adenosine diphosphate has been researched along with apyrase in 310 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 66 (21.29) | 18.7374 |
| 1990's | 78 (25.16) | 18.2507 |
| 2000's | 97 (31.29) | 29.6817 |
| 2010's | 62 (20.00) | 24.3611 |
| 2020's | 7 (2.26) | 2.80 |
| Authors | Studies |
|---|---|
| Chao, FC; Conneely, GS; Lawler, JW; Tullis, JL | 1 |
| Lewis, GP; Lieberman, GE; Peters, TJ | 1 |
| Blondowska, D; Cazenave, JP; Kinlough-Rathbone, RL; Mustard, JF; Packham, MA; Richardson, M | 1 |
| Boyd, J; Kindness, G; Long, WF; Williamson, FB | 1 |
| Cohen, I; Glaser, T; Kaminski, E | 1 |
| Lewis, GP; Lieberman, GE; Westwick, J | 1 |
| Fujitani, B; Shimizu, M; Tsuboi, T; Yoshida, K | 1 |
| Kindness, G; Long, WF; Williamson, FB | 1 |
| Nunn, B | 1 |
| Lefort, J; Vargaftig, BB | 1 |
| Holme, R; Hovig, T; Oftebro, R | 1 |
| Holme, S; Holmsen, H; Sixma, JJ; Wester, J | 1 |
| Ts'ao, C | 1 |
| Konstantinov, YM; Lyakhovich, VV; Panov, AV | 1 |
| Borgers, M; De Clerck, F; de Gaetano, G; Vermylen, J | 1 |
| Lieberman, GE; Nath, N; Niewiarowski, S; Sha, AT; Stewart, GJ | 1 |
| Arfors, KE; Bergquist, D; Born, GV | 1 |
| Carroll, RC; Rubinstein, E; Urso, I | 1 |
| Penny, WF; Ware, JA | 1 |
| Bakker, WW; Baller, JF; Hardonk, MJ; Heynen, ER; Poelstra, K | 1 |
| Boucheix, C; Carroll, RC; Rubinstein, E; Urso, I | 1 |
| Battastini, AM; Dias, RD; Rocha, JB; Sarkis, JJ | 1 |
| Endris, R; Endris, TM; Ribeiro, JM | 1 |
| Abi-Younes, SA; Ayers, ML; Myers, AK | 1 |
| Anderson, HV; Benedict, CR; Buja, LM; Campbell, WB; Cui, K; Maffrand, JP; McNatt, J; Ober, JC; Rosolowsky, M; Yao, SK | 1 |
| Ballon, BC; Gerrard, JM; Greenberg, AH; Spearman, MA; Wright, JA | 1 |
| Barcellos, CK; Battastini, AM; da Rocha, JB; Dias, RD; Sarkis, JJ | 1 |
| DeCenzo, MT; Kang, J; Saitoh, M; Slayter, HS; Smith, M; Ware, JA; Watkins, SC | 1 |
| Broekman, MJ; Eiroa, AM; Hajjar, KA; Islam, N; Marcus, AJ; Safier, LB; Ullman, HL | 1 |
| Bakker, WW; Baller, JF; Hardonk, MJ; Poelstra, K | 1 |
| Deguchi, K; Matsumoto, T; Okano, K; Sugiyama, Y | 1 |
| Bourchier, RG; Gloviczki, P; Komori, K; Miller, VM; Vanhoutte, PM | 1 |
| Asai, T; Suzuki, Y | 1 |
| Dias, RD; Mello, CF; Rocha, JB; Sarkis, JJ | 1 |
| Akada, S; Hisanaga, H; Ichijo, M; Iioka, H; Morimoto, K; Moriyama, I | 1 |
| Jesty, J | 1 |
| Vrbjar, N; Ziegelhoffer, A | 1 |
| Prosdocimi, M; Zatta, A | 1 |
| Coade, SB; Pearson, JD | 1 |
| Akasaki, M; Hisanaga, H; Ichijo, M; Iioka, H; Katakami, Y; Katoh, Y; Moriyama, I; Nabuchi, K | 1 |
| Dionigi, P; Fratino, P; Grignani, G; Jemos, V; Pacchiarini, L; Ricetti, MM; Zucchella, M | 1 |
| Angel, JL; Benoit, R; Bruce, A; Knuppel, RA; O'Brien, WF; Saba, HI | 1 |
| Arai, Y; Hirota, K; Miura, Y; Yagi, K | 1 |
| Lüthje, J; Ogilvie, A; Schomburg, A | 1 |
| Belzer, I; Friedberg, I; Huang, NN; Lane, E; Lustig, KD; Weisman, GA | 1 |
| Ribeiro, JM; Rossignol, PA; Spielman, A | 1 |
| Barzaghi, G; Cerletti, C; de Gaetano, G | 1 |
| Born, GV; Cusack, NJ; Kakkar, A; McClure, MO | 1 |
| Cerbone, AM; Cirillo, F; Di Minno, G; Mancini, M; Mattioli, PL; Pannain, M; Postiglione, A | 1 |
| Coller, BS | 2 |
| Grazi, E; Lanzara, V; Magri, E | 1 |
| Baum, H; Coade, SB; Cook, ND; Dawson, JM; Peters, TJ | 1 |
| Guimarães, JA; Ribeiro, JM; Sarkis, JJ | 1 |
| Bakker, WW; Donga, J; Hardonk, MJ; Hulstaert, CE; Willink, EJ | 1 |
| Bellucci, S; Bryckaert, MC; Calvo, F; Camez, A; Dupuy, E; Tobelem, G | 1 |
| Connellan, JM; Louis, CJ; Scarlett, JD; Thurlow, PJ | 1 |
| Ardlie, NG; Bell, LK; Garrett, JJ | 1 |
| Carruthers, A; Hebert, DN | 1 |
| Grabarek, J; Hawiger, J; Kloczewiak, M; Timmons, S | 1 |
| Esumi, N; Imashuku, S; Todo, S | 1 |
| Harfenist, EJ; Mustard, JF; Packham, MA | 2 |
| Carter, AJ; Heptinstall, S | 1 |
| Peters, TJ; Smith, GD; Smith, GP | 1 |
| Emms, H; Lewis, GP | 1 |
| Isler, RE; Knowles, AF; Reece, JF | 1 |
| Baum, H; Montague, DJ; Peters, TJ | 1 |
| Belisario, A; Modiano, A | 1 |
| Frojmovic, MM; Milton, JG | 1 |
| Catalano, PM; De Marco, L; Di Minno, G; Murphy, S; Shapiro, SS | 1 |
| Castella, A; Kupinski, JM; Miller, JL; Ruggeri, ZM | 1 |
| Rittenhouse, SE | 1 |
| Broekman, MJ; Kaplan, KL; Marcus, AJ; Safier, LB; Ullman, HL; Weksler, BB; Wong, KT | 1 |
| Ernst, M; Fischer, H; Hovestadt, I; Kato, T; Rietschel, E; Schöpf, E; Wokalek, H | 1 |
| Egan, JJ; Grant, RA; Johnson, MM; Peerschke, EI; Zucker, MB | 1 |
| Harfenist, EJ; Mustard, JF; Packham, MA; Raychaudhuri, G | 1 |
| Hallam, TJ; Scrutton, MC; Wallis, RB | 1 |
| High, JA; Namm, DH | 1 |
| Bastida, E; Jamieson, GA; Ordinas, A | 1 |
| Kondo, T; Muramatsu, N | 1 |
| Peerschke, EI; Zucker, MB | 1 |
| Arfors, KE; Bergqvist, D | 1 |
| Cook, GM; Masters, VM; Webster, J | 1 |
| Cupp, EW; Cupp, MS; Moulton, JK; Ochoa-A, JO | 1 |
| Corrie, JE; Ferenczi, MA; Reid, GP; Thirlwell, H; Trentham, DR | 1 |
| Bakker, WW; Cheung, PK; Visser, J | 1 |
| Dias, RD; Frassetto, SS; Sarkis, JJ | 2 |
| Blaes, N; Covacho, C | 1 |
| Barsotti, RJ; Martin, H | 1 |
| Barcellos, CK; Battastini, AM; Dias, RD; Sarkis, JJ; Schetinger, MR; Silva, LB | 1 |
| Cupp, EW; Cupp, MS; Ramberg, FB | 1 |
| Fuglsang, A; Khromov, A; Somlyo, AP; Somlyo, AV; Török, K | 1 |
| Alvarez, A; Aranda, E; Banda, A; Chayet, L; Chiong, M; Collados, L; Kettlun, AM; Mancilla, M; Quintar, R; Valenzuela, MA | 1 |
| Cecchi, E; Failli, P; Fazzini, A; Giotti, A; Ruocco, C | 1 |
| Lind, SE; Vasconcellos, CA | 1 |
| Bakker, WW; Faas, MM; Schuiling, GA; Visscher, CA | 1 |
| Grevelink, SA; Lerner, EA; Loscalzo, J; Youssef, DE | 1 |
| Feijge, MA; Heemskerk, JW; Hoyland, J; Mason, WT; Sage, SO; Vis, P | 1 |
| Ferreira, ST; Meirelles, MN; Nascimento, PS; Vasconcelos, EG; Verjovski-Almeida, S | 1 |
| Caparrotta, L; Dejana, E; Del Maschio, A; Pandolfo, L; Prosdocimi, M; Zatta, A | 1 |
| Haimovich, B; Ji, P; Kaneshiki, N | 1 |
| Broekman, MJ; Fliessbach, JH; Hajjar, KA; Islam, N; Jendraschak, E; Kaminski, WE; Marcus, AJ; Safier, LB; Silverstein, RL; von Schacky, C | 1 |
| MacKenzie, AB; Mahaut-Smith, MP; Sage, SO | 1 |
| Beaudoin, AR; D'Orléans-Juste, P; Picher, M; Sévigny, J | 1 |
| Pérez de León, AA; Tabachnick, WJ | 1 |
| Dzurba, A; Vrbjar, N; Ziegelhöffer, A | 1 |
| Caprino, L; Stella, C; Togna, AR; Togna, G | 1 |
| Meghji, P; Pearson, JD; Slakey, LL | 1 |
| Bach, FH; Candinas, D; Hancock, WW; Koyamada, N; Miyatake, T; Robson, SC; Siegel, J | 1 |
| Evans, RJ; Heath, MF; Jarvis, GE | 1 |
| Bach, FH; Candinas, D; Hancock, WW; Hechenleitner, P; Koyamada, N; Miyatake, T; Robson, SC; Siegel, J | 1 |
| Bach, FH; Candinas, D; Hancock, WW; Kaczmarek, E; Koziak, K; Millan, M; Robson, SC; Siegel, JB | 1 |
| Chang, YL; Hsu, FL; Kang, YF; Ko, FN; Teng, CM; Yang, SC | 1 |
| Bianco, AR; Caraglia, M; Correale, P; Giuliano, M; Guarrasi, R; Marinetti, MR; Procopio, A; Tagliaferri, P | 1 |
| Lages, B; Weiss, HJ | 2 |
| Battastini, AM; Bonan, CD; Dias, RD; Frassetto, SS; Moreira, CM; Sarkis, JJ; Schetinger, MR | 1 |
| Horiuti, K; Takemori, S; Yagi, N | 1 |
| Mezzasoma, I; Minelli, A; Moroni, M; Trinari, D | 1 |
| Clifford, EE; Dalal, P; Dubyak, GR; Martin, KA; Thomas, R | 1 |
| Feijge, MA; Heemskerk, JW; Hemker, HC; Henneman, L; Rosing, J | 1 |
| De Leon-Fernandez, M; Dutcher, JP; Lalezari, P; Mrowiec, ZR; Oleksowicz, L; Puszkin, EG | 1 |
| Gómez de Aranda, I; Martí, E; Solsona, C | 1 |
| Ferreira, ST; Torres, CR; Vasconcelos, EG; Verjovski-Almeida, S | 1 |
| Alyonycheva, TN; Brasel, K; Broekman, MJ; Caspary, RG; Drosopoulos, JH; Gayle, RB; Gimpel, SD; Islam, N; Maliszewski, CR; Marcus, AJ; Price, V; Richards, C; Schoenborn, MA | 1 |
| Housley, GD; Kendrick, IS; Muñoz, DJ; Thorne, PR; Vlajkovic, SM | 1 |
| Gaspar, AR; Louw, AI; Mans, BJ; Neitz, AW | 1 |
| Aoki, T; Honda, S; Okubo, M; Seki, J; Senzaki, K; Takahashi, F; Takasugi, H; Tanaka, A; Tomiyama, Y | 1 |
| Maeda, M; Nagashima, S; Nakashima, A; Sakura, H | 1 |
| Adachi, M; Ikeda, Y; Kondo, K; Nakashima, M; Saniabadi, AR; Suzuki, Y; Umemura, K | 1 |
| Falquembach, F; Mezzomo, A; Michelot, F; Rocha, JB; Schetinger, MR | 1 |
| Martinson, EA; Marx-Grunwitz, A; Presek, P; Scheible, S | 1 |
| Reimann, S; Schrör, K; Weber, AA | 1 |
| Knowles, AF; Nagy, AK | 1 |
| Kinlough-Rathbone, RL; Packham, MA; Perry, DW; Rand, ML | 1 |
| Guo, ZG; Yi, FX | 1 |
| Ford, JE; Mulero, JJ; Nelken, ST; Yeung, G | 1 |
| Zimmermann, H | 1 |
| Csizmadia, E; Goepfert, C; Guckelberger, O; Imai, M; Kaczmarek, E; Koziak, K; Robson, SC; Schulte Am Esch, J; Sévigny, J | 1 |
| Kaczmarek, E; Koziak, K; Robson, SC; Sévigny, J; Siegel, JB | 1 |
| Hayakawa, T; Ishii-Watabe, A; Mizuguchi, H; Uchida, E | 1 |
| Espinosa, V; Kettlun, AM; Valenzuela, MA; Zanocco, A | 1 |
| Belisario, MA; Della Morte, R; Di Domenico, C; Lucisano, A; Squillacioti, C; Staiano, N; Tafuri, S | 1 |
| Bittencourt, S; Bonacorso, HG; da Rocha, JB; Moretto, MB; Moro, F; Morsch, VM; Neis, RT; Porto, NM; Schetinger, MR; Vieira, V; Zanatta, N | 1 |
| Kawashima, Y; Nagasawa, T; Ninomiya, H | 1 |
| Retzer, M; Siess, W; Watson, SP; Wilde, JI | 1 |
| Bajwa, SS; Ford, JE; McGowan, DW; Mulero, JJ; Yeung, G | 1 |
| Lapinski, PE; Neubig, RR; Raghavan, M | 1 |
| Beigi, RD; Dubyak, GR | 1 |
| Henttinen, T; Jalkanen, S; Yegutkin, GG | 1 |
| Camerini, D; Gear, AR; Polanowska-Grabowska, RK; Raha, S; Suttitanamongkol, S; Viisoreanu, D | 1 |
| Baurand, A; Bourguignon, JJ; Cazenave, JP; Freund, M; Gachet, C; Léon, C; Raboisson, P | 1 |
| Braun, N; Heine, P; Robson, SC; Servos, J; Sévigny, J; Zimmermann, H | 1 |
| Guo, X; Guo, ZG; Huang, SL; Sun, P; Yi, FX | 1 |
| Chen, W; Guidotti, G | 1 |
| Balz, D; Morsch, VM; Schetinger, MR; Vieira, VL | 1 |
| Dardik, R; Frojmovic, M; Savion, N; Shenkman, B; Tamarin, I; Varon, D | 1 |
| Hicks-Berger, CA; Kirley, TL; Smith, TM; Yang, F | 1 |
| Ferreira, ST; Martins, SM; Torres, CR | 1 |
| Caprino, L; Togna, AR; Togna, GI | 1 |
| Bogo, MR; Bonan, CD; Borges, FP; da Graça Fauth, M; de Aguiar Matos, JA; De Carli, GA; Dias, RD; Tasca, T | 1 |
| Bültmann, R; Starke, K | 1 |
| Battastini, AM; Bonan, CD; Kirchner, SM; Sarkis, JJ | 1 |
| Atkinson, BT; Pears, CJ; Stafford, MJ; Watson, SP | 1 |
| Battastini, AM; Berti, SL; Bonan, CD; da Silva, FL; Sarkis, JJ; Wannmacher, CM | 1 |
| Boeck, CR; Sarkis, JJ; Vendite, D | 1 |
| Grinthal, A; Guidotti, G | 1 |
| Coimbra, ES; Corte-Real, S; De Freitas, FG; Durão, AC; Gonçalves-da-Costa, SC; Silva-Santos, MI; Souza, CS; Vasconcelos, EG | 1 |
| Gomez, FA; Kaddis, J; Silverio, C; Zhang, Y; Zurita, C | 1 |
| Battastini, AM; Bonan, CD; Bruno, AN; Sarkis, JJ; Wofchuk, ST | 1 |
| Balduini, CL; Dunzendorfer, S; Egger, P; Gritti, D; Kaneider, NC; Noris, P; Ricevuti, G; Wiedermann, CJ | 1 |
| Drosopoulos, JH | 1 |
| Birk, AV; Broekman, MJ; Drosopoulos, JH; Gladek, EM; Marcus, AJ; Robertson, HD; Szeto, HH | 1 |
| Balduini, C; Barberis, L; Hirsch, E; Lova, P; Paganini, S; Sinigaglia, F; Torti, M; Wymann, M | 1 |
| Becker, BF; Bolz, SS; Gloe, T; Keller, M; Krötz, F; Pohl, U; Sohn, HY | 1 |
| Balz, D; da Silva, AC; de Souza Wyse, AT; Morsch, AL; Morsch, VM; Schetinger, MR; Vieira, VL | 1 |
| Demenis, MA; Furriel, RP; Leone, FA | 1 |
| Cardemil, E; Espinosa, V; Kettlun, AM; Valenzuela, MA; Zanocco, A | 1 |
| Beaudoin, AR; Bkaily, G; D' Orléans-Juste, P; Duval, M; Gendron, FP | 1 |
| Battastini, AM; Berti, SL; Bonan, CD; Kirst, IB; Oses, JP; Rücker, B; Sarkis, JJ | 1 |
| Battastini, AM; Böhmer, AE; Crema, L; Dalmaz, C; Ferreira, MB; Fürstenau, CR; Sarkis, JJ; Torres, IL | 1 |
| Battastini, AM; Bonan, CD; Borges, FP; De Carli, GA; Sarkis, JJ; Tasca, T | 1 |
| Banjac, A; Horvat, A; Nedeljkovic, N; Nikezic, G; Stojiljkovic, M | 1 |
| Broekman, MJ; Drosopoulos, JH; Islam, N; Levi, R; Marcus, AJ; Pinsky, DJ; Sesti, C | 1 |
| Enjyoji, K; Guckelberger, O; Imai, M; Kaczmarek, E; Kruskal, JB; Robson, SC; Sévigny, J; Sun, XF | 1 |
| D'Souza-Ault, M; Faudry, E; Felix, CR; Kieffer, S; Lozzi, SP; Ricart, CA; Santana, JM; Sousa, MV; Teixeira, AR; Vernet, T | 1 |
| Adinolfi, E; Baricordi, OR; Chiozzi, P; Di Virgilio, F; Morelli, A; Rizzo, R; Solini, A | 1 |
| Lunkes, DS; Lunkes, GI; Mazzanti, CM; Miron, VR; Morsch, AL; Morsch, VM; Schetinger, MR | 1 |
| Alonso, M; Amos, LA; Cross, RA; Hirose, K; Löwe, J | 1 |
| Battastini, AM; Pochmann, D; Rücker, B; Sarkis, JJ | 1 |
| Barth, A; Liu, M | 1 |
| Casali, EA; Lara, DR; Leke, R; Oses, JP; Portela, LV; Sarkis, JJ; Schmidt, AP; Souza, DO; Wofchuk, S | 1 |
| Battastini, AM; Buffon, A; Fürstenau, CR; Ribeiro, VB; Sarkis, JJ | 1 |
