, Issue:2

    Topics: Adenine Nucleotides; Adenosine Diphosphate; Animals; Avian Sarcoma Viruses; Cell Transformation, Neoplastic; Cell Transformation, Viral; Chick Embryo; Dinucleoside Phosphates; Guanosine Diphosphate; Mice; Nucleotides; Oncogene Protein pp60(v-src); Phosphorylation; Protein Kinase Inhibitors; Viral Proteins

1983
Catabolism of diadenosine 5',5"'-P1,P4-tetraphosphate in procaryotes. Purification and properties of diadenosine 5',5"'-P1,P4-tetraphosphate (symmetrical) pyrophosphohydrolase from Escherichia coli K12.
    The Journal of biological chemistry, 1983, Dec-25, Volume: 258, Issue:24

    Topics: Acid Anhydride Hydrolases; Adenine Nucleotides; Adenosine Diphosphate; Archaea; Cobalt; Dinucleoside Phosphates; Escherichia coli; Eubacterium; Phosphoric Diester Hydrolases

1983
Characterization of a homogeneous complex of arginyl- and lysyl-tRNA synthetase: zinc and adenosine 5'-phosphate dependent synthesis of diadenosine 5',5'''-P1,P4-tetraphosphate.
    Biochemistry, 1983, Sep-13, Volume: 22, Issue:19

    Topics: Adenine Nucleotides; Adenosine Diphosphate; Amino Acyl-tRNA Synthetases; Animals; Arginine-tRNA Ligase; Dinucleoside Phosphates; Female; Kinetics; Liver; Lysine-tRNA Ligase; Macromolecular Substances; Rats; Zinc

1983
Diadenosine 5',5"'-P1,P3-triphosphate in eukaryotic cells: identification and quantitation.
    Analytical biochemistry, 1983, Oct-15, Volume: 134, Issue:2

    Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Carcinoma, Ehrlich Tumor; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, High Pressure Liquid; Dinucleoside Phosphates; Eukaryotic Cells; Mice

1983
Diadenosine triphosphate (Ap3A) mediates human platelet aggregation by liberation of ADP.
    Biochemical and biophysical research communications, 1984, Feb-14, Volume: 118, Issue:3

    Topics: Adenine Nucleotides; Adenosine Diphosphate; Alkaline Phosphatase; Dinucleoside Phosphates; Humans; Platelet Activating Factor; Platelet Aggregation

1984
Replicon initiation frequency and intracellular levels of ATP, ADP, AMP and of diadenosine 5',5'''-P1,P4-tetraphosphate in ehrlich ascites cells cultured aerobically and anaerobically.
    Biochemical and biophysical research communications, 1983, Jan-27, Volume: 110, Issue:2

    Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aerobiosis; Anaerobiosis; Animals; Carcinoma, Ehrlich Tumor; Cells, Cultured; Dinucleoside Phosphates; DNA, Neoplasm; Mice; Oxygen; Replicon

1983
Cytosolic free Ca2+ oscillations induced by diadenosine 5',5"'-P1,P3-triphosphate and diadenosine 5',5"'-P1,P4-tetraphosphate in single rat hepatocytes are indistinguishable from those induced by ADP and ATP respectively.
    The Biochemical journal, 1995, Sep-01, Volume: 310 ( Pt 2)

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Cytosol; Dinucleoside Phosphates; Diterpenes; Kinetics; Liver; Male; Phorbol 12,13-Dibutyrate; Rats; Rats, Wistar; Time Factors

1995
The green alga Scenedesmus obliquus contains both diadenosine 5',5'''-P1,P4-tetraphosphate (asymmetrical) pyrophosphohydrolase and phosphorylase activities.
    The Biochemical journal, 1994, May-15, Volume: 300 ( Pt 1)

    Topics: Acid Anhydride Hydrolases; Adenine Nucleotides; Adenosine Diphosphate; Cations, Divalent; Chlorophyta; Chromatography, High Pressure Liquid; Dinucleoside Phosphates; Electrophoresis, Polyacrylamide Gel; Fluorides; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Nucleotidyltransferases; Pyrophosphatases; Substrate Specificity

