adenosine diphosphate has been researched along with arachidonic acid in 702 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 276 (39.32) | 18.7374 |
| 1990's | 161 (22.93) | 18.2507 |
| 2000's | 116 (16.52) | 29.6817 |
| 2010's | 127 (18.09) | 24.3611 |
| 2020's | 22 (3.13) | 2.80 |
| Authors | Studies |
|---|---|
| Colwell, JA; Halushka, PV; Nair, RM; Rogers, C; Sagel, J; Whetsell, A | 1 |
| Belushkina, NN; Severina, IS | 1 |
| de Nucci, G; Mitchell, JA; Vane, JR; Warner, TD | 1 |
| Akamatsu, N; Tanoue, K; Yamamoto, N; Yamazaki, H | 1 |
| Anfossi, G; Burzacca, S; Cavalot, F; Massucco, P; Mattiello, L; Mularoni, E; Trovati, M | 1 |
| Fitscha, P; O'Grady, J; Rauscha, F; Sinzinger, H; Virgolini, I | 1 |
| Kinlough-Rathbone, RL; Packham, MA | 1 |
| Carroll, RC; Rubinstein, E; Urso, I | 1 |
| Ko, FN; Lin, CN; Liou, SS; Teng, CM | 2 |
| Kasjanovová, D; Macejka, J | 1 |
| Ardlie, NG; Bartlett, MR; McGuiness, JA; Selley, ML | 1 |
| Tatarintsev, AV; Varfolomeyev, SD; Vrzheshch, PV; Yershov, DE | 1 |
| Huang, SC; Huang, TF; Li, HL; Teng, CM; Wu, TS | 1 |
| Akamatsu, N; Fujimoto, T; Katagiri, Y; Suzuki, H; Tanoue, K; Yamaguchi, A; Yamazaki, H | 1 |
| Himmelreich, G; Hundt, K; Neuhaus, P; Riess, H; Roissant, R | 1 |
| Ebihara, A; Fujimura, A; Ohashi, K | 1 |
| Jámbor, G; Kammerer, L; Romics, L; Szénási, P; Tóth, L | 1 |
| Imai, S; Ino, T; Mitsuoka, Y; Momo, K; Nakamura, K; Ohkubo, H; Someya, K; Tachiiri, T | 1 |
| Mase, K; Soga, T; Yasunaga, K; Yoshioka, M | 1 |
| Bin, Z; Kun, L | 1 |
| Ammit, AJ; O'Neill, C | 1 |
| Chi, LG; Kitzen, JM; Lucchesi, BR; Uprichard, AC | 1 |
| Moncada, S; Palmer, RM; Radomski, MW | 1 |
| Ageel, AM; al-Kharji, AM; el Tahir, KE | 1 |
| Bartonek, M; Lundholm, CE | 1 |
| Bullough, DA; Mullane, KM; Zhang, C | 1 |
| Inoue, M; Iwane, Y; Kobune, K; Kudo, T; Morikawa, M; Takanami, Y; Tsuboi, M | 1 |
| Akuzawa, M; Matumoto, M; Morizono, M; Okamoto, K; Yasuda, N | 1 |
| Dumenco, LL; Flanigan, TP; Foster, CB; Kazura, JW; Ratnoff, OD | 1 |
| Capecchi, PL; Ceccatelli, L; Di Perri, T; Gistri, A; Laghi Pasini, F; Mazza, S; Pasqui, AL | 1 |
| Takahashi, O | 1 |
| Corash, L; Nelson, GJ; Schmidt, PC | 1 |
| Ordinas, A | 1 |
| Benthin, G; Hillbom, M; Kaste, M; Laustiola, K; Muuronen, A; Numminen, H; Seppälä, E; Vapaatalo, H | 1 |
| Ahmed, Y; Elder, MG; Sullivan, MH | 1 |
| Corrigan, JJ; Glasser, L; Jeter, MA; Payne, CM; Tarantino, MD | 1 |
| Glusa, E | 1 |
| Brown, BR; Hall, SE; Han, WC; Harris, DN; Hedberg, A; Misra, RN; Webb, ML | 1 |
| Hattori, R; Kadota, K; Kawai, C; Murohara, Y; Yui, Y | 1 |
| Arita, H; Hayasaki, Y; Kakushi, H; Shike, T; Uchida, K | 1 |
| Cattaneo, M; Lecchi, A; Mannucci, PM; Tenconi, PM | 1 |
| Bozarth, JM; Chiu, AT; Mousa, SA; Pease, LJ; Reilly, TM; Roscoe, WA; Smith, RD; Timmermans, PB | 1 |
| Chute-Rose, L; Moake, J; Phillips, M; Turner, N; Vosburgh, E; Weinstein, M | 1 |
| Huang, ZS; Lee, TK | 1 |
| Rink, TJ; Sage, SO; Vindlacheruvu, RR | 1 |
| Kinjoh, K; Kosugi, T; Nakamura, M; Saitoh, S | 1 |
| Gilani, AH; Husnain, SQ; Saeed, SA; Suria, A | 1 |
| Dragan, YP; Ellis, EF | 1 |
| Botting, JH; Oyekan, AO | 1 |
| Pinto, A; Sorrentino, L; Sorrentino, R | 1 |
| Hatase, O; Itano, T; Ogata, K; Ohmori, S; Ohnaka, M; Sakaue, T; Tsuboi, S | 1 |
| Hakenkamp, K; Ryan, WL; Sullivan, E | 1 |
| Kambayashi, J; Kawasaki, T; Mori, T; Sakon, M; Shiba, E; Uemura, Y | 1 |
| Gilani, AH; Saeed, SA | 1 |
| Astley, N; Bonner, FW; Eason, CT; Pattison, A | 1 |
| Given, M; Lippton, H; Nambi, P; Ohlstein, EH; Storer, B | 1 |
| Benistant, C; Rubin, R | 1 |
| Li, XL; Steiner, M | 1 |
| César, JM; Espinosa, JI | 1 |
| Higashihara, M; Kariya, T; Kume, S; Matsumoto, Y; Ozaki, Y; Yatomi, Y | 1 |
| Cronholm, T; Norsten-Höög, C | 1 |
| Korbut, R; Lidbury, PS; Thiemermann, C; Vane, JR | 1 |
| Böshagen, H; Fiedler, VB; Perzborn, E; Rosentreter, U; Sander, E; Seuter, F; Stasch, JP; Weber, H | 1 |
| Beetens, J; De Clerck, F; Janssen, PA; Van Gorp, L; Verheyen, A | 1 |
| Anfossi, G; Emanuelli, G; Massucco, P; Mattiello, L; Mularoni, E; Trovati, M | 1 |
| Huang, TF; Ko, FN; Liu, YM; Sheu, SJ; Teng, CM | 1 |
| Cummins, D; Faint, R; Lerer, G; Machin, SJ; Maiztegui, JI; Molinas, FC | 1 |
| Banno, Y; Hirata, M; Kanoh, H; Nozawa, Y | 1 |
| Beilin, LJ; Croft, KD; Masarei, J; Rouse, I; Vandongen, R | 1 |
| Miller, VM; Vanhoutte, PM | 1 |
| Brace, LD; Le Breton, GC; Venton, DL | 2 |
| Benveniste, J; Chignard, M; Coëffier, E | 1 |
| Bühler, FR; Erne, P; Mittelholzer, E; Resink, TJ; Rogg, H | 1 |
| Barbenel, JC; Belch, JJ; Forbes, CD; Lowe, GD; Saniabadi, AR | 2 |
| Beyers, BJ; Bowen, RJ; King, T; Longenecker, GL | 1 |
| Atkinson, P; Chetty, N; Voll, CL | 1 |
| Barradas, MA; Dandona, P; Hoffbrand, AV; Jeremy, JY; Kontoghiorghes, GJ; Mikhailidis, DP | 1 |
| Palma-Carlos, AG; Palma-Carlos, ML; Santos, MC | 1 |
| Kanamaru, M; Nakashima, M | 1 |
| Bompiani, GD; Cardella, F; Davì, G; Giardina, E; Meli, F; Strano, A; Triolo, G | 1 |
| Feller, DR; Kim, SU; Newman, HA; Romstedt, KJ; Witiak, DT | 1 |
| Bleifeld, W; Kupper, W; Schuster, O; Terres, W | 1 |
| Caprino, L; Gallozzi, S; Togna, G | 1 |
| Isobe, J; Mizuno, A; Shima, K; Yano, M | 1 |
| Bardi, A; Ferroni, R; Franzé, D; Guarneri, M; Milani, L; Orlandini, P; Simoni, D | 1 |
| Arnout, J; Falcon, C; Vermylen, J | 1 |
| Ershov, DE; Fedorov, NA; Tatarintsev, AV; Varfolomeev, SD; Vrzheshch, PV; Zaĭtsev, SV | 1 |
| Benveniste, J; Bouloux, C; Chignard, M; Delautier, D; Lalau Keraly, C; Motte, G; Sebag, C | 1 |
| Chao, BH; Chow, EP; Harker, LA; Jakubowski, JA; Maraganore, JM; Marzec, UM; Savage, B | 1 |
| Azizova, OA; Borin, ML; Ivanova, MA; Khodorov, BI; Markov, CM; Pinelis, VG | 1 |
| Ewald, U; Kobbah, AM; Tuvemo, T | 1 |
| Bryant, NL; Guccione, MA; Kinlough-Rathbone, RL; Mustard, JF; Packham, MA | 1 |
| Cheng, KL; Huang, TF; Ko, FN; Lin, CN; Teng, CM | 1 |
| Cassaro, CM; Chamone, DA; Maeda, NY; Sampaio, CA; Sampaio, MU | 1 |
| Arosio, E; Guzzo, P; Lechi, A; Lechi, C; Minuz, P; Paluani, F; Sinigaglia, D | 1 |
| Bielawiec, M; Bodzenta-Lukaszyk, A; Gabryelewicz, A; Lukaszyk, A | 1 |
| Miele, L; Mukherjee, AB; Shulman, NR; Vostal, JG | 1 |
| D'Orléans-Juste, P; de Nucci, G; Vane, JR | 1 |
| Kondo, Y; Nazarea, M; Okajima, F; Sato, K; Sho, K | 1 |
| Alonso, MT; Garcia-Sancho, J; Sanchez, A | 1 |
| Gentry, PA; Liptrap, RM; Niemuller, C; Ross, ML | 1 |
| Goldenberg, HJ; Harris, DN; Heran, CL; Michel, IM; Ogletree, ML; Phillips, MB | 1 |
| Brüne, B; Ullrich, V | 1 |
| Srivastava, KC | 3 |
| Hollier, LH; Miller, VM; Reigel, MM; Vanhoutte, PM | 1 |
| Hammerschmidt, DE; Husak, M; Jacob, HS; Jeanneret, C; Lobell, M | 1 |
| Barzaghi, G; Cerletti, C; de Gaetano, G | 1 |
| Di Macco, G; Gazzaniga, PP; La Mancusa, R; Oddi, A; Pappalardo, G; Pulcinelli, FM; Reggio, D | 1 |
| Atlas, SA; De Caterina, R; Volpe, M; Weksler, BB | 1 |
| Lloyd, JV; Rodgers, SE; Russell, WJ | 1 |
| Asyee, GM; Schaap, MC; Sturk, A; ten Cate, JW; van Maanen, M | 1 |
| Ambler, J; Birch, J; Maguire, ED; Wallis, RB | 1 |
| Dal Bo Zanon, R; Fabris, F; Girolami, A; Luzzatto, G | 1 |
| Grande, P; Grauholt, AM; Wadt, J | 1 |
| Das, J; Vu, T | 1 |
| Kumahara, Y; Masugi, F; Oda, M; Ogihara, T; Saeki, S; Saito, K; Sakaguchi, K; Satouchi, K; Tokunaga, K | 1 |
| Das, J; Harris, DN; Ogletree, ML; Vu, T | 1 |
| Eldor, A; Heyns, Adu P; Marx, G; Yarom, R | 1 |
| Romstedt, K | 1 |
| Johnson, TL; Knowles, CO | 1 |
| Peerschke, EI | 1 |
| Cragoe, EJ; Johnson, SL; Limbird, LE; Sweatt, JD | 1 |
| Garber, DP; Greenberg, R; Harris, DN; Haslanger, MF; Nakane, M; Ogletree, ML; Reid, JA | 1 |
| Francis, GS; Johnson, GJ; Leis, LA | 1 |
| Inagaki, M; Meguro, T; Miura, T; Okada, Y; Saito, N; Taki, M; Tomita, Y; Tsuda, Y; Yamada, K | 1 |
| Armstrong, RA; Jones, RL; Wilson, NH | 1 |
| Mauss, EA; Zucker, MB | 1 |
| Brill', GE | 1 |
| Blair, IA; Cragoe, EJ; Limbird, LE; Sweatt, JD | 1 |
| Connolly, TM; Cragoe, EJ; Limbird, LE; Sweatt, JD | 1 |
| Cerbone, A; Cianciaruso, B; Cortese, A; Di Minno, G; Farace, MJ; Martinez, J; Murphy, S; Usberti, M | 1 |
| Braun, G; Brehm, G; Hiller, E; Riess, H | 1 |
| Kinlough-Rathbone, RL; Mustard, JF; Winocour, PD | 2 |
| Caen, J; Corvazier, E; Maclouf, J; Pintigny, D; Wautier, JL; Wautier, MP | 1 |
| Fuse, I; Hanano, M; Hattori, A; Higashihara, M; Koike, T; Nagayama, R; Shibata, A; Takahashi, H; Takeshige, T; Takizawa, S | 1 |
| Emms, H; Lewis, GP | 1 |
| Ando, T; Aoki, H; Iwami, M; Kohsaka, M; Nishikawa, M; Okamoto, M; Yoshida, K | 1 |
| Valone, FH | 1 |
| Bonner, FW; Eason, CT; Pattison, A | 1 |
| Calder, AA; Forbes, CD; Greer, IA; McLaren, M; Walker, JJ | 1 |
| Bucchi, F; Cerletti, C; de Gaetano, G; Del Maschio, A; Minoldo, S | 1 |
| Armitage, WJ | 1 |
| Macdonald, AG; Ogston, D; Price, RA | 1 |
| Benveniste, J; Braquet, P; Chignard, M; Korth, R; Le Couedic, JP; Norel, X; Nunez, D; Spinnewyn, B | 1 |
| Bernard, H; Boisseau, MR; Casadebaig, F; Dupin, JP; Gravier, D | 2 |
| Bellido, I; Camara, S; de la Cruz, JP; Martos, F; Sanchez de la Cuesta, F | 1 |
| Fertel, RH; Jacobs, RM; Murtaugh, RJ | 1 |
| Ishikawa, S; Manabe, S; Wada, O | 1 |
| Myers, A; Ramwell, P; Torres Duarte, AP | 1 |
| Johnson, PC; Salzman, EW; Smith, M; Ware, JA | 1 |
| Funayama, S; Hirokawa, Y; Komiyama, K; Oishi, S; Satoh, O; Tronquet, C; Umezawa, I | 1 |
| Ichikawa, Y; Kudo, Y; Nishino, K; Ohashi, M | 1 |
| Malmgren, R | 1 |
| Maurin, N | 1 |
| Lands, WE; Marshall, PJ | 1 |
| Frölich, JC; Küster, LJ | 1 |
| Burgess-Wilson, ME; Cockbill, SR; Heptinstall, S; Johnston, GI | 1 |
| Aurousseau, M; Benveniste, J; Chignard, M; Greiss, M; Lalau Keraly, C; Maamer, M | 1 |
| Lucas, FV; Skrinska, VA; Thomas, G | 1 |
| Catanese, B; Corradino, C; Picollo, R | 1 |
| Bellucci, S; Bryckaert, MC; Calvo, F; Camez, A; Dupuy, E; Tobelem, G | 1 |
| Berenger, FP; Cano, JP; Rolland, PH | 1 |
| Beattie, LL; Gerrard, JM; Israels, SJ; Park, J | 1 |
| Akkerman, JW; Kloprogge, E | 1 |
| Joseph, S; Kakkar, VV; Krishnamurthi, S | 1 |
| Jamaluddin, MP; Krishnan, LK | 1 |
| Harrison, P; Poole, CJ; Ross Russell, RW; Savidge, GF | 1 |
| Esterbauer, H; Hurst, JS; Juergens, G; Lang, J; Slater, TF; Zollner, H | 1 |
| Bellido, I; Camara, S; Carrasco, T; de la Cruz, JP; Sanchez de la Cuesta, F | 1 |
| Campana, G; Capuano, D; Chiariello, M; Delfanti, G | 1 |
| Chen, WY; Ko, WC; Ouyang, CH; Teng, CM | 1 |
| Fujita, T; Ohlstein, EH; Shebuski, RJ; Storer, B | 1 |
| Chaudhury, S; Macko, S; Rahimtula, AD | 1 |
| Bowie, EJ; Chesebro, JH; Lam, JY; Shimokawa, H; Vanhoutte, PM | 1 |
| Bydlowski, SP; Rymaszewski, Z; Subbiah, MT; Yunker, RL | 1 |
| Bell, RM; Greenberg, CS; Hannun, YA | 1 |
| Hayashi, Y; Hirasawa, N; Ohuchi, K; Sugidachi, A; Tsurufuji, S; Watanabe, M | 1 |
| Arya, LS; Pati, H; Rai, R; Saraya, AK | 1 |
| Herold, M; Kogelnig, R; Kunz, F; Zwierzina, WD | 1 |
| Gentry, PA; Ross, ML; Socha, AS | 1 |
| Deykin, D; Faigel, D; Jakubowski, JA; Stampfer, MJ; Vaillancourt, R | 1 |
| Bosia, A; Ghigo, D; Losche, W; Pannocchia, A; Pescarmona, G; Till, U; Treves, S | 1 |
| Hara, H; Inoue, T; Kakushi, H; Maruyama, T; Mihara, S; Okabayashi, T; Shike, T; Shirai, D; Takeda, Y; Uchida, K | 1 |
| Ahmed, MA; Al-Mohaya, SA; Al-Sheikh, EH; Al-Sohaibani, MO; Knox-Macaulay, H; Sumer, T | 1 |
| Feller, DR; Kamanna, VS; Kim, SK; Kim, SU; McCreery, RL; Newman, HA; Romstedt, KJ; Sternitzke, KD; Tehim, AK; Witiak, DT | 1 |
| Andries, R; Bourgain, RH; Braquet, P; Decuyper, K | 1 |
| Allen, BT; Anderson, CB; Freeman, MB; McGoff, MA; Sicard, GA; Valentin, LI | 1 |
| D'Alonzo, L; Di Gregorio, M; Izzi, L; Nubile, G; Ridolfi, D | 1 |
| Hillbom, M; Neiman, J | 1 |
| Fraser Mustard, J; Kinlough-Rathbone, RL; Packham, MA; Rand, ML | 1 |
| Cucuianu, MP; Deamer, DW; Edwards, B; Lascu, I | 1 |
| Bimmler, M; Donath, E; Egger, M; Glaser, R; Spangenberg, P; Till, U | 1 |
| Bahakim, H; Edrees, YB; Gaafar, TH; Gader, AM; Jabbar, FA; Lambourne, AL | 1 |
| Ardlie, NG; Boatwright, C; Garrett, J; McGuiness, JA | 1 |
| Bertelé, V; Castagnoli, MN; Cerletti, C; de Gaetano, G; Rajtar, G | 1 |
| Eddy, LJ; Longenecker, GL; Panus, PC | 1 |
| Gewirtz, H; Most, AS; Sasken, H; Steiner, M | 1 |
| Benveniste, J; Billerey, M; Buonocore, M; Chignard, M; Driss, F; Juhan-Vague, I; Poisson, C; Roul, C; Vague, P | 1 |
| Glusa, E; Herbst, I; Nowak, G; Schreiber, S | 1 |
| Caprino, L; Cebo, B; Dolci, N; Tempesta, E; Togna, AR; Togna, G | 1 |
| Hirai, A; Kitagawa, H; Takenaga, M; Tamura, Y; Yoshida, S | 1 |
| Horwitz, PM; Hyman, AL; Ignarro, LJ; Kadowitz, PJ; Landry, AZ; Lippton, HL; McNamara, DB | 1 |
| Ma, YH; Ouyang, CH; Teng, CM | 1 |
| Andries, R; Bourgain, RH; Deby, C | 1 |
| Ankerst, J; Fäldt, R; Zoucas, E | 1 |
| Brooks, DP; Chesney, CM; Crofton, JT; Huch, KM; Pifer, DD; Share, L | 1 |
| Atkinson, PM; Bradlow, BA; Chetty, N | 1 |
| Jackson, ML; Olexson, DW; Searcy, GP | 1 |
| Chambers, JK; Colwell, JA; Halushka, PV; Loadholt, CB; Lopes-Virella, M; Mayfield, RK; Wohltmann, HJ | 1 |
| Rubanyi, GM; Vanhoutte, PM | 1 |
| Altman, R; Rouvier, J; Weisenberger, H | 1 |
| Allen, AD; Bhatnagar, AS; Choi, S; el-Sabban, F; Nelson, GH; Rosenblum, WI | 1 |
| Rao, GH; White, JG | 2 |
| Burke, JF; De La Rosa, J; Di Minno, G; Martinez, J; McKean, ML; Murphy, S | 1 |
| De Clerck, F; Herman, AG; Laekeman, GM; Vlietinck, AJ | 1 |
| Atkinson, PM; Chetty, N; Taylor, DI | 1 |
| Humphries, DE; Nesbitt, JP; Silbert, CK; Silbert, JE | 1 |
| Landolfi, R; Motola, NC; Steiner, M; Turcotte, JG | 1 |
| Andries, R; Bourgain, RH; Braquet, P; Deby, C | 1 |
| Crawford, J; Heptinstall, S; MacPherson, M; Morrison, R | 1 |
| Carter, AJ; Heptinstall, S | 1 |
| De Bellis Vitti, G; Dejana, E; Delaini, F; Donati, MB; Poggi, A; Reyers, I; Vicenzi, E | 1 |
| Calder, AA; Forbes, CD; Greer, IA; Walker, JJ | 1 |
| Giles, TD; Given, MB; Sander, GE | 1 |
| Wada, O; Yanagisawa, H | 1 |
| Isert, D; Róka, L | 1 |
| Al-Sinawi, LA; Burke, C; Hassan, S; Hedges, A; Mekki, QA; Moody, SG; Moti, MJ; O'Grady, J; Whittle, BJ | 1 |
| Leytin, VL; Mazurov, AV; Repin, VS; Tkachuk, VA | 1 |
| Hall, ER; Pan, IQ; Wu, KK | 1 |
| Beckett, C; Daniel, JL; Day, HJ; Hassel, B; Holmsen, H; Koike, K; Rao, AK; Smith, JB; Willis, J | 1 |
| Cazenave, JP; Hemmendinger, S; Wiesel, ML | 1 |
| Chamberlain, PD; Nunn, B | 1 |
| Reading, HW; Rosie, R; Whalley, LJ | 1 |
| MacDonald, ML; Morris, JG; Rogers, QR | 1 |
| Kerry, R; Scrutton, MC; Wallis, RB | 1 |
| Ehrlich, YH; Kornecki, E; Lenox, RH | 1 |
| Favilla, S; Fortini, A; Gensini, GF; Prisco, D | 1 |
| Furchgott, RF | 1 |
| Jones, R; Machin, SJ; Mackie, IJ | 1 |
| Martin, TJ; Smith, IL | 1 |
| Di Minno, G; Martinez, J; Murphy, S; Perussia, B; Shapiro, S; Thiagarajan, P; Trinchieri, G | 1 |
| Greenberg, R; Harris, DN; Haslanger, MF; Powell, J; Snitman, D; Sprague, PW; Vu, T | 1 |
| Radha, E; Rao, GH; White, JG | 1 |
| Dangelmaier, CA; Holmsen, H; Holmsen, HK | 1 |
| Antonaccio, MJ; Goldenberg, HJ; Harris, DN; Heikes, JE; Michel, IM; Phillips, MB; Sprague, PW | 1 |
| Guccione, MA; Harfenist, EJ; Kinlough-Rathbone, RL; Mustard, JF; Packham, MA | 1 |
| Cattaneo, M; Chahil, A; Kinlough-Rathbone, RL; Lam, SC; Mustard, JF; Packham, MA; Perry, DW; Vickers, JD | 1 |
| Aonuma, S; Fujimoto, S; Kohama, Y; Nomura, M; Yamahata, E | 1 |
| Bradlow, BA; Chetty, N; Gibson, JE; Mendelsohn, D; van der Westhuyzen, J | 1 |
| Böhlke, H; Flohé, L; Frankus, E; Kim, SM; Lintz, W; Loschen, G; Michel, G; Müller, B; Schneider, J; Seipp, U | 1 |
| Le Breton, GC; Parise, LV; Venton, DL | 1 |
| Cockbill, SR; Cowley, AJ; Hanley, SP; Heptinstall, S; Jones, EW | 1 |
| Goto, J; Iwata, H; Masukawa, T | 1 |
| Browning, JD; Gordon, PR; O'Dell, BL | 1 |
| Inada, Y; Nishikawa, K; Nomura, H; Terashita, Z; Tsushima, S; Yoshioka, Y | 1 |
| Cameron, JS; Duffus, P; Frampton, G; Livio, M; Marchesi, D; Parbtani, A; Remuzzi, G | 1 |
| Nakamizo, N; Shuto, K; Yamada, K | 1 |
| Castaldi, PA; Chong, BH; Grace, CS; Rozenberg, MC | 1 |
| Lee, TC; Malone, B; Snyder, F | 1 |
| Catalano, PM; De Marco, L; Di Minno, G; Murphy, S; Shapiro, SS | 1 |
| Borda, E; Gimeno, AL; Gimeno, MF; Lazzari, MA; Shattner, MA | 1 |
| Cockrell, CS; Ellis, EF; Nelson, GH; Rosenblum, WI | 1 |
| Chumakova, ZV; Kazanskaia, LV; Lomazova, KD; Poliakova, AM; Tur'ianov, MKh | 1 |
| Kowalski, KA; Leid, RW; McConnell, LA; Sadoff, DA | 1 |
| Maddox, WT; McDaniel, HG; Poon, MC; Rackley, CE; Rogers, WJ | 1 |
| Dickson, VM; Feuerstein, IA | 1 |
| Dahl, ML; Matintalo, M; Uotila, P | 1 |
| Apitz-Castro, R; Cabrera, S; Cruz, MR; Jain, MK; Ledezma, E | 1 |
| Bell, TG; Deyo, JA; Hilliker, KS; Roth, RA | 1 |
| Leĭtin, VL; Mazurov, AV; Repin, VS; Rozenshtraukh, LV; Smirnov, VN | 1 |
| Lüscher, EF; Steiner, M | 2 |
| Clemmons, RM; Meyers, KM | 1 |
| Ishikawa, M; Kodaira, H; Komoda, Y; Nakajima, T | 1 |
| Kerry, PJ; Paton, CJ | 1 |
| Chan, CC; Ford-Hutchinson, AW; Hall, RA; Nathaniel, DJ; Yusko, PJ | 1 |
| Butter, DB; Graham, MF; Haubold, AD; Hung, TC; Lewis, JH; Zhao, JQ | 1 |
| Dugdale, M; Johnson, RW; Lasslo, A; Naylor, JL; Quintana, RP | 1 |
| Srivas, KC | 1 |
| Mansouri, A; Perry, CA | 1 |
| Bernini, W; Chierchia, S; Crea, F; De Caterina, R; Gazzetti, P; Giannessi, D; L'Abbate, A | 1 |
| Rotman, A | 1 |
| Brammer, JP; Maguire, MH | 1 |
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| Henskens, YMC; Houben, R; Kuiper, GJAJM; Lancé, MD; Oerle, RV; Ten Cate, H; Verhezen, PWM; Wetzels, RJH | 1 |
| Rubenstein, DA; Soaita, I; Yin, W | 1 |
| Jia, J; Jiang, H; Liao, J; Ling, LQ; Niu, Q; Wang, X; Zhou, J; Zuo, CH | 1 |
| Bangalore, R; DePalma, L; Hase, T; Maluso, P; Sarani, B; Sirajuddin, S | 1 |
| Biolik, G; Kokot, M; Pawlicki, K; Święszek, A; Sznapka, M; Ziaja, D; Ziaja, K | 1 |
| Chin, CM; Dos Santos, JL; Dutra, LA; Guanaes, JFO; Johmann, N; Lopes Pires, ME; Marcondes, S | 1 |
| Antonopoulou, S; Laios, K; Moschos, MM; Moustafa, GA; Papakonstantinou, VD; Tsatsos, M | 1 |
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| Enko, D; Mahla, E; Mangge, H; Prüller, F; Riegler, A; Rosskopf, K; von Lewinski, D; Weiss, EC | 1 |
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| Al Mamary, A; Campello, E; Dalla Valle, F; Maggiolo, S; Napodano, M; Piazza, D; Simioni, P; Spiezia, L | 1 |
| Fu, H; Fu, J; Lu, H; Luo, Y; Ma, S; Wang, W; Xu, H; Zhang, Z; Zhu, X | 1 |
| Chen, H; Chen, S; Jiang, H; Jin, YX; Ling, LQ; Liu, CN; Yang, XC; Zhou, J | 1 |
| Huang, WJ; Li, JM; Liu, HC; Xie, D; Zhang, YC; Zuo, J | 1 |
| Al-Masri, AA; Al-Yahya, AM; El Eter, EA; Hersi, A; Lateef, R; Mawlana, O | 1 |
| Calfee, CS; Callcut, RA; Cohen, MJ; Conroy, AS; Fields, AT; Hendrickson, CM; Kornblith, LZ; Robles, AJ | 1 |
| Guillotte, AR; Hammer, RD; Herbert, JP; Litofsky, NS; Madsen, R | 1 |
| Al-Samkari, H; Kuter, DJ; Van Cott, EM | 1 |
| Hvas, AM; Nissen, PH; Skipper, MT | 1 |
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| Ge, JB; Qian, JY; Wang, QB; Wu, HY; Zhang, C; Zhao, X | 1 |
| Bryant, SC; Jaffe, AS; Karon, BS; Katzman, BM; Scott, RJ; Wockenfus, AM | 1 |
| Gager, GM; Hengstenberg, C; Jilma, B; Kolesnik, E; Lang, IM; Prüller, F; Siller-Matula, JM; Toma, A; von Lewinski, D; Wallner, M; Winter, MP | 1 |
| Guo, L; Huang, Q; Shi, X; Wang, G; Yang, Y; Yuan, D; Yuan, Y; Zhang, H; Zhao, Y | 1 |
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| Baucom, MR; England, L; Goodman, MD; Pritts, TA; Schuster, R; Turner, K; Wallen, TE; Youngs, J | 1 |
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| Baczek, T; Karolczak, K; Konieczna, L; Kostanek, J; Kostka, T; Soltysik, B; Watala, C; Witas, PJ | 1 |
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| Chatzigiannis, CM; Gkalpinos, V; Kostagianni, AD; Kostomitsopoulos, N; Papakyriakopoulou, P; Tellis, CC; Tselepis, AD; Tsiailanis, AD; Tzakos, AG; Valsami, G | 1 |
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15 review(s) available for adenosine diphosphate and arachidonic acid
| Article | Year |
|---|---|
Interaction of platelets and blood vessels--vascular injuries induced by platelet activation in vivo.
Topics: Adenosine Diphosphate; Animals; Antibodies, Monoclonal; Arachidonic Acid; Blood Platelets; Blood Vessels; Endothelium, Vascular; Intracranial Embolism and Thrombosis; Male; Platelet Activation; Platelet Aggregation; Rabbits; Vacuoles | 1992 |
Heterogeneity of endothelium-dependent responses in mammalian blood vessels.
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Vessels; Bradykinin; Catecholamines; Endothelium; Humans; Hypoxia; In Vitro Techniques; Platelet Aggregation; Serotonin; Thrombin; Vasopressins | 1985 |
Role of paf-acether and related ether-lipid metabolism in platelets.
Topics: Acetyltransferases; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Cyclic AMP; Glycerylphosphorylcholine; Histamine Release; Humans; Hydrolysis; Phospholipases A; Platelet Activating Factor; Platelet Aggregation; Serotonin; Thrombin | 1985 |
Role of thromboxane A2.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Epinephrine; Humans; Indomethacin; Kinetics; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Receptors, Prostaglandin; Receptors, Thromboxane; Serotonin; Thrombin; Thromboxane A2; Thromboxane B2 | 1985 |
The platelet fibrinogen receptor.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Binding Sites; Blood Platelets; Cations, Divalent; Collagen; Epinephrine; Fibrinogen; Fibronectins; Glycoproteins; Humans; Kinetics; Membrane Proteins; Platelet Aggregation; Platelet Membrane Glycoproteins; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Receptors, Cell Surface; Thrombin; Thrombospondins; von Willebrand Factor | 1985 |
Characterization of thromboxane receptors in human platelets.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Binding, Competitive; Blood Platelets; Chemical Phenomena; Chemistry; Cyclic AMP; Humans; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Prostaglandins, Synthetic; Radioligand Assay; Receptors, Cell Surface; Receptors, Prostaglandin; Receptors, Thromboxane; Structure-Activity Relationship; Thromboxane A2 | 1985 |
Current treatment for thrombotic diseases.
Topics: Adenosine Diphosphate; Animals; Anticoagulants; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Clinical Trials as Topic; Cyclic AMP; Epinephrine; Fibrinolytic Agents; Heparin; Humans; Thrombin; Thrombosis; Vitamin K | 1984 |
The role of endothelium in the responses of vascular smooth muscle to drugs.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetophenones; Acetylcholine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Calcimycin; Catechols; Endothelium; Histamine; Hydroquinones; Hypoxia; Masoprocol; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Prostaglandins; Quinacrine; Serotonin; Substance P; Thrombin | 1984 |
In vitro methods and the study of platelet mechanisms.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cell Survival; Collagen; Cytoplasmic Granules; Endothelium; Glycoproteins; Hemostasis; Humans; In Vitro Techniques; Membrane Proteins; Platelet Adhesiveness; Platelet Aggregation; Thrombin | 1981 |
[Update on the treatment with platelet antiaggregation agents].
Topics: Abciximab; Adenosine Diphosphate; Antibodies, Monoclonal; Arachidonic Acid; Cell Membrane; Eptifibatide; Humans; Immunoglobulin Fab Fragments; Peptides; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prostaglandin-Endoperoxide Synthases; Thromboxane A2; Tirofiban; Tyrosine | 2001 |
[Significance of platelet function tests].
Topics: Adenosine Diphosphate; Arachidonic Acid; Aspirin; Blood Platelet Disorders; Clopidogrel; Collagen; Hemorrhagic Disorders; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Prognosis; Ristocetin; Ticlopidine | 2010 |
Influence of omega-3 polyunsaturated fatty acid-supplementation on platelet aggregation in humans: a meta-analysis of randomized controlled trials.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Collagen; Dietary Supplements; Fatty Acids, Omega-3; Health Status; Humans; Middle Aged; Platelet Aggregation; Randomized Controlled Trials as Topic | 2013 |
The predictive value of multiple electrode platelet aggregometry (multiplate) in adult cardiac surgery.