| Erlinge, D; Götberg, M; Olivecrona, G; Olsson, ML; Wang, L; Winzell, MS | 1 |
| Bittencourt, FP; da Silva, JE; Leal, CA; Leal, DB; Morsch, VM; Neu, TN; Schetinger, MR; Streher, CA | 1 |
| Barth, A; Karjalainen, EL; Liu, M | 1 |
| Barreto-Chaves, ML; Bonan, CD; Bruno, AN; Diniz, GP; Pochmann, D; Ricachenevsky, FK; Sarkis, JJ | 1 |
| Broekman, MJ; Drosopoulos, JH; Islam, N; Levi, R; Marcus, AJ; Olson, KE; Pinsky, DJ | 1 |
| Friedman, C; Laties, AM; Lu, W; McGlinn, A; Mitchell, CH; Pendrak, K; Reigada, D; Stone, RA; Zhang, X | 1 |
| Lindahl, TL; Mattsson, C; Nylander, S | 1 |
| Fachinetto, R; Nogueira, CW; Rocha, JB; Savegnago, L | 1 |
| Alderete, JF; Bonan, CD; De Carli, GA; Sarkis, JJ; Tasca, T | 1 |
| Ali, NM; Broekman, MJ; Buergler, JM; Kaluza, GL; Kleiman, NS; Maliszewski, CR; Marcus, AJ; Raizner, AE; Schulz, DG | 1 |
| Hildebrandt, C; Horner, S; Kassack, MU; Lambrecht, G; Mahaut-Smith, MP; Menke, K; Nickel, P; Ullmann, H | 1 |
| Böhmer, AE; Nejar Bruno, A; Pochmann, D; Sarkis, JJ | 1 |
| Casali, EA; Chiarelli, RA; Henz, SL; Ribeiro, CG; Rosa, A; Sarkis, JJ | 1 |
| Barreto-Chaves, ML; Carneiro-Ramos, MS; Cotomacci, G; Júnior, MB; Sarkis, JJ | 1 |
| Ferraro, RB; Fonseca de Souza, AL; Gomes, MT; Lopes, AH; Martins-Duarte, ES; Meyer-Fernandes, JR; Pinheiro, CM; Santos, AL; Vannier-Santos, MA | 1 |
| Chaikof, EL; Cui, W; Haller, CA; Robson, SC; Wen, J | 1 |
| Bjelobaba, I; Lavrnja, I; Nedeljkovic, N; Pekovic, S; Rakic, L; Stojiljkovic, M; Stojkov, D; Subasic, S; Vjestica, A | 1 |
| Banjac, A; Demajo, M; Horvat, A; Momić, T; Orlić, T; Petrović, S | 1 |
| Gao, ZG; Jacobson, KA; Mamedova, LK | 1 |
| Barreto-Chaves, ML; Bruno, AN; Casali, EA; Corbelini, PF; Diniz, GP; Pessoa-Pureur, R; Sarkis, JJ; Silva, FR; Zamoner, A | 1 |
| Calatzis, A; Losonczy, H; Penz, S; Siess, W; Tóth, O | 1 |
| Dai, L; Han, Y; Lu, XX; Ruan, CG; Shen, WH; Wang, ZY; Wu, DP | 1 |
| Dailey, ME; Kurpius, D; Nolley, EP | 1 |
| Delwing, D; Sarkis, JJ; Wyse, AT | 1 |
| Ballard, HS; Broekman, MJ; Furman, RR; Islam, N; Marcus, AJ; Olson, AE; Olson, KE; Pulte, D | 1 |
| Cattaneo, M; Lecchi, A; Lussana, F; Zighetti, ML | 1 |
| Alves, EW; Teixeira-Ferreira, A | 1 |
| Bowser, DN; Khakh, BS | 1 |
| Bauchspiess, K; da Silva, JE; Leal, CA; Leal, DB; Maldonado, PA; Morsch, VM; Schetinger, MR; Schrekker, CM | 1 |
| Barat, C; Beaudoin, AR; Martin, G; Sévigny, J; Tremblay, MJ | 1 |
| Bigonnesse, F; Lavoie, EG; Lecka, J; Lévesque, SA; Sévigny, J | 1 |
| Asada, Y; Fujimura, Y; Furukoji, E; Matsumoto, M; Tamura, S; Tanaka, N; Yamamoto, R; Yamashita, A | 1 |
| Kauffenstein, G; Kukulski, F; Lavoie, EG; Lecka, J; Legendre, C; Lévesque, SA; Munkonda, MN; Pelletier, J; Sévigny, J | 1 |
| Ajayi, AA; Cooper, J; Horn, EH; Pharmacols, FB; Rubin, PC | 1 |
| Fox, SC; Glenn, JR; Heptinstall, S; Johnson, AJ; Myers, B; White, AE | 1 |
| Chiang, WC; Knowles, AF | 1 |
| Beddoe, T; Byres, E; Cowan, PJ; d'Apice, AJ; Dunstone, MA; Hartland, EL; Müller, CE; Newton, HJ; Riedmaier, P; Robson, SC; Rossjohn, J; Sansom, FM; Stephan, H | 1 |
| Craig, R; Padrón, R; Zhao, FQ | 1 |
| Araújo, Mdo C; Becker, L; Corrêa, M; Leal, D; Lunkes, DS; Lunkes, GI; Morsch, VM; Rosa, CS; Schetinger, MR | 1 |
| Boehm, S; Chandaka, GK; Hussl, S; Kosenburger, K; Schicker, K; Sitte, HH; Waldhoer, M; Yang, JW | 1 |
| Berg, RH; Govindarajulu, M; Kim, SY; Libault, M; Stacey, G; Tanaka, K; Taylor, CG | 1 |
| Barajas-Espinosa, AR; Chisholm, SP; deVries, M; Lomax, AE; Neshat, S; Skeith, L | 1 |
| Chen, B; Chowdhury, S; Guo, L; Nixon, BT; Sysoeva, TA | 1 |
| Bouïs, D; Broekman, MJ; Hyman, MC; Lawrence, DA; Liao, H; Marcus, AJ; Petrovic-Djergovic, D; Pinsky, DJ; Su, EJ; Visovatti, SH; Yanamadala, S | 1 |
| Bjelobaba, I; Lavrnja, I; Mostarica-Stojkovic, M; Nedeljkovic, N; Pekovic, S; Stojiljkovic, M; Stosic-Grujicic, S | 1 |
| Bagatini, M; Becker, L; Bellé, L; Correa, M; de Oliveira, L; Mazzanti, CM; Morsch, VM; Schetinger, MR; Schmatz, R; Spanevello, RM; Stefanello, N; Thomé, G | 1 |
| Chen, R; Das, NA; Gelman, AE; Jeong, SS; Kreisel, D; Krupnick, AS; Lai, J; Li, W; Lin, X; Okazaki, M; Patterson, GA; Sugimoto, S | 1 |
| Battastini, AM; Braganhol, E; Campesato, LF; Schetinger, MR; Wyse, AT; Zanin, RF | 1 |
| Bagatini, M; Bellé, LP; Correa, M; Mazzanti, CM; Moretto, MB; Morsch, VM; Oliveira, L; Rosa, C; Schetinger, MR; Schmatz, R; Spanevello, RM; Stefanello, N; Thomé, G | 1 |
| Banz, Y; Beldi, G; Candinas, D; Enjyoji, K; Graubardt, N; Junger, WG; Kroemer, A; Li, X; Nowak, M; Rellstab, A; Robson, SC; Sun, X; Wu, Y | 1 |
| Becker, LV; Corrêa, Mde C; Ethur, Jda S; Maldonado, PA; Morsch, VM; Negrini, LA; Oliveira, L; Schetinger, MR; Zanin, RF | 1 |
| Barbosa, GM; Battisti, V; Fleck, J; Leal, CA; Leal, DB; Morsch, VM; Pereira, RS; Santos, RC; Saucedo, EM; Schetinger, MR | 1 |
| Amisten, S; Erlinge, D; Lundquist, I; Meidute-Abaraviciene, S; Olde, B; Salehi, A; Tan, C | 1 |
| Conley, PB; Hanley, PJ; Isfort, K; Kim, HC; Kronlage, M; Leipziger, J; Robaye, B; Sargin, S; Schön, P; Schwab, A; Schwerdtle, T; Song, J; Sorokin, L | 1 |
| Aranda, G; Blizard, M; Canales, AA; Clark, G; Gomez, D; Herz, N; Nyberg, T; Ogoti, J; Onyirimba, J; Pham, T; Roux, SJ; Terry, A; Torres, J; Wat, N; Wu, J; Wu, M | 1 |
| Battastini, AM; Caumo, W; de Souza, A; Detanico, BC; Hidalgo, MP; Medeiros, LF; Rozisky, JR; Torres, IL | 1 |
| Lecka, J; Rana, MS; Sévigny, J | 1 |
| Knox, DP; Matthews, JB; Meikle, LI; Nisbet, AJ; Wildblood, LA; Zarlenga, DS | 1 |
| Battista, AG; Faillace, MP; Ricatti, MJ; Zorrilla Zubilete, M | 1 |
| Elima, K; Jalkanen, S; Karikoski, M; Laurila, JP; Marttila-Ichihara, F; Niemelä, J; Salmi, M; Yegutkin, GG | 1 |
| Bassler, N; Dezfouli, S; Hickey, MJ; Hohmann, JD; Jackson, S; Jia, F; Krajewski, S; Kurz, J; Nandurkar, H; Peter, K; Selan, C; Straub, A; Wendel, HP; Westein, E; Yuan, Y | 1 |
| Cervantes, A; Clark, G; Fraley, D; Kim, J; Liu, A; Onyirimba, J; Roux, SJ; Steinebrunner, I; Tang, W; Torres, J | 1 |
| Burns, N; Gerasimovskaya, EV; Helenius, M; Jalkanen, S; Kaczmarek, E; Stenmark, K; Yegutkin, GG | 1 |
| Brusa, D; Coscia, M; D'Arena, G; Deaglio, S; Gaidano, G; Horenstein, AL; Inghirami, G; Laurenti, L; Malavasi, F; Robson, SC; Rossi, D; Serra, S; Tripodo, C; Vaisitti, T | 1 |
| Berndt, M; Canney, A; Conlon, N; Crowley, D; Ducrée, J; Dunne, E; Egan, K; Ffrench, B; Finn, S; Gallagher, M; Keegan, H; Kenny, D; Laios, A; Martin, C; McEneaney, V; McEvoy, L; Norris, L; O'Leary, J; O'Toole, S; Sheils, O; Smith, L; Smyth, P; Spillane, C; Stordal, B | 1 |
| Krauss, M; Schäfer, P; Sträter, N; Zebisch, M | 1 |
| Jalkanen, S; Robson, SC; Wieringa, B; Yegutkin, GG | 1 |
| Bertoncheli, Cde M; Jaques, JA; Leal, CA; Leal, DB; Luz, SC; Pinheiro, Kde V; Rocha, BC; Ruchel, JB; Schetinger, MR; Souza, Vdo C; Stainki, DR; Zimmermann, CE | 1 |
| Balduini, A; Cattaneo, M; Currao, M; Di Buduo, CA; Jakubowski, JA; Lecchi, A; Malara, A; Pallotta, I; Rebuzzini, P | 1 |
| Kanjanamekanant, K; Luckprom, P; Pavasant, P | 1 |
| Wang, Y; Yang, C; Zhang, Y; Zong, H | 1 |
| Grković, I; Horvat, A; Ignjatović, M; Milošević, M; Petrović, S; Veličković, N | 1 |
| Becker, LV; Bertoldo, TM; de Vargas Pinheiro, K; Dos Santos Jaques, JA; Leal, CA; Leal, DB; Morsch, VM; Schetinger, MR; Souza, Vdo C | 1 |
| Chaikof, EL; Hagemeyer, CE; Haller, CA; Hohmann, JD; Krajewski, S; Nandurkar, HH; Peter, K; Selan, C; Straub, A; Wang, X | 1 |
| Brosseau, JP; Cadot, C; d'Orléans-Juste, P; Fausther, M; Fischer, B; Gillerman, I; Künzli, B; Lecka, J; Martín-Satué, M; Munkonda, MN; Poirier, D; Rousseau, E; Salem, M; Sévigny, J | 1 |
| Arakawa, T; Ito, M; Mizoguchi, I; Okayama, M; Shitara, A; Takuma, T | 1 |
| Bialkowska, K; Bledzka, KM; Dowling, JJ; Fox, PL; Hazen, SL; Ma, Y; Ma, YQ; Plow, EF; Pluskota, E; Podrez, EA; Soloviev, DA; Szpak, D | 1 |
| Krug, U; Sträter, N; Totzauer, R; Zebisch, M | 1 |
| Bigda, JJ; Gołuńska, M; Kolasa, J; Koszałka, P; Pryszlak, A; Składanowski, AC; Stasiłojć, G | 1 |
| Bhardwaj, R; Da'dara, AA; Skelly, PJ | 1 |
| Abendschein, D; Broekman, MJ; Chen, R; Drosopoulos, JH; Jeong, SS; Marcus, AJ; Moeckel, D; Nguyen, A; Robson, SC; Sun, X | 1 |
| Csizmadia, E; Enjyoji, K; Feldbrügge, L; Jiang, ZG; McKnight, CJ; Moss, A; Müller, CE; Robson, SC; Stephan, H; Tigges, J; Toxavidis, V; Wu, Y | 1 |
| Flaumenhaft, R; Furie, B; Furie, BC; Gopal, S; Jasuja, R; Kim, SH; Sharda, A | 1 |
| Aalto, K; Hakovirta, H; Hollmén, M; Jalkanen, J; Jalkanen, S; Kiviniemi, T; Salomaa, V; Yegutkin, GG | 1 |
| Cristóvão, G; Cunha, RA; George, J; Gomes, CA; Gonçalves, FQ; Gonçalves, T; Meyer Fernandes, JR; Rodrigues, L | 1 |
| Baek, AE; Goonewardena, SN; Hyman, MC; Jo, H; Kanthi, Y; Liao, H; Neral, MK; Pinsky, DJ; Sutton, NR; Visovatti, SH | 1 |
| Chen, X; Dai, J; Fan, X; Liu, J; Lu, Y; Wang, C; Wang, K; Wu, X; Zhang, J | 1 |
| Chiu, TY; Heazlewood, JL; Lao, J; Loqué, D; Manalansan, B; Roux, SJ | 1 |
| Cicko, S; Elze, M; Haager, B; Hoßfeld, M; Idzko, M; Korcan Ayata, C; Kübler, M; Lazar, Z; Meyer, A; Passlick, B; Schmid, S; Wiesemann, S; Zissel, G | 1 |
| Adefegha, SA; Becker, LV; Castilhos, LG; Doleski, PH; Leal, DB; Ruchel, JB | 1 |
| Chepurko, E; Covarrubias, R; Cowan, PJ; Dwyer, KM; Gumina, RJ; Huttinger, R; Huttinger, ZM; Novitskaya, T; Reynolds, A; Robson, SC; Stanfill, K; Wheeler, DG | 1 |
| Caiazzo, E; Cicala, C; Ialenti, A; Russo, GL; Spagnuolo, C; Tedesco, I | 1 |
| Eichelberger, B; Fedrizzi, S; Gremmel, T; Panzer, S; Weigel, G | 1 |
| Bottari, NB; Da Silva, AS; de Sá, MF; do Carmo, GM; Doleski, PH; Grando, TH; Gressler, LT; Henker, LC; Leal, DB; Mendes, RE; Monteiro, SG | 1 |
| Adefegha, SA; Cabral, FL; Doleski, PH; Leal, DB | 1 |
| Gamliel, A; Gomori, JM; Kakhlon, O; Katz-Brull, R; Lossos, A; Meiner, V; Nardi-Schreiber, A; Sapir, G; Sosna, J | 1 |
| Guo, B; Hu, F; Jiang, P; Lee, I; Li, Z; Pan, L; Wei, W; Xing, F; Xu, J; Yang, J; Zhang, X | 1 |
| Abdalla, FH; Baldissarelli, J; Bornemann, CP; Cardoso, AM; Casali, E; de Oliveira, JS; Morsch, VM; Pillat, MM; Polachini, CRN; Schetinger, MRC; Schmatz, R; Ulrich, H | 1 |
| Bonnefoy, N; Brosseau, C; Brouard, S; Chesneau, M; Danger, R; Degauque, N; Dejou, C; Dubois, F; Durand, E; Durand, M; Eliaou, JF; Giral, M; Guerif, P; Soulillou, JP | 1 |
| Gerasimovskaya, E; Helenius, M; Jacquemet, G; Jalkanen, S; Losenkova, K; Tallgren, C; Yegutkin, GG; Zuccarini, M | 1 |
| Da'dara, AA; deLaforcade, AM; El-Beshbishi, SN; Elzoheiry, M; Skelly, PJ | 1 |
| Huang, W; Li, Z; Tian, D; Wang, X; Wei, G; Zhang, Y | 1 |
| Clark, G; Roux, SJ | 1 |
| Fiore, M; Pillois, X; Pouget, T | 1 |
| Anyanwu, AC; Chi, L; Desch, KC; Fukase, K; Gruca, M; Hyman, MC; Kanthi, Y; Kaskar, S; Liao, H; Mimura, T; Pinsky, DJ; Sheikh-Aden, H; Wakefield, TW; Yadav, V; Zhao, R | 1 |
| Bauchrowitz, E; Benhidjeb, T; Duhme, C; Jurk, K; Kehrel, BE; Knoefel, WT; Kolokotronis, T; Krüger, M; Lehwald, N; Ngepi, A; Robson, SC; Schmelzle, M; Schulte Am Esch, J | 1 |
| Dziodzio, J; Eldridge, A; Emery, IF; Ichinose, F; Leclerc, A; Lord, C; Lucas, FL; May, T; McCrum, B; Riker, R; Robich, MP; Ryzhov, S; Sawyer, DB; Seder, DB | 1 |
| Goueli, SA; Hsiao, K | 1 |
| Battastini, AMO; Bertoni, APS; Braganhol, E; de Campos, RP; Stefani, GP; Tamajusuku, ASK; Wink, MR | 1 |
| Ávila-Ibarra, LR; Azucena Don-López, C; Chacón-Salinas, R; de Lourdes Mora-García, M; Del Carmen Aguilar-Lemarroy, A; García-Rocha, R; Hernández-Montes, J; Molina-Castillo, G; Monroy-García, A; Montesinos-Montesinos, JJ; Muñóz-Godínez, R; Pérez-Tapia, SM; Torres-Pineda, DB; Vallejo-Castillo, L; Weiss-Steider, B | 1 |
| Chun, BJ; Kekenes-Huskey, PM; Pace, T; Rahmaninejad, H | 1 |
| Alfaro, E; Cubillos-Zapata, C; Díaz-García, E; Galera, R; García-Rio, F; García-Tovar, S; López-Collazo, E; Mangas, A; Nanwani-Nanwani, K; Pérez-de-Diego, R; Rodríguez-Gallego, C; Ruíz-Hernández, JJ; Solé-Violán, J; Van-Den-Rym, A; Zamarrón, E | 1 |
| Cheng, XD; Li, YJ; Wang, JH; Wang, L; Yang, B; Yang, X; Yu, NW; Zhang, J; Zhang, Q; Zhang, X | 1 |
| Azambuja, JH; Begnini, K; Bertoni, APS; Braganhol, E; da Cruz, LLP; da Silveira, F; de Souza, PO; Gelsleichter, NE; Haas, CB; Hasko, G; Leite, RO; Mohr, KR; Prá, MD; Soares, MS; Spanevello, RM; Wink, MR | 1 |
| Chee, XW; Gunasinghe, KKJ; Harper, MT; Rahman, T; Vadlamani, VMK | 1 |
5 review(s) available for adenosine diphosphate and apyrase
| Article | Year |
|---|---|
Thrombosis and inflammation as multicellular processes: significance of cell-cell interactions.
