adenosine diphosphate has been researched along with adenosine in 957 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 454 (47.44) | 18.7374 |
| 1990's | 224 (23.41) | 18.2507 |
| 2000's | 141 (14.73) | 29.6817 |
| 2010's | 102 (10.66) | 24.3611 |
| 2020's | 36 (3.76) | 2.80 |
| Authors | Studies |
|---|---|
| Jones, M; Milliner, KJ; Rana, KK; Ward, JG; Young, RC | 1 |
| Boyer, JL; Brizzolara, AL; Burnstock, G; Fischer, B; Harden, TK; Hoyle, CH; Jacobson, KA; Knight, GE; Ziganshin, AU; Zimmet, J | 1 |
| Dobrusin, EM; Fry, DW; Haske, T; McNamara, DJ; Singh, J; Whitty, A | 1 |
| Blackburn, GM; Hagemann, J; Hohmeier, N; Lempka, M; Verspohl, EJ | 1 |
| Borgognoni, J; Clay, A; Daniels, Z; Dokurno, P; Drysdale, MJ; Foloppe, N; Francis, GL; Graham, CJ; Howes, R; Macias, AT; Massey, AJ; Murray, JB; Parsons, R; Shaw, T; Surgenor, AE; Terry, L; Wang, Y; Williamson, DS; Wood, M | 1 |
| Bhave, DP; Carroll, KS; Hong, JA | 1 |
| Bing, T; Chang, T; Liu, X; Qi, C; Shangguan, D; Zhang, N | 1 |
| Azran, S; Danino, O; Dixit, M; Fischer, B; Förster, D; Kenigsberg, S; Major, DT; Reiser, G; Singh, V | 1 |
| Barbeau, O; Burke, R; Cheeseman, MD; Collins, I; Dobson, S; Jeganathan, F; Jones, AM; Jones, K; Kadi, N; Rowlands, M; van Montfort, RL; Westwood, IM; Workman, P | 1 |
| Ide, M; Kamikawa, T; Kashiwagi, H; Matsuo, A; Miura, T; Morikami, K; Muraoka, T; Nishihara, M | 1 |
| Carlson, EE; Goswami, M; Wilke, KE | 1 |
| Barankiewicz, J; Jezewska, MM | 1 |
| Born, GV; Cusack, NJ | 1 |
| Ivanova, GS; Kagan, ZS; Krupianko, VI | 1 |
| Born, GV; Cusack, NJ; Hickman, ME | 1 |
| Holan, J; Kubisz, P; Stránska, M; Suranová, J | 1 |
| Lewis, GP; Lieberman, GE; Peters, TJ | 1 |
| Dozi-Vassiliades, J; Kokolis, N; Tsiamitas, C | 1 |
| Kinlough-Rathbone, RL; Mustard, JF; Packham, MA; Perry, DW; Regoeczi, E | 1 |
| Born, GV; Dearnley, R; Foulks, JG; Sharp, DE | 1 |
| Berne, RM; Degenring, FH; Rubio, R | 1 |
| Hartmann, W; Kluge, H; Ring, U; Wieczorek, V; Zahlten, W | 1 |
| Degenring, FH | 1 |
| Kutas, J; Mozsik, G; Vizi, F | 1 |
| Berne, RM; Curnish, RR; Degenring, FH; Rubio, R | 1 |
| Colman, RF; Mansour, TE | 1 |
| Kostopoulos, GK; Limacher, JJ; Phillis, JW | 1 |
| Bishop, GA; Rozenberg, MC | 1 |
| Berne, RM; Mustafa, SJ; Rubio, R | 2 |
| Belamarich, FA; Shepro, D; Stiller, RA | 1 |
| Ribeiro, JA; Walker, J | 1 |
| Rosenberg, JC; Sell, TL | 1 |
| Colman, RF; Pal, PK; Wechter, WJ | 1 |
| Haslam, RJ; Rosson, GM | 1 |
| Isaksson, O; Rosberg, S; Selstam, G | 1 |
| CoFrancesco, E; Deliliers, GL; Ferrari, R; Pogliani, E; Pozzoli, E; Praga, C | 1 |
| Born, GV; Caen, JP; D'Auriac, GA; Meyer, P; Michel, H; Miller, R | 1 |
| Kobayashi, K; Kuroda, Y; Saito, M | 1 |
| Gear, AR; Schneider, W | 1 |
| Nachman, RL | 1 |
| Rapaport, E; Zamecnik, PC | 2 |
| Adachi, K; Halprin, KM; Iizuka, H; Levine, V | 1 |
| Shepherd, JT; Vanhoutte, PM; Verhaeghe, RH | 1 |
| Blanquet, S; Fayat, G; Fromant, M | 1 |
| Buckley, JT | 1 |
| Saito, M | 1 |
| Allison, AC; Garcia, RC; Leoni, P | 1 |
| Bleehen, T; Keele, CA | 1 |
| Brown, RD; Kronenberg, H; Rickard, KA; Yuen, E | 1 |
| Lowenstein, JM; Schultz, V | 1 |
| Ueland, PM | 1 |
| Berglund, A; Israelsson, B; Ljungqvist, U; Malmquist, J | 1 |
| Okada, Y; Saito, M | 1 |
| Fredholm, BB; Hjemdahl, P | 1 |
| Fujitani, B; Shimizu, M; Tsuboi, T; Yoshida, K | 1 |
| Giroz, M; Lavoinne, A; Marchand, JC; Matray, F | 1 |
| Greengard, P; Hegstrand, LR; Morgenroth, VH; Roth, RH | 1 |
| Howell, SL; Montague, W | 1 |
| Goto, M; Tsuda, Y; Yatani, A | 1 |
| Agarwal, KC; Parks, RE; Townsend, LB | 1 |
| Sweeney, K; Young, RJ | 1 |
| Reibel, DK; Rovetto, MJ | 1 |
| Cooper, DR; Lewis, GP; Lieberman, GE; Webb, H; Westwick, J | 1 |
| Berne, RM; Rubio, R; Winn, HR | 1 |
| Matsumoto, SS; Raivio, KO; Seegmiller, JE | 1 |
| Aberer, W; Huber, E; Stitzel, R; Winkler, H | 1 |
| Gordon, JL; Pearson, JD | 2 |
| Ku, CS; Wu, KK | 1 |
| Gangarosa, LP; Hubbard, WC; Hung, CT; Park, NH | 1 |
| Bodevin, E; Caen, JP; Dosne, AM; Escoubet, B | 1 |
| Cusack, NJ; Planker, M | 1 |
| Maguire, MH; Satchell, DG | 1 |
| Nunn, B | 1 |
| Jenkins, CS; Oosterhuis, H; Prenger, D; ten Cate, JW; Vos, J | 1 |
| Kuchibhotla, J; Subbarao, K | 1 |
| Hughes, RD; Langley, PG; Silk, DB; Ton, HY; Williams, R | 1 |
| Bauvois, B; Bodevin, E; Caen, JP; Dosne, AM; Legrand, C | 1 |
| Jinbo, C | 1 |
| Robinson, RL; Stevens, P; Stitxel, R; Van Dyke, K | 1 |
| Jaisson, F; Letohic, F; Prost-Dvojaković, RJ; Vainer, H | 1 |
| Bär, HP; Frew, R; McKenzie, SG | 1 |
| Bourret, LA; Cutler, LS; Rodan, GA | 1 |
| Drummond, AH; Gordon, JL; Grainge, CA; MacIntyre, DE | 1 |
| Niewiarowski, S; Rucinski, B; Subbarao, K | 1 |
| Cook, MA; Hamilton, JT; Okwasaba, FK | 1 |
| De Jong, JW; Stam, H | 1 |
| Colman, RF; Pal, PK; Wyatt, JL | 1 |
| Baue, AE; Chaudry, IH; Sayeed, MM | 2 |
| Spedding, M; Weetman, DF | 1 |
| Dean, BM; Perrett, D | 1 |
| Michaeli, D; Orloff, KG | 1 |
| Collier, JR | 1 |
| Lebedeva, AI; Makarov, AD; Opanasenko, VK | 1 |
| Bär, HP; Frew, R; Hutchison, KJ; McKenzie, SG | 1 |
| Evans, FE; Sarma, RH | 2 |
| Ts'ao, C | 1 |
| Jones, CE; Parker, JC; Thomas, JX | 1 |
| Makarov, AD; Mal'ian, AN; Sarancha, IuP | 1 |
| Arfors, KE; Bergqvist, D | 1 |
| Butler, CF; O'Callaghan, J; Rehm, WS; Sanders, SS | 1 |
| Manandhar, MS; Van Dyke, K | 1 |
| Cory, JG; Mansell, MM | 1 |
| Fisher, HF; Stickel, DC; Subramanian, S | 1 |
| Sjöberg, B; WAHLSTRöm, BA | 1 |
| Mel'gunov, VI | 1 |
| Born, GV; Feinberg, H | 1 |
| Onajobi, FD | 1 |
| Hamilton, JT; Okwuasaba, FK | 1 |
| Berne, RM; Mentzer, RM; Rubio, R | 1 |
| Agarwal, KC; Parks, RE | 2 |
| Cornell, NW; Krebs, HA; Lund, P | 1 |
| Busto, R; Nilsson, L | 1 |
| Baumgartner, H; Gibb, JW; Peer, LJ; Snider, SR; Winkler, H | 1 |
| Buhl, MR | 1 |
| Chagoya de Sánchez, V; Díaz-Muñoz, M; Hernández-Muñoz, R | 1 |
| David, M; Griesmacher, A; Horvath, G; Mueller, MM; Weigel, G | 1 |
| Meghji, P; Pearson, JD; Slakey, LL | 2 |
| Furman, MI; Goldschmidt-Clermont, PJ; Nachmias, VT; Pollard, TD; Safer, D; Wachsstock, D | 1 |
| De Croos, PZ; Johnson, ME; Kar, L; Matsumura, P; Roman, SJ | 1 |
| Downes, CP; Vaziri, C | 1 |
| Matsuda, T; Mori, M; Tsushima, H | 1 |
| Colman, RF; Colman, RW; Figures, WR; Scearce, LM | 1 |
| Karaulov, AV; Melkova, OM; Porodenko, NV; Prokudin, VIu | 1 |
| Späth, L; Starke, K; von Kügelgen, I | 1 |
| Aursnes, I; Stenberg-Nilsen, H | 1 |
| Ekholm, J; Hanahan, DJ; Nouchi, T; Tatsumi, Y | 1 |
| Decout, JL; Fontecave, M; Lepoivre, M; Lhomme, J; Roy, B | 1 |
| Colman, RF; Colman, RW; Freedman, MD; Grana, G; Hu, CJ; Mills, DC; Minniti, C; Puri, R | 1 |
| Burgmann, H; Reckendorfer, H; Sperlich, M; Spieckermann, PG | 2 |
| Davis, CW; Dowell, ML; Lethem, M; Van Scott, M | 1 |
| Fujise, H; Higashijima, M; Hisamatsu, S; Ogawa, E; Sakamoto, Y; Sonoki, S; Takahashi, R | 1 |
| Berne, RM; Headrick, JP; Matherne, GP | 1 |
| King, CR; Maguire, MH; Slegel, P; Szabo, I | 1 |
| Flameng, W; Möllhoff, T; Sukehiro, S; Van Aken, H; Van Belle, H | 1 |
| Gobran, LI; Griese, M; Rooney, SA | 1 |
| Cunha, RA; Sebastião, AM | 1 |
| Hjemdahl, P; Larsson, PT; Söderbäck, U; Sollevi, A; Wallen, NH | 1 |
| Keen, M; Kelly, E; MacDermot, J; Nobbs, P | 1 |
| Alexander, B; Mathie, RT | 1 |
| Akasawa, A; Ebisawa, M; Iikura, Y; Matsumoto, K; Saito, H; Sakaguchi, N | 1 |
| Borst, MM; Schrader, J | 1 |
| Kawamura, M; Kondo, T; Matsui, T; Nakamichi, N; Niitsu, A; Ohno, Y | 1 |
| Lachno, R; Mankad, P; Yacoub, M | 1 |
| Gerber, G; Grune, T; Schneider, C; Schneider, W; Siems, WG | 1 |
| Lieberman, M; Wagenknecht, B | 1 |
| Cahill, BE; Haile, DM; Kadowitz, PJ; Neely, CF | 1 |
| Himmelreich, G; Riess, H | 2 |
| Colman, RW; Puri, RN | 2 |
| Flameng, W; Hendrickx, M; Möllhoff, T; Sukehiro, S; Van Belle, H | 1 |
| Heppel, LA; Huang, NN; Wang, DJ | 1 |
| Adamo, EB; Mulè, F; Postorino, A; Serio, R | 1 |
| Berne, RM; Berr, SS; Han, DC; Headrick, JP; Matherne, GP | 1 |
| Chen, G; Suzuki, H | 1 |
| Armstrong, ML; Brotherton, AF; Heistad, DD; Lopez, JA; Piegors, DJ | 1 |
| Graham, HC; Williams, RJ | 1 |
| Kinzer, D; Lehmann, V | 1 |
| Cadnapaphornchai, P; Golembieski, A; Kellner, D; McDonald, FD | 1 |
| Iwamoto, K; Lin, ML; Seno, M | 1 |
| Aksnes, G; Ilebekk, A; Kirkeböen, KA | 1 |
| Gilboe, DP | 1 |
| Carabaza, A; Ciudad, CJ; Guinovart, JJ; Mor, A; Ricart, MD | 1 |
| Allison, WS; Verburg, JG | 1 |
| Bru-Capdeville, AC; Najar, HM; Peters, JH; Ruhl, S | 1 |
| Fujimori, H; Hibi, K; Sasaki, T; Senda, M; Yoshioka, M | 1 |
| Collin, T; Fournier, F; Guilbault, P; Honoré, E | 1 |
| Kather, H | 1 |
| Andreoli, SP; Liechty, EA; Mallett, C | 1 |
| Bjur, RA; Sedaa, KO; Shinozuka, K; Westfall, DP | 1 |
| Belardinelli, L; Boykin, MT; Hill, JA; Shryock, JC | 1 |
| Allen, TG; Burnstock, G | 1 |
| Hope, W; Rose'Meyer, RB | 1 |
| Holgate, ST; Mann, JS; Renwick, AG | 1 |
| Keery, RJ; Lumley, P | 1 |
| McGarrity, ST; Stephenson, AH; Webster, RO | 1 |
| Deussen, A; Möser, GH; Schrader, J | 1 |
| Bradford, H; Colman, RF; Colman, RW; Hu, CJ; Puri, RN; Zhou, FX | 1 |
| de Groat, WD; Theobald, RJ | 1 |
| Dunwiddie, TV; Fredholm, BB; Proctor, W; Van der Ploeg, I | 1 |
| Chin, WP; Imai, S; Jin, H; Nakazawa, M | 1 |
| Kobayashi, S; Kurosawa, M; Okayama, Y | 1 |
| Su, C | 1 |
| Jennings, RB; Steenbergen, C | 1 |
| Opie, LH; Owen, P; Reichart, B; Schubert, T; Vetter, H | 1 |
| Iwane, H; Izawa, T; Komabayashi, T; Shinoda, S; Suda, K; Tsuboi, M | 1 |
| Ainz, LF; Gandarias, JM; Gil-Rodrigo, CE; Gómez, R; Malillos, M; Requejo, D | 1 |
| Blum, JJ; Darling, TN | 1 |
| Bürrig, KF; Kelm, MK; Kroll, K; Schrader, J | 1 |
| de la Harpe, J; Nathan, CF | 1 |
| Grantham, CJ; Jackowski, JT; Ryan, US; Wanner, A | 1 |
| Dickinson, ES; Gordon, EL; Moreau, D; Pearson, JD; Slakey, LL | 1 |
| Hertz, L; Matz, H | 1 |
| Abu-Zeid, MM; Fujimori, H; Fuke, A; Goto, A; Hirai, K; Ishii, M; Parvez, H; Sugimoto, T; Yamada, K; Yoshioka, M | 1 |
| Cantley, L; Kaplan, D; Roberts, T; Whitman, M | 1 |
| Gonçalves, ML; Ribeiro, JA | 1 |
| Cunningham, TW; Johnson, KJ; McCulloch, KK; Ward, PA | 1 |
| Fox, IH; Tekkanat, KK | 1 |
| Bhaumik, D; Datta, AK | 1 |
| Belzer, I; Friedberg, I; Huang, NN; Lane, E; Lustig, KD; Weisman, GA | 1 |
| Berne, RM; Meghji, P; Rubio, R | 1 |
| Forster, E; Neary, JT; Norenberg, LO; Norenberg, MD; van Breemen, C | 1 |
| King, MM; Kwiatkowski, AP; Shell, DJ | 1 |
| Fraser, LR; Monks, NJ | 1 |
| Allison, WS; Brown, EL; Bullough, DA; Saario, JD | 1 |
| Bowditch, J; Brown, AK; Dow, JW; Nigdikar, S | 1 |
| Rovetto, MJ | 1 |
| Ross, SM; Sabri, MI; Spencer, PS | 1 |
| Colman, RF; Colman, RW; Figures, WR; Mills, DC; Scearce, LM; Stewart, GJ | 1 |
| Fredholm, BB; Li, YO | 1 |
| Maggi, CA; Manzini, S; Meli, A | 1 |
| Lohse, MJ; Schwabe, U; Ukena, D | 1 |
| Husted, SE; Nedergaard, OA | 1 |
| Fernandez, B; Galdiz, B; Gandarias, JM; Santa Maria, S | 1 |
| Chen, J; Colman, RF; Colman, RW; Figures, WR; Scearce, LM; Wachtfogel, Y | 1 |
| Colman, RW | 1 |
| Bukoski, RD; Sparks, HV | 1 |
| Aramaki, Y; Inaba, A; Takahashi, M; Tsuchiya, S | 1 |
| Fox, IH; Hurley, MC; Lin, B | 1 |
| Mela-Riker, LM; pukoski, RD; Sparks, HV | 1 |
| Gordon, EL; Pearson, JD; Slakey, LL | 1 |
| Cartner, LA; Holliss, DG; Humphrey, SM | 1 |
| Bushfield, M; MacIntyre, DE; MacMillan, LJ; McNicol, A; Moffat, KJ; Murdoch, FA; Rossi, AG; Thomson, A | 1 |
| Kowalska, MA; Rao, AK | 1 |
| Chen, J; Colman, RF; Colman, RW; Daniel, J; DeFeo, P; Figures, WR; Scearce, LM; Stewart, G; Zhou, F | 1 |
| Alborch, E; Campos, V; Miranda, FJ; Salom, JB; Terrasa, JC; Torregrosa, G | 1 |
| Beck, K; Calamai, F; Staderini, G; Susini, T | 1 |
| Barankiewicz, J; Cohen, A; Dosch, HM | 1 |
| Klenow, H; Ostergaard, E | 1 |
| Lasley, R; Mainwaring, R; Mentzer, RM; Rubio, R; Wyatt, DA | 1 |
| Chung, SY; Colman, RF; Colman, RW; Figures, WR; Morinelli, TA; Niewiarowski, S; Tuszynski, GP; Wu, QX | 2 |
| Basuyau, JP; Chedeville, A; Claeyssens, S; Hamet, M; Lavoinne, A | 1 |
| Imago, M; Miyake, K; Takeo, S; Tanonaka, K | 1 |
| Buc, HA; Garreau, F; Hamet, M; Moncion, A; Pérignon, JL; Thuillier, L | 1 |
| Andraghetti, G; Cordera, R; Gherzi, R; Versari, G | 1 |
| Cushley, MJ; Holgate, ST; Mann, JS; Renwick, AG | 1 |
| Edlund, A; Sidén, A; Sollevi, A | 1 |
| Lindgren, CA; Smith, DO | 1 |
| Andersson, P; Butcher, S; Hagberg, H; Jacobson, I; Lacarewicz, J; Sandberg, M | 1 |
| Dmitrienko, NP; Goroshnikova, TV | 1 |
| Carr, WE; Gleeson, RA; Trapido-Rosenthal, HG | 1 |
| Barbenel, JC; Forbes, CD; Lowe, GD; Saniabadi, AR | 1 |
| Dillon, PF; He, MX; Romig, GD; Sparks, HV; Wangler, RD | 1 |
| Arnout, J; Deckmyn, H; Gresele, P; Vermylen, J | 1 |
| Colman, RW; Figures, WR; Rao, AK; Scearce, LM; Strimpler, AM; Zhou, FX | 1 |
| Satchell, D | 1 |
| Baue, AE; Chaudry, IH; Hull, MJ; Sumpio, BE | 1 |
| Hassinen, IE; Kiviluoma, KT; Peuhkurinen, KJ | 1 |
| Ehinger, BE; Fredholm, BB; Lindström, K; Perez, MT | 1 |
| Fuchs, BD; Gorman, MW; Sparks, HV | 1 |
| Dmitrenko, NP; Goroshnikova, TV | 1 |
| Holmsen, H | 2 |
| Henderson, JF; Paterson, AR; Young, JD | 1 |
| Ainz, LF; Gandarias, JM; Gil-Rodrigo, CE; Goiriena, JJ; Gómez, R; Martínez, I | 1 |
| Alderson, T | 1 |
| Hernandez, J; Laorden, ML; Ribeiro, JA | 1 |
| Suzuki, H | 1 |
| Baines, AD; Ramos-Salazar, A | 1 |
| Teuscher, E; Weidlich, V | 1 |
| Boston, GD; Paton, DM; Webster, DR | 1 |
| Belloni, FL; Elkin, PL; Giannotto, B | 1 |
| Kartha, S; Toback, FG | 1 |
| Quintana, J | 1 |
| Mawhinney, MG; Milam, DF; Smith, CG; Thomas, JA | 1 |
| Weiss, HJ | 2 |
| Fisher, HF | 1 |
| Moore, MM; Perkins, JP | 1 |
| Fujioka, M; Nakatani, Y | 1 |
| Bartlet, AL | 1 |
| Holmsen, H; Sixma, JJ; Trieschnigg, AC | 1 |
| Grant, RA; Zucker, MB | 1 |
| Brand, H; Rogers, J; Weiss, HJ | 1 |
| Kubiaz, P; Suranová, J | 1 |
| Ingerman, C; Kocsis, JJ; Silver, MJ; Smith, JB | 1 |
| Braude, AI; Davis, CE; Robbins, RS; Weller, RD | 1 |
| Makarewicz, W; Stankiewicz, A | 1 |
| Caen, J; Janneau, C; Lukasiewicz, H; Vainer, H | 1 |
| Kikugawa, K | 1 |
| Kattlove, HE | 1 |
| Jyssum, S | 1 |
| Holmsen, H; Rozenberg, MC | 1 |
| Nishino, T | 1 |
| Greiling, H; Kisters, R; Momburg, M; Stuhlsatz, HW | 1 |
| De Gaetano, G; Donati, MB; Vermylen, J | 1 |
| Berne, RM; Rubio, R | 1 |
| Aznar, J; Vallés, J | 1 |
| Francis, SH; Meriwether, BP; Park, JH | 2 |
| Barrnett, RJ; Beer, M; Gibson, DW | 1 |
| Del Monte, M; Nadler, HL; Rao, GJ | 1 |
| Rall, TW | 1 |
| Askari, A; Rao, SN | 1 |
| Garrity, M; Morley, A; Quesenberry, P; Stohlman, F | 1 |
| Ardlie, NG; Kinlough-Rathbone, RL; McElroy, FA; Mustard, JF; Packham, MA | 1 |
| Field, JB; Yamashita, K | 1 |
| Anderson, BM; Yuan, JH | 2 |
| Hiratsuka, T; Tanaka, K; Uchida, K | 1 |
| Inamasu, M; Iwai, H; Takeyama, S | 1 |
| Danenberg, PV; Montgomery, KA; Santi, DV | 1 |
| Marx, W; Shoyab, M | 1 |
| Cortellaro, M | 1 |
| Fujimoto, S; Uehara, K | 1 |
| Asryants, RA; Ivanov, MV; Nagradova, NK | 1 |
| Barrio, JR; Leonard, NJ; Secrist, JA; Weber, G | 1 |
| Wimmer, E | 1 |
| Friedberg, NM; Zucker, MB | 1 |
| Hansen, O | 1 |
| Kensler, PC; Levine, L; Salzman, EW | 1 |
| Rozenberg, MC; Walker, CM | 1 |
| Tomita, T; Watanabe, H | 1 |
| Meinertz, T; Nawrath, H; Scholz, H | 1 |
| Salzman, EW; Weisenberger, H | 1 |
| Rall, TW; Sattin, A | 1 |
| Kinlough-Rathbone, RL; Mustard, JF; Packham, MA; Reimers, HJ | 1 |
| Hirschhorn, R; Weissmann, G | 1 |
| Suzuki, I; Wold, WS | 1 |
| Adams, MJ; Chandrasekhar, K; McPherson, A; Rossmann, MG | 1 |
| Fynn, GH; Seddon, B | 1 |
| Beckner, SK; Gourley, DR | 1 |
| Gentry, MK; Olsson, RA; Townsend, RS | 1 |
| Feldman, JM; Jackson, TB | 1 |
| Edwards, AM; Elliott, WH | 1 |
| Haslam, RJ | 1 |
| Markwardt, F | 1 |
| Kuchii, M; Miyahara, JT; Shibata, S | 1 |
| Estensen, RD; Rao, GH; White, JG | 1 |
| Dietrich, LS; Siebert, G | 1 |
| Douglas, JR; Minkes, MS; Needleman, P | 1 |
| Deykin, D; Hardisty, RM; Howard, MA; Hutton, RA | 1 |
| Barthel, W; Glusa, E; Markwardt, F | 1 |
| Anderson, BM; Fisher, TL; Vercellotti, SV | 1 |
| Clark, RB; Gross, R; Perkins, JP; Su, YF | 1 |
| Konijn, TM; Moens, PB | 1 |
| Cazenave, JP; Guccione, MA; Mustard, JF; Packham, MA | 1 |
| Chopra, DP; Flaxman, BA; Harper, RA | 1 |
| Hossmann, KA; Kleihues, P; Kobayashi, K | 1 |
| Daly, JW; Huang, M | 1 |
| Defendi, V; Hirai, K; Roller, BA | 1 |
| Tao, M; Yuh, KC | 1 |
| Iso, T | 1 |
| Chokshi, DS; Walkenhorst, WG; Winer, N | 1 |
| Forsee, WT; Kahn, JS | 1 |
| Barrett, J; Beis, I | 1 |
| Krzyzanowska, M; Niemierko, W | 1 |
| Heyns, AP; Potgieter, GM; Retief, FP; van den Berg, DJ | 1 |
| Arfors, KE; Matheson, NA; McKenzie, FN | 1 |
| Frantsuzova, SB | 1 |
| Aoki, M; Nakajima, K; Satoh, F; Shirai, K; Takimoto, M | 1 |
| Bellanger, R; Caen, JP; Jenkins, CS; Michel, H | 1 |
| Booyse, FM; Rafelson, ME | 1 |
| Duncan, HJ; Rees, WR | 1 |
| Green, D; Rossi, EC | 1 |
| Henderson, JF; Snyder, FF | 1 |
| Brown, PR; Parks, RE | 1 |
| Cory, JG; Mansell, MM; Russell, FA | 1 |
| Cohen, PJ | 1 |
| Hardisty, RM | 1 |
| Mester, L; Mester, M | 1 |
| Caen, J; Rendu, F; Rodriguez-Zeballos, A | 1 |
| Bartmann, P; Hanke, T; Holler, E; Kosakowski, HM | 1 |
| Donner, L; Housková, J | 1 |
| Eika, C | 1 |
| Higashi, O; Kikuchi, Y; Konno, K | 1 |
| Born, GV; Foulks, J; Michal, F; Sharp, DE | 1 |
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| Jalkanen, S; Kaarniranta, K; Kauppinen, A; Korhonen, AM; Lehti, K; Losenkova, K; Loukovaara, S; Müller, CE; Yegutkin, GG; Zeiner, J; Zuccarini, M | 1 |
| Agostinho, P; Andrade, GM; Canas, PM; Carmo, M; Cunha, RA; Duarte, FV; Fernandes, FD; Gonçalves, FQ; Oses, JP; Palmeira, CM; Tomé, AR | 1 |
| Bertoldo, MJ; Bustamante, S; Gilchrist, RB; Kanakkaparambil, R; Lavea, CF; Richani, D; Riepsamen, AH | 1 |
| Huang, L; Lilley, DMJ; Wang, J | 1 |
| Boison, D; Jalkanen, S; Karikoski, M; Laurila, J; Losenkova, K; Yegutkin, GG; Zuccarini, M | 1 |
| Cheng, D; Gillespie, DG; Jackson, EK; Menshikova, EV; Mi, Z | 1 |
| Battastini, AMO; Bertoni, APS; Braganhol, E; de Campos, RP; Stefani, GP; Tamajusuku, ASK; Wink, MR | 1 |
| Chlubek, D; Dziedziejko, V; Kłos, P; Puchałowicz, K; Tarnowski, M; Tkacz, M | 1 |
| Bai, X; Liu, P; Zhou, L; Zhu, L | 1 |
| Baile, MG; Claypool, SM; Kandasamy, S; Lu, Y; Ogunbona, OB; Senoo, N | 1 |
| Chen, J; Li, X; Lv, Q; Wang, Z; Wu, H; Xue, Y | 1 |
| Da Silva, RS; Lutte, AH; Majolo, JH | 1 |
| Arya, G; Dill, E; Jardine, PJ; Kelch, BA; Morais, MC; Pajak, J; Reyes-Aldrete, E; White, MA | 1 |
| Bliden, KP; Dahlen, J; Fisher, R; Gurbel, PA; Speros, PC; Sukavaneshvar, S; Tantry, US | 1 |
| Altié, A; Brouilly, N; Carminita, E; Crescence, L; Dubois, C; Panicot-Dubois, L | 1 |
| Alves, VS; Coutinho-Silva, R; Leite-Aguiar, R; Savio, LEB; Wyse, ATS | 1 |
| Chun, BJ; Kekenes-Huskey, PM; Pace, T; Rahmaninejad, H | 1 |
| Junger, WG; Ledderose, C; Valsami, EA | 1 |
| Alvez, FL; Bona, NP; da Silva Dos Santos, F; de Farias, AS; de Moraes Meine, B; Luduvico, KP; Pedra, NS; Soares, MSP; Spanevello, RM; Spohr, L; Stefanello, FM | 1 |
| Friebel, J; Hassanein, A; Jakobs, K; Landmesser, U; Puccini, M; Rauch, C; Rauch, U | 1 |
| Han, X; He, M; Kong, Y; Li, Y; Liu, G; Ren, J; Shi, J; Yan, W; Zhang, Y; Zhao, Z | 1 |
| Baranyi, M; Bitter, I; Demeter, K; Kristóf, Z; Mut-Arbona, P; Sperlágh, B; Tod, P | 1 |
| Antoniadis, AP; Bakogiannis, C; Ballauri, I; Bougiouklis, D; Fragakis, N; Gerou, S; Giannopoulos, G; Gika, HG; Karamitsos, TD; Lazaridis, C; Papadopoulos, CE; Sotiriadou, M; Theodoridis, GA; Vassilikos, V; Vergopoulos, S; Virgiliou, C | 1 |
| Frontera, T; González Sanabria, J; Hurtado Paso, M; Losavio, A | 1 |
| Grewal, AK; Kaur, P; Khan, H; Singh, TG; Sood, S | 1 |
| Angiolillo, DJ; Been, L; Franchi, F; Galli, M; Rollini, F; Zenni, MM | 1 |
| Guyot, F; Moeller, C; Schmidt, C; Wilke, M | 1 |
| Chen, Z; Gu, G; Jia, W; Li, M; Liu, L; Weng, H; Xiao, M; Zhou, H; Zhou, Y | 1 |
| Beer-Hammer, S; Eggstein, C; Granja, TF; Köhler, D; Leiss, V; Nürnberg, B; Rosenberger, P | 1 |
| Andrejew, R; Aoki, V; Battastini, AM; Benard, G; Custódio, RWA; de Brito, CA; Duarte, AJDS; Figueiró, F; Glaser, T; Goffinet, C; Kazmierski, J; Oliveira, LM; Pietrobon, AJ; Sato, MN; Scholl, JN; Teixeira, FME; Turdo, AC; Ulrich, H; Yendo, T | 1 |
| Han, K; Huang, X; Ma, M; Sun, T; Yang, S; Zhao, Z; Zhou, Y | 1 |
| Basu, A; Han, D; Krebs, L; Musheev, MU; Niehrs, C; Scholz, C; Schomacher, L | 1 |
| Bender, L; Dorn, C; Franko, M; Franz, C; May, R; Minkenberg, J; Nikoubashman, O; Ridwan, H; Sichtermann, T; Stockero, A; Wiesmann, M | 1 |
| Cheung, SS; Hellsten, Y; Lundberg Slingsby, MH; Nørregaard, LB; Wickham, KA | 1 |
| Cheng, XD; Li, YJ; Wang, JH; Wang, L; Yang, B; Yang, X; Yu, NW; Zhang, J; Zhang, Q; Zhang, X | 1 |
| Azambuja, JH; Begnini, K; Bertoni, APS; Braganhol, E; da Cruz, LLP; da Silveira, F; de Souza, PO; Gelsleichter, NE; Haas, CB; Hasko, G; Leite, RO; Mohr, KR; Prá, MD; Soares, MS; Spanevello, RM; Wink, MR | 1 |
| Gonçalves, J; Queiroz, G; Quintas, C | 1 |
| Amaradasa, K; Bancroft, S; Dimofte, T; Hindle, MS; Hutchinson, JL; Johnson, T; Keith, M; Khalil, J; Mundell, SJ; Naseem, K; Roberts, T | 1 |
| Mayer, RJ; Moran, J; Pinna, S; Werner, E | 1 |
37 review(s) available for adenosine diphosphate and adenosine
| Article | Year |
|---|---|
[Release reaction and adenine nucleotide metabolism of blood platelets].
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Blood Platelets; Calcium; Collagen; Endotoxins; Epinephrine; Humans; Methods; Platelet Aggregation; Serotonin; Spectrophotometry; Thrombin | 1976 |
Extracellular functions of nucleotides in heart and blood vessels.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood Vessels; Calcium; Cell Membrane Permeability; Endothelium; Humans; Ion Channels; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Contraction; Myocardium; Neurotransmitter Agents; Platelet Aggregation; Receptors, Cell Surface; Receptors, Purinergic; Synaptic Transmission | 1985 |
Nucleotide metabolism and cellular damage in myocardial ischemia.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Cell Survival; Coronary Disease; Energy Metabolism; Humans; Hypoxanthine; Hypoxanthines; Inosine; Ion Channels; Myocardial Contraction; Myocardium; Oxygen | 1985 |
Myocardial nucleotide transport.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Biological Transport, Active; Cell Membrane Permeability; Cyclic AMP; Humans; Myocardium; Nucleosides; Phosphorylation | 1985 |
Nucleotide metabolism by endothelium.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Biological Transport; Cell Membrane Permeability; Cells, Cultured; Cyclic AMP; Endothelium; Humans; Kinetics; Nucleosides | 1985 |
Platelet activation: role of an ADP receptor.
Topics: Adenosine; Adenosine Diphosphate; Binding Sites; Blood Platelets; Cell Membrane; Collagen; Cytoplasmic Granules; Fibrinogen; Humans; Models, Theoretical; Molecular Weight; Peptide Hydrolases; Platelet Aggregation; Prostaglandin Endoperoxides; Receptors, Cell Surface; Receptors, Purinergic | 1986 |
Receptors and receptor mechanisms of endogenous platelet stimulatory and inhibitory mediators.
Topics: Adenosine; Adenosine Diphosphate; Blood Platelets; Epinephrine; Epoprostenol; Humans; Platelet Activating Factor; Platelet Aggregation; Prostaglandin D2; Prostaglandins D; Receptors, Cell Surface; Serotonin; Structure-Activity Relationship; Thrombin; Thromboxane A2; Vasopressins | 1986 |
Nucleotide metabolism of platelets.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Biological Transport, Active; Blood Platelets; Calcium; Cytoplasmic Granules; Humans; Serotonin | 1985 |
Formaldehyde-induced mutagenesis: a novel mechanism for its action.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Animals; Cell Transformation, Neoplastic; Cricetinae; Dinucleoside Phosphates; DNA Repair; Drosophila melanogaster; Drug Resistance; Female; Formaldehyde; Larva; Male; Mammals; Mesocricetus; Mice; Mutation; Oogenesis; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Spermatogenesis; Stress, Physiological | 1985 |
The pharmacology of platelet inhibition.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Anti-Inflammatory Agents; Anticoagulants; Aspirin; Blood Platelets; Citric Acid Cycle; Collagen; Cyclic AMP; Dipyridamole; Hexosephosphates; Histamine H1 Antagonists; Microscopy, Electron; Platelet Adhesiveness; Prostaglandins; Serotonin; Xanthines | 1972 |
Glutamate dehydrogenase--ligand complexes and their relationship to the mechanism of the reaction.
Topics: Adenosine; Adenosine Diphosphate; Binding Sites; Glutamate Dehydrogenase; Glutamates; Glutarates; Guanosine Triphosphate; Ketoglutaric Acids; Kinetics; Leucine; Ligands; Mathematics; Models, Biological; Models, Structural; NAD; NADP; Oxidation-Reduction; Protein Binding; Pyridines; Spectrophotometry; Spectrophotometry, Ultraviolet; Time Factors | 1973 |
Adenine nucleotide metabolism in the heart.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Carbon Radioisotopes; Cardiomegaly; Coronary Vessels; Deamination; Diffusion; Dogs; Erythrocytes; Guinea Pigs; Hypoxanthines; Hypoxia; Inosine; Inosine Nucleotides; Ischemia; Kidney; Liver; Myocardium; Nucleosides; Nucleotidases; Perfusion; Purines; Rabbits; Rats | 1974 |
Role of cyclic AMP in platelet function.
Topics: Adenosine; Adenosine Diphosphate; Aspirin; Biological Transport; Blood Platelets; Butyrates; Carbon Isotopes; Cell Aggregation; Collagen; Cyclic AMP; Epinephrine; Kaolin; Kinetics; Models, Biological; Phentolamine; Platelet Adhesiveness; Propranolol; Protein Kinases; Time Factors; Tritium | 1972 |
The metabolic function of oxygen and biochemical lesions of hypoxia.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Anaerobiosis; Animals; Brain; Carbon Dioxide; Citric Acid Cycle; Glycolysis; Humans; Hydrogen-Ion Concentration; Hydrolysis; Hypothermia, Induced; Hypoxia; Lactates; Mitochondria; Oxidative Phosphorylation; Oxygen Consumption; Respiration | 1972 |
Haemostatic functions of platelets and their disorders.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Afibrinogenemia; Aspirin; Blood Coagulation Disorders; Blood Platelet Disorders; Blood Platelets; Carbon Isotopes; Hemostasis; Humans; Microscopy, Electron; Phosphates; Phosphorus Isotopes; Platelet Adhesiveness | 1972 |
Purinergic receptors in the heart.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adrenergic Fibers; Animals; Cholinergic Fibers; Coronary Vessels; Cyclic AMP; Guinea Pigs; Heart Atria; Heart Rate; Muscle, Smooth; Muscles; Myocardium; Neuroeffector Junction; Purine Nucleosides; Purine Nucleotides; Purines; Rabbits; Receptors, Drug | 1980 |
[Biochemical mechanism of the radioprotective action of adenylic compounds].
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; beta-Aminoethyl Isothiourea; Chromosome Aberrations; Cyclic AMP; Deoxyribonucleoproteins; DNA; Dose-Response Relationship, Drug; Drug Combinations; Humans; Radiation Injuries, Experimental; Radiation-Protective Agents; Species Specificity | 1982 |
Characteristics of an ADP receptor mediating platelet activation.
Topics: Adenosine; Adenosine Diphosphate; Adenylyl Cyclases; Binding Sites; Blood Platelets; Cell Membrane; Fibrinogen; Receptors, Cell Surface; Receptors, Purinergic | 1984 |
Interactive regulation of the ATP-sensitive potassium channel of cardiac muscle.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Drug Interactions; Guanosine Triphosphate; Myocardium; Neurotransmitter Agents; Potassium Channels; Radioligand Assay; Sulfonylurea Compounds; Uridine Triphosphate | 1994 |
The medicinal chemistry of the P2 receptor family.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Arteriosclerosis; Cloning, Molecular; Clopidogrel; Cystic Fibrosis; Humans; Ophthalmic Solutions; Polyphosphates; Receptors, Purinergic P2; Structure-Activity Relationship; Ticlopidine; Tissue Distribution; Uracil Nucleotides | 2001 |
Purinergic signaling and vascular cell proliferation and death.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apoptosis; Cell Division; Endothelium, Vascular; Humans; MAP Kinase Signaling System; Muscle, Smooth, Vascular; Receptors, Purinergic P1; Receptors, Purinergic P2; Uridine Triphosphate; Vascular Diseases | 2002 |
Preclinical and clinical studies with selective reversible direct P2Y12 antagonists.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Administration, Oral; Animals; Arterial Occlusive Diseases; Clinical Trials as Topic; Dogs; Double-Blind Method; Drug Evaluation, Preclinical; Female; Fibrinolytic Agents; Humans; Injections, Intravenous; Male; Membrane Proteins; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Pyridines; Rabbits; Randomized Controlled Trials as Topic; Receptors, Purinergic P2Y12; Thrombosis; Ticagrelor | 2005 |
Purinergic regulation of glomerular microvasculature and tubular function.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Electrolytes; Glomerular Filtration Rate; Homeostasis; Humans; Kidney Glomerulus; Kidney Tubules; Microcirculation; Receptors, Purinergic | 2008 |
Unmet needs in oral antiplatelet therapy with ADP receptor blocking agents.
Topics: Acute Coronary Syndrome; Adenosine; Adenosine Diphosphate; Administration, Oral; Clinical Trials as Topic; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y12; Ticagrelor; Ticlopidine | 2009 |
Ticagrelor: the first reversibly binding oral P2Y12 receptor antagonist.
