adenosine diphosphate has been researched along with cyclic gmp in 163 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 57 (34.97) | 18.7374 |
| 1990's | 47 (28.83) | 18.2507 |
| 2000's | 36 (22.09) | 29.6817 |
| 2010's | 19 (11.66) | 24.3611 |
| 2020's | 4 (2.45) | 2.80 |
| Authors | Studies |
|---|---|
| Davidson, MM; Haslam, RJ; McClenaghan, MD | 1 |
| Koyama, D; Ono, T; Tomida, M | 1 |
| Hilgartner, MW; Miller, DR; Schmalzer, EA; Steinherz, PG | 1 |
| Beers, TR; Craig, SP; Innis, MA | 1 |
| Beattie, DS; Kobilinsky, L; Weinstein, BI | 1 |
| Haslam, RJ | 1 |
| Davidson, MM; Davies, T; Haslam, RJ; McClenaghan, MD; Say, A | 1 |
| Krause, EG; Wollenberger, A | 1 |
| Beutler, E; Guinto, E; Johnson, C | 1 |
| Henderson, JF; Smith, CM; Zombor, G | 1 |
| de Jonge, HR; Rosen, OM | 1 |
| Saito, M | 1 |
| Claesson, HE; Malmsten, C | 1 |
| Kobayashi, M; Lust, WD; Passonneau, JV | 1 |
| Demain, AL; Martin, JF | 1 |
| Asano, T; Hidaka, H; Mashimo, N; Motomiya, T; Yamazaki, H | 1 |
| Davidson, MM; Davies, T; Haslam, RJ; Lynham, JA; McClenaghan, MD | 1 |
| Kannagi, R; Koizumi, K | 1 |
| Best, LC; Holland, TK; Jones, PB; Martin, TJ; McGuire, MB; Preston, FE; Russell, RG; Segal, DS | 1 |
| Rodnight, R; Weller, M | 1 |
| Hasimoto, K; King, LE; Solomon, SS | 1 |
| Butt, E; Geiger, J; Nolte, C; Sage, SO; Walter, U | 1 |
| Boulanger, CM; Vanhoutte, PM | 1 |
| Ikeda, M; Kurokawa, K; Maruyama, Y | 1 |
| Brenton, AG; Evans, AM; Harris, FM; Khan, JA; Langridge, JI; Newton, RP; Walton, TJ | 1 |
| Dutra, A; Moncada, S; Radomski, MW; Rees, DD | 1 |
| Belushkina, NN; Severina, IS | 1 |
| Druker, BJ; Oda, A; Salzman, EW; Smith, M | 1 |
| Longo, LD; Pearce, WJ | 1 |
| Ershov, DE; Fedorov, NA; Ishigov, RA; Khadzhiev, AK; Vrzheshch, PV | 1 |
| Nishimura, J; van Breemen, C | 1 |
| Belushkina, NN; Chirkov, YY; Horowitz, JD; Severina, IS; Tyshchuk, IA | 1 |
| Belushkina, NN; Chirkov, IuIu; Severina, IS; Tyshchuk, IA | 1 |
| Mollace, V; Moore, A; Radziszewski, W; Salvemini, D; Vane, J; Willoughby, D | 1 |
| Snaar-Jagalska, BE; Van Haastert, PJ | 1 |
| George, D; Loscalzo, J; Mendelsohn, ME; O'Neill, S | 1 |
| Boulanger, C; Moncada, S; Schini, VB; Vanhoutte, PM | 1 |
| Bühler, FR; Erne, P; Mittelholzer, E; Resink, TJ; Rogg, H | 1 |
| Morgan, RO; Newby, AC | 1 |
| Brayden, JE; Wellman, GC | 1 |
| Comte, J; Gautheron, DC; Godinot, C; Meister, R | 1 |
| Brüne, B; Ullrich, V | 1 |
| Armstrong, RA; Jones, RL; Wilson, NH | 1 |
| Romstedt, K | 1 |
| Lombardini, JB; Tsung, PK | 1 |
| Gries, A; Kostner, GM; Nimpf, J; Wurm, H | 1 |
| Li, YS; Liu, KF; Wang, QC | 1 |
| Hur, KC; Johnson, R; Louis, CF; Mickelson, JR; Turnquist, J | 1 |
| Böhme, E; Jakobs, KH; Mocikat, S | 1 |
| Beug, AG; Ensinck, JW; Little, SA; Williams, RH | 1 |
| Prasad, KN; Vernadakis, A | 1 |
| Field, JB; Yamashita, K | 1 |
| Hayaishi, O; Miyakawa, N; Ueda, K | 1 |
| Kadota, K; Kadota, T | 1 |
| Davis, JW; Hardman, JG; Schultz, G; Schultz, K; Sutherland, EW | 1 |
| Suzuki, I; Wold, WS | 1 |
| Edwards, AM; Elliott, WH | 1 |
| Haarasilta, S; Oura, E | 1 |
| Matsumura, Y; Tan, EM; Vaughan, JH | 1 |
| Chopra, DP; Flaxman, BA; Harper, RA | 1 |
| Dinnendahl, V | 1 |
| Nath, J; Rebhun, LI | 1 |
| Bates, DJ; Mowbray, J; Perrett, D | 1 |
| Cherry, PD; Furchgott, RF; Jothianandan, D | 1 |
| Jones, CJ; Kealey, T; Lee, CM | 1 |
| Berger, SJ; Carter, JG; DeVries, GW; Ferrendelli, JA; Lowry, OH; Passonneau, PN; Schulz, DW | 1 |
| Hyman, AL; Ignarro, LJ; Kadowitz, PJ; Mellion, BT; Ohlstein, EH; Pontecorvo, EG | 1 |
| Jancinová, V; Nosál, R; Petríková, M | 1 |
| Matsuoka, I; Suzuki, T | 1 |
| Bousseau-Lafortune, S; Coquil, JF; Franks, DJ; Hamet, P; Tremblay, J | 1 |
| Astaldi, A; Batenburg-Plenter, AM; Bot, AA; Roos, D; Schoorel, EP; van Schaik, ML; Voetman, AA; Weening, RS; Willems, C; Zeijlemaker, WP | 1 |
| Kadowitz, PJ; Lippton, HL; Myers, CB; Pontecorvo, EG | 1 |
| Gerlach, E; Hiendlmayer, G; Schrader, J; Thompson, CI | 1 |
| Anfossi, G; Cavalot, F; Massucco, P; Mattiello, L; Mularoni, E; Trovati, M | 2 |
| Francis, S; Jaraki, O; Loscalzo, J; Stamler, JS; Strauss, WE | 1 |
| Cohen, RA; Palacino, JJ; Tesfamariam, B; Weisbrod, RM | 1 |
| Chirkov, YY; Horowitz, JD; Naujalis, JI; Sage, RE | 1 |
| Delwaide, PJ | 1 |
| Howlett, AC; Klein, C; Tao, Y | 1 |
| Severina, IS | 1 |
| Cooke, JP; Leung, LL; Singer, AH; Theilmeier, G; Tsao, PS | 1 |
| Adams, HR; Graier, WF; Myers, PR; Parker, JL; Rubin, LJ | 1 |
| Belushkina, NN; Grigoryev, NB; Severina, IS | 1 |
| Hirasawa, Y; Kita, Y; Maeda, K; Nishio, M; Yoshida, K | 1 |
| Cecchi, E; Failli, P; Fazzini, A; Giotti, A; Ruocco, C | 1 |
| Bochkov, VN; Cherkasova, GD; Iurkiv, VA; Pokrovskiĭ, VI | 1 |
| Jaraki, O; Loscalzo, J; Mullins, M; Osborne, JA; Rabbani, LE; Singel, D; Stamler, JS | 1 |
| Francis, SA; Jaraki, O; Keaney, JF; Loscalzo, J; Osborne, JA; Simon, DI; Singel, DJ; Stamler, JS | 1 |
| Drummer, C; Gerzer, R; Ivanova, K; Schaefer, M | 1 |
| Grevelink, SA; Lerner, EA; Loscalzo, J; Youssef, DE | 1 |
| Anfossi, G; Cavalot, F; Massucco, P; Mattiello, L; Mularoni, E; Paoletti, G; Piretto, V; Trovati, M | 1 |
| Lai, PS; Rodriguez, A; Spur, BW; Wong, PY; Yin, K | 1 |
| Asazuma, N; Kume, S; Ozaki, Y; Qi, R; Satoh, K; Yang, LB; Yatomi, Y | 1 |
| Alpert, C; Barnard, MR; Freedman, JE; Keaney, JF; Loscalzo, J; Michelson, AD | 1 |
| Imai, Y; Kitagawa, T; Tomita, T; Tsuyama, S | 1 |
| Bar, J; Elder, MG; Hod, M; Sullivan, MH; Zosmer, A | 1 |
| Franklin, A; Hariawala, MD; Li, J; Sellke, FW; Stamler, A; Tofukuji, M | 1 |
| Ambrósio, AF; Carvalho, AP; Carvalho, CM; Malva, JO; Sequeira, SM | 1 |
| Anfossi, G; Burzacca, S; Cavalot, F; Massucco, P; Mattiello, L; Mularoni, EM; Ponziani, MC; Trovati, M | 1 |
| Hangaishi, M; Hashimoto, Y; Ikari, Y; Kimura, S; Kurokawa, K; Miyata, T; Ohno, M; Taguchi, J; Togo, M; Watanabe, T | 1 |
| Graier, WF; Posch, K; Schmidt, K | 1 |
| Anfossi, G; Cavalot, F; Giori, A; Massucco, P; Mattiello, L; Perna, P; Tassone, F; Trovati, M | 1 |
| Cable, DG; Caccitolo, JA; Daly, RC; Dearani, JA; Mullany, CJ; O'Brien, T; Orszulak, TA; Pfeifer, EA; Schaff, HV | 1 |
| Doi, H; Ikeo, T; Karasawa, T; Katoh, M; Narita, H; Odawara, A; Takagi, M | 1 |
| Chung, JC; Kang, SK; Kim, CH; Kim, SY; Lee, DG; Lee, YC; Park, YG | 1 |
| Gorodeski, GI | 1 |
| Magid, KS; Megson, IL; Shaw, CA; Sogo, N; Webb, DJ | 1 |
| Bilbe, G; Bowler, WB; Buckley, KA; Gallagher, JA; Gaw, A; Hipskind, RA; McKay, G; Wagstaff, SC | 1 |
| Conde, M; Porras, T; Rosado, JA; Sage, SO | 1 |
| Anfossi, G; Balbo, A; Cavalot, F; Massucco, P; Mattiello, L; Russo, I; Trovati, M | 2 |
| Anfossi, G; Cavalot, F; Massucco, P; Mattiello, L; Russo, I; Trovati, M | 1 |
| Kagota, S; Kunitomo, M; Kuno, T; Nakamura, K; Sugiura, R; Tamashiro, A; Yamaguchi, Y | 1 |
| Jaimes, EA; Raij, L; Sweeney, C | 1 |
| Lassila, R; Rissanen, A; Syrjälä, M; Turpeinen, A; Vehkavaara, S; Westerbacka, J; Yki-Järvinen, H | 1 |
| Briones, R; Buvinic, S; Huidobro-Toro, JP | 1 |
| Homer, KL; Wanstall, JC | 1 |
| Díaz-Enrich, MJ; Ibarguren, I; Ramos-Martínez, JI | 1 |
| Anfossi, G; Massucco, P; Mattiello, L; Russo, I; Trovati, M | 2 |
| Dikshit, M; Raghavan, SA; Sharma, P | 1 |
| Greenwood, D; Han, P; Hegg, CC; Huang, W; Lucero, MT | 1 |
| Hobbs, AJ; Moncada, S | 1 |