Topics: Adenosine Diphosphate; Adult; Aged; Arachidonic Acid; Blood Transfusion; Cardiac Surgical Procedures; Female; Humans; Male; Middle Aged; Peptide Fragments; Platelet Aggregation; Platelet Function Tests; Point-of-Care Systems; Postoperative Hemorrhage; Predictive Value of Tests; Retrospective Studies; Time Factors; Treatment Outcome | 2013 |
[Impact of acute normovolemic hemodilution on primary hemostasis].
Topics: Adenosine Diphosphate; Arachidonic Acid; Blood Component Transfusion; Blood Transfusion, Autologous; Hemodilution; Hemostasis; Humans; Hydrogen-Ion Concentration; Observational Studies as Topic; Platelet Aggregation | 2014 |
Sex-Related Differences in Platelet Aggregation: A Literature Review Supplemented with Local Data from a Group of Generally Healthy Individuals.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Arachidonic Acid; Aspirin; Blood Platelets; Female; Humans; Lactones; Male; Platelet Aggregation; Platelet Aggregation Inhibitors | 2023 |
56 trial(s) available for adenosine diphosphate and arachidonic acid
| Article | Year |
|---|---|
The influence of fenflumizole on platelet aggregation in patients with unstable angina pectoris.
Topics: Adenosine Diphosphate; Adult; Aged; Angina Pectoris; Angina, Unstable; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; beta-Thromboglobulin; Clinical Trials as Topic; Collagen; Female; Humans; Imidazoles; Male; Middle Aged; Platelet Aggregation; Platelet Factor 4; Thromboxane B2; Verapamil | 1987 |
Platelet aggregation in human whole blood after chronic administration of aspirin.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Cells; Cell Separation; Collagen; Dose-Response Relationship, Drug; Epinephrine; Humans; In Vitro Techniques; Male; Platelet Aggregation; Research Design | 1987 |
Vitamin E supplementation effect on human platelet function, arachidonic acid metabolism, and plasma prostacyclin levels.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Chromatography, High Pressure Liquid; Collagen; Epoprostenol; Female; Food, Fortified; Humans; Hydroxyeicosatetraenoic Acids; Male; Platelet Aggregation; Radioimmunoassay; Thromboxane B2; Vitamin E | 1988 |
A chemically stable analogue, 9 beta-methyl carbacyclin, with similar effects to epoprostenol (prostacyclin, PGI2) in man.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Bleeding Time; Blood Coagulation; Blood Platelets; Collagen; Cyclic AMP; Epoprostenol; Hemodynamics; Humans; In Vitro Techniques; Infusions, Parenteral; Male; Platelet Aggregation | 1984 |
Current treatment for thrombotic diseases.
Topics: Adenosine Diphosphate; Animals; Anticoagulants; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Clinical Trials as Topic; Cyclic AMP; Epinephrine; Fibrinolytic Agents; Heparin; Humans; Thrombin; Thrombosis; Vitamin K | 1984 |
Correction of uremic platelet dysfunction after renal transplantation.
Topics: Actins; Adenosine Diphosphate; Adult; Aged; Arachidonic Acid; Collagen; Cytoskeleton; Epinephrine; Female; Humans; In Vitro Techniques; Kidney Transplantation; Male; Middle Aged; Platelet Aggregation; Renal Dialysis; Ristocetin; Uremia | 1995 |
A study of platelet functions, some hemostatic and fibrinolytic parameters in relation to serotonin in hemodialyzed patients under erythropoietin therapy.
Topics: Adenosine Diphosphate; Adult; Anemia; Arachidonic Acid; Biomarkers; Bleeding Time; Blood Platelets; Blood Proteins; Erythropoietin; Female; Fibrinolysis; Hematocrit; Hemoglobins; Hemostasis; Humans; Kidney Failure, Chronic; Male; Middle Aged; Platelet Aggregation; Recombinant Proteins; Renal Dialysis; Ristocetin; Serotonin; Thromboembolism; Time Factors | 1995 |
Effect of diltiazem and low-dose aspirin on platelet aggregation and ATP release induced by paired agonists.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adult; Arachidonic Acid; Aspirin; Bleeding Time; Blood Platelets; Diltiazem; Drug Synergism; Epinephrine; Female; Humans; Male; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors | 1993 |
Platelet aggregation in patients with atrial fibrillation taking aspirin or warfarin.
Topics: Adenosine Diphosphate; Arachidonic Acid; Aspirin; Atrial Fibrillation; Cerebrovascular Disorders; Collagen; Epinephrine; Humans; In Vitro Techniques; Kinetics; Platelet Aggregation; Warfarin | 1993 |
Alterations in platelet function in patients receiving interleukin-6 as cytokine therapy.
Topics: Adenosine Diphosphate; Antineoplastic Agents; Arachidonic Acid; Blood Platelets; Enzyme-Linked Immunosorbent Assay; Epinephrine; Humans; In Vitro Techniques; Infusions, Intravenous; Injections, Intravenous; Interleukin-6; Kinetics; Neoplasms; Platelet Aggregation; Platelet Count; Platelet Factor 4; Radioimmunoassay; Thromboxane B2 | 1996 |
Anti-platelet effects of 100 mg alternate day oral aspirin: a randomized, double-blind, placebo-controlled trial of regular and enteric coated formulations in men and women.
Topics: Adenosine Diphosphate; Administration, Oral; Adult; Arachidonic Acid; Aspirin; Blood Platelets; Cardiovascular Diseases; Double-Blind Method; Drug Administration Schedule; Epinephrine; Epoprostenol; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Radioimmunoassay; Risk Factors; Thromboxanes | 1996 |
The influence of antioxidant nutrients on platelet function in healthy volunteers.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adult; Alprostadil; Antioxidants; Arachidonic Acid; Ascorbic Acid; beta Carotene; beta-Thromboglobulin; Blood Platelets; Collagen; Double-Blind Method; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Vitamin E | 1997 |
Platelet responses to several agonists and combinations of agonists in whole blood: a placebo controlled comparison of the effects of a once daily dose of plain aspirin 300 mg, plain aspirin 75 mg and enteric coated aspirin 300 mg, in man.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Aspirin; Blood Platelets; Coagulants; Collagen; Dose-Response Relationship, Drug; Epinephrine; Female; Humans; Male; Placebos; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Ristocetin; Streptokinase; Tablets, Enteric-Coated | 1997 |
The effect of dietary docosahexaenoic acid on platelet function, platelet fatty acid composition, and blood coagulation in humans.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Blood Coagulation; Blood Platelets; Collagen; Dietary Fats, Unsaturated; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids; Humans; Longitudinal Studies; Male; Platelet Aggregation; Prothrombin Time | 1997 |
Effect of policosanol on platelet aggregation and serum levels of arachidonic acid metabolites in healthy volunteers.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Adult; Anticholesteremic Agents; Arachidonic Acid; Collagen; Epoprostenol; Fatty Alcohols; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Thromboxane B2 | 1998 |
The inhibitory effect of cinchonine on human platelet aggregation due to blockade of calcium influx.
Topics: Adenosine Diphosphate; Antimalarials; Arachidonic Acid; Calcimycin; Calcium; Cinchona Alkaloids; Collagen; Epinephrine; Humans; Platelet Activating Factor; Platelet Aggregation Inhibitors; Reference Values; Signal Transduction | 1998 |
Effect of policosanol on platelet aggregation in type II hypercholesterolemic patients.
Topics: Adenosine Diphosphate; Anticholesteremic Agents; Arachidonic Acid; Collagen; Double-Blind Method; Fatty Alcohols; Female; Humans; Hyperlipoproteinemia Type II; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors | 1998 |
Platelet function during cardiac surgery and cardiopulmonary bypass with low-dose aprotinin.
Topics: Adenosine Diphosphate; Aprotinin; Arachidonic Acid; Blood Platelets; Blood Transfusion; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Female; Hemostatics; Humans; Male; Middle Aged; P-Selectin; Platelet Activation; Platelet Aggregation; Platelet Count; Platelet Glycoprotein GPIIb-IIIa Complex; Postoperative Hemorrhage; Prospective Studies; Ristocetin; Single-Blind Method | 1999 |
Effect of salicis cortex extract on human platelet aggregation.
Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Collagen; Double-Blind Method; Female; Furosemide; Humans; Low Back Pain; Male; Medicine, Traditional; Middle Aged; Phytotherapy; Plant Extracts; Plant Stems; Plants, Medicinal; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Portugal | 2001 |
Platelet aggregation in different antithrombotic regimens. Possible proaggregant effect of low level oral anticoagulation.
Topics: Acenocoumarol; Adenosine Diphosphate; Aged; Analysis of Variance; Anticoagulants; Arachidonic Acid; Atrial Fibrillation; Blood Platelets; Collagen; Embolism; Female; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Salicylates; Time Factors | 2002 |
Celecoxib does not affect the antiplatelet activity of aspirin in healthy volunteers.
Topics: Adenosine Diphosphate; Adolescent; Adult; Arachidonic Acid; Aspirin; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Interactions; Female; Humans; Isoenzymes; Male; Membrane Proteins; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Thromboxane B2 | 2002 |
The COX-2 selective inhibitor, valdecoxib, does not impair platelet function in the elderly: results of a randomized controlled trial.
Topics: Adenosine Diphosphate; Aged; Aged, 80 and over; Arachidonic Acid; Bleeding Time; Blood Platelets; Collagen; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Humans; Ibuprofen; Isoenzymes; Isoxazoles; Male; Membrane Proteins; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Thromboxane B2 | 2003 |
Combination antiplatelet therapy in patients with peripheral vascular bypass grafts.
Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Blood Vessel Prosthesis; Clopidogrel; Drug Therapy, Combination; Female; Flow Cytometry; Graft Occlusion, Vascular; Humans; Male; Middle Aged; Peripheral Vascular Diseases; Platelet Activation; Platelet Aggregation Inhibitors; Ticlopidine | 2004 |
Prospective evaluation of the relationship between platelet-leukocyte conjugate formation and recurrent myocardial ischemia in patients with acute coronary syndromes.
Topics: Adenosine Diphosphate; Adrenergic beta-Antagonists; Aged; Angina, Unstable; Arachidonic Acid; Aspirin; Blood Platelets; C-Reactive Protein; Cell Aggregation; Drug Resistance; Eptifibatide; Female; Heparin; Humans; Leukocytes; Male; Middle Aged; Monocytes; Multivariate Analysis; Myocardial Infarction; Myocardial Ischemia; Neutrophils; Patient Selection; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prospective Studies; Receptors, Thrombin; Recurrence; ROC Curve; Tirofiban; Treatment Outcome; Troponin I; Tyrosine | 2004 |
The specific thromboxane receptor antagonist S18886: pharmacokinetic and pharmacodynamic studies.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Administration, Oral; Aged; Arachidonic Acid; Area Under Curve; Collagen; Female; Humans; Kinetics; Male; Middle Aged; Naphthalenes; Platelet Aggregation; Platelet Aggregation Inhibitors; Propionates; Receptors, Thromboxane; Time Factors | 2005 |
Effect of fast-food Mediterranean-type diet on type 2 diabetics and healthy human subjects' platelet aggregation.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Blood Platelets; Body Weight; Diabetes Mellitus, Type 2; Diet; Diet, Mediterranean; Energy Intake; Food Analysis; Humans; Lipids; Middle Aged; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Reference Values; Restaurants | 2006 |
Enhanced antiplatelet effect of clopidogrel in patients whose platelets are least inhibited by aspirin: a randomized crossover trial.
Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Biomarkers; Clopidogrel; Collagen; Cross-Over Studies; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Nephelometry and Turbidimetry; Peripheral Vascular Diseases; Platelet Activation; Platelet Aggregation Inhibitors; Ticlopidine | 2005 |
Sex differences in platelet reactivity and response to low-dose aspirin therapy.
Topics: Adenosine Diphosphate; Arachidonic Acid; Aspirin; Cardiovascular Diseases; Collagen; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Epinephrine; Female; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Regression Analysis; Sex Factors | 2006 |
Influence on platelet aggregation of i.v. parecoxib and acetaminophen in healthy volunteers.
Topics: Acetaminophen; Adenosine Diphosphate; Adult; Analgesics, Non-Narcotic; Arachidonic Acid; Blood Platelets; Cross-Over Studies; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Interactions; Epinephrine; Humans; Infusions, Intravenous; Isoxazoles; Male; Platelet Aggregation; Thromboxane B2 | 2006 |
Celecoxib, ibuprofen, and the antiplatelet effect of aspirin in patients with osteoarthritis and ischemic heart disease.
Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Celecoxib; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Ibuprofen; Male; Middle Aged; Myocardial Ischemia; Osteoarthritis; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Pyrazoles; Sulfonamides; Thromboxane B2; Treatment Outcome | 2006 |
Effect of traditional Greek Mediterranean meals on platelet aggregation in normal subjects and in patients with type 2 diabetes mellitus.
Topics: Adenosine Diphosphate; Adult; Aged; Arachidonic Acid; Diabetes Mellitus, Type 2; Diet, Mediterranean; Female; Greece; Humans; Male; Middle Aged; Platelet Activating Factor; Platelet Aggregation; Thrombin | 2006 |
Normalization of platelet reactivity in clopidogrel-treated subjects.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Aspirin; Blood Platelets; Clopidogrel; Collagen; Coronary Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fibrinogen; Humans; Male; Pilot Projects; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Transfusion; Platelet-Rich Plasma; Postoperative Hemorrhage; Receptors, Thrombin; Recovery of Function; Reference Values; Ticlopidine; Time Factors | 2007 |
Evaluation of dose-related effects of aspirin on platelet function: results from the Aspirin-Induced Platelet Effect (ASPECT) study.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Aspirin; Blood Platelets; Collagen; Coronary Disease; Cross-Over Studies; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Drug Resistance; Female; Flow Cytometry; Humans; Male; Middle Aged; Nephelometry and Turbidimetry; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Prospective Studies; Thrombelastography; Thromboxane B2 | 2007 |
Platelet function measured by VerifyNow identifies generalized high platelet reactivity in aspirin treated patients.
Topics: Adenosine Diphosphate; Aged; Aged, 80 and over; Arachidonic Acid; Aspirin; Collagen; Coronary Artery Disease; Cross-Over Studies; Double-Blind Method; Female; Fibrinogen; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Function Tests; von Willebrand Factor | 2007 |
Variable responsiveness to clopidogrel and aspirin among patients with acute coronary syndrome as assessed by platelet function tests.
Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Adult; Aged; Arachidonic Acid; Aspirin; Clopidogrel; Female; Humans; Male; Middle Aged; Nephelometry and Turbidimetry; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet-Rich Plasma; ROC Curve; Sensitivity and Specificity; Ticlopidine | 2008 |
Relationship between high platelet turnover and platelet function in high-risk patients with coronary artery disease on dual antiplatelet therapy.
Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Arachidonic Acid; Blood Platelets; Coronary Artery Disease; Coronary Thrombosis; Drug Resistance; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Platelet Function Tests; Treatment Outcome | 2008 |
Delayed inhibition of agonist-induced granulocyte-platelet aggregation after low-dose sevoflurane inhalation in humans.
Topics: Adenosine Diphosphate; Administration, Inhalation; Adult; Anesthetics, Inhalation; Arachidonic Acid; Blood Coagulation; Blood Platelets; Cross-Over Studies; Dose-Response Relationship, Drug; Flow Cytometry; Granulocytes; Humans; Male; Methyl Ethers; P-Selectin; Peptide Fragments; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIb-IX Complex; Platelet Membrane Glycoprotein IIb; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2Y12; Receptors, Thrombin; Receptors, Thromboxane A2, Prostaglandin H2; Research Design; Sevoflurane; Thrombelastography; Time Factors | 2008 |
Increased platelet sensitivity among individuals with aspirin resistance - platelet aggregation to submaximal concentration of arachidonic acid predicts response to antiplatelet therapy.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Aspirin; Blood Platelets; Collagen; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Resistance; Female; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Receptors, Thromboxane; Reference Values; Thromboxane B2; Treatment Failure | 2008 |
Effects of aspirin and clopidogrel in healthy men measured by platelet aggregation and PFA-100.
Topics: Adenosine Diphosphate; Adolescent; Adult; Arachidonic Acid; Aspirin; Clopidogrel; Collagen; Cross-Over Studies; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Resistance; Epinephrine; Humans; Male; Middle Aged; Nephelometry and Turbidimetry; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Reference Values; Ticlopidine | 2008 |
Effect of increased aspirin dose after stenting in association with ClOpidogrel: the FIASCO randomized study.
Topics: Adenosine Diphosphate; Aged; Angina Pectoris; Arachidonic Acid; Aspirin; Blood Platelets; Clopidogrel; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Prospective Studies; Ticlopidine; Time Factors; Treatment Outcome | 2009 |
Thrombotic events in high risk patients are predicted by evaluating different pathways of platelet function.
Topics: Adenosine Diphosphate; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Arachidonic Acid; Aspirin; Clopidogrel; Collagen; Drug Resistance; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Likelihood Functions; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Point-of-Care Systems; Predictive Value of Tests; Prospective Studies; Reproducibility of Results; Risk Assessment; Risk Factors; ROC Curve; Thrombosis; Ticlopidine | 2008 |
Low molecular weight heparin significantly reduces embolisation after carotid endarterectomy--a randomised controlled trial.
Topics: Adenosine Diphosphate; Aged; Anticoagulants; Arachidonic Acid; Aspirin; Carotid Artery Diseases; Dalteparin; Double-Blind Method; Drug Therapy, Combination; Endarterectomy, Carotid; Female; Hemorrhage; Heparin; Humans; Infusions, Intravenous; Intracranial Embolism; Male; Middle Aged; Odds Ratio; Platelet Aggregation; Platelet Aggregation Inhibitors; Risk Assessment; Stroke; Time Factors; Treatment Outcome; Ultrasonography, Doppler, Transcranial | 2009 |
Cross validation of the Multiple Electrode Aggregometry. A prospective trial in healthy volunteers.
Topics: Adenosine Diphosphate; Adult; Alprostadil; Arachidonic Acid; Aspirin; Clopidogrel; Electrodes; Female; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Ticlopidine; Time Factors; Young Adult | 2009 |
Gender differences in platelet aggregation in healthy individuals.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Black or African American; Collagen; Epinephrine; Female; Hispanic or Latino; Humans; Male; Platelet Aggregation; Platelet Function Tests; Reference Values; Sex Factors; Texas; White People; Young Adult | 2010 |
A point-of-care assessment of the effects of desmopressin on impaired platelet function using multiple electrode whole-blood aggregometry in patients after cardiac surgery.
Topics: Adenosine Diphosphate; Aged; Aged, 80 and over; Arachidonic Acid; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Deamino Arginine Vasopressin; Drug Monitoring; Feasibility Studies; Female; Hemostatics; Humans; Male; Peptide Fragments; Platelet Aggregation; Point-of-Care Systems; Postoperative Hemorrhage; Predictive Value of Tests; Prospective Studies; Time Factors; Treatment Outcome | 2010 |
Variability and persistence of aspirin response in lower extremity peripheral arterial disease patients.
Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Angioplasty, Balloon; Arachidonic Acid; Aspirin; Azetidines; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Lower Extremity; Male; Middle Aged; Niacin; Peripheral Arterial Disease; Placebo Effect; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Stents; Time Factors; Treatment Outcome | 2011 |
Increased platelet aggregation and in vivo platelet activation after granulocyte colony-stimulating factor administration. A randomised controlled trial.
Topics: Adenosine Diphosphate; Adolescent; Adult; Arachidonic Acid; Blood Platelets; Cardiovascular Diseases; Female; Granulocyte Colony-Stimulating Factor; Humans; Male; Middle Aged; Neoplasms; P-Selectin; Peptide Fragments; Platelet Aggregation; Recombinant Proteins; Ristocetin; Sex Factors; Thrombosis | 2011 |
Reversal of the anti-platelet effects of aspirin and clopidogrel.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Aspirin; Biomarkers; Blood Platelets; Clopidogrel; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Ontario; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Transfusion; Recovery of Function; Thromboxane B2; Ticlopidine; Time Factors | 2012 |
Effects of acepromazine maleate on platelet function assessed by use of adenosine diphosphate activated- and arachidonic acid- activated modified thromboelastography in healthy dogs.
Topics: Acepromazine; Adenosine Diphosphate; Animals; Arachidonic Acid; Blood Platelets; Cross-Over Studies; Dogs; Female; Hemostasis; Hypnotics and Sedatives; Injections, Intravenous; Thrombelastography | 2012 |
The in vitro effects of verbascoside on human platelet aggregation.
Topics: Adenosine Diphosphate; Adult; Aged; Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Blood Platelets; Coronary Disease; Female; Glucosides; Humans; Male; Middle Aged; Phenols; Platelet Aggregation | 2012 |
Platelet mapping as part of modified thromboelastography (TEG®) in patients undergoing cardiac surgery and cardiopulmonary bypass.
Topics: Adenosine Diphosphate; Aged; Algorithms; Arachidonic Acid; Blood Coagulation Tests; Blood Platelets; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Collagen; Female; Humans; Male; Middle Aged; Pilot Projects; Platelet Aggregation; Platelet Function Tests; Prospective Studies; ROC Curve; Thrombelastography | 2012 |
Aspirin attenuates platelet activation and immune activation in HIV-1-infected subjects on antiretroviral therapy: a pilot study.
Topics: Adenosine Diphosphate; Adult; Aged; Anti-HIV Agents; Arachidonic Acid; Aspirin; Cells, Cultured; Collagen; Female; HIV Infections; HIV-1; Humans; Inflammation; Lymphocyte Activation; Male; Middle Aged; P-Selectin; Pilot Projects; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Thromboxanes; Young Adult | 2013 |
Temporal variability in the antiplatelet effects of clopidogrel and aspirin after elective drug-eluting stent implantation. An ADAPT-DES substudy.
Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Blood Vessel Prosthesis Implantation; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Elective Surgical Procedures; Female; Germany; Humans; Male; Middle Aged; Observer Variation; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Receptors, Purinergic P2Y12; Ticlopidine | 2015 |
Effect of Vorapaxar Alone and in Combination with Aspirin on Bleeding Time and Platelet Aggregation in Healthy Adult Subjects.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Aspirin; Bleeding Time; Blood Coagulation Tests; Drug Therapy, Combination; Female; Healthy Volunteers; Humans; Lactones; Male; Middle Aged; Platelet Aggregation; Pyridines; Receptors, Thrombin; Young Adult | 2016 |
Differential Effects of Clopidogrel With or Without Aspirin on Platelet Reactivity and Coagulation Activation: A Randomized Trial in Healthy Volunteers.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Aspirin; beta-Thromboglobulin; Blood Coagulation; Blood Platelets; Cell Adhesion Molecules; Clopidogrel; Drug Therapy, Combination; Healthy Volunteers; Humans; Male; Microfilament Proteins; P-Selectin; Phosphoproteins; Platelet Aggregation Inhibitors; Thromboxane B2; Whole Blood Coagulation Time; Young Adult | 2021 |
Platelet inhibition by low-dose aspirin is not influenced by body mass or weight.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Aspirin; Blood Platelets; Body Weight; Collagen; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests | 2022 |
632 other study(ies) available for adenosine diphosphate and arachidonic acid
| Article | Year |
|---|---|
Platelet adhesion and aggregation in diabetes mellitus.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Blood Coagulation Factors; Blood Platelets; Diabetes Mellitus; Factor VIII; Humans; Imidazoles; Insulin; Male; Platelet Activating Factor; Platelet Adhesiveness; Platelet Aggregation; von Willebrand Factor | 1979 |
Increase in activating ability of human platelet guanylate cyclase during aggregation.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arginine; Blood Platelets; Cyclic GMP; Enzyme Activation; Guanylate Cyclase; Humans; Nitroprusside; Platelet Aggregation; Protoporphyrins | 1992 |
Different patterns of release of endothelium-derived relaxing factor and prostacyclin.
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Arachidonic Acid; Arginine; Bradykinin; Cattle; Endothelium, Vascular; Epoprostenol; Hydrogen-Ion Concentration; In Vitro Techniques; Nitric Oxide; Rabbits; Radioimmunoassay; Substance P | 1992 |
Normal aggregations of glycoprotein IV (CD36)-deficient platelets from seven healthy Japanese donors.
Topics: Adenosine Diphosphate; Adolescent; Adult; Amino Acid Sequence; Antigens, CD; Arachidonic Acid; Blood Platelets; CD36 Antigens; Collagen; Epinephrine; Female; Flow Cytometry; Humans; Immunoelectrophoresis; Immunoglobulin Fab Fragments; Iodine Radioisotopes; Japan; Male; Middle Aged; Molecular Sequence Data; Platelet Aggregation; Protein Deficiency; Thrombin | 1992 |
Studies on the effect of dopamine on the human platelet response.
Topics: Adenosine Diphosphate; Adrenergic alpha-Antagonists; Adult; Arachidonic Acid; beta-Thromboglobulin; Blood Platelets; Collagen; Dopamine; Dopamine Agents; Dopamine Antagonists; Humans; In Vitro Techniques; Male; P-Selectin; Platelet Aggregation; Platelet Factor 4; Platelet Membrane Glycoproteins; Receptors, Adrenergic, alpha; Serotonin | 1992 |
Modification of platelet function by isosorbide dinitrate in patients with coronary artery disease.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; beta-Thromboglobulin; Blood Platelets; Coronary Disease; Drug Interactions; Endothelium, Vascular; Epoprostenol; Female; Humans; Hypertension; Isosorbide Dinitrate; Male; Middle Aged; Platelet Activation; Platelet Aggregation; Platelet Factor 4; Risk Factors; Smoking; Thromboxane A2 | 1992 |
Unexpected effects of aurin tricarboxylic acid on human platelets.
Topics: Adenosine Diphosphate; Arachidonic Acid; Aurintricarboxylic Acid; Blood Platelets; Calcimycin; Collagen; Humans; In Vitro Techniques; Platelet Aggregation; Platelet Aggregation Inhibitors; Ristocetin; Serotonin; Thrombin | 1992 |
Low concentrations of sodium azide specifically inhibit a thromboxane A2 pathway in human platelets.
Topics: Adenosine Diphosphate; Apyrase; Arachidonic Acid; Aspirin; Azides; Blood Platelets; Calcium; Collagen; Energy Metabolism; Enzyme Activation; Humans; Hydrogen-Ion Concentration; Myosin-Light-Chain Kinase; Platelet Activation; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Secretory Rate; Serotonin; Sodium Azide; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2 | 1992 |
Gamma-pyrone compounds. II: Synthesis and antiplatelet effects of tetraoxygenated xanthones.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Cells, Cultured; Collagen; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Structure-Activity Relationship; Xanthenes | 1992 |
The effect of extracts from garden radish (Raphanus sativus) and horseradish (Amoracia rusticana) on platelet functional activity in vitro.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Blood Platelets; Epinephrine; Humans; In Vitro Techniques; Plant Extracts; Platelet Aggregation; Platelet Aggregation Inhibitors; Radioimmunoassay; Thromboxane B2 | 1992 |
Effect of anethole dithiolthione on human platelet aggregation.
Topics: Adenosine Diphosphate; Adult; Anethole Trithione; Arachidonic Acid; Aspirin; Butylated Hydroxytoluene; Humans; In Vitro Techniques; Platelet Aggregation; Platelet Aggregation Inhibitors; Radioimmunoassay; Thrombin; Thromboxane B2 | 1992 |
Cell response kinetics: the phenomenon of supercooperativity in aggregation of human platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Arachidonic Acid; Calcimycin; Epinephrine; Humans; Kinetics; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Tetradecanoylphorbol Acetate; Thimerosal | 1992 |
Antiplatelet actions of some coumarin compounds isolated from plant sources.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Blood Platelets; Coumarins; Membrane Lipids; Molecular Structure; Phospholipids; Plants; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Rabbits; Thrombin; Thromboxane B2 | 1992 |
Decreased platelet aggregation after reperfusion in orthotopic liver transplantation.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Collagen; Erythrocyte Aging; Female; Humans; Liver Transplantation; Male; Middle Aged; Platelet Aggregation; Platelet Count; Reperfusion; Ristocetin | 1992 |
Daily variations in platelet aggregation and adhesion in healthy subjects.
Topics: Adenosine Diphosphate; Adult; Analysis of Variance; Arachidonic Acid; Circadian Rhythm; Collagen; Epinephrine; Humans; Hydrocortisone; In Vitro Techniques; Male; Platelet Adhesiveness; Platelet Aggregation; Platelet Count; Reference Values | 1992 |
Platelet function in male diabetics with and without macrovascular complications.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Blood Glucose; Blood Pressure; Cholesterol; Collagen; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Epinephrine; Glycated Hemoglobin; Humans; In Vitro Techniques; Male; Middle Aged; Platelet Aggregation; Reference Values; Risk Factors; Smoking | 1992 |
Effects of the new antiplatelet agent 2-methyl-3-(1,4,5,6-tetrahydronicotinoyl)pyrazolo[1,5-a]pyridine on platelet aggregation and thrombosis in experimental animals.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Aspirin; Bridged Bicyclo Compounds; Cyclooxygenase Inhibitors; Dogs; Electroencephalography; Female; Fibrinolytic Agents; Guinea Pigs; Humans; In Vitro Techniques; Indomethacin; Male; Mice; Mice, Inbred ICR; Nicotinic Acids; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Rats; Rats, Inbred Strains; Respiration; Stomach Ulcer | 1992 |
[Clinical and preclinical pharmacology of KC-764, a novel antiplatelet agent].
Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; Bridged Bicyclo Compounds; Cerebral Infarction; Collagen; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Humans; Nicotinic Acids; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandins | 1992 |
Inhibition by glaucocalyxin A of aggregation of rabbit platelets induced by ADP, arachidonic acid and platelet-activating factor, and inhibition of [3H]-PAF binding.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Blood Platelets; Diterpenes, Kaurane; Drugs, Chinese Herbal; Female; Glyceryl Ethers; In Vitro Techniques; Kinetics; Male; Molecular Structure; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Thiazoles | 1992 |
Platelet-activating factor (PAF) receptor antagonists inhibit arachidonic acid induced platelet aggregation in rabbit whole blood.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Azepines; Dose-Response Relationship, Drug; In Vitro Techniques; Kinetics; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Structure-Activity Relationship; Triazoles | 1991 |
Effects of combined thromboxane synthetase inhibition/thromboxane receptor antagonism in two models of sudden cardiac death in the canine: limited role for thromboxane.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Arrhythmias, Cardiac; Collagen; Coronary Disease; Death, Sudden; Disease Models, Animal; Dogs; Electric Stimulation; Electrophysiology; Female; Heart Rate; Male; Pentanoic Acids; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Pyridines; Receptors, Prostaglandin; Receptors, Thromboxane; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes | 1990 |
Characterization of the L-arginine:nitric oxide pathway in human platelets.
Topics: Adenosine Diphosphate; Amino Acid Oxidoreductases; Arachidonic Acid; Arachidonic Acids; Arginine; Blood Platelets; Calcimycin; Humans; In Vitro Techniques; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Ornithine; Platelet Aggregation; Platelet Aggregation Inhibitors; Stereoisomerism; Thrombin | 1990 |
Influence of diethylcarbamazine and mefloquine on PGI2 synthesis by the rat thoracic aorta and myometrial tissues.
Topics: Adenosine Diphosphate; Animals; Aorta, Thoracic; Arachidonic Acid; Blood Pressure; Diethylcarbamazine; Dinoprostone; Epoprostenol; Female; Mefloquine; Muscle, Smooth, Vascular; Myometrium; Pregnancy; Rats; Rats, Inbred Strains | 1991 |
A study of the effects of p,p'-DDE and other related chlorinated hydrocarbons on inhibition of platelet aggregation.
Topics: Adenosine Diphosphate; Arachidonic Acid; Blood Platelets; Cyclooxygenase Inhibitors; DDT; Dichlorodiphenyl Dichloroethylene; Dichlorodiphenyldichloroethane; Humans; Hydrocarbons, Chlorinated; Platelet Aggregation; Platelet Aggregation Inhibitors | 1991 |
Acadesine (AICA riboside) inhibits platelet aggregation in human whole blood.
Topics: Adenosine Diphosphate; Aminoimidazole Carboxamide; Arachidonic Acid; Collagen; Dipyridamole; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Ribonucleosides | 1991 |
Effects of combination therapy with low-dose aspirin and warfarin on platelet functions after heart valve replacement.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adult; Aged; Arachidonic Acid; Aspirin; Bleeding Time; Blood Platelets; Calcium; Collagen; Drug Therapy, Combination; Female; Heart Valve Prosthesis; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Prostaglandin Endoperoxides, Synthetic; Thromboembolism; Ticlopidine; Warfarin | 1991 |
Persistent hematomas in Japanese black cattle with impaired platelet aggregation function and large granule eosinophils.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Cattle; Cattle Diseases; Collagen; Cytoplasmic Granules; Eosinophils; Epinephrine; Female; Hematoma; Immunoenzyme Techniques; Muscular Diseases; Partial Thromboplastin Time; Pedigree; Platelet Aggregation; Platelet Count; Prothrombin Time; Ristocetin; Serotonin; Skin Diseases; Thrombin | 1991 |
Inhibition of the activation of Hageman factor (factor XII) and of platelet aggregation by extracts of Brugia malayi microfilariae.
Topics: Adenosine Diphosphate; Adult; Animals; Arachidonic Acid; Arachidonic Acids; Blood Coagulation; Brugia; Collagen; Ellagic Acid; Factor XII; Humans; In Vitro Techniques; Male; Partial Thromboplastin Time; Platelet Aggregation; Platelet Aggregation Inhibitors; Trypsin | 1991 |
Nitroprusside in vitro inhibits platelet aggregation and intracellular calcium translocation. Effect of haemoglobin.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcium; Collagen; Hemoglobins; Humans; In Vitro Techniques; Intracellular Fluid; Nitroprusside; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors | 1991 |
Some properties of rat platelet aggregation and effects of butylated hydroxytoluene, warfarin and aspirin.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Coagulation Factors; Butylated Hydroxytoluene; Collagen; Epinephrine; Male; Platelet Activating Factor; Platelet Aggregation; Rats; Rats, Inbred Strains; Ristocetin; Warfarin | 1991 |
The effect of a salmon diet on blood clotting, platelet aggregation and fatty acids in normal adult men.
Topics: Adenosine Diphosphate; Adult; Animals; Arachidonic Acid; Arachidonic Acids; Blood Coagulation; Collagen; Dietary Proteins; Fatty Acids; Fatty Acids, Unsaturated; Humans; Male; Middle Aged; Partial Thromboplastin Time; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Prothrombin Time; Reference Values; Salmon; Thrombin | 1991 |
Platelet antiaggregate activity.
Topics: Adenosine Diphosphate; Adolescent; Adult; Arachidonic Acid; Arachidonic Acids; Female; Humans; Male; Migraine Disorders; Nicardipine; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors | 1991 |
Effects of exercise and ethanol ingestion on platelet thromboxane release in healthy men.