Topics: Acute Coronary Syndrome; Adenosine; Adenosine Diphosphate; Animals; Atherosclerosis; Clinical Trials as Topic; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y12; Ticagrelor; Ticlopidine; Vasoconstriction | 2009 |
Purines and sensory nerves.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Central Nervous System; Ganglia, Sensory; Humans; Mechanotransduction, Cellular; Neural Pathways; Pain; Purines; Receptors, Purinergic; Receptors, Purinergic P1; Receptors, Purinergic P2; Sensation Disorders; Sensory Receptor Cells; Viscera | 2009 |
Update on antiplatelet therapy in acute coronary syndromes: what do new drugs bring into clinical practice?
Topics: Acute Coronary Syndrome; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Clopidogrel; Humans; Lactones; Piperazines; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Prasugrel Hydrochloride; Pyridines; Thiophenes; Ticagrelor; Ticlopidine | 2009 |
Differential regulation of microglial motility by ATP/ADP and adenosine.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Brain Injuries; Cell Movement; Humans; Microglia; Receptor, Adenosine A2A; Up-Regulation | 2009 |
The platelet P2Y₁₂ receptor for adenosine diphosphate: congenital and drug-induced defects.
Topics: Adenosine; Adenosine Diphosphate; Animals; Blood Platelet Disorders; Blood Platelets; Clopidogrel; Female; Hemorrhage; Humans; Male; Mice; Mutation; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Signal Transduction; Thiophenes; Ticagrelor; Ticlopidine | 2011 |
Ticagrelor: from discovery to Phase III clinical trial.
Topics: Acute Coronary Syndrome; Adenosine; Adenosine Diphosphate; Clinical Trials, Phase III as Topic; Clopidogrel; Coronary Artery Disease; Humans; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Ticagrelor; Ticlopidine | 2010 |
Bleeding manifestations of congenital and drug-induced defects of the platelet P2Y12 receptor for adenosine diphosphate.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Clinical Trials, Phase III as Topic; Clopidogrel; Hemorrhage; Humans; Piperazines; Platelet Activation; Prasugrel Hydrochloride; Quinazolinones; Receptors, Purinergic P2Y12; Sulfonamides; Thiophenes; Ticagrelor; Ticlopidine | 2011 |
Adenosine and hypoxia-inducible factor signaling in intestinal injury and recovery.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Extracellular Space; Humans; Hypoxia; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Immunity, Mucosal; Inflammation; Intestinal Diseases; Intestinal Mucosa; Irritable Bowel Syndrome; Mice; Nucleotides; Procollagen-Proline Dioxygenase; Receptors, Purinergic P1; Signal Transduction | 2012 |
Purines as potential morphogens during embryonic development.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Animals, Genetically Modified; Embryo, Nonmammalian; Embryonic Development; Female; Gene Expression Regulation, Developmental; Humans; Mice; Models, Biological; Pregnancy; Purines; Receptors, Purinergic; Signal Transduction; Xenopus laevis; Zebrafish | 2012 |
[Nucleotide receptors and the cell motility].
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Brain Neoplasms; Cell Movement; Cell Transformation, Neoplastic; Extracellular Matrix; Granulocytes; Humans; Microglia; Neuroglia; Signal Transduction; Uridine Triphosphate | 2014 |
Purinergic signaling in the modulation of redox biology.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Biology; Oxidation-Reduction | 2021 |
Adenosine as a Key Mediator of Neuronal Survival in Cerebral Ischemic Injury.
Topics: Adenosine; Adenosine Diphosphate; Brain Ischemia; Humans; Ischemia; Receptors, Purinergic P1 | 2022 |
Purinergic signaling: a potential therapeutic target for ischemic stroke.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Antigens, CD; Apyrase; Humans; Ischemic Stroke; Signal Transduction; Thrombosis | 2023 |
10 trial(s) available for adenosine diphosphate and adenosine
| Article | Year |
|---|---|
Clopidogrel inhibits the binding of ADP analogues to the receptor mediating inhibition of platelet adenylate cyclase.
Topics: Adenosine; Adenosine Diphosphate; Adenylyl Cyclase Inhibitors; Adult; Binding Sites; Blood Platelets; Clopidogrel; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Receptors, Purinergic; Thionucleotides; Thrombin; Ticlopidine | 1992 |
Increase in plasma levels of adenosine and adenine nucleotides after intravenous infusion of buflomedil in humans.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aged; Analysis of Variance; Arterial Occlusive Diseases; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Pyrrolidines; Vasodilator Agents | 1995 |
Ticagrelor yields consistent dose-dependent inhibition of ADP-induced platelet aggregation in patients with atherosclerotic disease regardless of genotypic variations in P2RY12, P2RY1, and ITGB3.
Topics: Adenosine; Adenosine Diphosphate; Area Under Curve; Atherosclerosis; Clopidogrel; Dose-Response Relationship, Drug; Humans; Integrin beta3; Pharmacogenetics; Platelet Aggregation; Polymorphism, Single Nucleotide; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Ticagrelor; Ticlopidine | 2009 |
Pretreatment platelet reactivity contribution to residual, post-treatment platelet reactivity in prasugrel-treated and ticagrelor-treated patients.
Topics: Adenosine; Adenosine Diphosphate; Blood Platelets; Humans; Myocardial Infarction; Percutaneous Coronary Intervention; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Predictive Value of Tests; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Thiophenes; Ticagrelor; Time Factors; Treatment Outcome | 2013 |
Comparison of patient intake of ticagrelor, prasugrel, or clopidogrel on restoring platelet function by donor platelets.
Topics: Adenosine; Adenosine Diphosphate; Aged; Blood Platelets; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Female; Flow Cytometry; Half-Life; Humans; Male; Middle Aged; Piperazines; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Transfusion; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Thiophenes; Ticagrelor; Ticlopidine | 2015 |
Differential effects of platelets and platelet inhibition by ticagrelor on TLR2- and TLR4-mediated inflammatory responses.
Topics: Adenosine; Adenosine Diphosphate; Adult; Blood Platelets; Cross-Over Studies; Cytokines; Double-Blind Method; Humans; Inflammation; Leukocytes, Mononuclear; Ligands; Lipopolysaccharides; Male; Monocytes; Phagocytosis; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; RNA, Messenger; Ticagrelor; Toll-Like Receptor 2; Toll-Like Receptor 4; Young Adult | 2015 |
Ticagrelor versus prasugrel in patients with high on-clopidogrel treatment platelet reactivity after PCI: The ISAR-ADAPT-PF study.
Topics: Adenosine; Adenosine Diphosphate; Aged; Blood Platelets; Clopidogrel; Comorbidity; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Risk Factors; Ticagrelor; Ticlopidine; Treatment Outcome | 2016 |
Ticagrelor pharmacokinetics and pharmacodynamics in patients with NSTEMI after a 180-mg loading dose.
Topics: Adenosine; Adenosine Diphosphate; Aged; Biotransformation; Blood Platelets; Coronary Artery Disease; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Non-ST Elevated Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Purinergic P2Y Receptor Antagonists; Sweden; Ticagrelor | 2017 |
Effects of ticagrelor monotherapy vs. clopidogrel monotherapy on platelet reactivity: a randomized, crossover clinical study (SINGLE study).
Topics: Adenosine; Adenosine Diphosphate; Aspirin; Blood Platelets; Clopidogrel; Cross-Over Studies; Epinephrine; Fibrinolytic Agents; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticagrelor; Treatment Outcome | 2022 |
Impact of diabetes mellitus on the pharmacodynamic effects of prasugrel and ticagrelor after switching from clopidogrel in patients with coronary artery disease.
Topics: Adenosine; Adenosine Diphosphate; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Diabetes Mellitus; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Prospective Studies; Ticagrelor | 2022 |
910 other study(ies) available for adenosine diphosphate and adenosine
| Article | Year |
|---|---|
Purine derivatives as competitive inhibitors of human erythrocyte membrane phosphatidylinositol 4-kinase.
Topics: 1-Phosphatidylinositol 4-Kinase; Adenine; Adenosine; Adenosine Triphosphate; Binding, Competitive; Chemical Phenomena; Chemistry; Erythrocyte Membrane; Humans; Molecular Structure; Phosphotransferases; Purines; Structure-Activity Relationship | 1990 |
Identification of potent, selective P2Y-purinoceptor agonists: structure-activity relationships for 2-thioether derivatives of adenosine 5'-triphosphate.
Topics: Adenine Nucleotides; Animals; Aorta; Colon; Enzyme Activation; Erythrocyte Membrane; Guinea Pigs; Male; Mesenteric Arteries; Muscle Relaxation; Muscle, Smooth; Rabbits; Receptors, Purinergic P2; Structure-Activity Relationship; Sulfides; Turkeys; Type C Phospholipases; Vas Deferens | 1993 |
Structure-based design of a potent, selective, and irreversible inhibitor of the catalytic domain of the erbB receptor subfamily of protein tyrosine kinases.
Topics: Amino Acid Sequence; Binding Sites; Catalysis; Drug Design; Enzyme Inhibitors; ErbB Receptors; Humans; Molecular Sequence Data; Protein-Tyrosine Kinases; Receptor, ErbB-2; Sequence Homology, Amino Acid; Tumor Cells, Cultured | 1997 |
Synthetic, nondegradable diadenosine polyphosphates and diinosine polyphosphates: their effects on insulin-secreting cells and cultured vascular smooth muscle cells.
Topics: 3T3 Cells; Animals; Cell Division; Cells, Cultured; Dinucleoside Phosphates; In Vitro Techniques; Insulin; Insulin Secretion; Mice; Muscle, Smooth, Vascular; Protein Binding; Rats; Stereoisomerism; Structure-Activity Relationship; Thymidine | 2003 |
Novel adenosine-derived inhibitors of 70 kDa heat shock protein, discovered through structure-based design.
Topics: Adenosine; Cell Line, Tumor; Crystallography, X-Ray; Drug Design; Fluorescence Polarization Immunoassay; HSP70 Heat-Shock Proteins; Humans; Molecular Structure | 2009 |
Identification of critical ligand binding determinants in Mycobacterium tuberculosis adenosine-5'-phosphosulfate reductase.
Topics: Catalytic Domain; Drug Design; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Ligands; Magnesium; Models, Molecular; Mycobacterium tuberculosis; Oxidoreductases Acting on Sulfur Group Donors; Pseudomonas aeruginosa; Static Electricity; Substrate Specificity | 2009 |
Specific interactions between adenosine and streptavidin/avidin.
Topics: Adenosine; Aptamers, Nucleotide; Avidin; Fluorescent Dyes; Kinetics; Protein Binding; Spectrometry, Fluorescence; Streptavidin | 2012 |
Identification of Highly Promising Antioxidants/Neuroprotectants Based on Nucleoside 5'-Phosphorothioate Scaffold. Synthesis, Activity, and Mechanisms of Action.
Topics: Animals; Antioxidants; Cells, Cultured; Drug Discovery; Humans; Hydrogen Peroxide; Hydrolysis; Iron; Models, Molecular; Neurons; Neuroprotective Agents; Nucleosides; Nucleotides; PC12 Cells; Phosphorothioate Oligonucleotides; Purinergic P2Y Receptor Agonists; Rats; Reactive Oxygen Species; Receptors, Purinergic P2Y1 | 2015 |
Exploiting Protein Conformational Change to Optimize Adenosine-Derived Inhibitors of HSP70.
Topics: Adenosine; Crystallography, X-Ray; Dose-Response Relationship, Drug; HSP70 Heat-Shock Proteins; Humans; Models, Molecular; Molecular Conformation; Structure-Activity Relationship | 2016 |
Identification of a selective inhibitor of transforming growth factor β-activated kinase 1 by biosensor-based screening of focused libraries.
Topics: Biosensing Techniques; Humans; Kinetics; MAP Kinase Kinase Kinases; Protein Kinase Inhibitors; Surface Plasmon Resonance | 2017 |
Rational Design of Selective Adenine-Based Scaffolds for Inactivation of Bacterial Histidine Kinases.
Topics: Adenine; Adenosine Triphosphate; Anti-Bacterial Agents; Aspartic Acid; Bacteria; Drug Design; Histidine Kinase; HSP90 Heat-Shock Proteins; Models, Molecular; Molecular Docking Simulation; Structure-Activity Relationship | 2017 |
Inosine-guanosine and adenosine phosphorylase activities in hepatopancreas of Helix pomatia (Gastropoda).
Topics: Adenine Phosphoribosyltransferase; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calorimetry; Guanine; Guanine Nucleotides; Guanosine Triphosphate; Helix, Snails; Hydrogen-Ion Concentration; Hypoxanthine Phosphoribosyltransferase; Kinetics; Liver; Pancreas; Pentosyltransferases; Purine-Nucleoside Phosphorylase; Snails; Structure-Activity Relationship | 1976 |
Effects of photolysable 2-azido analogues of adenosine, AMP and ADP on human platelets.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Humans; Photolysis; Platelet Aggregation; Receptors, Cyclic AMP | 1977 |
[Interaction of intracellular RNAase from Aspergillus clavatus with derivatives of its substrates].
Topics: Acylation; Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aspergillus; Binding Sites; Hydrogen-Ion Concentration; Isomerism; Ribonucleases; Ribosemonophosphates; Spectrophotometry, Ultraviolet; Substrate Specificity | 1978 |
Effects of D- and L- enantiomers of adenosine, AMP and ADP and their 2-chloro- and 2-azido- analogues on human platelets.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Blood Platelets; Cyclic AMP; Humans; Platelet Aggregation; Stereoisomerism | 1979 |
Bovine fibrinogen-induced 14C-serotonin and other compounds release from human blood platelets.
Topics: Acid Phosphatase; Adenosine; Adenosine Diphosphate; Amitriptyline; Animals; Blood Platelets; Cattle; Collagen; Fibrinogen; Humans; Phentolamine; Phosphoenolpyruvate; Platelet Aggregation; Platelet Factor 3; Propranolol; Serotonin | 1975 |
A membrane-bound enzyme in rabbit aorta capable of inhibiting adenosine-diphosphate-induced platelet aggregation.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Aorta; Apyrase; Cell Extracts; Cell Membrane; Phosphoric Monoester Hydrolases; Platelet Aggregation; Rabbits; Thrombosis | 1977 |
Studies in vitro on the effect of adenosine, adenine and NAD on guinea pig myometrium in the presence of exogenously applied PGE2.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Female; Guinea Pigs; Indomethacin; Muscle Contraction; Myometrium; NAD; Prostaglandins E; Uterus | 1979 |
Fibrinogen and ADP-induced platelet aggregation.
Topics: Adenosine; Adenosine Diphosphate; Animals; Blood Platelets; Chromium Radioisotopes; Edetic Acid; Fibrinogen; Humans; Iodine Radioisotopes; Platelet Aggregation; Prostaglandins E; Rabbits | 1978 |
Quantification of the morphological reaction of platelets to aggregating agents and of its reversal by aggregation inhibitors.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood Platelets; Edetic Acid; Egtazic Acid; Microscopy, Electron; Photometry; Platelet Aggregation; Prostaglandins E; Rabbits; Serotonin | 1978 |
Adenine nucleotide metabolism during cardiac hypertrophy and ischemia in rats.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Aorta, Abdominal; Cardiomegaly; Constriction; Heart; Hypoxanthines; Inosine; Ischemia; Male; Myocardium; Physical Exertion; Rats; Thyroxine; Time Factors | 1975 |
[Mechanism of synaptosomal degradation of ATP in connection with involvement of adenosine in the transmission process].
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Adenylate Kinase; Animals; Brain; Nerve Endings; Rats; Synaptosomes | 1975 |
Effects of ischemia on adenine nucleotide metabolism and coronary flow during cardiac hypertrophy.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cardiomegaly; Coronary Circulation; Coronary Disease; Guinea Pigs; Hypoxanthines; Inosine; Rats | 1975 |
A cellular-biochemical evaluation of gastric body mucosa and muscular layer in patients with different basal acid outputs.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; DNA; Gastric Juice; Gastric Mucosa; Humans; Muscle, Smooth; Peptic Ulcer; Phospholipids; RNA; Secretory Rate | 1976 |
Effect of dipyridamole on myocardial adenosine metabolism and coronary flow in hypoxia and reactive hyperemia in the isolated perfused guinea pig heart.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cardiomegaly; Coronary Circulation; Dipyridamole; Guinea Pigs; Hyperemia; Hypoxanthines; Hypoxia; In Vitro Techniques; Inosine; Myocardium | 1976 |
Affinity labeling of AMP-ADP sites in heart phosphofructokinase by 5-p-fluorosulfonylbenzoyl adenosine.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Affinity Labels; Allosteric Site; Animals; Myocardium; Phosphofructokinase-1; Sheep | 1978 |
Action of various adenine derivatives on cerebellar Purkinje cells.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cyclic AMP; Electrophysiology; Iontophoresis; Male; Purkinje Cells; Rats; Structure-Activity Relationship | 1975 |
The effect of ADP, calcium and some inhibitors of platelet aggregation on protein phosphokinases from human blood platelets.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Blood Platelets; Calcium; Cyclic AMP; Cytoplasm; Humans; Kinetics; Membranes; Platelet Aggregation; Protein Kinases | 1975 |
Uptake of adenosine by dispersed chich embryonic cardiac cells.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Age Factors; Aminohydrolases; Animals; Chick Embryo; Heart; In Vitro Techniques; Inosine; Inosine Nucleotides; Myocardium; Phosphotransferases | 1975 |
Aggregation and release in thrombocytes of the duck.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood Platelets; Collagen; Ducks; Glucuronidase; L-Lactate Dehydrogenase; Phosphoric Monoester Hydrolases; Platelet Adhesiveness; Platelet Aggregation; Serotonin | 1975 |
The effects of adenosine triphosphate and adenosine diphosphate on transmission at the rat and frog neuromuscular junctions.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Diaphragm; Drug Interactions; Female; In Vitro Techniques; Male; Membrane Potentials; Neuromuscular Junction; Rana temporaria; Rats; Synaptic Transmission; Tachyphylaxis; Time Factors | 1975 |
In vitro evaluation of inhibitors of platelet release and aggregation.
Topics: Adenosine; Adenosine Diphosphate; Anti-Inflammatory Agents; Antilymphocyte Serum; Aspirin; Blood Platelets; Collagen; Depression, Chemical; Dextrans; Dipyridamole; Epinephrine; Hematology; Humans; Molecular Weight; Phosphoric Monoester Hydrolases; Platelet Adhesiveness; Platelet Aggregation; Propionates; Prostaglandins E; Serotonin; Sulfinpyrazone; T-Lymphocytes | 1975 |
Affinity labeling of the inhibitory DPNH site of bovine liver glutamate dehydrogenase by 5'-fluorosulfonylbenzoyl adenosine.
Topics: Adenosine; Adenosine Diphosphate; Affinity Labels; Animals; Binding Sites; Cattle; Glutamate Dehydrogenase; Guanosine Triphosphate; Kinetics; Liver; NAD; Protein Binding; Spectrophotometry, Ultraviolet | 1975 |
Effects of adenosine on levels of adenosine cyclic 3',5'-monophosphate in human blood platelets in relation to adenosine incorporation and platelet aggregation.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adenosine Diphosphate; Blood Platelets; Cyclic AMP; Guanosine; Humans; In Vitro Techniques; Kinetics; Papaverine; Platelet Aggregation; Prostaglandins E; Xanthines | 1975 |
Characterization of the metabolism of exogenous cyclic AMP by perfused rat heart and incubated prepubertal rat ovary.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cyclic AMP; Female; Metabolic Clearance Rate; Myocardium; Ovary; Phosphoric Diester Hydrolases; Rats; Theophylline; Time Factors | 1975 |
Platelet aggregometry and anti-platelet isoantibodies.
Topics: Adenosine; Adenosine Diphosphate; Adenylate Kinase; Animals; Antilymphocyte Serum; Aspirin; Blood Platelets; Bucladesine; Heparin; HLA Antigens; Immune Sera; Isoantibodies; Platelet Aggregation; Platelet Factor 3; Platelet Factor 4; Prostaglandins E; Snake Venoms; Thrombin | 1975 |
Relation between the inhibition of aggregation and the concentration of cAMP in human and rat platelets.
Topics: Adenosine; Adenosine Diphosphate; Animals; Blood Platelets; Cyclic AMP; Humans; In Vitro Techniques; Mopidamol; Platelet Aggregation; Prostaglandins E; Rats | 1976 |
Concomitant changes in cyclic AMP level and postsynaptic potentials of olfactory cortex slices induced by adenosine derivatives.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cyclic AMP; Guinea Pigs; Limbic System; Male; Membrane Potentials; Synaptic Membranes | 1976 |
Significance of glucose and glycogen metabolism for platelet function.
Topics: Adenosine; Adenosine Diphosphate; Blood Platelets; Bucladesine; Cell Membrane; Cyclic AMP; Energy Metabolism; Glucose; Glucosephosphates; Glycogen; Glycogen Synthase; Humans; In Vitro Techniques; Muscles; Phosphorylase Kinase; Prostaglandins E | 1975 |
Binding of adenosine disphosphate by human platelet membrane.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Blood Platelets; Cell Membrane; Cyclic AMP; Humans; Immunoglobulin Fab Fragments; In Vitro Techniques; Prostaglandins E; Receptors, Drug; Temperature | 1975 |
Incorporation of adenosine into ATP: formation of compartmentalized ATP.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Hypoxanthines; Liver; Liver Neoplasms; Mice; Mice, Nude; Neoplasms, Experimental | 1976 |
Adenosine and adenine nucleotides stimulation of skin (epidermal) adenylate cyclase.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Enzyme Activation; Inosine; Kinetics; Papaverine; Skin; Swine; Theophylline | 1976 |
Inhibition of sympathetic neurotransmission in canine blood vessels by adenosine and adenine nucleotides.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arteries; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Hindlimb; In Vitro Techniques; Norepinephrine; Saphenous Vein; Sympathetic Nervous System; Synaptic Transmission; Vasomotor System | 1977 |
Couplings between the sites for methionine and adenosine 5'-triphosphate in the amino acid activation reaction catalyzed by trypsin-modified methionyl-transfer RNA synthetase from Escherichia coli.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Amino Acyl-tRNA Synthetases; Chemical Phenomena; Chemistry; Dialysis; Diphosphates; Escherichia coli; Kinetics; Methionine; Methionine-tRNA Ligase; Spectrometry, Fluorescence; Trypsin | 1977 |
Properties of human erythrocyte phosphatidylinositol kinase and inhibition by adenosine, ADP and related compounds.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Caffeine; Cyclic AMP; Enzyme Activation; Erythrocytes; Guanine Nucleotides; Humans; Kinetics; Mercaptoethanol; Phosphatidylinositols; Phosphotransferases; Polyethylene Glycols; Theophylline | 1977 |
Elevation of guanosine 3',5'-monophosphate level by adenosine in cerebellar slices of guinea pig.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Cerebellum; Cyclic AMP; Cyclic GMP; Guinea Pigs; In Vitro Techniques; Kinetics; Male; Papaverine; Phosphodiesterase Inhibitors; Theophylline; Xanthines | 1977 |
Control of phosphoribosylpyrophosphate synthesis in human lymphocytes.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Guanine Nucleotides; Guanosine; Humans; Lymphocytes; Phosphoribosyl Pyrophosphate; Phosphotransferases; Ribose-Phosphate Pyrophosphokinase | 1977 |
Observations on the algogenic actions of adenosine compounds on the human blister base preparation.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Blister; Calcium; Cyclic AMP; Humans; Jejunum; Muscle Tonus; Nerve Endings; Pain; Potassium; Rabbits; Skin | 1977 |
The effect of cyclic AMP on human colony forming cell and colony stimulating factor production.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Bone Marrow; Bone Marrow Cells; Bucladesine; Cell Division; Cell Separation; Clone Cells; Colony-Stimulating Factors; Culture Techniques; Cyclic AMP; Glycoproteins; Humans | 1977 |
The purine nucleotide cycle. Studies of ammonia production and interconversions of adenine and hypoxanthine nucleotides and nucleosides by rat brain in situ.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Ammonia; Animals; Brain; Electric Stimulation; Hypoxanthines; Kinetics; Male; NAD; Rats | 1978 |
An adenosine 3':5'-monophosphate/adenosine binding protein from mouse liver. A study of its interaction with synthetic and naturally occurring adenosine derivatives.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Carrier Proteins; Cyclic AMP; Kinetics; Liver; Mice; Structure-Activity Relationship | 1978 |
Adenylate cyclase activity in human liver membranes and its inhibition by adenosine and adenine nucleotides.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Cell Membrane; Cyclic AMP; Fluorides; Glucagon; Guanylyl Imidodiphosphate; Humans; Liver; Proteins | 1978 |
Inhibitory action adenosine, 5-HT (serotonin) and GABA (gamma-aminobutyric acid) on the postsynaptic potential (PSP) or slices from olfactory cortex and superior colliculus in correlation to the level of cyclic AMP.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cyclic AMP; Evoked Potentials; gamma-Aminobutyric Acid; Guinea Pigs; Neural Inhibition; Olfactory Bulb; Serotonin; Superior Colliculi; Synapses; Synaptic Transmission | 1979 |
Uptake and release of adenosine in isolated rat fat cells.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adipose Tissue; Animals; Cyclic AMP; Isoproterenol; Lipid Metabolism; Methoxamine; Norepinephrine; Nucleotidases; Papaverine; Rats; Theophylline | 1979 |
Aggregation of gel-filtered guinea-pig platelets by lipoproteins.
Topics: Adenosine; Adenosine Diphosphate; Animals; Apyrase; Aspirin; Chromatography, Gel; Dipyridamole; Guinea Pigs; Lipoproteins; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Platelet Aggregation; Prostaglandins E | 1979 |
The influence of adenosine on intermediary metabolism of isolated hepatocytes.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cyclic AMP; Energy Metabolism; Female; Gluconeogenesis; In Vitro Techniques; Lactates; Liver; NAD; Organophosphorus Compounds; Oxidation-Reduction; Phosphates; Pyruvates; Rats | 1979 |
Evidence for involvement of protein kinase in the activation by adenosine 3':5'-monophosphate of brain tyrosine 3-monooxygenase.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Brain; Cyclic AMP; Edetic Acid; Enzyme Activation; Magnesium; Male; Protein Kinases; Rats; Tyrosine 3-Monooxygenase | 1975 |
Regulation by nucleotides of 45calcium uptake in homogenates of rat islets of Langerhans.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Bucladesine; Calcium; Calcium Radioisotopes; Cyclic AMP; Guanosine Triphosphate; Hydrogen-Ion Concentration; Islets of Langerhans; Kinetics; Rats; Ribonucleotides; Time Factors; Uracil Nucleotides | 1975 |
Increased incorporation of adenosine into adenine nucleotide pools in serum-deprived mammalian cells.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Blood; Cell Line; Cells, Cultured; Culture Media | 1978 |
An analysis of the action of ATP and related compounds on membrane current and tension components in bullfrog atrial muscle.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Atrial Function; Heart Atria; In Vitro Techniques; Membrane Potentials; Muscle, Smooth; Myocardial Contraction; Rana catesbeiana | 1977 |
Adenosine analogs and human platelets--II. Inhibition of ADP-induced aggregation by carbocyclic adenosine and imidazole-ring modified analogs. Significance of alterations in the nucleotide pools.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Blood Platelets; Humans; In Vitro Techniques; Nucleotides; Platelet Aggregation; Structure-Activity Relationship | 1979 |
Adenylation and ADP-ribosylation in the mouse 1-cell embryo.
Topics: Adenosine; Adenosine Diphosphate; Animals; Embryo, Mammalian; Embryonic Development; Female; Mice; Poly A; Pregnancy; Ribose; RNA; Time Factors | 1979 |
Myocardial adenosine salvage rates and restoration of ATP content following ischemia.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Coronary Disease; Inosine Monophosphate; Kinetics; Male; Myocardium; Rats | 1979 |
ADP metabolism in vascular tissue, a possible thrombo-regulatory mechanism.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Aorta; Aorta, Thoracic; Blood Coagulation; Blood Vessels; Chromatography, Thin Layer; Guinea Pigs; Inosine; Lung; Male; Muscle, Smooth; Rabbits; Rats; Time Factors | 1979 |
Brain adenosine production in the rat during 60 seconds of ischemia.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Brain; Brain Ischemia; Cerebrovascular Circulation; Homeostasis; Lactates; Phosphocreatine; Pyruvates; Rats; Time Factors | 1979 |
Adenine nucleotide degradation during energy depletion in human lymphoblasts. Adenosine accumulation and adenylate energy charge correlation.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Blood Proteins; Cell Line; Chromatography, High Pressure Liquid; Energy Metabolism; Humans; Lymphocytes; Rotenone | 1979 |
Accumulation of [3H]ATP in small dense core vesicles of superfused vasa deferentia.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Castration; Male; Microsomes; Mitochondria; Norepinephrine; Rats; Vas Deferens | 1979 |
Vascular endothelial and smooth muscle cells in culture selectively release adenine nucleotides.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Aorta; Cell Membrane Permeability; Endothelium; Muscle, Smooth; Platelet Aggregation; Swine | 1979 |
Effect of platelet activation on the platelet surface sialic acid.
Topics: Adenosine; Adenosine Diphosphate; Aspirin; Blood Platelets; Cell Membrane; Collagen; Epinephrine; Humans; Neuraminidase; Sialic Acids; Thrombin | 1979 |
Relative vasodilator potency of ATP, ADP, AMP and adenosine (Ado) in the cat hind limb.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cats; Female; Hindlimb; Male; Regional Blood Flow; Skin Physiological Phenomena; Time Factors; Vasodilator Agents | 1979 |
Adenosine diphosphate metabolism by cultured human umbilical endothelial cells.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Cell Adhesion; Cells, Cultured; Endothelium; Female; Humans; Kinetics; Muscle, Smooth, Vascular; Pregnancy; Umbilicus; Veins | 1979 |
Relaxation of isolated taenia coli of guinea-pig by enantiomers of 2-azido analogues of adenosine and adenine nucleotides.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Colon; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Stereoisomerism | 1979 |
The contribution of adenosine to the inhibitory actions of adenine nucleotides on the guinea-pig taenia coli: studies with phosphate-modified adenine nucleotide analogs and dipyridamole.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Colon; Dipyridamole; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Phosphates | 1979 |
Collagen-induced platelet aggregation:--evidence against the essential role of platelet adenosine diphosphate.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Blood Platelets; Collagen; Humans; Platelet Aggregation; Serotonin; Sheep | 1979 |
Spontaneous platelet aggregation in cerebrovascular disease.
Topics: Adenosine; Adenosine Diphosphate; Adult; Aged; Aspirin; Blindness; Brain Diseases; Female; Humans; Ischemic Attack, Transient; Male; Middle Aged; Paresthesia; Phentolamine; Platelet Aggregation | 1978 |
Adenosine-3',5'-diphosphate and coenzyme A--effects on platelet function.
Topics: Adenosine; Adenosine Diphosphate; Blood Platelets; Coenzyme A; Humans; In Vitro Techniques; Platelet Aggregation; Serotonin | 1978 |
The effect of prostaglandin E1 and adenosine on adverse platelet reactions during charcoal haemoperfusion.
Topics: Adenosine; Adenosine Diphosphate; Charcoal; Filtration; Hemoperfusion; Humans; Microscopy, Electron, Scanning; Platelet Aggregation; Pressure; Prostaglandins E | 1978 |
Comparative degradation of adenylnucleotides by cultured endothelial cells and fibroblasts.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Cell Adhesion; Cells, Cultured; Endothelium; Female; Fibroblasts; Humans; Inosine; Male; Skin; Umbilical Cord | 1978 |
Synthesis, storage and drug-induced release of atp-8-3h in the perfused bovine adrenal gland.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adrenal Glands; Aminophylline; Animals; Barium; Carbachol; Catecholamines; Cattle; Depression, Chemical; Edetic Acid; Stimulation, Chemical; Time Factors | 1975 |
Studies on human platelets stored at 20-22 degrees C without agitation.
Topics: Adenosine; Adenosine Diphosphate; Blood Cell Count; Blood Platelets; Blood Preservation; Blood Transfusion; Collagen; Epinephrine; Glycogen; Humans; Osmotic Pressure; Platelet Aggregation; Platelet Factor 3; Serotonin; Temperature; Thrombin; Time Factors | 1976 |
Characteristics of the relaxant response of adenosine and its analogs in intestinal smooth muscle.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Drug Interactions; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Rabbits; Sympathetic Nervous System; Time Factors | 1977 |
Membrane changes during cartilage maturation. Increase in 5'-nucleotidase and decrease in adenosine inhibition of adenylate cyclase.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenylyl Cyclase Inhibitors; Animals; Cartilage; Cell Membrane; Chick Embryo; Epiphyses; Kinetics; Levamisole; Nucleotidases | 1977 |
Effect of thio reagents on platelet transport processes and responses to stimuli.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Biological Transport, Active; Blood Platelets; Collagen; Humans; In Vitro Techniques; Platelet Aggregation; Serotonin; Stimulation, Chemical; Sulfhydryl Reagents | 1977 |
Effect of dipyridamole and its monoglucuronide derivative on adenosine uptake by human platelets and ADP-induced platelet aggregation.
Topics: Adenosine; Adenosine Diphosphate; Blood Platelets; Depression, Chemical; Dipyridamole; Drug Interactions; Glucuronates; Glycoproteins; Humans; In Vitro Techniques; Platelet Aggregation; Protein Binding | 1977 |
Antagonism by methylxanthines of purine nucleotide-and dipyridamole-induced inhibition of peristaltic activity of the guinea pig ileum.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Aminophylline; Animals; Dipyridamole; Electric Stimulation; Gastrointestinal Motility; Guinea Pigs; Hydroxydopamines; Ileum; In Vitro Techniques; Male; Parasympatholytics; Peristalsis; Purine Nucleotides; Reserpine; Theophylline; Xanthines | 1977 |
Sephadex-induced reduction of coronary flow in the isolated rat heart: a model for ischemic heart disease.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Blood Pressure; Coronary Disease; Disease Models, Animal; Hypoxanthines; Hypoxia; In Vitro Techniques; Inosine; Male; Microspheres; Myocardial Contraction; Myocardium; Perfusion; Phosphocreatine; Polysaccharides; Rats; Sepharose | 1977 |
Adenosine derivatives for dehydrogenases and kinases.
Topics: Adenosine; Adenosine Diphosphate; Affinity Labels; Animals; Benzenesulfonates; Cattle; Glutamate Dehydrogenase; Humans; Kinetics; Methods; Pyruvate Kinase; Rabbits | 1977 |
Evidence for enhanced uptake of ATP by liver and kidney in hemorrhagic shock.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Inosine; Kidney; Liver; Magnesium; Rats; Shock, Hemorrhagic | 1977 |
Identification of separate receptors for adenosine and adenosine 5'-triphosphate in causing relaxations of the isolated taenia of the guinea-pig caecum.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cecum; Dipyridamole; Female; Guinea Pigs; Isatin; Muscle Contraction; Purines; Receptors, Drug | 1976 |
Studies on adenine and adenosine metabolism by intact human erythrocytes using high performance liquid chromatography.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Blood Glucose; Chromatography, High Pressure Liquid; Erythrocytes; Glycolysis; Humans; Inosine Nucleotides; Kinetics; Lactates; Purines | 1976 |
Fibrin-induced release of platelet serotonin.
Topics: Adenosine; Adenosine Diphosphate; Blood Platelets; Calcium; Fibrin; Fibrinogen; Hirudins; Humans; Platelet Adhesiveness; Platelet Aggregation; Prostaglandins E; Serotonin; Thrombin | 1976 |
The interconversion of purine nucleotides during Ilyanassa embryogenesis.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Guanine Nucleotides; Snails | 1976 |
[Structure of electrochemically reduced adenine nucleotides. Their interaction with inorganic phosphate].
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Chemical Phenomena; Chemistry; Electrolysis | 1976 |
The relaxant effect of adenosine-5'-alpha, beta-methylenediphosphonate on the longitudinal smooth muscle of the rabbit ileum.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Diphosphonates; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Parasympathetic Nervous System; Rabbits; Sympathetic Nervous System | 1976 |
Nucleotide rigidity.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Oligonucleotides; Poly A; Poly U; RNA, Transfer; Uracil Nucleotides | 1976 |
Uptake of ATP by liver and kidney in vitro.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Extracellular Space; In Vitro Techniques; Kidney; Liver; Nucleotides; Rats | 1976 |
Rat platelet aggregation by ATP. Aggregometrical and ultrastructural comparison with aggregations induced by ADP and collagen.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Apyrase; Aspirin; Blood Platelets; Collagen; Female; Humans; Male; Platelet Aggregation; Rats | 1976 |
Effect of ischemia and infarction on regional content of adenine nucleotides and derivatives in canine left ventricle.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Coronary Disease; Dogs; Female; Heart Ventricles; Hypoxanthines; Inosine; Male; Myocardial Infarction; Myocardium | 1976 |
[Interaction of adenine derivatives with chloroplast membranes].
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adsorption; Cell Membrane; Chloroplasts; Photophosphorylation | 1976 |
Microvascular haemostasis and the effect of local stimulation and inhibition of platelet function. An experimental study in rabbits.
Topics: Adenosine; Adenosine Diphosphate; Animals; Blood Platelets; Female; Hemostasis; Heparin; Lasers; Male; Mesentery; Microcirculation; Prostaglandins E; Rabbits; Thrombin; Time Factors | 1976 |
Inhibition of H+ secretion in the frog gastric mucosa by ATP and related compounds.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Chlorides; Dose-Response Relationship, Drug; Gastric Mucosa; Hydrogen; Magnesium; Membrane Potentials; Rana pipiens | 1976 |
Detailed purine salvage metabolism in and outside the free malarial parasite.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Blood; Buffers; Chromatography, Thin Layer; Hypoxanthines; Inosine; Inosine Nucleotides; Mice; Microscopy, Electron, Scanning; Oxidative Phosphorylation; Plasmodium berghei; Purines; Tritium | 1975 |
Studies on mammalian ribonucleotide reductase inhibition by pyridoxal phosphate and the dialdehyde derivatives of adenosine, adenosine 5'-monophosphate, and adenosine 5'-triphosphate.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aldehydes; Animals; Borohydrides; Carcinoma, Ehrlich Tumor; Cytosine Nucleotides; Hot Temperature; In Vitro Techniques; Mice; Mice, Inbred ICR; Pyridoxal; Pyridoxal Phosphate; Pyridoxamine; Pyridoxine; Ribonucleotide Reductases | 1975 |
Adenosine metabolism in cultured chick-embryo heart cells.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aminophylline; Animals; Carbon Radioisotopes; Cells, Cultured; Chick Embryo; Dipyridamole; Drug Interactions; Hypoxanthines; Inosine; Myocardium; Oxygen | 1975 |
Thermodynamics of complex formation between bovine liver glutamate dehydrogenase and analogs of ADP.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Binding Sites; Calorimetry; Cattle; Deoxyribonucleotides; Glutamate Dehydrogenase; Kinetics; Ligands; Liver; Mathematics; Protein Binding; Structure-Activity Relationship; Thermodynamics | 1975 |
The effect of ATP and related compounds on spontaneous mechanical activity in the rat portal vein.
Topics: Acetylcholine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Depression, Chemical; Drug Interactions; Female; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Portal Vein; Rats; Stimulation, Chemical; Theophylline; Vascular Resistance | 1975 |
[Adsorption chromatography of the nitrogenous bases of nucleic acids and their derivatives on sephadex G-10 columns].
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Azaguanine; Chromatography; Cytosine; Cytosine Nucleotides; Guanine; Hypoxanthines; Nucleic Acids; Nucleotides; Pyrimidine Nucleotides; Uracil; Xanthines | 1975 |
Binding of adenosine diphosphate to intact human platelets.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Binding Sites; Blood Platelets; Centrifugation; Dipyridamole; Guinea Pigs; Humans; Oils; Prostaglandins E; Silicones; Temperature | 1975 |
Effects of adenine nucleotides on rice-root adenosine triphosphate sulphurylase activity in vitro.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Cytosol; Kinetics; Nucleotidyltransferases; Oryza; Plants; Sulfates | 1975 |
The effect of metoclopramide on inhibition induced by purine nucleotides, noradrenaline, and theophylline ethylenediamine on intestinal muscle and on peristalsis in vitro.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Colon; Duodenum; Ethylenediamines; Gastrointestinal Motility; Guinea Pigs; Ileum; Male; Metoclopramide; Muscle, Smooth; Norepinephrine; Organ Specificity; Peristalsis; Purine Nucleotides; Rabbits; Rats; Species Specificity; Theophylline | 1975 |
Release of adenosine by hypoxic canine lung tissue and its possible role in pulmonary circulation.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Dogs; Guinea Pigs; Histocytochemistry; Hypoxia; Lung; Microscopy, Electron; Phosphorylase Phosphatase; Pulmonary Circulation; Rats; Vascular Resistance | 1975 |
Adenosine analogs and human platelets. Effects on nucleotide pools and the aggregation phenomenon.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Blood Platelets; Chromatography, Liquid; Depression, Chemical; Humans; In Vitro Techniques; Nucleotides; Platelet Aggregation; Ribose; Thrombin; Time Factors | 1975 |
Effect of adenosine on the adenine nucleotide content and metabolism of hepatocytes.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Female; Gluconeogenesis; In Vitro Techniques; Ketone Bodies; Kidney Tubules; Lactates; Liver; Oxygen Consumption; Phosphates; Rats; Time Factors; Urea | 1975 |
Brain energy metabolism during the process of dying and after cardiopulmonary resuscitation.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Blood Pressure; Body Temperature; Brain; Death; Energy Metabolism; Glucose; Hypoxia, Brain; Lactates; Male; Phosphocreatine; Pyruvates; Rats; Resuscitation | 1976 |
Synthesis of nucleotides in adrenal medulla and their uptake into chromaffin granules.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adrenal Medulla; Animals; Catecholamines; Cattle; Chromaffin System; In Vitro Techniques; Nucleotides; Phosphates; Phosphorus Radioisotopes; Time Factors | 1976 |
The postanoxic regeneration of 5'-adenosine nucleotides in rabbit kidney tissue during in vitro perfusion.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Female; Hypoxanthines; Hypoxia; Inosine; Kidney; Male; Organ Preservation; Perfusion; Purines; Rabbits; Regeneration; Ribose | 1976 |
Effects of adenosine administration on the function and membrane composition of liver mitochondria in carbon tetrachloride-induced cirrhosis.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Carbon Tetrachloride; Cholesterol; Collagen; Electron Transport Complex IV; Energy Metabolism; Fluorescence Polarization; Intracellular Membranes; Liver Cirrhosis, Experimental; Malates; Male; Membrane Potentials; Mitochondria, Liver; Mitochondrial Swelling; NAD; Oxidation-Reduction; Oxygen Consumption; Phospholipids; Rats; Rats, Inbred Strains | 1992 |
Functional implications of cAMP and Ca2+ on prostaglandin I2 and thromboxane A2 synthesis by human endothelial cells.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Caffeine; Calcimycin; Calcium; Cells, Cultured; Cyclic AMP; Endothelium, Vascular; Epoprostenol; Humans; Kinetics; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2 | 1992 |
Regulation of extracellular adenosine production by ectonucleotidases of adult rat ventricular myocytes.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cell Count; Extracellular Space; Female; Heart Ventricles; Hydrolysis; Myocardium; Nucleotidases; Nucleotides; Rats; Rats, Inbred Strains | 1992 |
The control of actin nucleotide exchange by thymosin beta 4 and profilin. A potential regulatory mechanism for actin polymerization in cells.