| Díaz Enrich, MJ; Ibarguren, I | 1 |
| Loiko, EN; Samal, AB; Shulyakovskaya, SM | 1 |
| Farina, M; Frizzo, ME; Lara, DR; Portela, LV; Schmidt, AP; Soares, FA; Souza, DO; Tavares, RG | 1 |
| Akkerman, JW; Greinacher, A; Jedlitschky, G; Kroemer, HK; Lubenow, LE; Nieuwenhuis, HK; Tirschmann, K | 1 |
| Han, MK; Im, MJ; Kim, UH; Park, KH; Rah, SY | 1 |
| Danielewski, O; Schultess, J; Smolenski, A | 1 |
| Abuo-Rahma, Gel D; El-Emam, A; Glusa, E; Horstmann, A; Lehmann, J; Radwan, MF | 1 |
| Farndale, RW; Naseem, KM; Riba, R; Sharifi, M | 1 |
| Chandy, S; Chirkov, YY; Holmes, AS; Horowitz, JD; Kanna, R; Mishra, K | 1 |
| Naseem, KM; Oberprieler, NG; Riba, R; Roberts, W | 1 |
| Graham, AM; Homer-Vanniasinkam, S; Naseem, KM; Oberprieler, NG; Roberts, W | 1 |
| Danielewski, O; Hoffmeister, M; Neumüller, O; Riha, P; Schultess, J; Smolenski, AP | 1 |
| Chudzinski-Tavassi, AM; de Lemos, TL; de Sousa, CM; do Nascimento, NR; Ferreira, MA; Pessoa, OD; Schattner, M; Ventura, JS | 1 |
| Bhattacharya, G; Bhattacharya, R; Bhattacharyya, M; Karmohapatra, SK; Sinha, AK | 1 |
| Arora, S; Chatterjee, S; Kumar, A; Majumder, S; Parmar, VS; Prasad, AK; Raj, HG; Saluja, D; Saso, L; Tyagi, YK | 1 |
| Cheng, KT; Huang, Y; Kwan, HY; Ma, Y; Tang, NL; Yao, X; Yu, S | 1 |
| Anfossi, G; Bonomo, K; Cavalot, F; De Salve, A; Del Mese, P; Doronzo, G; Mattiello, L; Russo, I; Traversa, M; Trovati, M | 1 |
| Chen, Q; Cui, B; Ferro, A; Han, Y; Huang, Y; Ji, Y; Jiang, Q; Liu, N; Liu, Y; Mi, Q; Wang, L; Wu, Y | 1 |
| Laychock, SG; You, H | 1 |
| Brunini, TM; Lugon, JR; Martins, MA; Mendes-Ribeiro, AC; Moss, MB; Pereira, NR; Santos, SF; Siqueira, MA | 1 |
| Coleman Anderson, L; Croce, K; Handy, DE; Jin, RC; Leopold, JA; Loscalzo, J; Mahoney, CE; Ottaviano, F; Tang, SS; Zhang, YY | 1 |
| Chou, DS; Fong, TH; Hsiao, G; Jayakumar, T; Lee, JJ; Lu, WJ; Sheu, JR | 1 |
| Bhatia, S; Medhi, B; Parmar, VS; Prasad, AK; Priya, N; Raj, HG; Singh, P | 1 |
| Joshi, R; Kumar, A; Manral, S; Parmar, VS; Prasad, AK; Raj, HG; Rohil, V; Singh, U; Sinha, R; Sushama, A | 1 |
| Antunes, E; Calixto, MC; Delbin, MA; Lopes-Pires, ME; Marcondes, S; Monteiro, PF; Morganti, RP; Zanesco, A | 1 |
| Cho, JY; Kim, GS; Kim, MJ; Kim, S; Kim, SK; Kim, TH; Lee, IK; Oh, WJ; Park, HJ; Park, JY; Rhee, MH; Seo, GS; Yun, BS | 1 |
| Baraquet, C; Harwood, CS; Murakami, K; Parsek, MR | 1 |
| Chan, WP; Chirkov, YY; Heresztyn, T; Horowitz, JD; Leslie, S; Liberts, EA; Procter, N; Rajendran, S; Willoughby, SR | 1 |
| Chen, WF; Chou, DS; Hsiao, G; Hsieh, CY; Hsu, CY; Jayakumar, T; Lu, WJ; Sheu, JR | 1 |
| Gambaryan, S; Herterich, S; Rukoyatkina, N; Subramanian, H; Walter, U | 1 |
| Chan, MV; Emerson, M; Kirkby, NS; Lundberg, MH; Mitchell, JA; Solomon, AB; Vojnovic, I; Warner, TD | 1 |
| Boeck, M; Klinker, E; Kobsar, A; Koessler, A; Koessler, J; Kuhn, S; Simonis, S | 1 |
| Banerjee, D; Mazumder, S; Sinha, AK | 1 |
| Dubey, BN; Fucile, G; Jenal, U; Lori, C; Ozaki, S; Plaza-Menacho, I; Schirmer, T | 1 |
| Boeck, M; Etzel, J; Kobsar, A; Koessler, A; Koessler, J; Schwarz, M; Weber, K | 1 |
| Dye, KJ; Yang, Z | 1 |
| Artemenko, EO; Filkova, AA; Gambaryan, SP; Maiorov, AS; Martyanov, AA; Panteleev, MA; Ryabykh, AA; Sveshnikova, AN; Svidelskaya, GS | 1 |
| Das, S; Günter, A; Jiao, K; Michalakis, S; Mühlfriedel, R; Paquet-Durand, F; Seeliger, MW; Yan, J | 1 |
| Costa, JL; Leonardi, GR; Lescano, CH; Mazetto, B; Monica, FZ; Orsi, FA | 1 |
2 review(s) available for adenosine diphosphate and cyclic gmp
| Article | Year |
|---|---|
Regulation of blood platelet function by cyclic nucleotides.
Topics: Adenosine Diphosphate; Blood Platelets; Cyclic AMP; Cyclic GMP; Deoxyadenosines; Humans; In Vitro Techniques; Prostaglandins E | 1978 |
Endothelium-dependent responses: the last three years.
Topics: Acetylcholine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcimycin; Cyclic GMP; Endothelium; Fatty Acids, Unsaturated; Hemoglobins; Methylene Blue; Norepinephrine; Vasodilation | 1984 |
2 trial(s) available for adenosine diphosphate and cyclic gmp
| Article | Year |
|---|---|
In central obesity, weight loss restores platelet sensitivity to nitric oxide and prostacyclin.
Topics: Adenosine Diphosphate; Adipose Tissue; Adult; Blood Platelets; Cyclic AMP; Cyclic GMP; Diet, Reducing; Endothelium, Vascular; Epoprostenol; Female; Humans; Iloprost; Insulin Resistance; Male; Nitric Oxide; Nitroprusside; Obesity, Abdominal; Platelet Activation; Platelet Aggregation Inhibitors; Weight Loss | 2010 |
Ramipril sensitizes platelets to nitric oxide: implications for therapy in high-risk patients.
Topics: Adenosine Diphosphate; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Arginine; Biomarkers; Blood Platelets; Cohort Studies; Cyclic GMP; Double-Blind Method; Drug Administration Schedule; Female; Guanylate Cyclase; Humans; Male; Malondialdehyde; Middle Aged; Nitric Oxide; Nitroprusside; Oxidative Stress; Platelet Aggregation; Ramipril; Thrombospondin 1 | 2012 |
159 other study(ies) available for adenosine diphosphate and cyclic gmp
| Article | Year |
|---|---|
Cytochalasin B, the blood platelet release reaction and cyclic GMP.
Topics: Adenosine Diphosphate; Blood Platelets; Carbon Radioisotopes; Collagen; Cyclic GMP; Cytochalasin B; Glucuronidase; Hexosaminidases; Humans; Kinetics; L-Lactate Dehydrogenase; Platelet Aggregation; Serotonin; Stimulation, Chemical; Tritium | 1975 |
The enhanced production of hyaluronic acid by cultured rat fibroblast cells treated with cyclic AMP and its dibutyryl derivative.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Bromodeoxyuridine; Bucladesine; Butyrates; Cell Count; Cell Division; Cell Line; Chondroitin Sulfates; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Glucuronates; Glucuronosyltransferase; Glycosaminoglycans; Heparitin Sulfate; Hyaluronic Acid; Prostaglandins E; Stimulation, Chemical; Theophylline | 1975 |
Platelet dysfunction in vincristine treated patients.
Topics: Adenosine Diphosphate; Blood Platelets; Child; Cyclic AMP; Cyclic GMP; Dimethyl Sulfoxide; Epinephrine; Humans; Leukemia, Lymphoid; Platelet Adhesiveness; Platelet Aggregation; Serotonin; Vincristine | 1976 |
Mitochondrial regulation in sea urchins. I. Mitochondrial ultrastructure transformations and changes in the ADP:ATP ratio at fertilization.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cyclic AMP; Cyclic GMP; Female; Mitochondria; Ovum; Oxygen Consumption; Sea Urchins; Zygote | 1976 |
The induction of filopodia in the cellular slime mold Dictyostelium discoideum by cyclic adenosine monophosphate: mechanism of aggregation.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Azides; Cell Aggregation; Concanavalin A; Cyclic AMP; Cyclic GMP; Dictyostelium; Dinitrophenols; Myxomycetes; Pseudopodia | 1976 |
Roles of cyclic nucleotides in platelet function.
Topics: Acetylcholine; Adenosine Diphosphate; Adenylyl Cyclases; Arginine Vasopressin; Aspirin; Blood Platelets; Calcium; Carbachol; Collagen; Cyclic AMP; Cyclic GMP; Epinephrine; Humans; In Vitro Techniques; Indomethacin; Papaverine; Platelet Aggregation; Prostaglandins E | 1975 |
Factors affecting platelet cyclic GMP levels during aggregation induced by collagen and by arachidonic acid.