Topics: Adenosine Diphosphate; Apyrase; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Eicosanoids; Endothelium, Vascular; HSP70 Heat-Shock Proteins; Humans; Inflammation; Nitric Oxide; Platelet Activation; Thrombosis | 1995 |
Heterologous cell-cell interactions: thromboregulation, cerebroprotection and cardioprotection by CD39 (NTPDase-1).
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Animals; Antigens, CD; Apyrase; Aspirin; Cell Communication; Endothelial Cells; Hemostasis; Humans; Thrombosis | 2003 |
Role of CD39 (NTPDase-1) in thromboregulation, cerebroprotection, and cardioprotection.
Topics: Adenosine Diphosphate; Animals; Antigens, CD; Apyrase; Aspirin; Blood Vessels; Cardiotonic Agents; Cells, Cultured; Cerebral Infarction; Coronary Disease; Drug Evaluation, Preclinical; Endothelial Cells; Endothelium, Vascular; Fibrinolytic Agents; Humans; Mice; Mice, Knockout; Mutagenesis, Site-Directed; Neuroprotective Agents; Platelet Aggregation; Platelet Aggregation Inhibitors; Recombinant Proteins; Structure-Activity Relationship; Synaptosomes; Thrombosis | 2005 |
Role of Ca
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Apyrase; Calcium Signaling; NADPH Oxidases; Plant Proteins; Plants | 2018 |
Purinergic signaling: a potential therapeutic target for ischemic stroke.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Antigens, CD; Apyrase; Humans; Ischemic Stroke; Signal Transduction; Thrombosis | 2023 |
3 trial(s) available for adenosine diphosphate and apyrase
| Article | Year |
|---|---|
Adenosine 5'-diphosphate as a factor in platelet aggregation induced by human plasma remnant lipoproteins.
Topics: 2-Chloroadenosine; Adenosine Diphosphate; Adult; Animals; Apyrase; Chylomicrons; Cilostazol; Female; Guinea Pigs; Hematocrit; Humans; In Vitro Techniques; Lipoproteins, VLDL; Male; Mice; Mice, Inbred ICR; Microscopy, Electron, Scanning; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Rabbits; Rats; Rats, Wistar; Tetrazoles | 1998 |
Constitutively released adenosine diphosphate regulates proplatelet formation by human megakaryocytes.
Topics: Adenosine Diphosphate; Apyrase; Blood Platelets; Cells, Cultured; Female; Fetal Blood; Humans; Male; Megakaryocyte Progenitor Cells; Megakaryocytes; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12 | 2012 |
Post-thyroidectomy hypothyroidism increases the expression and activity of ectonucleotidases in platelets: Possible involvement of reactive oxygen species.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adult; Aged; Apyrase; Blood Platelets; Female; Gene Expression Regulation, Enzymologic; Humans; Hypothyroidism; Male; Middle Aged; Reactive Oxygen Species; Thyroidectomy | 2018 |
302 other study(ies) available for adenosine diphosphate and apyrase
| Article | Year |
|---|---|
Aggregation of platelets and inert particles induced by thrombin.
Topics: Adenosine Diphosphate; Apyrase; Fibrin Fibrinogen Degradation Products; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Microscopy, Electron; Microscopy, Phase-Contrast; Platelet Aggregation; Prostaglandins E; Sodium; Sulfites; Thrombin | 1976 |
A membrane-bound enzyme in rabbit aorta capable of inhibiting adenosine-diphosphate-induced platelet aggregation.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Aorta; Apyrase; Cell Extracts; Cell Membrane; Phosphoric Monoester Hydrolases; Platelet Aggregation; Rabbits; Thrombosis | 1977 |
Quantitative radioisotopic measurement and scanning electron microscopic study of platelet adherence to a collagen-coated surface and to subendothelium with a rotating probe device.
Topics: Adenosine Diphosphate; Animals; Aorta; Apyrase; Blood Platelets; Chromium Radioisotopes; Collagen; Edetic Acid; Endothelium; Hemoglobins; Platelet Adhesiveness; Platelet Aggregation; Rabbits | 1979 |
Effects of carrageenans on the aggregation of human blood platelets.
Topics: Adenosine Diphosphate; Apyrase; Aspirin; Blood Coagulation Tests; Carrageenan; Egtazic Acid; Humans; Male; Platelet Aggregation; Theophylline; Thrombin | 1979 |
Actin and myosin from blood platelets or muscle are potent aggregating agents.
Topics: Actins; Adenosine Diphosphate; Adenosine Triphosphatases; Animals; Apyrase; Blood Platelets; Calcium; Dialysis; Humans; Magnesium; Muscles; Myosins; Platelet Aggregation | 1976 |
Potentiation of ADP-ase activity of aortic rings by prostaglandin synthetase inhibitors and PGE1 [proceedings].
Topics: Adenosine Diphosphate; Animals; Aorta, Thoracic; Apyrase; Cyclooxygenase Inhibitors; Phosphoric Monoester Hydrolases; Prostaglandins E; Rabbits | 1977 |
Aggregation of gel-filtered guinea-pig platelets by lipoproteins.
Topics: Adenosine; Adenosine Diphosphate; Animals; Apyrase; Aspirin; Chromatography, Gel; Dipyridamole; Guinea Pigs; Lipoproteins; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Platelet Aggregation; Prostaglandins E | 1979 |
Effects of a sulphated xylan on aggregation of human blood platelets.
Topics: Adenosine Diphosphate; Apyrase; Bucladesine; Humans; Platelet Aggregation; Polysaccharides; Thrombin; Time Factors; Xylans | 1979 |
Collagen-induced platelet aggregation:--evidence against the essential role of platelet adenosine diphosphate.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Blood Platelets; Collagen; Humans; Platelet Aggregation; Serotonin; Sheep | 1979 |
Role of platelets in aspirin-sensitive bronchoconstriction in the guinea-pig; interactions with salicylic acid.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Arachidonic Acids; Aspirin; Blood Platelets; Bradykinin; Bronchi; Drug Synergism; Guinea Pigs; Platelet Aggregation; Salicylates | 1978 |
In vitro interaction between cultured cells and human blood platelets.
Topics: Adenosine Diphosphate; Apyrase; Blood Platelets; Cell Line; Cells, Cultured; Humans; Lymphoma; Platelet Aggregation | 1978 |
ADP-induced refractory state of platelets in vitro. II. Functional and ultra studies on gel filtered platelets.
Topics: Adenine; Adenosine Deaminase; Adenosine Diphosphate; Albumins; Apyrase; Blood Platelets; Calcium Chloride; Chromatography, Gel; Glucose; Platelet Aggregation; Sodium Chloride; Temperature | 1977 |
Rat platelet aggregation by ATP. Aggregometrical and ultrastructural comparison with aggregations induced by ADP and collagen.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Apyrase; Aspirin; Blood Platelets; Collagen; Female; Humans; Male; Platelet Aggregation; Rats | 1976 |
The possible role of palmitoyl-CoA in the regulation of the adenine nucleotides transport in mitochondria under different metabolic states. I. Comparison of liver mitochondria from starved and fed rats.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Biological Transport, Active; Coenzyme A; Kinetics; Membranes; Mitochondria, Liver; Palmitic Acids; Rats; Starvation | 1975 |
Dissociation of clot retraction from platelet granule fusion and degranulation: an ultrastructural study of Reptilase-human platelet-rich plasma clots.
Topics: Adenosine Diphosphate; Amitriptyline; Apyrase; Batroxobin; Blood Coagulation; Blood Platelets; Cytoplasmic Granules; Dipyridamole; Fibrin; Humans; Indomethacin; Papaverine; Peptide Hydrolases; Platelet Aggregation; Prostaglandins E; Time Factors | 1975 |
ADP, thrombin, and Bothrops atrox thrombinlike enzyme in platelet-dependent fibrin retraction.
Topics: Adenosine Diphosphate; Animals; Apyrase; Batroxobin; Blood Platelets; Clot Retraction; Collagen; Creatine Kinase; Epinephrine; Hirudins; Humans; Phosphocreatine; Snake Venoms; Snakes; Thrombin | 1975 |
Evidence for inhibition of platelet activation in blood by a drug effect on erythrocytes.
Topics: Adenosine Diphosphate; Apyrase; Chlorpromazine; Erythrocytes; Humans; Platelet Aggregation; Proadifen | 1976 |
Low concentrations of sodium azide specifically inhibit a thromboxane A2 pathway in human platelets.
Topics: Adenosine Diphosphate; Apyrase; Arachidonic Acid; Aspirin; Azides; Blood Platelets; Calcium; Collagen; Energy Metabolism; Enzyme Activation; Humans; Hydrogen-Ion Concentration; Myosin-Light-Chain Kinase; Platelet Activation; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Secretory Rate; Serotonin; Sodium Azide; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2 | 1992 |
Platelet activation and subsequent inhibition by plasmin and recombinant tissue-type plasminogen activator.
Topics: Adenosine Diphosphate; Apyrase; Aspirin; Blood Platelets; Calcimycin; Calcium; Fibrinolysin; Humans; Platelet Activation; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Recombinant Proteins; Serotonin; Streptokinase; Tissue Plasminogen Activator | 1992 |
Modulation of anti-Thy1 nephritis in the rat by adenine nucleotides. Evidence for an anti-inflammatory role for nucleotidases.
Topics: 2-Chloroadenosine; Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apyrase; Female; Glomerulonephritis; In Vitro Techniques; Isoantibodies; Neutrophils; Platelet Aggregation; Rats; Rats, Inbred Strains; Thionucleotides | 1992 |
Platelet activation by cross-linking HLA class I molecules and Fc receptor.
Topics: Adenosine Diphosphate; Antibodies, Monoclonal; Apyrase; Aspirin; Blood Platelets; Calcium; Cross-Linking Reagents; Cytoplasmic Granules; Histocompatibility Antigens Class I; Humans; Hydrogen-Ion Concentration; Immunoglobulin G; Inositol 1,4,5-Trisphosphate; Phosphoproteins; Platelet Activation; Platelet Aggregation; Receptors, Fc; Thromboxane A2 | 1992 |
Effects of undernutrition during suckling on ATP and ADP hydrolysis by synaptosomes from the cerebral cortex of adult rats.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Age Factors; Animals; Apyrase; Biomarkers; Body Weight; Brain; Cerebral Cortex; Hydrolysis; Organ Size; Protein-Energy Malnutrition; Rats; Synaptic Transmission; Synaptosomes | 1991 |
Saliva of the soft tick, Ornithodoros moubata, contains anti-platelet and apyrase activities.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Apyrase; Calcium; Cations, Divalent; Humans; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Magnesium; Platelet Aggregation Inhibitors; Saliva; Species Specificity; Ticks | 1991 |
Mechanism of ethanol-induced aggregation in whole blood.
Topics: Adenosine Diphosphate; Animals; Apyrase; Collagen; Ethanol; Female; Hemolysis; Humans; Iloprost; In Vitro Techniques; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Inbred Strains | 1991 |
ADP plays an important role in mediating platelet aggregation and cyclic flow variations in vivo in stenosed and endothelium-injured canine coronary arteries.
Topics: Adenosine Diphosphate; Animals; Apyrase; Bridged Bicyclo Compounds, Heterocyclic; Clopidogrel; Coronary Circulation; Coronary Disease; Coronary Vessels; Dogs; Endothelium, Vascular; Fatty Acids, Unsaturated; Female; Hydrazines; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Serotonin; Thromboxane A2; Ticlopidine | 1992 |
The inhibition of platelet aggregation of metastatic H-ras-transformed 10T1/2 fibroblasts with castanospermine, an N-linked glycoprotein processing inhibitor.
Topics: Adenosine Diphosphate; Animals; Apyrase; Cell Line; Cell Transformation, Neoplastic; Fibroblasts; Genes, ras; Glucosidases; Glycoproteins; Hirudins; Humans; In Vitro Techniques; Indolizines; Kinetics; Mice; Platelet Aggregation; Platelet Aggregation Inhibitors; Transfection | 1991 |
Characterization of an ATP diphosphohydrolase (EC 3.6.1.5) in synaptosomes from cerebral cortex of adult rats.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Apyrase; Cerebral Cortex; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Male; Rats; Rats, Inbred Strains; Substrate Specificity; Synaptosomes | 1991 |
Platelet activation by a synthetic hydrophobic polymer, polymethylmethacrylate.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Apyrase; Aspirin; Blood Platelets; Calcium; Chymotrypsin; Fibrinogen; Humans; Methylmethacrylates; Microscopy, Electron; Microscopy, Electron, Scanning; Microspheres; Molecular Sequence Data; Phosphorylation; Platelet Activation; Platelet Aggregation; Protein Kinase C; Serotonin | 1991 |
Inhibition of platelet function by an aspirin-insensitive endothelial cell ADPase. Thromboregulation by endothelial cells.
Topics: Adenosine Diphosphate; Apyrase; Aspirin; Blood Platelets; Endothelium, Vascular; Humans; In Vitro Techniques; Nitric Oxide; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombin | 1991 |
Demonstration of antithrombotic activity of glomerular adenosine diphosphatase.
Topics: Adenosine Diphosphate; Animals; Apyrase; Female; Fibrinolytic Agents; Guanosine Diphosphate; Histocytochemistry; Inosine Triphosphate; Kidney Glomerulus; Platelet Aggregation; Rats; Uridine Diphosphate | 1991 |
An ADPase-like substance in placental extracts.
Topics: Adenosine Diphosphate; Alkaline Phosphatase; Apyrase; Blood Proteins; Chromatography; Electrophoresis, Polyacrylamide Gel; Humans; In Vitro Techniques; Leucyl Aminopeptidase; Muramidase; Placental Extracts; Platelet Aggregation; Platelet Aggregation Inhibitors; Urokinase-Type Plasminogen Activator | 1990 |
Endothelium-dependent vasorelaxations in response to aggregating platelets are impaired in reversed vein grafts.
Topics: Adenosine Diphosphate; Animals; Apyrase; Calcimycin; Carotid Arteries; Endothelium, Vascular; Indomethacin; Jugular Veins; Male; Methiothepin; Nitric Oxide; Platelet Aggregation; Rabbits; Serotonin | 1990 |
Remarkable activities of nucleoside triphosphate hydrolase in the tachyzoites of both virulent and avirulent strains of Toxoplasma gondii.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Apyrase; Dithiothreitol; Female; Kinetics; Mice; Rats; Toxoplasma; Toxoplasmosis, Animal; Virulence | 1990 |
Undernutrition during the preweaning period changes calcium ATPase and ADPase activities of synaptosomal fractions of weanling rats.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Animals, Suckling; Apyrase; Body Weight; Brain; Calcium-Transporting ATPases; Hydrolysis; Nutrition Disorders; Organ Size; Phosphoric Monoester Hydrolases; Rats; Rats, Inbred Strains; Synaptosomes; Weaning | 1990 |
[The maintenance of placental circulation--the study on the platelet inhibition activity of placental chorioepithelial brush border membrane].
Topics: Adenosine Diphosphate; Apyrase; Arachidonic Acids; Female; Humans; Microvilli; Placenta; Platelet Aggregation Inhibitors; Pregnancy; Ristocetin; Thromboxane A2; Trophoblasts | 1990 |
The kinetics of inhibition of alpha-thrombin in human plasma.
Topics: Adenosine Diphosphate; alpha-Macroglobulins; Amino Acid Chloromethyl Ketones; Aprotinin; Apyrase; Blood; Blood Platelets; Calcium; Factor VIII; Fibrin; Humans; Kinetics; Phosphatidylcholines; Phosphatidylserines; Thrombin | 1986 |
Ca-dependent ADPase--the possible regulator of calcium channel during the deficiency of ATP.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Azides; Calcium; Calcium-Transporting ATPases; In Vitro Techniques; Ion Channels; Kinetics; Male; Myocardium; Phosphoric Monoester Hydrolases; Rats; Rats, Inbred Strains; Sarcolemma; Sodium Azide | 1987 |
Platelet activation induced by a stable analogue of endoperoxides (U46619)
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Apyrase; beta-Thromboglobulin; Blood Platelets; Fibrinogen; Humans; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic | 1989 |
Metabolism of adenine nucleotides in human blood.
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Apyrase; Cells, Cultured; Dipyridamole; Endothelium, Vascular; Humans; Hydrolysis; Kinetics; Nucleotidases; Plasma | 1989 |
[The study on the platelet aggregation inhibition activity of placental brush border (the mechanism of platelet aggregation inhibition)].
Topics: Adenosine Diphosphate; Apyrase; Arachidonic Acids; Blood Platelets; Collagen; Female; Humans; Malondialdehyde; Microvilli; Placenta; Platelet Aggregation; Platelet Aggregation Inhibitors; Pregnancy; Ristocetin | 1989 |
Mechanisms of platelet activation by cultured human cancer cells and cells freshly isolated from tumor tissues.
Topics: Adenosine Diphosphate; Adult; Apyrase; Blood Platelets; Breast Neoplasms; Cell Communication; Cell Separation; Colonic Neoplasms; Concanavalin A; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Hirudins; Humans; Melanoma; Platelet Aggregation; Tumor Cells, Cultured | 1989 |
Platelet inhibitory activity in placentas from normal and abnormal pregnancies.
Topics: Abruptio Placentae; Adenosine Diphosphate; Apyrase; Female; Fetal Growth Retardation; Humans; Phosphoric Monoester Hydrolases; Placenta; Placental Extracts; Platelet Aggregation; Pregnancy; Pregnancy Complications, Cardiovascular | 1987 |
Purification and partial characterization of adenosine diphosphatase activity in bovine aorta microsomes.
Topics: Adenosine Diphosphate; Animals; Aorta; Apyrase; Calcium; Cattle; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; Magnesium; Microsomes; Octoxynol; Phosphoric Monoester Hydrolases; Platelet Aggregation; Polyethylene Glycols; Substrate Specificity | 1987 |
Demonstration of a novel ecto-enzyme on human erythrocytes, capable of degrading ADP and of inhibiting ADP-induced platelet aggregation.
Topics: Adenosine Diphosphate; Apyrase; Erythrocyte Membrane; Erythrocytes; Humans; Kinetics; Phosphates; Phosphoric Monoester Hydrolases; Platelet Aggregation | 1988 |
Growth inhibition of transformed mouse fibroblasts by adenine nucleotides occurs via generation of extracellular adenosine.
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Apyrase; Biological Transport; Blood; Cell Division; Cell Line, Transformed; Dipyridamole; Fibroblasts; Mice; Nucleotidases; Thioinosine; Uridine Triphosphate | 1988 |
Blood-finding strategy of a capillary-feeding sandfly, Lutzomyia longipalpis.