Topics: Actins; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Binding, Competitive; Blood Platelets; Contractile Proteins; Humans; Microfilament Proteins; Phosphatidylinositols; Profilins; Thymosin | 1992 |
Specificity and affinity of binding of phosphate-containing compounds to CheY protein.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Bacterial Proteins; Binding Sites; Guanosine Triphosphate; Kinetics; Magnetic Resonance Spectroscopy; Membrane Proteins; Methyl-Accepting Chemotaxis Proteins; Nucleotides; Phosphates; Phosphoric Monoester Hydrolases; Phosphorus; Phosphorylation; Protein Binding; Protons; Sensitivity and Specificity; Thymine Nucleotides; Uridine Triphosphate | 1992 |
G-protein-mediated activation of turkey erythrocyte phospholipase C by beta-adrenergic and P2y-purinergic receptors.
Topics: Adenosine; Adenosine Diphosphate; Adrenergic beta-Antagonists; Animals; Enzyme Activation; Erythrocyte Membrane; Erythrocytes; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Inositol; Isoproterenol; Kinetics; Phosphatidylinositols; Propranolol; Receptors, Adrenergic, beta; Receptors, Purinergic; Thionucleotides; Turkeys; Type C Phospholipases | 1992 |
Antidiuretic effects of purinoceptor agonists injected into the hypothalamic paraventricular nucleus of water-loaded, ethanol-anesthetized rats.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Diuresis; Ethanol; Male; Osmotic Pressure; Paraventricular Hypothalamic Nucleus; Quinidine; Rats; Rats, Wistar; Receptors, Purinergic; Stereotaxic Techniques; Theophylline; Time Factors | 1992 |
Interaction of nucleotide affinity analog 5'-p-fluorosulfonylbenzoyladenosine with platelet ADP receptor: aggregin.
Topics: Adenosine; Adenosine Diphosphate; Affinity Labels; Blood Platelets; Fibrinogen; Humans; Iodine Radioisotopes; Kinetics; Microscopy, Electron, Scanning; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptors, Purinergic; Tritium | 1992 |
[Modulating effects of adenosine on the process of human platelet activation].
Topics: Adenosine; Adenosine Diphosphate; Humans; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Serotonin | 1992 |
Stable adenine nucleotides inhibit [3H]-noradrenaline release in rabbit brain cortex slices by direct action at presynaptic adenosine A1-receptors.
Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cerebral Cortex; Drug Interactions; Drug Stability; Electric Stimulation; Female; Male; Nerve Endings; Norepinephrine; Purinergic Antagonists; Rabbits; Receptors, Purinergic; Suramin; Synapses; Theophylline; Tritium; Xanthines | 1992 |
Low dose infusion of adenosine diphosphate prolongs bleeding time in rats and rabbits.
Topics: Adenosine; Adenosine Diphosphate; Animals; Bleeding Time; Blood Coagulation; Dose-Response Relationship, Drug; Female; Infusions, Intravenous; Platelet Aggregation; Rabbits; Rats | 1992 |
The human platelet as a reproducible and sensitive cell for the detection and assay of platelet-activating factor.
Topics: Adenosine; Adenosine Diphosphate; Adult; Biological Assay; Blood Platelets; Citric Acid; Female; Fibrinogen; Glucose; Humans; In Vitro Techniques; Male; Platelet Activating Factor; Platelet Aggregation; Reproducibility of Results; Serotonin | 1992 |
8-Azidoadenosine and ribonucleotide reductase.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Allosteric Regulation; Animals; Azides; Cytidine Diphosphate; Mice; NADP; Ribonucleotide Reductases; Tumor Cells, Cultured | 1992 |
Small bowel tissue high-energy phosphate alterations during hypothermic storage using different protecting solutions.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Allopurinol; Animals; Cryopreservation; Glucose; Glutathione; Hypertonic Solutions; Insulin; Intestine, Small; Male; Mannitol; Organ Preservation; Organ Preservation Solutions; Potassium Chloride; Procaine; Raffinose; Rats; Rats, Inbred Strains; Solutions | 1992 |
Goblet cell degranulation in isolated canine tracheal epithelium: response to exogenous ATP, ADP, and adenosine.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cell Degranulation; Collodion; Culture Techniques; Dogs; Epithelial Cells; Epithelium; Male; Receptors, Purinergic; Trachea | 1992 |
HPLC determination of adenine compounds as fluorescent derivatives in canine red blood cells.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Chromatography, High Pressure Liquid; Dogs; Erythrocytes; Sensitivity and Specificity | 1992 |
Myocardial adenosine formation during hypoxia: effects of ecto-5'-nucleotidase inhibition.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Guinea Pigs; Heart; Hypoxia; In Vitro Techniques; Male; Myocardium; Perfusion; Vascular Resistance | 1992 |
Determination of concentrations of adenosine and other purines in human term placenta by reversed-phase high-performance liquid chromatography with photodiode-array detection: evidence for pathways of purine metabolism in the placenta.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Chromatography, High Pressure Liquid; Female; Guanine; Humans; NAD; NADP; Placenta; Pregnancy; Purines | 1992 |
Successful transplantation after long-term preservation of dog hearts.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Dogs; Heart; Heart Transplantation; Inosine; Myocardial Reperfusion Injury; Myocardium; Organ Preservation; Piperazines; Time Factors | 1992 |
A2 and P2 purine receptor interactions and surfactant secretion in primary cultures of type II cells.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); AMP Deaminase; Animals; Cells, Cultured; Cyclic AMP; Inositol 1,4,5-Trisphosphate; Lung; Phosphatidylcholines; Pulmonary Surfactants; Receptors, Purinergic; Terbutaline; Theophylline; Thionucleotides; Xanthines | 1991 |
Extracellular metabolism of adenine nucleotides and adenosine in the innervated skeletal muscle of the frog.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cations; Coformycin; Dipyridamole; In Vitro Techniques; Inosine Monophosphate; Kinetics; Muscles; Piperazines; Rana ridibunda; Sodium-Potassium-Exchanging ATPase; Thioinosine | 1991 |
Anti-aggregatory effects of physiological concentrations of adenosine in human whole blood as assessed by filtragometry.
Topics: Adenosine; Adenosine Diphosphate; Dipyridamole; Filtration; Humans; In Vitro Techniques; Male; Platelet Aggregation; Platelet Aggregation Inhibitors | 1991 |
Segregation of discrete GS alpha-mediated responses that accompany homologous or heterologous desensitization in two related somatic hybrids.
Topics: Adenosine; Adenosine Diphosphate; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Cell Line; Epoprostenol; GTP-Binding Proteins; Hybrid Cells; Iloprost; Kinetics; Mice; Morphine; Neuroblastoma; Phosphorus Radioisotopes; Receptors, Epoprostenol; Receptors, Prostaglandin; Sodium Fluoride | 1990 |
The role of adenosine in the hyperaemic response of the hepatic artery to portal vein occlusion (the 'buffer response').
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Dogs; Dose-Response Relationship, Drug; Female; Hepatic Artery; Hyperemia; In Vitro Techniques; Male; Portal Vein; Theophylline | 1990 |
The stimuli releasing histamine from murine bone marrow-derived mast cells. 2. Mechanisms involved in histamine release induced by extracellular ATP and its metabolites.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Bone Marrow Cells; Cells, Cultured; Histamine Release; Mast Cells; Mice | 1991 |
Adenine nucleotide release from isolated perfused guinea pig hearts and extracellular formation of adenosine.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Coronary Disease; Extracellular Space; Female; Guinea Pigs; Hemodynamics; Isoproterenol; Myocardium; Oxygen; Partial Pressure; Perfusion | 1991 |
Extracellular ATP stimulates steroidogenesis in bovine adrenocortical fasciculata cells via P2 purinoceptors.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cattle; Cells, Cultured; Hydrocortisone; Receptors, Purinergic; Theophylline; Zona Fasciculata | 1991 |
Preservation of adenine nucleotides following ischemia and reperfusion: correlation with functional recovery.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Blood Pressure; Cardioplegic Solutions; Coronary Disease; Female; Heart; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Male; Myocardium; Reperfusion; Swine | 1991 |
Mechanisms of protection of hepatocytes at anoxia and reoxygenation by the xanthine oxidase inhibitor oxypurinol.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cell Hypoxia; Cells, Cultured; Hypoxanthine; Hypoxanthines; Inosine Monophosphate; Kinetics; Liver; Male; Oxygen; Oxypurinol; Rats; Rats, Inbred Strains; Time Factors; Xanthine Oxidase | 1991 |
Adenine nucleotide degradation in cultured chick heart muscle cells.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cells, Cultured; Chick Embryo; Chromatography, High Pressure Liquid; Dipyridamole; Glycolysis; Inosine; Myocardium; Oxidative Phosphorylation; Phosphorylation; Thioinosine | 1991 |
Adenosine and ATP produce vasoconstriction in the feline pulmonary vascular bed by different mechanisms.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cats; Cyclooxygenase Inhibitors; Fatty Acids, Unsaturated; Hydrazines; Lung; Meclofenamic Acid; Phenylisopropyladenosine; Purinergic Antagonists; Receptors, Prostaglandin; Receptors, Purinergic; Receptors, Thromboxane; Thromboxane A2; Vasoconstriction; Vasodilator Agents; Xanthines | 1991 |
In vitro inhibition of platelet aggregation by the liver with UW solution as the preservation fluid.
Topics: Adenosine; Adenosine Diphosphate; Allopurinol; Collagen; Dose-Response Relationship, Drug; Glucose; Glutathione; Humans; Hypertonic Solutions; In Vitro Techniques; Insulin; Liver Transplantation; Mannitol; Organ Preservation; Organ Preservation Solutions; Platelet Aggregation; Platelet Aggregation Inhibitors; Potassium Chloride; Procaine; Raffinose; Ristocetin; Solutions | 1991 |
Inhibition of ADP-induced platelet shape change and aggregation by o-phthalaldehyde: evidence for covalent modification of cysteine and lysine residues.
Topics: Adenosine; Adenosine Diphosphate; Affinity Labels; Blood Platelets; Cysteine; Ethylmaleimide; Humans; Kinetics; Lysine; o-Phthalaldehyde; Platelet Aggregation; Platelet Aggregation Inhibitors; Spectrometry, Fluorescence | 1991 |
Effects of hypothermic ischemia on purine catabolism in canine, primate, and human myocardium.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Dogs; Heart Arrest, Induced; Heart Transplantation; Humans; Hypothermia, Induced; Inosine; Myocardium; Papio; Phosphocreatine; Purines; Species Specificity; Xanthines | 1991 |
Extracellular ATP shows synergistic enhancement of DNA synthesis when combined with agents that are active in wound healing or as neurotransmitters.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Imidodiphosphate; Animals; Cells, Cultured; Cholera Toxin; Colforsin; DNA; DNA Replication; Drug Synergism; Epidermal Growth Factor; Insulin; Keratinocytes; Kinetics; Mice; Mice, Inbred BALB C; Neurotransmitter Agents; Platelet-Derived Growth Factor; Thymidine; Transforming Growth Factors; Tritium; Vasoactive Intestinal Peptide; Wound Healing | 1990 |
Evidence against purines being neurotransmitters of non-adrenergic, non-cholinergic nerves in rat duodenum.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Autonomic Nervous System; Duodenum; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurotransmitter Agents; Purines; Rats; Rats, Inbred Strains; Tetrodotoxin; Theophylline | 1990 |
Metabolic correlates of adenosine formation in stimulated guinea pig heart.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Blood Pressure; Guinea Pigs; Heart; Magnetic Resonance Spectroscopy; Male; Myocardium; Norepinephrine; Oxygen; Oxygen Consumption; Phosphocreatine; Phosphorus Isotopes; Phosphorylation | 1991 |
Endothelium-dependent hyperpolarization elicited by adenine compounds in rabbit carotid artery.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Calcium; Carotid Arteries; Cell Membrane; Electrophysiology; Endothelium, Vascular; Kinetics; Male; Membrane Potentials; Rabbits | 1991 |
Effects of atherosclerosis and regression on vascular responses to products of activated platelets in primates.
Topics: Adenosine; Adenosine Diphosphate; Animals; Arteries; Arteriosclerosis; Blood Platelets; Hemodynamics; Humans; Lipids; Macaca fascicularis; Male; Platelet Activation; Platelet Aggregation; Thrombin; Vasoconstriction; Vasodilation | 1991 |
The roles of ADP2- and Mg2+ in control steps of phosphoglycerate kinase.
Topics: Adenosine; Adenosine Diphosphate; Amino Acid Sequence; Binding Sites; Kinetics; Magnesium; Magnetic Resonance Spectroscopy; Models, Molecular; Phosphoglycerate Kinase; Protein Binding; Protein Conformation; Saccharomyces cerevisiae | 1991 |
Extracellular ATP and adenosine modulate tumor necrosis factor-induced lysis of L929 cells in the presence of actinomycin D.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aminophylline; Cell Line; Cytotoxicity, Immunologic; Dactinomycin; Dose-Response Relationship, Drug; Guanosine Triphosphate; Humans; Phenylisopropyladenosine; Tumor Necrosis Factor-alpha | 1991 |
Roles of adenosine and theophylline on the recovery of adenine nucleotides in postischemic cultured renal tubular cells.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cells, Cultured; Ischemia; Kidney Tubules; Rabbits; Theophylline | 1991 |
Inhibition of adenosine-diphosphate- and collagen-induced platelet aggregation in vitro by UW solution.
Topics: Adenosine; Adenosine Diphosphate; Allopurinol; Collagen; Glutathione; Humans; Hypertonic Solutions; In Vitro Techniques; Insulin; Organ Preservation Solutions; Platelet Aggregation; Platelet Aggregation Inhibitors; Raffinose; Ristocetin; Solutions | 1991 |
Chromatographic behaviour of cyclodextrin complexes of nucleotides, nucleosides and their bases.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Chromatography, Liquid; Cyclodextrins; Nucleosides; Nucleotides; Thymidine; Thymine; Uracil; Uridine | 1990 |
Coronary reactivity in the porcine heart after short lasting myocardial ischaemia: effects of duration of ischaemia and myocardial stunning.
Topics: Adenosine; Adenosine Diphosphate; Animals; Blood Volume; Coronary Circulation; Coronary Disease; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Ligation; Male; Swine; Time Factors; Vasodilation | 1990 |
ADP and glucose as possible synergistic partners in the stimulation of liver glycogen synthase activation.
Topics: Adenosine; Adenosine Diphosphate; Animals; Cytidine Diphosphate; Drug Synergism; Enzyme Activation; Glucose; Glycogen Synthase; Glycogen-Synthase-D Phosphatase; Guanosine Diphosphate; Kinetics; Liver; Male; Rats; Rats, Inbred Strains; Theophylline; Uridine Diphosphate | 1990 |
Role of AMP on the activation of glycogen synthase and phosphorylase by adenosine, fructose, and glutamine in rat hepatocytes.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cells, Cultured; Enzyme Activation; Fructose; Glutamine; Glycogen Synthase; Kinetics; Liver; Male; Models, Biological; Phosphorylase a; Phosphorylases; Rats; Rats, Inbred Strains | 1990 |
Tyrosine alpha 244 is derivatized when the bovine heart mitochondrial F1-ATPase is inactivated with 5'-p-fluorosulfonylbenzoylethenoadenosine.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Alkylating Agents; Animals; Binding Sites; Cattle; Chemical Phenomena; Chemistry; Enzyme Activation; Hydrolysis; Inosine Triphosphate; Kinetics; Magnesium; Mitochondria, Heart; Phosphates; Proton-Translocating ATPases; Tyrosine | 1990 |
Adenosine and its derivatives control human monocyte differentiation into highly accessory cells versus macrophages.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Antigen-Presenting Cells; Cell Differentiation; Cell Survival; Cells, Cultured; Cyclic AMP; Humans; Indomethacin; Macrophages; Mitogens; Monocytes | 1990 |
Direct injection of blood samples into a high-performance liquid chromatographic adenine analyser to measure adenine, adenosine, and the adenine nucleotides with fluorescence detection.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Chromatography, High Pressure Liquid; Cricetinae; Cyclic AMP; Fluorescence; Humans; Injections; Rats | 1990 |
Ins(1,4,5)P3 formation and fluctuating chloride current response induced by external ATP in Xenopus oocytes injected with embryonic guinea pig brain mRNA.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Brain; Calcium; Chlorides; Electric Conductivity; Gallic Acid; Guinea Pigs; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Microinjections; Receptors, Purinergic; RNA, Messenger; Xenopus laevis | 1990 |
Pathways of purine metabolism in human adipocytes. Further evidence against a role of adenosine as an endogenous regulator of human fat cell function.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Kinase; Adenosine Monophosphate; Adenosine Triphosphate; Adipose Tissue; Glycerophosphates; Humans; Hypoxanthine; Hypoxanthines; Inosine; Inosine Monophosphate; Isoproterenol; Lipolysis; Pentostatin; Purines; Tubercidin | 1990 |
Exogenous adenine nucleotides replete endothelial cell adenosine triphosphate after oxidant injury by adenosine uptake.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Cell Membrane; Cells, Cultured; Chromatography, High Pressure Liquid; Endothelium, Vascular; Humans; Hydrogen Peroxide; Hypoxanthine; Hypoxanthines; Inosine; L-Lactate Dehydrogenase; Oxidation-Reduction; Time Factors; Umbilical Veins | 1990 |
Nerve and drug-induced release of adenine nucleosides and nucleotides from rabbit aorta.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Aorta; Chromatography, High Pressure Liquid; Electric Stimulation; Endothelium, Vascular; Male; Methoxamine; Muscle, Smooth, Vascular; Prazosin; Rabbits | 1990 |
A new method of sampling blood for measurement of plasma adenosine.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Blood Specimen Collection; Carbon Radioisotopes; Catheterization; Dipyridamole; Humans | 1990 |
The actions of adenosine 5'-triphosphate on guinea-pig intracardiac neurones in culture.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Animals, Newborn; Cells, Cultured; Electrodes; Guinea Pigs; Heart; Membrane Potentials; Neurons; Nucleotides; Potassium Channels | 1990 |
Evidence that A2 purinoceptors are involved in endothelium-dependent relaxation of the rat thoracic aorta.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta, Thoracic; Endothelium, Vascular; Hemoglobins; In Vitro Techniques; Indomethacin; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Norepinephrine; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline | 1990 |
Release of adenosine and its metabolites from activated human leucocytes.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Basophils; Calcimycin; Dose-Response Relationship, Drug; Histamine Release; Humans; Hypoxanthines; Immunoglobulin E; Inosine; Leukocytes; N-Formylmethionine Leucyl-Phenylalanine; Time Factors | 1986 |
AH6809, a prostaglandin DP-receptor blocking drug on human platelets.
Topics: 1-Methyl-3-isobutylxanthine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine; Adenosine Diphosphate; Adenosine-5'-(N-ethylcarboxamide); Dinoprost; Epoprostenol; Humans; Hydantoins; In Vitro Techniques; Male; Platelet Activating Factor; Platelet Aggregation; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; Receptors, Immunologic; Receptors, Prostaglandin; Xanthenes; Xanthones | 1988 |
Regulation of human neutrophil functions by adenine nucleotides.
Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Cell-Free System; Chemotaxis, Leukocyte; Cytoplasmic Granules; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Purine Nucleotides; Superoxides | 1989 |
Turnover of adenosine in plasma of human and dog blood.
Topics: 5'-Nucleotidase; Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosylhomocysteinase; Animals; Blood Flow Velocity; Dipyridamole; Dogs; Forearm; Half-Life; Humans; Hydrolases; Nucleotidases; Tritium | 1989 |
Thrombin-induced platelet aggregation involves an indirect proteolytic cleavage of aggregin by calpain.
Topics: Adenosine; Adenosine Diphosphate; Affinity Labels; Antipain; Blood Platelets; Calpain; Electrophoresis, Polyacrylamide Gel; Fibrinogen; Humans; Leupeptins; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Protease Inhibitors; Thrombin | 1989 |
The effects of purine nucleotides on transmission in vesical parasympathetic ganglia of the cat.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cats; Dihydroergotamine; Female; Ganglia, Parasympathetic; Male; Norepinephrine; Propranolol; Purine Nucleotides; Synaptic Transmission; Theophylline; Urinary Bladder | 1989 |
In vivo pertussis toxin treatment attenuates some, but not all, adenosine A1 effects in slices of the rat hippocampus.
Topics: Acetylcholine; Adenosine; Adenosine Diphosphate; Animals; Calcium; Cyclic AMP; Electrophysiology; Hippocampus; In Vitro Techniques; Male; Neurons; Norepinephrine; Pertussis Toxin; Phosphorus Radioisotopes; Rats; Rats, Inbred Strains; Receptors, Purinergic; Synapses; Virulence Factors, Bordetella; Yohimbine | 1989 |
Production of AMP and adenosine in the interstitial fluid compartment of the isolated perfused normoxic guinea pig heart.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Extracellular Space; Guinea Pigs; Heart; Hydroxydopamines; Inosine; Male; Myocardium; Oxidopamine; Pyrophosphatases; Sympathectomy, Chemical | 1989 |
Inhibitory effect of adenine nucleotides and anti-allergic drugs on phosphorylation of phosphatidylinositol in rat mast cell granules.
Topics: 1-Phosphatidylinositol 4-Kinase; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Cromolyn Sodium; Cytoplasmic Granules; Histamine H1 Antagonists; Ketotifen; Mast Cells; Phosphatidylinositols; Phosphorylation; Phosphotransferases; Phthalazines; Rats; Theophylline | 1989 |
Adenosine cardioplegia. Adenosine versus potassium cardioplegia: effects on cardiac arrest and postischemic recovery in the isolated rat heart.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Aorta; Blood Pressure; Cardioplegic Solutions; Heart Arrest, Induced; Heart Rate; In Vitro Techniques; Male; Phosphocreatine; Potassium; Rats; Regional Blood Flow; Time Factors | 1989 |
Effects of adenosine and pertussis toxin on lipolysis in adipocytes from exercise-trained male rats.
Topics: Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adipose Tissue; Animals; In Vitro Techniques; Lipolysis; Male; Norepinephrine; Pertussis Toxin; Phenylisopropyladenosine; Physical Conditioning, Animal; Rats; Rats, Inbred Strains; Virulence Factors, Bordetella | 1989 |
[Effects of various physiologic adenine derivatives on the secretion of acid in isolated gastric glands in rabbits].
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Female; Gastric Acid; Gastric Mucosa; Male; Rabbits | 1989 |
Effects of anaerobiosis on adenine nucleotide levels and the release of ATP by Leishmania major promastigotes.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aerobiosis; Anaerobiosis; Animals; Extracellular Space; Hypoxanthine; Hypoxanthines; Leishmania tropica | 1989 |
Transendothelial transport and metabolism of adenosine and inosine in the intact rat aorta.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Aorta; Endothelium, Vascular; Female; Inosine; Male; Muscle, Smooth, Vascular; Purines; Rats; Rats, Inbred Strains; Tritium | 1989 |
Adenosine regulates the respiratory burst of cytokine-triggered human neutrophils adherent to biologic surfaces.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Diphosphate; Cell Adhesion; Cell Aggregation; Humans; Immunosuppressive Agents; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Tumor Necrosis Factor-alpha | 1989 |
Metabolic and pharmacokinetic activity of the isolated sheep bronchial circulation.
Topics: Adenosine; Adenosine Diphosphate; Animals; Bronchi; Dinoprostone; In Vitro Techniques; Oligopeptides; Perfusion; Sheep | 1989 |
The hydrolysis of extracellular adenine nucleotides by arterial smooth muscle cells. Regulation of adenosine production at the cell surface.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Aorta; Cells, Cultured; Hydrolysis; Kinetics; Mathematics; Models, Theoretical; Muscle, Smooth, Vascular; Swine | 1989 |
Inhibition of adenosine deaminase activity reveals an intense active transport of adenosine into neurons in primary cultures.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Biological Transport, Active; Cells, Cultured; Hypoxanthine; Hypoxanthines; Inosine; Mice; Neurons; Nucleoside Deaminases; Pentostatin | 1989 |
Analyses of adenosine and adenine nucleotides in biological materials by fluorescence reaction-high-performance liquid chromatography.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Erythrocyte Membrane; Humans; Mice; Neuroblastoma; Ouabain; Rats; Sodium-Potassium-Exchanging ATPase; Spectrometry, Fluorescence | 1987 |
Evidence for two distinct phosphatidylinositol kinases in fibroblasts. Implications for cellular regulation.
Topics: 1-Phosphatidylinositol 4-Kinase; Adenosine; Adenosine Diphosphate; Animals; Cell Line; Cell Transformation, Neoplastic; Chemical Precipitation; Chromatography, Ion Exchange; Fibroblasts; Isoenzymes; Mice; Phosphotransferases; Platelet-Derived Growth Factor | 1987 |
Effects of purines and forskolin on haemolysis.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Anesthetics, Local; Animals; Bucladesine; Chlorpromazine; Colforsin; Edetic Acid; Hemolysis; In Vitro Techniques; Polyphosphates; Procaine; Purines; Rats; Xanthines | 1987 |
Regulatory effects of adenosine and adenine nucleotides on oxygen radical responses of neutrophils.
Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenosylhomocysteinase; Animals; Antigen-Antibody Complex; Cytochalasin B; Dose-Response Relationship, Drug; Free Radicals; Humans; Hydrogen Peroxide; Hydrolases; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Rats; Superoxides; Tetradecanoylphorbol Acetate; Xanthine Oxidase | 1988 |
Isocratic separation of ATP and its degradation products from biological fluids by automated liquid chromatography.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Autoanalysis; Body Fluids; Chromatography, Liquid; Cyclic AMP; Humans; Hypoxanthine; Hypoxanthines; Inosine; Inosine Monophosphate; Xanthine; Xanthines | 1988 |
Reaction kinetics and inhibition of adenosine kinase from Leishmania donovani.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Kinase; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Kinetics; Leishmania donovani; Methylthioinosine; Phosphotransferases; Substrate Specificity; Tubercidin | 1988 |
Growth inhibition of transformed mouse fibroblasts by adenine nucleotides occurs via generation of extracellular adenosine.
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Apyrase; Biological Transport; Blood; Cell Division; Cell Line, Transformed; Dipyridamole; Fibroblasts; Mice; Nucleotidases; Thioinosine; Uridine Triphosphate | 1988 |
Intracellular adenosine formation and its carrier-mediated release in cultured embryonic chick heart cells.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Biological Transport; Carrier Proteins; Cells, Cultured; Chick Embryo; Deoxyglucose; Dilazep; Dipyridamole; Heart; Hexobendine; Membrane Proteins; Myocardium; Nucleoside Transport Proteins; Nucleotidases; Nucleotides; Oligomycins; Oxygen | 1988 |
ATP stimulates calcium influx in primary astrocyte cultures.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Astrocytes; Calcium; Calcium Channels; Calcium Radioisotopes; Calmodulin; Cell Membrane; Cells, Cultured; Dose-Response Relationship, Drug; Kinetics; Lanthanum; Protein Kinase C; Protein Kinases; Rats; Signal Transduction | 1988 |
Affinity labeling of the ATP-binding site of type II calmodulin-dependent protein kinase by 5'-p-fluorosulfonylbenzoyl adenosine.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Binding Sites; Calcium-Calmodulin-Dependent Protein Kinases; Kinetics; Ligands; Magnesium; Protein Kinase Inhibitors; Protein Kinases | 1988 |
Inhibition of adenosine-metabolizing enzymes modulates mouse sperm fertilizing ability: a changing role for endogenously generated adenosine during capacitation.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Coformycin; Fertilization; Fertilization in Vitro; Male; Mice; Nucleotidases; Sperm Capacitation | 1988 |
On the location and function of the noncatalytic sites on the bovine heart mitochondrial F1-ATPase.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Allosteric Site; Animals; Cattle; Histidine; Hydrogen-Ion Concentration; Kinetics; Macromolecular Substances; Mitochondria, Heart; Proton-Translocating ATPases; Tyrosine | 1988 |
5'-Nucleotidase activity of isolated mature rat cardiac myocytes.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Biological Transport, Active; Female; In Vitro Techniques; Myocardium; Nucleotidases; Rats; Rats, Inbred Strains; Thioinosine | 1985 |
Biochemical studies on 5'-nucleotidase of Schwann cells in degenerated nerve.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Cats; Cell Membrane; Concanavalin A; Female; Male; Methylmannosides; Nerve Degeneration; Nucleotidases; Schwann Cells; Sciatic Nerve; Uridine Diphosphate | 1985 |
Two mechanisms for inhibition of ADP-induced platelet shape change by 5'-p-fluorosulfonylbenzoyladenosine. Conversion to adenosine, and covalent modification at an ADP binding site distinct from that which inhibits adenylate cyclase.
Topics: Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenylyl Cyclase Inhibitors; Binding Sites; Blood Platelets; Cyclic AMP; Drug Synergism; Humans; Microscopy, Electron, Scanning; Thionucleotides | 1985 |
Adenosine analogues stimulate cyclic AMP formation in rabbit cerebral microvessels via adenosine A2-receptors.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Cats; Cerebral Cortex; Colforsin; Cyclic AMP; Diterpenes; Microcirculation; Phenylisopropyladenosine; Pyrrolidinones; Rabbits; Receptors, Cell Surface; Receptors, Purinergic; Rolipram | 1985 |
Further evidence for involvement of adenosine-5'-triphosphate in non-adrenergic non-cholinergic relaxation of the isolated rat duodenum.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Autonomic Nervous System; Chymotrypsin; Duodenum; gamma-Aminobutyric Acid; Male; Muscle Relaxation; Muscle, Smooth; Potassium; Pyrophosphatases; Rats; Rats, Inbred Strains; Theophylline | 1985 |
Xanthine derivatives as antagonists at A1 and A2 adenosine receptors.
Topics: Adenosine; Adenosine Diphosphate; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Adipose Tissue; Animals; Blood Platelets; Brain Chemistry; Cattle; Cell Membrane; Humans; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Xanthines | 1985 |
Dual inhibitory action of ATP on adrenergic neuroeffector transmission in rabbit pulmonary artery.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Dinoprostone; Electric Stimulation; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle, Smooth, Vascular; Neuroeffector Junction; Norepinephrine; Prostaglandins E; Pulmonary Artery; Rabbits; Sympathetic Nervous System; Synaptic Transmission | 1985 |
Activities and some properties of 5'nucleotidase in isolated hamster fat cells.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adipose Tissue; Animals; Cricetinae; Kinetics; Male; Mesocricetus; Nucleotidases | 1985 |
Platelet ADP receptor and alpha 2-adrenoreceptor interaction. Evidence for an ADP requirement for epinephrine-induced platelet activation and an influence of epinephrine on ADP binding.
Topics: Adenosine; Adenosine Diphosphate; Affinity Labels; Blood Platelets; Epinephrine; Humans; Kinetics; Platelet Aggregation; Receptors, Adrenergic, beta; Receptors, Cell Surface; Receptors, Purinergic | 1986 |
Adenosine production and release by adult rat cardiocytes.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Biological Transport, Active; Dinitrophenols; Dipyridamole; Heart; In Vitro Techniques; Iodoacetates; Iodoacetic Acid; Myocardium; Nucleotidases; Rats; Rats, Inbred Strains; Thioinosine | 1986 |
Binding of 3',4'-dideoxykanamycin B to ATP and its related compounds.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Chromatography, Affinity; Chromatography, Gel; Cyclic AMP; Dibekacin; Humans; In Vitro Techniques; Kanamycin; Kidney Diseases; Kidney Tubules, Proximal; Spectrometry, Fluorescence | 1986 |
Regulation of deoxyadenosine and nucleoside analog phosphorylation by human placental adenosine kinase.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Kinase; Adenosine Monophosphate; Adenosine Triphosphate; Deoxyadenosines; Female; Guanosine Triphosphate; Humans; Hydrogen-Ion Concentration; Kinetics; Nucleosides; Phosphotransferases; Placenta; Pregnancy; Substrate Specificity; Vidarabine | 1986 |
Mechanism of adenosine production by isolated rat heart mitochondria.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Biological Transport; In Vitro Techniques; Male; Mitochondria, Heart; Nucleotidases; Rats; Rats, Inbred Strains | 1986 |
The hydrolysis of extracellular adenine nucleotides by cultured endothelial cells from pig aorta. Feed-forward inhibition of adenosine production at the cell surface.
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Aorta; Cells, Cultured; Endothelium; Hydrolysis; Kinetics; Nucleotidases; Swine | 1986 |
The influence of inhibitors of the ATP degradative pathway on recovery of function and high energy phosphate after transient ischemia in the rat heart.
Topics: 5'-Nucleotidase; Acute Disease; Adenine; Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Triphosphate; Adenylate Kinase; Animals; Coronary Circulation; Coronary Disease; Dinucleoside Phosphates; Male; Nucleotidases; Rats; Rats, Inbred Strains; Thioinosine | 1986 |
ADP-induced platelet shape change and mobilization of cytoplasmic ionized calcium are mediated by distinct binding sites on platelets: 5'-p-fluorosulfonylbenzoyladenosine is a weak platelet agonist.
Topics: 4-Chloromercuribenzenesulfonate; Adenosine; Adenosine Diphosphate; Binding Sites; Blood Platelets; Calcium; Cyclic AMP; Cytoplasm; Humans; Osmolar Concentration | 1987 |
Direct evidence for the interaction of the nucleotide affinity analog 5'-p-fluorosulfonylbenzoyl adenosine with a platelet ADP receptor.
Topics: Adenosine; Adenosine Diphosphate; Blood Platelets; Humans; Membrane Proteins; Myosins; Osmolar Concentration; Phosphorylation; Receptors, Cell Surface | 1987 |
P1-purinoceptors in the cerebrovascular bed of the goat in vivo.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Blood Pressure; Carbon Dioxide; Cerebrovascular Circulation; Female; Goats; Heart Rate; Muscle Tonus; Oxygen Consumption; Receptors, Purinergic; Theophylline; Vasodilation | 1988 |
Gastric motor responses elicited by vagal stimulation and purine compounds in the atropine-treated rabbit.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Atropine; Blood Pressure; Electric Stimulation; Female; Gastrointestinal Motility; Purines; Rabbits; Theophylline; Triazines; Vagus Nerve | 1988 |
Extracellular nucleotide catabolism in human B and T lymphocytes. The source of adenosine production.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; B-Lymphocytes; Carbon Radioisotopes; Cell Line; Cells, Cultured; Humans; Hypoxanthine; Hypoxanthines; Inosine; Kinetics; Nucleotides; Palatine Tonsil; T-Lymphocytes; Tritium | 1988 |
Adenosine induction of rapid catabolism of adenine ribonucleotides and independent elevation of the ATP content in quiescent mouse fibroblasts.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cell Line; Coformycin; Deoxyadenosines; Guanosine Triphosphate; Inosine Monophosphate; Interphase; Kinetics; Mice | 1988 |
Adenosine stimulates glucose uptake in the isolated rat heart.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Chromatography, High Pressure Liquid; Glucose; Heart; In Vitro Techniques; Insulin; Male; Myocardium; Nitroprusside; Rats; Rats, Inbred Strains; Stimulation, Chemical; Time Factors | 1988 |
Distinction between glycoprotein IIIa and the 100-kDa membrane protein (aggregin) mediating ADP-induced platelet activation.
Topics: Adenosine; Adenosine Diphosphate; Animals; Electrophoresis, Polyacrylamide Gel; Female; Humans; Immunosorbent Techniques; Molecular Weight; Platelet Aggregation; Platelet Membrane Glycoproteins; Rabbits; Receptors, Purinergic | 1988 |
Influence of 2-chloroadenosine on the nucleotide content of isolated rat hepatocytes.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Diphosphate; Adenosine Kinase; Adenosine Triphosphate; Animals; Chromatography, High Pressure Liquid; Kinetics; Liver; Male; Nucleotides; Phosphorylation; Piperazines; Rats; Rats, Inbred Strains; Spectrophotometry; Tubercidin | 1988 |
Adenine nucleotide metabolites are beneficial for recovery of cardiac contractile force after hypoxia.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Female; Hypoxanthines; Hypoxia; Inosine; Male; Myocardial Contraction; Myocardium; Phosphocreatine; Rabbits | 1988 |
Energy metabolism in adenosine deaminase-inhibited human erythrocytes.
Topics: Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Triphosphate; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; Energy Metabolism; Erythrocytes; Glycolysis; Humans; Hypoxanthine; Hypoxanthines; Nucleoside Deaminases; Pentostatin; Ribonucleosides | 1986 |
Effect of insulin receptor autophosphorylation on insulin receptor binding.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cell Membrane; Female; Guanosine; Humans; Insulin; Male; Microsomes, Liver; Phosphorylation; Placenta; Pregnancy; Rats; Rats, Inbred Strains; Receptor, Insulin | 1986 |
Airway effects of purine nucleosides and nucleotides and release with bronchial provocation in asthma.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Asthma; Bronchi; Bronchial Provocation Tests; Forced Expiratory Volume; Histamine; Humans; Inosine; Kinetics; Methacholine Chloride; Methacholine Compounds | 1986 |
Evidence for an anti-aggregatory effect of adenosine at physiological concentrations and for its role in the action of dipyridamole.
Topics: Adenosine; Adenosine Diphosphate; Adult; Aged; Brain Ischemia; Dipyridamole; Female; Humans; In Vitro Techniques; Male; Middle Aged; Platelet Aggregation | 1987 |
Extracellular ATP modulates calcium uptake and transmitter release at the neuromuscular junction.
Topics: Acetylcholine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Astacoidea; Calcium; Electric Stimulation; Extracellular Space; Glucose; Neuromuscular Junction | 1987 |
Extracellular adenosine, inosine, hypoxanthine, and xanthine in relation to tissue nucleotides and purines in rat striatum during transient ischemia.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Brain Chemistry; Extracellular Space; Hypoxanthine; Hypoxanthines; Inosine; Ischemic Attack, Transient; Male; Nucleotides; Purines; Rats; Rats, Inbred Strains; Xanthine; Xanthines | 1987 |
[Metabolism of adenine nucleotides in thymocyte cytoplasm and subcellular fractions after treatment with concanavalin A, papaverine and adenosine].
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cells, Cultured; Concanavalin A; Cytoplasm; Papaverine; Rats; Rats, Inbred Strains; Subcellular Fractions; Thymus Gland | 1987 |
Separation of the 100-kDa membrane protein mediating ADP-induced platelet shape change and activation from glycoprotein IIIa.
Topics: Adenosine; Adenosine Diphosphate; Antibodies, Monoclonal; Blood Platelets; Humans; Immunochemistry; Molecular Weight; Platelet Membrane Glycoproteins; Receptors, Purinergic; Thrombasthenia | 1986 |
Biochemistry of an olfactory purinergic system: dephosphorylation of excitatory nucleotides and uptake of adenosine.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Axons; Chemoreceptor Cells; Hydrogen-Ion Concentration; Kinetics; Nephropidae; Olfactory Pathways; Phosphorylation; Purines; Sense Organs; Sodium; Tritium | 1987 |
Effect of dipyridamole on spontaneous platelet aggregation in whole blood decreases with the time after venepuncture: evidence for the role of ADP.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Diphosphate; Dipyridamole; Erythrocytes; Humans; In Vitro Techniques; Platelet Aggregation; Receptors, Purinergic | 1987 |
Phosphorylation potential and adenosine release during norepinephrine infusion in guinea pig heart.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Guinea Pigs; Heart; Hemodynamics; Magnetic Resonance Spectroscopy; Male; Myocardium; Norepinephrine; Phosphorylation; Reference Values | 1987 |
Mechanism of the antiplatelet action of dipyridamole in whole blood: modulation of adenosine concentration and activity.
Topics: Adenosine; Adenosine Diphosphate; Biological Transport, Active; Blood Platelets; Collagen; Dipyridamole; Erythrocytes; Female; Humans; In Vitro Techniques; Male; Morpholines; Platelet Aggregation; Xanthines | 1986 |
Inhibition of collagen-induced platelet activation by 5'-p-fluorosulfonylbenzoyl adenosine: evidence for an adenosine diphosphate requirement and synergistic influence of prostaglandin endoperoxides.
Topics: Adenosine; Adenosine Diphosphate; Collagen; Depression, Chemical; Drug Synergism; Humans; Indomethacin; Kinetics; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H | 1986 |
Inferences on the rapid metabolism of exogenously applied ATP in isolated smooth muscle preparations using pharmacological studies.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Guinea Pigs; In Vitro Techniques; Intestines; Muscle Relaxation; Muscle, Smooth; Trachea | 1986 |
Effects of ATP-MgCl2 and adenosine-MgCl2 administration on intracellular ATP levels in the kidney.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; In Vitro Techniques; Inosine; Inosine Monophosphate; Kidney; Kinetics; Magnesium; Magnesium Chloride; Male; Perfusion; Rats | 1986 |
Role of cellular energy state and adenosine in the regulation of coronary flow during variation in contraction frequency in an isolated perfused heart.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Coronary Circulation; Energy Metabolism; Female; In Vitro Techniques; Myocardial Contraction; Myocardium; Oxidative Phosphorylation; Oxygen Consumption; Perfusion; Rats; Rats, Inbred Strains | 1986 |
Release of endogenous and radioactive purines from the rabbit retina.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Animals; Dipyridamole; Evoked Potentials; Female; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Male; Potassium; Purines; Rabbits; Retina; Tritium | 1986 |
Adenosine release into venous plasma during free flow exercise.