Topics: Adenosine Diphosphate; Arachidonic Acids; Blood Platelets; Collagen; Cyclic GMP; Dose-Response Relationship, Drug; Guanosine Triphosphate; Humans; Indomethacin; Malondialdehyde; Platelet Aggregation; Serotonin | 1976 |
An improved protein binding assay for guanosine-3',5'-monophosphate using a binding protein from the pupa of the silkmoth, Bombyx mori L.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Bombyx; Cyclic AMP; Cyclic GMP; Protein Binding; Protein Kinases; Pupa | 1976 |
Human red cells protein kinase in normal subjects and patients with hereditary spherocytosis, sickle cell disease, and autoimmune hemolytic anemia.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Anemia, Hemolytic, Autoimmune; Anemia, Sickle Cell; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Erythrocyte Membrane; Guanosine Triphosphate; Humans; Kinetics; Phosphoproteins; Protein Kinases; Receptors, Drug; Spherocytosis, Hereditary; Time Factors | 1976 |
Inhibitors of hypoxanthine metabolism in Ehrlich ascites tumor cells in vitro.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Carcinoma, Ehrlich Tumor; Cyclic GMP; Energy Metabolism; Glutamine; Guanine Nucleotides; Guanosine Triphosphate; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; In Vitro Techniques; Inosine Nucleotides; Ketone Oxidoreductases; Ligases; Lyases; Mice; Purines | 1976 |
Self-phosphorylation of cyclic guanosine 3':5'-monophosphate-dependent protein kinase from bovine lung. Effect of cyclic adenosine 3':5'-monophosphate, cyclic guanosine 3':5'-monophosphate and histone.
Topics: Adenosine Diphosphate; Animals; Cattle; Cyclic AMP; Cyclic GMP; Enzyme Activation; Histones; Kinetics; Lung; Protein Kinases | 1977 |
Elevation of guanosine 3',5'-monophosphate level by adenosine in cerebellar slices of guinea pig.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Cerebellum; Cyclic AMP; Cyclic GMP; Guinea Pigs; In Vitro Techniques; Kinetics; Male; Papaverine; Phosphodiesterase Inhibitors; Theophylline; Xanthines | 1977 |
On the interrelationship of prostaglandin endoperoxide G2 and cyclic nucleotides in platelet function.
Topics: Adenosine Diphosphate; Blood Platelets; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Humans; Indomethacin; Models, Biological; Peroxides; Platelet Aggregation; Prostaglandins; Serotonin | 1977 |
Concentrations of energy metabolites and cyclic nucleotides during and after bilateral ischemia in the gerbil cerebral cortex.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Blood Glucose; Brain; Cyclic AMP; Cyclic GMP; Energy Metabolism; Gerbillinae; Glucose; Glycogen; Ischemia; Kinetics; Lactates; Phosphocreatine | 1977 |
Effect of exogenous nucleotides on the candicidin fermentation.
Topics: Adenine; Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Antifungal Agents; Candicidin; Cyclic AMP; Cyclic GMP; Fermentation; Guanine Nucleotides; Ribonucleosides; Streptomyces griseus; Uracil Nucleotides; Uridine Monophosphate | 1977 |
Platelet aggregation and cyclic nucleotide phosphodiesterase activity in arteriosclerotic patients.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine Diphosphate; Adult; Arteriosclerosis; Blood Platelets; Cyclic AMP; Cyclic GMP; Epinephrine; Female; Humans; Male; Middle Aged; Phosphoric Diester Hydrolases; Platelet Aggregation | 1978 |
Phospholipid-deacylating enzymes of rabbit platelets.
Topics: Adenosine Diphosphate; Animals; Anti-Inflammatory Agents; Blood Platelets; Calcium; Cyclic AMP; Cyclic GMP; Edetic Acid; Enzyme Activation; Epinephrine; Kinetics; Lysophospholipase; Phospholipases; Phospholipases A; Rabbits; Subcellular Fractions; Thrombin | 1979 |
Mode of action of dipyridamole on human platelets.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Adenosine Diphosphate; Adenylyl Cyclases; Blood Platelets; Cell Membrane; Cyclic AMP; Cyclic GMP; Dipyridamole; Epinephrine; Epoprostenol; Humans; Malondialdehyde; Platelet Aggregation; Thromboxane B2; Time Factors | 1979 |
Observations on the binding of adenosine 3':5'-monophosphate to cell membrane fragments from ox cerebral cortex.
Topics: Acetylcholine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Binding Sites; Binding, Competitive; Bucladesine; Cattle; Cell Membrane; Cerebral Cortex; Cyclic AMP; Cyclic GMP; Cyclic IMP; Hydrogen-Ion Concentration; Kinetics; Magnesium; Membranes; Microsomes; Protein Binding; Receptors, Drug; Synaptosomes | 1975 |
Cyclic 3',5'-nucleotide phosphodiesterase in rat skin. II. Biochemical characterization.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Bucladesine; Centrifugation, Density Gradient; Cyclic AMP; Cyclic GMP; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Epinephrine; Hydrocortisone; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Magnesium; Male; Manganese; Phosphoric Diester Hydrolases; Rats; Skin; Time Factors; Tritium | 1975 |
Role of cGMP and cGMP-dependent protein kinase in nitrovasodilator inhibition of agonist-evoked calcium elevation in human platelets.
Topics: Adenosine Diphosphate; Alprostadil; Blood Platelets; Calcium; Cell Compartmentation; Cyclic GMP; Cytoplasm; Humans; In Vitro Techniques; Ion Channel Gating; Kinetics; Molsidomine; Nitroprusside; Phosphoproteins; Protein Kinases; Receptors, Cell Surface; Thrombin; Vasodilator Agents | 1992 |
Cholera toxin augments the release of endothelium-derived relaxing factor evoked by bradykinin and the calcium ionophore A23187.
Topics: Adenosine Diphosphate; Animals; Bradykinin; Calcimycin; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Nitric Oxide; Swine | 1992 |
Cyclic nucleotide-dependent regulation of agonist-induced calcium increases in mouse megakaryocytes.
Topics: Adenosine Diphosphate; Animals; Bone Marrow; Calcium; Carrier Proteins; Cyclic AMP; Cyclic GMP; Dinoprostone; Drug Interactions; Enzyme Inhibitors; Intracellular Signaling Peptides and Proteins; Isoquinolines; Megakaryocytes; Mice; Protein Kinase Inhibitors | 1992 |
Determination of cyclic nucleotide-responsive protein kinase activity by quantitative fast atom bombardment mass spectrometry.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Cyclic AMP; Cyclic GMP; Cytidine Monophosphate; Kinetics; Protein Binding; Protein Kinases; Spectrometry, Mass, Fast Atom Bombardment | 1992 |
S-nitroso-glutathione inhibits platelet activation in vitro and in vivo.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Collagen; Cyclic AMP; Cyclic GMP; Glutathione; Humans; In Vitro Techniques; Indicators and Reagents; Male; Nerve Fibers; Nitric Oxide; Nitroso Compounds; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation; Rats; Rats, Wistar; S-Nitrosoglutathione | 1992 |
Increase in activating ability of human platelet guanylate cyclase during aggregation.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arginine; Blood Platelets; Cyclic GMP; Enzyme Activation; Guanylate Cyclase; Humans; Nitroprusside; Platelet Aggregation; Protoporphyrins | 1992 |
Inhibition by sodium nitroprusside or PGE1 of tyrosine phosphorylation induced in platelets by thrombin or ADP.
Topics: Adenosine Diphosphate; Alprostadil; Blood Platelets; Blotting, Western; Cyclic GMP; Cytosol; Electrophoresis, Polyacrylamide Gel; Humans; In Vitro Techniques; Kinetics; Nitroprusside; Phosphoproteins; Phosphorylation; Phosphotyrosine; Platelet Aggregation; Thrombin; Tyrosine | 1992 |
Developmental aspects of endothelial function.
Topics: Adenosine Diphosphate; Aging; Animals; Animals, Newborn; Calcimycin; Cerebral Arteries; Cerebrovascular Circulation; Cyclic GMP; Endothelium, Vascular; Fetus; Humans; Nitroglycerin; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Sheep; Vasoconstriction; Vasodilation | 1991 |
[Substantiation of possible determination of the effect of vibration on the functional responses of thrombocytes].
Topics: Adenosine Diphosphate; Adult; Culture Media; Cyclic AMP; Cyclic GMP; Humans; In Vitro Techniques; Middle Aged; Occupational Diseases; Occupational Medicine; Phosphoric Diester Hydrolases; Platelet Aggregation; Platelet Function Tests; Vibration | 1991 |
Regulation of the Ca2+ sensitivity of vascular smooth muscle contractile elements.
Topics: Actomyosin; Adenosine Diphosphate; Animals; Calcium; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Protein Kinases; Rabbits; Rats; Type C Phospholipases | 1991 |
Increase in reactivity of human platelet guanylate cyclase during aggregation potentiates the disaggregating capacity of sodium nitroprusside.
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Cyclic GMP; Guanylate Cyclase; Humans; Male; Middle Aged; Nitric Oxide; Nitroprusside; Platelet Aggregation; Platelet Aggregation Inhibitors | 1991 |
[The role of guanyl cyclase in the regulation of aggregation of human thrombocytes].
Topics: Adenosine Diphosphate; Blood Platelets; Culture Media; Cyclic GMP; Enzyme Activation; Guanylate Cyclase; Humans; In Vitro Techniques; Nitroprusside; Nitrous Oxide; Platelet Aggregation; Platelet Aggregation Inhibitors | 1991 |
Diphenylene iodonium, an inhibitor of free radical formation, inhibits platelet aggregation.
Topics: Adenosine Diphosphate; Biphenyl Compounds; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Free Radicals; Humans; Iloprost; In Vitro Techniques; Leukocytes; NADH, NADPH Oxidoreductases; Nitroprusside; Onium Compounds; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombin | 1991 |
Pertussis toxin inhibits cAMP-induced desensitization of adenylate cyclase in Dictyostelium discoideum.
Topics: Adenosine Diphosphate; Adenylate Cyclase Toxin; Adenylyl Cyclases; Cell Membrane; Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Down-Regulation; Enzyme Activation; Pertussis Toxin; Phosphorylation; Receptors, Cyclic AMP; Virulence Factors, Bordetella | 1990 |
Inhibition of fibrinogen binding to human platelets by S-nitroso-N-acetylcysteine.