Topics: Adenosine Diphosphate; Animals; Apyrase; Blood; Capillaries; Collagen; Diptera; Erythema; Female; Humans; Platelet Aggregation; Rabbits; Salivary Glands; Tissue Extracts | 1986 |
Phospholipase C from clostridium perfringens induces human platelet aggregation in plasma.
Topics: Adenosine Diphosphate; Adult; Apyrase; Arachidonic Acid; Arachidonic Acids; Aspirin; Clostridium perfringens; Female; Humans; In Vitro Techniques; Male; Platelet Aggregation; Type C Phospholipases | 1988 |
Evidence for the dependence of arterial haemostasis on ADP.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Animals; Apyrase; Hemorrhage; Hemostasis; Male; Mesenteric Arteries; Mesenteric Veins; Mice; Phosphoric Monoester Hydrolases; Rats; Rats, Inbred Strains; Receptors, Purinergic; Reference Values | 1988 |
Thromboxane- and ADP-independent aggregation and exposure of fibrinogen receptors on platelets from patients with familial hypercholesterolemia.
Topics: Adenosine Diphosphate; Adolescent; Adult; Apyrase; Aspirin; Child; Female; Humans; Hyperlipoproteinemia Type II; Male; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Thromboxanes | 1985 |
A new murine monoclonal antibody reports an activation-dependent change in the conformation and/or microenvironment of the platelet glycoprotein IIb/IIIa complex.
Topics: Adenosine Diphosphate; Alprostadil; Antibodies, Monoclonal; Antibody Specificity; Apyrase; Blood Platelets; Calcimycin; Dibucaine; Epinephrine; Glycoproteins; Humans; Kinetics; Macromolecular Substances; Membrane Proteins; Platelet Aggregation; Platelet Membrane Glycoproteins; Prostaglandins E; Protein Conformation; Receptors, Cell Surface; Thrombin | 1985 |
An ADPase from sarcoplasmic reticulum of rabbit muscle cleaves ADP bound to F-actin.
Topics: Actins; Adenosine Diphosphate; Animals; Apyrase; Kinetics; Muscles; Phosphoric Monoester Hydrolases; Rabbits; Sarcoplasmic Reticulum; Substrate Specificity | 1986 |
Demonstration of plasma-membrane adenosine diphosphatase activity in rat lung.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenylyl Cyclases; Adenylyl Imidodiphosphate; Alkaline Phosphatase; Animals; Apyrase; Cell Membrane; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Lung; Phosphoric Monoester Hydrolases; Rats | 1986 |
Salivary apyrase of Rhodnius prolixus. Kinetics and purification.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylate Kinase; Animals; Apyrase; Chromatography, Gel; Kinetics; Phosphoric Monoester Hydrolases; Rhodnius; Saliva; Substrate Specificity; Triatominae | 1986 |
Antithrombotic activity of glomerular adenosine diphosphatase in the glomerular basement membrane of the rat kidney.
Topics: Adenosine Diphosphate; Animals; Apyrase; Basement Membrane; Histocytochemistry; Kidney Glomerulus; Microscopy, Electron; Phosphoric Monoester Hydrolases; Platelet Aggregation; Rats; Thrombosis | 1987 |
Human platelet-tumor cell interactions vary with the tumor cell lines.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Alprostadil; Apyrase; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Breast Neoplasms; Carcinoma; Cell Line; Creatine Kinase; Humans; Neoplasm Metastasis; Platelet Aggregation; Thromboxane B2 | 1986 |
Plasma-dependent and -independent mechanisms of platelet aggregation induced by human tumour cell lines.
Topics: Adenosine Diphosphate; Adult; Apyrase; Blood Coagulation Tests; Calcium; Cell Communication; Cell Line; Colonic Neoplasms; Heparin; Hirudins; Humans; Plasma; Platelet Aggregation; Thrombin | 1987 |
Collagen increases cytoplasmic free calcium in human platelets.
Topics: Adenosine Diphosphate; Aminoquinolines; Apyrase; Aspirin; Blood Platelets; Calcium; Collagen; Cytoplasm; Fluorescent Dyes; Humans; Kinetics; Platelet Aggregation | 1986 |
Direct evidence for ATP modulation of sugar transport in human erythrocyte ghosts.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Apyrase; Biological Transport; Blood Glucose; Calcium; Cytochalasin B; Erythrocyte Membrane; Humans; Kinetics; Magnesium | 1986 |
Mechanism of human platelet activation by endotoxic glycolipid-bearing mutant Re595 of Salmonella minnesota.
Topics: Adenosine Diphosphate; Apyrase; Bacterial Toxins; Blood Platelets; Cations, Divalent; Endotoxins; Fibrinogen; Glycolipids; Humans; Lipid A; Lipopolysaccharides; Mutation; Oligosaccharides; Phosphoproteins; Phosphorylation; Platelet Aggregation; Prostaglandins; Salmonella; Serotonin; Structure-Activity Relationship | 1986 |
Platelet aggregating activity mediated by thrombin generation in the NCG human neuroblastoma cell line.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Apyrase; Blood Coagulation; Calcium; Cell Line; Heparin; Humans; Neoplasm Metastasis; Neuraminidase; Neuroblastoma; Platelet Aggregation; Thrombin; Ultracentrifugation | 1987 |
Comparison of the interactions of fibrinogen and soluble fibrin with washed rabbit platelets stimulated with ADP.
Topics: Adenosine Diphosphate; Alprostadil; Animals; Apyrase; Blood Platelets; Creatine Kinase; Edetic Acid; Fibrin; Fibrinogen; Oligopeptides; Phosphocreatine; Platelet Aggregation; Prostaglandins E; Rabbits | 1985 |
Platelet aggregation in whole blood: the role of thromboxane A2 and adenosine diphosphate.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adenosine Diphosphate; Apyrase; Arachidonic Acid; Arachidonic Acids; Aspirin; Collagen; Cyclooxygenase Inhibitors; Epinephrine; Flurbiprofen; Humans; Imidazoles; In Vitro Techniques; Lipoxygenase Inhibitors; Platelet Aggregation; Pyrazoles; Thrombin; Thromboxane A2; Thromboxane-A Synthase | 1985 |
Subcellular localization and properties of rat liver adenosine diphosphatase.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Animals; Apyrase; In Vitro Techniques; Liver; Mitochondria, Liver; Phosphoric Monoester Hydrolases; Phosphorus Radioisotopes; Rats; Subcellular Fractions; Submitochondrial Particles | 1980 |
The anatomical distribution of ADPase activity in the rabbit aorta.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Aorta, Abdominal; Aorta, Thoracic; Apyrase; Inosine; Male; Phosphoric Monoester Hydrolases; Rabbits | 1982 |
The common occurrence of ATP diphosphohydrolase in mammalian plasma membranes.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Apyrase; Carcinoma, Small Cell; Cell Membrane; Humans; Hydrolysis; Phosphoric Monoester Hydrolases; Tissue Distribution | 1983 |
Comparison of effects of inhibitors on adenosine triphosphatase and adenosine diphosphatase activities in rat-liver mitochondria.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Apyrase; Atractyloside; Female; In Vitro Techniques; Intracellular Membranes; Mitochondria, Liver; Oligomycins; Phosphoric Monoester Hydrolases; Rats; Rats, Inbred Strains; Thionucleotides | 1984 |
[Antithrombogenic activity of vessel walls: the role of vascular ADPase].
Topics: Adenosine Diphosphate; Apyrase; Blood Vessels; Cell Wall; Humans; Phosphoric Monoester Hydrolases; Platelet Aggregation | 1983 |
Adrenaline and adenosine diphosphate-induced platelet aggregation require shape change. Importance of pseudopods.
Topics: Adenosine Diphosphate; Adolescent; Adult; Apyrase; Blood Platelets; Epinephrine; Female; Humans; In Vitro Techniques; Male; Microscopy, Phase-Contrast; Platelet Aggregation; Pseudopodia; Time Factors | 1984 |
The role of ADP secretion and thromboxane synthesis in factor VIII binding to platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Apyrase; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Collagen; Factor VIII; Humans; Prostaglandin Endoperoxides, Synthetic; Thrombin; Thromboxane A2; Thromboxanes | 1983 |
von Willebrand factor binds to platelets and induces aggregation in platelet-type but not type IIB von Willebrand disease.
Topics: Adenosine Diphosphate; Apyrase; Blood Coagulation Factors; Blood Platelets; Factor VIII; Female; Fibrinogen; Humans; Male; Platelet Aggregation; Thrombin; von Willebrand Diseases; von Willebrand Factor | 1983 |
Activation of human platelet phospholipase C by ionophore A23187 is totally dependent upon cyclo-oxygenase products and ADP.
Topics: Adenosine Diphosphate; Apyrase; Aspirin; Blood Platelets; Calcimycin; Enzyme Activation; Humans; In Vitro Techniques; Lipids; Phospholipases; Prostaglandin-Endoperoxide Synthases; Type C Phospholipases | 1984 |
Effects of acetyl glyceryl ether phosphorylcholine on human platelet function in vitro.
Topics: Adenosine Diphosphate; Apyrase; beta-Thromboglobulin; Blood Platelets; Calcium; Creatine Kinase; Drug Synergism; Humans; Lysophosphatidylcholines; Phosphocreatine; Platelet Activating Factor; Platelet Aggregation; Platelet Factor 4; Serotonin; Thromboxane A2 | 1981 |
Zymosan-induced chemiluminescence of granulocytes in incubated human whole blood. The role of platelets.
Topics: Adenosine Diphosphate; Apyrase; Blood; Blood Platelets; Granulocytes; Humans; Luminescent Measurements; Luminol; Zymosan | 1983 |
Interaction of normal, thrombasthenic, and Bernard-Soulier platelets with immobilized fibrinogen: defective platelet-fibrinogen interaction in thrombasthenia.
Topics: Acrylonitrile; Adenosine Diphosphate; Agglutination; Albumins; Apyrase; Blood Platelet Disorders; Blood Platelets; Cell Communication; Edetic Acid; Epinephrine; Fibrinogen; Humans; Immune Sera; Platelet Adhesiveness; Platelet Aggregation; Platelet Count; Thrombin | 1980 |
Correlation between fibrinogen binding to human platelets and platelet aggregability.
Topics: Adenosine Diphosphate; Apyrase; Binding Sites; Blood Platelet Disorders; Blood Platelets; Edetic Acid; Fibrinogen; Humans; Platelet Aggregation; Temperature | 1980 |
An investigation into the role of coagulation factor XIII in ADP-induced aggregation and fibrinogen binding with rabbit platelets.
Topics: Adenosine Diphosphate; Animals; Antithrombin III; Apyrase; Creatine Kinase; Factor XIII; Fibrinogen; Heparin; Humans; Phosphocreatine; Platelet Aggregation; Protein Binding; Rabbits | 1982 |
Synergistic responses and receptor occupancy in rabbit blood platelets.
Topics: Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Animals; Apyrase; Blood Platelets; Clomipramine; Drug Synergism; Epinephrine; Platelet Aggregation; Rabbits; Receptors, Adrenergic; Receptors, Serotonin; Serotonin; Yohimbine | 1982 |
Thrombin-induced formation of a polar lipid material within platelets that possesses platelet-activating activity.
Topics: Adenosine Diphosphate; Animals; Apyrase; Arachidonic Acids; Blood Platelets; Cattle; Indomethacin; Lipids; Lysophosphatidylcholines; Platelet Activating Factor; Platelet Aggregation; Rabbits; Thrombin | 1980 |
Differing platelet aggregating effects by two tumor cell lines: absence of role for platelet-derived ADP.
Topics: Adenosine Diphosphate; Animals; Apyrase; Blood Platelets; Cell Line; Cell Membrane; Glioma; Heparin; Hirudins; Humans; Membrane Proteins; Mice; Neoplasms, Experimental; Phospholipase D; Platelet Aggregation | 1981 |
Platelet adhesion onto sulfonated artificial red blood cells.
Topics: Adenosine Diphosphate; Animals; Apyrase; Blood Substitutes; Hemoglobins; Hemolysis; Kinetics; Nylons; Platelet Adhesiveness; Platelet Aggregation; Rabbits | 1981 |
Reversibility of the association of fibrinogen with rabbit platelets exposed to ADP.
Topics: Adenosine Diphosphate; Animals; Apyrase; Binding Sites; Blood Platelets; Fibrinogen; Humans; Iodine Radioisotopes; Platelet Aggregation; Rabbits | 1980 |
Relationship of ADP-induced fibrinogen binding to platelet shape change and aggregation elucidated by use of colchicine and cytochalasin B.
Topics: Adenosine Diphosphate; Apyrase; Blood Platelets; Colchicine; Cytochalasin B; Fibrinogen; Humans; Platelet Aggregation | 1980 |
Haemostatic platelet plug formation in the isolated rabbit mesenteric preparation--an analysis of red blood cell participation.
Topics: Acetaldehyde; Adenosine Diphosphate; Animals; Apyrase; Blood Platelets; Erythrocytes; Female; Hemostasis; Male; Mesenteric Arteries; Mesenteric Veins; Rabbits; Time Factors | 1980 |
Action of immobilized neuraminidase on the accumulation of 5-hydroxytryptamine by human platelets.
Topics: Adenosine Diphosphate; Apyrase; Blood Platelets; Chromatography, Gel; Clomipramine; Enzymes, Immobilized; Humans; Kinetics; Methysergide; Neuraminidase; Platelet Aggregation; Serotonin; Sialic Acids; Sialyltransferases | 1980 |
Salivary apyrase in New World blackflies (Diptera: Simuliidae) and its relationship to onchocerciasis vector status.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Calcium; Female; Humans; Hydrogen-Ion Concentration; Insect Vectors; Magnesium; Onchocerca volvulus; Onchocerciasis; Salivary Glands; Simuliidae; Substrate Specificity | 1995 |
Kinetics of relaxation from rigor of permeabilized fast-twitch skeletal fibers from the rabbit using a novel caged ATP and apyrase.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Biophysical Phenomena; Biophysics; In Vitro Techniques; Kinetics; Magnetic Resonance Spectroscopy; Models, Biological; Muscle Relaxation; Muscle, Skeletal; Myosins; Photolysis; Rabbits | 1994 |
Upregulation of antithrombotic ectonucleotidases by aspirin in human endothelial cells in-vitro.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Apyrase; Aspirin; Cells, Cultured; Chromatography, High Pressure Liquid; Endothelium, Vascular; Fluorescein-5-isothiocyanate; Humans; Spectrometry, Fluorescence; Umbilical Veins; Up-Regulation | 1994 |
Inhibition and kinetic alterations by excess free ATP and ADP of the ATP diphosphohydrolase activity (EC 3.6.1.5) from rat blood platelets.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Binding Sites; Blood Platelets; Calcium; Cations, Divalent; Enzyme Activation; Kinetics; Male; Rats; Rats, Wistar; Substrate Specificity | 1995 |
Transformed rat arterial smooth muscle cells induce platelet aggregation.
Topics: Adenosine Diphosphate; Animals; Apyrase; Blood Coagulation; Cell Line, Transformed; Edetic Acid; Hirudins; Iodoacetates; Iodoacetic Acid; Muscle, Smooth, Vascular; Phospholipase D; Phospholipases A; Phospholipases A2; Platelet Aggregation; Rats | 1994 |
Activation of skinned trabeculae of the guinea pig induced by laser photolysis of caged ATP.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Biophysical Phenomena; Biophysics; Calcium; Computer Simulation; Guinea Pigs; Heart; In Vitro Techniques; Kinetics; Lasers; Male; Myocardial Contraction; Myocardium; Photolysis | 1994 |
Inhibitory effect of cadmium acetate on synaptosomal ATP diphosphohydrolase (EC 3.6.1.5; apyrase) from adult rat cerebral cortex.
Topics: Acetates; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Apyrase; Cadmium; Cerebral Cortex; Hydrolysis; Kinetics; Male; Rats; Rats, Wistar; Substrate Specificity; Synaptosomes | 1994 |
Salivary apyrase in African and New World vectors of Plasmodium species and its relationship to malaria transmission.
Topics: Adenosine Diphosphate; Africa; Animals; Anopheles; Apyrase; Calcium; Female; Hydrogen-Ion Concentration; Insect Vectors; Magnesium; Malaria; Salivary Glands | 1994 |
Flash photolysis studies of relaxation and cross-bridge detachment: higher sensitivity of tonic than phasic smooth muscle to MgADP.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Bacterial Toxins; Guinea Pigs; Hemolysin Proteins; Isomerism; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Muscle, Smooth, Vascular; Myosins; Organophosphates; Phosphocreatine; Photolysis; Rabbits | 1993 |
Characterization of an ATP diphosphohydrolase activity (APYRASE, EC 3.6.1.5) in rat blood platelets.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Blood Platelets; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Male; Rats; Rats, Wistar; Substrate Specificity | 1993 |
Human placental ATP-diphosphohydrolase: biochemical characterization, regulation and function.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Apyrase; Binding, Competitive; Electrophoresis, Polyacrylamide Gel; Female; Humans; Hydrolysis; In Vitro Techniques; Kinetics; Lectins; Microsomes; Molecular Weight; Placenta; Platelet Aggregation; Pregnancy | 1994 |
Effects of L- and D-arginine and some related esters on the cytosolic mechanisms of alpha-thrombin-induced human platelet activation.
Topics: Adenosine Diphosphate; Apyrase; Arachidonic Acids; Arginine; Blood Platelets; Cyclic GMP; Cytosol; Humans; In Vitro Techniques; Indomethacin; Kinetics; Nitroprusside; Platelet Activation; Platelet Aggregation Inhibitors; Sodium-Hydrogen Exchangers; Spectrometry, Fluorescence; Stereoisomerism; Thrombin | 1993 |
Coordinated inhibition of actin-induced platelet aggregation by plasma gelsolin and vitamin D-binding protein.
Topics: Actins; Adenosine; Adenosine Diphosphate; Animals; Apyrase; Aspirin; Dose-Response Relationship, Drug; Gelsolin; Humans; Kinetics; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Vitamin D-Binding Protein | 1993 |
Reproductive condition, glomerular adenosine diphosphatase activity, and platelet aggregation in the rat: effect of endotoxin.
Topics: Adenosine Diphosphate; Animals; Apyrase; Endotoxins; Female; Kidney Glomerulus; Ovariectomy; Perfusion; Platelet Aggregation; Pregnancy; Pseudopregnancy; Rats; Rats, Wistar; Reproduction | 1993 |
Salivary gland extracts from the deerfly contain a potent inhibitor of platelet aggregation.
Topics: Adenosine Diphosphate; Animals; Apyrase; Blood Platelets; Cell Separation; Cyclic AMP; Cyclic GMP; Diptera; Electrophoresis, Polyacrylamide Gel; Fibrinogen; Humans; Kinetics; Molecular Weight; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Salivary Glands; Salivary Proteins and Peptides; Tissue Extracts | 1993 |
Roles of phospholipase C and Ca(2+)-ATPase in calcium responses of single, fibrinogen-bound platelets.
Topics: Adenosine Diphosphate; Apyrase; Aspirin; Blood Platelets; Calcium; Calcium-Transporting ATPases; Cytosol; Egtazic Acid; Fibrinogen; Fura-2; Humans; Inositol Phosphates; Kinetics; Platelet Activation; Spectrometry, Fluorescence; Terpenes; Thapsigargin; Thrombin; Type C Phospholipases; Video Recording | 1993 |
Characterization and localization of an ATP-diphosphohydrolase on the external surface of the tegument of Schistosoma mansoni.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Blood Platelets; Cricetinae; Histocytochemistry; Humans; Mesocricetus; Microscopy, Electron; Platelet Activation; Schistosoma mansoni; Schistosomiasis mansoni; Substrate Specificity | 1993 |
Platelet aggregation induced by the endoperoxide analogue U46619 is inhibited by polymorphonuclear leukocyte ADPase activity.