Topics: Adenosine Diphosphate; Adult; Alcohol Drinking; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Blood Pressure; Exercise; Heart Rate; Humans; Male; Platelet Aggregation; Reference Values; Thromboxane B2; von Willebrand Factor | 1991 |
Detection of platelet desensitization in pregnancy-induced hypertension is dependent on the agonist used.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Collagen; Female; Humans; Hypertension; Platelet Activating Factor; Platelet Aggregation; Pregnancy; Pregnancy Complications, Cardiovascular; Reference Values | 1991 |
A variant form of thrombasthenia.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Child; Child, Preschool; Collagen; Female; Humans; Male; Microscopy, Electron; Platelet Aggregation; Platelet Membrane Glycoproteins; Ristocetin; Thrombasthenia | 1991 |
Platelet aggregation in recombinant-hirudin-anticoagulated blood.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Citrates; Citric Acid; Collagen; Drug Synergism; Epinephrine; Hirudins; Humans; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Recombinant Proteins; Serotonin | 1991 |
Interphenylene 7-oxabicyclo[2.2.1]heptane thromboxane A2 antagonists. Semicarbazone omega-chains.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Fatty Acids, Unsaturated; Humans; Hydrazines; Magnetic Resonance Spectroscopy; Mice; Semicarbazones; Stereoisomerism; Thromboxane A2 | 1991 |
Human serum albumin inhibits prostacyclin production by endothelial cells: the relation of the inhibitory activity to sulfhydryl groups in albumin.
Topics: Adenosine Diphosphate; Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Bradykinin; Calcimycin; Calcium; Cattle; Cells, Cultured; Endothelium, Vascular; Epoprostenol; Extracellular Space; Humans; Ionomycin; Serum Albumin | 1991 |
[Effect of (+)-S-145 calcium salt dihydrate, an orally active antagonist of the thromboxane A2/prostaglandin endoperoxide receptor, on platelet aggregation].
Topics: Adenosine Diphosphate; Administration, Oral; Animals; Arachidonic Acid; Bridged Bicyclo Compounds; Collagen; Dose-Response Relationship, Drug; Epinephrine; Fatty Acids, Monounsaturated; Guinea Pigs; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Receptors, Prostaglandin | 1991 |
In vitro effects of picotamide on human platelet aggregation, the release reaction and thromboxane B2 production.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Arachidonic Acid; Aspirin; Blood Platelets; Collagen; Drug Interactions; Female; Humans; Male; Malondialdehyde; Phthalic Acids; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Sulfonamides; Thromboxane B2 | 1991 |
Inhibition of the thrombin-platelet reactions by DuP 714.
Topics: Adenosine Diphosphate; Arachidonic Acid; Blood Platelets; Boron Compounds; Collagen; Epinephrine; Fibrinogen; Hirudins; Humans; Kinetics; Oligopeptides; Platelet Aggregation; Platelet Membrane Glycoproteins; Thrombin | 1991 |
Isolation from commercial aurintricarboxylic acid of the most effective polymeric inhibitors of von Willebrand factor interaction with platelet glycoprotein Ib. Comparison with other polyanionic and polyaromatic polymers.
Topics: Adenosine Diphosphate; Anions; Arachidonic Acid; Aurintricarboxylic Acid; Collagen; Molecular Structure; Molecular Weight; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Polymers; Ristocetin; von Willebrand Factor | 1991 |
Comparison of in vitro platelet aggregation and its inhibition by three antithrombotic drugs between human and guinea pig.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Aspirin; Collagen; Dipyridamole; Guinea Pigs; Humans; Pentoxifylline; Platelet Aggregation; Platelet Aggregation Inhibitors; Species Specificity; Thrombin | 1991 |
Lack of evidence for a role for the lipoxygenase pathway in increases in cytosolic calcium evoked by ADP and arachidonic acid in human platelets.
Topics: Adenosine Diphosphate; Affinity Labels; Arachidonic Acid; Blood Platelets; Calcium; Cyclooxygenase Inhibitors; Cytosol; Egtazic Acid; Fura-2; Humans; Lipoxygenase; Lipoxygenase Inhibitors | 1991 |
Changes of rabbit platelet function on simultaneous administration of ticlopidine hydrochloride and OKY-046.
Topics: Adenosine Diphosphate; Administration, Oral; Animals; Arachidonic Acid; Collagen; Drug Interactions; Drug Synergism; Methacrylates; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Statistics as Topic; Ticlopidine | 1991 |
Effect of histamine receptor blockers on human platelet aggregation.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Collagen; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; In Vitro Techniques; Platelet Activating Factor; Platelet Aggregation | 1990 |
Effect of adenine nucleotides on cyclooxygenase and lipoxygenase enzyme products of arachidonic acid in human platelets.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adult; Arachidonate 12-Lipoxygenase; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Guanosine Triphosphate; Humans; Hydroxyeicosatetraenoic Acids; Prostaglandin-Endoperoxide Synthases; Uridine Triphosphate | 1990 |
Indium-111 oxine technique of studying platelet aggregation in vivo. Some physiological considerations.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Dose-Response Relationship, Radiation; Hydroxyquinolines; Indium Radioisotopes; Isotope Labeling; Lung; Male; Organometallic Compounds; Oxyquinoline; Platelet Aggregation; Radionuclide Imaging; Rats; Rats, Inbred Strains; Reproducibility of Results; Thrombin | 1990 |
Levamisole inhibits in vivo rat platelet aggregation by a release of prostacyclin-like factor.
Topics: Adenosine Diphosphate; Animals; Aorta, Thoracic; Arachidonic Acid; Arachidonic Acids; Aspirin; Collagen; Epoprostenol; Half-Life; In Vitro Techniques; Leukocytes; Levamisole; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Inbred Strains; Thromboxane A2 | 1990 |
Inhibition of platelet aggregation by S-(1,2-dicarboxyethyl)glutathione, intrinsic tripeptide in liver, heart, and lens.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Coagulation; Calcium; Collagen; Glutathione; Heart; Humans; Lens, Crystalline; Liver; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombin | 1990 |
A new platelet function test.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Aspirin; Bleeding Time; Blood Specimen Collection; Calcium; Collagen; Edetic Acid; Humans; Platelet Aggregation; Platelet Count; Platelet Function Tests; Ristocetin | 1990 |
The correlation between Ca2+ influx and inositol 1, 4, 5-trisphosphate (IP3) formation in platelets stimulated by various agonists.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcium; Humans; Inositol 1,4,5-Trisphosphate; Ionomycin; Platelet Activating Factor; Temperature; Thrombin; Thromboxane A2 | 1990 |
A comparative study of the effects of local anaesthetics on platelet aggregation.
Topics: Adenosine Diphosphate; Anesthetics, Local; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Humans; In Vitro Techniques; Membrane Lipids; Platelet Activating Factor; Platelet Aggregation | 1990 |
A comparison of the effects of three positive inotropic agents (amrinone, milrinone and medorinone) on platelet aggregation in human whole blood.
Topics: Adenosine Diphosphate; Amiodarone; Arachidonic Acid; Arachidonic Acids; Cardiotonic Agents; Collagen; Fibrinolytic Agents; Humans; Male; Milrinone; Naphthyridines; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyridazines; Pyridones | 1990 |
Endothelin and platelet function.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcium; Collagen; Dogs; Endothelins; Epinephrine; Humans; Peptides; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Rabbits; Thrombin | 1990 |
Ethanol inhibits thrombin-induced secretion by human platelets at a site distinct from phospholipase C or protein kinase C.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcium; Diglycerides; Enzyme Activation; Ethanol; Humans; Indomethacin; Inositol Phosphates; Ionomycin; Microscopy, Electron; Phosphatidic Acids; Platelet Activation; Protein Kinase C; Serotonin; Tetradecanoylphorbol Acetate; Thrombin; Type C Phospholipases | 1990 |
Fish oil: a potent inhibitor of platelet adhesiveness.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Epinephrine; Fatty Acids; Female; Fibrinogen; Fish Oils; Humans; Kinetics; Male; Microscopy, Electron; Microscopy, Electron, Scanning; Middle Aged; Platelet Adhesiveness; Platelet Aggregation | 1990 |
[Studies of aggregation using pairs of agonists in platelet concentrates stored for 5 days. Influence of autologous fresh plasma].
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Blood Preservation; Blood Transfusion, Autologous; Collagen; Epinephrine; Humans; Plasma; Platelet Aggregation | 1990 |
Effects of various inhibitors on platelet activation induced by TP 82, a CD 9 monoclonal antibody.
Topics: Adenosine Diphosphate; Aequorin; Amino Acid Sequence; Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation; Arachidonic Acid; Arachidonic Acids; Aspirin; Calcium; Dose-Response Relationship, Drug; Humans; Membrane Glycoproteins; Molecular Sequence Data; Oligopeptides; Platelet Activation; Serotonin; Tetraspanin 29; Thromboxane A2 | 1990 |
Analysis of aldehydic lipid peroxidation products in rat liver and hepatocytes by gas chromatography and mass spectrometry of the oxime-tert-butyldimethylsilyl derivatives.
Topics: Adenosine Diphosphate; Aldehydes; Animals; Arachidonic Acid; Arachidonic Acids; Chromatography, Gas; Ethanol; Female; Ferric Compounds; Gas Chromatography-Mass Spectrometry; Lipid Peroxidation; Liver; Mass Spectrometry; Oxidation-Reduction; Oximes; Rats; Rats, Inbred Strains; Silicon | 1990 |
Endothelins release tissue plasminogen activator and prostanoids.
Topics: Adenosine Diphosphate; Anesthesia; Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Collagen; Endothelins; Fibrinolytic Agents; Heart Rate; Hemodynamics; In Vitro Techniques; Indomethacin; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandins; Rabbits; Tissue Plasminogen Activator | 1990 |
Characterization of Bay U 3405, a novel thromboxane A2/endoperoxide receptor antagonist.
Topics: Adenosine Diphosphate; Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Binding, Competitive; Carbazoles; Cerebrovascular Disorders; Collagen; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Rats; Rats, Inbred SHR; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfonamides; Thromboembolism; Thromboxanes; Vasoconstriction | 1990 |
Arachidonic acid metabolites, ADP and thrombin modulate occlusive thrombus formation over extensive arterial injury in the rat.
Topics: Adenosine Diphosphate; Animals; Anticoagulants; Arachidonic Acid; Arachidonic Acids; Blood Coagulation; Blood Platelets; Carotid Artery Thrombosis; Electric Stimulation; Heparin; Male; Pentanoic Acids; Pyridines; Rats; Rats, Inbred Strains; Receptors, Prostaglandin; Receptors, Thromboxane; Thrombin; Thromboxane-A Synthase; Ticlopidine; Warfarin | 1990 |
Arginine vasopressin release from human platelets after irreversible aggregation.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Arginine Vasopressin; Blood Platelets; Collagen; Epinephrine; Female; Humans; Male; Platelet Aggregation; Thrombin | 1990 |
Inhibition of rabbit platelet aggregation by 1,4-naphthoquinones.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Calcium; Collagen; Naphthoquinones; Phosphatidylinositols; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Thrombin; Thromboxane A2 | 1990 |
A plasma inhibitor of platelet aggregation in patients with Argentine hemorrhagic fever.
Topics: Adenosine Diphosphate; Antibodies, Viral; Arachidonic Acid; Arachidonic Acids; Arenaviruses, New World; Calcimycin; Collagen; Hemorrhagic Fever, American; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Ristocetin; Temperature | 1990 |
Partial purification and characterization of phosphatidylinositol kinases from human platelets.
Topics: 1-Phosphatidylinositol 4-Kinase; Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Brain; Cattle; Cell Membrane; Chromatography; Cytosol; Humans; Hydrogen-Ion Concentration; Magnesium; Molecular Weight; Octoxynol; Phosphatidylserines; Phosphotransferases; Polyethylene Glycols; Potassium Chloride; Type C Phospholipases | 1990 |
Leukocyte and platelet function and eicosanoid production in subjects with hypercholesterolaemia.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Collagen; Fatty Acids; Female; Humans; Hyperlipoproteinemia Type II; Leukotriene B4; Lipids; Luminescent Measurements; Male; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Serotonin; Thromboxane B2 | 1990 |
Reversal of thromboxane A2/prostaglandin H2 and ADP-induced calcium release in intact platelets.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcium; Chlortetracycline; Cyclic AMP; Epoprostenol; Humans; Ion Channels; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Prostanoic Acids; Stimulation, Chemical; Thromboxane A2; Thromboxanes | 1985 |
Vasodilating agents and platelet function: intracellular free calcium concentration, cyclic nucleotides, and shape-change response.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Atrial Natriuretic Factor; Blood Platelets; Calcium; Cyclic AMP; Cyclic GMP; Humans; Pyridines; Quinazolines; Thrombin; Vasodilator Agents; Vasopressins | 1986 |
Comparison of inhibitory actions of prostacyclin and a new prostacyclin analogue on the aggregation of human platelet in whole blood.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Physiological Phenomena; Dose-Response Relationship, Drug; Epinephrine; Epoprostenol; Erythrocytes; Humans; Iloprost; Methods; Platelet Aggregation | 1987 |
Human rhabdosarcoma cell-induced aggregation of blood platelets.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Calcium; Epoprostenol; Humans; Platelet Aggregation; Rhabdomyosarcoma | 1989 |
Platelet aggregability in sleep-related stroke.
Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Arachidonic Acid; Arachidonic Acids; Cerebrovascular Disorders; Collagen; Epinephrine; Female; Humans; Male; Middle Aged; Platelet Aggregation; Sleep; Wakefulness | 1989 |
Iron chelators inhibit human platelet aggregation, thromboxane A2 synthesis and lipoxygenase activity.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Collagen; Deferiprone; Deferoxamine; Epinephrine; Humans; Iron; Iron Chelating Agents; Lipoxygenase; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Pyridones; Thromboxane A2 | 1989 |
[Platelet aggregation in asthma].
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Aspirin; Asthma; Bronchial Provocation Tests; Collagen; Drug Hypersensitivity; Epinephrine; Humans; Platelet Aggregation | 1989 |
Phase I study of Y-20811, a new long-acting thromboxane synthetase inhibitor by intravenous administration.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Body Temperature; Drug Evaluation; Half-Life; Humans; Imidazoles; Injections, Intravenous; Middle Aged; Pulse; Respiration; Thromboxane B2; Thromboxane-A Synthase | 1989 |
The relationship of insulin antibodies, platelet-fixing immune complexes and platelet-associated IgG to in vitro platelet aggregation and thromboxane B2 synthesis in childhood type 1 (insulin-dependent) diabetes mellitus.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Child; Collagen; Diabetes Mellitus, Type 1; Epinephrine; Female; Humans; Immunoglobulin G; Immunoglobulins; In Vitro Techniques; Insulin Antibodies; Male; Platelet Activating Factor; Platelet Aggregation; Reference Values; Thromboxane B2 | 1989 |
Potent antiplatelet effects of cyclic clofibric acid (CPIB) analogs on human platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Benzopyrans; Chromans; Clofibrate; Clofibric Acid; Epinephrine; Humans; Malondialdehyde; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Thrombin | 1989 |
[Effects of low-dose acetylsalicylic acid on thrombocytes in health subjects and in patients with coronary heart disease].
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Collagen; Coronary Disease; Dose-Response Relationship, Drug; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Thromboxane B2; Time Factors | 1989 |
Influence of strontium chloride on blood platelet function.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcium; Collagen; In Vitro Techniques; Nephelometry and Turbidimetry; Platelet Aggregation; Rabbits; Strontium; Thromboxane A2; Thromboxane B2; Thromboxanes | 1989 |
Inhibitory action of gliclazide on platelet functions.
Topics: Adenosine Diphosphate; Adult; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cell Adhesion; Endothelium, Vascular; Epoprostenol; Gliclazide; Humans; In Vitro Techniques; Kinetics; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Sulfonylurea Compounds | 1989 |
4-(1H-pyrazol-1-yl)-2-butylamine derivatives as inhibitors of blood platelet aggregation.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Butylamines; Chemical Phenomena; Chemistry; Collagen; Humans; In Vitro Techniques; Magnetic Resonance Spectroscopy; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrazoles; Structure-Activity Relationship | 1989 |
Platelet aggregation in whole blood--studies with a platelet counting technique--methodological aspects and some applications.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelet Disorders; Blood Preservation; Collagen; Fixatives; Formaldehyde; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count | 1989 |
[Kinetics of the cellular response: the phenomenon of supercooperativity in platelet aggregation].
Topics: Adenosine Diphosphate; Alprostadil; Arachidonic Acid; Arachidonic Acids; Epinephrine; Humans; In Vitro Techniques; Indomethacin; Kinetics; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors | 1989 |
Reduced sensitivity of human platelets to PAF-acether following ticlopidine intake.
Topics: Adenosine Diphosphate; Administration, Oral; Arachidonic Acid; Arachidonic Acids; Humans; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 1989 |
Agkistrodon piscivorus piscivorus platelet aggregation inhibitor: a potent inhibitor of platelet activation.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Crotalid Venoms; Humans; Molecular Sequence Data; Phospholipases; Phospholipases A; Platelet Activation; Platelet Aggregation Inhibitors; Protein Binding; Sequence Homology, Nucleic Acid; Thrombin | 1989 |
Blockade of ADP-induced Ca2+-signal and platelet aggregation by lipoxygenase inhibitors.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Calcium; Humans; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Masoprocol; Platelet Aggregation; Platelet Aggregation Inhibitors; Signal Transduction | 1989 |
Platelet aggregability during the first two years of type 1 (insulin-dependent) diabetes mellitus in children.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Child; Collagen; Diabetes Mellitus, Type 1; Female; Humans; Male; Platelet Aggregation; Prospective Studies; Reference Values | 1989 |
Effect of the concentration of Ca2+ in the suspending medium on the responses of human and rabbit platelets to aggregating agents.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Collagen; Dose-Response Relationship, Drug; Humans; Platelet Activating Factor; Platelet Aggregation; Rabbits; Thromboxane B2 | 1989 |
Novel inhibitory actions on platelet thromboxane and inositolphosphate formation by xanthones and their glycosides.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Collagen; Glycosides; Inositol Phosphates; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Structure-Activity Relationship; Thrombin; Thromboxanes; Xanthenes; Xanthones | 1989 |
The role of bradykinin on the effect of plasma kallikrein on platelet aggregation.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Collagen; Humans; Kallikreins; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombin | 1989 |
Increased platelet aggregation and intracellular calcium in hypertensive patients: effects of cyclo-oxygenase blockade.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Calcium; Cyclooxygenase Inhibitors; Female; Humans; Hypertension; Male; Middle Aged; Platelet Aggregation; Thromboxane A2 | 1989 |
Does acute experimental pancreatitis affect blood platelet function?
Topics: Acute Disease; Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; beta-Thromboglobulin; Blood Platelets; Dogs; Hemostasis; In Vitro Techniques; Pancreatitis; Platelet Activating Factor; Platelet Aggregation; Platelet Count; Thromboxane B2 | 1989 |
Novel peptides derived from a region of local homology between uteroglobin and lipocortin-1 inhibit platelet aggregation and secretion.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Annexins; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcium-Binding Proteins; Glycoproteins; Humans; Kinetics; Molecular Sequence Data; Oligopeptides; Phospholipases; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Uteroglobin | 1989 |
Kinins act on B1 or B2 receptors to release conjointly endothelium-derived relaxing factor and prostacyclin from bovine aortic endothelial cells.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Biological Factors; Cattle; Endothelium, Vascular; Epoprostenol; In Vitro Techniques; Kinins; Nitric Oxide; Rabbits; Receptors, Bradykinin; Receptors, Neurotransmitter | 1989 |
A permissive role of pertussis toxin substrate G-protein in P2-purinergic stimulation of phosphoinositide turnover and arachidonate release in FRTL-5 thyroid cells. Cooperative mechanism of signal transduction systems.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylate Cyclase Toxin; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Cell Line; Cyclic AMP; GTP-Binding Proteins; Guanosine Triphosphate; Pertussis Toxin; Phenylisopropyladenosine; Phosphatidylinositols; Rats; Receptors, Purinergic; Signal Transduction; Thyroid Gland; Thyrotropin; Virulence Factors, Bordetella; Xanthines | 1989 |
Receptor-operated calcium channels in human platelets.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcium; Calcium Channels; Collagen; Humans; Manganese; Platelet Activating Factor; Spectrometry, Fluorescence; Thrombin | 1989 |
Platelet aggregation in the Asian elephant is not dependent on thromboxane B2 production.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Collagen; Elephants; Female; Male; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Thromboxane B2; Verapamil | 1989 |
Antithrombotic effects of the thromboxane A2 antagonist, SQ 28,668, in vitro and in the coronary circulation in vivo.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Coronary Circulation; Cyclic AMP; Fibrinolytic Agents; Humans; In Vitro Techniques; Male; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Prostaglandin-Endoperoxide Synthases; Species Specificity; Swine; Thromboxane A2; Thromboxane-A Synthase | 1988 |
Inhibition of platelet aggregation by carbon monoxide is mediated by activation of guanylate cyclase.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Carbon Monoxide; Cyclic GMP; Enzyme Activation; Epinephrine; Epoprostenol; Guanylate Cyclase; Humans; In Vitro Techniques; Nitroprusside; Phospholipids; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Thromboxane B2 | 1987 |
Influence of some beta blockers (pindolol, atenolol, timolol and metoprolol) on aggregation and arachidonic acid metabolism in human platelets.
Topics: Adenosine Diphosphate; Adrenergic beta-Antagonists; Arachidonic Acid; Arachidonic Acids; Atenolol; Blood Platelets; Collagen; Epinephrine; Humans; Metoprolol; Phospholipids; Pindolol; Platelet Aggregation; Thromboxane B2; Timolol | 1987 |
Endothelium-dependent responses in autogenous femoral veins grafted into the arterial circulation of the dog.
Topics: Acetylcholine; Adenosine Diphosphate; Adrenergic alpha-Agonists; Animals; Arachidonic Acid; Arachidonic Acids; Arteries; Brimonidine Tartrate; Calcimycin; Dogs; Endothelium; Femoral Vein; Indomethacin; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Quinoxalines; Thrombin | 1987 |
Lymphocyte aggregation in response to adrenergic stimulation.
Topics: Adenosine Diphosphate; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Arachidonic Acid; Arachidonic Acids; Aspirin; Calcimycin; Cell Aggregation; Citrates; Citric Acid; Dyspnea; Female; Humans; Leukapheresis; Leukemia, Lymphoid; Lymphocytes; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Receptors, Adrenergic, beta | 1988 |
Phospholipase C from clostridium perfringens induces human platelet aggregation in plasma.
Topics: Adenosine Diphosphate; Adult; Apyrase; Arachidonic Acid; Arachidonic Acids; Aspirin; Clostridium perfringens; Female; Humans; In Vitro Techniques; Male; Platelet Aggregation; Type C Phospholipases | 1988 |
In vitro enhancement of human platelet aggregation by somatostatin.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Chromatography, Gel; Collagen; Drug Synergism; Epinephrine; Humans; Platelet Aggregation; Ristocetin; Somatostatin | 1988 |
Effects of atrial natriuretic factor on human platelet function.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Atrial Natriuretic Factor; Blood Platelets; Collagen; Epinephrine; Female; Humans; Male; Middle Aged; Platelet Aggregation; Thromboxane B2 | 1985 |
Platelet function in platelet concentrates and in whole blood.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Arachidonic Acid; Arachidonic Acids; beta-Thromboglobulin; Blood Platelets; Blood Preservation; Collagen; Humans; Platelet Aggregation; Platelet Transfusion; Time Factors | 1985 |
Synergistic effects of platelet-activating factor and other platelet agonists in human platelet aggregation and release: the role of ADP and products of the cyclooxygenase pathway.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; beta-Thromboglobulin; Blood Platelets; Calcimycin; Collagen; Drug Synergism; Epinephrine; Humans; Kinetics; Platelet Activating Factor; Platelet Aggregation; Ristocetin; Thrombin | 1985 |
Lack of antiplatelet activity of the new coumarin derivative 8-monochloro-3-beta-diethylaminoethyl-4-methyl-7-ethoxy- carboxylmethoxycoumarin under in vivo conditions in man.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; beta-Thromboglobulin; Blood Platelets; Chromonar; Collagen; Coumarins; Humans; In Vitro Techniques; Platelet Aggregation | 1986 |
Synthesis and platelet aggregation inhibitory activity of 10-oxa and 10-thia prostanoic acid derivatives.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Chemical Phenomena; Chemistry; Fatty Acids; Humans; In Vitro Techniques; Methods; Platelet Aggregation; Prostanoic Acids; Structure-Activity Relationship | 1987 |
Endogenous platelet-activating factor and anti-platelet-activating factor in patients with renovascular hypertension.
Topics: Adenosine Diphosphate; Adolescent; Adult; Angioplasty, Balloon; Arachidonic Acid; Arachidonic Acids; Female; Humans; Hypertension, Renovascular; Male; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Renal Veins | 1988 |
Synthesis and pharmacological evaluation of 5,6-exo-epoxy-7-oxabicyclo[2.2.1]heptane derivatives.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Chemical Phenomena; Chemistry; Epoxy Compounds; Fatty Acids, Monounsaturated; Guinea Pigs; Heptanes; Humans; In Vitro Techniques; Lung; Platelet Aggregation; Receptors, Prostaglandin; Receptors, Thromboxane; Structure-Activity Relationship | 1988 |
Zinc-induced platelet aggregation is mediated by the fibrinogen receptor and is not accompanied by release or by thromboxane synthesis.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Blood Platelet Disorders; Blood Platelets; Calcium; Collagen; Copper; Epoprostenol; Glycoproteins; Heparin; Humans; Manganese; Membrane Proteins; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Serotonin; Thromboxane A2; Thromboxanes; Zinc | 1985 |
Benzodiazepines inhibit human platelet activation: comparison of the mechanism of antiplatelet actions of flurazepam and diazepam.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Benzodiazepinones; Blood Platelets; Collagen; Cyclic AMP; Cyclic GMP; Diazepam; Epinephrine; Flumazenil; Flurazepam; Humans; Malondialdehyde; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Serotonin; Thrombin; Type C Phospholipases | 1985 |
Formamidine-mediated inhibition of rat platelet aggregation.
Topics: Adenosine Diphosphate; Amidines; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Chlorphenamidine; Collagen; Cyclic AMP; Male; Octopamine; Platelet Aggregation; Rats; Rats, Inbred Strains; Toluidines | 1985 |
Inhibitors of Na+/H+ exchange block stimulus-provoked arachidonic acid release in human platelets. Selective effects on platelet activation by epinephrine, ADP, and lower concentrations of thrombin.
Topics: Adenosine Diphosphate; Amiloride; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Carrier Proteins; Epinephrine; Humans; Hydrogen-Ion Concentration; Male; Platelet Aggregation; Serotonin; Sodium; Sodium-Hydrogen Exchangers; Thrombin; Thromboxanes | 1985 |
Aza-substituted omega-side-chain modifications of 7-oxabicyclo[2.2.1]heptane thromboxane A2 receptor antagonists: structure-activity relationships.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Bridged Bicyclo Compounds; Humans; Indicators and Reagents; Platelet Aggregation; Receptors, Cell Surface; Receptors, Prostaglandin; Receptors, Thromboxane; Structure-Activity Relationship; Thromboxane A2 | 1985 |
Disparate effects of the calcium-channel blockers, nifedipine and verapamil, on alpha 2-adrenergic receptors and thromboxane A2-induced aggregation of human platelets.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Chromatography, Gel; Collagen; Cyclic AMP; Drug Synergism; Epinephrine; Humans; Nifedipine; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Receptors, Adrenergic, alpha; Thromboxane A2; Tritium; Verapamil; Yohimbine | 1986 |
Influence of granulocyte elastase-like proteinase (ELP) on platelet functions.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Collagen; Cyclic AMP; Epinephrine; Granulocytes; Humans; Pancreatic Elastase; Platelet Aggregation; Ristocetin; Serotonin; Thrombin; Thromboxane A2 | 1986 |
Modification of platelet functions by monobromobimane, a fluorescent thiol group label.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Clot Retraction; Collagen; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Epinephrine; Fibrinogen; Fluorescent Dyes; Humans; Platelet Aggregation; Quaternary Ammonium Compounds; Sulfhydryl Compounds; Thrombin; Tritium | 1986 |
[Role of arachidonic acid and cAMP-dependent systems in thrombocyte aggregation induced by staphylococcal toxin and ADP].
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Bacterial Toxins; Cyclic AMP; In Vitro Techniques; Platelet Aggregation; Rabbits; Staphylococcus | 1986 |
Inhibitors of Na+/H+ exchange block epinephrine- and ADP-induced stimulation of human platelet phospholipase C by blockade of arachidonic acid release at a prior step.
Topics: Adenosine Diphosphate; Amiloride; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Carrier Proteins; Diglycerides; Enzyme Activation; Epinephrine; Humans; Inositol Phosphates; Kinetics; Male; Platelet Aggregation; Sodium-Hydrogen Exchangers; Tritium; Type C Phospholipases | 1986 |
Evidence that Na+/H+ exchange regulates receptor-mediated phospholipase A2 activation in human platelets.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Carrier Proteins; Chlortetracycline; Enzyme Activation; Epinephrine; Humans; Kinetics; Lysophospholipids; Methylamines; Phosphates; Phosphatidylinositols; Phospholipases; Phospholipases A; Phospholipases A2; Sodium-Hydrogen Exchangers | 1986 |
Platelet dysfunction in uremia. II. Correction by arachidonic acid of the impaired exposure of fibrinogen receptors by adenosine diphosphate or collagen.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Binding, Competitive; Blood Platelets; Collagen; Female; Fibrinogen; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Uremia | 1986 |
Critical evaluation of platelet aggregation in whole human blood.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Coagulation Tests; Collagen; Epoprostenol; Evaluation Studies as Topic; Humans; In Vitro Techniques; Platelet Aggregation; Ristocetin; Thrombin | 1986 |
Pathways responsible for platelet hypersensitivity in rats with diabetes. I. Streptozocin-induced diabetes.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Collagen; Creatine Kinase; Diabetes Mellitus; In Vitro Techniques; Male; Phosphocreatine; Platelet Adhesiveness; Platelet Aggregation; Rats; Rats, Inbred Strains; Serotonin; Thrombin | 1986 |
Pathways responsible for platelet hypersensitivity in rats with diabetes. II. Spontaneous diabetes in BB Wistar rats.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Glucose; Blood Platelets; Collagen; Creatine Kinase; Diabetes Mellitus; Phosphocreatine; Platelet Aggregation; Rats; Thrombin; Thromboxane B2 | 1986 |
Release of prostacyclin after erythrocyte adhesion to cultured vascular endothelium.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Adenosine Triphosphate; Adult; Anemia, Sickle Cell; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Blood Proteins; Blood Vessels; Cell Adhesion; Cells, Cultured; Cyclooxygenase Inhibitors; Diabetes Mellitus; Endothelium; Epoprostenol; Erythrocytes; Fibrinogen; Flurbiprofen; Humans; Leukocytes; Middle Aged; Plasma; Prostaglandins F; Thromboxane B2 | 1986 |
A defect of platelet release reaction in a patient with SLE: impaired platelet aggregation induced by phorbol ester with a normal phosphorylation of 40K protein.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Blood Proteins; Calcimycin; Collagen; Diglycerides; Epinephrine; Female; Humans; Lupus Erythematosus, Systemic; Phorbols; Phosphorylation; Platelet Activating Factor; Platelet Aggregation; Tetradecanoylphorbol Acetate; Thrombin | 1986 |
The roles of prostaglandin endoperoxides, thromboxane A2 and adenosine diphosphate in collagen-induced aggregation in man and the rat.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Collagen; Creatine Kinase; Dose-Response Relationship, Drug; Humans; Imidazoles; In Vitro Techniques; Male; Phosphocreatine; Platelet Aggregation; Prostaglandin Endoperoxides; Rats; Rats, Inbred Strains; Species Specificity; Thromboxane A2; Thromboxane B2 | 1986 |
FR-900452, a specific antagonist of platelet activating factor (PAF) produced by Streptomyces phaeofaciens. I. Taxonomy, fermentation, isolation, and physico-chemical and biological characteristics.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Chemical Phenomena; Chemistry; Collagen; Fermentation; Indoles; Piperazines; Platelet Activating Factor; Platelet Aggregation; Rabbits; Streptomyces | 1986 |
Synergistic platelet activation by aggregates of IgG and the phospholipid platelet-activating factor 1-O-alkyl-2-acetyl-SN-glycero-3-phosphorylcholine.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Dose-Response Relationship, Drug; Drug Synergism; Humans; Immunoglobulin G; Kinetics; Macromolecular Substances; Platelet Activating Factor; Platelet Aggregation; Serotonin | 1986 |
The in vitro effect of amrinone on platelet aggregation in human whole blood.
Topics: Adenosine Diphosphate; Aminopyridines; Amrinone; Arachidonic Acid; Arachidonic Acids; Collagen; Humans; In Vitro Techniques; Male; Platelet Aggregation; Thromboxane A2 | 1986 |
Inhibition of whole blood platelet aggregation by nicardipine, and synergism with prostacyclin in-vitro.
Topics: Adenosine Diphosphate; Antihypertensive Agents; Arachidonic Acid; Arachidonic Acids; Collagen; Drug Synergism; Epoprostenol; Female; Humans; Kinetics; Male; Nicardipine; Nifedipine; Platelet Aggregation; Reference Values; Thromboxane A2; Thromboxane B2 | 1986 |
Requirement of ADP for arachidonic acid-induced platelet aggregation: studies with selective thromboxane-synthase inhibitors.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Dinoprostone; Humans; Platelet Aggregation; Prostaglandins E; Serotonin; Thromboxane B2; Thromboxane-A Synthase | 1986 |
Osmotic stress as a factor in the detrimental effect of glycerol on human platelets.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cell Membrane Permeability; Glycerol; Humans; Osmotic Pressure; Platelet Aggregation; Platelet Count; Stress, Mechanical | 1986 |
Effects of high pressure on platelet aggregation in vitro.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Collagen; Decompression; Humans; Hydrogen-Ion Concentration; Hydrostatic Pressure; Platelet Aggregation; Pressure | 1986 |
Specific inhibition of PAF-acether-induced platelet activation by BN 52021 and comparison with the PAF-acether inhibitors kadsurenone and CV 3988.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Arachidonic Acid; Arachidonic Acids; Benzofurans; Benzopyrans; Blood Platelets; Diterpenes; Ginkgolides; Humans; In Vitro Techniques; Lactones; Lignans; Phospholipid Ethers; Plant Extracts; Platelet Activating Factor; Platelet Aggregation; Thiazoles | 1986 |
Relationship between structure and activity of aspirin-related compounds on the inhibition of in vitro platelet aggregation.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Aspirin; Collagen; Drug Interactions; Humans; In Vitro Techniques; Platelet Aggregation; Salicylates; Structure-Activity Relationship | 1986 |
Effects of acetylsalicylic acid on platelet aggregation in male and female whole blood: an in vitro study.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Aspirin; Collagen; Dose-Response Relationship, Drug; Epinephrine; Female; Humans; Male; Platelet Aggregation; Sex Factors | 1986 |
Platelet function in experimentally induced pancreatitis in the dog.