Topics: Acetylcysteine; Adenosine Diphosphate; Blood Platelets; Cyclic GMP; Fibrinogen; Humans; In Vitro Techniques; Kinetics; Platelet Aggregation; Platelet Aggregation Inhibitors | 1990 |
Stimulation of cyclic GMP production in cultured endothelial cells of the pig by bradykinin, adenosine diphosphate, calcium ionophore A23187 and nitric oxide.
Topics: Adenosine Diphosphate; Animals; Arginine; Bradykinin; Calcimycin; Cells, Cultured; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Kinetics; Methylene Blue; Nitric Oxide; omega-N-Methylarginine; Oxyhemoglobins; Stimulation, Chemical; Superoxide Dismutase; Superoxides; Swine | 1990 |
Vasodilating agents and platelet function: intracellular free calcium concentration, cyclic nucleotides, and shape-change response.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Atrial Natriuretic Factor; Blood Platelets; Calcium; Cyclic AMP; Cyclic GMP; Humans; Pyridines; Quinazolines; Thrombin; Vasodilator Agents; Vasopressins | 1986 |
Nitroprusside differentially inhibits ADP-stimulated calcium influx and mobilization in human platelets.
Topics: Adenosine Diphosphate; Binding Sites; Blood Platelets; Calcium; Cyclic GMP; Ethers; Female; Ferricyanides; Humans; Ionomycin; Ionophores; Male; Nitroprusside; Tetradecanoylphorbol Acetate | 1989 |
Endothelium-dependent dilation of feline cerebral arteries: role of membrane potential and cyclic nucleotides.
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Aorta; Cats; Cerebral Arteries; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Male; Membrane Potentials; Ouabain; Pressure; Serotonin; Vasodilation | 1989 |
Cyclic GMP, cyclic AMP, glucose at birth, and maturation of rat liver mitochondria.
Topics: Adenosine Diphosphate; Animals; Animals, Newborn; Bucladesine; Cyclic AMP; Cyclic GMP; Glucose; Kinetics; Liver; Mitochondria, Liver; Nitroprusside; Oxidation-Reduction; Pentoxifylline; Rats; Rats, Inbred Strains | 1988 |
Inhibition of platelet aggregation by carbon monoxide is mediated by activation of guanylate cyclase.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Carbon Monoxide; Cyclic GMP; Enzyme Activation; Epinephrine; Epoprostenol; Guanylate Cyclase; Humans; In Vitro Techniques; Nitroprusside; Phospholipids; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Thromboxane B2 | 1987 |
Mechanism of the inhibition of platelet aggregation produced by prostaglandin F2 alpha.
Topics: Adenosine Diphosphate; Aspirin; Cyclic AMP; Cyclic GMP; Dinoprost; Humans; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins F; Prostaglandins H; Prostaglandins, Synthetic; Thrombin | 1985 |
Benzodiazepines inhibit human platelet activation: comparison of the mechanism of antiplatelet actions of flurazepam and diazepam.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Benzodiazepinones; Blood Platelets; Collagen; Cyclic AMP; Cyclic GMP; Diazepam; Epinephrine; Flumazenil; Flurazepam; Humans; Malondialdehyde; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Serotonin; Thrombin; Type C Phospholipases | 1985 |
Identification and partial purification of a nucleotide-stimulated protease in rat retina.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Chromatography, DEAE-Cellulose; Cyclic GMP; Enzyme Activation; Peptide Hydrolases; Rats; Rats, Inbred Strains; Retina | 1985 |
Influence of beta 2-glycoprotein-I upon the content of cAMP and cGMP in human blood platelets.
Topics: Adenosine Diphosphate; beta 2-Glycoprotein I; Blood Platelets; Cyclic AMP; Cyclic GMP; Glycoproteins; Humans; In Vitro Techniques; Platelet Aggregation | 1985 |
Mechanism of action of the platelet function inhibitor from Vipera russelli siamensis snake venom.
Topics: Adenosine Diphosphate; Blood Platelets; Cyclic AMP; Cyclic GMP; Humans; In Vitro Techniques; Malondialdehyde; Phospholipases A; Phospholipases A2; Platelet Aggregation; Thrombin; Viper Venoms | 1986 |
Regulation of lens cyclic nucleotide metabolism by Ca2+ plus calmodulin.
Topics: Adenosine Diphosphate; Adenylyl Cyclases; Animals; Calcium; Calmodulin; Cattle; Cell Membrane; Cholera Toxin; Cyclic AMP; Cyclic GMP; Egtazic Acid; Enzyme Activation; Lens, Crystalline | 1987 |
Proceedings: Cyclic GMP formation in human platelets.
Topics: Adenosine Diphosphate; Blood Platelets; Calcium; Chromatography; Cyclic AMP; Cyclic GMP; Dithiothreitol; Dose-Response Relationship, Drug; Edetic Acid; Epinephrine; Guanylate Cyclase; Humans; In Vitro Techniques; Isoproterenol; Norepinephrine; Serotonin; Time Factors | 1974 |
Cyclic nucleotide phosphodiesterase activity in man, monkey, and rat.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adult; Animals; Brain; Chlorpromazine; Cyclic AMP; Cyclic GMP; Cytosine Nucleotides; Guanine Nucleotides; Haplorhini; Histamine; Humans; Hydrolysis; Imidazoles; Male; Middle Aged; Muscles; Myocardium; Norepinephrine; Nucleosides; Pancreas; Phosphoric Monoester Hydrolases; Rats; Reserpine; Serotonin; Spleen; Triiodothyronine; Uracil Nucleotides | 1971 |
Morphological and biochemical study in x-ray- and dibutyryl cyclic AMP-induced differentiated neuroblastoma cells.
Topics: Acetylcholinesterase; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Axons; Butyrates; Cell Differentiation; Cell Division; Cell Survival; Cells, Cultured; Cholinesterases; Culture Media; Cyclic AMP; Cyclic GMP; DNA, Neoplasm; Mice; Neuroblastoma; Radiation Effects; Time Factors | 1972 |
Cyclic AMP-stimulated protein kinase prepared from bovine thyroid glands.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Caseins; Cattle; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Cobalt; Cyclic AMP; Cyclic GMP; Cytosine Nucleotides; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Guanine Nucleotides; Guanosine; Histones; Hydrogen-Ion Concentration; In Vitro Techniques; Isoleucine; Magnesium; Manganese; Nucleotides; Phosphorus Isotopes; Phosphotransferases; Protamines; Proteins; Serum Albumin, Bovine; Thyroid Gland; Uracil Nucleotides | 1972 |
Association of poly ADP-ribose glycohydrolase with liver chromatin.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Ammonium Sulfate; Animals; Carbon Isotopes; Cell Nucleus; Chromatin; Chromatography, Ion Exchange; Cyclic AMP; Cyclic GMP; Glycoside Hydrolases; Hydrogen-Ion Concentration; Liver; Niacinamide; Polynucleotides; Rats; Ribose; Sodium Chloride; Thymidine | 1972 |
A nucleoside diphosphate phosphohydrolase present in a coated-vesicle fraction from synaptosomes of guinea-pig whole brain.
Topics: Adenosine Diphosphate; Animals; Brain; Cyclic GMP; Cytidine; Cytosine Nucleotides; Guinea Pigs; Inosine Nucleotides; Phosphoric Monoester Hydrolases; Synaptic Vesicles; Synaptosomes; Thiamine Pyrophosphate | 1973 |
A new enzymatic assay for guanosine 3':5'-cyclic monophosphate and its application to the ductus deferens of the rat.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Carbachol; Cyclic AMP; Cyclic GMP; Guanine Nucleotides; Male; Methods; Myosins; Norepinephrine; Phosphoric Diester Hydrolases; Phosphorus Isotopes; Phosphotransferases; Rats; Vas Deferens | 1973 |
Promotion of conidia aggregation in Aspergillus niger by cyclic AMP and 5'-GMP.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aspergillus; Bucladesine; Cell Aggregation; Cell Division; Cyclic AMP; Cyclic GMP; Guanine Nucleotides; Guanosine; Theophylline | 1973 |
Induction of delta-aminolevulinic acid synthetase in isolated rat liver cell suspensions. Adenosine 3':5'-monophosphate dependence of induction by drugs.
Topics: 5-Aminolevulinate Synthetase; Acetamides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Allylisopropylacetamide; Animals; Bucladesine; Cyclic AMP; Cyclic GMP; Cycloheximide; Dactinomycin; Dicarboxylic Acids; Drug Synergism; Enzyme Induction; Fasting; Hydrocortisone; In Vitro Techniques; Kinetics; Liver; Male; Pyridines; Rats; RNA; Time Factors | 1974 |
The effects of nucleotides on the alpha-glucosidase formation in baker's yeast protoplasts.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Culture Media; Cyclic AMP; Cyclic GMP; Glucosidases; Magnesium; Manganese; Protoplasts; Saccharomyces cerevisiae; Stimulation, Chemical; Uracil Nucleotides | 1973 |
The protective effects of nucleotides on the histamine hypersensitivity of Bordetella pertussis-treated mice.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Anaphylaxis; Animals; Bordetella pertussis; Bucladesine; Corticosterone; Cyclic AMP; Cyclic GMP; Deoxyribonucleotides; Female; Histamine; Hypersensitivity, Immediate; Hypoglycemia; Inosine Nucleotides; Mice; Nucleotides; Prostaglandins; Spleen; Thymine Nucleotides; Thymus Gland; Time Factors | 1974 |
Effect of pharmacological agents on human keratinocyte mitosis in vitro. I. Inhibition by adenine nucleotides.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Bucladesine; Cells, Cultured; Cyclic AMP; Cyclic GMP; Cytidine; Cytosine Nucleotides; Depression, Chemical; Guanine; Guanine Nucleotides; Guanosine; Guanosine Triphosphate; Humans; Hypoxanthines; Inosine; Inosine Nucleotides; Mitosis; Skin; Thymine Nucleotides; Uracil Nucleotides | 1974 |
A rapid and simple procedure for the determination of guanosine 3',5'-monophosphate by use of the protein-binding method.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Brain; Brain Chemistry; Charcoal; Cyclic AMP; Cyclic GMP; Depression, Chemical; Guanosine Triphosphate; Hydrogen-Ion Concentration; Magnesium; Male; Methods; Muscles; Nephropidae; Protein Binding; Rats; Tritium | 1974 |
Studies on cyclic AMP phosphodiesterase in sea urchin eggs.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Ammonium Sulfate; Animals; Antimetabolites; Bucladesine; Butyrates; Chromatography, Thin Layer; Cyclic AMP; Cyclic GMP; Female; Fertilization; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Magnesium; Mathematics; Ovum; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Sea Urchins; Subcellular Fractions; Time Factors; Tritium | 1974 |
Post-ischaemic synchronous purine nucleotide oscillations in perfused rat heart.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Coronary Disease; Cyclic AMP; Cyclic GMP; Epinephrine; Guanosine Diphosphate; Guanosine Triphosphate; Heart; Inosine Monophosphate; Kinetics; Male; Myocardium; Perfusion; Purine Nucleotides; Rats; Rats, Inbred Strains | 1984 |
Biochemical and ultrastructural studies of human eccrine sweat glands isolated by shearing and maintained for seven days.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adolescent; Adult; Cyclic AMP; Cyclic GMP; Dissection; Eccrine Glands; Humans; Male; Microscopy, Electron; Proteins; Sweat Glands | 1984 |
The distribution of the components of the cyclic GMP cycle in retina.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cyclic GMP; Cytidine Triphosphate; Darkness; Guanosine Diphosphate; Guanosine Triphosphate; Guanylate Cyclase; Haplorhini; Light; Macaca fascicularis; Nucleoside-Diphosphate Kinase; Rabbits; Retina; Sciuridae; Species Specificity; Uridine Triphosphate | 1980 |
Evidence for the inhibitory role of guanosine 3', 5'-monophosphate in ADP-induced human platelet aggregation in the presence of nitric oxide and related vasodilators.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Cattle; Cyclic GMP; Guanylate Cyclase; Humans; Methylnitronitrosoguanidine; Nitric Oxide; Nitroprusside; Platelet Aggregation; Smoking; Vasodilator Agents | 1981 |
On the relationship between aggregation and cyclic nucleotides in platelets treated with betaadrenoceptor blocking drugs.