Topics: Adenosine Diphosphate; Apyrase; Blood Platelets; Chromatography, High Pressure Liquid; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic | 1993 |
Protein kinase C regulates tyrosine phosphorylation of pp125FAK in platelets adherent to fibrinogen.
Topics: Adenosine Diphosphate; Apyrase; Blood Platelets; Calcium; Cell Adhesion Molecules; Cell Size; Egtazic Acid; Enzyme Inhibitors; Fibrinogen; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Indoles; Maleimides; Phosphoproteins; Phosphorylation; Platelet Adhesiveness; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Kinase C; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Signal Transduction; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Tyrosine | 1996 |
Activation of receptor-operated cation channels via P2X1 not P2T purinoceptors in human platelets.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Apyrase; Aspirin; Blood Platelets; Calcium; Calcium Channels; Fluorescent Dyes; Fura-2; Humans; In Vitro Techniques; Membrane Potentials; Membrane Proteins; Patch-Clamp Techniques; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2Y12 | 1996 |
Hydrolysis of P2-purinoceptor agonists by a purified ectonucleotidase from the bovine aorta, the ATP-diphosphohydrolase.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Aorta; Apyrase; Binding, Competitive; Cattle; Cell Membrane; Hydrolysis; Kinetics; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2 | 1996 |
Apyrase activity and adenosine diphosphate induced platelet aggregation inhibition by the salivary gland proteins of Culicoides variipennis, the North American vector of bluetongue viruses.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Animals; Apyrase; Bluetongue; Bluetongue virus; Ceratopogonidae; Female; Insect Vectors; Kinetics; North America; Platelet Aggregation; Platelet Aggregation Inhibitors; Salivary Glands; Salivary Proteins and Peptides | 1996 |
Enzyme kinetics and the activation energy of Mg-ATPase in cardiac sarcolemma: ADP as an alternative substrate.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Azides; Ca(2+) Mg(2+)-ATPase; Enzyme Activation; Kinetics; Male; Myocardium; Rats; Rats, Wistar; Sarcolemma; Sodium Azide; Substrate Specificity; Thermodynamics | 1995 |
An in vitro method for evaluating vascular endothelial ADPase activity.
Topics: Adenosine Diphosphate; Animals; Apyrase; Azides; Calcium Chloride; Cattle; Chemistry Techniques, Analytical; Endothelium, Vascular; Enzyme Inhibitors; Sensitivity and Specificity; Sodium Azide; Xenobiotics | 1996 |
Kinetics of extracellular ATP hydrolysis by microvascular endothelial cells from rat heart.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Apyrase; Cells, Cultured; Dipyridamole; Endothelium, Vascular; Enzyme Inhibitors; Female; Hydrolysis; Kinetics; Microcirculation; Nucleotidases; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 1995 |
Loss of rat glomerular ATP diphosphohydrolase activity during reperfusion injury is associated with oxidative stress reactions.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antioxidants; Apyrase; Complement Activation; Endothelium, Vascular; Ischemia; Kidney; Kidney Glomerulus; Male; Oxidative Stress; Platelet Aggregation; Pregnatrienes; Rats; Rats, Inbred Lew; Reactive Oxygen Species; Reperfusion Injury | 1996 |
The role of ADP in endotoxin-induced equine platelet activation.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Apyrase; Blood Platelets; Endotoxins; Female; Horses; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Spectrophotometry | 1996 |
Apyrase administration prolongs discordant xenograft survival.
Topics: Adenosine Diphosphate; Animals; Aorta; Apyrase; Endothelium, Vascular; Graft Survival; Guinea Pigs; Heart Transplantation; Injections, Intra-Arterial; Male; Platelet Aggregation; Rats; Rats, Inbred Lew; Transplantation, Heterologous | 1996 |
Loss of ATP diphosphohydrolase activity with endothelial cell activation.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Sequence; Animals; Antibodies; Aorta; Apyrase; Cells, Cultured; Endothelium, Vascular; Humans; Hydrogen Peroxide; Inflammation; Kinetics; Molecular Sequence Data; Oxidative Stress; Peptide Fragments; Platelet Aggregation; Reperfusion Injury; Swine; Thionucleotides; Tumor Necrosis Factor-alpha | 1997 |
ADP-mimicking platelet aggregation caused by rugosin E, an ellagitannin isolated from Rosa rugosa Thunb.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Animals; Apyrase; Blood Platelets; Calcium; Creatine Kinase; Humans; Hydrolyzable Tannins; Inositol Phosphates; Phosphocreatine; Plant Extracts; Plants, Medicinal; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Tannins; Thromboxane B2 | 1997 |
Extracellular adenosine 5' triphosphate involvement in the death of LAK-engaged human tumor cells via P2X-receptor activation.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Apyrase; Calcium Channel Blockers; Cell Death; Cell Line; Colonic Neoplasms; Cytotoxicity, Immunologic; Humans; Killer Cells, Lymphokine-Activated; Receptors, Purinergic P2; Tetradecanoylphorbol Acetate; Thionucleotides; Tumor Cells, Cultured; Verapamil | 1997 |
Enhanced increases in cytosolic Ca2+ in ADP-stimulated platelets from patients with delta-storage pool deficiency--a possible indicator of interactions between granule-bound ADP and the membrane ADP receptor.
Topics: Adenosine Diphosphate; Apyrase; Aspirin; Blood Platelets; Blood Specimen Collection; Calcium; Cytoplasmic Granules; Cytosol; Humans; Platelet Storage Pool Deficiency; Receptors, Purinergic P2; Serotonin; Thrombin | 1997 |
Effects of 9-amino-1,2,3,4-tetrahydroacridine (THA) on ATP diphosphohydrolase (EC 3.6.1.5) and 5'-nucleotidase (EC 3.1.3.5) from rat brain synaptosomes.
Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Brain; Cerebral Cortex; Cholinesterase Inhibitors; Hippocampus; Hydrolysis; Kinetics; Male; Rats; Rats, Wistar; Synaptosomes; Tacrine | 1997 |
Mechanical study of rat soleus muscle using caged ATP and X-ray diffraction: high ADP affinity of slow cross-bridges.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Binding Sites; In Vitro Techniques; Male; Muscle Contraction; Muscle Fibers, Fast-Twitch; Muscle Fibers, Slow-Twitch; Muscle, Skeletal; Photolysis; Rats; Rats, Wistar; X-Ray Diffraction | 1997 |
Hydrolysis of extracellular adenine nucleotides by equine epidydimal spermatozoa.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Apyrase; Epididymis; Horses; Hydrolysis; Kinetics; Male; Nucleotidases; Nucleotides; Spermatozoa; Time Factors | 1997 |
Stage-specific expression of P2Y receptors, ecto-apyrase, and ecto-5'-nucleotidase in myeloid leukocytes.
Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Antigens, CD; Apyrase; Bucladesine; Cell Differentiation; Cytosol; DNA Primers; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Leukemia; Leukocytes; Models, Biological; Polymerase Chain Reaction; Receptors, Purinergic P2; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Tumor Cells, Cultured; Uridine Triphosphate | 1997 |
The Ca2+-mobilizing potency of alpha-thrombin and thrombin-receptor-activating peptide on human platelets -- concentration and time effects of thrombin-induced Ca2+ signaling.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Apyrase; Aspirin; Blood Platelets; Calcium; Cytosol; Egtazic Acid; Humans; In Vitro Techniques; Kinetics; Peptide Fragments; Platelet Activation; Receptors, Thrombin; Signal Transduction; Thrombin; Time Factors | 1997 |
Apyrase, ascorbic acid and aprotinin ameliorate the storage lesion in pelleted platelet preparations.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aprotinin; Apyrase; Ascorbic Acid; Blood Platelets; Blood Preservation; Humans; Leukocyte Count; Platelet Activation; Platelet Aggregation; Platelet Count | 1997 |
8-Azido-nucleotides as substrates of Torpedo electric organ apyrase. effect of photoactivation on apyrase activity.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Animals; Apyrase; Azides; Calcium-Transporting ATPases; Cell Membrane; Electric Organ; Enzyme Activation; Enzyme Inhibitors; In Vitro Techniques; Nerve Tissue Proteins; Photic Stimulation; Photochemistry; Torpedo | 1997 |
Divalent cation dependence and inhibition of Schistosoma mansoni ATP diphosphohydrolase by fluorosulfonylbenzoyl adenosine.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Cations; Enzyme Activation; Enzyme Inhibitors; Hydrolysis; Magnesium; Models, Molecular; Schistosoma mansoni | 1998 |
Inhibition of platelet function by recombinant soluble ecto-ADPase/CD39.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Blood Platelets; CHO Cells; Chromatography, Affinity; COS Cells; Cricetinae; Fibrinolytic Agents; Half-Life; Humans; Mice; Mice, Inbred BALB C; Recombinant Proteins; Solubility; Thromboembolism | 1998 |
The pharmacology and kinetics of ecto-nucleotidases in the perilymphatic compartment of the guinea-pig cochlea.
Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Antigens, CD; Antimetabolites; Apyrase; Ca(2+) Mg(2+)-ATPase; Cell Survival; Chromatography, High Pressure Liquid; Cochlea; Enzyme Inhibitors; Female; Guinea Pigs; Hydrolysis; In Vitro Techniques; Kinetics; L-Lactate Dehydrogenase; Male; Perilymph | 1998 |
Apyrase activity and platelet aggregation inhibitors in the tick Ornithodoros savignyi (Acari: Argasidae).
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Calcium; Chelating Agents; Dithiothreitol; Enzyme Inhibitors; Female; Hot Temperature; Humans; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Magnesium; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Protein Denaturation; Proteins; Salivary Glands; Substrate Specificity; Ticks | 1998 |
Difference of (Ca2+)i movements in platelets stimulated by thrombin and TRAP: the involvement of alpha(IIb)beta3-mediated TXA2 synthesis.
Topics: Adenosine Diphosphate; Antibodies, Monoclonal; Apyrase; Aspirin; Blood Platelets; Calcium; Cyclooxygenase Inhibitors; Dipeptides; Fibrinogen; Humans; Ion Transport; Peptide Fragments; Phenylacetates; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIb-IX Complex; Platelet Glycoprotein GPIIb-IIIa Complex; Receptors, Thrombin; Signal Transduction; Sulfonamides; Thrombin; Thromboxane A2; Thromboxane B2; Tirofiban; Tyrosine | 1998 |
Characterization of fetal serum 5'-nucleotide phosphodiesterase: a novel function as a platelet aggregation inhibitor in fetal circulation.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Apyrase; Binding, Competitive; Fetal Blood; Humans; Infant, Newborn; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Platelet Aggregation Inhibitors | 1998 |
Heparin modulates adenine nucleotide hydrolysis by synaptosomes from cerebral cortex.
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Apyrase; Calcium; Cerebral Cortex; Dextran Sulfate; Enzyme Inhibitors; Heparin; Hydrolysis; Magnesium; Potassium Chloride; Rats; Rats, Wistar; Synaptosomes | 1998 |
Secreted ADP plays a central role in thrombin-induced phospholipase D activation in human platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adenosine Triphosphate; Apyrase; Blood Platelets; Blood Proteins; Enzyme Activation; Fibrinogen; Humans; Phospholipase D; Phosphoproteins; Phosphorylation; Protein Processing, Post-Translational; Purinergic Antagonists; Receptors, Thromboxane; Signal Transduction; Thionucleotides; Thrombin | 1998 |
Secreted dense granule adenine nucleotides promote calcium influx and the maintenance of elevated cytosolic calcium levels in stimulated human platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Apyrase; Blood Platelets; Calcium; Cytoplasmic Granules; Cytosol; Drug Interactions; Fura-2; Humans; Ion Transport; Platelet Activation; Platelet Storage Pool Deficiency; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2X; Thrombin | 1999 |
Specific inhibition of ADP-induced platelet aggregation by clopidogrel in vitro.
Topics: Adenosine Diphosphate; Alprostadil; Apyrase; Blood Platelets; Clopidogrel; Cyclic AMP; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Serum Albumin; Stereoisomerism; Ticlopidine; Time Factors | 1999 |
Inhibition of an ecto-ATP-diphosphohydrolase by azide.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Azides; Chickens; Diphosphates; Enzyme Inhibitors; Fluorides; Hydrogen-Ion Concentration; Hydrolysis; Oviducts; Vanadates | 1999 |
Most apyrase preparations are impure and contain inhibitors of cathepsin G: suggestions for use of apyrase in preparation and stabilization of platelet suspensions.
Topics: Adenosine Diphosphate; Apyrase; Blood Platelets; Cathepsin G; Cathepsins; Humans; Plateletpheresis; Serine Endopeptidases | 1999 |
Platelet-released ADP stabilizes PAF-induced rabbit platelet aggregation by stabilizing intracellular calcium.
Topics: Adenosine Diphosphate; Animals; Apyrase; Blood Platelets; Calcium; Platelet Activating Factor; Platelet Aggregation; Rabbits | 1998 |
CD39-L4 is a secreted human apyrase, specific for the hydrolysis of nucleoside diphosphates.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Animals; Antigens, CD; Apyrase; Base Sequence; Cations, Divalent; COS Cells; DNA Primers; Enzyme Activation; Humans; Hydrolysis; Substrate Specificity | 1999 |
Nucleotides and cd39: principal modulatory players in hemostasis and thrombosis.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Blood Coagulation; Blood Flow Velocity; Hemostasis; Mice; Mice, Knockout; Platelet Activation; Signal Transduction; Thrombosis | 1999 |
Suppression of ATP diphosphohydrolase/CD39 in human vascular endothelial cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Antigens, CD; Apyrase; Base Sequence; Cell Line; Endothelium, Vascular; Enzyme Activation; Humans; Intracellular Fluid; Molecular Sequence Data; Oligonucleotides, Antisense; Protein Synthesis Inhibitors; RNA, Messenger; Transfection; Umbilical Veins | 1999 |
Analysis of CD39/ATP diphosphohydrolase (ATPDase) expression in endothelial cells, platelets and leukocytes.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Antigens, CD; Apyrase; Blood Platelets; Cells, Cultured; Endothelium, Vascular; Enzyme Induction; Glycosylation; Humans; Isoenzymes; Leukocytes; Megakaryocytes; Molecular Probe Techniques; Protein Processing, Post-Translational; Receptors, Purinergic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 1999 |
On the mechanism of plasmin-induced platelet aggregation. Implications of the dual role of granule ADP.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenylyl Cyclase Inhibitors; Apyrase; Blood Platelets; Calcium; Cell Degranulation; Drug Interactions; Epinephrine; Fibrinolysin; Fibrinolytic Agents; Humans; In Vitro Techniques; Ligands; Membrane Proteins; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y12 | 2000 |
Studies on ATP-diphosphohydrolase nucleotide-binding sites by intrinsic fluorescence.
Topics: Adenosine Diphosphate; Apyrase; Isoenzymes; Nucleotides; Plant Proteins; Solanum tuberosum; Spectrometry, Fluorescence | 2000 |
Immobilised echistatin promotes platelet adhesion and protein tyrosine phosphorylation.
Topics: Adenosine Diphosphate; Alprostadil; Apyrase; Blood Platelets; Cell Adhesion; Cytochalasin D; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Indoles; Integrins; Intercellular Signaling Peptides and Proteins; Maleimides; Peptides; Phosphorylation; Platelet Aggregation Inhibitors; Protein-Tyrosine Kinases; Tyrosine | 2000 |
New benzodiazepines alter acetylcholinesterase and ATPDase activities.
Topics: Acetylcholinesterase; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Benzodiazepines; Cerebral Cortex; Hydrolysis; Kinetics; Male; Rats; Rats, Wistar | 2000 |
Contribution of ecto-5'-nucleotidase to the inhibition of platelet aggregation by human endothelial cells.
Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Monophosphate; Apyrase; Blood Platelets; Cell Communication; Dinucleoside Phosphates; Endothelium, Vascular; Humans; Platelet Aggregation | 2000 |
ADP-induced platelet shape change: an investigation of the signalling pathways involved and their dependence on the method of platelet preparation.
Topics: Adenosine Diphosphate; Amides; Animals; Apyrase; Blood Platelets; Calcium; Calcium Signaling; Cell Size; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Humans; Intracellular Signaling Peptides and Proteins; Kinetics; Membrane Proteins; Mice; Platelet Activation; Protein Serine-Threonine Kinases; Pyridines; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; rho-Associated Kinases; Signal Transduction | 2000 |
CD39L2, a gene encoding a human nucleoside diphosphatase, predominantly expressed in the heart.
Topics: Acid Anhydride Hydrolases; Adenosine Diphosphate; Adenosine Triphosphatases; Adult; Animals; Antigens, CD; Apyrase; Calcium; Cations, Divalent; COS Cells; Cricetinae; Enzyme Activation; Humans; Hydrolysis; In Situ Hybridization; Kinetics; Myocardium; Protein Processing, Post-Translational; Recombinant Proteins; RNA, Messenger; Transfection | 2000 |
Walker A lysine mutations of TAP1 and TAP2 interfere with peptide translocation but not peptide binding.
Topics: Adenosine Diphosphate; Amino Acid Motifs; Animals; Apyrase; ATP Binding Cassette Transporter, Subfamily B, Member 3; ATP-Binding Cassette Transporters; Cell Line; DNA, Complementary; Dose-Response Relationship, Drug; Hydrolysis; Insecta; Kinetics; Lysine; Microsomes; Mutagenesis, Site-Directed; Mutation; Peptides; Precipitin Tests; Protein Binding; Protein Transport; Spectrometry, Fluorescence; Temperature; Time Factors | 2001 |
Endotoxin activation of macrophages does not induce ATP release and autocrine stimulation of P2 nucleotide receptors.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Apyrase; Autocrine Communication; Cell Line; Endotoxins; Enzyme Activation; Extracellular Space; Macrophage Activation; Macrophages; Mice; Nitric Oxide; Oxidation-Reduction; Receptors, Purinergic P2; Signal Transduction; Temperature; Time Factors | 2000 |
Extracellular ATP formation on vascular endothelial cells is mediated by ecto-nucleotide kinase activities via phosphotransfer reactions.
Topics: 5'-Nucleotidase; Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenylate Kinase; Apyrase; Cells, Cultured; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Kinetics; Luminescent Measurements; Membrane Proteins; Nucleoside-Diphosphate Kinase; Phosphates; Phosphorylation; Phosphotransferases (Phosphate Group Acceptor); Substrate Specificity | 2001 |
Adenosine diphosphate strongly potentiates the ability of the chemokines MDC, TARC, and SDF-1 to stimulate platelet function.
Topics: Adenosine Diphosphate; Apyrase; Blood Platelets; Calcium; Calcium Signaling; Chemokine CCL17; Chemokine CCL22; Chemokine CXCL12; Chemokines, CC; Chemokines, CXC; Collagen; Fibrinogen; Hemorheology; Humans; Indomethacin; Ion Transport; Microscopy, Electron, Scanning; P-Selectin; Platelet Activation; Platelet Adhesiveness; Thrombin | 2001 |
Inhibition of platelet function by administration of MRS2179, a P2Y1 receptor antagonist.