Topics: 6-Ketoprostaglandin F1 alpha; Acute Disease; Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Dinoprostone; Dogs; Fibrin Fibrinogen Degradation Products; Fluid Therapy; Hematocrit; Pancreatitis; Platelet Aggregation; Platelet Count; Prostaglandins; Prostaglandins E; Thromboxane B2 | 1986 |
Miconazole inhibition of platelet aggregation by inhibiting cyclooxygenase.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Collagen; Cyclooxygenase Inhibitors; Humans; Kinetics; Malondialdehyde; Miconazole; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases | 1986 |
Sex differences in mouse platelet aggregation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Dose-Response Relationship, Drug; Female; Hematocrit; Injections, Intravenous; Male; Mice; Mice, Inbred Strains; Platelet Aggregation; Platelet Count; Prostaglandin Endoperoxides, Synthetic; Sex Characteristics | 1986 |
Inhibition of human platelet aggregation and cytoplasmic calcium response by calcium antagonists: studies with aequorin and quin2.
Topics: Adenosine Diphosphate; Aequorin; Aminoquinolines; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Calcium; Calcium Channel Blockers; Culture Media; Cytoplasm; Diglycerides; Diltiazem; Epinephrine; Fluorescent Dyes; Humans; Luminescent Proteins; Nifedipine; Platelet Aggregation; Thrombin; Verapamil | 1986 |
[The suppressive effect of pyrrole-2-carboxylic acid on platelet aggregation].
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Collagen; Depression, Chemical; In Vitro Techniques; Male; Neoplasms, Experimental; Platelet Aggregation; Proline; Rabbits; Rats; Rats, Inbred Strains | 1986 |
Anti-thrombotic effect of KC-404, a novel cerebral vasodilator.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Cerebrovascular Disorders; Electroencephalography; Heart Block; Lauric Acids; Male; Mice; Mice, Inbred ICR; Pyridines; Rats; Rats, Inbred Strains; Thrombosis; Vasodilator Agents | 1986 |
Onion exerts antiaggregatory effects by altering arachidonic acid metabolism in platelets.
Topics: Adenosine Diphosphate; Allium; Arachidonic Acid; Arachidonic Acids; Calcimycin; Epinephrine; Humans; Phospholipases; Phospholipids; Plant Extracts; Platelet Aggregation; Thromboxane B2 | 1986 |
ATP-secretion occurs as an initial response in collagen induced platelet activation.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Collagen; Edetic Acid; Egtazic Acid; Humans; Kinetics; Platelet Aggregation; Theophylline; Verapamil; Yohimbine | 1986 |
Influence on platelet activity and red cell fluidity of epoprostenol and two stable prostacyclin analogues in vitro.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Epoprostenol; Erythrocytes; Humans; In Vitro Techniques; Platelet Aggregation | 1986 |
In vitro formation of activators for prostaglandin synthesis by neutrophils and macrophages from humans and guinea pigs.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Catalase; Enzyme Activation; Glutathione Peroxidase; Guinea Pigs; HEPES; Humans; Hydrogen Peroxide; Leukotrienes; Macrophages; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Tetradecanoylphorbol Acetate; Zymosan | 1986 |
Platelet aggregation and thromboxane release induced by arachidonic acid, collagen, ADP and platelet-activating factor following low dose acetylsalicylic acid in man.
Topics: Adenosine Diphosphate; Adolescent; Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Collagen; Dose-Response Relationship, Drug; Female; Humans; Male; Platelet Activating Factor; Platelet Aggregation; Thromboxane B2; Thromboxanes | 1986 |
Platelet aggregation in whole blood from patients with Glanzmann's thrombasthenia.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelet Disorders; Collagen; Epinephrine; Humans; In Vitro Techniques; Platelet Aggregation; Platelet Membrane Glycoproteins; Ristocetin; Thrombasthenia | 1987 |
Inhibitory effects of three new synthetic compounds on human platelet aggregation.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Humans; Kinetics; Platelet Activating Factor; Platelet Aggregation; Structure-Activity Relationship; Thiophenes; Thrombin | 1986 |
The influence of glutathione and other thiols on human platelet aggregation.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cell Membrane; Collagen; Cysteine; Dose-Response Relationship, Drug; Glutathione; Humans; Mercaptopurine; Platelet Aggregation; Sulfhydryl Compounds | 1986 |
Effects of benzydamine and other non-steroidal anti-inflammatory drugs on platelet aggregation induced by: arachidonic acid, ADP and collagen.
Topics: Adenosine Diphosphate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Benzydamine; Collagen; In Vitro Techniques; Male; Platelet Aggregation; Pyrazoles; Rabbits | 1986 |
Human platelet-tumor cell interactions vary with the tumor cell lines.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Alprostadil; Apyrase; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Breast Neoplasms; Carcinoma; Cell Line; Creatine Kinase; Humans; Neoplasm Metastasis; Platelet Aggregation; Thromboxane B2 | 1986 |
In vitro evidence of an endothelial cell-dependent antiplatelet activity for isosorbide dinitrate, but not for its 2- and 5-mononitrate metabolites.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Cell Extracts; Cells, Cultured; Dinoprostone; Endothelium; Female; Humans; Isosorbide Dinitrate; Male; Platelet Aggregation; Prostaglandins E; Thromboxane B2; Tissue Extracts | 1987 |
The role of phosphorylation/dephosphorylation reactions in the function of blood platelets.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Blood Vessels; Calcium; Cytoplasmic Granules; Diglycerides; Enzyme Activation; Humans; Membrane Proteins; Microscopy, Electron; Phosphorylation; Platelet Aggregation; Protein Kinase C; Pseudopodia | 1986 |
Platelet-activating factor (PAF-acether) induces high- and low-affinity binding of fibrinogen to human platelets via independent mechanisms.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Fibrinogen; Humans; Indomethacin; Kinetics; Macromolecular Substances; Platelet Activating Factor; Prostaglandin Endoperoxides; Protein Binding; Thromboxanes | 1986 |
Effect of phorbol 12-myristate 13-acetate (PMA) on agonist-induced arachidonate release and 5-hydroxytryptamine secretion in human platelets. Dependence of effects on agonist type and time of incubation with PMA.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Epinephrine; Humans; In Vitro Techniques; Kinetics; Male; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Serotonin; Tetradecanoylphorbol Acetate; Thrombin | 1987 |
Conformational responses of an arachidonate- and U46619-binding haemoprotein in relation to platelet activation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Carrier Proteins; Cattle; Cold Temperature; Hemeproteins; Immunodiffusion; Male; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Protein Conformation; Spectrophotometry | 1987 |
Amaurosis fugax under the age of 40 years.
Topics: Adenosine Diphosphate; Adolescent; Adult; Age Factors; Arachidonic Acid; Arachidonic Acids; Blindness; Child, Preschool; Female; Humans; Male; Platelet Aggregation | 1987 |
Effects of the lipid peroxidation product 4-hydroxynonenal on the aggregation of human platelets.
Topics: Adenosine Diphosphate; Aldehydes; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Drug Antagonism; Fatty Acids; Glutathione; Humans; In Vitro Techniques; Malondialdehyde; Platelet Activating Factor; Platelet Aggregation; Thrombin | 1987 |
[Platelet aggregation induced by arachidonic acid, ADP, thrombin. Study of the antiaggregation effects of verbenone and indomethacin].
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Bicyclic Monoterpenes; Humans; In Vitro Techniques; Indomethacin; Platelet Aggregation; Terpenes; Thrombin | 1986 |
Antiplatelet effect of butylidenephthalide.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Coagulation Factors; Calcimycin; Collagen; Dinoprostone; Guinea Pigs; Humans; In Vitro Techniques; Phthalic Acids; Phthalic Anhydrides; Platelet Activating Factor; Platelet Aggregation; Prostaglandins E; Rabbits; Thrombin; Thromboxane B2 | 1987 |
Tissue-type plasminogen activator and streptokinase induce platelet hyperaggregability in the rabbit.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Embolism; Evaluation Studies as Topic; Infusions, Intravenous; Male; Platelet Aggregation; Platelet Count; Rabbits; Streptokinase; Time Factors; Tissue Plasminogen Activator | 1987 |
Inhibition of rat platelet aggregation by a Prudhoe Bay crude oil and its aliphatic, aromatic, and heterocyclic fractions.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Epinephrine; Male; Petroleum; Platelet Aggregation; Rats; Thromboxane B2 | 1987 |
Effects of dietary supplementation with cod-liver oil on endothelium-dependent responses in porcine coronary arteries.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Cod Liver Oil; Coronary Vessels; Diet; Dinoprost; Endothelium, Vascular; Fish Oils; In Vitro Techniques; Indomethacin; Muscle Relaxation; Platelet Aggregation; Prostaglandins F; Serotonin; Swine; Thromboxane A2 | 1987 |
Coffee extracts inhibit platelet aggregation in vivo and in vitro.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Coffee; Collagen; Humans; Plant Extracts; Platelet Aggregation; Prostaglandins; Rabbits; Thromboxane B2 | 1987 |
Sphingosine inhibition of agonist-dependent secretion and activation of human platelets implies that protein kinase C is a necessary and common event of the signal transduction pathways.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Diglycerides; Humans; Kinetics; Phorbol 12,13-Dibutyrate; Phorbol Esters; Platelet Activating Factor; Platelet Aggregation; Protein Kinase C; Sphingosine; Thrombin | 1987 |
Platelet-activating factor in the inflammatory exudate in the anaphylactic phase of allergic inflammation in rats.
Topics: Adenosine Diphosphate; Anaphylaxis; Animals; Arachidonic Acid; Arachidonic Acids; Chromatography, High Pressure Liquid; Exudates and Transudates; Inflammation; Male; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Rats; Rats, Inbred Strains; Thiazoles | 1987 |
Platelet aggregation in homozygous beta thalassaemia.
Topics: Adenosine Diphosphate; Adolescent; Arachidonic Acid; Arachidonic Acids; Child; Child, Preschool; Collagen; Epinephrine; Female; Homozygote; Humans; Infant; Male; Platelet Aggregation; Thalassemia | 1987 |
Sex-related differences in platelet aggregation in native whole blood.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Collagen; Female; Fibrinogen; Humans; Male; Platelet Aggregation; Sex Factors; Thrombin | 1987 |
Ovine platelet function and its inhibition by T-2 toxin.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Female; Platelet Aggregation; Serotonin; Sesquiterpenes; Sheep; T-2 Toxin | 1987 |
Regulation of arachidonic acid-dependent Ca++ influx in human platelets.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcium; Glutathione; Humans | 1988 |
Effects of latamoxef on in vitro and ex vivo thromboxane A2 generation in human platelets.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cell Membrane; Humans; Moxalactam; Platelet Aggregation; Thromboxane A2 | 1988 |
Inherited bleeding disorders in the Eastern Province of Saudi Arabia.
Topics: Adenosine Diphosphate; Adolescent; Adult; Arachidonic Acid; Arachidonic Acids; Blood Coagulation Disorders; Blood Platelet Disorders; Child; Child, Preschool; Collagen; Consanguinity; Epinephrine; Female; Humans; Infant; Male; Platelet Aggregation; Ristocetin; Saudi Arabia | 1988 |
Synthetic aci-reductones: 3,4-dihydroxy-2H-1-benzopyran-2-ones and their cis- and trans-4a,5,6,7,8,8a-hexahydro diastereomers. Antiaggregatory, antilipidemic, and redox properties compared to those of the 4-substituted 2-hydroxytetronic acids.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Ascorbic Acid; Blood Platelets; Chemical Phenomena; Chemistry; Cholesterol; Coumarins; Humans; Hydrogen-Ion Concentration; Hypolipidemic Agents; Male; Oxidation-Reduction; Platelet Aggregation Inhibitors; Rats; Rats, Inbred Strains; Serotonin; Stereoisomerism; Structure-Activity Relationship; Triglycerides | 1988 |
Exchange of cyclooxygenase dependent metabolites between vessel wall and platelets in arterial thrombosis.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Epoprostenol; Imidazoles; Male; Mesenteric Arteries; Platelet Aggregation; Propionates; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains; Thrombosis; Thromboxane A2; Tranylcypromine | 1988 |
In vitro antiaggregant activity of paracetamol and derivatives.
Topics: Acetaminophen; Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Serotonin; Stereoisomerism; Structure-Activity Relationship; Thromboxane B2 | 1988 |
Combined arachidonic acid and ADP platelet inhibition maximizes patency of small-diameter vascular grafts.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Vessel Prosthesis; Carotid Arteries; Dogs; Femoral Artery; Platelet Aggregation; Polytetrafluoroethylene; Thromboxane B2; Ticlopidine; Vascular Patency | 1988 |
[Platelet aggregation induced by adenosine diphosphate, collagen and adrenaline in human platelet subpopulations].
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Epinephrine; Humans; Male; Platelet Aggregation | 1987 |
Platelet thromboxane formation capacity after ethanol withdrawal in chronic alcoholics.
Topics: Adenosine Diphosphate; Adult; Alcoholism; Arachidonic Acid; Arachidonic Acids; Bleeding Time; Blood Platelets; Collagen; Ethanol; Female; Fibrinogen; Humans; Liver Diseases, Alcoholic; Male; Middle Aged; Platelet Aggregation; Platelet Count; Serum Albumin; Substance Withdrawal Syndrome; Thromboxane B2 | 1988 |
Effects of ethanol on pathways of platelet aggregation in vitro.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Collagen; Ethanol; Humans; In Vitro Techniques; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Rabbits; Thrombin | 1988 |
Platelet aggregation is inhibited by long chain acyl-CoA.
Topics: Acyl Coenzyme A; Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Coenzyme A; Diglycerides; Dose-Response Relationship, Drug; Humans; Kinetics; Platelet Aggregation; Platelet Aggregation Inhibitors; Tetradecanoylphorbol Acetate; Thrombin | 1988 |
Human platelet electrorotation change induced by activation: inducer specificity and correlation to serotonin release.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Cell Membrane; Collagen; Cytoplasmic Granules; Electric Conductivity; Electrophysiology; Epinephrine; Humans; Kinetics; Microscopy, Electron; Platelet Activating Factor; Platelet Aggregation; Serotonin; Thrombin | 1988 |
Dose-response aggregometry in maternal/neonatal platelets.
Topics: Adenosine Diphosphate; Adolescent; Adult; Arachidonic Acid; Arachidonic Acids; Collagen; Dose-Response Relationship, Drug; Female; Humans; Infant, Newborn; Maternal-Fetal Exchange; Middle Aged; Platelet Aggregation; Pregnancy; Ristocetin | 1988 |
Effects of trifluoperazine on platelet activation.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Collagen; Epinephrine; Humans; Phospholipases A; Phospholipases A2; Platelet Aggregation; Protein Kinase C; Protein Kinase Inhibitors; Serotonin; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane B2; Trifluoperazine | 1985 |
Prostaglandins and human platelet aggregation. Implications for the anti-aggregating activity of thromboxane-synthase inhibitors.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Dinoprost; Dinoprostone; Drug Synergism; Humans; Imidazoles; Oxidoreductases; Platelet Aggregation; Prostaglandin D2; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandins; Prostaglandins D; Prostaglandins E; Prostaglandins F; Prostanoic Acids; Thromboxane B2; Thromboxane-A Synthase | 1985 |
Measurement of malonyldialdehyde production during sodium arachidonate-induced polymorphonuclear leukocyte aggregation.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Cell Aggregation; Dogs; Epinephrine; Imidazoles; In Vitro Techniques; Indomethacin; Malonates; Malondialdehyde; Neutrophils | 1985 |
Measurement by electrical impedance aggregometry of porcine platelets response to selected physiological agonists.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Cell Count; Blood Platelets; Collagen; Epinephrine; Female; Hematocrit; Humans; Male; Norepinephrine; Platelet Aggregation; Swine; Thrombin | 1985 |
Possible participation of adenosine 5'-diphosphate, arachidonic acid and paf-acether in the platelet pro-aggregating effect of uncontrolled insulin-dependent diabetic erythrocytes in vitro.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Diabetes Mellitus, Type 1; Erythrocytes; Glutaral; Humans; Plasma; Platelet Activating Factor; Platelet Aggregation | 1985 |
[Effect of bromhexine on microthrombosis in animal experiments].
Topics: Adenosine Diphosphate; Ambroxol; Animals; Arachidonic Acid; Arachidonic Acids; Bromhexine; Collagen; Disseminated Intravascular Coagulation; Humans; In Vitro Techniques; Lung; Platelet Aggregation; Pulmonary Embolism; Pulmonary Surfactants; Rabbits; Rats; Thrombosis | 1985 |
Platelet responsiveness and biosynthesis of thromboxane and prostacyclin in response to in vitro cocaine treatment.
Topics: Adenosine Diphosphate; Animals; Aorta, Abdominal; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcium; Cocaine; Collagen; Dose-Response Relationship, Drug; Epoprostenol; Male; Platelet Aggregation; Rabbits; Rats; Thromboxanes | 1985 |
Mechanism of anti-platelet aggregating action of dilazep.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Azepines; Blood Platelets; Carbon Radioisotopes; Collagen; Dilazep; Epinephrine; Humans; In Vitro Techniques; Nucleotides, Cyclic; Platelet Aggregation; Thromboxane B2 | 1985 |
The effects of amrinone on human platelet aggregation: evidence that amrinone does not act through a cyclic nucleotide mechanism in platelet rich plasma.
Topics: Adenosine Diphosphate; Aminopyridines; Amrinone; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Dose-Response Relationship, Drug; Humans; Nucleotides, Cyclic; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H | 1985 |
Thromboxane A2/prostaglandin H2 mobilizes calcium in human blood platelets.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcium; Chlortetracycline; Epoprostenol; Humans; Indomethacin; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Prostanoic Acids; Stimulation, Chemical; Thromboxane A2; Thromboxanes | 1985 |
Action mechanism of the platelet aggregation inducer and inhibitor from Echis carinatus snake venom.
Topics: Adenosine Diphosphate; Alprostadil; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Chymotrypsin; Collagen; Fibrinogen; Heparin; Hirudins; Platelet Activating Factor; Platelet Aggregation; Prostaglandins E; Rabbits; Thrombin; Viper Venoms | 1985 |
The tachyphylactic effect of arachidonic acid on in-vivo ADP induced arterial platelet thrombosis.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Coagulation; Drug Synergism; Rats; Thrombosis | 1985 |
Effect of latex-stimulated granulocytes on platelet aggregation in man.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Cell Communication; Collagen; Granulocytes; Hemostasis; Humans; In Vitro Techniques; Latex; Phagocytosis; Platelet Aggregation | 1985 |
Subcellular localization of vasopressin-like material in platelets.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Arginine Vasopressin; Blood Platelets; Calcimycin; Collagen; Epinephrine; Humans; Microscopy, Electron; Norepinephrine; Platelet Activating Factor; Subcellular Fractions | 1985 |
Long-term ultra-low-dose aspirin therapy and platelet function.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Bleeding Time; Collagen; Dose-Response Relationship, Drug; Epinephrine; Female; Humans; Male; Platelet Aggregation; Thromboxane B2; Thromboxanes; Time Factors | 1985 |
The effect of oral phenylbutazone on whole blood platelet aggregation in the dog.
Topics: Adenosine Diphosphate; Administration, Oral; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Dogs; Dose-Response Relationship, Drug; Male; Phenylbutazone; Platelet Aggregation | 1985 |
Platelet function during continuous insulin infusion treatment in insulin-dependent diabetic patients.
Topics: Adenosine Diphosphate; Adolescent; Adult; Arachidonic Acid; Arachidonic Acids; Blood Glucose; Blood Platelets; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Female; Humans; Insulin; Insulin Infusion Systems; Lipoproteins; Male; Middle Aged; Platelet Aggregation; Thromboxane A2; Thromboxane B2 | 1985 |
Ouabain inhibits endothelium-dependent relaxations to arachidonic acid in canine coronary arteries.
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Coronary Vessels; Dinoprost; Dogs; Endothelium; Female; Indomethacin; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Ouabain; Prostaglandins F; Thrombin; Time Factors; Vasodilation | 1985 |
Identification of platelet inhibitor present in the melon (Cucurbitacea cucumis melo).
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Collagen; Epinephrine; Fruit; Humans; Kinetics; Plant Extracts; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Thrombin | 1985 |
Effects of estradiol on platelet aggregation in mouse mesenteric arterioles and ex vivo.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Arterioles; Estradiol; Female; In Vitro Techniques; Male; Mesenteric Arteries; Mice; Mice, Inbred ICR; Platelet Aggregation; Sex Factors; Thromboembolism | 1985 |
Disaggregation and reaggregation of 'irreversibly' aggregated platelets: a method for more complete evaluation of anti-platelet drugs.
Topics: Adenosine Diphosphate; Adenylyl Cyclases; Adult; Antimalarials; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cell Membrane; Creatine Kinase; Cyclooxygenase Inhibitors; Drug Evaluation; Enzyme Activation; Epinephrine; Humans; Microscopy, Electron; Phosphocreatine; Phosphodiesterase Inhibitors; Platelet Aggregation | 1985 |
Platelet dysfunction in uremia. Multifaceted defect partially corrected by dialysis.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Blood Coagulation Disorders; Blood Platelets; Collagen; Epinephrine; Humans; Platelet Aggregation; Renal Dialysis; Thromboxane B2; Uremia | 1985 |
Vernolepin: an antiplatelet compound of natural origin.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Freezing; Glutaral; In Vitro Techniques; Microscopy, Electron; Platelet Aggregation; Rabbits; Sesquiterpenes; Time Factors | 1985 |
Inhibition of platelet aggregation by ketamine hydrochloride.
Topics: Adenosine Diphosphate; Anesthesia, General; Animals; Arachidonic Acid; Arachidonic Acids; Collagen; Depression, Chemical; Epinephrine; In Vitro Techniques; Ketamine; Male; Papio; Platelet Aggregation; Ristocetin; Thromboxane B2 | 1985 |
Inhibition of platelet aggregation by a factor from Flavobacterium heparinum.
Topics: Adenosine Diphosphate; Anticoagulants; Arachidonic Acid; Arachidonic Acids; Collagen; Depression, Chemical; Epinephrine; Flavobacterium; Humans; In Vitro Techniques; Platelet Aggregation; Ristocetin | 1985 |
Biological activity of platelet activating factor-amidophosphonate (PAF-AP), a novel phosphonolipid selective inhibitor of platelet activating factor (PAF).
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Collagen; Diglycerides; Epinephrine; Humans; Oxidation-Reduction; Phosphatidic Acids; Platelet Activating Factor; Platelet Aggregation; Thrombin | 1985 |
The effect of inhibition of endothelial cell cyclooxygenase on arterial thrombosis.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cyclooxygenase Inhibitors; Endothelium; Flurbiprofen; Indomethacin; Male; Mesenteric Arteries; Rats; Rats, Inbred Strains; Thrombosis | 1985 |
Platelet behaviour in normal pregnancy, pregnancy complicated by essential hypertension and pregnancy-induced hypertension.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Epinephrine; Female; Humans; Hypertension; Imidazoles; Platelet Aggregation; Pregnancy; Pregnancy Complications, Cardiovascular; Serotonin | 1985 |
Platelet aggregation in whole blood: the role of thromboxane A2 and adenosine diphosphate.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adenosine Diphosphate; Apyrase; Arachidonic Acid; Arachidonic Acids; Aspirin; Collagen; Cyclooxygenase Inhibitors; Epinephrine; Flurbiprofen; Humans; Imidazoles; In Vitro Techniques; Lipoxygenase Inhibitors; Platelet Aggregation; Pyrazoles; Thrombin; Thromboxane A2; Thromboxane-A Synthase | 1985 |
Platelet survival and function in rats with enhanced thrombotic tendency.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cell Survival; Collagen; Doxorubicin; Epoprostenol; In Vitro Techniques; Male; Platelet Aggregation; Rats; Thrombosis; Thromboxane B2 | 1985 |
Inhibition of platelet aggregation in whole blood by adrenoceptor antagonists.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Atenolol; Collagen; Drug Synergism; Epoprostenol; Humans; Labetalol; Pindolol; Platelet Aggregation; Propranolol; Solubility; Sympatholytics | 1985 |
Methionine-enkephalin does not alter human platelet aggregatory response.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Collagen; Enkephalin, Methionine; Epinephrine; Female; Humans; Male; Platelet Activating Factor; Platelet Aggregation; Thrombin | 1985 |
Butyltin compounds in vitro inhibition of human platelet epinephrine-induced aggregation and blockade of epinephrine binding to platelets.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Dihydroergotoxine; Dose-Response Relationship, Drug; Epinephrine; Humans; In Vitro Techniques; Male; Organotin Compounds; Platelet Aggregation; Tin; Tin Compounds; Trialkyltin Compounds | 1985 |
[Effect of heparin on platelet aggregation in vitro].
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Epinephrine; Heparin; Humans; Indomethacin; Platelet Aggregation; Ristocetin; Thrombin | 1984 |
Decrease of platelet aggregation and spreading via inhibition of the cAMP phosphodiesterase by trapidil.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cyclic AMP; Epoprostenol; Humans; Platelet Adhesiveness; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Pyrimidines; Theophylline; Thrombin; Trapidil | 1984 |
Alteration of platelet responses to metabolites of arachidonic acid by oral contraceptives.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adenosine Triphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Contraceptives, Oral; Contraceptives, Oral, Synthetic; Cyclic AMP; Epoprostenol; Female; Humans; Platelet Aggregation; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; Prostaglandins D; Thromboxane A2; Thromboxane B2 | 1984 |
Platelet secretion defect associated with impaired liberation of arachidonic acid and normal myosin light chain phosphorylation.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Child; Female; Humans; Male; Membrane Lipids; Middle Aged; Myosin-Light-Chain Phosphatase; Myosins; Phospholipids; Phosphoprotein Phosphatases; Phosphorylation; Platelet Aggregation; Serotonin; Thrombin | 1984 |
Effect of nabumetone (BRL 14777), a new anti-inflammatory drug, on human platelet reactivity ex vivo: comparison with naproxen.
Topics: Adenosine Diphosphate; Adult; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Epinephrine; Female; Humans; Male; Naproxen; Platelet Adhesiveness; Platelet Aggregation | 1982 |
ADP and arachidonic acid induced platelet aggregation in schizophrenia and atypical psychoses.
Topics: Adenosine Diphosphate; Antipsychotic Agents; Arachidonic Acid; Arachidonic Acids; Humans; Platelet Aggregation; Psychotic Disorders; Schizophrenia | 1984 |
Effects of dietary arachidonate deficiency on the aggregation of cat platelets.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Cats; Collagen; Dietary Fats; Epinephrine; Platelet Aggregation | 1984 |
Beta-adrenoceptor antagonists and human platelets: relationship of effects to lipid solubility.
Topics: Adenosine Diphosphate; Adrenergic beta-Antagonists; Alprostadil; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Collagen; Cyclic AMP; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Lipids; Platelet Aggregation; Propranolol; Prostaglandins E; Solubility; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1984 |
Platelet-activating factor-induced aggregation of human platelets specifically inhibited by triazolobenzodiazepines.
Topics: Adenosine Diphosphate; Alprazolam; Anti-Anxiety Agents; Arachidonic Acid; Arachidonic Acids; Benzodiazepines; Blood Platelets; Calcimycin; Chromatography, Gel; Collagen; Epinephrine; Humans; Platelet Activating Factor; Platelet Aggregation; Thrombin; Triazolam | 1984 |
In vitro investigation on the antiaggregating activity of ditazole.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Epinephrine; Humans; In Vitro Techniques; Oxazoles; Platelet Aggregation | 1984 |
Platelet impedance aggregation in whole blood and its inhibition by antiplatelet drugs.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Collagen; Electrodes; Epoprostenol; Hematocrit; Humans; Iloprost; Platelet Aggregation; Platelet Count; Plethysmography, Impedance | 1984 |
Platelet thromboxane synthesis and release reactions in myeloproliferative disorders.
Topics: Adenosine Diphosphate; Adult; Aged; Arachidonic Acid; Arachidonic Acids; beta-Thromboglobulin; Blood Platelets; Calcimycin; Collagen; Epinephrine; Female; Humans; Male; Middle Aged; Myeloproliferative Disorders; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Ristocetin; Serotonin; Thromboxane B2; Thromboxanes | 1982 |
Exposure of platelet fibrinogen-binding sites by collagen, arachidonic acid, and ADP: inhibition by a monoclonal antibody to the glycoprotein IIb-IIIa complex.
Topics: Adenosine Diphosphate; Antibodies, Monoclonal; Arachidonic Acid; Arachidonic Acids; Binding Sites; Blood Platelets; Collagen; Fibrinogen; Glycoproteins; L-Lactate Dehydrogenase; Platelet Aggregation; Platelet Membrane Glycoproteins; Thromboxane B2 | 1983 |
Novel 7-oxabicyclo[2.2.1]heptane prostacyclin agonists.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Epoprostenol; Humans; Platelet Aggregation; Prostaglandins; Prostaglandins, Synthetic; Structure-Activity Relationship | 1983 |
Effect of docosahexaenoic acid (DHA) on arachidonic acid metabolism and platelet function.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Binding Sites; Blood Platelets; Docosahexaenoic Acids; Epinephrine; Fatty Acids, Unsaturated; Humans; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Thrombin | 1983 |
Thrombin-induced platelet responses differ in requirement for receptor occupancy. Evidence for tight coupling of occupancy and compartmentalized phosphatidic acid formation.
Topics: Acetylglucosaminidase; Adenosine Diphosphate; Adenosine Triphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcium; Hirudins; Humans; Kinetics; Phosphatidic Acids; Platelet Aggregation; Receptors, Cell Surface; Receptors, Thrombin; Serotonin; Thrombin | 1981 |
9 alpha-homo-9,11-epoxy-5,13-prostadienoic acid analogues: specific stable agonist (SQ 26, 538) and antagonist (SQ 26, 536) of the human platelet thromboxane receptor.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cattle; Cyclic AMP; Fatty Acids, Monounsaturated; Fatty Acids, Unsaturated; Humans; Kinetics; Male; Platelet Aggregation; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Prostaglandins D; Receptors, Cell Surface; Receptors, Prostaglandin; Receptors, Thromboxane; Seminal Vesicles; Thromboxane-A Synthase | 1981 |
Arachidonate-induced fibrinogen binding to thrombin-degranulated rabbit platelets is independent of released ADP.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cytoplasmic Granules; Fibrin; Fibrinogen; Oligopeptides; Platelet Aggregation; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Thrombin | 1982 |
The inhibitory effects of exogenous arachidonic acid on rabbit platelet aggregation and the release reaction.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Cyclic AMP; Cytoplasmic Granules; Fibrinogen; Platelet Aggregation; Rabbits; Serotonin; Thrombin | 1982 |
Studies on aspirin derivatives with very little side effect. IV. Inhibitory effect of aspirin-isopropylantipyrine (AIA) on several experimental thromboses.
Topics: Adenosine Diphosphate; Adenylyl Cyclases; Animals; Antipyrine; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Cyclic AMP; Epoprostenol; Malondialdehyde; Muscle Contraction; Rats; Thrombosis | 1983 |
The effects of a mixed fish diet on platelet function, fatty acids and serum lipids.
Topics: Adenosine Diphosphate; Adult; Animals; Arachidonic Acid; Arachidonic Acids; Cholesterol; Collagen; Diet; Eicosapentaenoic Acid; Epinephrine; Fatty Acids; Fatty Acids, Unsaturated; Female; Fishes; Humans; Male; Platelet Aggregation; Triglycerides | 1983 |
Designing prostacyclin analogues.
Topics: Adenosine Diphosphate; Anesthesia; Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Cyclic AMP; Drug Stability; Epoprostenol; Horses; Humans; Hydroxyprostaglandin Dehydrogenases; In Vitro Techniques; Platelet Aggregation; Prostaglandins, Synthetic; Rats | 1983 |
Arachidonic acid-induced platelet aggregation is mediated by a thromboxane A2/prostaglandin H2 receptor interaction.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Arachidonic Acid; Arachidonic Acids; Drug Interactions; Humans; In Vitro Techniques; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Prostanoic Acids; Receptors, Cell Surface; Receptors, Prostaglandin; Receptors, Thromboxane; Thromboxane A2; Thromboxanes | 1984 |
Effects of dazoxiben and low-dose aspirin on platelet behaviour in man.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Epinephrine; Female; Humans; Imidazoles; Male; Oxidoreductases; Thromboxane-A Synthase | 1983 |
Impaired metabolism of arachidonate in selenium deficient animals.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Collagen; Diet; Male; Mice; Platelet Aggregation; Rats; Rats, Inbred Strains; Respiratory Insufficiency; Selenium | 1983 |
Platelet arachidonate metabolism and platelet function in zinc-deficient rats.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Bleeding Time; Blood Platelets; Male; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Inbred Strains; Thromboxane B2; Zinc | 1983 |
CV-3988 - a specific antagonist of platelet activating factor (PAF).
Topics: Adenosine Diphosphate; Alprostadil; Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Calcimycin; Collagen; Dose-Response Relationship, Drug; Male; Micelles; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Prostaglandins E; Rabbits; Rats; Rats, Inbred Strains; Thiazoles | 1983 |
In vivo platelet activation with in vitro hyperaggregability to arachidonic acid in renal allograft recipients.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Female; Graft Rejection; Humans; Kidney Transplantation; Male; Middle Aged; Platelet Aggregation; Platelet Factor 4; Platelet Function Tests; Serotonin; Time Factors | 1983 |
Inhibition of platelet aggregation by a new agent, 2,2'-dithiobis-(N-2-hydroxypropyl benzamide) (KF4939).
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Benzamides; Collagen; Dose-Response Relationship, Drug; Fibrinolytic Agents; Humans; In Vitro Techniques; Male; Mice; Papaverine; Platelet Aggregation; Rabbits; Rats; Rats, Inbred Strains; Thrombin; Thrombocytopenia; Thrombosis; Thromboxane A2 | 1983 |
Qualitative platelet defect in a case of heparin-induced thrombocytopenia.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Collagen; Epinephrine; Heparin; Humans; Male; Platelet Aggregation; Pulmonary Embolism; Thrombocytopenia | 1983 |
Stimulation of calcium uptake by 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine (platelet-activating factor) in rabbit platelets: possible involvement of the lipoxygenase pathway.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Biological Transport, Active; Blood Platelets; Calcium; Indomethacin; Platelet Activating Factor; Rabbits; Verapamil | 1983 |
The role of ADP secretion and thromboxane synthesis in factor VIII binding to platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Apyrase; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Collagen; Factor VIII; Humans; Prostaglandin Endoperoxides, Synthetic; Thrombin; Thromboxane A2; Thromboxanes | 1983 |
Lipoxygenase inhibitors alter aggregation and adhesiveness of human blood platelets from aspirin-treated patients.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Aspirin; Catechols; Collagen; Humans; Lipoxygenase Inhibitors; Masoprocol; Platelet Adhesiveness; Platelet Aggregation | 1983 |
Some properties of mouse platelets.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Collagen; Epoprostenol; Indomethacin; Lipoxygenase; Male; Mice; Mice, Inbred ICR; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases | 1983 |
[Role of arachidonic acid in platelet aggregation induced by S. typhimurium endotoxin].