Topics: Adenosine Diphosphate; Adrenergic beta-Antagonists; Animals; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Male; Platelet Aggregation; Rats; Rats, Inbred Strains | 1983 |
Mepacrine-induced elevation of cyclic GMP levels and acceleration of reversal of ADP-induced aggregation in washed rabbit platelets.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Diphosphate; Animals; Ascorbic Acid; Blood Platelets; Cyclic GMP; Guanylate Cyclase; Kinetics; Nitroprusside; Platelet Aggregation; Quinacrine; Rabbits | 1983 |
Cyclic GMP binding and phosphodiesterase: implication for platelet function.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Adenosine Diphosphate; Blood Platelets; Carrier Proteins; Cyclic GMP; Dipyridamole; Humans; Intracellular Signaling Peptides and Proteins; Nitroprusside; Platelet Aggregation; Receptors, Cyclic AMP | 1984 |
Effect of ascorbate on abnormal neutrophil, platelet and lymphocytic function in a patient with the Chediak-Higashi syndrome.
Topics: Adenosine Diphosphate; Adolescent; Ascorbic Acid; Bleeding Time; Blood Platelets; Cell Movement; Chediak-Higashi Syndrome; Chemotaxis, Leukocyte; Cyclic AMP; Cyclic GMP; Humans; Hypersensitivity, Delayed; Lymphocytes; Male; Neutrophils; Nucleotides, Cyclic; Peroxidase | 1981 |
Inhibition of platelet aggregation by 6-keto-PGE1; lack of an effect on cyclic GMP levels.
Topics: Adenosine Diphosphate; Alprostadil; Arachidonic Acids; Blood Platelets; Collagen; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Female; Humans; Platelet Aggregation; Prostaglandins E | 1981 |
Role of purines in acetylcholine-induced coronary vasodilation.
Topics: Acetylcholine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Coronary Vessels; Cyclic AMP; Cyclic GMP; Guinea Pigs; Heart; In Vitro Techniques; Receptors, Muscarinic; Vasodilation | 1982 |
Organic nitrates and compounds that increase intraplatelet cyclic guanosine monophosphate (cGMP) levels enhance the antiaggregating effects of the stable prostacyclin analogue iloprost.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Diphosphate; Adult; Arginine; Blood Platelets; Collagen; Cyclic AMP; Cyclic GMP; Drug Synergism; Endothelium, Vascular; Epinephrine; Humans; Iloprost; Intracellular Fluid; Male; Nitroglycerin; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Factor 4; Second Messenger Systems | 1993 |
Antiplatelet effects of a novel antianginal agent, nicorandil.
Topics: Acetylcysteine; Adenosine Diphosphate; Analysis of Variance; Binding Sites; Blood Platelets; Cyclic GMP; Dose-Response Relationship, Drug; Drug Tolerance; Fibrinogen; Guanylate Cyclase; Humans; Niacinamide; Nicorandil; Platelet Aggregation; Platelet Aggregation Inhibitors; Potassium Channels; Radioimmunoassay; Vasodilator Agents | 1994 |
Insulin increases guanosine-3',5'-cyclic monophosphate in human platelets. A mechanism involved in the insulin anti-aggregating effect.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Diphosphate; Adult; Amino Acid Oxidoreductases; Arginine; Blood Platelets; Collagen; Cyclic GMP; Female; Genistein; Guanylate Cyclase; Humans; Insulin; Isoflavones; Male; Methylene Blue; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein-Tyrosine Kinases; Radioimmunoassay; Recombinant Proteins | 1994 |
Aldose reductase inhibition restores endothelial cell function in diabetic rabbit aorta.
Topics: Acetylcholine; Adenosine Diphosphate; Aldehyde Reductase; Animals; Aorta; Blood Glucose; Body Weight; Cyclic GMP; Diabetes Mellitus, Experimental; Endothelium, Vascular; Imidazoles; Imidazolidines; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine; Prostaglandins; Rabbits; Sorbitol | 1993 |
Antiplatelet effects of nitroglycerin in healthy subjects and in patients with stable angina pectoris.
Topics: Adenosine Diphosphate; Adult; Aged; Angina Pectoris; Blood Platelets; Cyclic GMP; Female; Humans; In Vitro Techniques; Male; Middle Aged; Nitroglycerin; Platelet Aggregation Inhibitors | 1993 |
[NO. and the central nervous system].
Topics: Adenosine Diphosphate; Alzheimer Disease; Brain Chemistry; Cell Communication; Cyclic GMP; Humans; Huntington Disease; Neurotransmitter Agents; Nitric Oxide | 1995 |
Endogenous ADP-ribosylation of glyceraldehyde-3-phosphate dehydrogenase that is not regulated by nitric oxide in Dictyostelium discoideum.
Topics: Adenosine Diphosphate; Animals; Cyclic GMP; Cytosol; Dictyostelium; Genetic Linkage; Glyceraldehyde-3-Phosphate Dehydrogenases; Guanylate Cyclase; Nitric Oxide; Peptide Fragments; Peptide Mapping | 1993 |
[Soluble platelet guanylate cyclase: significance of heme in regulating enzymatic activity and the role of the enzyme in platelet aggregation].
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Cyclic GMP; Enzyme Activation; Guanylate Cyclase; Heme; Humans; In Vitro Techniques; Oxidation-Reduction; Platelet Aggregation; Rats; Solubility | 1994 |
L-arginine attenuates platelet reactivity in hypercholesterolemic rabbits.
Topics: Adenosine Diphosphate; Animals; Arginine; Blood Platelets; Calcium; Cholesterol; Cholesterol, Dietary; Cyclic GMP; Hypercholesterolemia; Intracellular Membranes; Male; Platelet Aggregation; Rabbits | 1994 |
Escherichia coli endotoxin inhibits agonist-mediated cytosolic Ca2+ mobilization and nitric oxide biosynthesis in cultured endothelial cells.
Topics: Adenosine Diphosphate; Animals; Bradykinin; Calcium; Cattle; Cells, Cultured; Cyclic GMP; Cytosol; Endothelium, Vascular; Endotoxins; Escherichia coli; Lipopolysaccharides; Luminescent Measurements; Nitric Oxide; Swine | 1994 |
Inhibition of ADP-induced human platelet aggregation by a new class of soluble guanylate cyclase activators capable of nitric oxide generation.
Topics: Adenosine Diphosphate; Azetidines; Blood Platelets; Cyclic GMP; Enzyme Activation; Guanylate Cyclase; Humans; Nitric Oxide; Platelet Aggregation; Platelet Aggregation Inhibitors; Solubility | 1994 |
Spontaneous nitric oxide release accounts for the potent pharmacological actions of FK409.
Topics: Adenosine Diphosphate; Administration, Oral; Animals; Aorta; Blood Pressure; Cyclic GMP; Drug Stability; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitro Compounds; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 1994 |
Effects of L- and D-arginine and some related esters on the cytosolic mechanisms of alpha-thrombin-induced human platelet activation.
Topics: Adenosine Diphosphate; Apyrase; Arachidonic Acids; Arginine; Blood Platelets; Cyclic GMP; Cytosol; Humans; In Vitro Techniques; Indomethacin; Kinetics; Nitroprusside; Platelet Activation; Platelet Aggregation Inhibitors; Sodium-Hydrogen Exchangers; Spectrometry, Fluorescence; Stereoisomerism; Thrombin | 1993 |
[The mechanism of the inhibiting effect of a Yersinia pestis protein factor on the hormone-stimulated response of human thrombocytes].
Topics: Adenosine Diphosphate; Bacterial Proteins; Bacterial Toxins; Blood Platelets; Calcium; Cyclic AMP; Cyclic GMP; Depression, Chemical; Humans; Platelet Activation; Stimulation, Chemical; Yersinia pestis | 1993 |
Adverse vascular effects of homocysteine are modulated by endothelium-derived relaxing factor and related oxides of nitrogen.
Topics: Adenosine Diphosphate; Animals; Aorta; Blood Platelets; Cattle; Cells, Cultured; Collagen; Copper; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Homocysteine; Homocystine; Humans; Hydrogen Peroxide; In Vitro Techniques; Iron; Kinetics; Luminescent Measurements; Magnetic Resonance Spectroscopy; Models, Cardiovascular; Nitric Oxide; Nitrogen Oxides; Platelet Aggregation; Platelet Aggregation Inhibitors | 1993 |
Antiplatelet properties of protein S-nitrosothiols derived from nitric oxide and endothelium-derived relaxing factor.
Topics: Adenosine Diphosphate; Animals; Bleeding Time; Blood Coagulation; Blood Platelets; Blood Proteins; Collagen; Cyclic GMP; Cysteine; Dogs; Fibrinogen; Glutathione; Humans; Molecular Weight; Nitric Oxide; Nitroso Compounds; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Binding; S-Nitrosoglutathione; S-Nitrosothiols; Time Factors | 1993 |
Influence of the cGMP analog 8-PCPT-cGMP on agonist-induced increases in cytosolic ionized Ca2+ and on aggregation of human platelets.
Topics: Adenosine Diphosphate; Blood Platelets; Calcium; Collagen; Cyclic GMP; Cytosol; Female; Humans; Male; Platelet Aggregation; Thionucleotides; Thrombin | 1993 |
Salivary gland extracts from the deerfly contain a potent inhibitor of platelet aggregation.