Topics: Adenosine Diphosphate; Alprostadil; Animals; Apyrase; Blood Platelets; Calcium; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Mice; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Radioligand Assay; Rats; Signal Transduction; Thionucleotides | 2001 |
The C-terminal cysteine-rich region dictates specific catalytic properties in chimeras of the ectonucleotidases NTPDase1 and NTPDase2.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acid Sequence; Antigens, CD; Apyrase; Catalytic Domain; Molecular Sequence Data; Protein Engineering; Recombinant Fusion Proteins | 2001 |
Inhibition of platelet aggregation by bovine endocardial apyrase.
Topics: Adenosine Diphosphate; Animals; Apyrase; Cattle; Cells, Cultured; Endocardium; Endothelium; Female; Male; Platelet Aggregation; Rabbits | 1999 |
Soluble apyrases release adp during ATP hydrolysis.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acid Sequence; Animals; Antigens, CD; Apyrase; Electrophoresis, Polyacrylamide Gel; Hydrolysis; Insecta; Molecular Sequence Data; Recombinant Proteins; Solubility | 2001 |
ATP and ADP hydrolysis in fish, chicken and rat synaptosomes.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Chickens; Enzyme Inhibitors; Female; Fishes; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Male; Rats; Rats, Wistar; Synaptosomes; Temperature; Vertebrates | 2001 |
Transient adhesion refractoriness of circulating platelets under shear stress: the role of partial activation and microaggregate formation by suboptimal ADP concentration.
Topics: Adenosine Diphosphate; Animals; Apyrase; Cattle; Extracellular Matrix; Flow Cytometry; Humans; In Vitro Techniques; Platelet Activation; Platelet Adhesiveness; Purinergic P2 Receptor Antagonists; Rats; Stress, Mechanical; Thrombasthenia | 2001 |
Site-directed mutagenesis of human nucleoside triphosphate diphosphohydrolase 3: the importance of residues in the apyrase conserved regions.
Topics: Acid Anhydride Hydrolases; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acid Sequence; Animals; Apyrase; Cations, Divalent; Conserved Sequence; COS Cells; Enzyme Activation; Enzyme Inhibitors; Humans; Hydrolysis; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Substrate Specificity; Transfection; Triazines | 2001 |
Inhibition of the ecto-ATPdiphosphohydrolase of Schistosoma mansoni by thapsigargin.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Calcium; Calcium-Transporting ATPases; Enzyme Inhibitors; Hydrolysis; Magnesium; Plant Extracts; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Schistosoma mansoni; Thapsigargin | 2000 |
Beta-lactam antibiotic-mediated changes in platelet reactivity and vascular endothelial functions.
Topics: Adenosine Diphosphate; Animals; Anti-Bacterial Agents; Aorta, Thoracic; Apyrase; Arachidonic Acid; Aztreonam; Blood Platelets; Cattle; Ceftazidime; Ceftriaxone; Collagen; Endothelium, Vascular; Epoprostenol; Humans; In Vitro Techniques; Platelet Activation; Platelet Aggregation Inhibitors; Radioimmunoassay; Time Factors; Tissue Plasminogen Activator | 2001 |
Characterisation of an ATP diphosphohydrolase (Apyrase, EC 3.6.1.5) activity in Trichomonas vaginalis.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Calcium Chloride; Enzyme Inhibitors; Magnesium Chloride; Substrate Specificity; Trichomonas vaginalis | 2001 |
Nucleotide-evoked relaxation of rat vas deferens--a possible role for endogenous ATP released upon alpha(1)-adrenoceptor stimulation.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscle Relaxation; Norepinephrine; Nucleotides; Potassium; Purinergic P1 Receptor Antagonists; Pyridoxal Phosphate; Pyrophosphatases; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Suramin; Theophylline; Thionucleotides; Triazines; Vas Deferens; Vasoconstrictor Agents | 2001 |
Effect of nitric oxide donors on extracellular ATP, ADP, and AMP catabolism in rat hippocampal synaptosomes.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Apyrase; Extracellular Space; Hippocampus; Male; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Rats; Rats, Wistar; Synaptosomes | 2001 |
Signalling events underlying platelet aggregation induced by the glycoprotein VI agonist convulxin.
Topics: Adenosine Diphosphate; Animals; Apyrase; CD36 Antigens; Crotalid Venoms; Drug Synergism; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Indoles; Indomethacin; Lectins, C-Type; Mice; Phosphatidic Acids; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Serotonin; Signal Transduction; Thromboxane A2 | 2001 |
Phenylalanine and phenylpyruvate inhibit ATP diphosphohydrolase from rat brain cortex.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Cerebral Cortex; Hydrolysis; Kinetics; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Presynaptic Terminals; Rats; Rats, Wistar; Synaptosomes | 2001 |
Kinetic characterization and immunodetection of ecto-ATP diphosphohydrolase (EC 3.6.1.5) in cultured hippocampal neurons.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Cells, Cultured; Hippocampus; Hydrolysis; Immunoblotting; Immunohistochemistry; Kinetics; Neurons; Rats; Rats, Wistar | 2002 |
Transmembrane domains confer different substrate specificities and adenosine diphosphate hydrolysis mechanisms on CD39, CD39L1, and chimeras.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Amino Acid Sequence; Antigens, CD; Apyrase; Detergents; Humans; Hydrolysis; In Vitro Techniques; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleotidases; Octoxynol; Protein Structure, Tertiary; Recombinant Fusion Proteins; Solubility; Substrate Specificity | 2002 |
Characterization and cytochemical localization of an ATP diphosphohydrolase from Leishmania amazonensis promastigotes.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Calcium; Cell Membrane; Enzyme Inhibitors; Female; Hydrogen-Ion Concentration; Leishmania; Levamisole; Mice; Mice, Inbred BALB C; Microscopy, Electron; Molybdenum; Sodium Azide; Substrate Specificity | 2002 |
On-column enzyme-catalyzed microreactions using capillary electrophoresis: quantitative studies.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Apyrase; Bioreactors; Electrophoresis, Capillary; Enzymes; Fructose-Bisphosphate Aldolase; Glucosephosphate Dehydrogenase; Hexokinase; Microchemistry; NAD; Oxidation-Reduction; Reproducibility of Results | 2002 |
ATP diphosphohydrolase (NTPDase 1) in rat hippocampal slices and effect of glutamate on the enzyme activity in different phases of development.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Binding Sites; Female; Glutamic Acid; Hippocampus; Hydrolysis; In Vitro Techniques; Kinetics; Rats; Rats, Wistar | 2002 |
Reversal of thrombin-induced deactivation of CD39/ATPDase in endothelial cells by HMG-CoA reductase inhibition: effects on Rho-GTPase and adenosine nucleotide metabolism.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Antigens, CD; Apyrase; Blood Platelets; Cell Separation; Cells, Cultured; Culture Media, Conditioned; Endothelium, Vascular; Enzyme Reactivators; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinetics; Platelet Aggregation; Pyridines; rho GTP-Binding Proteins; Simvastatin; Thrombin; Time Factors; Umbilical Veins | 2002 |
Roles of Asp54 and Asp213 in Ca2+ utilization by soluble human CD39/ecto-nucleotidase.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Alanine; Amino Acid Sequence; Antigens, CD; Apyrase; Aspartic Acid; Blood Platelets; Calcium; Cations, Divalent; Codon; Humans; Kinetics; Mutagenesis, Site-Directed; Protein Conformation; Recombinant Proteins | 2002 |
Role of extracellular ATP metabolism in regulation of platelet reactivity.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Antigens, CD; Apyrase; Blood Platelets; Dose-Response Relationship, Drug; Drug Antagonism; Humans; Hydrolysis; In Vitro Techniques; Phosphoric Diester Hydrolases; Phosphorus Radioisotopes; Platelet Aggregation; Theobromine | 2002 |
A selective role for phosphatidylinositol 3,4,5-trisphosphate in the Gi-dependent activation of platelet Rap1B.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenergic Agonists; Androstadienes; Animals; Antimetabolites; Apyrase; Blood Platelets; Chromones; Dideoxyadenosine; Enzyme Inhibitors; Epinephrine; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Mice; Mice, Knockout; Morpholines; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates; Phosphoinositide-3 Kinase Inhibitors; Platelet Activation; Platelet Aggregation; Protein Binding; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; rap GTP-Binding Proteins; Receptors, Fc; Receptors, IgG; Second Messenger Systems; Wortmannin | 2003 |
Depolarization of endothelial cells enhances platelet aggregation through oxidative inactivation of endothelial NTPDase.
Topics: Adenosine Diphosphate; Animals; Antigens, CD; Apyrase; Arterioles; Blotting, Western; Cell Line; Cell Survival; Cricetinae; Culture Media, Conditioned; Endothelium, Vascular; Enzyme Repression; Humans; Membrane Potentials; Mesocricetus; Oxidation-Reduction; Phosphates; Platelet Aggregation; Superoxides; Umbilical Veins | 2002 |
In vitro effects of L-arginine and guanidino compounds on NTPDase1 and 5'-nucleotidase activities from rat brain synaptosomes.
Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Arginine; Brain; Guanidines; Homoarginine; Hydrolysis; Male; Osmolar Concentration; Rats; Rats, Wistar; Synaptosomes | 2003 |
Characterization of an ectonucleoside triphosphate diphosphohydrolase 1 activity in alkaline phosphatase-depleted rat osseous plate membranes: possible functional involvement in the calcification process.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alamethicin; Alkaline Phosphatase; Animals; Antigens, CD; Apyrase; Binding Sites; Calcification, Physiologic; Calcium; Catalysis; Growth Plate; Hydrogen-Ion Concentration; Magnesium; Membranes; Rats; Substrate Specificity | 2003 |
Differences in nucleotide-binding site of isoapyrases deduced from tryptophan fluorescence.
Topics: Acrylamide; Adenosine Diphosphate; Adenosine Triphosphate; Apyrase; Binding Sites; Cesium; Iodides; Isoenzymes; Kinetics; Nucleotides; Photobleaching; Solanum tuberosum; Spectrometry, Fluorescence; Substrate Specificity; Tryptophan | 2003 |
Characterization of the NTPDase activities in the mesentery pre- and post-capillary circuits of the guinea pig.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Cholic Acids; Chromatography, High Pressure Liquid; Endothelium, Vascular; Female; Guinea Pigs; In Vitro Techniques; Male; Mesenteric Arteries; Mesenteric Veins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Vasodilation | 2003 |
Effects of phenylalanine and phenylpyruvate on ATP-ADP hydrolysis by rat blood serum.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Hydrolysis; Kinetics; Male; Phenylalanine; Phenylpyruvic Acids; Rats; Rats, Wistar | 2003 |
The effect of stress upon hydrolysis adenine nucleotides in blood serum of rats.
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Apyrase; Hydrolysis; Male; Nucleotidases; Rats; Rats, Wistar; Restraint, Physical; Stress, Psychological | 2003 |
Effects of metronidazole and tinidazole on NTPDase1 and ecto-5'-nucleotidase from intact cells of Trichomonas vaginalis.
Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antitrichomonal Agents; Apyrase; Metronidazole; Tinidazole; Trichomonas vaginalis | 2003 |
Ecto-ATPase and ecto-ATP-diphosphohydrolase are co-localized in rat hippocampal and caudate nucleus synaptic plasma membranes.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Caudate Nucleus; Enzyme Inhibitors; Hippocampus; Hydrolysis; Immunoblotting; Kinetics; Rats; Rats, Wistar; Synaptic Membranes | 2003 |
Beneficial effects of CD39/ecto-nucleoside triphosphate diphosphohydrolase-1 in murine intestinal ischemia-reperfusion injury.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Blood Platelets; Capillaries; Cyclic AMP; Cytokines; Endothelium, Vascular; Gene Deletion; Intestine, Small; Ischemia; Male; Mice; Mice, Inbred C57BL; Microscopy, Video; Oxidative Stress; Permeability; Peroxidase; Platelet Activation; Reperfusion Injury; Time Factors; Vascular Endothelial Growth Factor A | 2004 |
Triatoma infestans apyrases belong to the 5'-nucleotidase family.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Amino Acid Sequence; Animals; Apyrase; Biological Evolution; Blood Platelets; Blotting, Southern; Blotting, Western; Cell Line; Chromatography; Chromatography, Gel; Cloning, Molecular; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Gene Library; Glycosylation; Humans; Insecta; Mass Spectrometry; Molecular Sequence Data; Peptides; Platelet Aggregation; Polymerase Chain Reaction; Recombinant Proteins; Saliva; Sequence Homology, Amino Acid; Triatoma; Trypanosoma cruzi | 2004 |
Enhanced P2X7 activity in human fibroblasts from diabetic patients: a possible pathogenetic mechanism for vascular damage in diabetes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Diphosphate; Adenosine Triphosphate; Apoptosis; Apyrase; Autocrine Communication; Cell Shape; Cytidine Triphosphate; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Fibroblasts; Fibronectins; Gene Expression Regulation; Humans; Interleukin-6; Membrane Potentials; Paracrine Communication; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Uridine Diphosphate; Uridine Triphosphate | 2004 |
NTPDase and 5'-nucleotidase activities in rats with alloxan-induced diabetes.
Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Blood Platelets; Cerebral Cortex; Cholesterol; Diabetes Mellitus, Experimental; Male; Platelet Aggregation; Random Allocation; Rats; Synaptosomes; Triglycerides | 2004 |
3D electron microscopy of the interaction of kinesin with tubulin.
Topics: Adenosine Diphosphate; Animals; Apyrase; Binding Sites; Cryoelectron Microscopy; Fourier Analysis; Hexokinase; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Kinesins; Microscopy, Electron; Microscopy, Electron, Scanning; Microtubule Proteins; Microtubules; Models, Molecular; Molecular Motor Proteins; Paclitaxel; Protein Binding; Protein Conformation; Protein Structure, Secondary; Swine; Tubulin | 1999 |
Ovariectomy and estradiol replacement therapy alters the adenine nucleotide hydrolysis in rat blood serum.
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Apyrase; Dehydroepiandrosterone Sulfate; Estradiol; Female; Gonadal Steroid Hormones; Hormone Replacement Therapy; Hydrolysis; Ovariectomy; Pregnanolone; Rats; Rats, Wistar | 2004 |
Phosphorylation of the sarcoplasmic reticulum Ca(2+)-ATPase from ATP and ATP analogs studied by infrared spectroscopy.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Apyrase; Calcium-Transporting ATPases; Kinetics; Phosphorylation; Protein Binding; Protein Conformation; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Spectroscopy, Fourier Transform Infrared | 2004 |
Biochemical brain markers and purinergic parameters in rat CSF after seizure induced by pentylenetetrazol.
Topics: Adenosine; Adenosine Diphosphate; Animals; Antigens, CD; Apyrase; Biomarkers; Brain; Convulsants; Disease Models, Animal; Female; Guanosine; Guanosine Diphosphate; Hydrolysis; Inosine; Nerve Degeneration; Nerve Growth Factors; Nerve Tissue Proteins; Pentylenetetrazole; Phosphopyruvate Hydratase; Purines; Rats; Rats, Wistar; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Seizures; Time Factors; Up-Regulation | 2004 |
Acetylsalicylic acid inhibits ATP diphosphohydrolase activity by platelets from adult rats.
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Apyrase; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; In Vitro Techniques; Male; Rats; Rosaniline Dyes | 2004 |
ADP acting on P2Y13 receptors is a negative feedback pathway for ATP release from human red blood cells.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Apyrase; Cyclic AMP; Epinephrine; Erythrocyte Membrane; Erythrocytes; Feedback, Physiological; Female; Humans; Male; Microdialysis; Phentolamine; Propranolol; Receptors, Purinergic P2; Reticulocytes; RNA, Messenger; Sus scrofa; Thionucleotides | 2005 |
Characterization of NTPDase (NTPDase1; ecto-apyrase; ecto-diphosphohydrolase; CD39; EC 3.6.1.5) activity in human lymphocytes.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Antigens, CD; Apyrase; Humans; Kinetics; Lymphocytes; Substrate Specificity | 2005 |
Use of helper enzymes for ADP removal in infrared spectroscopic experiments: application to Ca2+-ATPase.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Adenylate Kinase; Apyrase; Calcium; Escherichia coli; Hydrolysis; Kinetics; Models, Chemical; Protein Binding; Spectrophotometry; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared; Time Factors | 2005 |
Hypo-and hyperthyroidism affect the ATP, ADP and AMP hydrolysis in rat hippocampal and cortical slices.
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Antigens, CD; Antithyroid Agents; Apyrase; Cerebral Cortex; Hippocampus; Hydrolysis; Hyperthyroidism; Hypothyroidism; Male; Methimazole; Organ Culture Techniques; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Thyroidectomy; Thyroxine | 2005 |
Degradation of extracellular ATP by the retinal pigment epithelium.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Calcium; Calcium Signaling; Cattle; Cell Line; Enzyme Inhibitors; Extracellular Space; Gene Expression Regulation, Enzymologic; Glucose-6-Phosphate Isomerase; Glycoproteins; Humans; Membrane Proteins; Multienzyme Complexes; Phosphodiesterase I; Phosphoric Diester Hydrolases; Pigment Epithelium of Eye; Purines; Pyrophosphatases; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Reverse Transcriptase Polymerase Chain Reaction | 2005 |
Characterisation of species differences in the platelet ADP and thrombin response.
Topics: Adenosine Diphosphate; Animals; Apyrase; Blood Platelets; Dogs; Dose-Response Relationship, Drug; Female; Fibrinogen; Flow Cytometry; Guinea Pigs; Humans; Male; Mice; Mice, Inbred C57BL; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Reference Values; Species Specificity; Thrombin | 2006 |
Characterization of ATP and ADP hydrolysis activity in rat gastric mucosa.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Calcium; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gastric Mucosa; Hydrogen-Ion Concentration; Hydrolysis; In Vitro Techniques; Magnesium; Male; Rats; Rats, Wistar; Sodium Azide; Substrate Specificity; Suramin; Vanadates | 2005 |
Heterogeneity in extracellular nucleotide hydrolysis among clinical isolates of Trichomonas vaginalis.
Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Culture Media; Dose-Response Relationship, Drug; Iron; Trichomonas vaginalis | 2005 |
Effects of SolCD39, a novel inhibitor of Platelet Aggregation, on Platelet Deposition and Aggregation after PTCA in a Porcine Model.
Topics: Adenosine Diphosphate; Angioplasty, Balloon, Coronary; Animals; Antigens, CD; Apyrase; Blood Coagulation Tests; Collagen; Drug Evaluation, Preclinical; Half-Life; Humans; Models, Animal; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptors, Thrombin; Solubility; Swine | 2005 |
The novel suramin analogue NF864 selectively blocks P2X1 receptors in human platelets with potency in the low nanomolar range.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Apyrase; Blood Platelets; Calcium; Cell Shape; Dose-Response Relationship, Drug; Humans; Least-Squares Analysis; Linear Models; Phenylmercury Compounds; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2Y1; Suramin; Thionucleotides | 2005 |
Ecto-hydrolysis of adenine nucleotides in rat blood platelets are altered by ovariectomy.
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Blood Platelets; Cell Membrane; Enzyme Activation; Estrogen Replacement Therapy; Female; Hydrolysis; Ovariectomy; Rats; Rats, Wistar | 2005 |
Kinetic characterization of ATP diphosphohydrolase and 5'-nucleotidase activities in cells cultured from submandibular salivary glands of rats.
Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Apyrase; Binding Sites; Binding, Competitive; Cations; Cells, Cultured; Hydrolysis; Kinetics; Male; Rats; Rats, Wistar; Submandibular Gland; Time Factors | 2006 |
E-NTPDase 3 (ATP diphosphohydrolase) from cardiomyocytes, activity and expression are modulated by thyroid hormone.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Animals, Newborn; Apyrase; Cells, Cultured; Hydrolysis; Myocytes, Cardiac; Pyrophosphatases; Rats; Rats, Wistar; RNA, Messenger; Triiodothyronine; Up-Regulation | 2006 |
Leishmania amazonensis: Biological and biochemical characterization of ecto-nucleoside triphosphate diphosphohydrolase activities.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Blotting, Western; Female; Flow Cytometry; Humans; Leishmania mexicana; Leishmaniasis, Cutaneous; Macrophages, Peritoneal; Mice; Microscopy, Immunoelectron; Pyrophosphatases | 2006 |
Reconstitution of CD39 in liposomes amplifies nucleoside triphosphate diphosphohydrolase activity and restores thromboregulatory properties.
Topics: Adenosine Diphosphate; Animals; Antigens, CD; Apyrase; Biopsy, Needle; Blotting, Western; Disease Models, Animal; Humans; Immunohistochemistry; Injections, Intravenous; Liposomes; Mice; Mice, Inbred Strains; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Count; Pulmonary Embolism; Reverse Transcriptase Polymerase Chain Reaction; Sensitivity and Specificity; Thromboplastin; Time Factors | 2006 |
Up-regulation of ectonucleotidase activity after cortical stab injury in rats.
Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Astrocytes; Brain; Brain Injuries; Male; Microglia; Rats; Up-Regulation | 2006 |
Inhibition of rat brain ecto-atpase activity by various drugs.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Anti-Anxiety Agents; Anticonvulsants; Apyrase; Brain; Calcium Channel Blockers; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydrolysis; Male; Rats; Rats, Wistar; Receptors, Purinergic P2; Synaptic Membranes | 2006 |
Regulation of death and survival in astrocytes by ADP activating P2Y1 and P2Y12 receptors.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Apoptosis; Apyrase; Astrocytes; Cell Line, Tumor; Cell Survival; Humans; In Situ Nick-End Labeling; Protein Serine-Threonine Kinases; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Thionucleosides; Tumor Necrosis Factor-alpha | 2006 |
Genomic-independent action of thyroid hormones on NTPDase activities in Sertoli cell cultures from congenital hypothyroid rats.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Cells, Cultured; Hypothyroidism; Male; Pyrophosphatases; Rats; Rats, Wistar; Sertoli Cells; Thyroid Hormones | 2006 |
Multiple electrode aggregometry: a new device to measure platelet aggregation in whole blood.
Topics: Adenosine Diphosphate; Anticoagulants; Apyrase; Aspirin; Blood Preservation; Citrates; Collagen; Dose-Response Relationship, Drug; Electric Impedance; Electrodes; Hirudins; Humans; In Vitro Techniques; Peptide Fragments; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Platelet Function Tests; Reference Values; Reproducibility of Results; Sensitivity and Specificity; Sodium Citrate; Time Factors | 2006 |
[Role of adenosine diphosphate in the course of thrombin signal transmission].
Topics: Adenosine Diphosphate; Apyrase; Flow Cytometry; Humans; Oligopeptides; P-Selectin; Peptide Fragments; Platelet Aggregation; Platelet Glycoprotein GPIb-IX Complex; Receptor, PAR-1; Receptors, Thrombin; Signal Transduction; Thrombin; Time Factors | 2006 |
Purines induce directed migration and rapid homing of microglia to injured pyramidal neurons in developing hippocampus.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Animals, Newborn; Apyrase; Brain Injuries; Cell Communication; Cell Count; Cell Movement; Hippocampus; Mice; Mice, Inbred C57BL; Microglia; Microscopy, Confocal; Organ Culture Techniques; Phagocytosis; Pyramidal Cells; Rats; Rats, Sprague-Dawley | 2007 |
Proline induces alterations on nucleotide hydrolysis in synaptosomes from cerebral cortex of rats.
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Brain Diseases, Metabolic, Inborn; Cerebral Cortex; Hydrolysis; Male; Proline; Rats; Rats, Wistar; Synaptosomes | 2007 |
CD39 activity correlates with stage and inhibits platelet reactivity in chronic lymphocytic leukemia.
Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Antigens, CD; Apyrase; B-Lymphocytes; Chromatography, Thin Layer; Female; Flow Cytometry; Gene Expression Regulation, Leukemic; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocyte Subsets; Male; Middle Aged; Platelet Activation; Platelet Aggregation; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocytes | 2007 |
Platelet aggregation studies: autologous platelet-poor plasma inhibits platelet aggregation when added to platelet-rich plasma to normalize platelet count.
Topics: Adenosine Diphosphate; Apyrase; Artifacts; Buffers; Centrifugation; Collagen; Humans; Nephelometry and Turbidimetry; Plasma; Platelet Activating Factor; Platelet Aggregation; Platelet Count; Platelet Function Tests; Platelet-Rich Plasma | 2007 |
Characterization of a novel ADPase in Bothrops jararaca snake venom involved in nucleotide hydrolysis.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Apyrase; Bothrops; Chromatography, High Pressure Liquid; Crotalid Venoms; Kinetics; Metabolic Networks and Pathways; Nucleotides | 2007 |
Vesicular ATP is the predominant cause of intercellular calcium waves in astrocytes.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aniline Compounds; Animals; Apyrase; Astrocytes; Brefeldin A; Calcium; Calcium Signaling; Cells, Cultured; Cytoplasmic Vesicles; Diffusion; Enzyme Inhibitors; Fluorescent Dyes; Hippocampus; Macrolides; Neurons; Paracrine Communication; Proton-Translocating ATPases; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Suramin; Time Factors; Xanthenes | 2007 |
NTPDase and 5'-nucleotidase activities in platelets of human pregnants with a normal or high risk for thrombosis.
Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adult; Antigens, CD; Apyrase; Blood Platelets; Capillary Permeability; Cell Membrane Permeability; Female; Humans; L-Lactate Dehydrogenase; Pregnancy; Pregnancy Complications, Cardiovascular; Risk Factors; Thrombosis | 2007 |
The nucleoside triphosphate diphosphohydrolase-1/CD39 is incorporated into human immunodeficiency type 1 particles, where it remains biologically active.
Topics: Adenosine Diphosphate; Animals; Antigens, CD; Apyrase; Cell Line; HIV-1; Humans; Platelet Aggregation; Virion | 2007 |
Specificity of the ecto-ATPase inhibitor ARL 67156 on human and mouse ectonucleotidases.
Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Dinucleoside Phosphates; Enzyme Inhibitors; Humans; Hydrolysis; Kinetics; Mice; Nucleotidases; Phosphoric Diester Hydrolases; Pyrophosphatases; Recombinant Proteins; Substrate Specificity; Thymidine Monophosphate; Uridine Triphosphate | 2007 |
Ecto-nucleoside triphosphate diphosphohydrolase inhibits ATP- and ADP-induced vasoconstriction.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Dose-Response Relationship, Drug; Male; Rats; Rats, Sprague-Dawley; Vasoconstriction | 2008 |
Inhibition of human and mouse plasma membrane bound NTPDases by P2 receptor antagonists.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Antigens, CD; Aorta, Thoracic; Apyrase; Benzenesulfonates; Cell Membrane; Chlorocebus aethiops; COS Cells; Humans; Hydrolysis; Mice; Mice, Knockout; Purinergic P2 Receptor Antagonists; Recombinant Proteins; Suramin; Transfection; Triazines | 2007 |
Comparison of the effects of unfractionated heparin and the low-molecular-weight heparins dalteparin and enoxaparin on spontaneous platelet aggregation and adenosine diphosphate activity in platelets during the third trimester of pregnancy.
Topics: Adenosine Diphosphate; Adult; Analysis of Variance; Anticoagulants; Apyrase; Blood Platelets; Dalteparin; Enoxaparin; Female; Heparin; Humans; In Vitro Techniques; Platelet Aggregation; Platelet Count; Pregnancy; Pregnancy Trimester, Third | 2007 |
Raised levels of CD39 in leucocytosis result in marked inhibition of ADP-induced platelet aggregation via rapid ADP hydrolysis.
Topics: Adenosine Diphosphate; Antigens, CD; Apyrase; Female; Humans; Hydrolysis; Leukocyte Count; Leukocytes; Leukocytosis; Male; Platelet Aggregation | 2008 |
Transmembrane domain interactions affect the stability of the extracellular domain of the human NTPDase 2.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Apyrase; Cell Membrane; Chickens; Enzyme Activation; Humans; Octoxynol; Polyethylene Glycols; Protein Structure, Tertiary; Recombinant Fusion Proteins; Substrate Specificity; Temperature | 2008 |
Enzymatic properties of an ecto-nucleoside triphosphate diphosphohydrolase from Legionella pneumophila: substrate specificity and requirement for virulence.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Catalysis; Cell Line; Cytidine; Enzyme Activation; Guanosine Diphosphate; Humans; Hydrogen-Ion Concentration; Hydrolysis; Legionella pneumophila; Metals; Mice; Multienzyme Complexes; Mutation; Substrate Specificity; Uridine | 2008 |
Blebbistatin stabilizes the helical order of myosin filaments by promoting the switch 2 closed state.
Topics: Actins; Adenosine Diphosphate; Animals; Apyrase; Arachnida; Heterocyclic Compounds, 4 or More Rings; Muscles; Myosins; Phosphates; Protein Binding | 2008 |
Effect of high glucose levels in human platelet NTPDase and 5'-nucleotidase activities.
Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Triphosphate; Adult; Aged; Albuminuria; Antigens, CD; Apyrase; Blood Glucose; Blood Platelets; C-Reactive Protein; Cholesterol; Diabetes Complications; Diabetes Mellitus; Glucose; Humans; Hypertension; Middle Aged; Nucleoside-Triphosphatase | 2008 |
A membrane network of receptors and enzymes for adenine nucleotides and nucleosides.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Cell Line; Cell Membrane; Fluorescence; Fluorescence Resonance Energy Transfer; Humans; Hydrolysis; Immunoprecipitation; Membrane Potentials; Mice; Nucleosides; Protein Binding; Protein Subunits; Rats; Receptors, G-Protein-Coupled; Receptors, Purinergic; Recombinant Fusion Proteins; Reproducibility of Results | 2009 |
GS52 ecto-apyrase plays a critical role during soybean nodulation.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Apyrase; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Gene Silencing; Glycine max; Molecular Sequence Data; Nucleotides; Pisum sativum; Plant Proteins; Plant Roots; Pyrophosphatases; RNA Interference; RNA, Messenger; Solanum tuberosum; Transcription, Genetic | 2009 |
Loss of purinergic vascular regulation in the colon during colitis is associated with upregulation of CD39.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antigens, CD; Antigens, Differentiation; Apyrase; Arterioles; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Electric Stimulation; Enzyme Inhibitors; Macrophages; Male; Mice; RNA, Messenger; Splanchnic Circulation; Submucous Plexus; Sympathetic Nervous System; Up-Regulation; Vasoconstriction | 2009 |
ADPase activity of recombinantly expressed thermotolerant ATPases may be caused by copurification of adenylate kinase of Escherichia coli.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenylate Kinase; Apyrase; Biocatalysis; Chromatography, Ion Exchange; Enzyme Stability; Escherichia coli; Gene Expression; Hydrolysis; Nucleotides; Protein Binding; Protein Conformation; Recombinant Proteins; Temperature | 2009 |
Self-regulation of inflammatory cell trafficking in mice by the leukocyte surface apyrase CD39.
Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antibodies, Monoclonal; Antigens, CD; Apyrase; Bone Marrow Transplantation; Brain Ischemia; Cell Line, Tumor; Cell Movement; Endothelial Cells; Enzyme Inhibitors; Leukocytes; Macrophage-1 Antigen; Macrophages; Mice; Mice, Inbred Strains; Mice, Knockout; Monocytes; Neutrophils; Platelet Activation; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; RNA Interference; Transplantation Chimera | 2009 |
Time-course changes in ectonucleotidase activities during experimental autoimmune encephalomyelitis.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Apyrase; Cell Membrane; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Multiple Sclerosis; Rats; Rats, Inbred Strains; Spinal Cord; Time Factors | 2009 |
Activities of the enzymes that hydrolyze adenine nucleotides in platelets from multiple sclerosis patients.
Topics: Adenine Nucleotides; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Triphosphate; Adult; Antigens, CD; Apyrase; Blood Platelets; Female; Flow Cytometry; Humans; Hydrolysis; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Nucleotidases; Phosphoric Diester Hydrolases; Platelet Aggregation | 2010 |
Apyrase treatment prevents ischemia-reperfusion injury in rat lung isografts.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apoptosis; Apyrase; Bronchopulmonary Sequestration; Chemokines; Cytokines; Endothelium, Vascular; Leukocyte Count; Lung Transplantation; Male; Neutrophils; Peroxidase; Pulmonary Edema; Rats; Rats, Inbred F344; Recombinant Proteins; Reperfusion Injury | 2009 |
Homocysteine decreases extracellular nucleotide hydrolysis in rat platelets.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Apyrase; Blood Platelets; Catalysis; Dose-Response Relationship, Drug; Extracellular Space; Homocysteine; Hydrolysis; Male; Rats; Rats, Wistar; Time Factors | 2010 |
The activity and expression of NTPDase is altered in lymphocytes of multiple sclerosis patients.
Topics: Adenosine Deaminase; Adenosine Diphosphate; Adenosine Triphosphate; Adult; Aged; Antigens, CD; Apyrase; Case-Control Studies; Female; Gene Expression Regulation, Enzymologic; Humans; Lymphocytes; Male; Middle Aged; Multiple Sclerosis; Recurrence | 2010 |
Deletion of CD39 on natural killer cells attenuates hepatic ischemia/reperfusion injury in mice.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Killer Cells, Natural; Mice; Mice, Inbred C57BL; Receptors, Purinergic P2; Reperfusion Injury | 2010 |
Nucleotide degrading enzymes in platelets from uterine cervical neoplasia patients treated with conization or radiotherapy.
Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adult; Antigens, CD; Apyrase; Blood Coagulation Tests; Blood Platelets; Conization; Female; Humans; Middle Aged; Platelet Aggregation; Platelet Count; Platelet-Rich Plasma; Uterine Cervical Neoplasms; Vaginal Smears | 2010 |
Enzymes that hydrolyze adenine nucleotides in lymphocytes and platelets of immunosuppressed rats.
Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Blood Platelets; Humans; Hydrolysis; Immune Tolerance; Lymphocytes; Male; Rats; Rats, Wistar | 2010 |
ADP mediates inhibition of insulin secretion by activation of P2Y13 receptors in mice.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Cell Line; Cells, Cultured; Cyclic AMP; Female; Glucagon; In Vitro Techniques; Insulin; Insulin Secretion; Insulin-Secreting Cells; Islets of Langerhans; Mice; Polymerase Chain Reaction; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Thionucleotides | 2010 |
Autocrine purinergic receptor signaling is essential for macrophage chemotaxis.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Cells, Cultured; Chemotaxis; Complement C5a; Feedback, Physiological; Female; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Atomic Force; Models, Biological; Monocytes; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Receptors, Purinergic P2Y2; Signal Transduction | 2010 |
Both the stimulation and inhibition of root hair growth induced by extracellular nucleotides in Arabidopsis are mediated by nitric oxide and reactive oxygen species.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Apyrase; Arabidopsis; Hydrogen Peroxide; Nitric Oxide; Nucleotides; Plant Roots; Reactive Oxygen Species; RNA Interference; Thionucleotides | 2010 |
24-hour temporal pattern of NTPDase and 5'-nucleotidase enzymes in rat blood serum.
Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Apyrase; Circadian Rhythm; Corticosterone; Kinetics; Male; Melatonin; Nucleotidases; Rats; Rats, Wistar | 2010 |
Inhibition of vascular ectonucleotidase activities by the pro-drugs ticlopidine and clopidogrel favours platelet aggregation.
Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Antigens, CD; Apyrase; Chlorocebus aethiops; Clopidogrel; COS Cells; Dose-Response Relationship, Drug; Endothelial Cells; Humans; Hydrolysis; Platelet Aggregation; Platelet Aggregation Inhibitors; Prodrugs; Rats; Species Specificity; Ticlopidine; Umbilical Veins | 2010 |
A calcium-activated apyrase from Teladorsagia circumcincta: an excretory/secretory antigen capable of modulating host immune responses?
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Amino Acid Sequence; Animals; Antigens, Helminth; Apyrase; Calcium; Cations, Divalent; DNA, Complementary; DNA, Helminth; Enzyme Activators; Gene Expression Profiling; Helminth Proteins; Molecular Sequence Data; Ostertagia; Recombinant Proteins; Sequence Homology, Amino Acid; Sheep; Sheep Diseases; Trichostrongyloidea; Trichostrongyloidiasis | 2011 |
Purinergic signals regulate daily S-phase cell activity in the ciliary marginal zone of the zebrafish retina.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Cell Differentiation; Cell Nucleus; Circadian Clocks; Enzyme Inhibitors; Extracellular Space; Hexokinase; Photoperiod; Purinergic P2Y Receptor Antagonists; Pyrophosphatases; Receptors, Purinergic P2Y1; Retina; RNA, Messenger; S Phase; Signal Transduction; Thionucleotides; Zebrafish | 2011 |
Altered purinergic signaling in CD73-deficient mice inhibits tumor progression.
Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Triphosphatases; Animals; Apyrase; Cell Proliferation; Disease Progression; Interferon-gamma; Lectins, C-Type; Lymphocytes; Lymphocytes, Tumor-Infiltrating; Macrophages; Mannose Receptor; Mannose-Binding Lectins; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Knockout; Neoplasm Metastasis; Nitric Oxide Synthase Type II; Purines; Receptors, Cell Surface; RNA, Messenger; Signal Transduction; T-Lymphocytes, Regulatory | 2011 |
Evidence of platelet activation at medically used hypothermia and mechanistic data indicating ADP as a key mediator and therapeutic target.
Topics: Adenosine Diphosphate; Analysis of Variance; Animals; Antigens, CD; Apyrase; Blood Platelets; Fibrinogen; Fibrinolytic Agents; Humans; Hydrolysis; Hypothermia, Induced; Leukopenia; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; P-Selectin; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIb-IX Complex; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Recombinant Proteins; Thrombocytopenia; Thrombosis; von Willebrand Factor | 2011 |
Extracellular nucleotides and apyrases regulate stomatal aperture in Arabidopsis.