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Drug Synergism; Endotoxins; Humans; Platelet Aggregation; Salmonella typhimurium; Stimulation, Chemical | 1983 |
Modulation of equine platelet function by diethylcarbamazine (DEC).
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Collagen; Depression, Chemical; Diethylcarbamazine; Horses; Platelet Aggregation; Serotonin; Thrombin | 1983 |
Platelet function abnormalities in response to arachidonic acid in the acute phase of myocardial infarction.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Female; Humans; In Vitro Techniques; Male; Myocardial Infarction; Platelet Aggregation; Thromboxane B2; Time Factors | 1983 |
Adhesion and aggregation of thrombin prestimulated human platelets on surface-bound fibrinogen: evidence for involvement of ADP and arachidonic acid pathways.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Coagulation; Fibrinogen; Glass; Humans; In Vitro Techniques; Platelet Adhesiveness; Platelet Aggregation; Serotonin; Surface Properties; Thrombin | 1983 |
Arachidonic acid induced platelet aggregation and thromboxane formation is inhibited by OKY-1581.
Topics: 6-Ketoprostaglandin F1 alpha; Acrylates; Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Dinoprost; Dinoprostone; Humans; In Vitro Techniques; Male; Methacrylates; Platelet Aggregation; Prostaglandins E; Prostaglandins F; Thromboxane B2; Thromboxanes | 1983 |
Effects of garlic extract and of three pure components isolated from it on human platelet aggregation, arachidonate metabolism, release reaction and platelet ultrastructure.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cell Membrane; Collagen; Epinephrine; Garlic; Humans; Plant Extracts; Plants, Medicinal; Platelet Aggregation | 1983 |
Aggregation of platelets from monocrotaline pyrrole-treated rats.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Collagen; Hypertension, Pulmonary; Male; Monocrotaline; Platelet Aggregation; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Time Factors | 1983 |
[Inhibiting action of anti-arrhythmia agents of the phenothiazine series--etmozin and its diethylamino analog--on platelet aggregation and metabolism of endogenous arachidonic acid].
Topics: Adenosine Diphosphate; Anti-Arrhythmia Agents; Arachidonic Acid; Arachidonic Acids; Calcimycin; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Malondialdehyde; Moricizine; Phenothiazines; Platelet Aggregation | 1984 |
Fluorescence anisotropy changes in platelet membranes during activation.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cell Membrane; Fluorescence Polarization; Humans; Lipid Bilayers; Microscopy, Fluorescence; Platelet Aggregation; Thrombin | 1984 |
Platelet activation studied by fluorescence polarization.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Colchicine; Fluorescence Polarization; Humans; Molecular Weight; Platelet Aggregation; Sulfhydryl Reagents; Thrombin | 1984 |
Acquisition and aggregation of canine blood platelets: basic mechanisms of function and differences because of breed origin.
Topics: Adenosine Diphosphate; Anesthesia; Anesthetics; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Blood Specimen Collection; Collagen; Dogs; Humans; Platelet Aggregation; Platelet Count; Serotonin; Species Specificity; Thiamylal | 1984 |
Time-dependent inhibition of platelet aggregation by dopamine and 3-methoxytyramine. Important roles of their metabolites.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Dopamine; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Platelet Aggregation; Time Factors | 1984 |
Increased sensitivity of arachidonic acid-induced platelet aggregation in the presence of carbon dioxide.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Carbon Dioxide; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Inflammation; Platelet Aggregation | 1984 |
Inhibition of prostanoid-mediated platelet aggregation in vivo and in vitro by 3-hydroxymethyl-dibenzo(b,f)thiepin 5,5-dioxide (L-640,035).
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Collagen; Dibenzothiepins; Electric Stimulation; Female; Guinea Pigs; Humans; Male; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Rabbits; Thrombosis; Thromboxane A2; Thromboxane B2; Thromboxanes | 1984 |
Platelet alterations in shear flow: dose response of prostacyclin on human platelets.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Blood Viscosity; Epoprostenol; Female; Humans; Kinetics; Male; Platelet Aggregation; Platelet Factor 4; Stress, Mechanical; Surface Properties | 1983 |
Relationships between the chemical constitution of aggregation inhibitors and human blood platelet response profile.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Aspirin; Calcimycin; Calcium; Calcium Channel Blockers; Carbamates; Chlorpromazine; Gallic Acid; Humans; In Vitro Techniques; Piperidines; Platelet Aggregation; Propranolol; Thrombin | 1984 |
Effects of aqueous extracts of onion, garlic and ginger on platelet aggregation and metabolism of arachidonic acid in the blood vascular system: in vitro study.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Collagen; Condiments; Dinoprost; Epinephrine; Humans; Plants, Edible; Platelet Aggregation; Prostaglandins F; Prostaglandins G; Prostaglandins H; Rats; Thromboxane B2 | 1984 |
Inhibition of platelet ADP and serotonin release by carbon monoxide and in cigarette smokers.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Carbon Monoxide; Epinephrine; Humans; Nicotiana; Plants, Toxic; Platelet Aggregation; Serotonin; Smoking | 1984 |
Inhibition of platelet function by injectable isosorbide dinitrate.
Topics: Adenosine Diphosphate; Adult; Angina Pectoris; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Epinephrine; Female; Heart Rate; Humans; In Vitro Techniques; Infusions, Parenteral; Isosorbide Dinitrate; Male; Middle Aged; Platelet Aggregation; Thromboxane B2 | 1984 |
Receptor and non receptor-mediated activation of blood platelets. Effect on membrane-cytoskeleton interaction.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Cell Membrane; Cyanogen Bromide; Cytoskeleton; Electrophoresis; In Vitro Techniques; Lectins; Membrane Proteins; Protein Binding; Thrombin; Wheat Germ Agglutinins | 1984 |
Arachidonate metabolism, 5-hydroxytryptamine release and aggregation in human platelets activated by palmitaldehyde acetal phosphatidic acid.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Chlorpromazine; Humans; In Vitro Techniques; Indomethacin; Lipids; Malondialdehyde; Platelet Aggregation; Platelet Count; Quinacrine; Serotonin; Thionucleotides; Thrombin | 1984 |
A major role of ADP in thromboxane transfer experiments: studies in patients with platelet secretion defects.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cytoplasmic Granules; Humans; In Vitro Techniques; Platelet Aggregation; Serotonin; Thromboxane A2; Thromboxanes | 1984 |
Effects of tris on responses of human and rabbit platelets to aggregating agents.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Calcimycin; Calcium; Collagen; Dose-Response Relationship, Drug; Humans; Platelet Activating Factor; Platelet Aggregation; Rabbits; Serotonin; Thrombin; Tromethamine | 1984 |
A functional study of platelets in menstrual fluid.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Female; Humans; Menstruation; Platelet Aggregation; Time Factors; Veins | 1984 |
Evidence for the involvement of arachidonic acid metabolites in spontaneous and drug-induced contractions of rat urinary bladder.
Topics: Adenosine Diphosphate; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Aspirin; Diet; Fatty Acids, Essential; Hexamethonium Compounds; Indomethacin; Ketoprofen; Male; Muscle Contraction; Physostigmine; Piroxicam; Rats; Rats, Inbred Strains; Tetrodotoxin; Thiazines; Urinary Bladder | 1984 |
Near-normal glycaemic control does not correct abnormal platelet reactivity in diabetes mellitus.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Blood Glucose; Blood Platelets; Collagen; Diabetes Mellitus, Type 1; Female; Humans; Insulin Infusion Systems; Male; Middle Aged; Platelet Aggregation; Thromboxane B2 | 1984 |
Haemostatic mechanisms of the newborn foal: reduced platelet responsiveness.
Topics: Adenosine Diphosphate; Animals; Animals, Newborn; Arachidonic Acid; Arachidonic Acids; Blood Coagulation; Collagen; Epinephrine; Horses; Partial Thromboplastin Time; Platelet Aggregation; Platelet Count; Prothrombin Time; Serotonin; Thrombin | 1984 |
Activity of prostaglandin biosynthetic pathways in rat pancreatic islets.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Epoprostenol; Islets of Langerhans; Male; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins; Prostaglandins H; Rabbits; Rats; Rats, Inbred Strains; Time Factors | 1984 |
The effect of alpha, alpha'-bis[3-(N,N-diethylcarbamoyl)piperidino]-p-xylene on human blood platelet structural physiology.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcium; Cell Membrane; Collagen; Epinephrine; Humans; Microscopy, Electron; Nipecotic Acids; Platelet Aggregation | 1984 |
[Quantitative method of measuring platelet ATP released in vitro in the presence of various aggregating agents].
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Humans; In Vitro Techniques; Platelet Aggregation | 1984 |
Influence of fenflumizole on platelet aggregation in man.
Topics: Adenosine Diphosphate; Adult; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Bleeding Time; Blood Coagulation; Collagen; Fibrinolysis; Humans; Imidazoles; Male; Middle Aged; Platelet Aggregation | 1984 |
Pregnancy induces increased platelet responsiveness in the non-human primate.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Cercopithecidae; Drug Synergism; Epinephrine; Erythrocebus patas; Female; In Vitro Techniques; Platelet Aggregation; Pregnancy; Pregnancy, Animal | 1984 |
XC 386: a new antiplatelet agent.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Collagen; Kinetics; Malondialdehyde; Platelet Aggregation; Pyrazoles; Rats; Rats, Inbred Strains; Thrombin; Thromboxane B2 | 1984 |
Influence of verapamil and diltiazem on aggregatory responses in cat and rabbit platelet rich plasma.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Benzazepines; Calcium Channel Blockers; Cats; Diltiazem; Female; In Vitro Techniques; Male; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Rabbits; Verapamil | 1984 |
Aqueous extracts of onion, garlic and ginger inhibit platelet aggregation and alter arachidonic acid metabolism.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Epinephrine; Garlic; Humans; Plant Extracts; Plants, Medicinal; Platelet Aggregation; Prostaglandins | 1984 |
Effect of prostacyclin (epoprostenol) on the aggregation of human platelets in whole blood in vitro.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Epoprostenol; Female; Humans; Male; Platelet Aggregation; Platelet Count; Thrombin; Time Factors | 1984 |
The effect of urethane and thiopental sodium on platelet aggregation in vitro and in vivo.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Collagen; In Vitro Techniques; Male; Platelet Aggregation; Platelet Count; Rats; Rats, Inbred Strains; Thiopental; Urethane | 1984 |
Effect of fatty acid saturation on NADPH-dependent lipid peroxidation in rat liver microsomes.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Chlorides; Dietary Fats; Fatty Acids; Ferric Compounds; Lipid Peroxides; Malondialdehyde; Microsomes, Liver; NADP; Phosphatidylcholines; Rats | 1981 |
Platelet adherence to collagen: role of prostaglandin-thromboxane synthesis.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Calcium; Collagen; Dose-Response Relationship, Drug; Humans; Imidazoles; Indomethacin; Magnesium; Middle Aged; Platelet Adhesiveness; Prostaglandins; Serotonin; Temperature; Thromboxanes | 1981 |
Comparative study on the prostacyclin producing activities in bovine heart valves.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Carbon Radioisotopes; Cattle; Endocardium; Epoprostenol; Heart Valves; Leukotrienes; Lipid Peroxides; Myocardium; Peroxides; Platelet Aggregation; Prostaglandins; Prostaglandins H; Tissue Extracts | 1981 |
Acceleration of endogeneous PGI2 generation from isolated rat aortae by MK-447.
Topics: Adenosine Diphosphate; Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Butylated Hydroxytoluene; Collagen; Epoprostenol; Indomethacin; Male; Muscle, Smooth, Vascular; Platelet Aggregation; Prostaglandins; Rats; Rats, Inbred Strains | 1981 |
Platelet antiaggregant activity of plafibride ex vivo in rat, dog and rabbit.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Clofibrate; Clofibric Acid; Collagen; Dogs; Epinephrine; Female; In Vitro Techniques; Male; Platelet Aggregation; Rabbits; Rats; Rats, Inbred Strains; Species Specificity | 1981 |
Lithium stimulates thromboxane B2 formation in human platelets.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Dinoprost; Dinoprostone; Humans; Lithium; Platelet Aggregation; Prostaglandins E; Prostaglandins F; Rabbits; Sodium; Thromboxane B2; Thromboxanes | 1981 |
Aggregation and thromboxane B2 formation in platelets and vascular prostacyclin production from genetically obese rats.
Topics: Adenosine Diphosphate; Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Epoprostenol; Obesity; Platelet Aggregation; Prostaglandins; Rats; Rats, Zucker; Thromboxane B2; Thromboxanes | 1981 |
Modulation of Platelet thromboxane A2 and arterial prostacyclin by dietary vitamin E.
Topics: Adenosine Diphosphate; Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Epoprostenol; Male; Prostaglandins; Rats; Rats, Inbred Strains; Thromboxane A2; Thromboxanes; Vitamin E; Vitamin E Deficiency | 1981 |
Thromboxane A2 and the endoperoxides mediate canine platelet activation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Dogs; Dose-Response Relationship, Drug; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandins E; Prostaglandins F; Thromboxane A2; Thromboxane B2; Thromboxanes | 1981 |
Effects of methylprednisolone and hydrocortisone on aggregation of rabbit platelets induced by arachidonic acid and other aggregating substances.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Collagen; Female; Hydrocortisone; Male; Methylprednisolone; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Prostaglandins H; Rabbits | 1981 |
Stored human platelets retain full aggregation potential in response to pairs of aggregating agents.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Arachidonic Acid; Arachidonic Acids; Blood Preservation; Citrates; Collagen; Drug Synergism; Epinephrine; Glucose; Humans; Platelet Aggregation; Thromboxane B2; Time Factors | 1982 |
Cultured megakaryocytes: changes in the cytoskeleton after ADP-induced spreading.
Topics: Actinin; Actins; Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Contractile Proteins; Cytoskeleton; Filamins; Guinea Pigs; Megakaryocytes; Microfilament Proteins; Microtubules; Myosins; Thrombin; Tubulin | 1982 |
Inhibition of platelet thromboxane synthesis by 7-(1-imidazolyl) heptanoic acid: dissociation from inhibition of aggregation.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Drug Synergism; Female; Humans; Imidazoles; Indomethacin; Male; Platelet Aggregation; Thromboxane B2; Thromboxanes; Time Factors | 1981 |
Effect of acute zinc deprivation on plasma zinc and platelet aggregation in adult males.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Body Weight; Circadian Rhythm; Humans; Male; Nitrogen; Platelet Aggregation; Zinc | 1982 |
Increased platelet activity after termination of prostacyclin infusion into man.
Topics: Adenosine Diphosphate; Adult; Aged; Arachidonic Acid; Arachidonic Acids; Arteriosclerosis Obliterans; Blood Platelets; Collagen; Epoprostenol; Female; Humans; Middle Aged; Platelet Aggregation; Prostaglandins; Thromboangiitis Obliterans; Thromboxane A2 | 1981 |
Anti-aggregatory actions of calcium channel blockers in cat platelets.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Calcium Channel Blockers; Cats; In Vitro Techniques; Male; Platelet Aggregation | 1982 |
Inhibition by sulphinpyrazone of the platelet-dependent bronchoconstriction due to platelet-activating factor (PAF-acether) in the guinea pig.
Topics: Adenosine Diphosphate; Airway Resistance; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Bronchi; Guinea Pigs; In Vitro Techniques; Lysophosphatidylcholines; Muscle Contraction; Platelet Activating Factor; Platelet Count; Sulfinpyrazone | 1982 |
Reevaluation of sex differences in platelet aggregation in a physiologic system.
Topics: Adenosine Diphosphate; Adult; Aging; Arachidonic Acid; Arachidonic Acids; Aspirin; Collagen; Female; Humans; Infant, Newborn; Male; Platelet Aggregation; Sex Factors | 1981 |
The effect of arachidonic acid on the aggregability of human platelet rich plasma.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Humans; Male; Platelet Aggregation; Time Factors | 1982 |
Gastric vascular actions of prostanoids and the dual effect of arachidonic acid.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Dogs; Female; Indomethacin; Male; Norepinephrine; Perfusion; Platelet Aggregation; Prostaglandins; Serotonin; Stomach; Vasoconstriction; Vasodilation | 1982 |
Platelet aggregation: inhibition of secondary aggregation by phenol.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Humans; In Vitro Techniques; Male; Phenol; Phenols; Phospholipids; Platelet Aggregation; Temperature; Time Factors | 1982 |
A platelet phospholipase inhibitor from the medicinal herb feverfew (Tanacetum parthenium).
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Fatty Acids, Unsaturated; Humans; Hydroxy Acids; In Vitro Techniques; Magnoliopsida; Phospholipases; Plant Extracts; Plants, Medicinal; Sesquiterpenes; Tanacetum parthenium; Thrombin; Thromboxane B2 | 1982 |
Relationship between platelet aggregation, thromboxane synthesis and albumin concentration in nephrotic syndrome.
Topics: Adenosine Diphosphate; Adolescent; Adult; Aged; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cholesterol; Collagen; Female; Humans; Male; Middle Aged; Nephrotic Syndrome; Platelet Aggregation; Serum Albumin; Thromboxane B2; Thromboxanes; Triglycerides | 1982 |
Effects of vinblastine on malondialdehyde formation, serotonin release and aggregation in human platelets.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Humans; In Vitro Techniques; Malonates; Malondialdehyde; Microsomes; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Serotonin; Thrombin; Vinblastine | 1982 |
The use of prostacyclin in the separation from plasma and washing of human platelets.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Cell Separation; Collagen; Dose-Response Relationship, Drug; Epinephrine; Epoprostenol; Female; Fibrinogen; Humans; Indomethacin; Male; Platelet Aggregation; Plateletpheresis; Prostaglandins; Time Factors | 1982 |
Aggregation and thromboxane formation by platelets and vascular prostacyclin production from BB rats. An animal model for type I diabetes.
Topics: Adenosine Diphosphate; Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Diabetes Mellitus, Experimental; Epoprostenol; Platelet Aggregation; Prostaglandins; Rats; Rats, Inbred Strains; Thromboxane B2; Thromboxanes | 1982 |
Purinergic vs peptidergic stimulation of lipolysis and prostaglandin generation in the perfused rabbit kidney.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Angiotensin II; Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; In Vitro Techniques; Kidney; Lipolysis; Male; Peptides; Prostaglandins; Purines; Rabbits | 1982 |
The facilitating effects of adrenaline on platelet aggregation.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Aspirin; Drug Synergism; Epinephrine; Humans; Platelet Aggregation; Radioimmunoassay; Thromboxane B2 | 1982 |
Structure-activity studies of aspirin and related compounds on platelet aggregation, arachidonic acid metabolism in platelets and artery, and arterial prostacyclin activity.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Aspirin; Benzoates; Dinoprostone; Platelet Aggregation; Prostaglandins E; Rabbits; Rats; Structure-Activity Relationship | 1982 |
Opposite effect of lysine on platelet aggregation induced by arachidonate and by other aggregants.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Collagen; Dose-Response Relationship, Drug; Drug Synergism; Humans; Lysine; Male; Malondialdehyde; Platelet Aggregation; Rats; Rats, Inbred Strains; Ristocetin; Serotonin | 1982 |
Effect of acetylsalicylic acid on platelet aggregation and thromboxane B2 production in flowing aortic blood in the rat studied with a filter loop technique.
Topics: Adenosine Diphosphate; Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Aspirin; Male; Methods; Platelet Aggregation; Rats; Rats, Inbred Strains; Salicylates; Thromboxane B2; Thromboxanes | 1982 |
Relaxin inhibits prostacyclin release by the rat pregnant myometrium.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Epoprostenol; Female; Kinetics; Myometrium; Oxytocin; Platelet Aggregation; Pregnancy; Pregnancy, Animal; Prostaglandins; Rats; Rats, Inbred Strains; Relaxin; Swine; Uterus | 1982 |
Platelet activating factor (PAF) causes human platelet aggregation through the mechanism of membrane modulation.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Cell Membrane; Epinephrine; Epoprostenol; Humans; Platelet Activating Factor; Platelet Aggregation; Thromboxane B2; Time Factors | 1982 |
Platelet-mediated vascular contractions: inhibition of the serotonergic component by ketanserin.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Depression, Chemical; Ketanserin; Male; Muscle Contraction; Muscle, Smooth, Vascular; Piperidines; Rats; Rats, Inbred Strains; Serotonin Antagonists; Suprofen; Thrombin | 1982 |
Platelet aggregation measured in rabbit whole blood: in vitro study of 3 aggregating agents and ex vivo inhibition by aspirin and ticlopidine.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Collagen; In Vitro Techniques; Platelet Aggregation; Platelet Count; Rabbits; Thiophenes; Ticlopidine | 1982 |
Effects of N-acetylglucosamine and platelet inhibitors on the synergistic interaction of platelets and aggregating agents in the presence of wheat germ agglutinin.
Topics: Acetylglucosamine; Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Collagen; Drug Synergism; Epinephrine; Glucosamine; Humans; Kinetics; Lectins; Platelet Aggregation; Serotonin; Wheat Germ Agglutinins | 1982 |
Platelet aggregation in whole blood determined using the Ultra-Flo 100 Platelet Counter.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Specimen Collection; Collagen; Humans; Platelet Aggregation; Platelet Count | 1982 |
The metabolism of arachidonic acid to an antiaggregatory compound in isolated lungs of fetal and neonatal rabbits.
Topics: Adenosine Diphosphate; Animals; Animals, Newborn; Arachidonic Acid; Arachidonic Acids; Drug Stability; Epoprostenol; Indomethacin; Lung; Platelet Aggregation; Rabbits | 1982 |
[Synthesis and antiplatelet activity of 2-amino-4,5-diphenylthiazole derivatives].
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Cells, Cultured; Collagen; Cyclooxygenase Inhibitors; Platelet Aggregation Inhibitors; Rabbits; Structure-Activity Relationship; Thiazoles | 1995 |
Inhibition of platelet aggregation in whole blood by alcohol.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Collagen; Depression, Chemical; Ethanol; Female; Hemolysis; Humans; Male; Phospholipases; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Wistar | 1995 |
Indapamide inhibits human platelet aggregation in vitro: comparison with hydrochlorothiazide.
Topics: Adenosine Diphosphate; Arachidonic Acid; Blood Proteins; Calcium; Collagen; Dose-Response Relationship, Drug; Humans; Hydrochlorothiazide; In Vitro Techniques; Indapamide; Myosins; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Radioimmunoassay; Serotonin; Thrombin; Thromboxane B2 | 1993 |
Thrombin-receptor agonist peptides, in contrast to thrombin itself, are not full agonists for activation and signal transduction in human platelets in the absence of platelet-derived secondary mediators.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Arachidonic Acid; Aspirin; Blood Platelets; Cytoskeleton; Drug Interactions; GTP-Binding Proteins; Hirudins; Humans; Integrin alpha2; Membrane Glycoproteins; Molecular Sequence Data; Phosphatidylinositols; Phospholipases A; Phospholipases A2; Phosphorylation; Platelet Activation; Platelet Aggregation; Proto-Oncogene Proteins pp60(c-src); Purinergic P2 Receptor Antagonists; Receptors, Thrombin; Signal Transduction; Thrombin | 1994 |
The effect of streptozocin-induced diabetes on platelet aggregation as determined by impedance aggregometry and platelet secretion: a possible role for nitric oxide.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Blood Platelets; Collagen; Diabetes Mellitus, Experimental; Male; Nitric Oxide; Platelet Aggregation; Rats; Rats, Wistar | 1995 |
Platelet aggregability in patients with a VVI pacemaker.
Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; beta-Thromboglobulin; Collagen; Epinephrine; Female; Humans; Male; Pacemaker, Artificial; Platelet Aggregation; Platelet Factor 4 | 1993 |
Antiplatelet actions of 2-(4-[1-(2-chlorophenyl) piperazinyl]) methyl-2,3-dihydroimidazo[1,2-c]quinazolin-5(6H)-one compound.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Blood Platelets; Calcium; Collagen; Cyclic AMP; Epinephrine; Fibrinogen; Humans; Imidazoles; Pancreatic Elastase; Phosphatidylinositols; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Quinazolines; Rabbits; Receptors, Cell Surface; Signal Transduction; Thromboxane A2; Thromboxane B2 | 1995 |
Whole-blood platelet aggregation predicts in vitro and in vivo primary hemostatic function in the elderly.
Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Aging; Arachidonic Acid; Arteries; Bleeding Time; Collagen; Endothelium, Vascular; Factor VIIa; Female; Fibrinogen; Hemostasis; Humans; Male; Multivariate Analysis; Platelet Aggregation; Sex Characteristics | 1995 |
Studies on in vitro effect of picotamide on human platelet aggregation in platelet-rich plasma and whole blood.
Topics: Adenosine Diphosphate; Adult; Analysis of Variance; Arachidonic Acid; Collagen; Humans; In Vitro Techniques; Male; Phthalic Acids; Platelet Aggregation; Platelet Aggregation Inhibitors; Thromboxane B2; Thromboxanes | 1995 |
Platelet activation induced by interleukin-6: evidence for a mechanism involving arachidonic acid metabolism.
Topics: Adenosine Diphosphate; Arachidonic Acid; beta-Thromboglobulin; Blood Platelets; Calcimycin; Cytoskeleton; Drug Synergism; Humans; Imidazoles; Indomethacin; Interleukin-6; Platelet Activation; Prostaglandin-Endoperoxide Synthases; Recombinant Proteins; Thromboxane B2 | 1994 |
The effects of aspirin and paracetamol on the aggregation of equine blood platelets.
Topics: Acetaminophen; Adenosine Diphosphate; Animals; Arachidonic Acid; Aspirin; Blood Platelets; Cell Size; Collagen; Dose-Response Relationship, Drug; Horses; In Vitro Techniques; Nephelometry and Turbidimetry; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Thromboxane A2 | 1994 |
N,N,N-trimethylsphingosine modifies aggregatory response and ATP release from platelets in whole blood.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adolescent; Adult; Arachidonic Acid; Blood Platelets; Collagen; Humans; Platelet Aggregation; Protein Kinase C; Ristocetin; Sphingosine; Tetradecanoylphorbol Acetate | 1994 |
Factor XIIIa binding to activated platelets is mediated through activation of glycoprotein IIb-IIIa.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Antibodies, Monoclonal; Antigens, CD; Arachidonic Acid; Blood Platelets; Calcimycin; Collagen; Epinephrine; Fibrinogen; Fibronectins; Flow Cytometry; Humans; In Vitro Techniques; Kinetics; Membrane Glycoproteins; Membrane Proteins; Oligopeptides; Platelet Activation; Platelet Membrane Glycoproteins; Reference Values; Tetradecanoylphorbol Acetate; Thrombasthenia; Thrombin; Thrombospondins; Time Factors; Transglutaminases | 1994 |
Antiplatelet effects of clausine-D isolated from Clausena excavata.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alkaloids; Animals; Arachidonic Acid; Carbazoles; Collagen; Epinephrine; Phosphatidylinositols; Plant Extracts; Platelet Aggregation Inhibitors; Prostaglandin D2; Rabbits; Thromboxane B2 | 1994 |
Development of aspirin resistance in persons with previous ischemic stroke.
Topics: Adenosine Diphosphate; Arachidonic Acid; Aspirin; Blood Platelets; Brain Ischemia; Cerebrovascular Disorders; Cohort Studies; Collagen; Dose-Response Relationship, Drug; Drug Resistance; Drug Tolerance; Epinephrine; Female; Follow-Up Studies; Humans; Intracranial Embolism and Thrombosis; Male; Platelet Aggregation; Recurrence | 1994 |
Daily variations of platelet aggregation in relation to blood and plasma serotonin in diabetes.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Circadian Rhythm; Collagen; Diabetes Mellitus, Type 2; Epinephrine; Female; Humans; Male; Middle Aged; Platelet Aggregation; Serotonin | 1994 |
Effect of picotamide on the calcium mobilization and phospholipase C activation in human platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Arachidonic Acid; Aspirin; Blood Platelets; Calcium; Chromatography, Gel; Enzyme Activation; Humans; In Vitro Techniques; Phthalic Acids; Platelet Activation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Receptors, Thromboxane; Thrombin; Thromboxane A2; Type C Phospholipases | 1994 |
New pyrazolylhydrazone derivatives as inhibitors of platelet aggregation.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Collagen; Dimethyl Sulfoxide; Hydrazones; Indomethacin; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrazoles; Rabbits; Structure-Activity Relationship | 1993 |
Effect of single oral dose of aspirin on human platelet functions and plasma plasminogen activator inhibitor-1.
Topics: Adenosine Diphosphate; Arachidonic Acid; Aspirin; Blood Platelets; Epinephrine; Female; Fibrinogen; Humans; In Vitro Techniques; Male; Plasminogen Activator Inhibitor 1; Platelet Aggregation; Time Factors | 1993 |
Triterpenes and B-sitosterol from piper betle: isolation, antiplatelet and anti-inflammatory effects.
Topics: Adenosine Diphosphate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Areca; Aspirin; Chromatography, Liquid; Edema; Humans; Plants, Medicinal; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Sitosterols; Triterpenes | 1993 |
Inhibition of platelet thromboxane formation and phosphoinositides breakdown by diisoeugenol.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Blood Platelets; Collagen; Cyclic AMP; Eugenol; Humans; Membrane Lipids; Phosphatidylinositols; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Thrombin; Thromboxanes | 1994 |
Inhibition of collagen-induced platelet aggregation and adhesion by a pseudocyanide derivative of avicine isolated from Zanthoxylum integrifoliolum Merr.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Blood Platelets; Calcium; Cell Adhesion; Collagen; Dioxoles; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Inositol Phosphates; Phenanthridines; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prostaglandin D2; Proteoglycans; Rabbits; Structure-Activity Relationship; Thromboxane B2 | 1993 |
Influence of heat on platelet biochemistry, structure, and function.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adult; Animals; Aorta; Arachidonic Acid; Blood Platelets; Blood Proteins; Calcium; Collagen; Cytoskeleton; Endothelium, Vascular; Epinephrine; Hot Temperature; Humans; In Vitro Techniques; Kinetics; Microscopy, Electron; Muscle, Smooth, Vascular; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Rabbits; Serotonin; Thrombin; Time Factors | 1993 |
Prevention of experimental carotid artery thrombosis by applaggin.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Blood Platelets; Carotid Artery Thrombosis; Crotalid Venoms; Disease Models, Animal; Dogs; Kinetics; Male; Platelet Activation; Platelet Aggregation Inhibitors | 1993 |
Anti-platelet and anti-thrombotic effects of OP-41483.alpha-CD, a prostacyclin analogue, in experimental animals.
Topics: Adenosine Diphosphate; alpha-Cyclodextrins; Animals; Arachidonic Acid; Blood Coagulation Factors; Blood Platelets; Blood Pressure; Collagen; Cyclodextrins; Dogs; Epoprostenol; Female; Fibrinolytic Agents; Humans; Macaca; Male; Platelet Activating Factor; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Rabbits; Rats; Rats, Wistar; Species Specificity; Thrombocytopenia | 1993 |
Thrombus formation and platelet-vessel wall interaction in the nephrotic syndrome under flow conditions.
Topics: Adenosine Diphosphate; Adolescent; Adult; Angiotensin III; Arachidonic Acid; Biopsy; Blood Coagulation Factors; Blood Platelets; Collagen; Endothelium, Vascular; Erythrocyte Deformability; Extracellular Matrix; Female; Fibrin; Fibrinogen; Humans; In Vitro Techniques; Kidney; Male; Microscopy, Electron, Scanning; Middle Aged; Muscle, Smooth, Vascular; Nephrotic Syndrome; Platelet Adhesiveness; Platelet Aggregation; Thrombosis; Umbilical Arteries | 1994 |
Effect of high concentration perflubron emulsion on platelet function.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Blood Platelets; Calcimycin; Calcium; Emulsions; Fluorocarbons; Humans; Hydrocarbons, Brominated; Platelet Aggregation Inhibitors; Swine | 1993 |
Aggregation of killer whale platelets.
Topics: Adaptation, Physiological; Adenosine Diphosphate; Animals; Arachidonic Acid; Blood Platelets; Calcimycin; Collagen; Dolphins; Epinephrine; Female; Male; Platelet Activating Factor; Platelet Aggregation; Ristocetin; Thromboxane B2; Time Factors | 1993 |
Cocaine-induced platelet defects.
Topics: Adenosine Diphosphate; Arachidonic Acid; Calcium; Cocaine; Collagen; Hematologic Diseases; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors | 1993 |
Whole blood platelet aggregation in moderate and severe pre-eclampsia.
Topics: Adenosine Diphosphate; Arachidonic Acid; Collagen; Epinephrine; Female; Humans; Platelet Activating Factor; Platelet Aggregation; Postpartum Period; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, Third | 1993 |
gamma-Pyrone compounds. IV: Synthesis and antiplatelet effects of mono- and dioxygenated xanthones and xanthonoxypropanolamine.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; In Vitro Techniques; Platelet Aggregation; Platelet Aggregation Inhibitors; Propanolamines; Rabbits; Xanthenes | 1993 |
An increase in phosphatidic acid in the absence of changes in diacylglycerol in human platelets stimulated with ADP.
Topics: Adenosine Diphosphate; Arachidonic Acid; Blood Platelets; Diglycerides; Humans; In Vitro Techniques; Phosphatidic Acids; Platelet Aggregation; Thrombin; Thromboxane A2; Tritium | 1993 |
Effect of KBT-3022, a new diphenylthiazole derivative, on platelet functions.
Topics: Adenosine Diphosphate; Administration, Oral; Animals; Arachidonic Acid; Aspirin; Blood Platelets; Collagen; Edema; Erythema; Gastric Mucosa; Guinea Pigs; Humans; Mice; Platelet Aggregation Inhibitors; Pyrroles; Rabbits; Rats; Serotonin; Species Specificity; Thiazoles; Thrombin; Ultraviolet Rays | 1995 |
Role of platelet-endothelial cell adhesion molecule (PECAM) in platelet adhesion/aggregation over injured but not denuded endothelium in vivo and ex vivo.
Topics: Adenosine Diphosphate; Animals; Antibodies, Monoclonal; Antigens, Differentiation, Myelomonocytic; Arachidonic Acid; Cell Adhesion Molecules; Collagen; Endothelium, Vascular; In Vitro Techniques; Mice; Platelet Adhesiveness; Platelet Aggregation; Platelet Endothelial Cell Adhesion Molecule-1 | 1996 |
Platelet aggregation and peripheral serotonergic system in kidney transplant recipients treated with cyclosporine.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Azathioprine; Biological Transport; Collagen; Cyclosporine; Drug Therapy, Combination; Humans; Immunosuppressive Agents; In Vitro Techniques; Kidney Transplantation; Middle Aged; Platelet Aggregation; Prednisolone; Reference Values; Ristocetin; Serotonin | 1996 |
Local amplification of platelet function by 8-Epi prostaglandin F2alpha is not mediated by thromboxane receptor isoforms.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Arachidonic Acid; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Cell Line; Collagen; Dinoprost; F2-Isoprostanes; Fatty Acids, Unsaturated; Humans; In Vitro Techniques; Inositol Phosphates; Kidney; Kinetics; Pertussis Toxin; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Radioligand Assay; Receptors, Thromboxane; Recombinant Proteins; Thrombin; Thromboxane A2; Transfection; Virulence Factors, Bordetella | 1996 |
Effect of pyridoxal-5'-phosphate on aggregation of platelets from stored human concentrates induced by arachidonic acid.