Topics: Adenosine Diphosphate; Animals; Apyrase; Blood Platelets; Cell Separation; Cyclic AMP; Cyclic GMP; Diptera; Electrophoresis, Polyacrylamide Gel; Fibrinogen; Humans; Kinetics; Molecular Weight; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Salivary Glands; Salivary Proteins and Peptides; Tissue Extracts | 1993 |
Insulin exerts opposite effects on platelet function at physiological and supraphysiological concentrations.
Topics: Adenosine Diphosphate; Adult; Cyclic GMP; Dose-Response Relationship, Drug; Female; Humans; Insulin; Male; Nitroglycerin; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinones; Theophylline; Vasodilator Agents | 1996 |
Antithrombotic effects of peroxynitrite: inhibition and reversal of aggregation in human platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adult; Blood Platelets; Collagen; Cyclic GMP; Humans; Nitrates; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Spectrophotometry; Thrombin; Thromboxane A2 | 1995 |
Intracellular levels of cyclic AMP and cyclic GMP differentially modify platelet aggregate size in human platelets activated with epinephrine or ADP.
Topics: Adenosine Diphosphate; Adrenergic alpha-Agonists; Blood Platelets; Bucladesine; Cyclic AMP; Cyclic GMP; Epinephrine; Epoprostenol; Humans; In Vitro Techniques; Light; Milrinone; Nitroprusside; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Pyridones; Scattering, Radiation | 1996 |
Nitric oxide released from activated platelets inhibits platelet recruitment.
Topics: Adenosine Diphosphate; Adult; Biotin; Blood Platelets; Cyclic GMP; Cytoplasmic Granules; Flow Cytometry; Humans; Microelectrodes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; P-Selectin; Platelet Activation; Platelet Aggregation; Serotonin; Thrombosis | 1997 |
Purification of bovine soluble guanylate cyclase and ADP-ribosylation on its small subunit by bacterial toxins.
Topics: Adenosine Diphosphate; Adenosine Diphosphate Ribose; Animals; Bacterial Toxins; Cattle; Cyclic GMP; Guanosine Triphosphate; Guanylate Cyclase; Heme; Kinetics; Lung; Macromolecular Substances; Manganese; NAD; Nitric Oxide; Sensitivity and Specificity; Solubility | 1997 |
The regulation of platelet aggregation in vitro by interleukin-1beta and tumor necrosis factor-alpha: changes in pregnancy and in pre-eclampsia.
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Cyclic AMP; Cyclic GMP; Female; Humans; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Middle Aged; Nitric Oxide; P-Selectin; Platelet Aggregation; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Recombinant Proteins; Second Messenger Systems; Sialoglycoproteins; Thromboxane B2; Tumor Necrosis Factor-alpha | 1997 |
Comparative effects of continuous warm blood and intermittent cold blood cardioplegia on coronary reactivity.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Diphosphate; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Blood; Calcimycin; Colforsin; Coronary Vessels; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Endothelium, Vascular; Enzyme Activation; Guanidines; Heart Arrest, Induced; In Vitro Techniques; Isoproterenol; Microcirculation; Pinacidil; Potassium Channels; Swine; Temperature; Vasodilation; Vasodilator Agents | 1997 |
Modulation of glutamate release from rat hippocampal synaptosomes by nitric oxide.
Topics: 4-Aminopyridine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cyclic GMP; Glutamic Acid; Hippocampus; Hydroxylamine; Male; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Synaptosomes | 1997 |
Platelet resistance to nitrates in obesity and obese NIDDM, and normal platelet sensitivity to both insulin and nitrates in lean NIDDM.
Topics: Adenosine Diphosphate; Adult; Analysis of Variance; Blood Glucose; Blood Platelets; Blood Pressure; Body Mass Index; Cholesterol; Cholesterol, HDL; Cyclic GMP; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; Insulin; Insulin Resistance; Male; Nitroglycerin; Obesity; Platelet Aggregation; Platelet Aggregation Inhibitors; Reference Values; Thinness; Triglycerides | 1998 |
Increased aggregation of human platelets produced by advanced glycation end products in vitro.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Arginine; Arteriosclerosis; Cyclic AMP; Cyclic GMP; Female; Glycation End Products, Advanced; Humans; Indomethacin; Lysine; Male; Oxidative Stress; Platelet Aggregation; Polylysine; Prostaglandins; Reactive Oxygen Species; Serum Albumin, Bovine; Superoxide Dismutase; Superoxides | 1998 |
Selective stimulation of L-arginine uptake contributes to shear stress-induced formation of nitric oxide.
Topics: Adenosine Diphosphate; Animals; Aorta; Arginine; Biological Transport; Bradykinin; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Kinetics; Leucine; Nitric Oxide; Stress, Mechanical; Superoxide Dismutase; Swine; Thapsigargin | 1999 |
Modulation of human platelet function by L-canavanine: differential effects of low and high concentrations.
Topics: Adenosine Diphosphate; Arginine; Blood Platelets; Canavanine; Catecholamines; Cyclic GMP; Drug Interactions; Humans; In Vitro Techniques; Nitric Oxide Synthase; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Serotonin | 1999 |
Endothelial regulation of vascular contraction in radial and internal mammary arteries.
Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Adenosine Diphosphate; Cyclic GMP; Dinoprost; Endothelium, Vascular; Gene Transfer Techniques; Humans; Ionophores; Mammary Arteries; Muscle, Smooth, Vascular; Nitric Oxide; Organ Culture Techniques; Radial Artery; Thrombin; Vasoconstriction; Vasodilator Agents | 1999 |
Antiplatelet mechanisms of TA-993 and its metabolite MB3 in ADP-induced platelet aggregation.
Topics: Actins; Adenosine Diphosphate; Blood Platelets; Calcium; Cyclic AMP; Cyclic GMP; Diltiazem; Dose-Response Relationship, Drug; Fibrinogen; Fura-2; Humans; Male; Oligopeptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Binding | 2000 |
Effect of Jindangwon on streptozotocin-induced diabetes.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cyclic GMP; Diabetes Mellitus, Experimental; Enzymes; Glucose Transporter Type 2; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Monosaccharide Transport Proteins; Streptozocin | 2000 |
cGMP-dependent ADP depolymerization of actin mediates estrogen increase in cervical epithelial permeability.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Actins; Adenosine Diphosphate; Alkaloids; Aminoquinolines; Carbazoles; Cell Membrane Permeability; Cells, Cultured; Cervix Mucus; Cervix Uteri; Cyclic GMP; Enzyme Inhibitors; Epithelial Cells; Estradiol; Estrogen Antagonists; Female; Humans; In Vitro Techniques; Indoles; Nitric Oxide; Nitroprusside; Polymers; Ribose; Tamoxifen; Vasodilator Agents | 2000 |
Inhibition of human platelet aggregation by nitric oxide donor drugs: relative contribution of cGMP-independent mechanisms.
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Collagen; Cyclic GMP; Enzyme Inhibitors; Glucosamine; Glutathione; Humans; In Vitro Techniques; Kinetics; Models, Biological; Nitric Oxide Donors; Nitroglycerin; Nitroprusside; Nitroso Compounds; Oxadiazoles; Penicillamine; Platelet Aggregation; Platelet Aggregation Inhibitors; Quaternary Ammonium Compounds; Quinoxalines; S-Nitrosoglutathione | 2000 |
Parathyroid hormone potentiates nucleotide-induced [Ca2+]i release in rat osteoblasts independently of Gq activation or cyclic monophosphate accumulation. A mechanism for localizing systemic responses in bone.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Diphosphate; Animals; Calcium; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic GMP; Gene Expression; GTP-Binding Protein alpha Subunits, Gq-G11; Heterotrimeric GTP-Binding Proteins; Osteoblasts; Parathyroid Hormone; Phosphorylation; Promoter Regions, Genetic; Proto-Oncogene Proteins c-fos; Purinergic P2 Receptor Agonists; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y1 | 2001 |
Cyclic nucleotides modulate store-mediated calcium entry through the activation of protein-tyrosine phosphatases and altered actin polymerization in human platelets.
Topics: Actins; Adenosine Diphosphate; Alprostadil; Arsenicals; Blood Platelets; Calcium; Carbazoles; Cyclic AMP; Cyclic GMP; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Humans; In Vitro Techniques; Indoles; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nitroprusside; Phosphorylation; Platelet Activation; Platelet Aggregation Inhibitors; Protein Tyrosine Phosphatases; Pyrroles; Thapsigargin; Thrombin; Vanadates | 2001 |
Studies on inhibition of human platelet function by sodium nitroprusside. Kinetic evaluation of the effect on aggregation and cyclic nucleotide content.
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Kinetics; Male; Nitroprusside; Platelet Aggregation; Platelet Aggregation Inhibitors; Time Factors | 2001 |
N-acetyl-L-cysteine exerts direct anti-aggregating effect on human platelets.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Acetylcysteine; Adenosine Diphosphate; Adult; Calcimycin; Cell Membrane Permeability; Collagen; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Humans; Ionomycin; Male; omega-N-Methylarginine; Oxadiazoles; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinones; Quinoxalines | 2001 |
Downregulation of vascular soluble guanylate cyclase induced by high salt intake in spontaneously hypertensive rats.
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Aorta, Thoracic; Blood Pressure; Calcimycin; Cyclic GMP; Dose-Response Relationship, Drug; Down-Regulation; Endothelium, Vascular; Guanylate Cyclase; Heart Rate; Hypertension; In Vitro Techniques; Ionophores; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroglycerin; Nitroprusside; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium Chloride, Dietary; Solubility; Species Specificity; Vasodilation; Vasodilator Agents | 2001 |
Effects of the reactive oxygen species hydrogen peroxide and hypochlorite on endothelial nitric oxide production.
Topics: Adenosine Diphosphate; Animals; Arginine; Bradykinin; Calcimycin; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Hydrogen Peroxide; Hypochlorous Acid; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroprusside; omega-N-Methylarginine; Oxidants; Swine | 2001 |
Inhibition of platelet-collagen interaction: an in vivo action of insulin abolished by insulin resistance in obesity.
Topics: Adenosine Diphosphate; Adult; Analysis of Variance; Blood Platelets; Body Mass Index; Collagen; Cyclic GMP; Enzyme-Linked Immunosorbent Assay; Epinephrine; Glucose; Glucose Clamp Technique; Hemostasis; Humans; Insulin; Insulin Resistance; Obesity; Peptide Fragments; Platelet Aggregation | 2002 |
Adenosine increases human platelet levels of cGMP through nitric oxide: possible role in its antiaggregating effect.