1994
Effect of P2Y agonists on adenosine transport in cultured chromaffin cells.
    Journal of neurochemistry, 1993, Volume: 60, Issue:2

    Topics: Adenosine; Adenosine Diphosphate; Adenylyl Imidodiphosphate; Adrenal Medulla; Animals; Biological Transport; Bradykinin; Carbachol; Cattle; Cells, Cultured; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Kinetics; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Purinergic; Thionucleotides

1993
Specific synthesis of adenosine(5')tetraphospho(5')nucleoside and adenosine(5')oligophospho(5')adenosine (n > 4) catalyzed by firefly luciferase.
    European journal of biochemistry, 1993, Feb-15, Volume: 212, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Coleoptera; Dinucleoside Phosphates; Luciferases

1993
Ap4A and ADP-beta-S binding to P2 purinoceptors present on rat brain synaptic terminals.
    British journal of pharmacology, 1993, Volume: 108, Issue:4

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Binding, Competitive; Brain Chemistry; Cerebral Cortex; Chromatography, High Pressure Liquid; Dinucleoside Phosphates; In Vitro Techniques; Kinetics; Male; Nerve Endings; Rats; Rats, Wistar; Receptors, Purinergic; Synapses; Synaptosomes; Thionucleotides

1993
Disposition of diadenosine 5',5"'-P1,P4-tetraphosphate (Ap4A) in rats.
    Biological & pharmaceutical bulletin, 1995, Volume: 18, Issue:11

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Dinucleoside Phosphates; Half-Life; Injections, Intravenous; Male; Rats; Rats, Wistar

1995
Nucleotide-binding sites in F1-ATPase: different pockets for different types of nucleotide analogues.
    Biochemical Society transactions, 1995, Volume: 23, Issue:4

    Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Binding Sites; Dinucleoside Phosphates; Diphosphates; Kinetics; Mitochondria; Molecular Structure; Protein Conformation; Proton-Translocating ATPases

1995
Regulation of proliferation of LLC-MK2 cells by nucleosides and nucleotides: the role of ecto-enzymes.
    The Biochemical journal, 1996, Jun-01, Volume: 316 ( Pt 2)

    Topics: 5'-Nucleotidase; Acid Anhydride Hydrolases; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Alkaline Phosphatase; Animals; Cell Division; Cell Line; Cell Line, Transformed; Dinucleoside Phosphates; Dipyridamole; Enzyme Inhibitors; HeLa Cells; Humans; Levamisole; Nucleoside-Triphosphatase; Nucleosides; Nucleotides; Suramin; Thymidine; Triazines

1996
Characterization of a diadenosine tetraphosphate-receptor distinct from the ATP-purinoceptor in human tracheal gland cells.
    European journal of pharmacology, 1999, Nov-12, Volume: 384, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Binding, Competitive; Calcium; Cells, Cultured; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Humans; Hydrolysis; Proteinase Inhibitory Proteins, Secretory; Proteins; Receptors, Purinergic P2; Secretory Leukocyte Peptidase Inhibitor; Suramin; Thionucleotides; Trachea

1999
Diadenosine polyphosphates as antagonists of the endogenous P2Y(1) receptor in rat brain capillary endothelial cells of the B7 and B10 clones.
    British journal of pharmacology, 2000, Volume: 129, Issue:7

    Topics: Adenosine Diphosphate; Adenylyl Cyclases; Animals; Brain; Calcium; Cells, Cultured; Clone Cells; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Endothelium, Vascular; Purinergic P2 Receptor Antagonists; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y1

2000
ATP, an agonist at the rat P2Y(4) receptor, is an antagonist at the human P2Y(4) receptor.
    Molecular pharmacology, 2000, Volume: 57, Issue:5

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Dinucleoside Phosphates; Humans; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rats; Receptors, Purinergic P2; Species Specificity; Tumor Cells, Cultured; Uridine Diphosphate

2000
Receptor binding properties of di (1,N6-ethenoadenosine) 5', 5'''-P1, P4-tetraphosphate and its modulatory effect on extracellular glutamate levels in rat striatum.
    Neuroscience letters, 2001, Aug-31, Volume: 309, Issue:3