Topics: Adenosine Diphosphate; Arachidonic Acid; Blood Platelets; Blood Specimen Collection; Calcimycin; Humans; In Vitro Techniques; Kinetics; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Thrombin | 1996 |
Platelet-neutrophil interaction and superoxide anion generation: involvement of purine nucleotides.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Analysis of Variance; Arachidonic Acid; Blood Platelets; Calcimycin; Humans; In Vitro Techniques; Kinetics; Neutrophils; Superoxides | 1996 |
Effects of storage on in vitro platelet responses: comparison of ACD and Na citrate anticoagulated samples.
Topics: Adenosine Diphosphate; Adult; Anticoagulants; Arachidonic Acid; Blood Platelets; Blood Preservation; Cell Survival; Citrates; Citric Acid; Collagen; Epinephrine; Female; Glucose; Humans; Male; Platelet Aggregation; Platelet Count | 1996 |
Flow cytometric evaluation of the effect of various thrombin inhibitors on platelet activation in whole blood.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Arachidonic Acid; Collagen; Enzyme Inhibitors; Evaluation Studies as Topic; Flow Cytometry; Humans; Molecular Sequence Data; Platelet Activation; Recombinant Proteins; Reference Values; Thrombin; Thromboplastin | 1996 |
Dose-responses to inducers and inhibitors of platelet aggregation analysed via a micro-method.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Collagen; Cricetinae; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Oligopeptides; Peptides, Cyclic; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Platelet Function Tests; Rabbits; Scattering, Radiation; Thiazolidines | 1996 |
Platelet aggregation, sensitivity to prostaglandin E1 and thromboxane A2 release in recombinant hirudin- and heparin-anticoagulated blood.
Topics: Adenosine Diphosphate; Adult; Alprostadil; Arachidonic Acid; Female; Gas Chromatography-Mass Spectrometry; Heparin; Hirudins; Humans; Male; Platelet Aggregation; Recombinant Proteins; Thromboxane A2 | 1996 |
The efficacy and potency of antiplatelet activity of ticlopidine is increased by aspirin.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Aspirin; Collagen; Drug Synergism; Female; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 1996 |
Hemostasis, platelet function and serotonin in acute and chronic renal failure.
Topics: Acute Kidney Injury; Adenosine Diphosphate; Adolescent; Adult; Aged; alpha-2-Antiplasmin; Antithrombin III; Arachidonic Acid; Blood Platelets; Collagen; Female; Fibrinolysin; Fibrinolysis; Fibronectins; Hemostasis; Humans; Kidney Failure, Chronic; Lipoprotein(a); Male; Middle Aged; Peptide Fragments; Peptide Hydrolases; Plasminogen Activator Inhibitor 1; Platelet Aggregation; Prothrombin; Renal Dialysis; Ristocetin; Serotonin; Tissue Plasminogen Activator; von Willebrand Factor | 1996 |
Erythropoietin and uremic platelet aggregation in vivo and in vitro.
Topics: Adenosine Diphosphate; Adult; Aged; Anemia; Arachidonic Acid; Case-Control Studies; Collagen; Erythropoietin; Hemostasis; Humans; In Vitro Techniques; Middle Aged; Platelet Aggregation; Recombinant Proteins; Renal Dialysis; Ristocetin; Uremia | 1996 |
Critical evaluation of the quantification of ATP release reaction in whole blood.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Arachidonic Acid; Collagen; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Pancytopenia; Thrombocytopenia | 1996 |
Phospholipase A2: a potentially important determinant of adenosine triphosphate levels during hypoxic-reoxygenation tubular injury.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Calcium; Cytochalasin D; Hydrogen Peroxide; In Vitro Techniques; Kidney Tubules, Proximal; Male; Mice; Mice, Inbred Strains; Nucleic Acid Synthesis Inhibitors; Oxidative Stress; Oxygen Consumption; Phospholipases A; Phospholipases A2; Reperfusion Injury; Sodium-Potassium-Exchanging ATPase | 1996 |
Effects of azathioprine and mizoribine on aggregation of normal and uremic platelets.
Topics: Adenosine Diphosphate; Arachidonic Acid; Azathioprine; Collagen; Humans; Immunosuppressive Agents; In Vitro Techniques; Kidney Failure, Chronic; Platelet Aggregation; Reference Values; Renal Dialysis; Ribonucleosides; Ristocetin; Serotonin; Uremia | 1996 |
Sevoflurane inhibits human platelet aggregation and thromboxane A2 formation, possibly by suppression of cyclooxygenase activity.
Topics: Adenosine Diphosphate; Anesthetics, Inhalation; Arachidonic Acid; Binding Sites; Drug Interactions; Epinephrine; Ethers; Halothane; Humans; Isoflurane; Methyl Ethers; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Radioimmunoassay; Sevoflurane; Thromboxane A2; Thromboxane B2 | 1996 |
In vitro effect of avarone and avarol, a quinone/hydroquinone couple of marine origin, on platelet aggregation.
Topics: Adenosine Diphosphate; Antineoplastic Agents; Arachidonic Acid; Blood Platelets; Cyclohexenes; Humans; Platelet Aggregation Inhibitors; Sesquiterpenes; Thromboxane B2 | 1996 |
Antithrombotic effect in vivo of thrombotic substances adsorbed on a platinum surface.
Topics: Adenosine Diphosphate; Adsorption; Albumins; Animals; Arachidonic Acid; Biocompatible Materials; Catheterization; Collagen; Female; Fibrinogen; Male; Platelet Activation; Platinum; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Surface Properties; Thrombin; Thrombosis; Venae Cavae | 1996 |
New chiral inhibitors of induced platelet aggregation: the enantiomeric specificity of (R)- and (S)-methyl and ethyl esters of 1-(4-[(1-hydroxycarbonyl)-ethoxy]-benzyl)-1H-1,2,3-triazole as a tool for determining their biological target.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Stereoisomerism; Triazoles | 1996 |
In vitro platelet function in controlled ovarian hyperstimulation cycles.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adult; Arachidonic Acid; Blood Platelets; Collagen; Estradiol; Female; Fertilization in Vitro; Humans; Ovulation Induction; Platelet Aggregation; von Willebrand Factor | 1997 |
Increased platelet aggregation due to chilling to 20 degrees C is not related to increased sensitivity to agonists.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Analysis of Variance; Arachidonic Acid; Blood Platelets; Cold Temperature; Humans; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Thromboxane A2; Thromboxane B2; Vasoconstrictor Agents | 1997 |
Antiplatelet effects of some aporphine and phenanthrene alkaloids in rabbits and man.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Aporphines; Arachidonic Acid; Blood Platelets; Collagen; Cyclic AMP; Guaiacol; Humans; Isoquinolines; Isotope Labeling; Lipoxygenase Inhibitors; Male; Phenanthrenes; Platelet Activating Factor; Platelet Aggregation Inhibitors; Quinolines; Rabbits; Radioimmunoassay; Structure-Activity Relationship; Thrombin; Thromboxane B2; Vasoconstrictor Agents | 1997 |
Diversity of agonist-mediated signal transduction pathways in human platelets.
Topics: Adenosine Diphosphate; Androstadienes; Arachidonic Acid; Blood Platelets; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Epinephrine; Humans; Phosphoinositide-3 Kinase Inhibitors; Platelet Activating Factor; Platelet Aggregation; Serotonin; Signal Transduction; Wortmannin | 1997 |
Anti-thrombotic and anti-inflammatory activities of protopine.
Topics: Adenosine Diphosphate; Alkaloids; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Benzophenanthridines; Berberine Alkaloids; Blood Platelets; Carrageenan; Edema; Fibrinolytic Agents; Histamine H1 Antagonists; Male; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Rabbits; Rats; Rats, Sprague-Dawley; Thromboxane A2 | 1997 |
Altered circadian rhythm of platelet aggregation in hemodialyzed patients.
Topics: Adenosine Diphosphate; Arachidonic Acid; Circadian Rhythm; Collagen; Female; Humans; Male; Middle Aged; Platelet Aggregation; Renal Dialysis; Serotonin; Uremia | 1997 |
Arachidonic acid inhibits uptake of amino acids and potentiates PKC effects on glutamate, but not GABA, exocytosis in isolated hippocampal nerve terminals.
Topics: 4-Aminopyridine; Adenosine Diphosphate; Adenosine Triphosphate; Amino Acids; Animals; Arachidonic Acid; Aspartic Acid; Biological Transport; Exocytosis; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Indomethacin; Kinetics; L-Lactate Dehydrogenase; Male; Masoprocol; Nerve Endings; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Wistar; Sodium; Synaptosomes | 1997 |
Increased platelet sensitivity to ADP in mice lacking platelet-type 12-lipoxygenase.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Adenosine Diphosphate; Animals; Arachidonate 12-Lipoxygenase; Arachidonic Acid; Blood Platelets; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Gene Targeting; Mice; Mice, Mutant Strains; Platelet Aggregation; Second Messenger Systems; Thromboembolism | 1998 |
Impaired cytosolic calcium mobilization and aggregation in response to collagen in platelets from Japanese black cattle with Chediak-Higashi syndrome.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Blood Platelets; Calcium; Cattle; Cattle Diseases; Chediak-Higashi Syndrome; Collagen; Cytosol; In Vitro Techniques; Indomethacin; Japan; Platelet Aggregation; Reference Values | 1998 |
[In vitro study of the effects of various 4-hydroxyisophthalic acid derivatives on human platelet aggregation].
Topics: Adenosine Diphosphate; Arachidonic Acid; Epinephrine; Humans; Molecular Structure; Phthalic Acids; Platelet Aggregation; Platelet Aggregation Inhibitors; Structure-Activity Relationship | 1983 |
Anti-platelet aggregation constituents from Formosan Toddalia asiatica.
Topics: Adenosine Diphosphate; Alkaloids; Arachidonic Acid; Benzoquinones; Blood Platelets; Collagen; Coumarins; Humans; Molecular Structure; Plant Extracts; Plant Stems; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Taiwan; Thrombin | 1998 |
Inhibition of platelet aggregation by a protein factor present in rat peripheral polymorphonuclear leukocyte supernatant.
Topics: Adenosine Deaminase; Adenosine Diphosphate; Animals; Arachidonic Acid; Calcimycin; Cells, Cultured; Culture Media, Conditioned; Macaca mulatta; Male; Methylene Blue; Neutrophils; Platelet Aggregation; Platelet Aggregation Inhibitors; Proteins; Rats; Rats, Sprague-Dawley; Serine Proteinase Inhibitors; Temperature; Time Factors | 1998 |
Pharmacologic activation of the human coronary microcirculation in vitro: endothelium-dependent dilation and differential responses to acetylcholine.
Topics: Acetylcholine; Adenosine Diphosphate; Adolescent; Adult; Aged; Aged, 80 and over; Arachidonic Acid; Bradykinin; Calcimycin; Child; Child, Preschool; Coronary Circulation; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Heart Atria; Heart Ventricles; Humans; In Vitro Techniques; Infant; Infant, Newborn; Ionophores; Male; Microcirculation; Middle Aged; Stimulation, Chemical; Substance P; Vasoconstriction; Vasodilator Agents | 1998 |
Platelet agonists enhance the import of phosphatidylethanolamine into human platelets.
Topics: Adenosine Diphosphate; Apolipoproteins B; Arachidonic Acid; Arginine; Biological Transport; Blood Coagulation; Blood Platelets; Collagen; Dansyl Compounds; Hirudins; Humans; Lipoproteins, LDL; Peptide Fragments; Phosphatidylethanolamines; Phospholipids; Platelet Activation; Protein Kinase C | 1998 |
Soluble saccharides block the inhibition of agonist-induced human platelet aggregation observed after in vitro incubation of human platelet-rich plasma with porcine aortic endothelial cells.
Topics: Adenosine Diphosphate; Animals; Aorta, Thoracic; Arachidonic Acid; Blood Platelets; Cells, Cultured; Collagen; Endothelium, Vascular; Hexoses; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Solubility; Swine; Time Factors; Umbilical Veins | 1998 |
Effects of chroman derivatives on platelet aggregation induced by some aggregating agents in rabbits.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Chromans; Collagen; Male; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Structure-Activity Relationship | 1998 |
Inhibition of platelet activation by the Alzheimer's disease amyloid precursor protein.
Topics: Adenosine Diphosphate; Alzheimer Disease; Amyloid beta-Protein Precursor; Arachidonic Acid; Cell Culture Techniques; Dinoprostone; Dose-Response Relationship, Drug; Epinephrine; Humans; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Recombinant Proteins; Structure-Activity Relationship; Thrombin; Thromboxane B2 | 1998 |
Coagulation defects and altered hemodynamic responses in mice lacking receptors for thromboxane A2.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Arachidonic Acid; Bleeding Time; Blood Coagulation Disorders; Collagen; Female; Hemodynamics; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptors, Thromboxane; Shock; Thromboxane A2 | 1998 |
Correlation between the in vivo efficacy of GPIIb/IIIa receptor antagonists (m7E3, MK-383 and DMP-728) and ex vivo platelet inhibition.
Topics: Adenosine Diphosphate; Animals; Antibodies, Monoclonal; Arachidonic Acid; Bleeding Time; Blood Flow Velocity; Blood Platelets; Carotid Arteries; Carotid Artery Thrombosis; Citrates; Dogs; Dose-Response Relationship, Drug; Female; Heparin; Immunoglobulin Fab Fragments; Male; Mesylates; Mice; Peptides, Cyclic; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Platelet Glycoprotein GPIIb-IIIa Complex; Tirofiban; Treatment Outcome; Tyrosine | 1999 |
Inhibitory effect of sulfur-containing compounds in Scorodocarpus borneensis Becc. on the aggregation of rabbit platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Arachidonic Acid; Aspirin; Blood Coagulation Factors; Collagen; Hemostatics; Hexanes; Inhibitory Concentration 50; Octanes; Plant Extracts; Plants, Edible; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Sulfur Compounds; Thrombin; Trees; Vasoconstrictor Agents | 1999 |
Anandamide activates human platelets through a pathway independent of the arachidonate cascade.
Topics: Adenosine Diphosphate; Amides; Amidohydrolases; Amino Acid Sequence; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcium; Cannabinoids; Endocannabinoids; Ethanolamines; Humans; In Vitro Techniques; Molecular Sequence Data; Palmitic Acids; Platelet Activation; Polyunsaturated Alkamides | 1999 |
Clinico-haematological profile of isolated PF3 availability defect: therapeutic potential of soya bean--a pilot study.
Topics: Adenosine Diphosphate; Adolescent; Adrenergic Agonists; Adult; Aged; Arachidonic Acid; Biomarkers; Blood Platelet Disorders; Child; Child, Preschool; Collagen; Epinephrine; Female; Glycine max; Humans; Male; Middle Aged; Phytotherapy; Pilot Projects; Platelet Aggregation; Platelet Factor 3; Ristocetin | 1999 |
Effect of the crude extract of Cestrum parqui on carrageenin-induced rat paw oedema and aggregation of human blood platelets.
Topics: Adenosine Diphosphate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Carrageenan; Edema; Male; Pakistan; Plant Extracts; Platelet Activating Factor; Platelet Aggregation; Rats; Rats, Sprague-Dawley; Solanaceae | 1999 |
Effect of protopine on cytosolic Ca2+ in rabbit platelets.
Topics: Adenosine Diphosphate; Alkaloids; Animals; Arachidonic Acid; Benzophenanthridines; Berberine Alkaloids; Biological Transport, Active; Blood Platelets; Calcium; Female; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rabbits | 1999 |
Inhibitory effects of H2-receptor antagonists on platelet function in vitro.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Aspirin; Blood Platelets; Cimetidine; Collagen; Famotidine; Female; Heterocyclic Compounds, 1-Ring; Histamine H2 Antagonists; Humans; In Vitro Techniques; Male; Middle Aged; P-Selectin; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Ranitidine; Structure-Activity Relationship | 1999 |
p-Aminobenzoic acid and its metabolite p-acetamidobenzoic acid inhibit agonist-induced aggregation and arachidonic acid-induced [Ca2+]i transients in human platelets.
Topics: 4-Aminobenzoic Acid; Adenosine Diphosphate; Arachidonic Acid; Blood Platelets; Calcium; Humans; para-Aminobenzoates; Platelet Aggregation; Platelet Aggregation Inhibitors | 1999 |
Effects of catechins on human blood platelet aggregation and lipid peroxidation.
Topics: Adenosine Diphosphate; Arachidonic Acid; Blood Platelets; Catechin; Epinephrine; Humans; Lipid Peroxidation; Platelet Aggregation Inhibitors | 1999 |
Enhanced inhibition of platelet aggregation in-vitro by niosome-encapsulated indomethacin.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Capsules; Delayed-Action Preparations; Dose-Response Relationship, Drug; Epinephrine; Humans; In Vitro Techniques; Indomethacin; Platelet Aggregation Inhibitors; Polysorbates; Ristocetin; Surface-Active Agents | 1999 |
Comparison of in vitro and ex vivo antiplatelet effects of 1,2-benzisothiazolin-3-one and its 2-amino derivative.
Topics: Adenosine Diphosphate; Adolescent; Adult; Animals; Arachidonic Acid; Collagen; Female; Humans; In Vitro Techniques; Indicators and Reagents; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Thiazoles | 1999 |
Optimal conditions for simultaneous measurement of platelet aggregation and ATP secretion in canine whole blood.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Blood Platelets; Blood Specimen Collection; Collagen; Dogs; Female; Male; Platelet Aggregation; Platelet Count; Reproducibility of Results; Thrombin | 2000 |
Early detection of preeclampsia by determination of platelet aggregability.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Case-Control Studies; Collagen; Female; Humans; In Vitro Techniques; Platelet Aggregation; Pre-Eclampsia; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, Second; Pregnancy Trimester, Third | 2000 |
Characteristics of collagen-induced Ca2+ mobilization in bovine platelets.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Aspirin; Blood Platelets; Calcium; Cattle; Collagen; Egtazic Acid; Enzyme Inhibitors; Estrenes; Fluorescent Dyes; Fura-2; Humans; Manganese; Phosphoadenosine Phosphosulfate; Platelet Aggregation Inhibitors; Pyrrolidinones; Thapsigargin; Thrombin; Type C Phospholipases | 2000 |
Superoxide anion and hydroxyl radical release by collagen-induced platelet aggregation--role of arachidonic acid metabolism.
Topics: Adenosine Diphosphate; Arachidonic Acid; Ascorbic Acid; Blood Platelets; Collagen; Humans; Hydroxyl Radical; In Vitro Techniques; Platelet Aggregation; Salicylic Acid; Superoxides | 2000 |
Purification, cloning, expression, and mechanism of action of a novel platelet aggregation inhibitor from the salivary gland of the blood-sucking bug, Rhodnius prolixus.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Animals; Arachidonic Acid; Blood Platelets; Calcium; Cattle; Cell Adhesion; Cell Aggregation; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Cloning, Molecular; Collagen; Crotalid Venoms; Cyclic AMP; DNA, Complementary; Dose-Response Relationship, Drug; Humans; Insect Proteins; Lectins, C-Type; Molecular Sequence Data; Platelet Aggregation Inhibitors; Rabbits; Rhodnius; Salivary Glands; Salivary Proteins and Peptides; Sequence Homology, Amino Acid; Thromboxane A2; Time Factors; Tryptophan | 2000 |
Effects of acute, moderate ethanol consumption on human platelet aggregation in platelet-rich plasma and whole blood.
Topics: Adenosine Diphosphate; Adult; Alcohol Drinking; Arachidonic Acid; Central Nervous System Depressants; Collagen; Ethanol; Female; Humans; Male; Middle Aged; Platelet Aggregation | 2000 |
PLA(2) dependence of diaphragm mitochondrial formation of reactive oxygen species.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Calcium; Cyanides; Diaphragm; Electron Transport Complex I; Electron Transport Complex IV; Enzyme Inhibitors; Hydrogen Peroxide; Malates; Male; Melitten; Mitochondria; NADH, NADPH Oxidoreductases; NADPH Oxidases; Onium Compounds; Phosphodiesterase Inhibitors; Phospholipases A; Pyruvic Acid; Rats; Rats, Inbred Strains; Reactive Oxygen Species; Rotenone; Sepsis; Terpenes; Uncoupling Agents | 2000 |
Effect of aspirin on platelet desaggregation induced by SR121566, a potent GP-IIb/IIIa antagonist.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Aspirin; Benzylamines; Blood Flow Velocity; Blood Platelets; Carotid Arteries; Disease Models, Animal; Electric Stimulation; Female; Fibrinolytic Agents; Humans; Male; Oligopeptides; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Rabbits; Recombinant Proteins; Thiazoles; Thrombosis; Thrombospondins; Tissue Plasminogen Activator | 2000 |
Effects of mycophenolate mofetil and mycophenolic acid on platelet aggregation in vitro.
Topics: Adenosine Diphosphate; Arachidonic Acid; Collagen; Humans; Immunosuppressive Agents; In Vitro Techniques; Kidney Failure, Chronic; Mycophenolic Acid; Platelet Aggregation; Ristocetin; Uremia | 2000 |
2-Amino-Benzo[d]isothiazol-3-one derivatives: synthesis and assessment of their antiplatelet/spasmolytic effects.
Topics: Adenosine Diphosphate; Animals; Aorta; Arachidonic Acid; Benzaldehydes; Guinea Pigs; Ileum; Inhibitory Concentration 50; Male; Models, Animal; Muscle Contraction; Parasympatholytics; Platelet Aggregation; Platelet Aggregation Inhibitors; Thiazoles | 2000 |
Defective platelet response to arachidonic acid and thromboxane A(2) in subjects with Pl(A2) polymorphism of beta(3) subunit (glycoprotein IIIa).
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adult; Arachidonic Acid; Aspirin; beta-Thromboglobulin; Blood Platelets; Coronary Disease; Female; Flow Cytometry; Genotype; Humans; Male; Middle Aged; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Polymorphism, Genetic; Risk Factors; Statistics, Nonparametric; Thrombin; Thromboxane A2 | 2000 |
Abciximab treatment in vitro after aspirin treatment in vivo has additive effects on platelet aggregation, ATP release, and P-selectin expression.
Topics: Abciximab; Adenosine Diphosphate; Adenosine Triphosphate; Adult; Antibodies, Monoclonal; Arachidonic Acid; Aspirin; Blood Platelets; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Female; Humans; Immunoglobulin Fab Fragments; Male; Middle Aged; P-Selectin; Platelet Aggregation; Platelet Aggregation Inhibitors | 2000 |
Pathogenetic analysis of three cases with a bleeding disorder characterized by defective platelet aggregation induced by Ca2+ ionophores.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adult; Arachidonic Acid; Blood Platelet Disorders; Blood Proteins; Calcimycin; Calcium; Collagen; Female; Humans; Ionophores; Male; Middle Aged; Myosin Light Chains; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Membrane Glycoproteins; Ristocetin; Thrombin; Thromboxane A2 | 2001 |
Binding of recombinant apolipoprotein(a) to human platelets and effect on platelet aggregation.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Aminocaproic Acid; Apolipoproteins; Apoprotein(a); Arachidonic Acid; Binding, Competitive; Collagen; Fibrinogen; Humans; Lipoprotein(a); Molecular Sequence Data; Plasminogen; Platelet Aggregation; Protein Binding; Protein Isoforms; Proteins; Receptors, Thrombin; Recombinant Proteins; Thrombin; Tissue Plasminogen Activator | 2001 |
Effect of gamma-hydroxybutyric acid on human platelet aggregation in vitro.
Topics: Adenosine Diphosphate; Adult; Alcohol-Related Disorders; Arachidonic Acid; Collagen; Dose-Response Relationship, Drug; Drug Antagonism; Female; Humans; Male; Molecular Conformation; Platelet Aggregation; Receptors, N-Methyl-D-Aspartate; Sodium Oxybate; Thrombin; Thromboxane B2 | 2001 |
Synthesis and pharmacological evaluation of 2,5-cycloamino-5H-[1]benzopyrano[4,3-d]pyrimidines endowed with in vitro antiplatelet activity.
Topics: Adenosine Diphosphate; Analgesics; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Benzopyrans; Collagen; Disease Models, Animal; Edema; Guinea Pigs; Pain; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrimidines; Rats | 2001 |
Beta-lactam antibiotic-mediated changes in platelet reactivity and vascular endothelial functions.
Topics: Adenosine Diphosphate; Animals; Anti-Bacterial Agents; Aorta, Thoracic; Apyrase; Arachidonic Acid; Aztreonam; Blood Platelets; Cattle; Ceftazidime; Ceftriaxone; Collagen; Endothelium, Vascular; Epoprostenol; Humans; In Vitro Techniques; Platelet Activation; Platelet Aggregation Inhibitors; Radioimmunoassay; Time Factors; Tissue Plasminogen Activator | 2001 |
Synthesis and antiplatelet activity of some 2,7-di(N-cycloamino)-3-phenyl-1,8-naphthyridine derivatives.
Topics: Adenosine Diphosphate; Arachidonic Acid; Blood Platelets; Chemical Phenomena; Chemistry, Physical; Collagen; Cyclic AMP; Humans; In Vitro Techniques; Indicators and Reagents; Magnetic Resonance Spectroscopy; Naphthyridines; Platelet Aggregation; Platelet Aggregation Inhibitors; Spectrophotometry, Infrared; Structure-Activity Relationship | 2001 |
Platelet storage pool deficiency of alpha and delta granules.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Bleeding Time; Blood Platelets; Cholelithiasis; Collagen; Cytoplasmic Granules; Epinephrine; Erythrocyte Transfusion; Female; Humans; Microscopy, Electron; Platelet Aggregation; Platelet Storage Pool Deficiency; Platelet Transfusion | 2001 |
Effects of adenosine on thrombosis and thrombolysis in a canine experimental preparation.
Topics: Adenosine; Adenosine Diphosphate; Animals; Arachidonic Acid; Blood Flow Velocity; Carotid Arteries; Carotid Artery Thrombosis; Coronary Circulation; Coronary Thrombosis; Disease Models, Animal; Dogs; Electric Injuries; Female; Fibrinolytic Agents; Male; Platelet Aggregation; Thrombolytic Therapy; Time Factors; Tissue Plasminogen Activator | 2001 |
Modulation of in vitro platelet 5-HT release by species of Erythrina and Cymbopogon.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Blood Platelets; Collagen; Dose-Response Relationship, Drug; Epinephrine; Erythrina; Humans; Kinetics; Methanol; Methylene Chloride; Migraine Disorders; Plant Extracts; Plants, Medicinal; Platelet Aggregation; Serotonin | 2001 |
The roles of LAT in platelet signaling induced by collagen, TxA2, or ADP.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adaptor Proteins, Signal Transducing; Adenosine Diphosphate; Animals; Antibodies; Arachidonic Acid; Blood Platelets; Carrier Proteins; Collagen; Dose-Response Relationship, Drug; Membrane Proteins; Mice; Mice, Knockout; Phosphoproteins; Platelet Aggregation; Signal Transduction; Thromboxane A2; Vasoconstrictor Agents | 2002 |
Effect of diazepam and clonazepam on the function of isolated rat platelet and neutrophil.
Topics: Adenosine Diphosphate; Alprostadil; Animals; Arachidonic Acid; Blood Platelets; Calcium Signaling; Clonazepam; Diazepam; Drug Interactions; Isoquinolines; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activation; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Reactive Oxygen Species; Receptors, GABA-A; Respiratory Burst; Thrombin | 2002 |
Isolation and structural elucidation of biologically active phospholipids from Scytonema julianum (cyanobacteria).
Topics: Adenosine Diphosphate; Arachidonic Acid; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cyanobacteria; Lipid Metabolism; Lipids; Mass Spectrometry; Models, Chemical; Phosphatidylcholines; Phospholipids; Spectrometry, Mass, Electrospray Ionization; Time Factors | 2002 |
Evaluation of antilipid peroxidative action of propolis ethanol extract.
Topics: Adenosine Diphosphate; alpha-Linolenic Acid; Animals; Arachidonic Acid; Ascorbic Acid; Ethanol; Free Radical Scavengers; Kinetics; Linoleic Acid; Lipid Peroxidation; Male; Microsomes, Liver; Propolis; Rats; Rats, Wistar | 2002 |
Antiplatelet aggregation activity of diterpene alkaloids from Spiraea japonica.
Topics: Adenosine Diphosphate; Alkaloids; Animals; Arachidonic Acid; Aspirin; Blood Platelets; Diterpenes; Female; Fibrinolytic Agents; Ginkgolides; In Vitro Techniques; Indicators and Reagents; Lactones; Male; Plant Extracts; Plant Roots; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rabbits; Spiraea | 2002 |
Involvement of GD3 in platelet activation. A novel association with Fcgamma receptor.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Blotting, Western; Cells, Cultured; Collagen; Cytoskeleton; Enzyme Inhibitors; Gangliosides; Humans; Phospholipases A; Platelet Activation; Receptors, IgG; src-Family Kinases | 2002 |
Progress in 5H[1]benzopyrano[4,3-d]pyrimidin-5-amine series: 2-methoxy derivatives effective as antiplatelet agents with analgesic activity.
Topics: Adenosine Diphosphate; Analgesics, Non-Narcotic; Animals; Arachidonic Acid; Collagen; Gastric Mucosa; Guinea Pigs; Mice; Pain Measurement; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrimidines; Rats; Structure-Activity Relationship | 2002 |
[The effects of starfish sterol on platelet aggregation].
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Male; Materia Medica; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Rats; Rats, Sprague-Dawley; Starfish; Sterols; Thrombosis | 2000 |
The effect of propofol on the interaction of platelets with leukocytes and erythrocytes in surgical patients.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Adult; Anesthetics, Intravenous; Arachidonic Acid; Blood Platelets; Blood Pressure; Collagen; Erythrocytes; Female; Heart Rate; Humans; Leukocytes; Male; Middle Aged; Nitrates; Platelet Aggregation; Propofol; Surgical Procedures, Operative | 2003 |
Evidence for a role for Galphai1 in mediating weak agonist-induced platelet aggregation in human platelets: reduced Galphai1 expression and defective Gi signaling in the platelets of a patient with a chronic bleeding disorder.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Blood Platelet Disorders; Blood Platelets; Calcium; Carbon Radioisotopes; Cell Membrane; Colforsin; Collagen; Cyclic AMP; Diglycerides; DNA, Complementary; Epinephrine; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Male; Monocytes; Phosphorus Radioisotopes; Platelet Aggregation; Sequence Analysis, DNA; Serotonin; Signal Transduction; Thrombin; Thromboxane B2; Tritium | 2003 |
Obesity is associated with impaired platelet-inhibitory effect of acetylsalicylic acid in nondiabetic subjects.
Topics: Adenosine Diphosphate; Analysis of Variance; Arachidonic Acid; Arteriosclerosis; Aspirin; Blood Glucose; Body Mass Index; Body Weight; Dose-Response Relationship, Drug; Female; Humans; Insulin Resistance; Male; Middle Aged; Obesity; Platelet Aggregation; Platelet Aggregation Inhibitors; Risk Factors | 2003 |
Effects of plumbagin on platelet aggregation and platelet-neutrophil interactions.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Blood Platelets; In Vitro Techniques; Male; Naphthoquinones; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Rabbits | 2003 |
TRA-418, a novel compound having both thromboxane A(2) receptor antagonistic and prostaglandin I(2) receptor agonistic activities: its antiplatelet effects in human and animal platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Arachidonic Acid; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Cats; Cell Membrane; Cyclic AMP; Dogs; Epoprostenol; Fatty Acids, Unsaturated; Haplorhini; Heart Rate; Humans; Hydrazines; Inhibitory Concentration 50; Kinetics; Models, Chemical; Oxazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Binding; Rats; Receptors, Thromboxane; Receptors, Thromboxane A2, Prostaglandin H2; Vasoconstrictor Agents | 2003 |
Mechanisms of the priming effect of low doses of lipopoly-saccharides on leukocyte-dependent platelet aggregation in whole blood.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Blood; Blood Platelets; Cell Adhesion; Drug Interactions; Epinephrine; Humans; Leukocytes; Lipopolysaccharide Receptors; Lipopolysaccharides; Membrane Glycoproteins; Platelet Activating Factor; Platelet Aggregation; Receptors, Cell Surface; Toll-Like Receptor 4; Toll-Like Receptors | 2003 |
Platelet function tests using platelet aggregometry: need for repetition of the test for diagnosis of defective platelet function.
Topics: Adenosine Diphosphate; Arachidonic Acid; Bernard-Soulier Syndrome; Blood Coagulation Disorders; Blood Platelets; Collagen; Flow Cytometry; Humans; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Reference Values; Ristocetin; Thrombasthenia; von Willebrand Diseases | 2003 |
H2O2-induced platelet aggregation and increase in intracellular Ca2+ concentration are blocked by inhibitors of intracellular signaling.
Topics: Adenosine Diphosphate; Arachidonic Acid; Blood Platelets; Calcium; Calcium Signaling; Cyclic AMP; Cyclic GMP; Humans; Hydrogen Peroxide; Platelet Aggregation; Platelet Aggregation Inhibitors | 2003 |
The influence of VIP and epoprostenol on platelet CD62P expression and primary haemostasis in vitro.
Topics: Adenosine Diphosphate; Analysis of Variance; Arachidonic Acid; Blood Platelets; Epoprostenol; Flow Cytometry; Hemostasis; Humans; P-Selectin; Platelet Activation; Platelet Function Tests; Vasoactive Intestinal Peptide | 2004 |
Evaluation of effects of rofecoxib on platelet function in an in vitro model of thrombosis with circulating human blood.
Topics: Adenosine Diphosphate; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Blood Platelets; Cell Adhesion; Collagen; Cyclooxygenase Inhibitors; Endothelium; Humans; Lactones; Platelet Aggregation; Sulfones; Thrombosis | 2004 |
Evaluation of anti-platelet aggregatory effects of aspirin, cilostazol and ramatroban on platelet-rich plasma and whole blood.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine Diphosphate; Arachidonic Acid; Aspirin; Carbazoles; Cilostazol; Collagen; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclooxygenase Inhibitors; Humans; Microscopy, Confocal; Phosphodiesterase Inhibitors; Plasma; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptors, Thromboxane A2, Prostaglandin H2; Reproducibility of Results; Sulfonamides; Tetrazoles | 2004 |
A novel modification of the Thrombelastograph assay, isolating platelet function, correlates with optical platelet aggregation.