Topics: Adenosine; Adenosine Diphosphate; Animals; Chromatography, High Pressure Liquid; Dogs; Electric Stimulation; Isoproterenol; Male; Oxygen Consumption; Physical Exertion; Veins | 1986 |
[Characteristics of adenosine activity on adenine nucleotide metabolism of rat thymocytes].
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Biological Transport; Coformycin; Inosine; Inosine Monophosphate; Pentostatin; Rats; Rats, Inbred Strains; Thymus Gland | 1985 |
Nucleoside transport and metabolism in erythrocytes from the Yucatan miniature pig. Evidence that inosine functions as an in vivo energy substrate.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood Glucose; Energy Metabolism; Erythrocytes; Inosine; Kinetics; Male; Nucleosides; Swine; Swine, Miniature | 1985 |
[Effect of various adenine derivatives on gastric acid secretion in the isolated rat stomach].
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Atropine; Dose-Response Relationship, Drug; Drug Synergism; Ergotamine; Ergotamines; Female; Gastric Acid; Gastric Mucosa; Male; Propranolol; Rats; Rats, Inbred Strains; Stimulation, Chemical | 1985 |
The effects of adenosine, ATP and ADP on ventricular automaticity induced by a local injury in the isolated right ventricle of the rat.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Female; Heart Rate; Heart Ventricles; In Vitro Techniques; Male; Myocardial Contraction; Rats; Rats, Inbred Strains; Theophylline; Ventricular Function | 1986 |
Electrical responses of smooth muscle cells of the rabbit ear artery to adenosine triphosphate.
Topics: Action Potentials; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cocaine; Dose-Response Relationship, Drug; Ear, External; Female; In Vitro Techniques; Male; Membrane Potentials; Muscle, Smooth, Vascular; Phentolamine; Quinidine; Rabbits; Theophylline | 1985 |
Fluorometric determination of adenine nucleotides and adenosine by ion-paired, reverse-phase, high-performance liquid chromatography.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Kidney; Rats; Spectrometry, Fluorescence | 1985 |
Adenosine nucleotides, adenosine and adenine as angiogenesis factors.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Angiogenesis Inducing Agents; Animals; Aorta; Cells, Cultured; Chemotaxis; Endothelium; Growth Substances; Swine | 1985 |
Measurement of adenosine metabolites and metabolism in isolated tissue preparations.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Chromatography, High Pressure Liquid; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Vas Deferens | 1985 |
The mechanism of adenosine release from hypoxic rat liver cells.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Dipyridamole; Liver; Oxygen; Rats; Thioinosine | 1985 |
Purine nucleotides stimulate DNA synthesis in kidney epithelial cells in culture.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Autoradiography; Cell Count; Cells, Cultured; Chlorocebus aethiops; DNA Replication; Epithelium; Kidney | 1985 |
Adenosine and related nucleotides alter calcium uptake in depolarized synaptosomes of torpedo electric organ.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Electric Organ; In Vitro Techniques; Potassium; Synaptosomes; Torpedo | 1985 |
Adenosine uptake and metabolism to cyclic 3',5'-adenosine monophosphate by normal and hyperplastic dog prostate glands.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aminoisobutyric Acids; Animals; Carbon Isotopes; Culture Media; Culture Techniques; Cyclic AMP; Dogs; Glucose; Inulin; Male; Phosphates; Prostate; Prostatic Hyperplasia; Spectrophotometry; Tritium | 1972 |
Regulation of the adenosine cyclic 3',5'-monophosphate content of rat cerebral cortex: ontogenetic development of the responsiveness to catecholamines and adenosine.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Cyclases; Adrenergic alpha-Antagonists; Aging; Animals; Animals, Newborn; Carbon Radioisotopes; Catecholamines; Cerebral Cortex; Cyclic AMP; Drug Synergism; Female; In Vitro Techniques; Isoproterenol; Male; Norepinephrine; Phentolamine; Pregnancy; Propranolol; Rats; Receptors, Adrenergic | 1973 |
Saccharopine dehydrogenase. A kinetic study of coenzyme binding.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Binding Sites; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Electrophoresis, Paper; Glyceric Acids; Guanine; Hypoxanthines; Kinetics; Lysine; Mathematics; NAD; NADP; Nucleoside Diphosphate Sugars; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Protein Binding; Ribonucleotides; Ribose; Saccharomyces cerevisiae; Ultrafiltration | 1974 |
Actions of putative transmitters in the chicken vagus nerve/oesophagus and Remak nerve/rectum preparations.
Topics: Adenosine; Adenosine Diphosphate; Animals; Animals, Newborn; Chickens; Cyclic AMP; Electric Stimulation; Esophagus; Histamine; In Vitro Techniques; Indomethacin; Methysergide; Muscle Contraction; Neural Conduction; Neurotransmitter Agents; Norepinephrine; Phentolamine; Polyphloretin Phosphate; Propranolol; Prostaglandin Antagonists; Prostaglandins; Pyrilamine; Rectum; Scopolamine; Serotonin; Synaptic Transmission; Vagus Nerve | 1974 |
Adenine nucleotide metabolism of blood platelets. 8. Transport of adenine into human platelets.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Antimetabolites; Antimycin A; Biological Transport, Active; Blood Platelets; Cyclic N-Oxides; Edetic Acid; Electrophoresis, Paper; Erythrocytes; Glucose; Humans; Hydrogen-Ion Concentration; Hypoxanthines; Kinetics; Papaverine; Prostaglandins; Time Factors; Tritium | 1973 |
Avian thrombocyte aggregation and shape change in vitro.
Topics: Adenosine; Adenosine Diphosphate; Animals; Blood Coagulation; Blood Platelets; Calcium; Chickens; Edetic Acid; Heparin; In Vitro Techniques; Male; Microscopy, Phase-Contrast; Physical Stimulation; Platelet Adhesiveness | 1973 |
Defective ristocetin-induced platelet aggregation in von Willebrand's disease and its correction by factor VIII.
Topics: Adenosine; Adenosine Diphosphate; Antibodies; Blood Coagulation Tests; Blood Platelet Disorders; Blood Platelets; Carbon Radioisotopes; Chromatography; Collagen; Cyanides; Edetic Acid; Factor VIII; Female; Glucose; Hemophilia A; Heparin; Humans; In Vitro Techniques; Male; Platelet Adhesiveness; Purpura, Thrombocytopenic; Ristocetin; Serotonin; von Willebrand Diseases | 1973 |
Bovine fibrinogen-induced platelet factor 3 and acid phosphatase availability in human platelets.
Topics: Acid Phosphatase; Adenosine; Adenosine Diphosphate; Animals; Blood Platelets; Cattle; Dose-Response Relationship, Drug; Edetic Acid; Fibrinogen; Humans; Platelet Adhesiveness; Stimulation, Chemical; Thromboplastin; Time Factors | 1973 |
Arachidonic acid-induced human platelet aggregation and prostaglandin formation.
Topics: Adenosine; Adenosine Diphosphate; Animals; Arachidonic Acids; Aspirin; Blood Platelets; Carbon Radioisotopes; Chromatography, Thin Layer; Collagen; Depression, Chemical; Dose-Response Relationship, Drug; Epinephrine; Guinea Pigs; Humans; Hydrogen-Ion Concentration; Naphthols; Photometry; Platelet Adhesiveness; Prostaglandin Antagonists; Prostaglandins; Rabbits; Radioimmunoassay; Stimulation, Chemical | 1973 |
Thrombocytopenia in experimental trypanosomiasis.
Topics: Adenosine; Adenosine Diphosphate; Animals; Blood Cell Count; Blood Platelets; Chymotrypsin; Complement System Proteins; Disseminated Intravascular Coagulation; Edetic Acid; Fibrin; Fibrinogen; Hematocrit; Humans; In Vitro Techniques; Male; Microscopy, Electron; Platelet Adhesiveness; Rabbits; Rats; Thrombocytopenia; Trypanosomiasis; Trypsin; Trypsin Inhibitors | 1974 |
AMP-aminohydrolase of human skeletal muscle: partial purification and properties.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aminohydrolases; Ammonia; Animals; Cations, Divalent; Cations, Monovalent; Edetic Acid; Fluorides; Humans; Hydrogen-Ion Concentration; Male; Muscles; Nucleotides; Organophosphorus Compounds; Phosphates; Potassium Chloride; Rabbits; Rats | 1974 |
Biosynthetic activities in normal and pathological platelet populations.
Topics: Adenosine; Adenosine Diphosphate; Blood Platelet Disorders; Blood Platelets; Blood Proteins; Cell Survival; Centrifugation, Density Gradient; Epinephrine; Glutamates; Glycogen; Glycogen Synthase; Histocompatibility Antigens; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lysine; Platelet Adhesiveness; Prostaglandins; Purpura, Thrombocytopenic; Thrombin; Thrombocytopenia | 1972 |
The effect of molecular iodine on platelet aggregation in vitro.
Topics: Adenosine; Adenosine Diphosphate; Animals; Collagen; Edetic Acid; Ethylmaleimide; Glutathione; Iodine; Platelet Adhesiveness; Rabbits | 1974 |
Primary platelet aggregation. Energy metabolism and the effect of inhibitors.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Antimetabolites; Blood Platelets; Chloromercuribenzoates; Colchicine; Cyanides; Edetic Acid; Epinephrine; Humans; Hydrochloric Acid; Hydrogen-Ion Concentration; Inosine Nucleotides; Lidocaine; Mercury; Organometallic Compounds; Platelet Adhesiveness; Platelet Aggregation; Prostaglandins; Serotonin; Sulfonic Acids; Time Factors; Tosyl Compounds; Tritium; Vasopressins | 1974 |
Purine metabolism in Neisseria meningitidis. 2. Utilization of exogenous adenosine, guanosine and inosine.
Topics: Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Kinase; Adenosine Monophosphate; Adenosine Triphosphate; Guanosine; Inosine; N-Glycosyl Hydrolases; Neisseria meningitidis; Purine-Nucleoside Phosphorylase | 1974 |
Platelet disaggregation and refractoriness to ADP.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Aminohydrolases; Blood Coagulation; Blood Platelets; Carbon Isotopes; Platelet Adhesiveness; Sodium Chloride; Spectrum Analysis; Time Factors | 1971 |
A "transport theory" for inhibition of platelet aggregation by adenosine.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Aminohydrolases; Biological Transport; Blood Platelets; Carbon Isotopes; Cell Aggregation; Cell Membrane Permeability; Dipyridamole; Papaverine | 1971 |
[Studies on platelet adhesiveness. I. The effects of various drugs in vitro].
Topics: Adenosine; Adenosine Diphosphate; Dipyridamole; Fibrinolysin; Fibrinolytic Agents; Glucose; Hematocrit; Hemolysis; Humans; In Vitro Techniques; Methods; Platelet Adhesiveness; Streptokinase | 1970 |
[Isolation and substrate specificity of a 3'-phosphoadenyl sulfate: chondroitin 6-sulfotransferase from mouse liver].
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Ammonium Sulfate; Animals; Cattle; Chemical Precipitation; Chloromercuribenzoates; Chondroitin; Chromatography, DEAE-Cellulose; Female; Galactose; Glucosamine; Glycosaminoglycans; Heparin; Hyaluronic Acid; Hydro-Lyases; Liver; Male; Mice; Phenols; Phosphates; Structure-Activity Relationship; Sulfates; Sulfur Isotopes; Sulfurtransferases | 1972 |
Human platelet clumping by bovine fibrinogen.
Topics: Adenosine; Adenosine Diphosphate; Afibrinogenemia; Animals; Aspirin; Blood Platelets; Cattle; Chromatography, Gel; Depression, Chemical; Edetic Acid; Fibrinogen; Fibrinolysin; Hot Temperature; Humans; Male; Plasma; Platelet Adhesiveness | 1972 |
Effect of dipyridamol on the electrokinetic potential of platelets.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphatases; Binding Sites; Blood Platelets; Cell Membrane; Dipyridamole; Humans; Kinetics; Platelet Aggregation; Time Factors | 1974 |
Interaction between adenine nucleotides and 3-phosphoglyceraldehyde dehydrogenase. I. Inhibition of the hydrolysis of S-acetyl-enzyme intermediate in the esterase activity.
Topics: Acetates; Acylation; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Chemical Phenomena; Chemistry; Cyclic AMP; Depression, Chemical; Diphosphates; Enzyme Activation; Glyceraldehyde-3-Phosphate Dehydrogenases; Guanine Nucleotides; Guanosine Triphosphate; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Light; Models, Biological; Muscles; NAD; Niacinamide; Nitrophenols; Nucleoside Diphosphate Sugars; Rabbits; Radiation Effects; Ribose; Spectrophotometry; Stimulation, Chemical | 1971 |
Interaction between adenine nucleotides and 3-phosphoglyceraldehyde dehydrogenase. II. A study of the mechanism of catalysis and metabolic control of the multi-functional enzyme.
Topics: Acetates; Acylation; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Arsenic; Autoradiography; Binding Sites; Carbon Isotopes; Catalysis; Chemical Phenomena; Chemistry; Cyclic AMP; Depression, Chemical; Diphosphates; Electrophoresis; Enzyme Activation; Glyceraldehyde-3-Phosphate Dehydrogenases; Guanine Nucleotides; Hydrogen-Ion Concentration; Hydrolysis; Muscles; NAD; Niacinamide; Nitrophenols; Nucleoside Diphosphate Sugars; Pepsin A; Peptides; Phosphoric Acids; Protein Binding; Rabbits; Ribose; Stimulation, Chemical | 1971 |
Gold (III) complexes of adenine nucleotides.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Buffers; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography; Chromatography, Gel; Chromatography, Thin Layer; Cyclic AMP; Deoxyadenosines; Ethanol; Gold; Hydrogen-Ion Concentration; Mathematics; Models, Structural; Phosphoric Acids; Polymers; Potassium; Solubility; Spectrophotometry; Thallium; Time Factors; Ultracentrifugation; Ultraviolet Rays | 1971 |
Adenyl cyclase activity in cultivated human skin fibroblasts.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenylyl Cyclases; Adrenocorticotropic Hormone; Carbon Isotopes; Cells, Cultured; Chromatography, Paper; Cyclic AMP; Enzyme Activation; Epinephrine; Fibroblasts; Fluorides; Glucagon; Humans; Isoproterenol; Norepinephrine; Skin; Sodium; Tritium; Vasopressins | 1971 |
Formation and metabolism of cyclic AMP in the mammalian central nervous system.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Animals; Biogenic Amines; Brain; Cerebellum; Cerebral Cortex; Cyclic AMP; Electric Stimulation; Guinea Pigs; Histamine; In Vitro Techniques; Magnesium; Mice; Norepinephrine; Potassium; Rabbits; Rats; Theophylline | 1971 |
Studies on the partial reactions catalyzed by the (Na++K+)-activated ATPase. 3. Relation of K+-dependent p-nitrophenylphosphatase to Na+ transport in red cell ghosts.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Biological Transport; Cell Membrane; Cesium; Chlorides; Cytosine Nucleotides; Enzyme Activation; Erythrocytes; Humans; Inosine Nucleotides; Kinetics; Lithium; Nitrophenols; Oligomycins; Ouabain; Phosphates; Phosphoric Acids; Phosphoric Monoester Hydrolases; Potassium Chloride; Rubidium; Sodium; Sodium Chloride; Sodium Isotopes; Stimulation, Chemical | 1971 |
Inhibition of marrow growth by cyclic AMP.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aminophylline; Animals; Bone Marrow; Bone Marrow Cells; Cell Differentiation; Cell Division; Cells, Cultured; Cyclic AMP; Drug Interactions; Epinephrine; Imidazoles; Insulin; Mice; Mice, Inbred Strains; Nicotinic Acids | 1971 |
The effect of aggregating agents on oxidative metabolism of rabbit platelets.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Animals; Antimycin A; Blood Platelets; Carbon Dioxide; Carbon Isotopes; Citric Acid Cycle; Cyclic AMP; Dinitrophenols; Glucose; In Vitro Techniques; Lysine; Oligomycins; Oxidative Phosphorylation; Peptides; Platelet Adhesiveness; Prostaglandins; Rabbits; Stimulation, Chemical; Thrombin | 1971 |
Cyclic AMP-stimulated protein kinase prepared from bovine thyroid glands.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Caseins; Cattle; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Cobalt; Cyclic AMP; Cyclic GMP; Cytosine Nucleotides; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Guanine Nucleotides; Guanosine; Histones; Hydrogen-Ion Concentration; In Vitro Techniques; Isoleucine; Magnesium; Manganese; Nucleotides; Phosphorus Isotopes; Phosphotransferases; Protamines; Proteins; Serum Albumin, Bovine; Thyroid Gland; Uracil Nucleotides | 1972 |
Bull semen nicotinamide adenine dinucleotide nucleosidase. 3. Properties of the substrate binding site.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Alkylation; Animals; Binding Sites; Cattle; Hydrogen-Ion Concentration; Kinetics; Male; Mathematics; N-Glycosyl Hydrolases; NAD; Niacinamide; Nucleoside Diphosphate Sugars; Protein Binding; Ribose; Semen; Structure-Activity Relationship | 1972 |
Reaction of 2-bromoacetamide-4-nitrophenol with heavy meromyosin ATPase.
Topics: Acetamides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Binding Sites; Bromine; Calcium; Chemical Phenomena; Chemistry; Diphosphates; Enzyme Activation; Hydrogen-Ion Concentration; Kinetics; Muscle Proteins; Muscles; Myosin Subfragments; Nitrophenols; Protein Binding; Spectrophotometry; Sulfhydryl Compounds; Time Factors | 1972 |
Inhibition of the protein kinase by adenine compounds: competitive inhibition with respect to ATP.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Ammonium Sulfate; Animals; Chemical Precipitation; Chromatography, DEAE-Cellulose; Cyclic AMP; Enzyme Activation; Histones; Kinetics; Liver; Male; Phosphorus Isotopes; Phosphotransferases; Proteins; Rats | 1972 |
Phenylalanyl transfer ribonucleic acid synthetase from Escherichia coli. Analysis of the adenosine triphosphate binding site.
Topics: Acylation; Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Alcohols; Amino Acyl-tRNA Synthetases; Binding Sites; Cyclohexanes; Deoxyadenosines; Diphosphates; Escherichia coli; Organophosphonates; Phosphoric Acids; Phosphorus Isotopes; Protein Binding; Purines; Structure-Activity Relationship; Thermodynamics | 1971 |
Inhibition of yeast inorganic pyrophosphatase by nucleotidylsulfates.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Cyclic AMP; Deoxyribonucleotides; Guanine Nucleotides; Guanosine Triphosphate; Inosine Nucleotides; Kinetics; Nucleotides; Pyrophosphatases; Sulfates; Yeasts | 1971 |
[Effect of S-adenosylmethionine (SAM) on platelet aggregation. In vitro and in vivo study].
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Blood Coagulation; Blood Platelets; Collagen; Cyclic AMP; Humans; In Vitro Techniques; Methionine; Platelet Adhesiveness; S-Adenosylmethionine; Serotonin | 1972 |
Inactivation of yeast alcohol dehydrogenase by dehydroascorbic acid and D-arabinosone.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Alcohol Oxidoreductases; Arabinose; Ascorbic Acid; Chloromercuribenzoates; Depression, Chemical; Glutathione; Ketones; Mercaptoethanol; NAD; Niacinamide; Ozone; Saccharomyces | 1972 |
I-Anilino-8-naphthalene sulfonate as a coenzyme-competitive inhibitor of yeast glyceraldehyde-3-phosphate dehydrogenase: multiple inhibition studies.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Aniline Compounds; Binding Sites; Coloring Agents; Fluorescence; Glyceraldehyde-3-Phosphate Dehydrogenases; NAD; Naphthalenes; Phosphates; Protein Binding; Protein Conformation; Saccharomyces cerevisiae; Spectrometry, Fluorescence; Structure-Activity Relationship; Sulfonic Acids | 1972 |
Fluorescent modification of adenosine-containing coenzymes. Biological activities and spectroscopic properties.
Topics: Acetaldehyde; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Allosteric Regulation; Chemical Phenomena; Chemistry; Chlorine; Coenzymes; Cyclic AMP; Cytidine; Fluorescence; Hexokinase; Mevalonic Acid; NAD; Nucleosides; Phosphofructokinase-1; Phosphotransferases; Pyruvate Kinase; Spectrometry, Fluorescence; Spectrophotometry; Structure-Activity Relationship; Ultraviolet Rays | 1972 |
Sequence studies of poliovirus RNA. I. Characterization of the 5'-terminus.
Topics: Adenosine; Adenosine Diphosphate; Alkaline Phosphatase; Base Sequence; Chromatography, DEAE-Cellulose; Chromatography, Thin Layer; Electrophoresis; Hydrolysis; Phosphorus Isotopes; Poliovirus; RNA, Viral | 1972 |
ADP as the cause of reversible inhibition of platelet retention in glass-bead columns.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adult; Blood Platelets; Chromatography; Glass; Hemoglobins; Hemolysis; Humans; Kinetics; Phosphoric Monoester Hydrolases; Platelet Adhesiveness | 1972 |
Blood nucleoside and nucleotide studies in mental disease.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adjustment Disorders; Adult; Bipolar Disorder; Chromatography, Thin Layer; Cyclic AMP; Erythrocytes; Female; Humans; Hydrolysis; Male; Mental Disorders; Middle Aged; NAD; Neurotic Disorders; Schizophrenia; Uridine Diphosphate Sugars | 1972 |
Cyclic 3',5'-adenosine monophosphate in human blood platelets. IV. Regulatory role of cyclic amp in platelet function.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Blood Platelets; Butyrates; Carbon Isotopes; Chromatography, Paper; Cyclic AMP; Humans; Platelet Adhesiveness; Prostaglandins; Protein Binding; Tritium | 1972 |
The effect of pyrimidine compounds on the potentiation of adenosine inhibition of aggregation, on adenosine phosphorylation and phosphodiesterase activity of blood platelets.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Blood Platelets; Carbon Isotopes; Cyclic AMP; Dipyridamole; Ethanolamines; Ethylamines; Humans; In Vitro Techniques; Morpholines; Phosphoric Diester Hydrolases; Piperidines; Platelet Adhesiveness; Pyrimidines; Thiophenes | 1973 |
A comparison of the effects of adenosine triphosphate with noradrenaline and with the inhibitory potential of the guinea-pig taenia coli.
Topics: Action Potentials; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Chlorides; Colon; Depression, Chemical; Dopamine; Female; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Muscle, Smooth; Norepinephrine; Phentolamine; Synaptic Transmission | 1973 |
Influence of cyclization and acyl substitution on the inotropic effects of adenine nucleotides.
Topics: Acylation; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Butyrates; Cyclic AMP; Cyclization; Female; Heart; Rats; Structure-Activity Relationship; Time Factors | 1973 |
Bull semen nicotinamide adenine dinucleotide nucleosidase. IV. Nonpolar interactions of inhibitors with the substrate binding site.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Alkanes; Animals; Binding Sites; Binding, Competitive; Carboxylic Acids; Cattle; Kinetics; Male; N-Glycosyl Hydrolases; NAD; Niacinamide; Phosphoric Acids; Protein Binding; Semen; Structure-Activity Relationship | 1972 |
The effect of adenosine and adenine nucleotides on the cyclic adenosine 3', 5'-phosphate content of guinea pig cerebral cortex slices.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Brain; Brain Chemistry; Cerebral Cortex; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; In Vitro Techniques; Kidney; Kinetics; Liver; Muscles; Perfusion; Structure-Activity Relationship; Tissue Extracts; Xanthines | 1970 |
Effect of repeated treatment of rabbit platelets with low concentrations of thrombin on their function, metabolism and survival.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Animals; Blood Platelets; Calcium; Cell Survival; Glucose; In Vitro Techniques; L-Lactate Dehydrogenase; Lactates; Magnesium; Microscopy, Electron; Phosphoric Monoester Hydrolases; Phosphorus Radioisotopes; Platelet Adhesiveness; Prostaglandins; Rabbits; Serotonin; Thrombin; Tritium | 1973 |
The lysosomal system in lymphocytes--from cyclic AMP to gene activation.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Bucladesine; Carbon Radioisotopes; Cell Nucleus; Cyclic AMP; DNA-Directed RNA Polymerases; Genes; Humans; Hydrolases; In Vitro Techniques; Lectins; Lymphocyte Activation; Lymphocytes; Lysosomes; Templates, Genetic; Theophylline; Trypsin | 1971 |
Promotion of conidia aggregation in Aspergillus niger by cyclic AMP and 5'-GMP.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aspergillus; Bucladesine; Cell Aggregation; Cell Division; Cyclic AMP; Cyclic GMP; Guanine Nucleotides; Guanosine; Theophylline | 1973 |
Conformation of coenzyme fragments when bound to lactate dehydrogenase.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Binding Sites; Crystallography; Electrons; Hydrogen-Ion Concentration; Isoenzymes; L-Lactate Dehydrogenase; Models, Structural; Molecular Conformation; NAD; Oxidation-Reduction; Protein Binding; Protein Conformation; Pyruvates; Sharks | 1973 |
Orthophosphate analysis by the Fiske-SubbaRow method and interference by adenosine phosphates and pyrophosphate at variable acid pH.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Bacteria; Diphosphates; Hydrogen-Ion Concentration; Methods; Molybdenum; Osmolar Concentration; Phosphates; Quaternary Ammonium Compounds | 1973 |
Antagonism of morphine analgesia by adenine, adenosine, and adenine nucleotides.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Analgesics; Animals; Cyclic AMP; Cytidine; Deoxyadenosines; Hypoxanthines; Male; Methods; Mice; Morphine; Structure-Activity Relationship; Uridine | 1973 |
Adenosine metabolism: properties of dog heart microsomal 5'-nucleotidase.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Carbon Radioisotopes; Centrifugation, Density Gradient; Cobalt; Cyclic AMP; Dogs; Guanine Nucleotides; Hydrolysis; Magnesium; Manganese; Methane; Microsomes; Myocardium; Nucleotidases; Phospholipases; Sucrose; Uracil Nucleotides | 1973 |
Specificity of nucleotide-induced insulin secretion.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cricetinae; Cyclic AMP; Cytosine Nucleotides; Glucose; Guanosine Triphosphate; Inosine Nucleotides; Insulin; Insulin Secretion; Male; Pancreas; Phosphates; Phosphocreatine; Sodium; Uracil Nucleotides; Uridine | 1974 |
Induction of delta-aminolevulinic acid synthetase in isolated rat liver cell suspensions. Adenosine 3':5'-monophosphate dependence of induction by drugs.
Topics: 5-Aminolevulinate Synthetase; Acetamides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Allylisopropylacetamide; Animals; Bucladesine; Cyclic AMP; Cyclic GMP; Cycloheximide; Dactinomycin; Dicarboxylic Acids; Drug Synergism; Enzyme Induction; Fasting; Hydrocortisone; In Vitro Techniques; Kinetics; Liver; Male; Pyridines; Rats; RNA; Time Factors | 1974 |
Interactions of the pharmacological receptors of blood platelets with adenylate cyclase.
Topics: Adenosine; Adenosine Diphosphate; Adenylyl Cyclases; Binding Sites; Blood Platelets; Caffeine; Carbon Radioisotopes; Centrifugation, Density Gradient; Chromatography, Thin Layer; Cyclic AMP; Enzyme Activation; Epinephrine; Humans; Isoproterenol; Papaverine; Platelet Adhesiveness; Prostaglandins; Receptors, Adrenergic; Stimulation, Chemical; Sympatholytics; Time Factors | 1973 |
Inhibition of platelet aggregation by isochinoline derivatives.
Topics: Adenosine; Adenosine Diphosphate; Blood Coagulation; Blood Platelets; Calcium; Collagen; Cyclic AMP; Depression, Chemical; Dose-Response Relationship, Drug; Glucose; Humans; In Vitro Techniques; Isoproterenol; Isoquinolines; Papaverine; Phosphoric Diester Hydrolases; Platelet Adhesiveness; Prostaglandins; Theophylline; Time Factors | 1972 |
(3H)-adenosine nucleotide and (3H)-noradrenaline uptake by cold stored guinea-pig taenia caecum; mechanical effects and release of (3H)-adenosine nucleotide by noradrenaline, papaverine, and nitroglycerine.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cecum; Cocaine; Cyclic AMP; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Male; Nicotine; Nitroglycerin; Norepinephrine; Oligomycins; Papaverine; Phenoxybenzamine; Phentolamine; Propranolol; Refrigeration; Tritium | 1973 |
Investigation of the release reaction in platelets exposed to phorbol myristate acetate.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Alcohols; Blood Platelets; Carbon Radioisotopes; Cytoplasmic Granules; Diterpenes; Edetic Acid; Epinephrine; Fatty Acids; Glycogen; Histocytochemistry; Humans; L-Lactate Dehydrogenase; Microscopy, Electron; Microtubules; Mitochondria; Organoids; Phosphoric Monoester Hydrolases; Platelet Adhesiveness; Prostaglandins; Pyruvate Kinase; Serotonin; Theophylline | 1974 |
Distribution of bound ADP-ribose derivatives in nuclear protein of rat liver nuclei.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Carbon Radioisotopes; Cell Nucleus; Chromatography, Ion Exchange; Chromatography, Thin Layer; Female; Hydroxylamines; Liver; Male; NAD; Nucleoproteins; Nucleoside Diphosphate Sugars; Oligonucleotides; Phosphoric Diester Hydrolases; Rats; Ribose; Snakes; Solubility; Venoms | 1974 |
Stimulation of prostaglandin biosynthesis by adenine nucleotides. Profile of prostaglandin release by perfused organs.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adipose Tissue; Angiotensin II; Animals; Biological Assay; Chickens; Epinephrine; Female; Indomethacin; Kidney; Liver; Lung; Myocardium; Perfusion; Prostaglandins; Rabbits; Rats; Spleen | 1974 |
Methods for the separation of platelets from plasma. A comparison of functional and morphological integrity.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Aspirin; Blood Coagulation Factors; Blood Platelets; Cell Separation; Centrifugation, Density Gradient; Chromatography, Gel; Collagen; Humans; Luminescent Measurements; Methods; Microscopy, Electron; Phosphoric Monoester Hydrolases; Platelet Adhesiveness; Prostaglandins; Serum Albumin, Bovine; Venoms | 1974 |
The influence of benzamidine derivatives on human platelet function.
Topics: Adenosine; Adenosine Diphosphate; Amidines; Aminobenzoates; Anilides; Blood Coagulation; Blood Coagulation Tests; Clot Retraction; Collagen; Fibrinogen; Humans; Methyl Ethers; Nitro Compounds; Phosphoric Diester Hydrolases; Platelet Adhesiveness; Serotonin; Thrombin | 1974 |
Maleimideinactivation of lactate dehydrogenase isozymes.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Binding Sites; Binding, Competitive; Isoenzymes; Kinetics; L-Lactate Dehydrogenase; Maleimides; Myocardium; NAD; Nucleoside Diphosphate Sugars; Oxidation-Reduction; Protein Binding; Ribose; Structure-Activity Relationship; Time Factors | 1974 |
Regulation of adenosine 3':5'-monophosphate content in human astrocytoma cells by adenosine and the adenine nucleotides.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Astrocytoma; Biological Transport; Carbon Radioisotopes; Cell Line; Chromatography, Ion Exchange; Chromatography, Paper; Clone Cells; Cyclic AMP; Humans; Kinetics; Norepinephrine; Papaverine; Phentolamine; Phosphoric Diester Hydrolases; Propranolol; Receptors, Drug; Theophylline; Time Factors; Tritium; Xanthines | 1974 |
Cyclic AMP as a cell surface activating agent in Dictyostelium discoideum.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Cell Membrane; Chromatography, Thin Layer; Cyclic AMP; Isotope Labeling; Kinetics; Myxomycetes; Phosphates; Phosphorus Radioisotopes; Time Factors; Tritium | 1974 |
Inhibition of platelet adherence to a collagen-coated surface by agents that inhibit platelet shape change and clot retraction.
Topics: Adenosine; Adenosine Diphosphate; Animals; Blood Platelets; Caffeine; Carbon Radioisotopes; Chromium Radioisotopes; Clot Retraction; Colchicine; Collagen; Cyclic AMP; Cytochalasin B; Maleimides; Mercuribenzoates; Phosphoric Monoester Hydrolases; Platelet Adhesiveness; Prostaglandins; Serotonin; Sulfhydryl Compounds; Sulfonic Acids; Swine | 1974 |
Effect of pharmacological agents on human keratinocyte mitosis in vitro. I. Inhibition by adenine nucleotides.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Bucladesine; Cells, Cultured; Cyclic AMP; Cyclic GMP; Cytidine; Cytosine Nucleotides; Depression, Chemical; Guanine; Guanine Nucleotides; Guanosine; Guanosine Triphosphate; Humans; Hypoxanthines; Inosine; Inosine Nucleotides; Mitosis; Skin; Thymine Nucleotides; Uracil Nucleotides | 1974 |
Purine nucleotide metabolism in the cat brain after one hour of complete ischemia.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Brain; Carbon Radioisotopes; Cats; Cerebrovascular Circulation; Chromatography, Ion Exchange; Formates; Guanine Nucleotides; Guanosine Triphosphate; Hypoxanthines; Inosine; Inosine Nucleotides; Ischemia; NAD; Pentosyltransferases; Phosphotransferases; Purine Nucleotides; Spectrophotometry, Ultraviolet; Time Factors; Tritium | 1974 |
Interrelationships among the levels of ATP, adenosine and cyclic AMP in incubated slices of guinea-pig cerebral cortex: effects of depolarizing agents, psychotropic drugs and metabolic inhibitors.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antimetabolites; Batrachotoxins; Carbon Radioisotopes; Cerebral Cortex; Chlorpromazine; Chromatography, Ion Exchange; Chromatography, Thin Layer; Clomipramine; Cyclic AMP; Dibenzazepines; Guinea Pigs; Histamine; In Vitro Techniques; Male; Norepinephrine; Ouabain; Potassium; Prenylamine; Serotonin; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Time Factors; Veratrine | 1974 |
Effect of cyclic AMP on nucleoside metabolism. III. Effect on uridine incorporation in monkey (CV-1) cells.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Bucladesine; Cell Line; Chromatography, Paper; Cyclic AMP; Haplorhini; Kidney; Kinetics; Phosphorus Radioisotopes; RNA; Solubility; Time Factors; Transcription, Genetic; Uridine | 1974 |
Purification and characterization of adenosine-adenosine cyclic 3',5'-monophosphate binding protein factors from rabbit erythrocytes.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Binding Sites; Carrier Proteins; Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Cyclic AMP; Electrophoresis, Disc; Erythrocytes; Kinetics; Molecular Weight; Phosphorus Radioisotopes; Protamines; Protein Binding; Protein Conformation; Protein Kinases; Rabbits; Receptors, Drug; Tritium; Urea | 1974 |
Modification by external calcium and magnesium ions of the potentiative action of 5'-AMP on the ATP-induced contraction of isolated guinea-pig ileum.
Topics: Acetylcholine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; Ileum; In Vitro Techniques; Magnesium; Muscle Contraction | 1974 |
Effects of cyclic AMP, sympathomimetic amines, and adrenergic receptor antagonists on renin secretion.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Arteries; Blood Pressure; Creatinine; Cyclic AMP; Dogs; Glomerular Filtration Rate; Heart Rate; Isoproterenol; Kidney; Lidocaine; Norepinephrine; Phentolamine; Propranolol; Regional Blood Flow; Renin; Sodium; Sympatholytics; Sympathomimetics; Urine | 1971 |
Carbon dioxide fixation by isolated chloroplasts of Egulena gracilis. II. Inhibition of CO 2 fixation by AMP.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Carbon Dioxide; Carbon Isotopes; Chloroplasts; Euglena gracilis; Light; NADP; Nucleotides; Pentosephosphates; Phosphotransferases; Photophosphorylation; Purines; Radiation Effects | 1972 |
Studies on adenine nucleotide exchange in mitochondria from the muscle tissue of Ascaris lumbricoides (Nematoda).
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Ascaris; Calcium; Carbon Radioisotopes; In Vitro Techniques; Isotope Labeling; Magnesium; Methods; Mitochondria, Muscle; Potassium; Swine; Temperature; Time Factors | 1974 |
Separation and determination of nanomole amounts of some purines, uric acid and uric acid riboside by two-dimensional paper chromatography.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Amino Acids; Chromatography, Paper; Hypoxanthines; Methods; Microchemistry; Nucleosides; Purines; Uric Acid; Xanthines | 1974 |
The inhibition of platelet aggregation by an aorta intima extract.
Topics: Achilles Tendon; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Aorta; Collagen; Endothelium; Epinephrine; Humans; Hypoxanthines; Inosine; Muscle, Smooth; Platelet Adhesiveness; Thrombin; Tissue Extracts | 1974 |
Measurement of the platelet response to laser-induced microvascular injury. Assessment of determinants of platelet aggregation in vivo.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Blood Flow Velocity; Blood Pressure; Blood Vessels; Lasers; Microcirculation; Platelet Adhesiveness; Rabbits | 1974 |
[The effect of methylxanthines on catecholamine and adenylate nucleotide concentration in rat myocardium].
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Caffeine; Inosine; Inosine Nucleotides; Myocardium; Phosphorus; Rats; Stimulation, Chemical; Strophanthins; Theobromine; Theophylline; Tyramine; Xanthines | 1974 |
Effects of dilazep on platelet aggregation.
Topics: Adenosine; Adenosine Diphosphate; Animals; Azepines; Benzoates; Blood Coagulation Tests; Collagen; Depression, Chemical; Dipyridamole; Dogs; Drug Interactions; Male; Platelet Adhesiveness; Platelet Aggregation; Rabbits; Thrombelastography; Vasodilator Agents | 1974 |
Adenosine inhibition of human platelet aggregation by ADP.
Topics: Adenosine; Adenosine Diphosphate; Blood Platelets; Buffers; Cell Aggregation; Drug Synergism; Humans; Hypoxanthines; Inosine; Time Factors | 1972 |
Regulation and mechanism of platelet aggregation.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Blood Platelets; Cell Membrane; Colchicine; Cold Temperature; Collagen; Ethylmaleimide; Glass; Humans; Iodoacetates; Lysine; Mercuribenzoates; Microscopy, Electron, Scanning; Platelet Adhesiveness; Thrombin | 1972 |
Studies on nucleotides and related compounds in plants. II. An adenyl-cleaving enzyme system in potato tubers.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Ammonium Sulfate; Deoxyadenosines; Freeze Drying; Hydrogen-Ion Concentration; Hydrolysis; N-Glycosyl Hydrolases; Nucleosides; Nucleotides; Plants; Structure-Activity Relationship; Temperature; Vegetables | 1972 |
A study of platelet retention by glass bead columns ('platelet adhesiveness' in normal subjects).
Topics: Adenosine; Adenosine Diphosphate; Blood Cell Count; Blood Platelets; Blood Specimen Collection; Glass; Humans; Methods; Platelet Adhesiveness; Uremia; von Willebrand Diseases | 1972 |
Alternative pathways of deoxyadenosine and adenosine metabolism.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aminohydrolases; Animals; Brain; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Deamination; Deoxyadenosines; Deoxyribonucleotides; Erythrocytes; Humans; Kidney; Liver; Male; Mice; Myocardium; Organ Specificity; Phosphoric Acids; Sheep; Species Specificity | 1973 |
Incorporation of nucleosides into the nucleotide pools of human erythrocytes. Adenosine and its analogs.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aminohydrolases; Antibiotics, Antineoplastic; Aza Compounds; Carbohydrate Metabolism; Deoxyadenosines; Erythrocytes; Fluorine; Humans; Inosine; Mercaptopurine; Nucleosides; Phosphotransferases; Pyrazoles; Pyrimidines; Pyrimidinones; Pyrroles; Ribonucleosides; Structure-Activity Relationship | 1973 |
A convenient assay for ADP reductase activity using Dowex-1-borate columns.
Topics: Adenosine; Adenosine Diphosphate; Animals; Boric Acids; Carbon Radioisotopes; Carcinoma, Ehrlich Tumor; Chromatography, Ion Exchange; Chromatography, Paper; Deoxyadenosines; Disposable Equipment; Evaluation Studies as Topic; Methods; Mice; Mice, Inbred Strains; Ribonucleotide Reductases; Spectrophotometry, Ultraviolet | 1973 |
Mode of action of some oxidized sugar derivatives of adenine on platelet aggregation.
Topics: Adenosine; Adenosine Diphosphate; Aldehydes; Blood Platelets; Cell Aggregation; Humans; Oxidation-Reduction; Structure-Activity Relationship | 1972 |
[Aggregation effectors and platelet populations].
Topics: Adenosine; Adenosine Diphosphate; Anticoagulants; Blood Platelets; Blood Preservation; Cell Aggregation; Centrifugation, Density Gradient; Dipyridamole; Epinephrine; Ethylmaleimide; Humans; Lithium | 1972 |
Phenylalanyl-tRNA synthetase from E. coli: synergistic coupling between the sites for binding of L-phenylalanine and ATP.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Amino Acyl-tRNA Synthetases; Binding Sites; Carbon Radioisotopes; Drug Synergism; Escherichia coli; Kinetics; Ligands; Phenylalanine; Phosphorus Radioisotopes; Protein Binding; Spectrometry, Fluorescence | 1973 |
Aggregation of blood platelets in some animal species.