Topics: Adenosine; Adenosine Diphosphate; Blood Platelets; Cyclic GMP; Dose-Response Relationship, Drug; Drug Antagonism; Guanylate Cyclase; Humans; Nitric Oxide; Platelet Aggregation; Platelet Aggregation Inhibitors | 2002 |
P2Y(1) and P2Y(2) receptors are coupled to the NO/cGMP pathway to vasodilate the rat arterial mesenteric bed.
Topics: Adenosine Diphosphate; Animals; Cyclic GMP; Endothelium, Vascular; Guanylate Cyclase; Humans; Luminescent Measurements; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nucleotides; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Soluble Guanylyl Cyclase; Vasodilation | 2002 |
Inhibition of rat platelet aggregation by the diazeniumdiolate nitric oxide donor MAHMA NONOate.
Topics: Adenosine Diphosphate; Animals; Catalase; Collagen; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activators; Enzyme Inhibitors; Guanylate Cyclase; Hydrazines; In Vitro Techniques; Indazoles; Male; Nitric Oxide Donors; Oxadiazoles; Platelet Aggregation; Platelet Aggregation Inhibitors; Pulmonary Artery; Quinoxalines; Rats; Rats, Wistar; S-Nitrosoglutathione; Superoxide Dismutase; Thapsigargin; Thionucleotides; Vasoconstriction | 2002 |
Implication of guanosine 3',5'-cyclic monophosphate, adenosine 3',5'-cyclic monophosphate, adenosine 5'-mono-, di- and triphosphate and fructose-2,6-bisphosphate in the regulation of the glycolytic pathway in hypoxic/anoxic mussel, Mytilus galloprovincial
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Bivalvia; Cyclic AMP; Cyclic GMP; Fructosediphosphates; Glycolysis; Hypoxia; Phosphates | 2002 |
Comparison between the effects of the rapid recombinant insulin analog Lispro (Lys B28, Pro B29) and those of human regular insulin on platelet cyclic nucleotides and aggregation.
Topics: Adenosine Diphosphate; Adult; Androstadienes; Blood Platelets; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Insulin; Insulin Lispro; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phosphoinositide-3 Kinase Inhibitors; Platelet Aggregation; Recombinant Proteins; Wortmannin | 2003 |
Platelet resistance to the antiaggregating effect of N-acetyl-L-cysteine in obese, insulin-resistant subjects.
Topics: Acetylcysteine; Adenosine Diphosphate; Adult; Amifostine; Antioxidants; Collagen; Cyclic GMP; Drug Resistance; Female; Free Radical Scavengers; Humans; Insulin Resistance; Male; Nitric Oxide; Nitric Oxide Donors; Nitroglycerin; Nitroprusside; Obesity; Platelet Aggregation; Platelet Aggregation Inhibitors; Superoxide Dismutase | 2003 |
Role of ascorbic acid in the modulation of inhibition of platelet aggregation by polymorphonuclear leukocytes.
Topics: Adenosine Diphosphate; Adult; Animals; Ascorbic Acid; Blood Platelets; Cyclic GMP; Dehydroascorbic Acid; Humans; Macaca mulatta; Male; Neutrophils; Nitric Oxide; Platelet Aggregation; Rats; Rats, Sprague-Dawley | 2003 |
Activation of purinergic receptor subtypes modulates odor sensitivity.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Male; Membrane Potentials; Mice; Olfactory Mucosa; Olfactory Receptor Neurons; Patch-Clamp Techniques; Pyridoxal Phosphate; Rats; Rats, Inbred Strains; Receptors, Purinergic; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Receptors, Purinergic P2Y2; RNA, Messenger; Sensory Thresholds; Smell; Stimulation, Chemical; Thionucleotides | 2003 |
Antiplatelet properties of a novel, non-NO-based soluble guanylate cyclase activator, BAY 41-2272.
Topics: Adenosine Diphosphate; Animals; Antihypertensive Agents; Blood Pressure; Carotid Artery Thrombosis; Chlorides; Cyclic GMP; Enzyme Activators; Epoprostenol; Ferric Compounds; Guanylate Cyclase; In Vitro Techniques; Male; Nitric Oxide; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrazoles; Pyridines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Time Factors | 2003 |
Implication of adenosine 3',5'-cyclic monophosphate, guanosine 3',5'-cyclic monophosphate, adenosine 5'-mono-, di-, and triphosphate and fructose-2,6-bisphosphate in the regulation of the glycolytic pathway in relation to the gametogenic cycle in the muss
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Bivalvia; Cyclic AMP; Cyclic GMP; Enzyme Activation; Fructosediphosphates; Germ Cells; Phosphofructokinase-1 | 2003 |
H2O2-induced platelet aggregation and increase in intracellular Ca2+ concentration are blocked by inhibitors of intracellular signaling.
Topics: Adenosine Diphosphate; Arachidonic Acid; Blood Platelets; Calcium; Calcium Signaling; Cyclic AMP; Cyclic GMP; Humans; Hydrogen Peroxide; Platelet Aggregation; Platelet Aggregation Inhibitors | 2003 |
Anticonvulsant effect of GMP depends on its conversion to guanosine.
Topics: Adenosine Diphosphate; Animals; Anticonvulsants; Cyclic GMP; Dose-Response Relationship, Drug; Guanosine; Male; Rats; Rats, Wistar; Seizures | 2004 |
The nucleotide transporter MRP4 (ABCC4) is highly expressed in human platelets and present in dense granules, indicating a role in mediator storage.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Biological Transport; Blood Platelets; Cyclic GMP; Hermanski-Pudlak Syndrome; Humans; Multidrug Resistance-Associated Proteins; Secretory Vesicles; Vanadates | 2004 |
Activation of CD38 by interleukin-8 signaling regulates intracellular Ca2+ level and motility of lymphokine-activated killer cells.
Topics: Adenosine Diphosphate; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Antigens, CD; Blotting, Western; Calcium; Calcium Channels; Cell Line; Cell Movement; Cyclic ADP-Ribose; Cyclic GMP; Dose-Response Relationship, Drug; Gene Expression Regulation; Humans; Inositol 1,4,5-Trisphosphate Receptors; Interleukin-8; Killer Cells, Lymphokine-Activated; Kinetics; Membrane Glycoproteins; Models, Biological; Receptors, Cytoplasmic and Nuclear; Ryanodine Receptor Calcium Release Channel; Tetradecanoylphorbol Acetate; Time Factors | 2005 |
The NO/cGMP pathway inhibits Rap 1 activation in human platelets via cGMP-dependent protein kinase I.
Topics: Adenosine Diphosphate; Blood Platelets; Calcium Signaling; Cell Line; Collagen; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type I; Cyclic GMP-Dependent Protein Kinases; Humans; Megakaryocytes; Nitric Oxide; Nitric Oxide Donors; rap1 GTP-Binding Proteins; Transfection | 2005 |
NO-donors, part 9 : diazeniumdiolates inhibit human platelet aggregation and induce a transient vasodilatation of porcine pulmonary arteries in accordance with the NO-releasing rates.
Topics: Adenosine Diphosphate; Animals; Azo Compounds; Collagen; Cyclic GMP; Endothelium, Vascular; Guanylate Cyclase; Lasers; Magnetic Resonance Spectroscopy; Nitric Oxide; Nitric Oxide Donors; Platelet Aggregation; Platelet Aggregation Inhibitors; Pulmonary Artery; Swine; Vasodilation | 2005 |
Regulation of platelet guanylyl cyclase by collagen: evidence that Glycoprotein VI mediates platelet nitric oxide synthesis in response to collagen.
Topics: Adenosine Diphosphate; Blood Platelets; Calcium; Citrulline; Collagen; Cyclic GMP; Dose-Response Relationship, Drug; Fibrinogen; Guanylate Cyclase; Humans; Immunoblotting; Immunoprecipitation; Nitric Oxide; Nitric Oxide Synthase; Peptides; Phosphatidylinositol 3-Kinases; Platelet Activation; Platelet Membrane Glycoproteins; Protein Kinase C; Signal Transduction; src-Family Kinases; Thromboxane A2 | 2005 |
Loss of anti-aggregatory effects of aortic valve tissue in patients with aortic stenosis.
Topics: Adenosine Diphosphate; Aged; Alprostadil; Aortic Valve; Aortic Valve Insufficiency; Aortic Valve Stenosis; Biomarkers; Blood Platelets; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Epoprostenol; Female; Humans; Male; Middle Aged; Nitric Oxide; Platelet Aggregation; Platelet Aggregation Inhibitors; Research Design | 2006 |
Von Willebrand factor activates endothelial nitric oxide synthase in blood platelets by a glycoprotein Ib-dependent mechanism.
Topics: Adenosine Diphosphate; Blood Platelets; Calcium; Cell Adhesion Molecules; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Humans; In Vitro Techniques; Microfilament Proteins; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinases; Phospholipase C gamma; Phosphoproteins; Phosphorylation; Platelet Activation; Platelet Glycoprotein GPIb-IX Complex; Signal Transduction; src-Family Kinases; Thromboxane A2; von Willebrand Factor | 2006 |
Inhibition of ADP-induced platelet adhesion to immobilised fibrinogen by nitric oxide: evidence for cGMP-independent mechanisms.
Topics: Adenosine Diphosphate; Blood Platelets; Calcium; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Fibrinogen; Humans; Nitric Oxide; Phosphatidylinositol 3-Kinases; Phosphorylation; Platelet Adhesiveness; Platelet Glycoprotein GPIIb-IIIa Complex; Signal Transduction; Tyrosine | 2007 |
Cyclic nucleotide-dependent protein kinases inhibit binding of 14-3-3 to the GTPase-activating protein Rap1GAP2 in platelets.
Topics: 14-3-3 Proteins; Adenosine Diphosphate; Animals; Blood Platelets; Chlorocebus aethiops; COS Cells; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Epoprostenol; GTPase-Activating Proteins; HeLa Cells; Humans; Nitric Oxide; Phosphorylation; Platelet Adhesiveness; rap1 GTP-Binding Proteins; Signal Transduction; Thrombin | 2008 |
Oncocalyxone A inhibits human platelet aggregation by increasing cGMP and by binding to GP Ibalpha glycoprotein.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adolescent; Adult; Anthraquinones; Blood Platelets; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Female; Flow Cytometry; Guanylate Cyclase; Humans; In Vitro Techniques; Male; Middle Aged; Nitric Oxide; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIb-IX Complex; Protein Binding; Thromboxane A2 | 2008 |
The role of leucocytes in the acetyl salicylic acid (aspirin) induced nitric oxide synthesis in the production of interferon-alpha, a potent inhibitor of platelet aggregation and a thrombolytic agent.