Topics: Adenosine Diphosphate; Arachidonic Acid; Batroxobin; Blood Coagulation; Blood Platelets; Dose-Response Relationship, Drug; Factor XIIIa; Hemostatics; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Point-of-Care Systems; Thrombelastography | 2004 |
Platelet 12-lipoxygenase activation via glycoprotein VI: involvement of multiple signaling pathways in agonist control of H(P)ETE synthesis.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Amino Acid Motifs; Arachidonate 12-Lipoxygenase; Arachidonic Acid; Blood Platelets; Calcimycin; Calcium Signaling; Carrier Proteins; Collagen; Cyclooxygenase 1; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Humans; Inflammation; Isoenzymes; Leukotrienes; Membrane Proteins; p38 Mitogen-Activated Protein Kinases; Peptides; Phosphorylation; Platelet Activation; Platelet Endothelial Cell Adhesion Molecule-1; Platelet Membrane Glycoproteins; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Protein Processing, Post-Translational; Protein Transport; Quinolines; Receptors, IgG; Thrombin | 2004 |
Platelet hyperreactivity in hemodialysis patients with frequently occluded vascular access.
Topics: Adenosine Diphosphate; Arachidonic Acid; Calcium; Catheters, Indwelling; Diabetes Mellitus; Female; Graft Occlusion, Vascular; Humans; Male; Middle Aged; Platelet Activating Factor; Platelet Activation; Renal Dialysis; Thrombin; Thrombosis | 2004 |
Defect in regulation of Ca2+ movement in platelets from patients with systemic lupus erythematosus.
Topics: Adenosine Diphosphate; Arachidonic Acid; Blood Platelets; Calcium; Calcium Signaling; Female; Fluorescent Dyes; Fura-2; Humans; Lupus Erythematosus, Systemic; Patients; Platelet Activating Factor; Thrombin | 2005 |
Antiplatelet activity of BRX-018, (6aS,cis)-malonic acid 3-acetoxy-6a9-bis-(2-methoxycarbonyl-acetoxy)-6,6a,7,11b-tetrahydro-indeno[2,1-c]chromen-10-yl ester methylester.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Benzopyrans; Blood Platelets; Calcimycin; Calcium; Cattle; Cell Degranulation; Collagen; In Vitro Techniques; Ionophores; Male; Malonates; Phospholipases A; Phospholipases A2; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Swine; Thrombin; Thromboxane B2 | 2005 |
Pulmonary and systemic hemodynamic responses to intravenous prostacyclin in broilers.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Blood Flow Velocity; Blood Pressure; Chickens; Epoprostenol; Hemodynamics; Infusions, Intravenous; Lung; Male; Pulmonary Artery; Vasodilation | 2005 |
Correlation between in vitro aggregation and thromboxane A2 production in fresh, liquid-preserved, and cryopreserved human platelets: effect of agonists, pH, and plasma and saline resuspension.
Topics: Adenosine Diphosphate; Arachidonic Acid; Blood Platelets; Blood Preservation; Cryopreservation; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Plasma; Platelet Aggregation; Platelet Transfusion; Sodium Chloride; Thromboxane A2 | 2005 |
Platelet aggregation testing in platelet-rich plasma: description of procedures with the aim to develop standards in the field.
Topics: Adenosine Diphosphate; Arachidonic Acid; Blood Platelet Disorders; Blood Platelets; Clinical Laboratory Techniques; Collagen; Dose-Response Relationship, Drug; Epinephrine; Humans; Plasma; Platelet Aggregation; Reference Values; Ristocetin; Thrombin | 2005 |
Platelet function disorder in Gardner-Diamond syndrome: a case report and review of the literature.
Topics: Adenosine Diphosphate; Adolescent; Arachidonic Acid; Blood Coagulation Disorders; Blood Platelet Disorders; Contusions; Female; Gardner Syndrome; Humans; Mental Disorders; Platelet Aggregation; Psychotic Disorders; Syndrome | 2005 |
Assessment of the antiplatelet effects of low to medium dose aspirin in the early and late phases after ischaemic stroke and TIA.
Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Blood Platelets; Case-Control Studies; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Resistance; Epinephrine; Female; Humans; Ischemic Attack, Transient; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prostaglandin-Endoperoxide Synthases; Stroke; von Willebrand Factor | 2005 |
A new point-of-care method for monitoring anti-platelet therapy: application of the cone and plate(let) analyzer.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Aspirin; Blood Proteins; Drug Monitoring; Humans; Membrane Proteins; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Platelet Function Tests; Point-of-Care Systems; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Sensitivity and Specificity | 2005 |
Variables influencing Platelet Function Analyzer-100 closure times in healthy individuals.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Bleeding Time; Blood Donors; Blood Specimen Collection; Collagen; Female; Hemostasis; Humans; Linear Models; Male; Mass Screening; Middle Aged; Platelet Aggregation; Platelet Function Tests; Reproducibility of Results; Sensitivity and Specificity; Sex Factors; Statistics, Nonparametric | 2005 |
Agonists-induced platelet activation varies considerably in healthy male individuals: studies by flow cytometry.
Topics: Adenosine Diphosphate; Adult; Aged; Arachidonic Acid; Blood Platelets; Collagen; Epinephrine; Flow Cytometry; Humans; Male; Middle Aged; P-Selectin; Peptide Fragments; Platelet Activation; Ristocetin | 2006 |
Platelet emboli and ischemia in rabbit's brain caused by ADP or arachidonic acid and the protective effect of ASA and dipyridamole.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Aspirin; Dipyridamole; Intracranial Embolism; Ischemic Attack, Transient; Male; Pia Mater; Platelet Aggregation; Rabbits | 1977 |
Anti-platelet effects of bioactive compounds isolated from the bark of Rhus verniciflua Stokes.
Topics: Adenosine Diphosphate; Adult; Animals; Arachidonic Acid; Blood Platelets; Calcium; Collagen; Female; Flow Cytometry; Humans; Hydrolyzable Tannins; Male; Mice; Mice, Inbred ICR; P-Selectin; Plant Bark; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Membrane Glycoproteins; Pulmonary Embolism; Rhus | 2006 |
Platelet ADP response deteriorates in synthetic storage media.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Arachidonic Acid; Blood Platelets; Blood Preservation; Collagen; Cryopreservation; Humans; Organ Preservation Solutions; P-Selectin; Peptide Fragments; Plasma; Platelet Adhesiveness; Platelet Aggregation; Stress, Mechanical; Vasoconstrictor Agents | 2006 |
Residual arachidonic acid-induced platelet activation via an adenosine diphosphate-dependent but cyclooxygenase-1- and cyclooxygenase-2-independent pathway: a 700-patient study of aspirin resistance.
Topics: Adenosine Diphosphate; Arachidonic Acid; Aspirin; Clopidogrel; Coronary Artery Disease; Cyclooxygenase 1; Cyclooxygenase 2; Dose-Response Relationship, Drug; Drug Resistance; Female; Flow Cytometry; Humans; Male; Middle Aged; Multivariate Analysis; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Recurrence; Signal Transduction; Thrombosis; Thromboxane B2; Ticlopidine; Time Factors; Treatment Refusal | 2006 |
Relation between atherosclerosis risk factors and aspirin resistance in a primary prevention population.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Aspirin; Coronary Artery Disease; Drug Resistance; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Risk Factors; Thromboxane B2; Whole Blood Coagulation Time | 2006 |
Activation and impairment of platelet function in vitro by fatty acid ethyl ester, a nonoxidative ethanol metabolite: effect of fatty acid ethyl esters on human platelets.
Topics: Adenosine Diphosphate; Arachidonic Acid; beta-Thromboglobulin; Blood Platelets; Central Nervous System Depressants; Cyclic AMP; Dose-Response Relationship, Drug; Epinephrine; Esters; Ethanol; Fatty Acids; Humans; In Vitro Techniques; Oleic Acids; Platelet Activation; Platelet Aggregation; Platelet Function Tests; Thromboxane A2; Time Factors | 2006 |
Antiplatelet and antithrombotic activities of Korean Red Ginseng.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Administration, Oral; Animals; Arachidonic Acid; Blood Coagulation Tests; Carboxymethylcellulose Sodium; Carotid Artery Injuries; Carotid Artery Thrombosis; Collagen; Dose-Response Relationship, Drug; Fibrinolytic Agents; Ginsenosides; Korea; Male; Panax; Partial Thromboplastin Time; Platelet Aggregation; Platelet Aggregation Inhibitors; Prothrombin Time; Rabbits; Rats; Rats, Sprague-Dawley | 2006 |
Letter by Kronish et al regarding article, "Residual arachidonic acid-induced platelet activation via an adenosine diphosphate-dependent but cyclooxygenase-1- and cyclooxygenase-2-independent pathway: a 700-patient study of aspirin resistance".
Topics: Adenosine Diphosphate; Arachidonic Acid; Aspirin; Coronary Disease; Cyclooxygenase 1; Cyclooxygenase 2; Drug Resistance; Humans; Patient Compliance; Platelet Activation; Reproducibility of Results | 2007 |
[Interindividual variability in the laboratory response to the aspirin-clopidogrel combination: are patients with stent occlusion "resistant" to treatment?].
Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Arachidonic Acid; Aspirin; Clopidogrel; Collagen; Coronary Restenosis; Drug Resistance; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Predictive Value of Tests; Ticlopidine | 2007 |
Hyperresponsiveness of platelets in ischemic stroke.
Topics: Adenosine Diphosphate; Adult; Aged; Arachidonic Acid; Biomarkers; Blood Platelets; Brain Ischemia; Collagen; Epinephrine; Female; Follow-Up Studies; Humans; Ischemic Attack, Transient; Logistic Models; Male; Middle Aged; Platelet Activation; Platelet Aggregation; Platelet Function Tests; Predictive Value of Tests; Recurrence; Risk Assessment; Risk Factors; ROC Curve; Severity of Illness Index; Stroke; Time Factors | 2007 |
Residual platelet reactivity is associated with clinical and laboratory characteristics in patients with ischemic heart disease undergoing PCI on dual antiplatelet therapy.
Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Arachidonic Acid; Aspirin; Blood Platelets; Clopidogrel; Female; Humans; Male; Myocardial Ischemia; Platelet Aggregation Inhibitors; Protein Isoforms; Risk Factors; Ticlopidine | 2007 |
Reproducibility of platelet function testing.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adult; Arachidonic Acid; Collagen; Epinephrine; Female; Genetic Variation; Humans; Luminescent Measurements; Male; Middle Aged; Nephelometry and Turbidimetry; Platelet Aggregation; Platelet Function Tests; Reproducibility of Results; Ristocetin; Thrombin | 2007 |
[Modified platelet aggregation test in patients on ASA and/or clopidogrel].
Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Clopidogrel; Collagen; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epinephrine; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Reference Values; Thrombosis; Ticlopidine | 2007 |
In vitro antiplatelet activity of flavonoids from Leuzea carthamoides.
Topics: Adenosine Diphosphate; Arachidonic Acid; Blood Platelets; Chromones; Collagen; Dose-Response Relationship, Drug; Flavanones; Flavonoids; Humans; In Vitro Techniques; Kaempferols; Leuzea; Male; Plant Leaves; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Thrombin | 2008 |
Standardization of light transmittance aggregometry for monitoring antiplatelet therapy: an adjustment for platelet count is not necessary.
Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Algorithms; Arachidonic Acid; Aspirin; Calibration; Clopidogrel; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Nephelometry and Turbidimetry; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Platelet Function Tests; Platelet-Rich Plasma; Sensitivity and Specificity; Thrombophilia; Ticlopidine | 2008 |
Comment on "hyperresponsiveness of platelets in ischemic stroke" by Fateh-Moghadam et al.
Topics: Adenosine Diphosphate; Arachidonic Acid; Aspirin; Biomarkers; Blood Platelets; Brain Ischemia; Epinephrine; Humans; Ischemic Attack, Transient; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Recurrence; Stroke; Time Factors | 2008 |
[Study on composing mechanism by effect of disassembled compositions of Yiqi Huoxue decoction on platelet aggregation of health adults].
Topics: Adenosine Diphosphate; Adult; Angelica sinensis; Arachidonic Acid; Astragalus propinquus; Drug Combinations; Drug Synergism; Drugs, Chinese Herbal; Female; Humans; Male; Middle Aged; Plants, Medicinal; Platelet Activating Factor; Platelet Aggregation; Young Adult | 2007 |
Aspirin non-responsiveness in Korean subjects on dual anti-platelet treatment determined by two different platelet function assays.
Topics: Adenosine Diphosphate; Adult; Aged; Arachidonic Acid; Asian People; Aspirin; Bleeding Time; Case-Control Studies; Clopidogrel; Collagen; Drug Resistance; Epinephrine; Female; Humans; Korea; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine | 2008 |
An evaluation of methods for determining reference intervals for light transmission platelet aggregation tests on samples with normal or reduced platelet counts.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Arachidonic Acid; Blood Platelets; Cell Size; Collagen; Data Interpretation, Statistical; Epinephrine; Feasibility Studies; Humans; Light; Platelet Aggregation; Platelet Count; Platelet Function Tests; Prospective Studies; Reference Values; Ristocetin; Statistics, Nonparametric; Thrombocytopenia | 2008 |
Anti-platelet effects of flavonoids and flavonoid-glycosides from Sophora japonica.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Arachidonic Acid; Collagen; Flavonoids; Fruit; Glycosides; In Vitro Techniques; Magnetic Resonance Spectroscopy; Plant Leaves; Plant Stems; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Sophora; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Thromboxane A2 | 2008 |
(3S)-N-(L-Aminoacyl)-1,2,3,4-tetrahydroisoquinolines, a class of novel antithrombotic agents: synthesis, bioassay, 3D QSAR, and ADME analysis.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Biological Assay; Dose-Response Relationship, Drug; Fibrinolytic Agents; Molecular Structure; Platelet Activating Factor; Platelet Aggregation; Quantitative Structure-Activity Relationship; Rats; Tetrahydroisoquinolines; Thrombin | 2008 |
Testing agonist-induced platelet aggregation by the Impact-R [Cone and plate(let) analyzer (CPA)].
Topics: Adenosine Diphosphate; Adult; Alprostadil; Arachidonic Acid; Blood Coagulation Disorders; Collagen; Epinephrine; Female; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation; Platelet Function Tests; Ristocetin; Young Adult | 2008 |
Acidic peptides enhanced genistein-dependent inhibition of human platelet aggregation: potential protective effect of digestible peptides plus genistein against atherosclerosis.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Atherosclerosis; Collagen; Dipeptides; Epinephrine; Female; Genistein; Humans; Male; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Soybean Proteins | 2008 |
Effect of Iron Therapy on Platelet Function among Iron-Deficient Women with Unexplained Menorrhagia.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Anemia, Iron-Deficiency; Arachidonic Acid; Collagen; Female; Humans; Iron; Menorrhagia; Platelet Aggregation; Platelet Function Tests; Ristocetin | 2008 |
Predicting thrombotic events: creating a complex approach for a complex condition.
Topics: Adenosine Diphosphate; Angioplasty, Balloon, Coronary; Arachidonic Acid; Aspirin; Clopidogrel; Collagen; Drug Resistance; Drug Therapy, Combination; Drug-Eluting Stents; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Point-of-Care Systems; Predictive Value of Tests; Reproducibility of Results; Risk Assessment; Risk Factors; ROC Curve; Thrombosis; Ticlopidine | 2008 |
The effect of ex vivo anticoagulants on whole blood platelet aggregation.
Topics: Adenosine Diphosphate; Anticoagulants; Arachidonic Acid; Arginine; Azetidines; Benzylamines; Blood Platelets; Citric Acid; Collagen; Female; Heparin; Hirudins; Humans; Male; Peptide Fragments; Pipecolic Acids; Platelet Aggregation; Platelet Function Tests; Recombinant Proteins; Ristocetin; Sulfonamides; Time Factors | 2009 |
Antiplatelet activity of Allium ursinum and Allium sativum.
Topics: Adenosine Diphosphate; Adult; Allium; Arachidonic Acid; Calcimycin; Collagen; Dose-Response Relationship, Drug; Epinephrine; Female; Garlic; Humans; In Vitro Techniques; Male; Plant Extracts; Platelet Aggregation; Platelet Aggregation Inhibitors | 2009 |
Evaluation of the platelet count drop method for assessment of platelet function in comparison with "gold standard" light transmission aggregometry.
Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Platelet Function Tests; Reproducibility of Results; Ticlopidine | 2009 |
Antiplatelet effects of piplartine, an alkamide isolated from Piper tuberculatum: possible involvement of cyclooxygenase blockade and antioxidant activity.
Topics: Adenosine Diphosphate; Antioxidants; Arachidonic Acid; Collagen; Cyclooxygenase Inhibitors; Drug Interactions; Humans; In Vitro Techniques; Piperaceae; Piperidones; Plant Roots; Platelet Aggregation; Platelet-Rich Plasma; Thrombin | 2009 |
The effect of milrinone on platelet activation as determined by TEG platelet mapping.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Blood Platelets; Cyclic AMP; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Milrinone; Phosphodiesterase Inhibitors; Platelet Activation; Platelet Aggregation Inhibitors; Thrombelastography | 2009 |
The impact of intravenous aspirin administration on platelet aspirin resistance after on-pump coronary artery bypass surgery.
Topics: Adenosine Diphosphate; Administration, Oral; Adult; Aged; Aged, 80 and over; Arachidonic Acid; Aspirin; Collagen; Coronary Artery Bypass; Drug Resistance; Female; Humans; Injections, Intravenous; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests | 2009 |
Differences in responses of platelets to fluid shear stress in patients with peripheral artery disease (PAD) and coronary artery disease (CAD).
Topics: Adenosine Diphosphate; Arachidonic Acid; Collagen; Coronary Artery Disease; Epinephrine; Humans; In Vitro Techniques; Male; Middle Aged; P-Selectin; Peripheral Vascular Diseases; Platelet Activation; Platelet Aggregation; Stress, Mechanical | 2009 |
Variability in aggregometry response before and after initiation of clopidogrel therapy.
Topics: Adenosine Diphosphate; Arachidonic Acid; Aspirin; Case-Control Studies; Clopidogrel; Demography; Female; Humans; Male; Middle Aged; Peptide Fragments; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Reproducibility of Results; Ticlopidine | 2009 |
Spice active principles as the inhibitors of human platelet aggregation and thromboxane biosynthesis.
Topics: Acrolein; Adenosine Diphosphate; Alkaloids; Allyl Compounds; Arachidonic Acid; Benzodioxoles; Calcimycin; Capsaicin; Collagen Type III; Curcumin; Eugenol; Humans; Malondialdehyde; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Polyunsaturated Alkamides; Quercetin; Spices; Sulfides; Thromboxanes | 2009 |
The formation of monocyte-platelet aggregates is independent of on-treatment residual agonists'-inducible platelet reactivity.
Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Angioplasty, Balloon; Angioplasty, Balloon, Coronary; Arachidonic Acid; Aspirin; Case-Control Studies; Cell Adhesion Molecules; Clopidogrel; Drug Therapy, Combination; Female; Flow Cytometry; Humans; Lipopolysaccharide Receptors; Male; Microfilament Proteins; Middle Aged; Monocytes; P-Selectin; Phosphoproteins; Phosphorylation; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIb-IX Complex; Stents; Ticlopidine | 2009 |
Predictive value of post-treatment platelet reactivity for occurrence of post-discharge bleeding after non-ST elevation acute coronary syndrome. Shifting from antiplatelet resistance to bleeding risk assessment?
Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Biomarkers; Cell Adhesion Molecules; Clopidogrel; Coronary Artery Bypass; Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Hemorrhage; Humans; Intracranial Hemorrhages; Male; Microfilament Proteins; Middle Aged; Patient Discharge; Phosphoproteins; Phosphorylation; Pilot Projects; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Prospective Studies; Risk Assessment; Ticlopidine; Time Factors; Treatment Outcome | 2009 |
Effects of clopidogrel on "aspirin specific" pathways of platelet inhibition.
Topics: Adenosine Diphosphate; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Blood Platelets; Clopidogrel; Drug Interactions; Female; Humans; Male; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 2009 |
Platelet aggregability is modulated by eNOS locus in non-type 2 diabetic patients with acute coronary syndrome.
Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Alleles; Arachidonic Acid; Cohort Studies; Collagen; Diabetes Mellitus, Type 2; Endothelium, Vascular; Female; Genotype; Humans; Linear Models; Male; Middle Aged; Nitric Oxide Synthase Type III; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic | 2011 |
Comparison of the relative activities of inducing platelet apoptosis stimulated by various platelet-activating agents.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Apoptosis; Arachidonic Acid; Blood Platelets; Calcimycin; Caspases; Collagen; Enzyme Activation; Humans; Ionophores; Membrane Potential, Mitochondrial; Phosphatidylserines; Platelet Activation; Platelet Aggregation; Thrombin; Vasoconstrictor Agents | 2009 |
Measurement of platelet function in dogs using a novel impedance aggregometer.
Topics: Adenosine Diphosphate; Animals; Anticoagulants; Arachidonic Acid; Blood Platelets; Citric Acid; Collagen; Dogs; Electric Impedance; Female; Hirudins; Male; Peptide Fragments; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Reference Values; Reproducibility of Results; Sensitivity and Specificity | 2010 |
L-4F alters hyperlipidemic (but not healthy) mouse plasma to reduce platelet aggregation.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Adenosine Diphosphate; Animals; Apolipoprotein A-I; Apolipoproteins E; Arachidonic Acid; Blood Coagulation; Collagen; Dinoprostone; Disease Models, Animal; Hyperlipidemias; Injections, Subcutaneous; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Mimicry; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prostaglandin D2; Receptors, LDL; Thromboxane A2 | 2010 |
Measurement of platelet aggregation in ovine blood using a new impedance aggregometer.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Collagen; Dose-Response Relationship, Drug; Female; Fibrinolytic Agents; Hirudins; Male; Platelet Aggregation; Platelet Function Tests; Receptors, Thrombin; Reference Values; Ristocetin; Sheep | 2010 |
Platelet function recovery after cessation of aspirin: preliminary study of volunteers and surgical patients.
Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Arachidonic Acid; Aspirin; Blood Coagulation; Blood Platelets; Case-Control Studies; Drug Administration Schedule; Elective Surgical Procedures; Epinephrine; Female; Humans; International Normalized Ratio; Longitudinal Studies; Male; Middle Aged; Partial Thromboplastin Time; Pilot Projects; Platelet Aggregation; Platelet Aggregation Inhibitors; Predictive Value of Tests; Prospective Studies; Recovery of Function; Thromboxane B2; Time Factors; Young Adult | 2010 |
Evaluation of antiplatelet effects of a modified protocol by platelet aggregation in patients undergoing "one-stop" hybrid coronary revascularization.
Topics: Adenosine Diphosphate; Angioplasty, Balloon, Coronary; Arachidonic Acid; Aspirin; Clopidogrel; Combined Modality Therapy; Coronary Artery Bypass; Coronary Artery Disease; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Prospective Studies; Ticlopidine | 2010 |
In vitro inhibitory activities of Lauraceae aporphine alkaloids.
Topics: Adenosine Diphosphate; Alkaloids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aporphines; Arachidonic Acid; Circular Dichroism; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; In Vitro Techniques; Lauraceae; Lipoxygenase Inhibitors; Magnetic Resonance Spectroscopy; Plant Extracts; Plant Leaves; Platelet Activating Factor; Platelet Aggregation; Rabbits | 2010 |
The effect of menstrual cycle on platelet aggregation in reproductive-age women.
Topics: Acid Phosphatase; Adenosine Diphosphate; Adult; Arachidonic Acid; Case-Control Studies; Cohort Studies; Female; Follicular Phase; Humans; Isoenzymes; Luteal Phase; Male; Menstrual Cycle; Platelet Aggregation; Prospective Studies; Tartrate-Resistant Acid Phosphatase | 2010 |
Platelet activation patterns in platelet size sub-populations: differential responses to aspirin in vitro.
Topics: Acid Phosphatase; Adenosine Diphosphate; Arachidonic Acid; Aspirin; Blood Platelets; Cell Size; Cells, Cultured; Fibrinogen; Humans; Isoenzymes; P-Selectin; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Tartrate-Resistant Acid Phosphatase; Thromboxane B2; von Willebrand Factor | 2010 |
High on-treatment platelet reactivity by more than one agonist predicts 12-month follow-up cardiovascular death and non-fatal myocardial infarction in acute coronary syndrome patients receiving coronary stenting.
Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Arachidonic Acid; Cardiovascular Diseases; Chi-Square Distribution; Collagen; Drug Resistance; Drug Therapy, Combination; Female; Humans; Italy; Kaplan-Meier Estimate; Male; Middle Aged; Odds Ratio; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Prospective Studies; Recurrence; Risk Assessment; Risk Factors; Stents; Time Factors; Treatment Outcome | 2010 |
Development of a high-throughput ELISA assay for platelet function testing using platelet-rich plasma or whole blood.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Alprostadil; Antibodies, Monoclonal; Arachidonic Acid; Blood Platelets; Carrier Proteins; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Glycoproteins; High-Throughput Screening Assays; Humans; Immunoglobulins; Integrin alpha2; Integrin beta3; Observer Variation; P-Selectin; Peptides; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Reproducibility of Results; S-Nitroso-N-Acetylpenicillamine | 2010 |
Platelet aggregation responses vary over a period of time in healthy controls.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adult; Arachidonic Acid; Blood Platelets; Collagen; Female; Healthy People Programs; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Function Tests; Quality Control; Retrospective Studies; Ristocetin | 2010 |
[The role of prostaglandins in platelet aggregation in metabolic syndrome].
Topics: Adenosine Diphosphate; Arachidonic Acid; Blood Platelets; Collagen; Cyclic AMP; Epinephrine; Epoprostenol; Hemostasis; Humans; In Vitro Techniques; Metabolic Syndrome; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandins; Thromboxanes; von Willebrand Factor | 2010 |
Evaluation of platelet function and pharmacological platelet inhibition in patients with myeloproliferative disorders using multiple electrode aggregometry.
Topics: Adenosine Diphosphate; Adult; Aged; Arachidonic Acid; Aspirin; Austria; Case-Control Studies; Clopidogrel; Electrodes; Female; Humans; Linear Models; Male; Middle Aged; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Polycythemia Vera; Predictive Value of Tests; Reproducibility of Results; Thrombocythemia, Essential; Thrombosis; Ticlopidine; Treatment Outcome; Young Adult | 2010 |
Inhibitory effect of hericenone B from Hericium erinaceus on collagen-induced platelet aggregation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Arachidonic Acid; Basidiomycota; Biological Products; Blood Platelets; Collagen; Crotalid Venoms; Epinephrine; Humans; Indoles; Lectins, C-Type; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Signal Transduction; Thrombin; Thrombosis | 2010 |
Platelet reactivity and pregnancy loss.
Topics: Abortion, Habitual; Adenosine Diphosphate; Adult; Arachidonic Acid; Case-Control Studies; Collagen Type I; Dose-Response Relationship, Drug; Epinephrine; Female; Humans; Middle Aged; Peptide Fragments; Platelet Aggregation; Platelet Function Tests; Pregnancy; Pregnancy Trimester, First; Prospective Studies | 2010 |
Hemostatic function of buffy coat platelets in additive solution treated with pathogen reduction technology.
Topics: Adenosine Diphosphate; Arachidonic Acid; Blood Platelets; Blood Preservation; Blood Safety; Blood-Borne Pathogens; Centrifugation; Collagen; Fibrin; Hemostasis; Humans; Peptide Fragments; Pharmaceutical Solutions; Platelet Aggregation; Platelet Function Tests; Platelet Transfusion; Random Allocation; Riboflavin; Thrombelastography; Tissue Plasminogen Activator; Ultraviolet Rays | 2011 |
Does pioglitazone directly influence platelet aggregation?
Topics: Adenosine Diphosphate; Adult; Aged; Arachidonic Acid; Collagen; Diabetes Mellitus, Type 2; Epinephrine; Female; Humans; Hypoglycemic Agents; Male; Middle Aged; Pioglitazone; Platelet Aggregation; Thiazolidinediones | 2010 |
Effect of pioglitazone on platelet aggregation in a healthy cohort.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Blood Glucose; Chi-Square Distribution; Collagen; Diabetes Mellitus, Type 2; Epinephrine; Female; Humans; Hypoglycemic Agents; Lipids; Liver Function Tests; Male; Middle Aged; Pioglitazone; Platelet Aggregation; Prospective Studies; Thiazolidinediones | 2010 |
[Influence of new 1,3,4-thiadiazines on platelet aggregation in vitro and ex vivo].
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Drug Evaluation, Preclinical; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Thiadiazines | 2010 |
Effect of platelet turnover on whole blood platelet aggregation in patients with coronary artery disease.
Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Biomarkers; Blood Platelets; Case-Control Studies; Chi-Square Distribution; Collagen; Coronary Artery Disease; Denmark; Diabetes Mellitus, Type 2; Female; Humans; Linear Models; Male; Middle Aged; P-Selectin; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Platelet Function Tests; Registries; Risk Assessment; Risk Factors; Smoking; Thrombopoietin; Thromboxane B2 | 2011 |
Clopidogrel discontinuation and platelet reactivity following coronary stenting.
Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Arachidonic Acid; Aspirin; Clopidogrel; Collagen; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Epinephrine; Female; Humans; Ireland; Male; Middle Aged; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Prospective Studies; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 2011 |
Inhibitory effects of phylligenin and quebrachitol isolated from Mitrephora vulpina on platelet activating factor receptor binding and platelet aggregation.
Topics: Adenosine Diphosphate; Alkaloids; Animals; Annonaceae; Aporphines; Arachidonic Acid; Collagen; Humans; Inositol; Lignans; Platelet Aggregation; Platelet Membrane Glycoproteins; Protein Binding; Rabbits; Receptors, G-Protein-Coupled; Stigmasterol | 2010 |
Inconsistency of different methods for assessing ex vivo platelet function: relevance for the detection of aspirin resistance.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Aspirin; Blood Platelets; Collagen; Drug Resistance; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Thromboxane B2; Young Adult | 2010 |
In the presence of strong P2Y12 receptor blockade, aspirin provides little additional inhibition of platelet aggregation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adenosine Triphosphate; Arachidonic Acid; Aspirin; Collagen; Drug Synergism; Epinephrine; Humans; In Vitro Techniques; Peptide Fragments; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Thromboxane A2 | 2011 |
A highly constrained cyclic (S,S)-CDC- peptide is a potent inhibitor of carotid artery thrombosis in rabbits.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Animals; Arachidonic Acid; Bleeding Time; Blood Coagulation; Blood Platelets; Carotid Arteries; Carotid Artery Thrombosis; Collagen; Disease Models, Animal; Electric Stimulation; Eptifibatide; Humans; Male; Molecular Sequence Data; Peptides; Peptides, Cyclic; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Thrombosis | 2011 |
Statins have an early antiplatelet effect in patients with acute myocardial infarction.
Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Arachidonic Acid; Blood Platelets; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Function Tests; Pravastatin; Simvastatin | 2011 |
Platelet function testing in hirudin and BAPA anticoagulated blood.
Topics: Adenosine Diphosphate; Adult; Aged; Arachidonic Acid; Blood Platelets; Dipeptides; Female; Hirudins; Humans; Male; Platelet Aggregation Inhibitors; Platelet Function Tests; Sensitivity and Specificity; Sulfonamides | 2011 |
The periodontal anaerobe Porphyromonas gingivalis induced platelet activation and increased aggregation in whole blood by rat model.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Blood Platelets; Disease Models, Animal; Fibrinogen; Flow Cytometry; Humans; Male; P-Selectin; Periodontitis; Platelet Activation; Platelet Aggregation; Porphyromonas gingivalis; Rats; Rats, Wistar | 2011 |
BAPA, a synthetic dual inhibitor of Factor Xa and Thrombin, extends the storage-time to a maximum of 12 hours in ADP- and 24 hours in arachidonic acid-induced impedance aggregometry.
Topics: Adenosine Diphosphate; Adult; Anticoagulants; Arachidonic Acid; Blood Preservation; Citric Acid; Coagulants; Dipeptides; Factor Xa Inhibitors; Female; Humans; Male; Middle Aged; Platelet Aggregation; Sulfonamides; Thrombin; Young Adult | 2011 |
Role of iPLA(2) in the regulation of Src trafficking and microglia chemotaxis.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Biological Transport; Boron Compounds; Cell Line; Cell Membrane; Cell Surface Extensions; Chemotaxis; Endosomes; Enzyme Activation; Enzyme Inhibitors; Fluorescent Dyes; Focal Adhesions; Microglia; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phospholipases A2, Calcium-Independent; Recombinant Fusion Proteins; src-Family Kinases | 2011 |
Dual anticoagulant/antiplatelet persulfated small molecules.
Topics: Adenosine Diphosphate; Anticoagulants; Arachidonic Acid; Dose-Response Relationship, Drug; Humans; Molecular Weight; Platelet Aggregation; Platelet Aggregation Inhibitors; Sulfuric Acid Esters | 2011 |
Short-term exposure of platelets to glucose impairs inhibition of platelet aggregation by cyclooxygenase inhibitors.
Topics: Acetaminophen; Adenosine Diphosphate; Adult; Arachidonic Acid; Aspirin; Blood Platelets; Cells, Cultured; Collagen; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Female; Glucose; Humans; Indomethacin; Lactic Acid; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Platelet-Rich Plasma | 2011 |
Point-of-care assessment of platelet aggregation in paediatric open heart surgery.
Topics: Adenosine Diphosphate; Anesthesia; Arachidonic Acid; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Child; Child, Preschool; Cyanosis; Erythrocyte Transfusion; Female; Heart Defects, Congenital; Hemoglobins; Humans; Infant; Male; Peptide Fragments; Plasma; Platelet Aggregation; Platelet Count; Platelet Function Tests; Platelet Transfusion; Point-of-Care Systems; Prospective Studies | 2011 |
The relationship between platelet reactivity and infarct-related artery patency in patients presenting with a ST-elevation myocardial infarction.
Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Arachidonic Acid; Cohort Studies; Coronary Angiography; Female; Humans; Leukocyte Count; Male; Middle Aged; Myocardial Infarction; Platelet Activation; Prospective Studies; Risk Factors; Treatment Outcome; Vascular Patency | 2011 |
The antiplatelet activity of camel urine.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Blood Platelets; Camelus; Cattle; Dose-Response Relationship, Drug; Female; Humans; Lactation; Platelet Aggregation; Platelet Aggregation Inhibitors; Pregnancy; Urine | 2011 |
Comparison of venous and arterial blood sampling for the assessment of platelet aggregation with whole blood impedance aggregometry.
Topics: Adenosine Diphosphate; Arachidonic Acid; Area Under Curve; Arteries; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Electric Impedance; Female; Humans; Male; Phlebotomy; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Research Design; Specimen Handling; Ticlopidine; Veins | 2011 |
Platelet adhesion and degranulation induce pro-survival and pro-angiogenic signalling in ovarian cancer cells.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Apyrase; Arachidonic Acid; Cell Degranulation; Cell Survival; Drug Synergism; Epithelial-Mesenchymal Transition; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Neovascularization, Pathologic; Oligonucleotide Array Sequence Analysis; Ovarian Neoplasms; Peptide Fragments; Platelet Adhesiveness; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Receptors, Thrombin; Reproducibility of Results; Signal Transduction | 2011 |
Rapid degradation of cyclooxygenase-1 and hematopoietic prostaglandin D synthase through ubiquitin-proteasome system in response to intracellular calcium level.