Topics: Adenosine; Adenosine Diphosphate; Animals; Cattle; Chloromercuribenzoates; Collagen; Depression, Chemical; Dogs; Epinephrine; Humans; Microscopy, Phase-Contrast; Platelet Adhesiveness; Rabbits; Rats; Species Specificity; Stimulation, Chemical; Swine; Thrombin | 1972 |
On the mechanism of platelet aggregation induced by heparin, protamine and polybrene.
Topics: Adenosine; Adenosine Diphosphate; Aspirin; Blood Platelets; Cell Membrane; Edetic Acid; Heparin; Heparin Antagonists; In Vitro Techniques; Platelet Adhesiveness; Polymers; Protamines | 1972 |
A case of thrombasthenia with a study of platelet aggregation by hydrogen peroxide (H 2 O 2 ).
Topics: Adenosine; Adenosine Diphosphate; Adolescent; Adult; Blood Coagulation Tests; Blood Platelet Disorders; Blood Platelets; Child; Edetic Acid; Ethylmaleimide; Female; Glutathione; Hemorrhage; Humans; Hydrogen Peroxide; In Vitro Techniques; Purpura, Thrombocytopenic | 1972 |
Reversal of the rapid morphological reaction of platelets.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood Platelets; Edetic Acid; Microscopy, Electron; Prostaglandins; Rabbits | 1972 |
Effect of AMP and related compounds on glycogen content of Tetrahymena.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Anaerobiosis; Animals; Carbon Dioxide; Carbon Isotopes; Cell Count; Culture Media; Cytidine; Glycogen; Glyoxylates; Inosine; Lipid Metabolism; Tetrahymena pyriformis; Uridine | 1972 |
Isolation and identification of the platelet aggregation inhibitor present in the onion, Allium cepa.
Topics: Adenosine; Adenosine Diphosphate; Aminohydrolases; Chromatography, Gel; Chromatography, Thin Layer; Densitometry; Dialysis; Humans; Mass Spectrometry; Plants; Platelet Adhesiveness; Spectrophotometry, Ultraviolet; Ultrafiltration | 1972 |
A 13 C nuclear-magnetic-resonance study of the enzyme cofactor flavin-adenine dinucleotide.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Carbon Isotopes; Chemical Phenomena; Chemistry; Deuterium; Flavin-Adenine Dinucleotide; Fourier Analysis; Magnetic Resonance Spectroscopy; Riboflavin | 1972 |
Adenylate metabolism and adenosine formation in the heart.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Bile Acids and Salts; Cations, Divalent; Columbidae; Coronary Circulation; Dogs; Enzyme Activation; Histocytochemistry; Hydrolysis; In Vitro Techniques; Magnesium; Myocardium; Nucleotidases; Rabbits; Rats; Regional Blood Flow; Species Specificity; Turtles | 1972 |
Phosphorylation and deamination of adenosine by the isolated, perfused rat heart.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aminohydrolases; Animals; Carbon Isotopes; Chromatography, Gel; Chromatography, Thin Layer; Hypoxanthines; Inosine; Male; Models, Biological; Myocardium; Perfusion; Phosphotransferases; Rats; Time Factors | 1972 |
Inhibition of platelet aggregation by drugs.
Topics: Adenosine; Adenosine Diphosphate; Animals; Aspirin; Blood Cell Count; Blood Coagulation; Blood Platelets; Collagen; Densitometry; Depression, Chemical; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Injections, Intravenous; Methods; Muscle, Smooth; Papaverine; Phenylbutazone; Platelet Adhesiveness; Rabbits; Temperature; Thrombin; Vasodilator Agents | 1972 |
Effects of saturated and unsaturated fatty acids on blood platelet aggregation in vitro and after injection into rabbits.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood Cell Count; Blood Platelets; Collagen; Densitometry; Epinephrine; Fatty Acids; Fatty Acids, Unsaturated; Injections, Intravenous; Linolenic Acids; Platelet Adhesiveness; Rabbits; Serum Albumin; Structure-Activity Relationship; Thrombin; Thrombocytopenia; Time Factors | 1972 |
[The effect of the coronary dilator lidoflazine on myocardial adenosine metabolism in ischemia and anoxia].
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cell Membrane Permeability; Coronary Vessels; Dogs; Heart; Hypoxanthines; Hypoxia; Inosine; Ischemia; Lactates; Myocardium; Phosphocreatine; Piperazines; Vasodilator Agents | 1972 |
Biological activity of a semisynthetic flavonoid, O-( -hydroxyethyl)rutoside: light-scattering and metabolic studies of human red cells and platelets.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Binding Sites; Blood Circulation; Blood Platelets; Carbon Isotopes; Cell Aggregation; Cell Membrane; Diffusion; Dose-Response Relationship, Drug; Epinephrine; Erythrocytes; Ethanol; Humans; In Vitro Techniques; Light; Phosphoric Acids; Rutin; Scattering, Radiation; Temperature; Veins | 1973 |
The action of ATP in the guinea-pig heart.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Carbon Isotopes; Guinea Pigs; Heart; In Vitro Techniques; Inosine; Kinetics; Myocardium; Phosphorus Isotopes | 1973 |
Pathways of nucleotide metabolism in Schistosoma mansoni. IV. Incorporation of adenosine analogs in vitro.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Aza Compounds; Body Weight; Culture Media; Fluorine; Guanine Nucleotides; In Vitro Techniques; Mice; Mice, Inbred Strains; Nucleotides; Schistosoma mansoni; Time Factors; Tritium | 1973 |
Spectrophotometric evidence for the formation of a 2-nickel-adenosine triphosphate complex.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Chemical Phenomena; Chemistry; Fluorescence; Hydrogen-Ion Concentration; Ligands; Mathematics; Nickel; Osmolar Concentration; Protein Binding; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 1973 |
Platelet aggregation inhibitors. 4. N 6 -substituted adenosines.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Blood Platelets; Cell Aggregation; Chemical Phenomena; Chemistry; Collagen; Humans; Male; Platelet Adhesiveness; Rabbits; Structure-Activity Relationship; Time Factors | 1973 |
Nerve-mediated inhibition of mechanical activity in rabbit duodenum and the effects of desensitization to adenosine and several of its derivatives.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Atropine; Desensitization, Immunologic; Dose-Response Relationship, Drug; Duodenum; Electric Stimulation; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phentolamine; Phenylephrine; Propranolol; Rabbits; Reserpine; Structure-Activity Relationship; Tetrodotoxin | 1973 |
Aggregation of duck thrombocytes by 5-hydroxytryptamine.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Blood Platelets; Dose-Response Relationship, Drug; Ducks; Methysergide; Piperidines; Platelet Adhesiveness; Prostaglandins; Pyrimidines; Serotonin | 1973 |
The effect of dipyridamole and RA 233 on human platelet function in vitro.
Topics: Adenosine; Adenosine Diphosphate; Blood Platelets; Dipyridamole; Erythrocytes; Ethanolamines; Humans; Piperidines; Platelet Adhesiveness; Pyrimidines | 1973 |
Platelet aggregation inhibitors. 6. 2-Thioadenosine derivatives.
Topics: Adenosine; Adenosine Diphosphate; Animals; Chromatography, Paper; Collagen; Depression, Chemical; Dimethyl Sulfoxide; Hydrogen-Ion Concentration; In Vitro Techniques; Osmolar Concentration; Platelet Adhesiveness; Rabbits; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds; Sulfides; Thionucleosides | 1973 |
Adenosine metabolism in platelets and plasma.
Topics: Adenosine; Adenosine Diphosphate; Animals; Anticoagulants; Binding Sites; Blood Cell Count; Blood Platelets; Buffers; Carbon Radioisotopes; Centrifugation, Density Gradient; Depression, Chemical; Dipyridamole; Guinea Pigs; Humans; Hypoxanthines; Inosine; Lithium; Platelet Adhesiveness; Prostaglandins; Rabbits; Rats; Receptors, Drug; Species Specificity; Temperature; Time Factors; Uric Acid | 1973 |
The interaction of myosin, actin and ATP in the intact muscle.
Topics: Actins; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Anura; Binding Sites; Carbon Radioisotopes; Ethylmaleimide; Inosine; Inosine Nucleotides; Iodoacetates; Kinetics; Macromolecular Substances; Models, Biological; Muscle Contraction; Muscles; Myosins; Peptides; Protein Binding; Protein Conformation; Spectrophotometry, Ultraviolet; Time Factors | 1973 |
The measurement of intravascular aggregation by continuous platelet counting.
Topics: Adenosine; Adenosine Diphosphate; Animals; Aspirin; Blood Cell Count; Blood Platelets; Catheterization; Citrates; Dipyridamole; Dogs; Guinea Pigs; Methysergide; Platelet Adhesiveness; Prostaglandins; Rabbits; Serotonin; Serotonin Antagonists | 1973 |
Pyrimidine starvation induced by adenosine in fibroblasts and lymphoid cells: role of adenosine deaminase.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adolescent; Aminohydrolases; Animals; Cell Line; Cytosine Nucleotides; Female; Fibroblasts; Guanine Nucleotides; Guanosine Triphosphate; Humans; Infectious Mononucleosis; Lymphocytes; Lymphoma; Mice; Pyrimidine Nucleotides; Uracil Nucleotides; Uridine | 1973 |
Effect of 4,5-diphenyl-2-bis-(2-hydroxyethyl)aminoxazol (ditazol) on platelet aggregation, adhesiveness and bleeding time.
Topics: Adenosine; Adenosine Diphosphate; Adult; Analysis of Variance; Animals; Anti-Inflammatory Agents; Aspirin; Blood Coagulation; Collagen; Dipyridamole; Drug Interactions; Epinephrine; Ethanol; Ethanolamines; Humans; Male; Mice; Middle Aged; Oxazoles; Phenylbutazone; Platelet Adhesiveness; Rabbits; Time Factors | 1973 |
Inhibition of platelet-induced thrombus formation.
Topics: Adenosine; Adenosine Diphosphate; Aspirin; Blood Platelets; Brain Diseases; Dipyridamole; Epinephrine; Glomerulonephritis; Heart Valve Prosthesis; Humans; Hypertension, Malignant; Ischemia; Myocardial Infarction; Platelet Adhesiveness; Postoperative Complications; Prostaglandins; Pyrimidines; Thromboembolism; Thrombophlebitis; Thrombosis; Xanthines | 1974 |
An unusual pathway for the synthesis of adenosine triphosphate by the purine-requiring organism Artemia salina.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Carbon Radioisotopes; Decapoda; Guanine Nucleotides; Guanosine; Guanosine Triphosphate; Hydrogen-Ion Concentration; Larva; Models, Chemical; Purines; Ribose; Solubility | 1974 |
Effects of adenine nucleotides on contractility of normal and postischemic myocardium.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cats; Coronary Circulation; Dose-Response Relationship, Drug; Heart; Heart Ventricles; In Vitro Techniques; Ischemia; Papillary Muscles; Time Factors | 1974 |
Changes in energy state and acid-base parameters of the rat brain during complete compression ischemia.
Topics: Acid-Base Equilibrium; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Amino Acids; Ammonia; Animals; Aspartic Acid; Brain; Carbohydrate Metabolism; Carbon Dioxide; Citrates; Disease Models, Animal; Glucose; Glutamates; Glutamine; Hydrogen-Ion Concentration; Intracranial Pressure; Ischemic Attack, Transient; Ketoglutaric Acids; Lactates; Malates; Nucleotidases; Oxidation-Reduction; Partial Pressure; Phosphocreatine; Pyruvates; Rats | 1974 |
Cerebral metabolic state following complete compression ischemia.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Amino Acids; Ammonia; Animals; Aspartic Acid; Blood Pressure; Carbohydrate Metabolism; Carbon Dioxide; Cerebral Cortex; Citric Acid Cycle; Disease Models, Animal; Electroencephalography; Glucose; Glutamine; Hydrogen-Ion Concentration; Intracranial Pressure; Ischemic Attack, Transient; Ketoglutaric Acids; Lactates; Malates; Mitochondria; Nucleotidases; Oxygen; Partial Pressure; Phosphocreatine; Pyruvates; Rats; Time Factors | 1974 |
Inhibition of horse-liver alcohol dehydrogenase by Pt(CN)4 2- and Au(CN)2-.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Alcohol Oxidoreductases; Amino Acid Sequence; Animals; Arginine; Binding Sites; Cyanides; Gold; Horses; Iodoacetates; Kinetics; Liver; Nucleoside Diphosphate Sugars; Phenanthrolines; Platinum; Ribose | 1974 |
Studies on the shape change in rabbit platelets induced by adenosine diphosphate or several metabolic inhibitors.
Topics: Adenosine; Adenosine Diphosphate; Animals; Blood Platelets; Densitometry; Ethylmaleimide; Iodoacetates; Platelet Adhesiveness; Rabbits | 1974 |
A new method to determine sugar-base torsion in purine nucleosides and nucleotides.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Binding Sites; Bromine; Deuterium; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Manganese; Molecular Conformation; Ribose | 1974 |
Some evidence that ADP is not the only agent responsible for collagen-induced aggregation.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Blood Coagulation; Blood Platelets; Collagen; Edetic Acid; Promethazine; Prostaglandins; Sodium Chloride; Time Factors | 1971 |
Light scattering and platelet aggregation.
Topics: Adenosine; Adenosine Diphosphate; Blood Coagulation; Blood Coagulation Tests; Blood Platelets; Edetic Acid; Light; Scattering, Radiation; Sodium Chloride | 1971 |
In vivo modification of the energy charge in the liver cell.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Fatty Acids; Kinetics; Liver; Liver Glycogen; Male; Rats | 1972 |
Platelet aggregation inhibitors. 2. Inhibition of platelet aggregation by 5'-, 2-, 6-, and 8-substituted adenosines.
Topics: Adenosine; Adenosine Diphosphate; Animals; Depression, Chemical; Male; Oximes; Platelet Adhesiveness; Purines; Rabbits; Ribonucleosides; Structure-Activity Relationship; Sulfhydryl Compounds | 1972 |
The mechanism of adenosine diphosphate induced platelet aggregation: binding to platelet receptors and inhibition of binding and aggregation by prostaglandin E 1 .
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Binding Sites; Blood Platelets; Carbon Isotopes; Cell Membrane; Chromatography, Thin Layer; Humans; In Vitro Techniques; Platelet Adhesiveness; Prostaglandins | 1972 |
Myocardial reactive hyperemia: comparative effects of adenosine, ATP, ADP, and AMP.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Coronary Circulation; Dogs; Heart Rate; Hyperemia; Muscle Contraction; Stimulation, Chemical; Vasodilator Agents | 1972 |
Studies on the synthesis and release of adenosine triphosphate-8- 3 H in the isolated perfused cat adrenal gland.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adrenal Glands; Animals; Carbachol; Catecholamines; Cats; Chromaffin System; Chromatography, Ion Exchange; Chromatography, Thin Layer; Cytoplasmic Granules; Female; In Vitro Techniques; Male; Oxidative Phosphorylation; Perfusion; Tritium | 1972 |
Platelet aggregation inhibitors. I. Hydroxylamine: a potent inhibitor of platelet aggregation.
Topics: Adenosine; Adenosine Diphosphate; Animals; Blood Platelets; Collagen; Depression, Chemical; Hydroxylamines; In Vitro Techniques; Male; Purines; Rabbits; Stimulation, Chemical | 1972 |
Symposium on Myocardial Blood Flow in Man--Methods and Significance in Myocardial Disease: Pisa, Italy; June 10-12, 1971. Report of the session on acute hypoxia.
Topics: Acute Disease; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Blood Flow Velocity; Calcium; Cardiac Output; Coronary Circulation; Coronary Disease; Dogs; Glycolysis; Guinea Pigs; Heart; Humans; Hydrogen-Ion Concentration; Hypoxia; Lipid Metabolism; Mitochondria, Muscle; Myocardium; Oxygen Consumption; Propranolol; Rabbits | 1972 |
AMP inhibition of reactions of ADP with washed platelets from humans and rabbits.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Binding Sites; Blood Platelets; Carbon Dioxide; Carbon Isotopes; Glucose; Humans; In Vitro Techniques; Platelet Adhesiveness; Rabbits | 1972 |
Potentiating effect of adenosine on other inhibitors of platelet aggregation.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Blood Platelets; Dipyridamole; Humans; Platelet Adhesiveness; Prostaglandins; Pyridinium Compounds | 1972 |
Kinetic studies of adenosine kinase from Ehrlich ascites tumor cells.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Binding Sites; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Feedback; Kinetics; Mercaptopurine; Phosphotransferases; Protein Binding; Pyrimidines; Pyrroles; Ribonucleosides; Ribonucleotides; Structure-Activity Relationship | 1972 |
Adenine nucleotides and platelet function.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Biological Transport; Blood Platelets; Carbon Isotopes; Cell Membrane; Collagen; Energy Transfer; Ethanol; Hypoxanthines; Papaverine; Phosphorus Isotopes; Platelet Adhesiveness; Protein Binding; Thrombin | 1971 |
Ammonia forming mechanisms: deamination of 5'-adenylic acid (AMP) by some polychaete annelids.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aminohydrolases; Ammonia; Annelida; Carbon Isotopes; Chromatography, Paper; Deamination; Enzyme Activation; Hydrogen-Ion Concentration; Inosine Nucleotides; Osmolar Concentration; Time Factors | 1971 |
Aspects of nucleic acid metabolism during development of the brine shrimp Artemia salina.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Age Factors; Animals; Autoradiography; Centrifugation; Chromatography, Ion Exchange; Decapoda; DNA; Embryo, Nonmammalian; Guanine Nucleotides; Guanosine Triphosphate; Larva; Nucleotides; Phosphorus Isotopes; RNA; RNA, Ribosomal; RNA, Transfer; Spectrophotometry; Tritium | 1971 |
Excitation-contraction coupling in heart. 8. Influence of adenine nucleotides on calcium binding by subcellular fractions of rat heart.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Azides; Calcium; Hydrolysis; In Vitro Techniques; Inosine Nucleotides; Mitochondria; Myocardium; Oligomycins; Rats; Sarcoplasmic Reticulum | 1971 |
Involvement of platelets and microthrombi in experimental decompression sickness: similarities with disseminated intravascular coagulation.
Topics: Adenosine; Adenosine Diphosphate; Air; Animals; Blood Cell Count; Blood Platelets; Cerebral Cortex; Decompression Sickness; Disseminated Intravascular Coagulation; Erythrocyte Aggregation; Injections, Intra-Arterial; Injections, Intravenous; Lung; Male; Platelet Adhesiveness; Rabbits; Rats; Serotonin; Thrombosis | 1971 |
Comparison of the effects of drugs on the aggregation of hamster platelets in vivo and in vitro.
Topics: Adenosine; Adenosine Diphosphate; Animals; Aspirin; Blood Volume; Carbon Isotopes; Cheek; Cricetinae; Desipramine; Imipramine; In Vitro Techniques; Iontophoresis; Microcirculation; Platelet Adhesiveness; Sodium Salicylate; Tritium | 1971 |
Plasmodium berghei: in vitro incorporation of purine derivatives into nucleic acids.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Biological Transport, Active; Cell-Free System; DNA; Erythrocytes; Guanosine Triphosphate; Hydrogen-Ion Concentration; Models, Biological; Nucleic Acids; Nucleosides; Oxidative Phosphorylation; Plasmodium; Purines; Pyrimidines; RNA; Temperature; Tritium | 1971 |
Influence of adenosine and nagarse on palmitoly-CoA synthese in rat heart and liver mitochondria.
Topics: Acyltransferases; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Carbon Isotopes; Carnitine; Cattle; Coenzyme A; Endopeptidases; Kinetics; Ligases; Mitochondria, Liver; Mitochondria, Muscle; Myocardium; Nucleosides; Oxygen Consumption; Palmitic Acids; Rats; Temperature; Tritium | 1971 |
Control of adenylate kinase by prostaglandins E2 and E3.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Autoradiography; Blood Platelets; Brain; Carbon Isotopes; Carbon Radioisotopes; Chromatography, Thin Layer; Enzyme Activation; Humans; Hypoxanthines; In Vitro Techniques; Inosine; Kinetics; Models, Biological; Muscles; Phosphoric Monoester Hydrolases; Phosphotransferases; Plants; Prostaglandins; Protein Binding; Rats | 1971 |
[Relaxant effect of adenosine triphosphate and its related nucleotides on the guinea-pig taenia coli].
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Atropine; Colon; Depression, Chemical; Electric Stimulation; Guanine; Guanosine; Guinea Pigs; Imidazoles; In Vitro Techniques; Inosine; Muscle, Smooth; Nucleotides; Phenoxybenzamine; Phentolamine; Quinidine | 1971 |
Dissociation between platelet factor 3 availability and platelet aggregation.
Topics: Absorption; Adenosine; Adenosine Diphosphate; Aspirin; Blood Platelets; Collagen; Glycolysis; Humans; Indomethacin; Oxidative Phosphorylation; Platelet Adhesiveness; Purpura, Thrombocytopenic; Spectrum Analysis; Thromboplastin; Time Factors | 1971 |
Role of adenine nucleotides, adenosine, and inorganic phosphate in the regulation of skeletal muscle blood flow.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Anura; Dogs; Extracellular Space; Hindlimb; Muscle Contraction; Muscles; Oxygen Consumption; Phosphates; Rana pipiens; Regional Blood Flow; Vascular Resistance | 1971 |
Constitutional and acquired abnormalities of platelet aggregation.
Topics: Acid Phosphatase; Adenosine; Adenosine Diphosphate; Aminohydrolases; Anemia, Sideroblastic; Blood Platelet Disorders; Blood Platelets; Bolivia; Carbon Isotopes; Collagen; Environment; Epinephrine; Fibrinogen; Hemagglutination; Heparin Antagonists; Humans; Immune Sera; Megakaryocytes; Microscopy, Electron; Neuraminic Acids; Nucleotides; Peru; Platelet Adhesiveness; Purpura, Thrombocytopenic; Racial Groups; Thrombocytopenia; Uremia | 1970 |
[Synthesis of adenine nucleotides from exogenous adenosine in the perfused rat heart under normoxic conditions and after ischemia].
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Coronary Disease; Female; In Vitro Techniques; Kinetics; Myocardium; Perfusion; Rats; Rats, Inbred Strains | 1984 |
[ATP-activated ion conductance in the somatic membrane of the neurons of mammalian sensory ganglia].
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cations, Monovalent; Cats; Cell Membrane Permeability; Ganglia; Ion Channels; Membrane Potentials; Neurons, Afferent; Rats; Receptors, Cell Surface; Receptors, Purinergic | 1984 |
Effects of adenosine, adenosine triphosphate and structural analogues on glucagon secretion from the perfused pancreas of rat in vitro.
Topics: 2-Chloroadenosine; 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Glucagon; In Vitro Techniques; Male; Nucleotidases; Pancreas; Rats; Theophylline | 1984 |
Inhibition of ADP-induced responses in human platelets by agents elevating the cyclic AMP level: comparison of aggregation and shape change.
Topics: Adenosine; Adenosine Diphosphate; Alprostadil; Blood Platelets; Cyclic AMP; Humans; In Vitro Techniques; Platelet Aggregation; Platelet Membrane Glycoproteins; Prostaglandins E; Receptors, Cell Surface | 1984 |
Adenosine receptors mediating cyclic AMP production in the rat hippocampus.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adrenergic Agonists; Animals; Cyclic AMP; Guanosine Monophosphate; Hippocampus; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic | 1982 |
Direct evidence against a role of ATP as the nonadrenergic, noncholinergic inhibitory neurotransmitter in guinea pig tenia coli.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Atropine; Colon; Electric Stimulation; Guanethidine; Guinea Pigs; Histamine; Muscle Relaxation; Neurotransmitter Agents | 1982 |
Purine metabolism of erythrocytes in myotonic dystrophy.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Erythrocytes; Humans; Muscular Dystrophies; Purines | 1980 |
Biochemical approaches to enhancement of antitumor drug selectivity: selective protection of cells from 6-thioguanine and 6-mercaptopurine by adenosine.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cell Count; Cell Line; Drug Interactions; Drug Resistance; Liver Neoplasms, Experimental; Mercaptopurine; Phosphoribosyl Pyrophosphate; Rats; Thioguanine; Uridine Diphosphate; Uridine Triphosphate | 1980 |
[Effect of various precursors on the synthesis of adenine and uracil nucleotides in the rat heart (author's transl)].
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Female; Isoproterenol; Myocardium; Phosphocreatine; Phosphoribosyl Pyrophosphate; Rats; Ribose; Uracil Nucleotides; Uridine; Uridine Triphosphate | 1980 |
Mechanism of action of ATP on intestinal epithelial cells. Cyclic AMP-mediated stimulation of active ion transport.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Alprostadil; Animals; Biological Transport, Active; Cyclic AMP; Guanylyl Imidodiphosphate; Guinea Pigs; Intestine, Small; Kinetics; Male; Prostaglandins E; Vasoactive Intestinal Peptide | 1982 |
Inhibition of fast axonal transport by erythro-9-[3-(2-hydroxynonyl)]adenine.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Axonal Transport; Cycloleucine; Deoxyadenosines; Rana esculenta; Rana temporaria; Sciatic Nerve; Thionucleosides | 1984 |
Temperature-sensitive mutant rho-115 rho-RNA binary complexes, and stabilization by substrates and analogues.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Mutation; Poly C; Rho Factor; RNA, Messenger; Temperature; Transcription Factors | 1982 |
Rat heart mitochondria release adenosine.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Biological Transport; In Vitro Techniques; Mitochondria, Heart; Mitochondrial ADP, ATP Translocases; Oxygen Consumption; Rats | 1983 |
Adenine nucleotide degradation by the obligate intracellular bacterium Rickettsia typhi.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Adenylate Kinase; ATP Synthetase Complexes; Biological Transport, Active; Multienzyme Complexes; Phosphotransferases; Rickettsia typhi | 1980 |
AMP metabolism in the marine bacterium Beneckea natriegens.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenylate Kinase; Inosine; Nucleotidases; Vibrio; Vibrionaceae | 1980 |
Effects of adenosine analogs and adenine nucleotides on adenosine 5'-diphosphate-induced rat platelet aggregation.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Humans; In Vitro Techniques; Kinetics; Papaverine; Phosphoric Diester Hydrolases; Platelet Aggregation; Rats | 1980 |
Adenosine receptor activation by adenine nucleotides requires conversion of the nucleotides to adenosine.
Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Cyclic AMP; Humans; In Vitro Techniques; Kinetics; Nucleotidases; Receptors, Cell Surface; Receptors, Purinergic; Theophylline; Time Factors | 1980 |
Identification of two distinct adenosine diphosphate receptors in human platelets.
Topics: Adenosine; Adenosine Diphosphate; Blood Platelets; Chymotrypsin; Cyclic AMP; Fibrinogen; Humans; In Vitro Techniques; Platelet Aggregation; Receptors, Cell Surface; Receptors, Purinergic; Thionucleotides | 1980 |
Affinity labeling of a human platelet membrane protein with 5'-p-fluorosulfonylbenzoyl adenosine. Concomitant inhibition of ADP-induced platelet aggregation and fibrinogen receptor exposure.
Topics: Adenosine; Adenosine Diphosphate; Affinity Labels; Blood Platelets; Fibrinogen; Humans; Kinetics; Membrane Proteins; Platelet Aggregation; Platelet Membrane Glycoproteins; Protein Binding; Receptors, Cell Surface | 1981 |
Role of membrane-bound 5'-nucleotidase in nucleotide uptake by the moderate halophile Vibrio costicola.
Topics: 5'-Nucleotidase; Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Biological Transport, Active; Cell Membrane; Kinetics; Magnesium; Nucleotidases; Vibrio | 1982 |
Demonstration of a putative adenosine receptor in rabbit aorta.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Aorta, Thoracic; Dipyridamole; Kinetics; Microsomes; Muscle Relaxation; Muscle, Smooth, Vascular; Rabbits; Receptors, Cell Surface; Receptors, Purinergic; Subcellular Fractions; Thioinosine | 1982 |
Adenosine receptor-mediated accumulation of adenosine 3',5'-monophosphate in guinea pig thyroid tissue.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cyclic AMP; Female; Guinea Pigs; Male; Receptors, Cell Surface; Receptors, Purinergic; Thyroid Gland; Time Factors | 1982 |
Adenosine-induced slow ionic currents in the Xenopus oocyte.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Chlorides; Female; Ion Channels; Membrane Potentials; Oocytes; Ovum; Potassium; Theophylline; Xenopus laevis | 1982 |
The anatomical distribution of ADPase activity in the rabbit aorta.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Aorta, Abdominal; Aorta, Thoracic; Apyrase; Inosine; Male; Phosphoric Monoester Hydrolases; Rabbits | 1982 |
A new method that investigates superoxide versus respiration in vitro using bioluminescence and Sepharose-bound adenosine derivatives.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Luminescent Measurements; Magnetic Resonance Spectroscopy; Methods; Mitochondria, Liver; Oxygen; Oxygen Consumption; Ozone; Rats; Sepharose; Superoxides | 1982 |
Evidence on the existence of a purine ligand induced conformational change in the active site of bovine pancreatic ribonuclease A studied by proton nuclear magnetic resonance spectroscopy.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Binding Sites; Endoribonucleases; Guanosine; Guanosine Monophosphate; Magnetic Resonance Spectroscopy; Protein Conformation; Purine Nucleosides; Ribonuclease, Pancreatic; Structure-Activity Relationship | 1982 |
Platelet aggregation and exposure of fibrinogen receptors by prostaglandin endoperoxide analogues.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Dose-Response Relationship, Drug; Fibrinogen; Iodine Radioisotopes; Platelet Aggregation; Platelet Membrane Glycoproteins; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandins H; Receptors, Cell Surface | 1983 |
Role of purines in acetylcholine-induced coronary vasodilation.
Topics: Acetylcholine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Coronary Vessels; Cyclic AMP; Cyclic GMP; Guinea Pigs; Heart; In Vitro Techniques; Receptors, Muscarinic; Vasodilation | 1982 |
Biological activities and spectroscopic properties of chromophoric and fluorescent analogs of adenine nucleoside and nucleotides, 2',3'-O-(2,4,6-trinitrocyclohexadienylidene) adenosine derivatives.
Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenylate Kinase; Alkaline Phosphatase; Animals; Cattle; Cerebral Cortex; Escherichia coli; Fluorescent Dyes; Intestinal Mucosa; Muscles; Rabbits; Sodium-Potassium-Exchanging ATPase; Structure-Activity Relationship; Swine | 1982 |
Kinetic studies of adenosine kinase from L1210 cells: a model enzyme with a two-site ping-pong mechanism.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Kinase; Adenosine Monophosphate; Adenosine Triphosphate; Animals; In Vitro Techniques; Kinetics; Leukemia L1210; Magnesium; Mice; Models, Chemical; Phosphorylation; Phosphotransferases | 1983 |
Adenosine- and ADP-phosphorylating capacity of herpes simplex virus-induced thymidine kinase enzyme complex.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Kinase; Adenosine Monophosphate; Chromatography, Affinity; Phosphorylation; Simplexvirus; Substrate Specificity; Thymidine; Thymidine Kinase | 1983 |
Effect of adenine nucleotides and gamma radiation on the transport of TEMPOL across the erythrocyte membrane.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Biological Transport; Cattle; Cobalt Radioisotopes; Cyclic AMP; Cyclic N-Oxides; Erythrocyte Membrane; Gamma Rays; Spin Labels | 1983 |
Rabbit muscle phosphofructokinase. 1. Activation by affinity labeling approximately two adenosine cyclic 3',5'-monophosphate binding sites per tetramer.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Affinity Labels; Animals; Binding Sites; Cyclic AMP; Enzyme Activation; Muscles; Phosphofructokinase-1; Rabbits | 1983 |
A cytoplasmic requirement of red cells for invasion by malarial parasites.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cyclic AMP; Cytoplasm; Erythrocyte Membrane; Erythrocytes; Fetal Blood; Hematocrit; Humans; In Vitro Techniques; Malaria; Plasmodium falciparum; Vanadates; Vanadium | 1983 |
Adenine nucleotide levels and adenosine metabolism in cultured calvarial bone.
Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Bone and Bones; Cells, Cultured; Deoxyadenosines; Dinoprostone; Hypoxanthine; Hypoxanthines; Inosine; Inosine Monophosphate; Mice; Parathyroid Hormone; Prostaglandins E; Uric Acid | 1984 |
Evidence for distinct catabolic pathways of adenine ribonucleotides and deoxyribonucleotides in human T lymphoblastoid cells.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Cell Line; Coformycin; Deoxyadenine Nucleotides; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Inosine; Kinetics; Pentostatin; Structure-Activity Relationship; T-Lymphocytes | 1984 |
Platelet serotonin uptake during myocardial ischemia.
Topics: Adenosine; Adenosine Diphosphate; Animals; Blood Platelets; Cats; Coronary Disease; Epoprostenol; Female; Ligation; Male; Platelet Aggregation; Platelet Count; Serotonin | 1983 |
Physiological concentrations of ADP stimulate the release of prostacyclin from bovine aortic endothelial cells.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Aorta; Cattle; Cells, Cultured; Endothelium; Epoprostenol | 1984 |
Luminescence studies on the conformational behavior of horse-liver alcohol dehydrogenase.
Topics: Adenosine; Adenosine Diphosphate; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Animals; Energy Transfer; Ethanol; Horses; Liver; Luminescent Measurements; Mathematics; NAD; Protein Conformation; Tryptophan | 1984 |
Kinetic studies of the reaction mechanism of rat liver phosphoglycerate kinase in the direction of ADP utilization.
Topics: 2,3-Diphosphoglycerate; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Diphosphoglyceric Acids; Kinetics; Liver; Magnesium; Phosphoglycerate Kinase; Rats | 1983 |
Resonance energy transfer between the adenosine 5'-diphosphate site of glutamate dehydrogenase and a guanosine 5'-triphosphate site containing a tyrosine labeled with 5'-[p-(fluorosulfonyl)benzoyl]-1,N6-ethenoadenosine.
Topics: Adenosine; Adenosine Diphosphate; Affinity Labels; Animals; Cattle; Energy Transfer; Glutamate Dehydrogenase; Guanosine Triphosphate; Kinetics; Liver; Lysine; Tyrosine | 1983 |
[Acceleration of the synthesis of cardiac adenine nucleotides from adenosine as affected by propranolol].
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Chromatography, High Pressure Liquid; Coronary Disease; Female; Heart; In Vitro Techniques; Male; Myocardium; Oxygen Consumption; Phosphorylation; Propranolol; Rats; Rats, Inbred Strains | 1984 |
Compartmentalized ATP pools produced from adenosine are nuclear pools.
Topics: Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Cell Compartmentation; Cell Line; Cell Nucleus; Cell Transformation, Neoplastic; Chick Embryo; Chlorocebus aethiops; Fibroblasts; Interphase; Mice | 1980 |
Distance relationships between the catalytic site labeled with 4-(iodoacetamido)salicylic acid and regulatory sites of glutamate dehydrogenase.
Topics: Adenosine; Adenosine Diphosphate; Allosteric Site; Amino Acids; Animals; Binding Sites; Cattle; Energy Transfer; Enzyme Activation; Fluorescent Dyes; Glutamate Dehydrogenase; Guanosine Triphosphate; Iodoacetamide; Kinetics; Liver; Salicylates; Spectrometry, Fluorescence | 1984 |
[Effect of papaverine on the absorption and metabolism of 14C- adenosine and 14C-adenine in thymocytes].
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenylate Kinase; Animals; Carbon Radioisotopes; Extracellular Space; Hypoxanthine; Hypoxanthines; Inosine; Papaverine; Rats; Rats, Inbred Strains; Thymus Gland | 1984 |
Release of adenosine, inosine and hypoxanthine from rabbit non-myelinated nerve fibres at rest and during activity.
Topics: Action Potentials; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antimetabolites; Cyanides; Deoxyglucose; Glucose; Hydrolysis; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Nerve Fibers; Rabbits | 1984 |
Rapid analysis of adenosine, AMP, ADP, and ATP by anion-exchange column chromatography.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Chromatography, Ion Exchange; Erythrocytes; Humans | 1984 |
Energy levels at systole vs. diastole in normal hamster hearts vs. myopathic hamster hearts.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cricetinae; Energy Metabolism; Heart Failure; Lactates; Lactic Acid; Mesocricetus; Myocardial Contraction; Myocardium; Oxygen Consumption; Phosphates; Phosphocreatine; Systole | 1983 |
Inhibition of human natural killer cell reactivity by exogenous adenosine 5'-triphosphate.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Binding Sites; Cytotoxicity, Immunologic; Humans; Immunosuppressive Agents; Killer Cells, Natural; Mice; Rats | 1984 |
Adenosine as a mediator of postcontraction hyperemia in dog gracilis muscle.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Animals; Dipyridamole; Dogs; Electric Conductivity; Female; Male; Muscle Contraction; Muscles; Oxygen Consumption; Perfusion | 1984 |
Antagonism of tetrodotoxin- and procaine-induced axonal blockade by adenine nucleotides in the frog sciatic nerve.
Topics: Action Potentials; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Axons; In Vitro Techniques; Neural Conduction; Pentobarbital; Procaine; Rana ridibunda; Sciatic Nerve; Sodium Chloride; Tetrodotoxin | 1984 |
Deaza analogues of adenosine as inhibitors of blood platelet aggregation.
Topics: Adenosine; Adenosine Diphosphate; Collagen; Humans; In Vitro Techniques; Kinetics; Platelet Aggregation; Structure-Activity Relationship | 1984 |
Mitochondrial oxidative phosphorylation: tissue oxygen sensor for regulation of coronary flow.
Topics: 2,4-Dinitrophenol; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Amobarbital; Animals; Coronary Circulation; Creatine; Dinitrophenols; Energy Metabolism; In Vitro Techniques; Male; Mitochondria, Heart; Oxidative Phosphorylation; Oxygen Consumption; Rats; Rats, Inbred Strains; Theophylline | 1984 |
High-pressure liquid chromatographic-fluorometric detection of adenosine and adenine nucleotides: application to endogenous content and electrically induced release of adenyl purines in guinea pig vas deferens.
Topics: Acetaldehyde; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adrenergic Fibers; Animals; Chromatography, High Pressure Liquid; Electric Stimulation; Electrophysiology; Fluorometry; Guinea Pigs; In Vitro Techniques; Male; Vas Deferens | 1984 |
Efflux of radioactive nucleotides from mouse pancreatic islets prelabelled with 2-3H-adenosine.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antimycin A; Cells, Cultured; Glipizide; Glucose; Inosine; Insulin; Islets of Langerhans; Keto Acids; Male; Mice; Nucleotides; Pyruvates | 1982 |
Stored human platelets retain full aggregation potential in response to pairs of aggregating agents.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Arachidonic Acid; Arachidonic Acids; Blood Preservation; Citrates; Collagen; Drug Synergism; Epinephrine; Glucose; Humans; Platelet Aggregation; Thromboxane B2; Time Factors | 1982 |
Adenosine diphosphate-degrading activity in placenta.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Female; Humans; Placenta; Pregnancy; Umbilical Arteries | 1983 |
Growth inhibition of human tumor cells in soft-agar cultures by treatment with low levels of adenosine 5'-triphosphate.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Agar; Cell Division; Cell Line; Cell Survival; Culture Media; DNA Replication; Humans; Neoplasms | 1983 |
Effect of streptozotocin-induced diabetes on the metabolism of ADP, AMP and adenosine in the pulmonary circulation of rat isolated lung.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Diabetes Mellitus, Experimental; Lung; Male; Pulmonary Circulation; Rats; Rats, Inbred Strains | 1983 |
Can ATP stimulate P1-receptors in guinea-pig atrium without conversion to adenosine?
Topics: Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Biotransformation; Dipyridamole; Female; Guinea Pigs; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Receptors, Drug; Receptors, Purinergic; Theophylline | 1982 |
Dual action of high energy adenine nucleotides in comparison with responses evoked by other adenine derivatives and intramural nerve stimulation on smooth muscle.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Organophosphonates; Organophosphorus Compounds; Prostaglandins; Stomach | 1981 |
Noninvasive 31P NMR probes of free Mg2+, MgATP, and MgADP in intact Ehrlich ascites tumor cells.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Carcinoma, Ehrlich Tumor; Cell Compartmentation; Cells, Cultured; Cytosol; Female; Glucose; Magnesium; Magnetic Resonance Spectroscopy; Mice; Phosphates | 1980 |
Active-site-dependent, thrombin-induced release of adenine nucleotides from cultured human endothelial cells.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Arachidonic Acids; Binding Sites; Cells, Cultured; Chromatography, Thin Layer; Endothelium; Humans; Thrombin; Tritium | 1981 |
5'-Methylthioadenosine and 2',5'-dideoxyadenosine blockade of the inhibitory effects of adenosine on ADP-induced platelet aggregation by different mechanisms.
Topics: Adenosine; Adenosine Diphosphate; Adenylyl Cyclases; Blood Platelets; Deoxyadenosines; Dideoxyadenosine; Humans; In Vitro Techniques; Platelet Aggregation; Prostaglandins E; Thionucleosides | 1980 |
Distribution of P1- and P2-purinoceptors in the guinea-pig and frog heart.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Dipyridamole; Female; Guinea Pigs; Heart; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Rana pipiens; Receptors, Drug; Receptors, Purinergic; Theophylline | 1981 |
Inhibition of human and rat platelet aggregation by extracts of Mo-er (Auricularia auricula).
Topics: Adenosine; Adenosine Diphosphate; Animals; Deoxyadenosines; Depression, Chemical; Dideoxyadenosine; Fungi; Humans; Plant Extracts; Platelet Aggregation; Rats; Rats, Inbred Strains; Thionucleosides | 1982 |
Affinity labeling of rabbit skeletal muscle phosphorylase kinase by 5'-(p-fluorosulfonylbenzoyl) adenosine.
Topics: Adenosine; Adenosine Diphosphate; Affinity Labels; Animals; Binding Sites; Macromolecular Substances; Magnesium; Muscles; Phosphorylase Kinase; Rabbits; Time Factors | 1982 |
Improved functional recovery of ischemic myocardium by suppression of adenosine catabolism.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Heart Arrest, Induced; In Vitro Techniques; Male; Myocardium; Perfusion; Rats; Rats, Inbred Strains | 1982 |
Affinity labeling of a guanosine 5'-triphosphate site of glutamate dehydrogenase by a fluorescent nucleotide analogue, 5'-[p-(fluorosulfonyl)benzoyl]-1,N6-ethenoadenosine.