Topics: Abscisic Acid; Adenosine Diphosphate; Adenosine Triphosphate; Apyrase; Arabidopsis; Arabidopsis Proteins; Enzyme Inhibitors; Extracellular Space; Gene Expression Regulation, Plant; Hydrogen Peroxide; Light; Models, Biological; Nitric Oxide; Nucleotides; Plant Stomata; Promoter Regions, Genetic; Pyridoxal Phosphate; RNA Interference; Thionucleotides; Triazines | 2011 |
Chronic hypoxia impairs extracellular nucleotide metabolism and barrier function in pulmonary artery vasa vasorum endothelial cells.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Analysis of Variance; Animals; Animals, Newborn; Antigens, CD; Apyrase; Blotting, Western; Capillary Permeability; Cattle; Cell Proliferation; Cyclic AMP; Dextrans; DNA Primers; Endothelial Cells; Fluorescein-5-isothiocyanate; Hypoxia; Neovascularization, Pathologic; Pulmonary Artery; Regression Analysis; Reverse Transcriptase Polymerase Chain Reaction; Vasa Vasorum | 2011 |
CD73-generated extracellular adenosine in chronic lymphocytic leukemia creates local conditions counteracting drug-induced cell death.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Antigens, CD; Antineoplastic Agents, Phytogenic; Apyrase; Autocrine Communication; Cell Death; Cell Differentiation; Cell Movement; Cell Survival; Etoposide; Extracellular Space; GPI-Linked Proteins; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Paracrine Communication; Receptor, Adenosine A2A; Tumor Cells, Cultured | 2011 |
Platelet adhesion and degranulation induce pro-survival and pro-angiogenic signalling in ovarian cancer cells.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Apyrase; Arachidonic Acid; Cell Degranulation; Cell Survival; Drug Synergism; Epithelial-Mesenchymal Transition; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Neovascularization, Pathologic; Oligonucleotide Array Sequence Analysis; Ovarian Neoplasms; Peptide Fragments; Platelet Adhesiveness; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Receptors, Thrombin; Reproducibility of Results; Signal Transduction | 2011 |
Crystallographic evidence for a domain motion in rat nucleoside triphosphate diphosphohydrolase (NTPDase) 1.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Calorimetry; Crystallography, X-Ray; Kinetics; Models, Molecular; Protein Conformation; Protein Structure, Tertiary; Rats | 2012 |
Metabolism of circulating ADP in the bloodstream is mediated via integrated actions of soluble adenylate kinase-1 and NTPDase1/CD39 activities.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylate Kinase; Animals; Antigens, CD; Apyrase; Humans; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Skeletal | 2012 |
Increased NTPDase activity in lymphocytes during experimental sepsis.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Cell Death; Cell Proliferation; Disease Models, Animal; Female; Hydrolysis; Immune System; Leukocytes, Mononuclear; Lymphocytes; Male; Nucleotides; Rats; Rats, Wistar; Sepsis; Tissue Distribution | 2012 |
Mechanical stress-induced interleukin-1beta expression through adenosine triphosphate/P2X7 receptor activation in human periodontal ligament cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Diphosphate; Adenosine Triphosphate; Apyrase; Benzenesulfonates; Calcium Channel Blockers; Calcium Signaling; Cell Culture Techniques; Cell Survival; Cells, Cultured; Coloring Agents; Dactinomycin; Homeostasis; Humans; Interleukin-1beta; Luminescent Measurements; Periodontal Ligament; Purinergic P2X Receptor Antagonists; Receptors, Purinergic P2X7; RNA, Small Interfering; Signal Transduction; Stress, Mechanical; Suramin; Tetrazolium Salts; Thiazoles; Time Factors; Up-Regulation | 2013 |
A study of the imbalance in B cell-expressed nucleoside triphosphate diphosphohydrolase 1-induced ADP degradation in graft injury during acute antibody-mediated rejection.
Topics: Acute Disease; Adenosine Diphosphate; Animals; Antigens, CD; Apyrase; B-Lymphocytes; Disease Models, Animal; Graft Rejection; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Platelet Activation; RNA, Messenger; Skin Transplantation | 2012 |
ATP and ADP hydrolysis in cell membranes from rat myometrium.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Catalytic Domain; Cell Membrane; Female; Hydrolysis; Kinetics; Myometrium; Rats; Rats, Wistar | 2012 |
Activities of enzymes that hydrolyze adenine nucleotides in lymphocytes from patients with rheumatoid arthritis.
Topics: Adenosine Deaminase; Adenosine Diphosphate; Adenosine Triphosphate; Adult; Antigens, CD; Apyrase; Arthritis, Rheumatoid; Case-Control Studies; Cells, Cultured; Enzyme Assays; Female; Humans; Lymphocytes; Male; Middle Aged | 2013 |
Delayed targeting of CD39 to activated platelet GPIIb/IIIa via a single-chain antibody: breaking the link between antithrombotic potency and bleeding?
Topics: Adenosine Diphosphate; Animals; Antigens, CD; Apyrase; Blood Platelets; Drug Delivery Systems; Fibrinolytic Agents; Humans; Male; Mice; Mice, Inbred C57BL; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Recombinant Fusion Proteins; Single-Chain Antibodies; Thrombosis | 2013 |
8-BuS-ATP derivatives as specific NTPDase1 inhibitors.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Chlorocebus aethiops; COS Cells; Enzyme Inhibitors; Human Umbilical Vein Endothelial Cells; Humans; Mice; Platelet Aggregation; Rats; Species Specificity | 2013 |
Gravity loading induces adenosine triphosphate release and phosphorylation of extracellular signal-regulated kinases in human periodontal ligament cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Apyrase; Calcium; Cell Culture Techniques; Cells, Cultured; Centrifugation; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Gingiva; Gravitation; Humans; Periodontal Ligament; Phosphorylation; Purinergic Agonists; Purinergic Antagonists; Purinergic P2X Receptor Antagonists; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2; Signal Transduction; Stress, Mechanical; Suramin | 2014 |
Kindlin-2 regulates hemostasis by controlling endothelial cell-surface expression of ADP/AMP catabolic enzymes via a clathrin-dependent mechanism.
Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Antigens, CD; Apyrase; Blood Platelets; Cell Membrane; Clathrin; Cytoskeletal Proteins; Endothelial Cells; Female; Flow Cytometry; Hemostasis; Immunoprecipitation; Male; Mice; Mice, Knockout; Muscle Proteins; Platelet Aggregation; Protein Transport; Surface Plasmon Resonance | 2013 |
The ATP/ADP substrate specificity switch between Toxoplasma gondii NTPDase1 and NTPDase3 is caused by an altered mode of binding of the substrate base.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Antigens, CD; Apyrase; Binding Sites; Models, Molecular; Pyrophosphatases; Substrate Specificity; Toxoplasma | 2013 |
Inhibition of CD73 stimulates the migration and invasion of B16F10 melanoma cells in vitro, but results in impaired angiogenesis and reduced melanoma growth in vivo.
Topics: 5'-Nucleotidase; Adenosine Diphosphate; Animals; Antigens, CD; Apyrase; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Extracellular Matrix Proteins; HEK293 Cells; Humans; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Neoplasm Invasiveness; Neovascularization, Pathologic; Purinergic P1 Receptor Agonists | 2014 |
Schistosome apyrase SmATPDase1, but not SmATPDase2, hydrolyses exogenous ATP and ADP.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Host-Parasite Interactions; Isoenzymes; Molecular Sequence Data; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Schistosoma mansoni; Schistosomiasis mansoni; Transcriptome; Transfection | 2014 |
Optimizing human apyrase to treat arterial thrombosis and limit reperfusion injury without increasing bleeding risk.
Topics: Adenosine Diphosphate; Animals; Apyrase; Clopidogrel; Coronary Circulation; Dogs; Fibrinolysis; Hemorrhage; Humans; Mice, Inbred C57BL; Myocardial Infarction; Myocardial Reperfusion Injury; Piperazines; Platelet Aggregation; Prasugrel Hydrochloride; Risk Factors; Thiophenes; Thrombosis; Ticlopidine; Time Factors; Tissue Plasminogen Activator; Treatment Outcome; Vascular Patency | 2014 |
Characterization of circulating microparticle-associated CD39 family ecto-nucleotidases in human plasma.
Topics: Adenosine Diphosphate; Antigens, CD; Apyrase; Blotting, Western; Cell-Derived Microparticles; Chromatography, Gel; Flow Cytometry; Humans | 2014 |
Defective PDI release from platelets and endothelial cells impairs thrombus formation in Hermansky-Pudlak syndrome.
Topics: Adenosine Diphosphate; Animals; Apyrase; Blood Platelets; Cell Degranulation; Disease Models, Animal; Endothelial Cells; Exocytosis; Female; Fibrin; Hermanski-Pudlak Syndrome; Human Umbilical Vein Endothelial Cells; Humans; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Platelet Aggregation; Protein Disulfide-Isomerases; RNA, Small Interfering; Thrombin; Thrombosis; Vesicular Transport Proteins | 2015 |
Aberrant circulating levels of purinergic signaling markers are associated with several key aspects of peripheral atherosclerosis and thrombosis.
Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Triphosphate; Adult; Age Factors; Aged; Aged, 80 and over; Alkaline Phosphatase; Angiotensin-Converting Enzyme Inhibitors; Antigens, CD; Apyrase; Artifacts; Atherosclerosis; Biomarkers; Chronic Disease; Comorbidity; Disease Progression; Drug Utilization; Female; Finland; GPI-Linked Proteins; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Hypoxia; Male; Middle Aged; Models, Cardiovascular; Peripheral Arterial Disease; Purinergic P2Y Receptor Antagonists; Risk Factors; Second Messenger Systems; Smoking; Thrombophilia | 2015 |
Different danger signals differently impact on microglial proliferation through alterations of ATP release and extracellular metabolism.
Topics: 5'-Nucleotidase; Adenosine; Adenosine A2 Receptor Antagonists; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Apyrase; Cell Line; Cell Proliferation; Cells, Cultured; Enzyme Inhibitors; Extracellular Space; Glutamic Acid; Lipopolysaccharides; Mice, Inbred C57BL; Microglia; Pyrimidines; Receptors, Adenosine A2; Triazoles | 2015 |
Flow-dependent expression of ectonucleotide tri(di)phosphohydrolase-1 and suppression of atherosclerosis.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apolipoproteins E; Apyrase; Atherosclerosis; Blood Flow Velocity; Blood Platelets; Dietary Fats; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Human Umbilical Vein Endothelial Cells; Humans; Kruppel-Like Transcription Factors; Mice; Mice, Knockout; Plaque, Atherosclerotic; Platelet Activation; Response Elements; Shear Strength | 2015 |
Drospirenone enhances GPIb-IX-V-mediated platelet activation.
Topics: Adenosine Diphosphate; Androstenes; Apyrase; Blood Coagulation; Blood Coagulation Tests; Blood Platelets; Contraceptive Agents, Female; Cyclooxygenase Inhibitors; Humans; Indomethacin; Membrane Proteins; Platelet Activation; Platelet Glycoprotein GPIb-IX Complex; Receptors, Progesterone; Thromboxane A2; von Willebrand Factor | 2015 |
Biochemical characterization of Arabidopsis APYRASE family reveals their roles in regulating endomembrane NDP/NMP homoeostasis.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Apyrase; Arabidopsis; Arabidopsis Proteins; Endoplasmic Reticulum; Endosomes; Gene Knockout Techniques; Genetic Complementation Test; Golgi Apparatus; Homeostasis; Immunoblotting; Intracellular Membranes; Luminescent Proteins; Multigene Family; Phylogeny; Plants, Genetically Modified; Pyrophosphatases; Reverse Transcriptase Polymerase Chain Reaction; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2015 |
Altered purinergic signaling in the tumor associated immunologic microenvironment in metastasized non-small-cell lung cancer.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aged; Antigens, CD; Apyrase; Bronchoalveolar Lavage Fluid; Carcinoma, Non-Small-Cell Lung; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pulmonary Disease, Chronic Obstructive; Receptors, Purinergic; Signal Transduction; Tumor Microenvironment | 2015 |
Altered E-NTPDase/E-ADA activities and CD39 expression in platelets of sickle cell anemia patients.
Topics: 5'-Nucleotidase; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adolescent; Adult; Anemia, Sickle Cell; Antigens, CD; Apyrase; Blood Platelets; Case-Control Studies; Female; Flow Cytometry; GPI-Linked Proteins; Humans; Male; Young Adult | 2016 |
Role of the CD39/CD73 Purinergic Pathway in Modulating Arterial Thrombosis in Mice.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Arterial Occlusive Diseases; Blood Coagulation; Bone Marrow Transplantation; Chlorides; Disease Models, Animal; Endothelial Cells; Ferric Compounds; Genetic Predisposition to Disease; HEK293 Cells; Humans; Hydrolysis; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Monocytes; Phenotype; Platelet Activation; Thrombosis; Time Factors; Transfection | 2016 |
Red Wine Inhibits Aggregation and Increases ATP-diphosphohydrolase (CD39) Activity of Rat Platelets in Vitro.
Topics: Adenosine Diphosphate; Animals; Antigens, CD; Apyrase; Blood Platelets; Diabetes Mellitus, Experimental; Humans; Male; Platelet Aggregation; Rats; Rats, Wistar; Wine | 2016 |
Underlying mechanism and specific prevention of hemolysis-induced platelet activation.
Topics: Adenosine Diphosphate; Adult; Aged; Apyrase; Blood Group Incompatibility; Blood Platelets; Clopidogrel; Female; Hemolysis; Humans; Male; Middle Aged; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Receptors, Purinergic P2Y12; Ticlopidine | 2017 |
Purinergic enzymatic activities in lymphocytes and cardiomyocytes of mice acutely infected by Trypanosoma cruzi modulating the inflammatory responses.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Chagas Disease; Disease Models, Animal; Female; Heart; Hematologic Tests; Hydrolysis; Lymphocytes; Mice; Myocardium; Myocytes, Cardiac; Parasitemia; Purines; Trypanosoma cruzi | 2017 |
Characterization of E-NTPDase (EC 3.6.1.5) activity in hepatic lymphocytes: A different activity profile from peripheral lymphocytes.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Blood Cells; Calcium; Cations, Divalent; Cell Separation; Enzyme Assays; Enzyme Inhibitors; Gene Expression; Hydrogen-Ion Concentration; Kinetics; Liver; Lymphocytes; Male; Organ Specificity; Ouabain; Rats; Rats, Wistar; Sodium Azide; Substrate Specificity; Suramin; Vanadates | 2017 |
Defective ATP breakdown activity related to an ENTPD1 gene mutation demonstrated using
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adult; Antigens, CD; Apyrase; Codon, Terminator; Enzyme Assays; Female; Humans; Hydrolysis; Leukocytes, Mononuclear; Magnetic Resonance Spectroscopy; Male; Middle Aged; Mutation; Phosphates; Phosphorus Radioisotopes | 2017 |
Nucleotide transmitters ATP and ADP mediate intercellular calcium wave communication via P2Y12/13 receptors among BV-2 microglia.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Biomechanical Phenomena; Boron Compounds; Calcium; Calcium Signaling; Cell Communication; Cell Line, Transformed; Gene Expression; Inositol Phosphates; Mechanotransduction, Cellular; Mice; Microglia; Molecular Imaging; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Suramin; Thapsigargin | 2017 |
Increased degradation of ATP is driven by memory regulatory T cells in kidney transplantation tolerance.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adult; Aged; Apyrase; Case-Control Studies; Cells, Cultured; Energy Metabolism; Female; Graft Rejection; Graft Survival; Humans; Hydrolysis; Immunologic Memory; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; T-Lymphocytes, Regulatory; Transplantation Tolerance; Young Adult | 2018 |
Endothelial cells cope with hypoxia-induced depletion of ATP via activation of cellular purine turnover and phosphotransfer networks.
Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Cattle; Cell Hypoxia; GPI-Linked Proteins; Human Umbilical Vein Endothelial Cells; Humans; Ribosomal Protein S6 Kinases, 70-kDa; TOR Serine-Threonine Kinases; Tumor Suppressor Protein p53 | 2018 |
The Essential Ectoenzyme SmNPP5 from the Human Intravascular Parasite Schistosoma mansoni is an ADPase and a Potent Inhibitor of Platelet Aggregation.
Topics: Adenosine Diphosphate; Animals; Apyrase; Blood Platelets; Blood Vessels; Female; Helminth Proteins; Humans; Male; Mice; Phosphoric Diester Hydrolases; Platelet Aggregation Inhibitors; Pyrophosphatases; Schistosoma mansoni; Schistosomiasis mansoni; Virulence Factors | 2018 |
Mechanism of Nucleoside Triphosphate Diphosphohydrolase-1-Associated Imbalance in Adenosine Diphosphate Degradation, B-Cell Activation, and Related Injury During Acute Antibody-Mediated Rejection.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; B-Lymphocytes; Cell Size; Graft Rejection; Lymphocyte Activation; Male; Mice; Mice, Nude; Platelet Activation; RNA, Messenger; Skin Transplantation | 2018 |
Adenylate cyclase inhibition is required for normal redistribution of platelet surface GPIb in response to PAR1 activation.
Topics: Adenosine Diphosphate; Adenylyl Cyclases; Apyrase; Blood Platelets; Humans; Peptide Fragments; Platelet Glycoprotein GPIb-IX Complex; Receptor, PAR-1; Receptors, Purinergic P2Y12; Thrombin | 2019 |
Tuning the Thromboinflammatory Response to Venous Flow Interruption by the Ectonucleotidase CD39.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Blood Platelets; Cell Adhesion; Chemotaxis, Leukocyte; Gene Expression Regulation; Gene Regulatory Networks; Hemorheology; Ligation; Mice; Mice, Inbred C57BL; Mice, Knockout; P-Selectin; Receptors, Purinergic P2Y1; Vasculitis; Vena Cava, Inferior; Venous Thrombosis; von Willebrand Factor | 2019 |
CD133
Topics: AC133 Antigen; Adenosine Diphosphate; Antigens, CD; Apyrase; Blood Platelets; Cell Communication; Endothelial Cells; Endothelium, Vascular; Fibroblasts; Hematopoietic Stem Cells; Humans; Liver Regeneration; Platelet Activation; Platelet Aggregation | 2019 |
Number of Circulating CD 73-Expressing Lymphocytes Correlates With Survival After Cardiac Arrest.
Topics: 5'-Nucleotidase; Adenosine A2 Receptor Antagonists; Adenosine Diphosphate; Adenosine Monophosphate; Aged; Antigens, CD; Apyrase; Cardiopulmonary Resuscitation; Case-Control Studies; Enzyme Inhibitors; Female; Heart Arrest; Humans; In Vitro Techniques; Leukocyte Count; Lymphocytes; Male; Middle Aged; Myeloid Cells; Prognosis; Reactive Oxygen Species; Triazines; Triazoles; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2019 |
Monitoring and characterizing soluble and membrane-bound ectonucleotidases CD73 and CD39.
Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Apyrase; Cell Membrane; GPI-Linked Proteins; Humans; Jurkat Cells; Neoplasm Proteins; Neoplasms; Solubility | 2019 |
Biochemical analysis of ectonucleotidases on primary rat vascular smooth muscle cells and in silico investigation of their role in vascular diseases.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Antigens, CD; Aorta; Apyrase; Computer Simulation; GPI-Linked Proteins; Mice; Muscle, Smooth, Vascular; Nucleotides; Rats; Rats, Wistar; Vascular Diseases | 2020 |
Detection of CD39 and a Highly Glycosylated Isoform of Soluble CD73 in the Plasma of Patients with Cervical Cancer: Correlation with Disease Progression.
Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Monophosphate; Adult; Antigens, CD; Apyrase; Enzyme-Linked Immunosorbent Assay; Female; Humans; Uterine Cervical Neoplasms | 2020 |
Crowding within synaptic junctions influences the degradation of nucleotides by CD39 and CD73 ectonucleotidases.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Apyrase; Synapses | 2022 |
Role of CD39 in COVID-19 Severity: Dysregulation of Purinergic Signaling and Thromboinflammation.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Apyrase; Biomarkers; Blood Platelets; Cell Hypoxia; COVID-19; Critical Care; Female; Humans; Influenza A virus; Influenza, Human; Length of Stay; Male; Middle Aged; Platelet Activation; Prognosis; Prospective Studies; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y; SARS-CoV-2; Severity of Illness Index; Signal Transduction; Thromboinflammation; Ticagrelor | 2022 |
ATPergic signaling disruption in human sepsis as a potential source of biomarkers for clinical use.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Apyrase; Biomarkers; Humans; Sepsis; Shock, Septic | 2023 |
Human soluble CD39 displays substrate inhibition in a substrate-specific manner.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Apyrase; Humans; Uridine Diphosphate | 2023 |