Topics: Adenosine Diphosphate; Arachidonic Acid; Calcimycin; Calcium Ionophores; Calcium Signaling; Cell Line; Cyclooxygenase 1; Half-Life; Humans; Intramolecular Oxidoreductases; Leupeptins; Lipocalins; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Stability; Proteolysis; Ubiquitinated Proteins; Ubiquitination | 2012 |
Characterization of the in vivo antiplatelet activity of the antihypertensive agent losartan.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Antihypertensive Agents; Arachidonic Acid; Blood Coagulation; Carotid Artery Injuries; Losartan; Mice; Mice, Inbred C57BL; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptors, Thrombin; Receptors, Thromboxane A2, Prostaglandin H2; Thrombosis | 2012 |
Platelet reactivity in type 2 diabetes mellitus: a comparative analysis with survivors of myocardial infarction and the role of glycaemic control.
Topics: Adenosine Diphosphate; Adolescent; Adult; Aged; Aged, 80 and over; Arachidonic Acid; Aspirin; Blood Glucose; Blood Platelets; Collagen; Diabetes Mellitus, Type 2; Epinephrine; Female; Glycated Hemoglobin; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation; Severity of Illness Index; Survivors | 2012 |
Clinical outcomes using a platelet function-guided approach for secondary prevention in patients with ischemic stroke or transient ischemic attack.
Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; Brain Ischemia; Cerebral Hemorrhage; Clopidogrel; Female; Humans; Ischemic Attack, Transient; Kaplan-Meier Estimate; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Function Tests; Proportional Hazards Models; Secondary Prevention; Stroke; Survival Analysis; Ticlopidine; Treatment Outcome | 2012 |
Platelet-neutrophil aggregate formation in blood samples from dogs with systemic inflammatory disorders.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Blood Platelets; Collagen; Dog Diseases; Dogs; Epinephrine; Female; Flow Cytometry; Leukocytes, Mononuclear; Lipopolysaccharides; Male; Neutrophil Activation; Neutrophils; Platelet Aggregation; Prospective Studies; Statistics, Nonparametric; Systemic Inflammatory Response Syndrome; Tetradecanoylphorbol Acetate | 2012 |
Effect of different anticoagulants on multiple electrode platelet aggregometry after clopidogrel and aspirin administration in patients undergoing coronary stent implantation: a comparison between citrate and hirudin.
Topics: Adenosine Diphosphate; Aged; Analysis of Variance; Angioplasty, Balloon, Coronary; Anticoagulants; Arachidonic Acid; Aspirin; Citric Acid; Clopidogrel; Female; Hirudins; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Risk Factors; ROC Curve; Sensitivity and Specificity; Stents; Ticlopidine | 2013 |
BF066, a novel dual target antiplatelet agent without significant bleeding.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Arterioles; Chlorides; Collagen; Ferric Compounds; Fibrinogen; Hemorrhage; Humans; Immobilized Proteins; Mice; Mice, Inbred C57BL; Oligopeptides; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptor, Adenosine A2A; Thrombin; Thrombosis | 2012 |
In vitro platelet antiaggregatory properties of 4-methylcoumarins.
Topics: Adenosine Diphosphate; Anticoagulants; Arachidonic Acid; Aspirin; Collagen; Coumarins; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Humans; Molecular Structure; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptors, Thromboxane A2, Prostaglandin H2; Thromboxane-A Synthase; Umbelliferones | 2012 |
Hepatic mitochondrial dysfunction induced by fatty acids and ethanol.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Cell Line, Tumor; Cell Survival; Energy Metabolism; Ethanol; Fatty Liver; Humans; L-Lactate Dehydrogenase; Male; Membrane Potential, Mitochondrial; Mitochondria, Liver; Oxidation-Reduction; Oxidative Stress; Oxygen Consumption; Palmitic Acid; Rats; Rats, Wistar; Reactive Oxygen Species; Rotenone; Succinic Acid; Triglycerides; Uncoupling Agents | 2012 |
Clinical and biochemical aspirin resistance in patients with recurrent cerebral ischemia.
Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Brain Ischemia; Drug Resistance; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Recurrence; Specimen Handling; Treatment Failure | 2013 |
Postmenopausal women have an increased maximal platelet reactivity compared to men despite dual antiplatelet therapy.
Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Blood Platelets; Clopidogrel; Coronary Disease; Female; Humans; Male; Middle Aged; Peptide Fragments; Percutaneous Coronary Intervention; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Postmenopause; Prospective Studies; Sex Factors; Ticlopidine | 2012 |
Synthesis of novel indole hydrazone derivatives and evaluation of their antiplatelet aggregation activity.
Topics: Adenosine Diphosphate; Arachidonic Acid; Humans; Hydrazones; Indoles; Platelet Aggregation; Platelet Aggregation Inhibitors | 2013 |
One pot synthesis and biological activity evaluation of novel Schiff bases derived from 2-hydrazinyl-1,3,4-thiadiazole.
Topics: Adenosine Diphosphate; Anti-Bacterial Agents; Arachidonic Acid; Humans; Hydrazones; Microbial Sensitivity Tests; Mycobacterium bovis; Platelet Aggregation; Platelet Aggregation Inhibitors; Schiff Bases; Thiadiazoles | 2013 |
Assessment of high on-treatment platelet reactivity in patients with ischemic heart disease: concordance between the Multiplate and VerifyNow assays.
Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Blood Platelets; Clopidogrel; Drug Resistance; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Reproducibility of Results; Spain; Ticlopidine; Treatment Outcome | 2013 |
Abnormal whole blood thrombi in humans with inherited platelet receptor defects.
Topics: Adenosine Diphosphate; Adolescent; Arachidonic Acid; Base Sequence; Bernard-Soulier Syndrome; Blood Coagulation; Blood Platelets; Coagulants; DNA Mutational Analysis; Female; Humans; Male; Membrane Glycoproteins; Middle Aged; Molecular Sequence Data; Platelet Activation; Platelet Aggregation; Platelet Glycoprotein GPIb-IX Complex; Receptor, PAR-1; Ristocetin; Sequence Deletion; Thrombasthenia; Thrombelastography; Thrombin; Viscoelastic Substances; Young Adult | 2012 |
Hinokitiol inhibits platelet activation ex vivo and thrombus formation in vivo.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Blood Platelets; Calcium; Collagen; Gene Expression Regulation; Humans; Hydroxyl Radical; Mice; Mitogen-Activated Protein Kinases; Monoterpenes; Phospholipase C gamma; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Proto-Oncogene Proteins c-akt; Signal Transduction; Thrombin; Thrombosis; Tropolone | 2013 |
Inhibitory effects of in vivo oxidized high-density lipoproteins on platelet aggregation: evidence from patients with abetalipoproteinemia.
Topics: Abetalipoproteinemia; Adenosine Diphosphate; Adult; alpha-Tocopherol; Apolipoproteins B; Arachidonic Acid; Blood Platelets; Collagen; Fatty Acids, Unsaturated; Female; Humans; Lipoproteins, HDL; Malondialdehyde; Mutation; Oxidation-Reduction; Oxidative Stress; Platelet Aggregation; Scavenger Receptors, Class B; Young Adult | 2013 |
[The antiaggregant action of 2-morpholino-5-(thienyl-2)-6-H-1,3,4-thiadiazine in in vitro and ex vivo experiments].
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Blood Coagulation; Blood Coagulation Tests; Blood Platelets; Humans; Morpholines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Rabbits; Thiadiazines | 2013 |
Initial experiences with Multiplate® for rapid assessment of antiplatelet agent activity in neurosurgical emergencies.
Topics: Adenosine Diphosphate; Aged; Aged, 80 and over; Arachidonic Acid; Aspirin; Clopidogrel; Embolization, Therapeutic; Emergencies; Emergency Medical Services; Female; Hemostatic Techniques; Humans; Intracranial Hemorrhages; Male; Middle Aged; Neurosurgical Procedures; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Transfusion; Point-of-Care Systems; Ticlopidine | 2013 |
Inhibition of human platelet aggregation by eosinophils.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Blood Platelets; Chromatography, Gel; Collagen; Cytosol; Dextrans; Eosinophils; HL-60 Cells; Humans; Indomethacin; Male; Molecular Weight; NG-Nitroarginine Methyl Ester; Platelet Activating Factor; Platelet Aggregation; Rats; Rats, Wistar; Thrombin; Time Factors | 2013 |
Characterization of the aggregation responses of camel platelets.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Blood Platelets; Camelus; Clopidogrel; Collagen; Epinephrine; Female; Platelet Activation; Platelet Aggregation; Platelet Function Tests; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2; Ticlopidine | 2013 |
Stored platelet functionality is not decreased after warming with a fluid warmer.
Topics: Adenosine Diphosphate; Arachidonic Acid; Blood Platelets; Blood Preservation; Collagen; Confidence Intervals; Humans; Pilot Projects; Platelet Aggregation; Platelet Transfusion; Temperature; Thrombelastography | 2013 |
Antiplatelet loading improves behavioral outcome in a rabbit model of stroke.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Aspirin; Blood Platelets; Brain Ischemia; Collagen; Disease Models, Animal; Embolization, Therapeutic; Fibrinolytic Agents; Male; Platelet Aggregation Inhibitors; Rabbits; Random Allocation; Treatment Outcome | 2013 |
Effects of ex vivo platelet supplementation on platelet aggregability in blood samples from patients treated with acetylsalicylic acid, clopidogrel, or ticagrelor.
Topics: Adenosine; Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Peptide Fragments; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Transfusion; Ticagrelor; Ticlopidine | 2014 |
Changes in response to antiaggregatory treatment in patients with myeloproliferative neoplasms: a sequential study using multiple electrode aggregometry.
Topics: Adenosine Diphosphate; Adult; Aged; Arachidonic Acid; Aspirin; Blood Platelets; Case-Control Studies; Clopidogrel; Electrodes; Female; Hematologic Neoplasms; Humans; Male; Middle Aged; Myeloproliferative Disorders; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptors, Thrombin; Thrombosis; Ticlopidine; Treatment Outcome | 2013 |
Anti-platelet activity of a three-finger toxin (3FTx) from Indian monocled cobra (Naja kaouthia) venom.
Topics: Adenosine Diphosphate; Arachidonic Acid; Blood Platelets; Cells, Cultured; Clopidogrel; Elapid Venoms; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Thrombin; Ticlopidine | 2013 |
Response to antiplatelet therapy and platelet reactivity to thrombin receptor activating peptide-6 in cardiovascular interventions: Differences between peripheral and coronary angioplasty.
Topics: Adenosine Diphosphate; Aged; Angioplasty; Angioplasty, Balloon, Coronary; Arachidonic Acid; Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Monocytes; P-Selectin; Peptide Fragments; Percutaneous Coronary Intervention; Peripheral Arterial Disease; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prognosis; Stents; Ticlopidine | 2014 |
Multiobjective optimization on antiplatelet effects of three components combination by quantitative composition-activity relationship modeling and weighted-sum method.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Collagen; Drug Combinations; Drug Design; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Male; Platelet Aggregation Inhibitors; Quantitative Structure-Activity Relationship; Rabbits; Reproducibility of Results | 2014 |
Acquired thrombasthenia due to inhibitory effect of glycoprotein IIbIIIa autoantibodies.
Topics: Adenosine Diphosphate; Aged; Antibodies, Monoclonal, Murine-Derived; Arachidonic Acid; Autoantibodies; Blood Platelet Disorders; Collagen; Drug Monitoring; Female; Humans; Immunologic Factors; Lupus Erythematosus, Systemic; Platelet Aggregation; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Remission Induction; Ristocetin; Rituximab; Treatment Outcome | 2014 |
Acute fluctuation in blood glucose has no effect on platelet aggregation rate.
Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Adult; Aged; Arachidonic Acid; Blood Glucose; Cohort Studies; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Function Tests | 2014 |
[Antiaggregation activity of arachidonic acid conjugates with neurotropic peptides proglyprol and semax].
Topics: Adenosine Diphosphate; Adrenocorticotropic Hormone; Arachidonic Acid; Blood Platelets; Cells, Cultured; Drug Design; Epinephrine; Humans; Neuroprotective Agents; Oligopeptides; Peptide Fragments; Platelet Aggregation; Platelet Aggregation Inhibitors; Proline; Structure-Activity Relationship | 2014 |
N-substituted indole carbohydrazide derivatives: synthesis and evaluation of their antiplatelet aggregation activity.
Topics: Adenosine Diphosphate; Arachidonic Acid; Blood Platelets; Collagen; Humans; Hydrazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Quantitative Structure-Activity Relationship | 2014 |
Platelets from children are hyper-responsive to activation by thrombin receptor activator peptide and adenosine diphosphate compared to platelets from adults.
Topics: Adenosine Diphosphate; Adult; Aging; Arachidonic Acid; Blood Platelets; Cell Adhesion; Child; Humans; Hydrazones; Monocytes; Oligopeptides; P-Selectin; Piperazines; Platelet Activation; Receptors, Thrombin | 2015 |
Intraoperative changes in platelet function in relation to moderate haemorrhage.
Topics: Adenosine Diphosphate; Aged; Anticoagulants; Arachidonic Acid; Arthroplasty, Replacement, Hip; Blood Coagulation Tests; Blood Platelets; Collagen; Female; Hemorrhage; Humans; Intraoperative Period; Male; Middle Aged; Peptide Fragments; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies | 2015 |
Functional role of a polymorphism in the Pannexin1 gene in collagen-induced platelet aggregation.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adolescent; Adult; Alleles; Amino Acid Substitution; Animals; Arachidonic Acid; Cardiovascular Diseases; Collagen; Connexins; Gene Frequency; Genotype; Humans; Male; Mefloquine; Mice, Knockout; Nerve Tissue Proteins; Peptide Fragments; Platelet Aggregation; Polymorphism, Single Nucleotide; Probenecid; Purinergic P2X Receptor Antagonists; Recombinant Fusion Proteins; Signal Transduction; Transfection; Young Adult | 2015 |
Genome-wide association study of platelet aggregation in African Americans.
Topics: Adenosine Diphosphate; Adult; Alleles; Arachidonic Acid; Black or African American; Collagen; Epinephrine; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genome-Wide Association Study; Humans; Linkage Disequilibrium; Male; Middle Aged; Platelet Aggregation; Platelet Count; Polymorphism, Single Nucleotide; White People | 2015 |
Comparison of Aggregometry with Flow Cytometry for the Assessment of Agonists´-Induced Platelet Reactivity in Patients on Dual Antiplatelet Therapy.
Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; Drug Therapy, Combination; Flow Cytometry; Humans; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests | 2015 |
Comparison of aspirin and indobufen in healthy volunteers.
Topics: Adenosine Diphosphate; Adolescent; Adult; Aged; Arachidonic Acid; Aspirin; Blood Platelets; Cross-Over Studies; Drug Administration Schedule; Female; Healthy Volunteers; Humans; Isoindoles; Male; Middle Aged; Phenylbutyrates; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prostaglandin-Endoperoxide Synthases; Thromboxane B2 | 2016 |
Investigation of cyclooxygenase and signaling pathways involved in human platelet aggregation mediated by synergistic interaction of various agonists.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Cyclooxygenase Inhibitors; Humans; Inhibitory Concentration 50; Mitogen-Activated Protein Kinases; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Serotonin; Serotonin Antagonists; Signal Transduction; Type C Phospholipases; Young Adult | 2015 |
The effectiveness of platelet supplementation for the reversal of ticagrelor-induced inhibition of platelet aggregation: An in-vitro study.
Topics: Adenosine; Adenosine Diphosphate; Arachidonic Acid; Aspirin; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Transfusion; Ticagrelor | 2016 |
Low platelet activity predicts 30 days mortality in patients undergoing heart surgery.
Topics: Adenosine Diphosphate; Aged; Aortic Valve; Arachidonic Acid; Area Under Curve; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Erythrocyte Transfusion; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Prognosis; Retrospective Studies; Risk Factors; Survival Analysis; Thrombosis; Ticlopidine; Treatment Outcome | 2016 |
Acetylsalicylic acid resistance risk factors in patients with myocardial infarction.
Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; C-Reactive Protein; Drug Resistance; Female; Humans; Leukocyte Count; Male; Middle Aged; Myocardial Infarction; Natriuretic Peptide, Brain; Platelet Aggregation; Platelet Aggregation Inhibitors; Prevalence; Prospective Studies; Risk Factors | 2015 |
Hemocompatibility evaluation in vitro of methoxy polyethyleneglycol-polycaprolactone copolymer solutions.
Topics: Adenosine Diphosphate; Arachidonic Acid; Blood Coagulation; Cell Shape; Circular Dichroism; Complement Activation; Complement C3a; Erythrocytes; Fibrinogen; Hemolysis; Hemorheology; Humans; Kinetics; Materials Testing; Partial Thromboplastin Time; Platelet Aggregation; Polyesters; Polyethylene Glycols; Prothrombin Time; Solutions; Spectrometry, Fluorescence; Thrombelastography; Thromboxane B2 | 2016 |
Relationship between high on aspirin platelet reactivity and oxidative stress in coronary artery by-pass grafted patients.
Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Blood Platelets; Collagen; Coronary Artery Bypass; Coronary Artery Disease; Coronary Vessels; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Oxidative Stress; Platelet Aggregation; Platelet Aggregation Inhibitors; Thromboxane B2 | 2016 |
Comparison of common platelet receptors between the chacma baboon (Papio ursinus) and human for use in pre-clinical human-targeted anti-platelet studies.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Amino Acid Substitution; Animals; Arachidonic Acid; Blood Platelets; Drug Evaluation, Preclinical; Flow Cytometry; Humans; Male; Papio ursinus; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, Purinergic P2; Ristocetin | 2016 |
Aqueous extract of Rabdosia rubescens leaves: forming nanoparticles, targeting P-selectin, and inhibiting thrombosis.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Blood Coagulation; Blood Platelets; Chromatography, High Pressure Liquid; Cinnamates; Depsides; Flow Cytometry; Hydroxybenzoates; Isodon; Magnetic Resonance Spectroscopy; Male; Nanoparticles; P-Selectin; Plant Extracts; Plant Leaves; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Rosmarinic Acid; Spectrometry, Mass, Electrospray Ionization; Thrombin; Thrombosis | 2015 |
Dabigatran and rivaroxaban do not affect AA- and ADP-induced platelet aggregation in patients receiving concomitant platelet inhibitors.
Topics: Adenosine Diphosphate; Antithrombins; Arachidonic Acid; Clopidogrel; Dabigatran; Drug Therapy, Combination; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Rivaroxaban; Ticlopidine | 2016 |
[THE REFERENCE VALUES OF AGGREGATION OF PLATELETS IN ADULT POPULATION OF THE ASTRAKHAN OBLAST USING AGGREGOMETER MULTIPLATE].
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Blood Platelets; Electric Impedance; Female; Humans; Male; Platelet Aggregation; Receptors, Thrombin; Reference Values; Russia | 2016 |
Modulation of platelet functions by crude rice (Oryza sativa) bran policosanol extract.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Collagen; Dietary Fiber; Fatty Alcohols; Male; Oryza; Plant Extracts; Platelet Adhesiveness; Platelet Aggregation; Rats; Rats, Sprague-Dawley | 2016 |
Bioactive chemical constituents from the root bark of Morus australis.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Dose-Response Relationship, Drug; Flavonoids; Mice; Molecular Structure; Morus; Nitric Oxide; Plant Roots; Platelet Activating Factor; Platelet Aggregation; Rabbits; RAW 264.7 Cells; Structure-Activity Relationship | 2017 |
Tetraspanin Tspan9 regulates platelet collagen receptor GPVI lateral diffusion and activation.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Blood Platelets; Carrier Proteins; Cell Membrane; Gene Expression Regulation; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptides; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Membrane Glycoproteins; Primary Cell Culture; Protein Binding; Protein Transport; Signal Transduction; Tetraspanins | 2017 |
Evaluating platelet function disorders in children with bleeding tendency - A single center study.
Topics: Adenosine Diphosphate; Adolescent; Arachidonic Acid; Automation, Laboratory; Blood Platelets; Child; Child, Preschool; Epinephrine; Female; Hemorrhage; Humans; Infant; Infant, Newborn; Male; Platelet Aggregation; Platelet Function Tests; Retrospective Studies; Severity of Illness Index | 2017 |
The use of regression analysis in determining reference intervals for low hematocrit and thrombocyte count in multiple electrode aggregometry and platelet function analyzer 100 testing of platelet function.
Topics: Adenosine Diphosphate; Adolescent; Adult; Anemia; Arachidonic Acid; Automation, Laboratory; Blood Platelets; Case-Control Studies; Collagen; Female; Hematocrit; Humans; Male; Middle Aged; Pilot Projects; Platelet Aggregation; Platelet Function Tests; Point-of-Care Testing; Receptors, Thrombin; Reference Values; Regression Analysis; Thrombocytopenia | 2017 |
Glycated albumin modifies platelet adhesion and aggregation responses.
Topics: Adenosine Diphosphate; Arachidonic Acid; Blood Platelets; Calcium; Cells, Cultured; Epinephrine; Gene Expression Regulation; Glycated Serum Albumin; Glycation End Products, Advanced; Humans; Platelet Adhesiveness; Platelet Aggregation; Platelet Function Tests; Receptors, Adrenergic, alpha-1; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Receptors, Thromboxane A2, Prostaglandin H2; Serum Albumin | 2017 |
Evaluation of an automated light transmission aggregometry.
Topics: Adenosine Diphosphate; Adolescent; Adult; Arachidonic Acid; Automation, Laboratory; Blood Platelets; Collagen; Epinephrine; Female; Healthy Volunteers; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Function Tests; Platelet-Rich Plasma; Reproducibility of Results; Ristocetin | 2017 |
Platelet dysfunction in critically ill patients.
Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Blood Platelet Disorders; Critical Illness; Female; Humans; Male; Middle Aged; Platelet Function Tests; Retrospective Studies; Thrombelastography | 2017 |
Platelet reactivity in thromboelastometry. Revision of the FIBTEM test: a basic study.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Aspirin; Blood Coagulation Tests; Blood Platelets; Collagen; Cytochalasin D; Female; Fibrin; Fibrinogen; Humans; Integrin beta3; Male; Oligopeptides; Platelet Activation; Platelet Aggregation; Platelet Membrane Glycoprotein IIb; Primary Cell Culture; Thrombelastography | 2017 |
Synthesis, antiplatelet and antithrombotic activities of resveratrol derivatives with NO-donor properties.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Aspirin; Bleeding Time; Collagen; Fibrinolytic Agents; Hydrazones; Isosorbide Dinitrate; Male; Mice; Nitric Oxide Donors; Nitrites; Oxadiazoles; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats, Wistar | 2017 |
Anti-platelet effects of anti-glaucomatous eye drops: an in vitro study on human platelets.
Topics: Adenosine Diphosphate; Arachidonic Acid; Blood Platelets; Glaucoma; Humans; Mediator Complex; Ophthalmic Solutions; Platelet Activating Factor; Platelet Aggregation | 2017 |
Transfusion requirements in elective cardiopulmonary bypass surgery patients: predictive value of Multiplate and Thromboelastography (TEG) Platelet Mapping Assay.
Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; Blood Platelets; Cardiopulmonary Bypass; Coronary Artery Bypass; Elective Surgical Procedures; Female; Hemostasis; Humans; Intensive Care Units; Male; Middle Aged; Mitral Valve Annuloplasty; Platelet Aggregation; Platelet Function Tests; Platelet Transfusion; Prospective Studies; Thrombelastography; Transcatheter Aortic Valve Replacement | 2017 |
Intracellular origin and ultrastructure of platelet-derived microparticles.
Topics: Adenosine Diphosphate; Arachidonic Acid; Blood Platelets; Calcimycin; Calcium Ionophores; Cell-Derived Microparticles; Collagen; Flow Cytometry; Humans; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Platelet Activation; Thrombin | 2017 |
Thrombin-induced cytoskeleton dynamics in spread human platelets observed with fast scanning ion conductance microscopy.
Topics: Actin Cytoskeleton; Actins; Adenine; Adenosine Diphosphate; Arachidonic Acid; Benzyl Compounds; Blood Platelets; Cell Movement; Cytochalasin D; Dyneins; Epinephrine; Humans; Microscopy, Electrochemical, Scanning; Microtubules; Platelet Activation; Platelet Adhesiveness; Polymerization; Pseudopodia; Quinazolinones; Thrombin | 2017 |
Implementation of buffy-coat-derived pooled platelet concentrates for internal quality control of light transmission aggregometry: a proof of concept study.
Topics: Adenosine Diphosphate; Arachidonic Acid; Collagen; Humans; Oligopeptides; Platelet Aggregation; Platelet Function Tests; Proof of Concept Study; Quality Control; Reference Standards | 2017 |
Anti-platelet effects of vitamin supplements in age-related macular degeneration: an in vitro study.
Topics: Adenosine Diphosphate; Arachidonic Acid; Blood Platelets; Dietary Supplements; Healthy Volunteers; Humans; Inhibitory Concentration 50; Macular Degeneration; Platelet Activating Factor; Platelet Aggregation; Receptors, Thrombin; Vitamins | 2018 |
On-treatment platelet reactivity in peripheral and coronary blood in patients undergoing primary PCI for ST-segment elevation myocardial infarction (STEMI).
Topics: Adenosine Diphosphate; Arachidonic Acid; Aspirin; Blood Platelets; Coronary Vessels; Demography; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyridines; ST Elevation Myocardial Infarction | 2018 |
Inhibitory effects of luteolin‑4'‑O‑β‑D‑glucopyranoside on P2Y12 and thromboxane A2 receptor‑mediated amplification of platelet activation in vitro.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Arachidonic Acid; Bridged Bicyclo Compounds, Heterocyclic; Fatty Acids, Unsaturated; Female; Glucosides; Glycogen Synthase Kinase 3 beta; Hydrazines; Luteolin; Phosphatidylinositol 3-Kinases; Platelet Activation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Receptors, Purinergic P2Y12; Receptors, Thromboxane A2, Prostaglandin H2; rhoA GTP-Binding Protein; Serotonin; Signal Transduction; Thromboxane A2; Tritium | 2018 |
[Adjusting Platelet Counts for Platelet Aggregation Tests].
Topics: Adenosine Diphosphate; Adolescent; Adult; Arachidonic Acid; Collagen; Epinephrine; Humans; Middle Aged; Platelet Aggregation; Platelet Count; Platelet Function Tests; Ristocetin; Young Adult | 2018 |
[Synthesis and biological evaluation of novel chalcone aromatic oxygen alkyl acids compounds].
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Chalcones; Hyperlipidemias; Hypolipidemic Agents; Mice, Inbred C57BL; Oxygen; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrazines | 2016 |
Progranulin inhibits platelet aggregation and prolongs bleeding time in rats.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Bleeding Time; Hemostasis; Humans; Male; Partial Thromboplastin Time; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Progranulins; Prothrombin Time; Rats | 2018 |
Perhaps it's not the platelet: Ristocetin uncovers the potential role of von Willebrand factor in impaired platelet aggregation following traumatic brain injury.
Topics: Adenosine Diphosphate; Adult; Aged; Anti-Bacterial Agents; Arachidonic Acid; Brain Injuries, Traumatic; Case-Control Studies; Collagen; Factor VIII; Female; Humans; Male; Middle Aged; Peptide Fragments; Platelet Aggregation; Ristocetin; von Willebrand Factor; Young Adult | 2018 |
Effects of platelet dysfunction and platelet transfusion on outcomes in traumatic brain injury patients.
Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Arachidonic Acid; Blood Platelet Disorders; Brain Injuries, Traumatic; Female; Humans; Incidence; Male; Middle Aged; Platelet Transfusion; Prospective Studies; Thrombelastography; Tomography Scanners, X-Ray Computed; Treatment Outcome | 2018 |
Platelet aggregation response in immune thrombocytopenia patients treated with romiplostim.
Topics: Adenosine Diphosphate; Adult; Aged; Arachidonic Acid; Blood Platelet Disorders; Collagen; Epinephrine; Female; Humans; Male; Middle Aged; Platelet Aggregation; Purpura, Thrombocytopenic, Idiopathic; Receptors, Fc; Receptors, Thrombopoietin; Recombinant Fusion Proteins; Ristocetin; Thrombophilia; Thrombopoietin; Young Adult | 2019 |
Whole blood platelet aggregation determined by the ROTEM platelet equipment; reference intervals and stability.
Topics: Adenosine Diphosphate; Adult; Aged; Anticoagulants; Arachidonic Acid; Citric Acid; Female; Hirudins; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Function Tests; Receptors, Thrombin; Reference Values; Reproducibility of Results; Young Adult | 2020 |
Inhibition of Human Platelet Aggregation and Low-Density Lipoprotein Oxidation by
Topics: Adenosine Diphosphate; Arachidonic Acid; Blood Platelets; Flavonoids; Humans; Lamiaceae; Lipoproteins, LDL; Plant Extracts; Plant Leaves; Platelet Aggregation; Platelet Aggregation Inhibitors | 2019 |
Residual platelet reactivity is preferred over platelet inhibition rate in monitoring antiplatelet efficacy: insights using thrombelastography.
Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Blood Platelets; Clopidogrel; Cohort Studies; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Thrombelastography | 2020 |
Estimating short- and long-term reference change values and index of individuality for tests of platelet function.
Topics: Adenosine Diphosphate; Arachidonic Acid; Aspirin; Biological Variation, Population; Female; Follow-Up Studies; Hemorrhage; Humans; Male; Normal Distribution; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Reference Values; Thrombosis | 2019 |
Ticagrelor and prasugrel are independent predictors of improved long-term survival in ACS patients.
Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Cardiovascular Diseases; Clopidogrel; Dual Anti-Platelet Therapy; Female; Humans; Male; Middle Aged; Mortality; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Prognosis; Proportional Hazards Models; Prospective Studies; Secondary Prevention; Stroke; Survival Rate; Ticagrelor | 2020 |
Lower Platelet Aggregation Is a Risk Factor for Dual Antiplatelet Therapy-Associated Bleeding: A Preliminary Retrospective Study with Genotype Analysis.
Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Case-Control Studies; Dual Anti-Platelet Therapy; Female; Genotype; Glutathione S-Transferase pi; Hemorrhage; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIb-IX Complex; Polymorphism, Single Nucleotide; Receptors, Cell Surface; Retrospective Studies; Ticagrelor | 2020 |
Synergistic platelet inhibition between Omega-3 and acetylsalicylic acid dose titration; an observational study.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Aspirin; Drug Synergism; Drug Therapy, Combination; Fatty Acids, Omega-3; Humans; Male; Peptide Fragments; Platelet Aggregation; Platelet Aggregation Inhibitors; Young Adult | 2020 |
Platelets Selectively Regulate the Release of BDNF, But Not That of Its Precursor Protein, proBDNF.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Blood Platelets; Brain-Derived Neurotrophic Factor; Collagen; Female; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation; Protein Precursors; Secretory Pathway; Young Adult | 2020 |
Does the Degree of Platelet Adenosine Diphosphate and Arachidonic Acid Receptor Inhibition Correlate With the Severity of Injury in Non-Brain-Injured Trauma Patients?
Topics: Adenosine Diphosphate; Anticoagulants; Arachidonic Acid; Blood Platelets; Female; Humans; Injury Severity Score; Length of Stay; Linear Models; Male; Middle Aged; Receptors, Purinergic P1; Retrospective Studies; Thrombelastography; Wounds and Injuries | 2022 |
Rutin present in Alibertia edulis extract acts on human platelet aggregation through inhibition of cyclooxygenase/thromboxane.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Arachidonic Acid; Calcium; Collagen; Cyclooxygenase Inhibitors; Gene Expression Regulation; Humans; Plant Extracts; Plant Leaves; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Rubiaceae; Thromboxanes; Zebrafish | 2021 |
Impact of electric cardioversion on platelet activation.
Topics: Adenosine Diphosphate; Adult; Aged; Arachidonic Acid; Atrial Fibrillation; Blood Coagulation; Collagen; Electric Countershock; Female; Humans; Male; Middle Aged; Peptide Fragments; Platelet Activation; Platelet Aggregation; Platelet Factor 4; Platelet Function Tests; Ristocetin; Treatment Outcome | 2021 |
Traumatic brain injury patients with platelet inhibition receiving platelet transfusion demonstrate decreased need for neurosurgical intervention and decreased mortality.
Topics: Adenosine Diphosphate; Arachidonic Acid; Blood Platelet Disorders; Brain Injuries, Traumatic; Humans; Platelet Transfusion; Thrombelastography | 2022 |
Aspirin Administration Mitigates Platelet Hyperaggregability After Splenectomy in a Murine Model.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Aspirin; Blood Platelets; Disease Models, Animal; Mice; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Splenectomy | 2022 |
Serial assessment of thrombogenicity and hemodynamics in patients with type II diabetes in a clinical research unit: Evidence for circadian variations in clot formation.
Topics: Adenosine Diphosphate; Arachidonic Acid; Aspirin; Blood Pressure; Circadian Rhythm; Diabetes Mellitus, Type 2; Humans; Thrombosis | 2022 |
Platelet function testing using the Multiplate analyzer after administration of aspirin in Aachen minipigs.
Topics: Adenosine; Adenosine Diphosphate; Animals; Arachidonic Acid; Aspirin; Blood Platelets; Diphosphates; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Receptors, Thrombin; Swine; Swine, Miniature | 2022 |
Platelet dysfunction persists after trauma despite balanced blood product resuscitation.
Topics: Adenosine Diphosphate; Arachidonic Acid; Blood Platelets; Cohort Studies; Collagen; Humans; Platelet Function Tests; Receptors, Thrombin; Retrospective Studies; Ristocetin | 2023 |
Effects of platelets activated by different agonists on fibrin formation and thrombin generation.
Topics: Adenosine Diphosphate; Arachidonic Acid; Blood Platelets; Calcimycin; Collagen; Fibrin; Humans; Phosphatidylserines; Thrombin | 2023 |
Plasma Concentration of Cortisol Negatively Associates with Platelet Reactivity in Older Subjects.
Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; Blood Platelets; Collagen; Humans; Hydrocortisone; Platelet Aggregation; Platelet Aggregation Inhibitors | 2022 |
Platelet Aggregation in Apparently Healthy Elderly Populations: Reference Ranges and Influence of Hematology Parameters.
Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; Female; Hematology; Humans; Male; Platelet Aggregation; Platelet Count; Platelet Function Tests; Reference Values | 2023 |
Development of a Novel Apigenin Dosage form as a Substitute for the Modern Triple Antithrombotic Regimen.
Topics: Adenosine Diphosphate; Animals; Apigenin; Arachidonic Acid; Cardiovascular Diseases; Fibrinolytic Agents; Mice; Mice, Inbred C57BL; Olive Oil; Platelet Aggregation; Platelet Aggregation Inhibitors | 2023 |
Multicenter evaluation of light transmission platelet aggregation reagents: communication from the ISTH SSC Subcommittee on Platelet Physiology.
Topics: Adenosine Diphosphate; Arachidonic Acid; Blood Platelets; Communication; Epinephrine; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Reproducibility of Results; Ristocetin | 2023 |