Topics: Adenosine; Adenosine Diphosphate; Affinity Labels; Animals; Binding Sites; Cattle; Ethenoadenosine Triphosphate; Glutamate Dehydrogenase; Guanosine Triphosphate; In Vitro Techniques; Kinetics; Liver | 1982 |
Uptake of adenosine and release of adenine derivatives in mammalian non-myelinated nerve fibres at rest and during activity.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Electric Stimulation; In Vitro Techniques; Nerve Fibers; Rabbits; Vagus Nerve | 1982 |
Synergistic responses and receptor occupancy in rabbit blood platelets.
Topics: Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Animals; Apyrase; Blood Platelets; Clomipramine; Drug Synergism; Epinephrine; Platelet Aggregation; Rabbits; Receptors, Adrenergic; Receptors, Serotonin; Serotonin; Yohimbine | 1982 |
The thermodynamics of a negatively interacting allosteric effector system. The glutamate dehydrogenase . NADPH . ADP complexes.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Allosteric Regulation; Allosteric Site; Animals; Cattle; Glutamate Dehydrogenase; Liver; NADP; Protein Binding; Thermodynamics | 1980 |
Adenine nucleotides as tools in platelet studies.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Blood Platelets; Humans; In Vitro Techniques; Platelet Aggregation; Sheep | 1981 |
Hydrolysis of ATP in chemical models.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Cetrimonium; Cetrimonium Compounds; Chemical Phenomena; Chemistry; Hydrogen-Ion Concentration; Quaternary Ammonium Compounds | 1981 |
Specificity and mechanism of nucleotide uptake by adrenal chromaffin granules.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adrenal Medulla; Animals; Cattle; Chromaffin Granules; Chromaffin System; Guanosine Triphosphate; Kinetics; Membrane Potentials; Norepinephrine; Nucleotides; Uridine Triphosphate | 1981 |
Release of [14C]adenosine derivatives from superfused synaptosome preparations. Effects of depolarizing agents and metabolic inhibitors.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cerebral Cortex; Guinea Pigs; Iodoacetates; Lactates; Oligomycins; Ouabain; Potassium; Sodium Cyanide; Synaptosomes; Tetrodotoxin; Veratridine | 1980 |
Interaction of adenosine and adenylnucleotides with the human platelet membrane. Further characterization of the ADP binding sites.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Binding Sites; Binding, Competitive; Blood Platelets; Carbon Radioisotopes; Cell Membrane; Humans; Kinetics | 1980 |
ATP- and ADP-induced rat platelet aggregation: significance of plasma in ATP-induced aggregation.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Creatine; Creatine Kinase; Female; Humans; Male; Phosphocreatine; Plasma; Platelet Aggregation; Rats | 1980 |
Action of coenzyme A on adenine derivative receptors in isolated tissues.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Coenzyme A; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; In Vitro Techniques; Muscle Contraction; Rabbits; Rats; Receptors, Drug; Theophylline | 1980 |
Evidence against purinergic inhibitory nerves in the vagal pathway to the opossum lower esophageal sphincter.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Electric Stimulation; Electrophysiology; Esophagogastric Junction; Female; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Neural Inhibition; Opossums; Rest; Tetrodotoxin; Vagus Nerve | 1980 |
Effect of varying pH [H+] on the metabolism of adenosine in isolated heart cells.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Biological Transport; Cells, Cultured; Chick Embryo; Hydrogen-Ion Concentration; Hypoxanthines; Inosine; Myocardium; Theophylline | 1980 |
The metabolism of purine and pyrimidine nucleotides in rat cortex during insulin-induced hypoglycemia and recovery.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cerebral Cortex; Chromatography, High Pressure Liquid; Hypoglycemia; Insulin Coma; Male; Purine Nucleosides; Purine Nucleotides; Pyrimidine Nucleosides; Pyrimidine Nucleotides; Rats | 1981 |
The dephosphorylation of AMP and IMP by a soluble low Km 5'nucleotidase from human seminal plasma: some regulatory aspects.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Humans; Hypoxanthine; Hypoxanthines; Inosine; Inosine Monophosphate; Male; Phosphates; Semen; Solubility | 1995 |
Production of adenosine and nucleoside analogs by the exchange reaction catalyzed by rat liver adenosine kinase.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Kinase; Adenosine Monophosphate; Animals; Carbon Radioisotopes; Kinetics; Liver; Male; Nucleosides; Nucleotides; Rats; Rats, Wistar | 1995 |
Enhancement of differentiation induction of mouse myelomonocytic leukemic cells by extracellular ATP.
Topics: 1-Methyl-3-isobutylxanthine; Actins; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Cell Differentiation; Cytosol; Dose-Response Relationship, Drug; Interleukin-6; Kinetics; Leukemia, Experimental; Leukemia, Myeloid; Mice; Phagocytosis; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-jun; Proto-Oncogene Proteins c-myc; Receptors, Fc; Recombinant Proteins; Triazines; Tumor Cells, Cultured | 1994 |
Synergistic activation of DNA synthesis in astrocytes by fibroblast growth factors and extracellular ATP.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Cerebral Cortex; DNA; Dose-Response Relationship, Drug; Drug Synergism; Fibroblast Growth Factor 1; Fibroblast Growth Factor 2; Humans; Kinetics; Rats; Recombinant Proteins; Thionucleotides | 1994 |
Inhibition of HGF/SF-induced membrane ruffling and cell motility by transient elevation of cytosolic free Ca2+.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Calcium; Cell Line; Cell Membrane; Cell Movement; Chelating Agents; Colonic Neoplasms; Cytosol; Egtazic Acid; Hepatocyte Growth Factor; Humans; Ionomycin; Kinetics; Microscopy, Electron, Scanning; Time Factors; Tumor Cells, Cultured; Video Recording | 1995 |
Protection against injury during ischemia and reperfusion by acadesine derivatives GP-1-468 and GP-1-668. Studies in the transplanted rat heart.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aminoimidazole Carboxamide; Animals; Coronary Circulation; Heart Transplantation; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Rats; Rats, Inbred Lew; Ribonucleosides; Ribonucleotides; Ventricular Pressure | 1995 |
The ATP/ADP binding domains of actin are conserved in nucleosome complexed with histone H1 and high mobility group-17 protein.
Topics: Actins; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Sequence; Binding Sites; Calcium; High Mobility Group Proteins; Histones; Molecular Sequence Data; Nucleosomes; Phosphates; Protein Structure, Secondary; Sequence Homology | 1995 |
Does interstitial adenosine mediate acute hibernation of guinea pig myocardium?
Topics: 5'-Nucleotidase; Acute Disease; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cytosol; Guinea Pigs; Heart; Inosine; Lactates; Lactic Acid; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Stunning; Myocardium; Phosphorylation; Theophylline | 1995 |
Myogenic and agonist induced responses of coronary venules after cold hyperkalaemic cardioplegia.
Topics: Adenosine; Adenosine Diphosphate; Adrenergic beta-Agonists; Animals; Cardiopulmonary Bypass; Coronary Vessels; Endothelium, Vascular; Female; Guanidines; Heart Arrest, Induced; Isoproterenol; Male; Muscle, Smooth, Vascular; Nitroprusside; Pinacidil; Serotonin; Swine; Vasodilator Agents | 1995 |
The AMP-adenosine cycle is active during normoxia and impaired in ATP depletion in isolated rabbit cardiomyocytes.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cell Hypoxia; Cells, Cultured; Glycolysis; Iodoacetates; Iodoacetic Acid; Kinetics; Myocardium; Rabbits | 1994 |
[Effect of tissue damage mediators on the expression of surface antigens by human lymphocytes in vitro].
Topics: Adenosine; Adenosine Diphosphate; Amino Acid Sequence; Antigens, CD; Antigens, Surface; Female; Humans; Lymphocytes; Male; Molecular Sequence Data; Neuropeptides; Pyrrolidonecarboxylic Acid; Wounds and Injuries | 1995 |
P2-purinoceptor-mediated inhibition of noradrenaline release in rat atria.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antihypertensive Agents; Atropine; Desipramine; Dose-Response Relationship, Drug; Electric Stimulation; Heart Atria; Indomethacin; Male; Norepinephrine; Phenethylamines; Protein Synthesis Inhibitors; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Suramin; Triazines; Xanthines; Yohimbine | 1995 |
Activation by ATP of a P2U 'nucleotide' receptor in an exocrine cell.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Chlorides; Ducks; Exocrine Glands; Nasal Cavity; Patch-Clamp Techniques; Potassium; Receptors, Purinergic P2; Uridine Triphosphate | 1995 |
Existence of rolipram-sensitive phosphodiesterase in rat megakaryocyte.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Diphosphate; Adenylyl Cyclases; Animals; Bone Marrow Cells; Calcimycin; Calcium Channels; Colforsin; Cyclic AMP; Electrophysiology; Female; In Vitro Techniques; Inosine Triphosphate; Isoquinolines; Male; Megakaryocytes; Nystatin; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Protein Kinase C; Pyrrolidinones; Rats; Rats, Wistar; Rolipram | 1993 |
Extracellular ATP activates a cation conductance and a K+ conductance in cultured microglial cells from mouse brain.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Animals, Newborn; Brain; Calcium; Cells, Cultured; Embryo, Mammalian; Fura-2; Ion Channels; Membrane Potentials; Mice; Microglia; Potassium Channels; Rats; Receptors, Purinergic P2 | 1993 |
Alpha 1-adrenoceptor activation increases ecto-5'-nucleotidase activity and adenosine release in rat cardiomyocytes by activating protein kinase C.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; In Vitro Techniques; Indoles; Male; Maleimides; Methoxamine; Myocardium; Norepinephrine; Protein Kinase C; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Tetradecanoylphorbol Acetate | 1995 |
Irreversible inhibition of human natural killer cell natural cytotoxicity by modification of the extracellular membrane by the adenine nucleotide analog 5'-p-(fluorosulfonyl)benzoyl adenosine.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Benzoates; Burkitt Lymphoma; Cell Line; Cell Membrane; Cytoplasmic Granules; Cytotoxicity, Immunologic; Extracellular Space; Granzymes; Humans; Immunosuppressive Agents; Killer Cells, Natural; Leukemia, Erythroblastic, Acute; Phenylmethylsulfonyl Fluoride; Serine Endopeptidases; Tumor Cells, Cultured | 1995 |
Oxypurinol-enhanced postischemic recovery of the rat brain involves preservation of adenine nucleotides.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Blood Pressure; Electrochemistry; Hydrogen-Ion Concentration; Ischemic Attack, Transient; Kinetics; Male; Oxypurinol; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Respiration; Xanthine Oxidase | 1995 |
Interactions of nucleotides with fully unadenylylated glutamine synthetase from Salmonella typhimurium.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenylyl Imidodiphosphate; Amino Acid Sequence; Binding, Competitive; Crystallography, X-Ray; Fourier Analysis; Glutamate-Ammonia Ligase; Guanosine Diphosphate; Kinetics; Models, Molecular; Salmonella typhimurium | 1994 |
Intermittent v continuous ischemia decelerates adenylate breakdown and prevents norepinephrine release in reperfused rabbit heart.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Analysis of Variance; Animals; Heart; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Kinetics; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Norepinephrine; Purines; Rabbits; Time Factors; Ventricular Function, Left | 1995 |
Effects of preservation solutions on cortical and medullary mitochondria of rat kidney.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Allopurinol; Animals; Glucose; Glutathione; Hypertonic Solutions; Insulin; Kidney; Kidney Cortex; Kidney Medulla; Male; Mannitol; Mitochondria; Organ Preservation; Organ Preservation Solutions; Oxygen Consumption; Potassium Chloride; Procaine; Raffinose; Rats; Rats, Wistar; Time Factors | 1995 |
Contribution of endothelium and cardiomyocytes to hypoxia-induced adenosine release.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Cell Hypoxia; Coronary Circulation; Coronary Vessels; Endothelium, Vascular; Energy Metabolism; Heart; Male; Muscle Proteins; Myocardium; Perfusion; Rats; Rats, Sprague-Dawley; Uric Acid; Vasodilation | 1994 |
Endothelium-dependent contraction of canine coronary artery is enhanced after 24 hours of preservation with University of Wisconsin solution.
Topics: Acetylcholine; Adenosine; Adenosine Diphosphate; Allopurinol; Animals; Coronary Vessels; Dinoprost; Dogs; Endothelium, Vascular; Glutathione; Hypoxia; In Vitro Techniques; Insulin; Isoproterenol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Organ Preservation; Organ Preservation Solutions; Potassium; Raffinose | 1995 |
In vivo correlation between liver and blood energy status as evidenced by chronic treatment of carbon tetrachloride and adenosine to rats.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Blood; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Liver; Liver Diseases; Nucleotides; Phosphates; Rats; Rats, Wistar | 1994 |
Responses of porcine epicardial venules to neurohumoral substances.
Topics: Acetylcholine; Adenosine; Adenosine Diphosphate; Animals; Arterioles; Female; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Neurotransmitter Agents; Nitroprusside; Norepinephrine; Pericardium; Serotonin; Swine; Venules | 1993 |
ATP- and UTP-induced currents in macrophages and macrophage polykaryons.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Cell Membrane; Cells, Cultured; Cytosol; Egtazic Acid; Electric Stimulation; Glutamates; Glutamic Acid; Macrophages, Peritoneal; Magnesium; Meglumine; Membrane Potentials; Mice; Models, Biological; Potassium Channels; Quinine; Uridine Triphosphate | 1993 |
Stimulation of reactive astrogliosis in vivo by extracellular adenosine diphosphate or an adenosine A2 receptor agonist.
Topics: Adenosine; Adenosine Diphosphate; Animals; Astrocytes; Fluorescent Antibody Technique; Glial Fibrillary Acidic Protein; Immunohistochemistry; Male; Microinjections; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Xanthines | 1994 |
Two-dimensional transferred nuclear Overhauser effect spectroscopy (TRNOESY) studies of nucleotide conformations in arginine kinase complexes.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arginine Kinase; Binding Sites; Magnetic Resonance Spectroscopy; Molecular Structure; Muscles; Nephropidae; Nucleic Acid Conformation; Protons; Thermodynamics | 1994 |
In vivo and ex vivo effects of adenosine A1 and A2 receptor agonists on platelet aggregation in the rabbit.
Topics: Adenosine; Adenosine Diphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P1 Receptor Agonists; Rabbits | 1994 |
ATP-stimulated electrolyte and mucin secretion in the human intestinal goblet cell line HT29-Cl.16E.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Barium; Cell Line; Chloride Channels; Chlorides; Humans; Intestinal Mucosa; Mucins; Potassium Channels; Quinidine; Quinine | 1994 |
Activation of specific ATP receptors induces a rapid increase in intracellular calcium ions in rat hypothalamic neurons.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Cytosol; Fetus; Guanosine Triphosphate; Hypothalamus; Kinetics; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Neurotransmitter; Receptors, Purinergic P2; Structure-Activity Relationship; Suramin | 1994 |
Mobilization of Ca2+ influx, but not of stored Ca2+, by extracellular ATP in rat submandibular gland acini.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Carbachol; Dose-Response Relationship, Drug; Epinephrine; Guanosine Triphosphate; Hexokinase; Magnesium; Male; Nifedipine; Pancreas; Rats; Rats, Sprague-Dawley; Submandibular Gland; Uridine Triphosphate; Verapamil | 1994 |
Prevention of mucosal reperfusion damage after orthotopic small bowel autotransplantation in cats.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Allopurinol; Animals; Biomarkers; Cats; Cold Temperature; Energy Metabolism; Enzymes; Female; Glutathione; Insulin; Intestinal Mucosa; Intestine, Small; Male; Organ Preservation Solutions; Raffinose; Reperfusion Injury; Tissue Preservation; Transplantation, Autologous | 1994 |
Subtypes of purinoceptors in rat and dog urinary bladder smooth muscles.
Topics: Acetylcholine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Dogs; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Theophylline; Thionucleotides; Triazines; Urinary Bladder | 1994 |
Extracellular ATP promotes cellular growth of glomerular mesangial cells mediated via phospholipase C.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cells, Cultured; DNA; Enzyme Activation; Glomerular Mesangium; Inositol 1,4,5-Trisphosphate; Kinetics; Male; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Thymidine; Type C Phospholipases | 1994 |
Purine- and nucleotide-mediated relaxation of rabbit thoracic aorta: common and different sites of action.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; In Vitro Techniques; Inosine; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nucleotides; Purines; Rabbits; Suramin; Uridine Triphosphate; Vasodilator Agents | 1994 |
Endothelial nucleotide catabolism and adenosine production.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Cells, Cultured; Endothelium, Vascular; Humans; L-Lactate Dehydrogenase; Nucleotides; Umbilical Cord | 1994 |
Adenosine induces contractions in suncus ileum.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Atropine; Dose-Response Relationship, Drug; Electric Stimulation; Ileum; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Primates; Receptors, Purinergic; Theophylline | 1993 |
Metabolic, ionic, and secretory response to D-glucose in islets from rats with acquired or inherited non-insulin-dependent diabetes.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Diabetes Mellitus, Type 2; Glucose; Islets of Langerhans; Phosphates; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar; Rubidium Radioisotopes; Streptozocin | 1993 |
Infarct size-limiting effect of ischemic preconditioning is blunted by inhibition of 5'-nucleotidase activity and attenuation of adenosine release.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Dogs; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Time Factors | 1994 |
Inhibition of cancer growth and selective glutathione depletion in Ehrlich tumour cells in vivo by extracellular ATP.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cell Division; Erythrocytes; Glutathione; Male; Mice; Tumor Cells, Cultured; Uridine Triphosphate | 1994 |
Nucleoside transport inhibition and platelet aggregation in human blood: R75231 and its enantiomers, draflazine and R88016.
Topics: Adenosine; Adenosine Diphosphate; Binding Sites; Biological Transport; Blood Platelets; Erythrocytes; Humans; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Radioligand Assay; Stereoisomerism; Thioinosine | 1994 |
Evaluation of cold reperfusion as an indicator of viability in stored organs: a 31P NMR study in rat liver.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Allopurinol; Animals; Cold Temperature; Colloids; Gelatin; Glutathione; Hydrogen-Ion Concentration; In Vitro Techniques; Insulin; Liver; Magnetic Resonance Spectroscopy; Male; Organ Preservation; Organ Preservation Solutions; Perfusion; Phosphates; Raffinose; Rats; Rats, Wistar; Solutions; Time Factors | 1994 |
Intrinsic tryptophan fluorescence of bovine liver adenosine kinase, characterization of ligand binding sites and conformational changes.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Kinase; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Binding Sites; Cattle; Electrophoresis, Polyacrylamide Gel; Ligands; Liver; Magnesium Chloride; Molecular Weight; Protein Conformation; Spectrometry, Fluorescence; Tryptophan | 1994 |
Characterization of an ATP diphosphohydrolase activity (APYRASE, EC 3.6.1.5) in rat blood platelets.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Blood Platelets; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Male; Rats; Rats, Wistar; Substrate Specificity | 1993 |
Effects of regional inhibition of nitric oxide synthesis in intact porcine hearts.
Topics: Adenosine; Adenosine Diphosphate; Animals; Arginine; Coronary Circulation; Female; Hemodynamics; Hyperemia; Male; Myocardial Ischemia; Myocardium; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Oxygen Consumption; Swine; Time Factors | 1994 |
2-Fluoroadenosine uptake by erythrocytes and endothelial cells studied by 19F-NMR.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Chromatography, High Pressure Liquid; Endothelium, Vascular; Erythrocytes; Fluorine; Humans; Magnetic Resonance Spectroscopy; Swine | 1994 |
2-Alkynyl derivatives of adenosine-5'-N-ethyluronamide: selective A2 adenosine receptor agonists with potent inhibitory activity on platelet aggregation.
Topics: Adenosine; Adenosine Diphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Chemical Phenomena; Chemistry, Physical; Heart Rate; Hydroxylation; Male; Molecular Structure; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Structure-Activity Relationship; Vasodilation | 1994 |
Purine nucleotide levels in host tissues of Ehrlich ascites tumor-bearing mice in different growth phases of the tumor.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Carcinoma, Ehrlich Tumor; Cell Division; Chromatography, High Pressure Liquid; Female; Guanine Nucleotides; Guanosine; Inosine; Kinetics; Liver; Mice; Mice, Inbred ICR; Muscles; Purine Nucleotides; Time Factors | 1993 |
Evidence that ATP, ADP and AMP are not ligands of the striatal adenosine A2A receptors.
Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Binding, Competitive; Cattle; Corpus Striatum; In Vitro Techniques; Membranes; Phenethylamines; Receptors, Purinergic P1 | 1993 |
Two-dimensional transferred nuclear Overhauser effect spectroscopy (TRNOESY) studies of nucleotide conformations in creatine kinase complexes: effects due to weak nonspecific binding.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Binding Sites; Creatine Kinase; Ligands; Magnetic Resonance Spectroscopy; Muscles; Protein Binding; Protein Conformation; Protons; Rabbits; Thermodynamics | 1993 |
Coordinated inhibition of actin-induced platelet aggregation by plasma gelsolin and vitamin D-binding protein.
Topics: Actins; Adenosine; Adenosine Diphosphate; Animals; Apyrase; Aspirin; Dose-Response Relationship, Drug; Gelsolin; Humans; Kinetics; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Vitamin D-Binding Protein | 1993 |
Effect of idebenone on adenosine outflow and adenine nucleotide level in hippocampal slices under ischemia-like conditions.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Benzoquinones; Brain Ischemia; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Hippocampus; In Vitro Techniques; Inosine; Male; Rats; Rats, Wistar; Ubiquinone | 1993 |
Mg2+ affects the binding of ADP but not ATP to 3-phosphoglycerate kinase. Correlation between equilibrium dialysis binding and enzyme kinetic data.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Binding Sites; Dialysis; Kinetics; Magnesium; Molecular Conformation; Muscles; Phosphoglycerate Kinase; Swine | 1993 |
Activation of mast cell K+ channels through multiple G protein-linked receptors.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Barium; Barium Compounds; Chlorides; Dimaprit; Electrophysiology; GTP-Binding Proteins; Guanine Nucleotides; Kinetics; Leukemia, Basophilic, Acute; Mast Cells; Nitrendipine; Potassium Channels; Rats; Serotonin; Tumor Cells, Cultured | 1993 |
Effect of standard-dose versus high-dose epinephrine on myocardial high-energy phosphates during ventricular fibrillation and closed-chest CPR.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Biopsy; Blood Gas Analysis; Cardiopulmonary Resuscitation; Chromatography, High Pressure Liquid; Clinical Protocols; Disease Models, Animal; Drug Evaluation, Preclinical; Epinephrine; Guanosine Triphosphate; Heart Arrest; Hemodynamics; Injections, Intravenous; Inosine; Inosine Monophosphate; Myocardium; Phosphocreatine; Swine; Ventricular Fibrillation | 1993 |
Intracellular formation and release of adenosine from rat hippocampal slices evoked by electrical stimulation or energy depletion.
Topics: Adenosine; Adenosine Diphosphate; Animals; Electric Stimulation; Energy Metabolism; Hippocampus; Homocysteine; In Vitro Techniques; Intracellular Membranes; Male; Purines; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine | 1993 |
Comparison of two experimental models for assessment of cardiac preservation.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Allopurinol; Animals; Cardioplegic Solutions; Cell Survival; Cryopreservation; Energy Metabolism; Glutathione; Graft Survival; Heart Transplantation; Humans; Insulin; Myocardium; Organ Preservation; Organ Preservation Solutions; Raffinose; Rats; Rats, Sprague-Dawley; Solutions; Tetralogy of Fallot | 1993 |
Effect of P2Y agonists on adenosine transport in cultured chromaffin cells.
Topics: Adenosine; Adenosine Diphosphate; Adenylyl Imidodiphosphate; Adrenal Medulla; Animals; Biological Transport; Bradykinin; Carbachol; Cattle; Cells, Cultured; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Kinetics; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Purinergic; Thionucleotides | 1993 |
Manipulation of endogenous adenosine in the rat prepiriform cortex modulates seizure susceptibility.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Kinase; Animals; Bicuculline; Cerebral Cortex; Male; Pentostatin; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Seizures; Theophylline; Thioinosine | 1993 |
Cytolytic effects and biochemical changes induced by extracellular ATP to isolated hepatocytes.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cell Survival; Deferoxamine; Guanosine Triphosphate; L-Lactate Dehydrogenase; Liver; Male; Phosphorylases; Protein Biosynthesis; Rats; Rats, Wistar; Time Factors; Uridine Triphosphate | 1993 |
Influence of additional warm ischemia on rat hepatic energy metabolism: a comparison of University of Wisconsin and HTK protection.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Allopurinol; Animals; Energy Metabolism; Glucose; Glutathione; Insulin; Ischemia; Liver; Male; Mannitol; Organ Preservation Solutions; Potassium Chloride; Procaine; Raffinose; Rats; Rats, Sprague-Dawley; Solutions; Temperature | 1993 |
Assessment of purine metabolism in human renal transplantation.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Biopsy; Cold Temperature; Energy Metabolism; Humans; Hypoxanthine; Hypoxanthines; Inosine; Kidney Cortex; Kidney Transplantation; Kidney Tubular Necrosis, Acute; Organ Preservation; Purines; Reperfusion | 1993 |
Functional and biochemical effects of a K(+)-ionophore on the isolated perfused rat heart.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Heart; Inosine; Inosine Monophosphate; Lactates; Male; Myocardium; Perfusion; Phosphofructokinase-1; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Rheology; Valinomycin | 1993 |
Altered cellular signalling and decreased platelet sensitivity to adenosine in insulin-dependent diabetic patients with proliferative retinopathy.
Topics: Adenosine; Adenosine Diphosphate; Adenosine-5'-(N-ethylcarboxamide); Binding Sites; Blood Platelets; Cell Membrane; Colforsin; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Epoprostenol; Female; GTP-Binding Proteins; Humans; Middle Aged; Platelet Aggregation; Receptors, Purinergic; Signal Transduction | 1993 |
Negative cooperativity in the binding of nucleotides to Escherichia coli replicative helicase DnaB protein. Interactions with fluorescent nucleotide analogs.
Topics: Adenosine; Adenosine Diphosphate; Bacterial Proteins; Binding, Competitive; DNA Helicases; DnaB Helicases; Escherichia coli; Fluorescent Dyes; Macromolecular Substances; Nucleotides; ortho-Aminobenzoates; Spectrometry, Fluorescence; Thermodynamics | 1993 |
Simultaneous determination of nerve-induced adenine nucleotides and nucleosides released from rabbit pulmonary artery.
Topics: Acetaldehyde; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Chromatography, High Pressure Liquid; Drug Stability; Electric Stimulation; Fluorescent Dyes; In Vitro Techniques; Male; Nucleosides; Pulmonary Artery; Rabbits; Reference Standards; Reproducibility of Results; Vidarabine | 1993 |
Regional difference of endogenous ATP release in the pulmonary artery of rabbits.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Animals; In Vitro Techniques; Male; Methoxamine; Pulmonary Artery; Rabbits | 1995 |
ATP-induced increase in intracellular Ca2+ concentration in the cultured marginal cell of the stria vascularis of guinea-pigs.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cell Size; Cells, Cultured; Desmin; Enzyme Inhibitors; Fluorometry; Fura-2; Guinea Pigs; Immunohistochemistry; Keratins; Microscopy, Electron; Ouabain; Sodium; Sodium-Potassium-Exchanging ATPase; Stria Vascularis; Vimentin | 1995 |
Disposition of diadenosine 5',5"'-P1,P4-tetraphosphate (Ap4A) in rats.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Dinucleoside Phosphates; Half-Life; Injections, Intravenous; Male; Rats; Rats, Wistar | 1995 |
[The effect of ADP on the contractile activity of guinea pig intestinal smooth muscle].
Topics: Adenosine; Adenosine Diphosphate; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Anaphylaxis; Animals; Diphenhydramine; Epinephrine; Female; Guinea Pigs; In Vitro Techniques; Male; Metaproterenol; Muscle Contraction; Muscle, Smooth; Naphazoline | 1995 |
Preservation of insulin secretory responses to P2 purinoceptor agonists in Zucker diabetic fatty rats.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Analysis of Variance; Animals; Blood Glucose; Body Weight; Calcium; Diabetes Mellitus; Diabetes Mellitus, Type 2; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Obesity; Perfusion; Potassium Chloride; Purinergic P2 Receptor Agonists; Rats; Rats, Wistar; Rats, Zucker; Reference Values; Thionucleotides; Time Factors | 1996 |
Release of oxygen metabolites from chemoattractant-stimulated neutrophils is inhibited by resting platelets: role of extracellular adenosine and actin polymerization.
Topics: Actin Cytoskeleton; Actins; Adenine; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Biological Factors; Blood Platelets; Cells, Cultured; Chemotactic Factors; Chemotaxis, Leukocyte; Culture Media, Conditioned; Cytochalasin B; Humans; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Purinergic P1 Receptor Antagonists; Reactive Oxygen Species; Receptors, Purinergic P1; Respiratory Burst; Theophylline | 1996 |
Biphasic effect of ATP on neutrophil functions mediated by P2U and adenosine A2A receptors.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Calcium; Dose-Response Relationship, Drug; Humans; Inositol 1,4,5-Trisphosphate; Leukocyte Elastase; Neutrophils; Pancreatic Elastase; Receptors, Purinergic P1; Receptors, Purinergic P2; Uridine Triphosphate | 1996 |
Nucleotide-binding sites in F1-ATPase: different pockets for different types of nucleotide analogues.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Binding Sites; Dinucleoside Phosphates; Diphosphates; Kinetics; Mitochondria; Molecular Structure; Protein Conformation; Proton-Translocating ATPases | 1995 |
Pulmonary vascular smooth muscle relaxation by cAMP-mediated pathways.
Topics: Adenosine; Adenosine Diphosphate; Alprostadil; Animals; Cyclic AMP; Dimaprit; Dose-Response Relationship, Drug; Isoproterenol; Male; Muscle, Smooth, Vascular; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-2; Vasodilation | 1996 |
Endothelium-dependent relaxation of the canine pulmonary artery is preserved after prolonged preservation with University of Wisconsin solution.
Topics: Acetylcholine; Adenosine; Adenosine Diphosphate; Allopurinol; Animals; Dogs; Endothelium, Vascular; Glutathione; Insulin; Muscle Relaxation; Muscle, Smooth, Vascular; Organ Preservation; Organ Preservation Solutions; Phenylephrine; Pulmonary Artery; Raffinose | 1996 |
Regulation of proliferation of LLC-MK2 cells by nucleosides and nucleotides: the role of ecto-enzymes.
Topics: 5'-Nucleotidase; Acid Anhydride Hydrolases; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Alkaline Phosphatase; Animals; Cell Division; Cell Line; Cell Line, Transformed; Dinucleoside Phosphates; Dipyridamole; Enzyme Inhibitors; HeLa Cells; Humans; Levamisole; Nucleoside-Triphosphatase; Nucleosides; Nucleotides; Suramin; Thymidine; Triazines | 1996 |
Characterisation of a recombinant P2Y purinoceptor.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Animals; Brain; Cell Line; Electrophysiology; Inositol Phosphates; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Recombinant Proteins; Suramin; Thionucleotides; Triazines; Uridine Triphosphate; Xenopus | 1995 |
Inhibition of ADP-induced platelet activation by 7-chloro-4-nitrobenz-2-oxa-1,3-diazole: covalent modification of aggregin, a putative ADP receptor.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 4-Chloro-7-nitrobenzofurazan; Adenosine; Adenosine Diphosphate; Blood Platelets; Calcimycin; Calcium; Cell Aggregation; Cell Size; Collagen; Cyclic AMP; Fibrinogen; Humans; Platelet Activation; Platelet Membrane Glycoproteins; Prostaglandin Endoperoxides, Synthetic; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2; Time Factors | 1996 |
ATP induces release of newly synthesized dopamine in the rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; alpha-Methyltyrosine; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Corpus Striatum; Dopamine; Homovanillic Acid; Kinetics; Male; Methyltyrosines; Microdialysis; Neurons; omega-Conotoxin GVIA; Peptides; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Reserpine; Suramin; Tetrodotoxin; Xanthines | 1996 |
Inactivation of ecto-ATPase activity of rat brain synaptosomes.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Alkaline Phosphatase; Animals; Brain; Ca(2+) Mg(2+)-ATPase; Concanavalin A; Enzyme Activation; Enzyme Inhibitors; Hydrolysis; Kinetics; Phosphates; Phosphorylation; Rats; Rats, Wistar; Synaptosomes | 1996 |
Ischemic preconditioning: bioenergetic and metabolic changes and the role of endogenous adenosine.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Coronary Circulation; Energy Metabolism; Heart; Hydrogen-Ion Concentration; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Magnesium; Magnetic Resonance Spectroscopy; Male; Microdialysis; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Oxygen Consumption; Phosphates; Phosphocreatine; Phosphorus; Rabbits; Rats; Rats, Sprague-Dawley; Species Specificity; Time Factors; Ventricular Function, Left | 1996 |
Effect of extracellular adenosine 5'-triphosphate on Ca2+ efflux from freshly isolated adult rat cardiomyocytes.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Dose-Response Relationship, Drug; Heart; Male; Myocardium; Rats; Rats, Sprague-Dawley | 1996 |
The isolation from human seminal plasma of a new form of soluble 5'-nucleotidase.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Enzyme Stability; Humans; Hydrogen-Ion Concentration; Isoenzymes; Male; Metals; Molecular Weight; Nucleotidases; Phosphates; Semen; Solubility; Substrate Specificity; Temperature | 1996 |
Defective ATP-dependent mucin secretion by cystic fibrosis pancreatic epithelial cells.
Topics: Adenocarcinoma; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adult; Antigens; Calcium; Carbachol; Cell Line; Colforsin; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelium; Humans; Immunoassay; Mucins; Pancreatic Neoplasms; Receptors, Purinergic P2; Transfection; Tumor Cells, Cultured; Vasoactive Intestinal Peptide | 1996 |
Regulation by purinergic agonists of zinc uptake by rat submandibular glands.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Calcium Channels; Carbachol; Cardiotonic Agents; Dose-Response Relationship, Drug; Fluorescent Dyes; Fura-2; Indicators and Reagents; Isoproterenol; Lanthanum; Lithium; Male; Nickel; Potassium; Purinergic Agonists; Rats; Rats, Wistar; Rosaniline Dyes; Sodium; Submandibular Gland; Zinc | 1995 |
Cerebral energy metabolism during severe ischemia of varying duration and following reperfusion.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Blood Pressure; Cerebral Cortex; Energy Metabolism; Inosine; Ischemic Attack, Transient; Male; Rats; Rats, Sprague-Dawley; Reperfusion; Time Factors | 1996 |
Preferential release of ATP and its extracellular catabolism as a source of adenosine upon high- but not low-frequency stimulation of rat hippocampal slices.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Electric Stimulation; Energy Metabolism; Enzyme Inhibitors; Hippocampus; In Vitro Techniques; Kinetics; Long-Term Potentiation; Male; Models, Neurological; Neurons; Rats; Rats, Wistar; Time Factors; Tritium | 1996 |
Temporal variations of adenosine metabolism in human blood.
Topics: 5'-Nucleotidase; Acclimatization; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Kinase; Adenosine Monophosphate; Adenosine Triphosphate; Adenosylhomocysteinase; Adult; Analysis of Variance; Blood Glucose; Circadian Rhythm; Humans; Hydrolases; Hypoxanthine; Inosine; Lactates; Male; Uric Acid | 1996 |
Studies on the roles of ATP, adenosine and nitric oxide in mediating muscle vasodilatation induced in the rat by acute systemic hypoxia.
Topics: 5'-Nucleotidase; Acute Disease; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Enzyme Inhibitors; Hypoxia; Male; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxygen Consumption; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Regional Blood Flow; Theophylline; Vasodilation | 1996 |
Effects of oxyhemoglobin on local and propagated vasodilatory responses induced by adenosine, adenosine diphosphate, and adenosine triphosphate in rat cerebral arterioles.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cerebral Arteries; Dose-Response Relationship, Drug; Male; Oxyhemoglobins; Rats; Rats, Sprague-Dawley; Vasodilation | 1996 |
Activation of ecto-5'-nucleotidase by protein kinase C attenuates irreversible cellular injury due to hypoxia and reoxygenation in rat cardiomyocytes.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Cell Hypoxia; Cell Survival; Enzyme Activation; In Vitro Techniques; Male; Methoxamine; Myocardium; Oxygen; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 1996 |
Adenine nucleotide metabolism of the small bowel during preservation by the cavitary two-layer method.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Allopurinol; Animals; Energy Metabolism; Glutathione; Graft Survival; Insulin; Intestinal Mucosa; Intestine, Small; Male; Organ Preservation; Organ Preservation Solutions; Raffinose; Rats; Rats, Inbred Lew; Time Factors; Transplantation, Isogeneic | 1996 |
Small bowel preservation: evaluation of different solutions.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Allopurinol; Animals; Glutathione; Hypertonic Solutions; Insulin; Intestinal Mucosa; Intestine, Small; Ischemia; Isotonic Solutions; Male; Mesenteric Artery, Superior; Organ Preservation; Organ Preservation Solutions; Raffinose; Rats; Rats, Inbred Lew; Reperfusion; Reperfusion Injury; Ringer's Lactate; Time Factors | 1996 |
Direct measurement of the release of ATP and its major metabolites from the nerve fibres of the guinea-pig taenia coli.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Analysis of Variance; Animals; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Colon; Electric Stimulation; Enteric Nervous System; Guinea Pigs; Muscle, Smooth; Nerve Fibers; Neuropeptides; Neurotransmitter Agents; Nicardipine; Pituitary Adenylate Cyclase-Activating Polypeptide; Purines; Tetrodotoxin | 1996 |
Evidence for the differential release of the cotransmitters ATP and noradrenaline from sympathetic nerves of the guinea-pig vas deferens.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adrenal Medulla; Animals; Cattle; Cells, Cultured; Chromaffin Cells; Chromatography, High Pressure Liquid; Dimethylphenylpiperazinium Iodide; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Kinetics; Male; Muscle, Smooth; Norepinephrine; Potassium Chloride; Sympathetic Nervous System; Vas Deferens | 1996 |
Bactericidal effect of ADP and acetic acid on Bacillus subtilis.
Topics: Acetic Acid; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Bacillus subtilis; Hydrochloric Acid; Hydrogen-Ion Concentration; Osmolar Concentration | 1997 |
Evidence for the involvement of ecto-5'-nucleotidase (CD73) in drug resistance.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Doxorubicin; Drug Resistance, Multiple; Humans; Mice; Rhodamines; RNA, Messenger; Tumor Cells, Cultured | 1996 |
Contribution of cytosolic and membrane-bound 5'-nucleotidases to cardiac adenosine production.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Cell Membrane; Cytosol; Dogs; Hydrogen-Ion Concentration; Hydrolysis; Magnesium Chloride; Myocardium; Substrate Specificity | 1996 |
Kinetics of extracellular ATP hydrolysis by microvascular endothelial cells from rat heart.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Apyrase; Cells, Cultured; Dipyridamole; Endothelium, Vascular; Enzyme Inhibitors; Female; Hydrolysis; Kinetics; Microcirculation; Nucleotidases; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 1995 |
Influence of UW solution on in vitro platelet aggregability.
Topics: Adenosine; Adenosine Diphosphate; Adult; Allopurinol; Female; Glutathione; Humans; In Vitro Techniques; Insulin; Male; Organ Preservation Solutions; Platelet Aggregation; Raffinose | 1996 |
Interplay between milrinone and adenosine in the inhibition of human platelet response.
Topics: Adenosine; Adenosine Diphosphate; Adult; Blood Platelets; Collagen; Cyclic AMP; Dipyridamole; Epinephrine; Humans; In Vitro Techniques; Male; Milrinone; Phosphodiesterase Inhibitors; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyridones; Theophylline | 1996 |
Dissociation between adenosine release, MVO2, and energy status in working guinea pig hearts.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adrenergic beta-Agonists; Animals; Carbon; Dobutamine; Energy Metabolism; Guinea Pigs; Heart; Magnetic Resonance Spectroscopy; Myocardium; Oxygen; Oxygen Consumption; Perfusion; Substrate Specificity | 1997 |
A source of adenosine involved in cardiovascular responses to defense area stimulation.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Cardiovascular System; Defense Mechanisms; Electric Stimulation; Enzyme Inhibitors; Femoral Artery; Heart Rate; Male; Medulla Oblongata; Microinjections; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Solitary Nucleus | 1997 |
ADP-mimicking platelet aggregation caused by rugosin E, an ellagitannin isolated from Rosa rugosa Thunb.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Animals; Apyrase; Blood Platelets; Calcium; Creatine Kinase; Humans; Hydrolyzable Tannins; Inositol Phosphates; Phosphocreatine; Plant Extracts; Plants, Medicinal; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Tannins; Thromboxane B2 | 1997 |
Functional expression of a P2T ADP receptor in Xenopus oocytes injected with megakaryocyte (CMK 11-5) RNA.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Animals; Blood Platelets; Calcium; Cell Line; Gene Expression; Humans; Megakaryocytes; Microinjections; Oocytes; Receptors, Purinergic P2; Signal Transduction; Xenopus laevis | 1997 |
Binding of divalent magnesium by Escherichia coli phosphoribosyl diphosphate synthetase.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Calcium; Escherichia coli; Kinetics; Magnesium; Pentosephosphates; Protein Binding; Ribose-Phosphate Pyrophosphokinase; Ribosemonophosphates | 1997 |
Vesnarinone limits infarct size via adenosine-dependent mechanisms in the canine heart.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Cardiotonic Agents; Dipyridamole; Dogs; Enzyme Activation; Enzyme Inhibitors; Infusions, Intra-Arterial; Ion Channel Gating; Myocardial Infarction; Myocardial Reperfusion Injury; Potassium Channels; Pyrazines; Quinolines; Receptors, Purinergic P1; Theophylline | 1997 |
Effects of an inhibitor of adenosine deaminase, deoxycoformycin, and of nucleoside transport, propentofylline, on post-ischemic recovery of adenine nucleotides in rat brain.
Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Brain; Ischemic Attack, Transient; Male; Microwaves; Pentostatin; Rats; Rats, Sprague-Dawley; Reperfusion; Time Factors; Xanthines | 1996 |
Electrophysiological-anatomic correlates of ATP-triggered vagal reflex in the dog. IV. Role of LV vagal afferents.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Afferent Pathways; Animals; Coronary Vessels; Dogs; Female; Heart; Heart Atria; Heart Rate; Injections, Intra-Arterial; Male; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Reflex; Vagotomy; Vagus Nerve | 1997 |
ATP-activated cationic current in rabbit sino-atrial node cells.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cations; Chloride Channels; Electrophysiology; Ion Channels; Rabbits; Sinoatrial Node | 1997 |
Purine and pyrimidine nucleotide receptors in the apical membranes of equine cultured epithelia.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Bicarbonates; Binding, Competitive; Cells, Cultured; Chelating Agents; Chlorides; Egtazic Acid; Epithelium; Horses; Pertussis Toxin; Receptors, Purinergic; Sweat Glands; Uridine Triphosphate; Vasodilator Agents; Virulence Factors, Bordetella | 1997 |
Roles of purine nucleotides and adenosine in enhancing NOS II gene expression in interleukin-1 beta-stimulated rat vascular smooth muscle cells.
Topics: Adenosine; Adenosine Diphosphate; Animals; Cells, Cultured; Gene Expression Regulation; Interleukin-1; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitrites; Purine Nucleotides; Rats; Receptors, Purinergic P1; Transcription, Genetic | 1997 |
P2-receptor-mediated inhibition of noradrenaline release in the rat hippocampus.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Electric Stimulation; Hippocampus; In Vitro Techniques; Isotope Labeling; Male; Norepinephrine; Phenethylamines; Rats; Rats, Wistar; Receptors, Purinergic P2; Thionucleotides; Triazines; Tritium; Xanthines; Yohimbine | 1997 |
Effect of erythrocytes and prostacyclin production in the effect of fructose and sorbitol on platelet activation in human whole blood in vitro.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine; Adenosine Diphosphate; Adult; Animals; Aorta; Blood Glucose; Blood Platelets; Collagen; Diabetic Angiopathies; Epoprostenol; Erythrocytes; Fructose; Humans; Hyperglycemia; In Vitro Techniques; Lipid Peroxidation; Male; Platelet Activation; Platelet Aggregation; Rats; Rats, Wistar; Sorbitol; Thromboxane B2 | 1997 |
Purification and kinetic characterization of Haemophilus parasuis malate dehydrogenase.
Topics: Adenosine; Adenosine Diphosphate; Chromatography, Gel; Coenzymes; Dimerization; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Haemophilus; Kinetics; Malate Dehydrogenase; Malates; Molecular Weight; NAD; Nicotinyl Alcohol; Protein Denaturation; Substrate Specificity; Temperature | 1997 |
Evidence against a major role of adenosine in oxygen-dependent regulation of erythropoietin in rats.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Animals; Antihypertensive Agents; Carbon Monoxide; Dipyridamole; Diuretics; Drug Synergism; Enzyme Inhibitors; Erythropoietin; Gene Expression; Hypoxia; Kidney; Male; Oxygen; Phenethylamines; Phosphodiesterase Inhibitors; Piperazines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; RNA, Messenger; Theophylline; Vasodilator Agents; Xanthines | 1997 |
Differences in the distribution of responses to ATP and acetylcholine between outer hair cells of rat and guinea pig.
Topics: Acetylcholine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Guinea Pigs; Hair Cells, Auditory, Outer; Ion Channels; Meglumine; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Vasodilator Agents; Vestibular Nucleus, Lateral | 1997 |
Adenosine triphosphate degradation products after oxidative stress and metabolic dysfunction in cultured retinal cells.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Cell Hypoxia; Cells, Cultured; Chick Embryo; Enzyme Inhibitors; Glucose; Hypoxanthine; Inosine; Iodoacetates; Iodoacetic Acid; Ischemia; Kinetics; Oligomycins; Oxidative Stress; Retina; Thioinosine | 1997 |
Stimulation of alpha 1-adrenoceptors and protein kinase C-mediated activation of ecto-5'-nucleotidase in rat hearts in vivo.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Alkaloids; Analysis of Variance; Animals; Benzophenanthridines; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Female; Heart; Kinetics; Male; Methoxamine; Microdialysis; Myocardium; Norepinephrine; Perfusion; Phenanthridines; Prazosin; Protein Kinase C; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1 | 1997 |
Hydrolysis of extracellular adenine nucleotides by equine epidydimal spermatozoa.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Apyrase; Epididymis; Horses; Hydrolysis; Kinetics; Male; Nucleotidases; Nucleotides; Spermatozoa; Time Factors | 1997 |
Xanthine affects [Ca2+]i and contractile responses of ventricular cardiocytes to electrical stimulation.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cell Polarity; Cells, Cultured; Chick Embryo; Cytosol; Heart; Heart Ventricles; Kinetics; Myocardial Contraction; Myocardium; Receptors, Purinergic P1; Receptors, Purinergic P2; Superoxides; Xanthine; Xanthines | 1997 |
Endothelial-mediated dilations of rat middle cerebral arteries by ATP and ADP.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cerebral Arteries; Endothelium, Vascular; Kinetics; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Purinergic P2 Receptor Agonists; Rats; Receptors, Purinergic P2Y2; Thionucleosides; Uridine Triphosphate; Vasodilation | 1997 |
Structure-based analysis of catalysis and substrate definition in the HIT protein family.
Topics: Acid Anhydride Hydrolases; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Binding Sites; Catalysis; Crystallography, X-Ray; Dimerization; Dinucleoside Phosphates; Hydrogen Bonding; Neoplasm Proteins; Nerve Tissue Proteins; Protein Structure, Secondary; Proteins; Structure-Activity Relationship; Substrate Specificity; Tungsten Compounds | 1997 |
Study of the substrate-binding properties of bovine liver adenosine kinase and inhibition by fluorescent nucleoside analogues.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Kinase; Adenosine Triphosphate; Animals; Binding Sites; Binding, Competitive; Cattle; Enzyme Inhibitors; Fluorescent Dyes; Liver; Nucleosides; Nucleotides; ortho-Aminobenzoates; Polyphosphates; Protein Binding; Spectrometry, Fluorescence | 1997 |
Purinergic transmitters inhibit bone formation by cultured osteoblasts.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Bone Development; Calcium; Cattle; Cells, Cultured; Drug Synergism; Osteoblasts; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Proteins; Purinergic Agonists; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thionucleotides; Uridine Triphosphate | 1997 |
The role of cyclic AMP as a precursor of extracellular adenosine in the rat hippocampus.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Animals; Colforsin; Cyclic AMP; Diterpenes; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Guanosine Monophosphate; Hippocampus; In Vitro Techniques; Male; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theophylline | 1997 |
Protein, not adenosine or adenine nucleotides, mediates platelet decrease in endothelial permeability.
Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Blood Platelets; Blood Proteins; Cattle; Cell Membrane Permeability; Cells, Cultured; Culture Media, Conditioned; Endothelium, Vascular; Humans; Pulmonary Artery; Xanthines | 1997 |
A novel phospholipase C- and cAMP-independent positive inotropic mechanism via a P2 purinoceptor.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Chick Embryo; Cyclic AMP; Enzyme Inhibitors; Estrenes; Myocardial Contraction; Myocardium; Phosphatidylinositols; Purinergic P2 Receptor Agonists; Pyrrolidinones; Receptors, Purinergic P2; Type C Phospholipases; Uridine Triphosphate | 1997 |
Prolonged hypothermic cardiac storage with histidine-tryptophan-ketoglutarate solution: comparison with glucose-insulin-potassium and University of Wisconsin solutions.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Allopurinol; Animals; Body Water; Glucose; Glutathione; Heart; Heart Arrest, Induced; In Vitro Techniques; Insulin; Male; Mannitol; Myocardium; Organ Preservation; Organ Preservation Solutions; Potassium; Potassium Chloride; Procaine; Raffinose; Rats; Rats, Wistar; Time Factors | 1997 |
Demonstration of an extracellular ATP-binding site in NCAM: functional implications of nucleotide binding.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Affinity Labels; Animals; Binding Sites; Cell Membrane; Chromatography, Ion Exchange; Hydrolysis; Neural Cell Adhesion Molecules; Rats; Rats, Wistar; Substrate Specificity | 1997 |
Pharmacologic characteristics of rabbit esophageal muscularis mucosae in vitro.
Topics: Acetylcholine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adrenergic Agonists; Adrenergic beta-Agonists; Animals; Bradykinin; Electric Stimulation; Esophagus; Histamine; In Vitro Techniques; Isoproterenol; Male; Muscle, Smooth; Norepinephrine; Phentolamine; Propranolol; Prostaglandins; Rabbits; Receptors, Purinergic; Substance P | 1997 |
Effects of ischemic preconditioning on contractile and metabolic function during hypoperfusion in dogs.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Blood Flow Velocity; Coronary Circulation; Coronary Vessels; Dogs; Enzyme Inhibitors; Hydrogen-Ion Concentration; Ischemic Preconditioning, Myocardial; Lactic Acid; Myocardial Contraction; Myocardium; Purinergic P1 Receptor Antagonists; Theophylline | 1998 |
Divalent cation dependence and inhibition of Schistosoma mansoni ATP diphosphohydrolase by fluorosulfonylbenzoyl adenosine.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Cations; Enzyme Activation; Enzyme Inhibitors; Hydrolysis; Magnesium; Models, Molecular; Schistosoma mansoni | 1998 |
Characterization of purinergic receptor-evoked increases in intracellular Ca2+ transients in isolated human and rodent insulin-secreting cells. Purinergic receptor signalling and [Ca2+]i in human beta-cells.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cadaver; Calcium; Cells, Cultured; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Models, Biological; Receptors, Purinergic; Rodentia; Signal Transduction; Suramin; Tissue Donors; Uridine Triphosphate | 1997 |
Characterization of [3H]AMP binding to rat adipose plasma membranes and its substrate specificity.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adipose Tissue; Animals; Binding Sites; Binding, Competitive; Cell Membrane; Cells, Cultured; Chelating Agents; Edetic Acid; Kinetics; Male; Rats; Rats, Wistar; Substrate Specificity | 1997 |
P2Y- and P2U-mediated increases in internal calcium in single bovine aortic endothelial cells in primary culture.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Cattle; Cells, Cultured; Ion Transport; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Thionucleotides; Uridine Triphosphate | 1997 |
Effect of additional testosterone on purinergic responses in isolated rabbit corpus cavernosum strips.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Nitroprusside; Penile Erection; Penis; Potassium Chloride; Rabbits; Receptors, Purinergic; Testosterone; Vasodilator Agents | 1998 |
P2X receptors in cochlear Deiters' cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cochlea; Colforsin; Dose-Response Relationship, Drug; Enzyme Activation; Guinea Pigs; Patch-Clamp Techniques; Protein Kinases; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Tetradecanoylphorbol Acetate; Thionucleotides; Uridine Triphosphate; Vasodilator Agents; Vestibular Nucleus, Lateral | 1998 |
T. brucei RNA editing: adenosine nucleotides inversely affect U-deletion and U-insertion reactions at mRNA cleavage.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Base Sequence; Cytochrome b Group; Endonucleases; Mutagenesis, Site-Directed; RNA Editing; RNA Ligase (ATP); RNA Nucleotidyltransferases; RNA Precursors; RNA, Protozoan; Trypanosoma brucei brucei | 1998 |
Functional expression of P2U receptors in rat spermatogenic cells: dual modulation of a Ca(2+)-activated K+ channel.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Female; Male; Membrane Potentials; Oocytes; Patch-Clamp Techniques; Polymerase Chain Reaction; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Recombinant Proteins; RNA, Messenger; Spermatogenesis; Testis; Transcription, Genetic; Uridine Triphosphate; Xenopus laevis | 1998 |
Evidence that adenosine diphosphate can activate adenylate cyclase via conversion to adenosine in platelet-rich plasma containing magnesium.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Cyclases; Colforsin; Cyclic AMP; Enzyme Activation; Humans; Iloprost; Magnesium; Platelet Aggregation Inhibitors; Platelet Count; Quinazolines; Receptors, Purinergic P2; Reference Values | 1998 |
Luminal ATP induces K+ secretion via a P2Y2 receptor in rat distal colonic mucosa.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Barium; Biological Transport; Colon; Female; In Vitro Techniques; Intestinal Mucosa; Ion Channels; Male; Membrane Potentials; Polymerase Chain Reaction; Potassium; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Thionucleotides; Uridine Triphosphate | 1998 |
Interstitial ATP level and degradation in control and postmyocardial infarcted rats.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Heart; Hypoxanthine; In Vitro Techniques; Inosine; Intracellular Fluid; Male; Microdialysis; Myocardial Contraction; Myocardial Infarction; Myocardium; Rats; Rats, Wistar; Time Factors; Xanthine | 1998 |
Effects of intracellular N+, M2+ and metabolites on C2+-activated K+ channels in pulmonary and ear arterial smooth muscle cells of the rabbit.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arteries; Calcium; Ear, External; Electrophysiology; In Vitro Techniques; Lactic Acid; Magnesium; Muscle, Smooth, Vascular; Potassium Channels; Pulmonary Artery; Rabbits; Regional Blood Flow; Sodium | 1998 |
Metabolic regulation of endogenous adenosine release from single neurons.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Dinucleoside Phosphates; Drug Administration Routes; Electric Stimulation; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Models, Biological; Neurons; Patch-Clamp Techniques; Purinergic P1 Receptor Antagonists; Pyramidal Cells; Rats; Theophylline; Tubercidin | 1998 |
Long-term supplementation with a high cholesterol diet decreases the release of ATP from the caudal artery in aged rats.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aging; Animals; Arteries; Blood Pressure; Body Weight; Cholesterol; Cholesterol, Dietary; Fatty Acids, Unsaturated; Female; In Vitro Techniques; Norepinephrine; Rats; Rats, Wistar; Tail; Triglycerides | 1998 |
Cardiac function and myocardial energy level after prolonged hypothermic storage.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Allopurinol; Animals; Cardiac Output; Coronary Circulation; Energy Metabolism; Glucose; Glutathione; Heart; In Vitro Techniques; Insulin; Male; Mannitol; Myocardium; Organ Preservation; Organ Preservation Solutions; Potassium; Potassium Chloride; Procaine; Raffinose; Rats; Rats, Wistar | 1998 |
P2 purinoceptor localization along rat nephron and evidence suggesting existence of subtypes P2Y1 and P2Y2.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Calcium Channel Blockers; Gallic Acid; Kidney Glomerulus; Kidney Tubules, Collecting; Male; Nephrons; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Suramin; Thionucleotides; Uridine Triphosphate | 1998 |
Adenosine and ADP prevent apoptosis in cultured rat cerebellar granule cells.
Topics: Adenosine; Adenosine Diphosphate; Animals; Apoptosis; Cells, Cultured; Cerebellum; In Situ Nick-End Labeling; Neurons; Potassium Chloride; Rats; Rats, Wistar; Receptors, Purinergic; Xanthines | 1998 |
ATP inhibition of proliferation of immortalized human fibroblasts is greater than that of normal human diploid fibroblasts.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Diploidy; DNA; Fibroblasts; Humans; Phosphoric Acids | 1998 |
A novel conception for liver preservation at a temperature just above freezing point.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Allopurinol; Animals; DNA; Energy Metabolism; Glutathione; Insulin; L-Lactate Dehydrogenase; Liver; Male; Organ Preservation; Organ Preservation Solutions; Raffinose; Rats; Rats, Wistar; Refrigeration; Reperfusion; Temperature; Time Factors | 1999 |
Occurrence of prostasome-like membrane vesicles in equine seminal plasma.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Horses; Male; Microscopy, Electron; Organelles; Semen; Sperm Motility | 1998 |
Ca2+ response of rat mesangial cells to ATP analogues.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Glomerular Mesangium; Rats; Rats, Sprague-Dawley; Thionucleotides; Uridine Triphosphate | 1999 |
Ca2+-permeable P2X receptor channels in cultured rat retinal ganglion cells.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Kinetics; Membrane Potentials; Patch-Clamp Techniques; Rats; Receptors, Purinergic P2; Regression Analysis; Retinal Ganglion Cells; Suramin | 1999 |
Photoaffinity labeling of brain glutamate dehydrogenase isoproteins with an azido-ADP.
Topics: Adenosine; Adenosine Diphosphate; Amino Acid Sequence; Animals; Azides; Brain; Catalytic Domain; Cattle; Enzyme Activation; Glutamate Dehydrogenase; Humans; Isoenzymes; Mice; Molecular Sequence Data; Photoaffinity Labels; Rats; Trypsin | 1999 |
P2 purinoceptors contribute to ATP-induced inhibition of L-type Ca2+ current in rabbit atrial myocytes.
Topics: 1-Methyl-3-isobutylxanthine; 5'-Nucleotidase; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Calcium-Transporting ATPases; Colforsin; Cyclic AMP; Enzyme Inhibitors; Isoproterenol; Myocardium; Patch-Clamp Techniques; Pertussis Toxin; Potassium Channels; Potassium Channels, Voltage-Gated; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rabbits; Receptors, Purinergic P2; Shal Potassium Channels; Suramin; Virulence Factors, Bordetella; Xanthines | 1999 |
AMP deaminase in piglet cardiac myocytes: effect on nucleotide metabolism during ischemia.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; AMP Deaminase; Animals; Animals, Newborn; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Carcinogens; Carotenoids; Cells, Cultured; Cyclic AMP; Energy Metabolism; Enzyme Activation; Heart Ventricles; Ischemic Preconditioning; Muscle Fibers, Skeletal; Myocardial Ischemia; Myocardium; Oxygenases; Phosphodiesterase Inhibitors; Swine; Tetradecanoylphorbol Acetate; Uncoupling Agents | 1999 |
Detection of conformational changes along the kinetic pathway of protein kinase A using a catalytic trapping technique.
Topics: Adenosine; Adenosine Diphosphate; Affinity Labels; Catalysis; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Kinetics; Magnesium; Models, Chemical; Oligopeptides; Phosphopeptides; Protein Conformation; Spectrophotometry | 1999 |
[Platelet activation in cardiology: methods, indications and therapeutic perspectives].
Topics: Adenosine; Adenosine Diphosphate; Antigens, CD; Blood Platelets; CD40 Ligand; Coronary Disease; Dipyridamole; Humans; In Vitro Techniques; Ligands; Membrane Glycoproteins; P-Selectin; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Membrane Glycoproteins; Reference Values; Tetraspanin 30; Theophylline | 1999 |
Immunologically distinct isoforms of ecto-5'-nucleotidase in nerve terminals of different areas of the rat hippocampus.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Extracellular Space; Hippocampus; Immune Sera; Immunologic Techniques; Isoenzymes; Kinetics; Nerve Endings; Rabbits; Rats; Synaptosomes; Tissue Distribution | 2000 |
Breakdown of extracellular ATP by the prostatic and epididymal ends of the guinea pig vas deferens.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Epididymis; Extracellular Space; Guinea Pigs; In Vitro Techniques; Male; Prostate; Time Factors; Vas Deferens | 2000 |
Heart preservation in HTK solution: role of coronary vasculature in recovery of cardiac function.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Allopurinol; Animals; Aorta; Blood Pressure; Cardiac Output; Cardioplegic Solutions; Cold Temperature; Coronary Vessels; Glucose; Glutathione; Heart Arrest, Induced; Heart Rate; Heart Transplantation; Hypertonic Solutions; Insulin; Male; Mannitol; Myocardial Contraction; Myocardium; Nitroprusside; Organ Preservation; Organ Preservation Solutions; Potassium Chloride; Procaine; Raffinose; Rats; Rats, Wistar; Recovery of Function; Regional Blood Flow; Vasodilator Agents; Ventricular Function, Left; Ventricular Pressure | 2000 |
Reserpine attenuates interstitial adenosine-mediated activation of ecto-5'-nucleotidase in rat hearts in vivo.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adrenergic Uptake Inhibitors; Animals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Activation; Heart; Male; Microdialysis; Myocardium; Norepinephrine; Perfusion; Phosphorylation; Rats; Rats, Wistar; Reserpine; Stellate Ganglion; Tyramine | 2000 |
Complex hippocampal responses to ATP: fade due to nucleotidase inhibition and P2-receptor-mediated adenosine release.
Topics: 5'-Nucleotidase; Action Potentials; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Enzyme Inhibitors; Hippocampus; Male; Nerve Tissue Proteins; Rats; Rats, Wistar; Receptors, Purinergic P2; Suramin; Theophylline | 2000 |
Adenosine-derived non-phosphate antagonists for P2Y(1) purinoceptors.
Topics: Adenosine; Adenosine Diphosphate; Aspartic Acid; Astrocytoma; Dose-Response Relationship, Drug; Humans; Phosphates; Phosphatidylinositols; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Thionucleotides; Tumor Cells, Cultured | 2000 |
Role of A(2A)-adenosine receptor activation for ATP-mediated coronary vasodilation in guinea-pig isolated heart.
Topics: Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Coronary Vessels; Glyburide; Guinea Pigs; NG-Nitroarginine Methyl Ester; Perfusion; Receptors, Purinergic P1; Thionucleotides; Vasodilation | 2000 |
Extracellular ATP reduces optically monitored electrical signals in hippocampal slices through metabolism to adenosine.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Electrophysiology; Hippocampus; Organ Culture Techniques; Rats; Rats, Wistar; Signal Transduction; Triazines; Triazoles; Uridine Diphosphate; Xanthines | 2000 |
Effect of dopexamine on intestinal tissue concentrations of high-energy phosphates and intestinal release of purine compounds in endotoxemic rats.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Dopamine; Endotoxemia; Intestinal Mucosa; Intestines; Male; Phosphocreatine; Purines; Random Allocation; Rats; Rats, Wistar | 2000 |
Structural factors that determine the ability of adenosine and related compounds to activate the cardiac ryanodine receptor.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Binding, Competitive; Guanosine Triphosphate; Heart; In Vitro Techniques; Ion Channel Gating; Models, Molecular; Myocardium; Ryanodine Receptor Calcium Release Channel; Sheep; Vasodilator Agents | 2000 |
Diadenosine polyphosphates cause contraction and relaxation in isolated rat resistance arteries.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Dinucleoside Phosphates; Endothelium, Vascular; Epigastric Arteries; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Inbred WKY; Receptors, Purinergic P2; Sympathectomy; Vascular Resistance | 2000 |
Interactions of nucleotide cofactors with the Escherichia coli replication factor DnaC protein.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Bacterial Proteins; Binding, Competitive; Bromides; DNA Replication; Escherichia coli; Escherichia coli Proteins; Fluorescent Dyes; Macromolecular Substances; Magnesium Chloride; Nucleotides; ortho-Aminobenzoates; Ribose; Sodium Chloride; Sodium Compounds; Sugar Phosphates | 2000 |
Intrinsic A(1) adenosine receptor activation during ischemia or reperfusion improves recovery in mouse hearts.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Creatine; Extracellular Space; Heart Function Tests; Heart Rate; Hypoxanthine; In Vitro Techniques; Inosine; Male; Mice; Mice, Inbred C57BL; Microdialysis; Myocardial Ischemia; Myocardium; Phosphocreatine; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Recovery of Function; Reperfusion; Reperfusion Injury; Xanthines | 2000 |
Ischemic-like condition releases norepinephrine and purines from different sources in superfused rat spleen strips.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Hypoxanthine; Inosine; Ischemia; Male; Norepinephrine; Rats; Rats, Wistar; Spleen; Sympathectomy; Sympathetic Nervous System; Sympathomimetics; Tetrodotoxin; Tritium; Vasodilator Agents; Xanthine | 2000 |
Correlation between adenine nucleotide-induced cyclic AMP elevation and extracellular adenosine formation in NG108-15 cells.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cell Membrane; Chromatography, High Pressure Liquid; Cyclic AMP; Enzyme Inhibitors; Extracellular Space; Nucleotidases; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured | 2000 |
Extracellular ATP formation on vascular endothelial cells is mediated by ecto-nucleotide kinase activities via phosphotransfer reactions.
Topics: 5'-Nucleotidase; Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenylate Kinase; Apyrase; Cells, Cultured; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Kinetics; Luminescent Measurements; Membrane Proteins; Nucleoside-Diphosphate Kinase; Phosphates; Phosphorylation; Phosphotransferases (Phosphate Group Acceptor); Substrate Specificity | 2001 |
Simultaneous assessment of ecto- and cytosolic-5'-nucleotidase activities in brain micropunches.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Brain; Cell Membrane; Chromatography, High Pressure Liquid; Cytosol; Enzyme Inhibitors; Magnesium; Male; Nucleotidases; Rats; Rats, Sprague-Dawley | 2000 |
Effects of ATP on intracellular calcium dynamics of the perineurium of peripheral nerve bundles.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Anesthetics, Local; Animals; Antineoplastic Agents; Calcium; Enzyme Inhibitors; Glyburide; Hypoglycemic Agents; Lidocaine; Male; Microscopy, Confocal; Peripheral Nerves; Rats; Rats, Inbred WKY; Sciatic Nerve; Suramin; Tetraethylammonium; Tetrodotoxin; Thapsigargin; Triazines; Uridine Triphosphate | 2000 |
The potential role of adenosine in the pathophysiology of the insulin resistance syndrome.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adipose Tissue; Animals; Coronary Disease; Diabetes Mellitus, Type 2; Erythropoiesis; Fatty Acids; Heart Rate; Hematocrit; Humans; Hyperinsulinism; Hypertrophy; Insulin Resistance; Islets of Langerhans; Mitochondria; Mitochondrial ADP, ATP Translocases; Models, Biological; Natriuresis; Obesity; Oxidative Phosphorylation; Renal Circulation; Risk Factors; Sodium; Superoxides; Sympathetic Nervous System; Uric Acid; Vasodilation | 2001 |
Blood purine and energy status in rats with colitis.
Topics: Acetic Acid; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Biomarkers; Chromatography, High Pressure Liquid; Colitis; Disease Models, Animal; Energy Metabolism; Hemoglobins; Inosine; Male; Peroxidase; Purines; Rats; Rats, Wistar; Time Factors; Uric Acid | 2001 |
[(35)S]GTPgammaS autoradiography reveals a wide distribution of G(i/o)-linked ADP receptors in the nervous system: close similarities with the platelet P2Y(ADP) receptor.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Adrenal Medulla; Animals; Autoradiography; Blood Platelets; Brain; Brain Chemistry; Capillaries; Cell Line; Dithiothreitol; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Glioma; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Heterotrimeric GTP-Binding Proteins; Macromolecular Substances; Magnetic Resonance Spectroscopy; Male; Membrane Proteins; Nerve Tissue Proteins; Neuroglia; Organ Specificity; Rats; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Signal Transduction; Sulfhydryl Reagents; Sulfur Radioisotopes; Thionucleotides; Tumor Cells, Cultured; Uracil Nucleotides; Xanthines | 2001 |
Nicotinamide adenine dinucleotide (NAD) and its metabolites inhibit T lymphocyte proliferation: role of cell surface NAD glycohydrolase and pyrophosphatase activities.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Diphosphate Ribose; Adenosine Monophosphate; ADP Ribose Transferases; Animals; Antigens, Differentiation, T-Lymphocyte; Cell Membrane; Cells, Cultured; Cholera Toxin; Female; Histocompatibility Antigens; Immunosuppressive Agents; Lymphocyte Activation; Male; Membrane Glycoproteins; Mitogens; NAD; NAD+ Nucleosidase; Pertussis Toxin; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide Phospholipase C; Phosphorus Radioisotopes; Poly(ADP-ribose) Polymerases; Pyrophosphatases; Rats; Rats, Inbred BB; Rats, Inbred WF; T-Lymphocytes; Type C Phospholipases; Virulence Factors, Bordetella | 2001 |
Adenosine linking reduced O2 to arteriolar NO release in intestine is not formed from extracellular ATP.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Arterioles; Enzyme Inhibitors; Extracellular Space; Intestine, Small; Male; Nitric Oxide; omega-N-Methylarginine; Oxygen; Rats; Rats, Sprague-Dawley; Vascular Patency; Vasoconstriction; Xanthines | 2001 |
P2Y(11) receptor expression by human lymphocytes: evidence for two cAMP-linked purinoceptors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Cyclic AMP; Dose-Response Relationship, Drug; Gene Expression; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2X7; RNA, Messenger | 2001 |
P2Y(AC)(-)-receptor agonists enhance the proliferation of rat C6 glioma cells through activation of the p42/44 mitogen-activated protein kinase.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cell Division; Dinucleoside Phosphates; Enzyme Activation; Glioma; Hydrolysis; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Purinergic P2 Receptor Agonists; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2; Thionucleotides; Time Factors; Triazines; Tumor Cells, Cultured | 2001 |
Effects of adenosine on thrombosis and thrombolysis in a canine experimental preparation.
Topics: Adenosine; Adenosine Diphosphate; Animals; Arachidonic Acid; Blood Flow Velocity; Carotid Arteries; Carotid Artery Thrombosis; Coronary Circulation; Coronary Thrombosis; Disease Models, Animal; Dogs; Electric Injuries; Female; Fibrinolytic Agents; Male; Platelet Aggregation; Thrombolytic Therapy; Time Factors; Tissue Plasminogen Activator | 2001 |
Activation of the alpha(2A)-adrenoceptor mediates deceleration of the deaggregation component of the response to ADP or 5-HT in human platelets in vitro.
Topics: Adenosine; Adenosine Diphosphate; Adrenergic alpha-2 Receptor Agonists; Adult; Aged; Disintegrins; Epinephrine; Female; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; Heterotrimeric GTP-Binding Proteins; Humans; Male; Membrane Proteins; Middle Aged; Norepinephrine; Platelet Aggregation; Receptor, Serotonin, 5-HT2A; Receptors, Adrenergic, alpha-2; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Receptors, Serotonin; Serotonin; Signal Transduction; Thionucleosides; Viper Venoms | 2001 |
Role of adenosine and P2 receptors in the penile tumescence in anesthetized dogs.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Anesthesia; Animals; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Injections, Intravenous; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Penile Erection; Penis; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Theophylline; Thionucleotides; Triazines; Triazoles | 2001 |
Phenylalanine and phenylpyruvate inhibit ATP diphosphohydrolase from rat brain cortex.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Cerebral Cortex; Hydrolysis; Kinetics; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Presynaptic Terminals; Rats; Rats, Wistar; Synaptosomes | 2001 |
Oxidative stress enhances the production and actions of adenosine in the kidney.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Catalase; Chromatography, High Pressure Liquid; Cyclic N-Oxides; Dimerization; Ditiocarb; Kidney; Kinetics; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Renal Artery; Spin Labels; Superoxide Dismutase; Superoxides; Thioredoxins; Xanthine; Xanthine Oxidase | 2001 |
Extracellular formation and uptake of adenosine during skeletal muscle contraction in the rat: role of adenosine transporters.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Carrier Proteins; Extracellular Space; Membrane Transport Proteins; Muscle Contraction; Muscle, Skeletal; Nucleoside Transport Proteins; Rats; Rats, Wistar; Thioinosine | 2001 |
Regulation of K(ATP) channels by P(2Y) purinoceptors coupled to PIP(2) metabolism in guinea pig ventricular cells.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Androstadienes; Animals; Anti-Arrhythmia Agents; Cytosol; Enzyme Inhibitors; Extracellular Space; Glyburide; Guinea Pigs; Heart Ventricles; Male; Membrane Potentials; Myocardium; Phosphatidylinositol 4,5-Diphosphate; Potassium Channels; Receptors, Purinergic P2; Signal Transduction; Type C Phospholipases; Wortmannin | 2002 |
Effects of inhibitory avoidance training and/or isolated foot-shock on ectonucleotidase activities in synaptosomes of the anterior and posterior cingulate cortex and the medial precentral area of adult rats.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Avoidance Learning; Cerebral Cortex; Electroshock; Hydrolysis; Male; Memory; Nucleotidases; Prefrontal Cortex; Rats; Rats, Wistar; Stress, Psychological; Subcellular Fractions; Synaptosomes | 2002 |
Nucleotide-evoked relaxation of rat vas deferens: possible mechanisms.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cyclic AMP; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscle Relaxation; Nucleotides; Potassium; Rats; Rats, Wistar; Theophylline; Thionucleotides; Vas Deferens | 2002 |
Adenosine increases human platelet levels of cGMP through nitric oxide: possible role in its antiaggregating effect.
Topics: Adenosine; Adenosine Diphosphate; Blood Platelets; Cyclic GMP; Dose-Response Relationship, Drug; Drug Antagonism; Guanylate Cyclase; Humans; Nitric Oxide; Platelet Aggregation; Platelet Aggregation Inhibitors | 2002 |
Inhibition of nitrobenzylthioinosine-sensitive adenosine transport by elevated D-glucose involves activation of P2Y2 purinoceptors in human umbilical vein endothelial cells.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Binding, Competitive; Biological Transport; Cells, Cultured; Endothelium, Vascular; Equilibrative Nucleoside Transporter 1; Glucose; Humans; Membrane Transport Proteins; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; RNA, Messenger; Thioinosine; Umbilical Veins; Uridine Triphosphate | 2002 |
Apoptosis induced by extracellular ATP in the mouse neuroblastoma cell line N1E-115: studies on involvement of P2 receptors and adenosine.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Kinase; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Apoptosis; Mice; Neuroblastoma; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Tumor Cells, Cultured | 2002 |
Complementary role of extracellular ATP and adenosine in ischemic preconditioning in the rat heart.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Coloring Agents; Extracellular Space; Ischemic Preconditioning; Male; Microdialysis; Organic Chemicals; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Receptors, Purinergic P2; Suramin; Theophylline; Ventricular Function, Left; Ventricular Pressure | 2002 |
Cassette mutagenesis and photoaffinity labeling of adenine binding domain of ADP regulatory site within human glutamate dehydrogenase.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Amino Acid Sequence; Animals; Azides; Binding Sites; Glutamate Dehydrogenase; Humans; Mammals; Molecular Sequence Data; Mutagenesis, Insertional; Mutagenesis, Site-Directed; Peptides; Photoaffinity Labels; Protein Structure, Tertiary; Tyrosine | 2002 |
Magnesium reduces myocardial infarct size via enhancement of adenosine mechanism in rabbits.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Analysis of Variance; Animals; Calcium; Drug Synergism; Enzyme Inhibitors; Magnesium; Male; Models, Animal; Myocardial Infarction; Myocardium; Purinergic P1 Receptor Antagonists; Rabbits; Theophylline | 2002 |
Coronary function and adenosine receptor-mediated responses in ischemic-reperfused mouse heart.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Diphosphate; Animals; Caffeine; Coronary Circulation; Heart; Male; Mice; Mice, Inbred C57BL; Models, Animal; Myocardial Contraction; Myocardial Reperfusion Injury; Nitroprusside; Perfusion; Phenethylamines; Purinergic P1 Receptor Antagonists; Vasodilator Agents; Xanthines | 2002 |
Release of ATP during host cell killing by enteropathogenic E. coli and its role as a secretory mediator.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cell Death; Cells, Cultured; Chlorides; Colon; Escherichia coli; Escherichia coli Infections; Humans; Male; Rabbits; Receptors, Purinergic P1 | 2002 |
The importance of impermeant support in small bowel preservation: a morphologic, metabolic and functional study.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Allopurinol; Animals; Glutathione; Insulin; Intestine, Small; Male; Microscopy, Electron, Scanning; Microvilli; Organ Preservation; Organ Preservation Solutions; Raffinose; Rats; Rats, Sprague-Dawley | 2001 |
Inhibition of ADP-triggered blood platelet aggregation by diadenosine polyphosphate analogues.
Topics: Adenosine; Adenosine Diphosphate; Binding Sites; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Nuclear Magnetic Resonance, Biomolecular; Platelet Aggregation; Platelet Aggregation Inhibitors; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Structure-Activity Relationship | 2002 |
Gap junctions between cells expressing connexin 43 or 32 show inverse permselectivity to adenosine and ATP.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Blotting, Western; Cells, Cultured; Chromatography, High Pressure Liquid; Coloring Agents; Connexin 43; Connexins; Gap Junction beta-1 Protein; Gap Junctions; Models, Molecular; Phosphates; Phosphorylation; Protein Binding; Rats; Transfection | 2002 |
Isoflurane-induced facilitation of the cardiac sarcolemmal K(ATP) channel.
Topics: 2,4-Dinitrophenol; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Anesthetics, Inhalation; Animals; Benzopyrans; Dihydropyridines; Guinea Pigs; Heart; Isoflurane; Potassium Channels; Protein Kinase C | 2002 |
Extracellular adenine nucleotides regulate Na+/H+ exchanger NHE3 activity in A6-NHE3 transfectants by a cAMP/PKA-dependent mechanism.
Topics: Adenosine; Adenosine Diphosphate; Animals; Calcium; Cell Line; Cell Membrane; Cyclic AMP; Enzyme Inhibitors; Epithelial Cells; Hydrogen-Ion Concentration; Rats; Signal Transduction; Sodium-Hydrogen Exchangers; Thionucleotides; Transfection; Xenopus laevis | 2002 |
Enzyme kinetics and pharmacological characterization of nucleotidases released from the guinea pig isolated vas deferens during nerve stimulation: evidence for a soluble ecto-nucleoside triphosphate diphosphohydrolase-like ATPase and a soluble ecto-5'-nuc
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Calcium; Chromatography, High Pressure Liquid; Electric Stimulation; Enzyme Inhibitors; Guinea Pigs; In Vitro Techniques; Kinetics; Magnesium; Male; Nucleotidases; Phosphoric Diester Hydrolases; Phosphoric Monoester Hydrolases; Plant Proteins; Pyrophosphatases; Suramin; Sympathetic Nervous System; Vas Deferens | 2002 |
ATP and UTP at low concentrations strongly inhibit bone formation by osteoblasts: a novel role for the P2Y2 receptor in bone remodeling.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Bone Marrow Cells; Dose-Response Relationship, Drug; Osteoblasts; Osteogenesis; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Stimulation, Chemical; Uridine Triphosphate | 2002 |
Rapid adenosine release in the nucleus tractus solitarii during defence response in rats: real-time measurement in vivo.
Topics: Adenosine; Adenosine Diphosphate; Animals; Biosensing Techniques; Brain Stem; Computer Systems; Electric Stimulation; Enzyme Inhibitors; Escape Reaction; Hypothalamus; Inosine; Microelectrodes; Rats; Rats, Sprague-Dawley; Solitary Nucleus; Time Factors | 2002 |
Light activates binding of membrane proteins to chloroplast RNAs in Chlamydomonas reinhardtii.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Chlamydomonas reinhardtii; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Light; Membrane Proteins; Molecular Weight; Protein Binding; Protoporphyrins; RNA-Binding Proteins; RNA, Chloroplast; Thylakoids; Uridine | 2002 |
A viral RNA that binds ATP and contains a motif similar to an ATP-binding aptamer from SELEX.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Base Sequence; Capsid; Chromatography, Thin Layer; DNA; Dose-Response Relationship, Drug; Kinetics; Microscopy, Electron; Models, Molecular; Molecular Sequence Data; Mutation; Nucleic Acid Conformation; Protein Binding; Protein Structure, Secondary; RNA; RNA, Viral | 2003 |
In vitro effects of thyroid hormones on ectonucleotidase activities in synaptosomes from hippocampus of rats.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Extracellular Space; Hippocampus; Hydrolysis; Male; Presynaptic Terminals; Pyrophosphatases; Rats; Rats, Wistar; Synaptosomes; Thyroid Gland; Thyroid Hormones; Thyroxine; Triiodothyronine | 2002 |
ATP protects, by way of receptor-mediated mechanisms, against hypoxia-induced injury in renal proximal tubules.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Energy Metabolism; Hemolysis; Hypotonic Solutions; Hypoxia; Kidney Tubules, Proximal; Kinetics; L-Lactate Dehydrogenase; Male; Potassium; Quinazolines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Thionucleotides; Triazoles | 2003 |
Regulation of mucin secretion from human bronchial epithelial cells grown in murine hosted xenografts.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Bronchi; Cells, Cultured; Epithelial Cells; Goblet Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Mucins; Nitric Oxide; Nitric Oxide Donors; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Respiratory Mucosa; Second Messenger Systems; Species Specificity; Trachea; Transplantation, Heterologous; Uridine Triphosphate; Vasodilator Agents | 2003 |
Pulmonary preservation studies: effects on endothelial function and pulmonary adenine nucleotides.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Allopurinol; Animals; Capillary Permeability; Cyclic AMP; Dextrans; Endothelium, Vascular; Glucose; Glutathione; Hypertonic Solutions; Insulin; Lung; Lung Transplantation; Male; Organ Preservation Solutions; Organ Size; Raffinose; Rats; Rats, Sprague-Dawley; Water | 2003 |
Nucleoside and nucleotide stimulation of fluid secretion in the pigmented rabbit conjunctiva.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Body Fluids; Conjunctiva; In Vitro Techniques; Male; Nucleotides; Rabbits; Uridine Triphosphate | 2002 |
Extracellular purines from cells of seminiferous tubules.
Topics: 5'-Nucleotidase; Adenine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Animals; Cells, Cultured; Dipyridamole; Enzyme Inhibitors; Extracellular Space; Germ Cells; Kinetics; Male; Paracrine Communication; Phosphodiesterase Inhibitors; Purines; Rats; Rats, Wistar; Receptors, Purinergic; Seminiferous Tubules; Sertoli Cells; Thioinosine | 2003 |
Effects of diadenosine polyphosphates and seminal fluid vesicles on rabbit sperm cells.