    Topics: Adenosine Diphosphate; Animals; Corpus Striatum; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Extracellular Space; Glutamic Acid; Hippocampus; Male; Neurotransmitter Agents; Rats; Rats, Wistar; Receptors, Purinergic P2; Thionucleotides

2001
P2Y(AC)(-)-receptor agonists enhance the proliferation of rat C6 glioma cells through activation of the p42/44 mitogen-activated protein kinase.
    British journal of pharmacology, 2001, Volume: 134, Issue:2

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cell Division; Dinucleoside Phosphates; Enzyme Activation; Glioma; Hydrolysis; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Purinergic P2 Receptor Agonists; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2; Thionucleotides; Time Factors; Triazines; Tumor Cells, Cultured

2001
Activity of diadenosine polyphosphates at P2Y receptors stably expressed in 1321N1 cells.
    European journal of pharmacology, 2001, Nov-02, Volume: 430, Issue:2-3

    Topics: Adenosine Diphosphate; Calcium; Carbachol; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Gene Expression; Humans; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y2; Tumor Cells, Cultured; Uridine Triphosphate

2001
P2Y receptor specific for diadenosine tetraphosphate in lung: selective inhibition by suramin, PPADS, Ip5I, and not by MRS-2197.
    European journal of pharmacology, 2003, May-02, Volume: 468, Issue:1

    Topics: Adenosine Diphosphate; Animals; Calcium Channel Blockers; Calcium Signaling; Cells, Cultured; Dinucleoside Phosphates; Epithelial Cells; Humans; Lung; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Suramin

2003
Effects of diadenosine polyphosphates and seminal fluid vesicles on rabbit sperm cells.
    Reproduction (Cambridge, England), 2003, Volume: 125, Issue:6

    Topics: 5'-Nucleotidase; Acrosome Reaction; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Dinucleoside Phosphates; Male; Microscopy, Electron; Polyphosphates; Rabbits; Seminal Vesicles; Sperm Capacitation; Spermatozoa; Type C Phospholipases

2003
A large hinge bending domain rotation is necessary for the catalytic function of Escherichia coli 5'-nucleotidase.
    Biochemistry, 2005, Feb-22, Volume: 44, Issue:7

    Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Monophosphate; Binding Sites; Catalysis; Circular Dichroism; Crystallography, X-Ray; Dinucleoside Phosphates; Disulfides; Dithiothreitol; Escherichia coli Proteins; Hydrolysis; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Oxidation-Reduction; Protein Conformation; Protein Structure, Tertiary; Substrate Specificity

2005
Dinucleotide polyphosphates contribute to purinergic signalling via inhibition of adenylate kinase activity.
    Bioscience reports, 2008, Volume: 28, Issue:4

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylate Kinase; Cells, Cultured; Dinucleoside Phosphates; Humans; Nucleotides; Signal Transduction; Suramin

2008
NPP4 is a procoagulant enzyme on the surface of vascular endothelium.
    Blood, 2012, Nov-22, Volume: 120, Issue:22

    Topics: Adenosine Diphosphate; Adult; Animals; Blood Coagulation; Coagulants; Cyclic Nucleotide Phosphodiesterases, Type 4; Dinucleoside Phosphates; Endothelium, Vascular; Fluorescent Antibody Technique; Humans; Hydrolysis; In Vitro Techniques; Insecta; Phosphoric Diester Hydrolases; Platelet Aggregation; Pyrophosphatases; Tissue Distribution

2012
Modified diadenosine tetraphosphates with dual specificity for P2Y1 and P2Y12 are potent antagonists of ADP-induced platelet activation.
    Journal of thrombosis and haemostasis : JTH, 2012, Volume: 10, Issue:12

    Topics: Adenosine Diphosphate; Dinucleoside Phosphates; Humans; Phosphorylation; Platelet Activation; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12

2012
Pharmacological characterization of the human P2Y13 receptor.
    Molecular pharmacology, 2003, Volume: 64, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cell Membrane; CHO Cells; Cricetinae; Cyclic AMP; Female; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Inositol Phosphates; Kinetics; Receptors, Purinergic P2; Thionucleotides

2003