Topics: Adenosine Diphosphate; Adult; Animals; Aspirin; Blood Platelets; Cyclic AMP; Cyclic GMP; Female; Fibrin; Fibrinolysis; Humans; Interferon-alpha; Leukocytes; Male; Mice; Middle Aged; Nitric Oxide; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet-Rich Plasma; Thrombosis | 2009 |
The role of calreticulin transacetylase in the activation of human platelet nitrite reductase by polyphenolic acetates.
Topics: Acetyltransferases; Adenosine Diphosphate; Antioxidants; Blood Platelets; Calreticulin; Coumarins; Cyclic GMP; Electrodes; Enzyme Activation; Flavonoids; Flow Cytometry; Humans; NADPH-Ferrihemoprotein Reductase; Nitric Oxide; Nitric Oxide Synthase; Nitrite Reductases; Phenols; Platelet Aggregation; Polyphenols | 2009 |
CNGA2 contributes to ATP-induced noncapacitative Ca2+ influx in vascular endothelial cells.
Topics: Adenine; Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Aminoquinolines; Aniline Compounds; Animals; Calcium Channel Blockers; Calcium Signaling; Cattle; Cells, Cultured; Cyclic GMP; Cyclic Nucleotide-Gated Cation Channels; Diltiazem; Endothelial Cells; Enzyme Inhibitors; Imines; Male; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; RNA Interference; Thionucleotides; Time Factors; Transfection; Vasodilation; Xanthenes | 2010 |
Pyridoxine increases nitric oxide biosynthesis in human platelets.
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Cardiovascular Diseases; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activation; Female; Humans; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Proto-Oncogene Proteins c-akt; Pyridoxine; Thrombin; Young Adult | 2009 |
Long-term treatment with atrial natriuretic peptide inhibits ATP production and insulin secretion in rat pancreatic islets.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Atrial Natriuretic Factor; Blotting, Western; Colforsin; Cyclic GMP; Enzyme-Linked Immunosorbent Assay; Glucose; In Vitro Techniques; Insulin; Islets of Langerhans; Keto Acids; Male; Potassium Chloride; Rats; Rats, Sprague-Dawley; Receptors, Atrial Natriuretic Factor; Reverse Transcriptase Polymerase Chain Reaction; RNA | 2011 |
Increased nitric oxide production in platelets from severe chronic renal failure patients.
Topics: Adenosine Diphosphate; Arginine; Blood Platelets; Case-Control Studies; Collagen; Cyclic GMP; Female; Fibrinogen; Humans; Inflammation; Kidney Failure, Chronic; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Platelet Aggregation | 2011 |
Glutathione peroxidase-3 deficiency promotes platelet-dependent thrombosis in vivo.
Topics: Adenosine Diphosphate; Animals; Antioxidants; Bleeding Time; Blood Platelets; Cyclic GMP; Disease Models, Animal; Endothelium, Vascular; Genotype; Glutathione; Glutathione Peroxidase; Infarction, Middle Cerebral Artery; Mice; Mice, Knockout; P-Selectin; Platelet Aggregation; Reactive Oxygen Species; Risk Factors; Thrombosis | 2011 |
A novel role of andrographolide, an NF-kappa B inhibitor, on inhibition of platelet activation: the pivotal mechanisms of endothelial nitric oxide synthase/cyclic GMP.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Calcium; Collagen; Cyclic GMP; Diterpenes; Humans; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type III; Platelet Activation; Platelet Aggregation Inhibitors; Protein Kinase Inhibitors; Protein Kinases; Pulmonary Embolism; Thromboxane A2 | 2011 |
Characterization of a unique dihydropyrimidinone, ethyl 4-(4'-heptanoyloxyphenyl)-6-methyl-3,4-dihydropyrimidin-2-one-5-carboxylate, as an effective antithrombotic agent in a rat experimental model.
Topics: Adenosine Diphosphate; Animals; Aorta; Aspirin; Blood Platelets; Collagen; Cyclic GMP; Drug Synergism; Inflammation Mediators; Inhibitory Concentration 50; Lipopolysaccharides; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Platelet Aggregation Inhibitors; Pyrimidinones; Rats; Rats, Sprague-Dawley; Thrombin; Thromboplastin; Thrombosis | 2011 |
Calreticulin Transacetylase mediated activation of human platelet nitric oxide synthase by acetyl group donor compounds.
Topics: Acetates; Acetylation; Acetyltransferases; Adenosine Diphosphate; Arginine; Blood Platelets; Cells, Cultured; Coumarins; Cyclic GMP; Cytochrome Reductases; Enzyme Inhibitors; Fluoresceins; Humans; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroprusside; Platelet Aggregation; Polyphenols; Structure-Activity Relationship | 2012 |
Platelet hyperaggregability in high-fat fed rats: a role for intraplatelet reactive-oxygen species production.
Topics: Adenosine Diphosphate; Animals; Antioxidants; Blood Platelets; Cyclic GMP; Diet, High-Fat; Enzyme Activation; Enzyme Activators; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Glucose Intolerance; Glucose Tolerance Test; Guanylate Cyclase; Insulin Resistance; Male; Nitric Oxide; Nitric Oxide Donors; Oxidative Stress; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Rats; Rats, Wistar; Reactive Oxygen Species; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase; Thrombin; Time Factors; Weight Gain | 2012 |
Mechanism of anti-platelet activity of Oligoporus tephroleucus oligoporin A: involvement of extracellular signal-regulated kinase phosphorylation and cyclic nucleotide elevation.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Calcium; Cyclic AMP; Cyclic GMP; Extracellular Signal-Regulated MAP Kinases; Fibrinogen; Glucosides; Humans; Male; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Rats; Rats, Sprague-Dawley; Signal Transduction; Triterpenes | 2012 |
The FleQ protein from Pseudomonas aeruginosa functions as both a repressor and an activator to control gene expression from the pel operon promoter in response to c-di-GMP.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Bacterial Proteins; Binding Sites; Cyclic GMP; DNA, Bacterial; Gene Expression Regulation, Bacterial; Operon; Promoter Regions, Genetic; Pseudomonas aeruginosa; Repressor Proteins; Trans-Activators | 2012 |
A novel antithrombotic effect of sulforaphane via activation of platelet adenylate cyclase: ex vivo and in vivo studies.
Topics: Adenosine Diphosphate; Adenylyl Cyclases; Animals; Blood Platelets; Cells, Cultured; Cyclic AMP; Cyclic GMP; Enzyme Activation; Fibrinolytic Agents; Humans; Isothiocyanates; Mice; Phosphatidylinositol 3-Kinases; Phospholipase C gamma; Platelet Activation; Proto-Oncogene Proteins c-akt; Signal Transduction; Sulfoxides | 2013 |
Soluble guanylyl cyclase is the only enzyme responsible for cyclic guanosine monophosphate synthesis in human platelets.
Topics: Adenosine Diphosphate; Blood Platelets; Cyclic GMP; Enzyme Activation; Enzyme Activators; Guanylate Cyclase; Humans; Natriuretic Peptides; Nitroprusside; Platelet Aggregation; Receptors, Cytoplasmic and Nuclear; Receptors, Guanylate Cyclase-Coupled; Soluble Guanylyl Cyclase | 2013 |
Blockade of the purinergic P2Y12 receptor greatly increases the platelet inhibitory actions of nitric oxide.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Blood Platelets; C-Reactive Protein; Calcium; Cell Adhesion Molecules; Cyclic AMP; Cyclic GMP; Enzyme Activation; Epoprostenol; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Microfilament Proteins; Models, Biological; Nitric Oxide; Phosphatidylinositol 3-Kinases; Phosphodiesterase Inhibitors; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prostaglandin-Endoperoxide Synthases; Purinergic P2Y Receptor Antagonists; rap1 GTP-Binding Proteins; Receptors, Purinergic P2Y12; Thrombin | 2013 |
Specific inhibitory effects of the NO donor MAHMA/NONOate on human platelets.
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Cell Adhesion Molecules; Collagen; Cyclic AMP; Cyclic GMP; Humans; Hydrazines; Microfilament Proteins; Middle Aged; Nitric Oxide Donors; Peptide Fragments; Phosphoproteins; Phosphorylation; Platelet Aggregation; Signal Transduction; Young Adult | 2014 |
The role of inhibition of nitric oxide synthesis in the aggregation of platelets due to the stimulated production of thromboxane A2.
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Cells, Cultured; Cyclic AMP; Cyclic GMP; Enzyme Inhibitors; Female; Humans; Kinetics; Male; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Platelet Aggregation; Thromboxane A2 | 2014 |
Cyclic di-GMP mediates a histidine kinase/phosphatase switch by noncovalent domain cross-linking.
Topics: Adenosine Diphosphate; Catalytic Domain; Caulobacter crescentus; Cyclic GMP; Histidine Kinase; Models, Molecular; Phosphoric Monoester Hydrolases; Protein Structure, Tertiary; Signal Transduction | 2016 |
The role of adenosine diphosphate mediated platelet responsiveness for the stability of platelet integrity in citrated whole blood under ex vivo conditions.
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Cell Adhesion Molecules; Cell Survival; Citric Acid; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Female; Fibrinogen; Gene Expression Regulation; Humans; Male; Microfilament Proteins; P-Selectin; Peptide Fragments; Phosphoproteins; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Primary Cell Culture; Protein Binding; Receptors, Purinergic P2X1; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12 | 2017 |
Cyclic-di-GMP and ADP bind to separate domains of PilB as mutual allosteric effectors.
Topics: Acidobacteria; Adenosine Diphosphate; Allosteric Regulation; Bacterial Proteins; Cyclic GMP; Models, Molecular; Oxidoreductases; Protein Binding; Protein Domains | 2020 |
Effects of bacterial lipopolysaccharides on platelet function: inhibition of weak platelet activation.
Topics: Adenosine Diphosphate; Adolescent; Adult; Biomarkers; Blood Platelets; Cyclic AMP; Cyclic GMP; Female; Flow Cytometry; Humans; Lipopolysaccharides; Male; Neutrophils; Platelet Activation; Platelet Aggregation; Platelet Function Tests; Signal Transduction; Young Adult | 2020 |
Inherited Retinal Degeneration: PARP-Dependent Activation of Calpain Requires CNG Channel Activity.
Topics: Adenosine Diphosphate; Animals; Calpain; Cyclic GMP; Cyclic Nucleotide-Gated Cation Channels; Mice; Nerve Tissue Proteins; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Retinal Degeneration; Ribose | 2022 |
Adenosine diphosphate-induced aggregation is enhanced in platelets obtained from patients with thrombotic primary antiphospholipid syndrome (t-PAPS): Role of P2Y
Topics: Adenosine Diphosphate; Antiphospholipid Syndrome; Blood Platelets; Cyclic AMP; Cyclic GMP; Humans; Iloprost; Nitroprusside; Platelet Aggregation; Platelet Aggregation Inhibitors; Signal Transduction | 2022 |