Topics: 5'-Nucleotidase; Acrosome Reaction; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Dinucleoside Phosphates; Male; Microscopy, Electron; Polyphosphates; Rabbits; Seminal Vesicles; Sperm Capacitation; Spermatozoa; Type C Phospholipases | 2003 |
The human D2 dopamine receptor synergizes with the A2A adenosine receptor to stimulate adenylyl cyclase in PC12 cells.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenine; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenylyl Cyclases; Animals; Benzamides; Binding, Competitive; Cell Cycle; Cell Membrane; Cofilin 1; Colforsin; Cyclic AMP; Cytoskeletal Proteins; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Enzyme Activation; Gene Expression; Glutamic Acid; Humans; Membrane Potentials; Patch-Clamp Techniques; PC12 Cells; Pertussis Toxin; Phenethylamines; Phosphodiesterase Inhibitors; Phosphoproteins; Propionates; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrrolidines; Quinpirole; Radioligand Assay; Rats; Receptors, Dopamine D2; Receptors, Purinergic P1; Thionucleotides; Transfection; Triazines; Triazoles; Xenopus Proteins | 2003 |
Adenosine-mediated early preconditioning in mouse: protective signaling and concentration dependent effects.
Topics: Adenosine; Adenosine Diphosphate; Alkaloids; Animals; Benzophenanthridines; Calcium Channel Blockers; Decanoic Acids; Diazoxide; Enzyme Inhibitors; Hydroxy Acids; Hypoxanthine; Inosine; Ischemic Preconditioning, Myocardial; L-Lactate Dehydrogenase; Male; Mice; Mice, Inbred C57BL; Mitochondria, Heart; Myocardial Contraction; Myocardial Infarction; Necrosis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Perfusion; Phenanthridines; Phenethylamines; Potassium Channels; Protein Kinase C; Receptors, Purinergic P2; Signal Transduction; Xanthine | 2003 |
A novel technique of hypothermic luminal perfusion for small bowel preservation.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Allopurinol; Animals; Energy Metabolism; Glutathione; Insulin; Intestine, Small; Male; Malondialdehyde; Organ Preservation; Organ Preservation Solutions; Perfusion; Raffinose; Rats; Rats, Sprague-Dawley; Transplantation, Homologous | 2003 |
Adenine, an inhibitor of platelet aggregation, from the leaves of Cassia alata.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Cassia; Collagen; Humans; In Vitro Techniques; Light; Plant Leaves; Platelet Aggregation; Platelet Aggregation Inhibitors; Scattering, Radiation; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet | 2003 |
Distinct receptors and different transduction mechanisms for ATP and adenosine at the frog motor nerve endings.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Anura; Dose-Response Relationship, Drug; Drug Interactions; Electrophysiology; Enzyme Inhibitors; In Vitro Techniques; Nerve Endings; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Second Messenger Systems; Synaptic Transmission; Time Factors; Vasodilator Agents | 2003 |
Electrophysiologic effects of adenosine triphosphate on rabbit sinoatrial node pacemaker cells via P1 receptors.
Topics: Action Potentials; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Aminophylline; Animals; Drug Interactions; Male; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rabbits; Sinoatrial Node; Triazines | 2003 |
The analysis of adenosine triphosphate and adenosine diphosphate preparations by paper ionophoresis.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Diphosphates; Ion Exchange; Nucleotides | 1954 |
[Isolation of free nucleotides from various tissues. II. Isolation of adenosine-5-monophosphate, adenosinediphosphate, adenosinetriphosphate, guanosine, cytidine and uridine from ascites tumor of the mouse].
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Ascites; Cytidine; Guanosine; Mice; Neoplasms, Experimental; Nucleotides; Pyrimidines; Uridine | 1954 |
[Correlation between the swelling of isolated mitochondria and decomposition of intramitochondrial adenosine nucleotides (ATP, ADP, AMP, CoA)].
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Liver; Mitochondria; Nucleotides | 1954 |
Rephosphorylation produced by inosine and adenosine of adenosine monophosphate and adenosine diphosphate in human erythrocytes.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Erythrocytes; Humans; Inosine; Nucleotides | 1957 |
[Syntheses in the field of vitamin B 12. XI. On the synthesis of DL-cobinamide phosphoric acid amide, P1-DL-cobinamide-P2-guanosine-5'pyrophosphate and P1-DL-cobinamide-P2-adenosine-5'-pyrophosphate].
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Amides; Cobamides; Diphosphates; Guanosine; Guanosine Diphosphate; Nucleosides; Nucleotides; Phosphates; Phosphoric Acids; Vitamin B 12 | 1962 |
[Enzymatic determination of serum adenosine-5-diphosphoric acid (ADP) and adenosine-5-monophosphoric acid (AMP) in pregnancy and during labor].
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Diphosphates; Erythrocytes; Female; Humans; Labor, Obstetric; Pregnancy; Work | 1963 |
Effect of magnesium and calcium ions on the fluorescence of the protonated ring of adenine, adenosine, adenosine 5'-phosphate, adenosine diphosphate, and adenosine triphosphate.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Calcium; Fluorescence; Ions; Magnesium; Nucleosides | 1963 |
[The oxidation of adenosine derivatives to N1-oxides and the incorporation of ADP-N1-oxide in poly-A by crude bacterial extracts].
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Azotobacter; Nitrogen; Oxidation-Reduction; Oxides; Phthalic Acids; Poly A | 1963 |
PREVENTION BY ADENOSINE OF THE EFFECT OF ADENOSINE DIPHOSPHATE ON THE CONCENTRATION OF CIRCULATING PLATELETS.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Animals; Biomedical Research; Blood Platelets; Infusions, Parenteral; Injections; Injections, Intravenous; Nucleosides; Pharmacology; Rabbits; Research | 1963 |
[AGGREGATION OF PLATELETS WITH ADP (ADENOSINE DIPHOSPHORIC ACID)].
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Blood Platelet Disorders; Blood Platelets; Collagen; Diphosphates; Epinephrine; Hemophilia A; Humans; Leukemia; Leukemia, Myeloid; Norepinephrine; Research; Serotonin | 1964 |
[Differentiation and determination, in tissue and biological fluids, of adenosine tri- and diphosphates (ATP and ADP) by a pharmacological method].
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Body Fluids; Cell Differentiation; Diphosphates | 1959 |
Extracellular ATP and adenosine induce cell apoptosis of human hepatoma Li-7A cells via the A3 adenosine receptor.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Apoptosis; Biological Transport; Carcinoma, Hepatocellular; Caspase 3; Caspases; Cell Division; Cell Line; Cell Line, Tumor; Coformycin; Dipyridamole; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Humans; In Situ Nick-End Labeling; Nucleosides; Oligonucleotide Array Sequence Analysis; Receptor, Adenosine A3; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Reverse Transcriptase Polymerase Chain Reaction; Time Factors; Uridine Triphosphate | 2003 |
Extracellular nucleotides and nucleosides induce proliferation and increase nucleoside transport in human glioma cell lines.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Brain Neoplasms; Cell Division; DNA; Extracellular Space; Glioma; Humans; Nucleosides; Nucleotides; Purinergic P1 Receptor Agonists; Purinergic P2 Receptor Agonists; Purines; Pyrimidines; Receptors, Purinergic P1; Receptors, Purinergic P2; Signal Transduction; Thymidine; Tumor Cells, Cultured; Uridine Diphosphate; Uridine Triphosphate | 2003 |
Activation of P2X7 purinoceptor-stimulated TGF-beta 1 mRNA expression involves PKC/MAPK signalling pathway in a rat brain-derived type-2 astrocyte cell line, RBA-2.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Astrocytes; Blotting, Northern; Blotting, Western; Brain; Carbazoles; Cell Line; Dose-Response Relationship, Drug; Flavonoids; Gene Expression; Indoles; Kinetics; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X4; Receptors, Purinergic P2X7; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2003 |
Cilostazol, an inhibitor of type 3 phosphodiesterase, stimulates large-conductance, calcium-activated potassium channels in pituitary GH3 cells and pheochromocytoma PC12 cells.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Action Potentials; Adenoma; Adenosine; Adenosine Diphosphate; Animals; Calcium Channels, L-Type; Cilostazol; Cyclic Nucleotide Phosphodiesterases, Type 3; Electric Conductivity; Enzyme Inhibitors; Kinetics; Large-Conductance Calcium-Activated Potassium Channels; PC12 Cells; Phosphodiesterase Inhibitors; Pituitary Gland, Anterior; Pituitary Neoplasms; Potassium Channels, Calcium-Activated; Rats; Tetrazoles | 2004 |
Spectrophotometric determination of fructose-1:6-diphosphate, hexosemonophosphates, adenosinetriphosphate and adenosinediphosphate.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Diphosphates; Fructose; Phosphates; Spectrophotometry | 1951 |
Beneficial effects of CD39/ecto-nucleoside triphosphate diphosphohydrolase-1 in murine intestinal ischemia-reperfusion injury.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Blood Platelets; Capillaries; Cyclic AMP; Cytokines; Endothelium, Vascular; Gene Deletion; Intestine, Small; Ischemia; Male; Mice; Mice, Inbred C57BL; Microscopy, Video; Oxidative Stress; Permeability; Peroxidase; Platelet Activation; Reperfusion Injury; Time Factors; Vascular Endothelial Growth Factor A | 2004 |
Triatoma infestans apyrases belong to the 5'-nucleotidase family.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Amino Acid Sequence; Animals; Apyrase; Biological Evolution; Blood Platelets; Blotting, Southern; Blotting, Western; Cell Line; Chromatography; Chromatography, Gel; Cloning, Molecular; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Gene Library; Glycosylation; Humans; Insecta; Mass Spectrometry; Molecular Sequence Data; Peptides; Platelet Aggregation; Polymerase Chain Reaction; Recombinant Proteins; Saliva; Sequence Homology, Amino Acid; Triatoma; Trypanosoma cruzi | 2004 |
Metabolism of P2 receptor agonists in human airways: implications for mucociliary clearance and cystic fibrosis.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Bronchi; Cells, Cultured; Chromatography, High Pressure Liquid; Cilia; Cystic Fibrosis; Epithelial Cells; Humans; Inflammation; Lung; Mucous Membrane; Nucleotides; Purinergic P2 Receptor Agonists; Ribonucleases; RNA, Messenger; Time Factors; Up-Regulation | 2004 |
Role of phosphate chain mobility of MgATP in completing the 3-phosphoglycerate kinase catalytic site: binding, kinetic, and crystallographic studies with ATP and MgATP.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Anions; Binding Sites; Calorimetry; Calorimetry, Differential Scanning; Catalytic Domain; Crystallography, X-Ray; Kinetics; Magnesium; Phosphates; Phosphoglycerate Kinase; Protein Folding; Substrate Specificity; Sulfhydryl Compounds; Swine; Titrimetry | 2004 |
Endothelium-dependent relaxation of canine pulmonary artery after prolonged lung graft preservation in University of Wisconsin solution: role of L-arginine supplementation.
Topics: Acetylcholine; Adenosine; Adenosine Diphosphate; Allopurinol; Animals; Arginine; Dogs; Endothelium, Vascular; Female; Glutathione; Insulin; Lung; Lung Transplantation; Male; Molsidomine; omega-N-Methylarginine; Organ Preservation Solutions; Pulmonary Artery; Raffinose; Sodium Fluoride; Tissue Preservation | 2004 |
Hypoxia induces adenosine release from the rat carotid body.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Carotid Body; Carrier Proteins; Chemoreceptor Cells; Dipyridamole; Enzyme Inhibitors; Hypoxia; In Vitro Techniques; Membrane Transport Proteins; Nucleoside Transport Proteins; Rats; Rats, Wistar; Thioinosine | 2004 |
Evaluation of the viability and energy metabolism of canine pancreas graft subjected to significant warm ischemia damage during preservation by UW solution cold storage method.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Allopurinol; Animals; Cold Temperature; Dogs; Energy Metabolism; Female; Glutathione; Graft Survival; Hot Temperature; Insulin; Ischemia; Islets of Langerhans; Male; Organ Preservation Solutions; Pancreas; Pancreas Transplantation; Raffinose | 2004 |
Nucleotide release provides a mechanism for airway surface liquid homeostasis.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Cell Line; Cells, Cultured; Chromatography, High Pressure Liquid; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; Firefly Luciferin; Humans; Hydrolysis; Luciferases; Microscopy, Confocal; Mucous Membrane; Nucleotides; Protein Kinase C; Purines; Receptor, Adenosine A2B; Respiratory Mucosa; Respiratory System; Time Factors; Trachea | 2004 |
Brain to blood efflux transport of adenosine: blood-brain barrier studies in the rat.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Kinase; Adenosine Triphosphate; Animals; Biological Transport; Blood Flow Velocity; Blood-Brain Barrier; Brain; Brain Chemistry; Carbon Radioisotopes; Cerebrovascular Circulation; Drug Administration Routes; Enzyme Inhibitors; Female; GABA Modulators; Kinetics; Leucine; Male; Models, Biological; Rats; Rats, Wistar; Sucrose; Thiopental | 2004 |
Characterization of purine receptors in mouse thoracic aorta.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Aorta, Thoracic; Biological Factors; Calcimycin; Dose-Response Relationship, Drug; Endothelium, Vascular; Male; Mice; Mice, Inbred ICR; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroglycerin; Phenylephrine; Receptors, Purinergic P2; Uridine Triphosphate | 2004 |
Clopidogrel (Plavix) and cardiac surgical patients: implications for platelet function monitoring and postoperative bleeding.
Topics: Adenosine; Adenosine Diphosphate; Aged; Aged, 80 and over; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Function Tests; Postoperative Hemorrhage; Purinergic P2 Receptor Antagonists; Retrospective Studies; Thrombelastography; Ticlopidine; Time Factors | 2004 |
Mechanical ventilation alters airway nucleotides and purinoceptors in lung and extrapulmonary organs.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Bronchoalveolar Lavage; Fas Ligand Protein; Kidney; Liver; Lung; Male; Membrane Glycoproteins; Nucleotides; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Respiration, Artificial; Respiratory System | 2005 |
[The contraction of actomyosin in the presence of adenosine-diphosphate (ADP)].
Topics: Actomyosin; Adenosine; Adenosine Diphosphate; Biochemical Phenomena; Biochemistry; Humans; Myosins | 1950 |
Biochemical brain markers and purinergic parameters in rat CSF after seizure induced by pentylenetetrazol.
Topics: Adenosine; Adenosine Diphosphate; Animals; Antigens, CD; Apyrase; Biomarkers; Brain; Convulsants; Disease Models, Animal; Female; Guanosine; Guanosine Diphosphate; Hydrolysis; Inosine; Nerve Degeneration; Nerve Growth Factors; Nerve Tissue Proteins; Pentylenetetrazole; Phosphopyruvate Hydratase; Purines; Rats; Rats, Wistar; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Seizures; Time Factors; Up-Regulation | 2004 |
Direct excitation of inhibitory interneurons by extracellular ATP mediated by P2Y1 receptors in the hippocampal slice.
Topics: Action Potentials; Adenosine; Adenosine A1 Receptor Agonists; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Astrocytes; Extracellular Fluid; Female; Hippocampus; In Vitro Techniques; Interneurons; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurotransmitter Agents; Organ Specificity; Patch-Clamp Techniques; Purinergic P2 Receptor Agonists; Pyramidal Cells; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptors, Presynaptic; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Species Specificity; Thionucleotides | 2004 |
Regulation of VEGF and bFGF mRNA expression and other proliferative compounds in skeletal muscle cells.
Topics: Adenosine; Adenosine Diphosphate; Animals; Cell Proliferation; Cells, Cultured; Electric Stimulation; Endothelium, Vascular; Fibroblast Growth Factor 2; Gene Expression Regulation; Humans; Indomethacin; Male; Muscle Cells; Muscle Contraction; Muscle, Skeletal; Nitric Oxide; Nitroarginine; Penicillamine; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; RNA, Messenger; Vascular Endothelial Growth Factor A | 2004 |
The influence of short-term fasting on the quality of small bowel graft preservation.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Allopurinol; Ammonia; Animals; Carbohydrate Metabolism; Cold Temperature; Cryopreservation; Fasting; Food Deprivation; Glutathione; Insulin; Intestinal Mucosa; Intestine, Small; Lactates; Male; Malondialdehyde; Organ Preservation; Organ Preservation Solutions; Oxidative Stress; Raffinose; Rats; Rats, Sprague-Dawley; Temperature; Time Factors; Transplantation | 2005 |
Asphyxia and depolarization increase adenosine levels in perilymph.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Analysis of Variance; Animals; Asphyxia; Female; Guinea Pigs; Male; Neurotransmitter Agents; Perilymph; Potassium | 2005 |
Compensation of endothelium-dependent responses in coronary circulation of eNOS-deficient mice.
Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Adaptation, Physiological; Adenosine; Adenosine Diphosphate; Age Factors; Animals; Aorta; Bradykinin; Coronary Circulation; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Genotype; Heart; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Nitric Oxide Synthase Type III; Vasodilation; Vasodilator Agents | 2005 |
Adenosine stimulates anabolic metabolism in developing castor bean (Ricinus communis L.) cotyledons.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Carbon Dioxide; Cotyledon; Energy Metabolism; Enzyme Activation; Glucosephosphate Dehydrogenase; Nucleic Acids; Oxygen; Ricinus communis; Seedlings; Starch; Transferases | 2006 |
Amitriptyline enhances extracellular tissue levels of adenosine in the rat hindpaw and inhibits adenosine uptake.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Biological Transport; Capsaicin; Cell Line, Tumor; Dose-Response Relationship, Drug; Equilibrative-Nucleoside Transporter 2; Extracellular Space; Hindlimb; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Time Factors | 2005 |
Ecto-hydrolysis of adenine nucleotides in rat blood platelets are altered by ovariectomy.
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Blood Platelets; Cell Membrane; Enzyme Activation; Estrogen Replacement Therapy; Female; Hydrolysis; Ovariectomy; Rats; Rats, Wistar | 2005 |
Vessel tone and remodeling.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Endothelium, Vascular; Humans; Hypoxia; Ion Channels; Models, Biological; Neuropeptide Y; Nitric Oxide; Norepinephrine; Receptors, Purinergic P2; Receptors, Purinergic P2X4; Regional Blood Flow; Signal Transduction; Vasodilation | 2006 |
Postnatal development of P2 receptors in the murine gastrointestinal tract.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Age Factors; Analysis of Variance; Animals; Animals, Newborn; Blotting, Western; Dose-Response Relationship, Drug; Female; Gastrointestinal Tract; Gene Expression Regulation, Developmental; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Muscle, Smooth; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Thionucleotides; Uridine Triphosphate | 2006 |
Extracellular nucleotide signaling in adult neural stem cells: synergism with growth factor-mediated cellular proliferation.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Alkaline Phosphatase; Animals; Calcium; Cell Proliferation; Cells, Cultured; Epidermal Growth Factor; Fibroblast Growth Factor 2; Isoenzymes; Mice; Mice, Inbred C57BL; Mice, Knockout; Multipotent Stem Cells; Neurons; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y2; Signal Transduction; Uridine Triphosphate | 2006 |
Magnesium influences the discrimination and release of ADP by human RAD51.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Biosensing Techniques; Catalytic Domain; DNA; DNA Repair; DNA-Binding Proteins; Humans; Kinetics; Magnesium; Protein Binding; Protein Structure, Tertiary; Rad51 Recombinase; Rec A Recombinases | 2006 |
Ameliorating injury during preservation and isolation of human islets using the two-layer method with perfluorocarbon and UW solution.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Allopurinol; Cell Separation; Cell Survival; Cold Temperature; Cryopreservation; Energy Metabolism; Fluorocarbons; Glutathione; Humans; Insulin; Islets of Langerhans; Islets of Langerhans Transplantation; Lipid Peroxidation; Organ Preservation Solutions; Oxidative Stress; Preservation, Biological; Raffinose; Time Factors | 2006 |
Adenosine phosphonoacetic acid is slowly metabolized by NDP kinase.
Topics: Adenosine; Adenosine Diphosphate; Animals; Binding Sites; Catalysis; Crystallization; Dictyostelium; Enzyme Inhibitors; Humans; Kinetics; Models, Molecular; Molecular Structure; Nucleoside-Diphosphate Kinase; Phosphonoacetic Acid; Structure-Activity Relationship; X-Ray Diffraction | 2005 |
Regulation of death and survival in astrocytes by ADP activating P2Y1 and P2Y12 receptors.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Apoptosis; Apyrase; Astrocytes; Cell Line, Tumor; Cell Survival; Humans; In Situ Nick-End Labeling; Protein Serine-Threonine Kinases; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Thionucleosides; Tumor Necrosis Factor-alpha | 2006 |
Stimulation of adenosine A1 and A2A receptors by AMP in the submucosal plexus of guinea pig small intestine.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Action Potentials; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Boron Compounds; Enzyme Inhibitors; Estrenes; Excitatory Postsynaptic Potentials; Guinea Pigs; Ileum; Indoles; Male; Maleimides; Norepinephrine; Phenethylamines; Pyrrolidinones; Quinazolines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Signal Transduction; Submucous Plexus; Synaptic Transmission; Tetrodotoxin; Theophylline; Triazines; Triazoles | 2007 |
Role of the influenza virus heterotrimeric RNA polymerase complex in the initiation of replication.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Cell Line; Dimerization; DNA-Directed RNA Polymerases; Humans; Nucleic Acid Conformation; Orthomyxoviridae; Promoter Regions, Genetic; Protein Subunits; Recombinant Proteins; Ribonucleoproteins; RNA-Dependent RNA Polymerase; RNA, Complementary; RNA, Viral; Viral Proteins; Virus Replication | 2006 |
Adenosine A1 and A2 receptor agonists reduce endotoxin-induced cellular energy depletion and oedema formation in the lung.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Adenosine Diphosphate; Adenosine Triphosphate; Analysis of Variance; Animals; Blood Pressure; Chromatography, High Pressure Liquid; Disease Models, Animal; Endotoxemia; Endotoxins; Energy Metabolism; Female; Lipopolysaccharides; Lung; Pulmonary Artery; Pulmonary Edema; Rabbits; Receptors, Purinergic P1; Respiratory Distress Syndrome; Time Factors; Uric Acid; Vasoconstriction | 2007 |
A novel mechanism of vasoregulation: ADP-induced relaxation of the porcine isolated coronary artery is mediated via adenosine release.
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Coronary Vessels; Dose-Response Relationship, Drug; Female; Gene Expression; In Vitro Techniques; Male; Molecular Sequence Data; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Pyrimidines; Receptor, Adenosine A2A; Receptors, Purinergic P1; Receptors, Purinergic P2; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Swine; Triazoles; Vasodilation; Vasodilator Agents | 2007 |
The effects of angiotensin II and genetic hypertension upon extracellular nucleotide hydrolysis by rat platelet ectoenzymes.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Angiotensin II; Animals; Blood Platelets; Enzyme Activation; Hydrolysis; Hypertension; Male; Phenotype; Phosphoric Diester Hydrolases; Rats; Rats, Inbred SHR; Rats, Wistar; Receptor, Angiotensin, Type 1; Thymidine Monophosphate; Vasoconstrictor Agents | 2007 |
AMP does not induce torpor.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aminophylline; Animals; Blood Pressure; Body Temperature; Dose-Response Relationship, Drug; Electrocardiography; Female; Heart Rate; Hibernation; Mice; Mice, Inbred C57BL; Purinergic P1 Receptor Antagonists; Telemetry | 2007 |
A1 adenosine receptor upregulation accompanies decreasing myocardial adenosine levels in mice with left ventricular dysfunction.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Disease Models, Animal; Female; Heart Failure; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Transgenic; Myocardium; Receptor, Adenosine A1; Receptor, Adenosine A2A; Signal Transduction; Tumor Necrosis Factor-alpha; Up-Regulation; Ventricular Dysfunction, Left | 2007 |
Purinergic receptor activation inhibits mitogen-stimulated proliferation in primary neurospheres from the adult mouse subventricular zone.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cell Proliferation; Colforsin; Cyclic AMP; Mice; Mice, Inbred CBA; Neurons; Nucleotides; Protein Isoforms; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P1; Receptors, Purinergic P2; Thionucleotides; Tissue Culture Techniques | 2007 |
Nitrergic and purinergic interplay in inhibitory transmission in rat gastric fundus.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Apamin; Electric Stimulation; Enzyme Inhibitors; Female; Gastric Fundus; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Nitrergic Neurons; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Rats; Rats, Wistar; Receptors, Purinergic; Tetrodotoxin | 2007 |
Relative importance of mechanisms needs clarification.
Topics: Adenosine; Adenosine Diphosphate; Animals; Models, Cardiovascular; Muscle Relaxation; Myocardial Contraction; Receptor, Adenosine A2A; Receptors, Purinergic P2; Swine; Thionucleotides | 2007 |
Molecule of the month. Ticagrelor.
Topics: Adenosine; Adenosine Diphosphate; Cardiovascular Diseases; Humans; Platelet Activation; Platelet Aggregation Inhibitors; Ticagrelor | 2007 |
Ecto-5'-nucleotidase promotes invasion, migration and adhesion of human breast cancer cells.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Breast Neoplasms; Cell Adhesion; Cell Movement; Extracellular Matrix; Female; Humans; Neoplasm Invasiveness; Transfection | 2008 |
Lack of effect of extracellular adenosine generation and signaling on renal erythropoietin secretion during hypoxia.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Arteries; Carbon Monoxide; Erythropoietin; Extracellular Fluid; Hemodilution; Hypoxia; Kidney; Mice; Mice, Inbred C57BL; Mice, Knockout; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; RNA, Messenger; Signal Transduction | 2007 |
Adenosine uptake-dependent C6 cell growth inhibition.
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Kinase; Adenosine Monophosphate; Animals; Brain Neoplasms; Cell Count; Cell Line, Tumor; Cell Proliferation; Cyclic AMP; Dipyridamole; Equilibrative Nucleoside Transporter 1; Equilibrative-Nucleoside Transporter 2; Glioma; Hydrolysis; Rats; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Thioinosine; Uridine | 2007 |
hMSH4-hMSH5 adenosine nucleotide processing and interactions with homologous recombination machinery.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Cell Cycle Proteins; DNA, Cruciform; Humans; Meiosis; Models, Biological; Models, Genetic; Protein Binding; Recombination, Genetic | 2008 |
Role of extracellular nucleotide phosphohydrolysis in intestinal ischemia-reperfusion injury.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Base Sequence; Caco-2 Cells; Cell Line; DNA Primers; Enzyme Inhibitors; Extracellular Fluid; Female; Humans; Hydrolysis; Interleukin-1beta; Interleukin-6; Intestinal Mucosa; Intestines; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Purinergic P1; Reperfusion Injury; Signal Transduction | 2008 |
Effect of purines on calcium-independent acetylcholine release at the mouse neuromuscular junction.
Topics: Acetylcholine; Adenosine; Adenosine A1 Receptor Agonists; Adenosine Diphosphate; Animals; Calcium; Electrophysiology; Exocytosis; Mice; Neuromuscular Junction; Purinergic P2 Receptor Agonists; Purines; Synaptic Transmission; Thionucleotides | 2008 |
P2Y1 receptor signaling enhances neuroprotection by astrocytes against oxidative stress via IL-6 release in hippocampal cultures.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Animals, Newborn; Astrocytes; Cell Survival; Cells, Cultured; Coculture Techniques; Dose-Response Relationship, Drug; Drug Interactions; Enzyme-Linked Immunosorbent Assay; Hippocampus; Hydrogen Peroxide; Interleukin-6; Neurons; Oxidants; Oxidative Stress; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Thionucleosides | 2009 |
Erythrocytic adenosine monophosphate as an alternative purine source in Plasmodium falciparum.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Cytoplasm; Erythrocytes; Humans; Models, Biological; Models, Chemical; Nucleosides; Oocytes; Plasmodium falciparum; Polymerase Chain Reaction; Purines; Xenopus laevis | 2008 |
Ischemia-driven expression of CD73 confers tissue protection during liver ischemia/reperfusion.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Disease Models, Animal; Extracellular Fluid; Liver; Mice; Mice, Knockout; Reperfusion Injury | 2008 |
Coenzyme binding and hydride transfer in Rhodobacter capsulatus ferredoxin/flavodoxin NADP(H) oxidoreductase.
Topics: Adenosine; Adenosine Diphosphate; Bacterial Proteins; Catalytic Domain; Crystallography, X-Ray; Ferredoxin-NADP Reductase; Ferredoxins; Flavodoxin; Kinetics; Models, Molecular; NADP; Protein Binding; Protein Conformation; Recombinant Proteins; Rhodobacter capsulatus | 2009 |
Effect of blocking platelet activation with AZD6140 on development of abdominal aortic aneurysm in a rat aneurysmal model.
Topics: Adenosine; Adenosine Diphosphate; Animals; Aorta; Aortic Aneurysm, Abdominal; Blood Platelets; Disease Models, Animal; Disease Progression; Elastic Tissue; Guinea Pigs; Inflammation; Male; Matrix Metalloproteinase 9; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Rats; Rats, Inbred Lew; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Thrombosis; Ticagrelor; Time Factors; Transplantation, Heterologous | 2009 |
Evidence of a new phosphoryl transfer system in nucleotide metabolism.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenylate Kinase; Animals; Genetic Diseases, Inborn; Hematologic Diseases; Kinetics; Liver; Models, Biological; Nucleotides; Phosphorylation; Phosphotransferases; Rats; Substrate Specificity | 2009 |
The reversible oral P2Y12 antagonist AZD6140 inhibits ADP-induced contractions in murine and human vasculature.
Topics: Adenosine; Adenosine Diphosphate; Administration, Oral; Aged; Animals; Aorta, Thoracic; Female; Humans; Male; Mammary Arteries; Mice; Receptors, Purinergic P2Y12; Species Specificity; Ticagrelor; Vasoconstriction; Vasoconstrictor Agents | 2010 |
Adenosine inhibition of adenosine diphosphate and thrombin-induced monocyte-platelet aggregates in cardiac syndrome X.
Topics: Adenosine; Adenosine Diphosphate; Antigens, CD; Biomarkers; Blood Platelets; Case-Control Studies; Female; Humans; Male; Microvascular Angina; Middle Aged; Monocytes; P-Selectin; Platelet Aggregation; Thrombin; Thromboplastin; Time Factors | 2009 |
Nucleotide-responsive wettability on a smart polymer surface.
Topics: Acrylamides; Acrylic Resins; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Boronic Acids; Hydrophobic and Hydrophilic Interactions; Microscopy, Atomic Force; Nucleotides; Phenylthiourea; Polymers; Silicon; Solutions; Surface Properties; Wettability | 2009 |
Time-course changes in ectonucleotidase activities during experimental autoimmune encephalomyelitis.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Apyrase; Cell Membrane; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Multiple Sclerosis; Rats; Rats, Inbred Strains; Spinal Cord; Time Factors | 2009 |
Ticagrelor binds to human P2Y(12) independently from ADP but antagonizes ADP-induced receptor signaling and platelet aggregation.
Topics: Adenosine; Adenosine Diphosphate; Animals; Binding Sites; Blood Platelets; Cell Membrane; CHO Cells; Cricetinae; Cricetulus; Humans; Kinetics; Platelet Aggregation; Protein Binding; Pyrimidines; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Signal Transduction; Ticagrelor | 2009 |
Effect of oxygenated perfluorocarbon on isolated islets during transportation.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Allopurinol; Animals; Cell Culture Techniques; Cell Separation; Culture Media; Fluorocarbons; Glutathione; Humans; Insulin; Islets of Langerhans; Islets of Langerhans Transplantation; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Organ Culture Techniques; Organ Preservation Solutions; Raffinose; Rats; Rats, Inbred Lew; Tissue Donors; Transportation | 2010 |
[Pharmacological characteristics of contractile responses regulated by P2Y receptors in circular smooth muscle of the rat gastric body].
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Gastric Fundus; Male; Muscle Contraction; Muscle, Smooth; Purinergic P2 Receptor Agonists; Rats; Rats, Wistar; Receptors, Purinergic P2; Stomach; Thionucleotides; Uridine Triphosphate | 2009 |
Extracellular ADP regulates lesion-induced in vivo cell proliferation and death in the zebrafish retina.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Age Factors; Animals; Antimetabolites; Bromodeoxyuridine; Cell Death; Cell Differentiation; Cell Division; Cell Membrane; Enzyme Inhibitors; Extracellular Space; Hydrolysis; Ouabain; Paracrine Communication; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Retina; Zebrafish | 2009 |
Studies of the extracellular ATP-adenosine pathway in human urinary tract epithelial cells.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Biosynthetic Pathways; Cell Line; Epithelial Cells; Humans; Neutrophils; Nucleotidases; Urinary Tract | 2009 |
Role of oxidative stress and adenosine nucleotides in the liver of aging rats.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Age Factors; Aging; Animals; Catalase; Dinoprostone; Lipid Peroxidation; Liver; Male; Mitochondria, Liver; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase; Superoxides; Thiobarbituric Acid Reactive Substances | 2010 |
Tripartite purinergic modulation of central respiratory networks during perinatal development: the influence of ATP, ectonucleotidases, and ATP metabolites.
Topics: 5'-Nucleotidase; Action Potentials; Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Animals, Newborn; Excitatory Postsynaptic Potentials; Neural Inhibition; Organ Culture Techniques; Periodicity; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptors, Purinergic P2; Respiration; Respiratory Center; Rhombencephalon | 2009 |
Adenosine A1 receptors and microglial cells mediate CX3CL1-induced protection of hippocampal neurons against Glu-induced death.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine Deaminase; Adenosine Diphosphate; Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Cell Death; Cell Movement; Clodronic Acid; CX3C Chemokine Receptor 1; Erythropoietin; Glutamic Acid; Green Fluorescent Proteins; Hippocampus; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Neurons; Organ Culture Techniques; Rats; Receptor, Adenosine A1; Receptors, Adenosine A2; Receptors, Chemokine; Xanthines | 2010 |
Changes in platelets and anticoagulant protein activity during adenosine-exercise single-photon emission computed tomography stress test.
Topics: Adenosine; Adenosine Diphosphate; Adult; Aged; Antithrombins; Aspirin; beta-Thromboglobulin; Blood Coagulation; Clopidogrel; Coronary Stenosis; Epinephrine; Exercise Test; Female; Humans; Male; Middle Aged; Myocardial Perfusion Imaging; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Factor 4; Protein C; Ticlopidine; Tomography, Emission-Computed, Single-Photon; Vasodilator Agents | 2010 |
Normothermic versus hypothermic ex vivo flush using a novel phosphate-free preservation solution (AQIX) in porcine kidneys.
Topics: Acid-Base Equilibrium; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Allopurinol; Animals; Citrates; Glutathione; Hypothermia, Induced; Insulin; Kidney; Kidney Transplantation; Microcirculation; Organ Preservation Solutions; Phosphates; Raffinose; Reperfusion Injury; Spouses; Temperature | 2011 |
Effect of purinergic receptor activation on Na+-K+ pump activity, excitability, and function in depolarized skeletal muscle.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Deoxyadenine Nucleotides; Estrenes; Excitation Contraction Coupling; Membrane Potentials; Muscle Contraction; Muscle Strength; Muscle, Skeletal; Phosphodiesterase Inhibitors; Potassium; Purinergic Antagonists; Purines; Pyrrolidinones; Rats; Receptors, Purinergic; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Sodium-Potassium-Exchanging ATPase; Thiadiazoles; Time Factors; Type C Phospholipases; Uridine Triphosphate | 2010 |
Metabolic regulation of coronary vascular tone: role of hydrogen peroxide, purinergic components, and angiotensin.
Topics: Adenosine; Adenosine Diphosphate; Angiotensin Receptor Antagonists; Angiotensins; Animals; Arterioles; Catalase; Coronary Vessels; Hydrogen Peroxide; Imidazoles; In Vitro Techniques; Lactic Acid; Male; Myocytes, Cardiac; Oxygen; Purinergic P1 Receptor Antagonists; Purinergic P2Y Receptor Antagonists; Rats; Rats, Wistar; Superoxides; Tetrazoles; Theophylline; Vascular Resistance; Vasoconstriction; Vasodilation | 2010 |
Adenosine derived from ADP can contribute to inhibition of platelet aggregation in the presence of a P2Y12 antagonist.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Blood Platelets; Cell Adhesion Molecules; Erythrocytes; Humans; Microfilament Proteins; Phosphoproteins; Phosphorylation; Piperazines; Platelet Aggregation; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Receptors, Thrombin; Thiophenes; Ticagrelor | 2011 |
Extracellular Ca(2+) modulates ADP-evoked aggregation through altered agonist degradation: implications for conditions used to study P2Y receptor activation.
Topics: Adenosine; Adenosine Diphosphate; Blood Platelets; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Humans; Platelet Aggregation; Receptors, Purinergic P2Y12; Thromboxane A2 | 2011 |
CD73 has distinct roles in nonhematopoietic and hematopoietic cells to promote tumor growth in mice.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Chemotaxis, Leukocyte; Disease Progression; Female; Immunotherapy, Adoptive; Lymphocytes, Tumor-Infiltrating; Lymphoma, Non-Hodgkin; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Molecular Targeted Therapy; Ovarian Neoplasms; Peritoneal Neoplasms; Radiation Chimera; Second Messenger Systems; T-Lymphocytes; T-Lymphocytes, Regulatory; Tumor Burden | 2011 |
A homogeneous and nonisotopic assay for phosphatidylinositol 4-kinases.
Topics: 1-Phosphatidylinositol 4-Kinase; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Androstadienes; Animals; Cattle; Cell Line; Chromatography, Affinity; Dimethyl Sulfoxide; Enzyme Assays; High-Throughput Screening Assays; Humans; Isotope Labeling; Kinetics; Protein Kinase Inhibitors; Radiometry; Wortmannin | 2011 |
Role of the ecto-nucleotidases in the cooperative effect of adenosine and neuropeptide-S on locomotor activity in mice.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Enzyme Inhibitors; Injections, Intraventricular; Male; Mice; Motor Activity; Neostriatum; Neuropeptides | 2011 |
Chronic hypoxia impairs extracellular nucleotide metabolism and barrier function in pulmonary artery vasa vasorum endothelial cells.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Analysis of Variance; Animals; Animals, Newborn; Antigens, CD; Apyrase; Blotting, Western; Capillary Permeability; Cattle; Cell Proliferation; Cyclic AMP; Dextrans; DNA Primers; Endothelial Cells; Fluorescein-5-isothiocyanate; Hypoxia; Neovascularization, Pathologic; Pulmonary Artery; Regression Analysis; Reverse Transcriptase Polymerase Chain Reaction; Vasa Vasorum | 2011 |
Cultured astrocytes do not release adenosine during hypoxic conditions.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Animals, Newborn; Astrocytes; Cell Culture Techniques; Cell Hypoxia; Cell Line, Tumor; Cells, Cultured; Chromatography, High Pressure Liquid; Luminescent Measurements; Rats; Rats, Wistar | 2012 |
CD73-generated extracellular adenosine in chronic lymphocytic leukemia creates local conditions counteracting drug-induced cell death.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Antigens, CD; Antineoplastic Agents, Phytogenic; Apyrase; Autocrine Communication; Cell Death; Cell Differentiation; Cell Movement; Cell Survival; Etoposide; Extracellular Space; GPI-Linked Proteins; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Paracrine Communication; Receptor, Adenosine A2A; Tumor Cells, Cultured | 2011 |
Enzymatic properties of Staphylococcus aureus adenosine synthase (AdsA).
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Metals; Nucleotidases; Staphylococcus aureus | 2011 |
Role of newly formed platelets in thrombus formation in rat after clopidogrel treatment: comparison to the reversible binding P2Y₁₂ antagonist ticagrelor.
Topics: Adenosine; Adenosine Diphosphate; Animals; Blood Platelets; Clopidogrel; Cytoprotection; Platelet Activation; Protein Binding; Purinergic P2Y Receptor Antagonists; Rats; Rats, Inbred WKY; Thrombosis; Ticagrelor; Ticlopidine | 2011 |
Impaired ATP-induced coronary blood flow and diminished aortic NTPDase activity precede lesion formation in apolipoprotein E-deficient mice.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Aorta, Thoracic; Apolipoproteins E; Coronary Artery Disease; Coronary Circulation; Female; Hyperemia; Lymphatic System; Male; Mice; Mice, Inbred C57BL; Nucleoside-Triphosphatase; Receptors, Purinergic P2Y; Signal Transduction; Vasodilation; Vasodilator Agents | 2012 |
Alterations in the extracellular catabolism of nucleotides are involved in the antiproliferative effect of quercetin in human bladder cancer T24 cells.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Synergism; Extracellular Space; GPI-Linked Proteins; Humans; Hydrolysis; Nucleotides; Quercetin; Time Factors; Urinary Bladder Neoplasms | 2013 |
Ticagrelor, but not clopidogrel and prasugrel, prevents ADP-induced vascular smooth muscle cell contraction: a placebo-controlled study in rats.
Topics: Adenosine; Adenosine Diphosphate; Animals; Arteries; Clopidogrel; Muscle Contraction; Myocytes, Smooth Muscle; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Rats; Rats, Wistar; Thiophenes; Ticagrelor; Ticlopidine | 2012 |
Opposing effects of ATP and adenosine on barrier function of rat coronary microvasculature.
Topics: Actin Cytoskeleton; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Cadherins; Cells, Cultured; Coronary Vessels; Edema, Cardiac; Endothelial Cells; Male; Myocardium; Permeability; Protein Transport; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline; Venules | 2012 |
Adenosine A3 receptor is involved in ADP-induced microglial process extension and migration.
Topics: Adenosine; Adenosine A3 Receptor Agonists; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Animals; Animals, Newborn; Cell Movement; Cells, Cultured; Cerebral Cortex; Chemotaxis; Collagen; Flow Cytometry; Indicators and Reagents; JNK Mitogen-Activated Protein Kinases; Microglia; Purinergic P2Y Receptor Agonists; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Receptor, Adenosine A1; Receptor, Adenosine A3; Receptors, Purinergic P2Y12; Thionucleotides | 2012 |
Neuronal adenosine release, and not astrocytic ATP release, mediates feedback inhibition of excitatory activity.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Astrocytes; Brain; CA1 Region, Hippocampal; Excitatory Postsynaptic Potentials; Feedback, Physiological; GPI-Linked Proteins; Long-Term Synaptic Depression; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Patch-Clamp Techniques; Receptor, Adenosine A1; Seizures | 2012 |
Nicotine alters the ectonucleotidases activities in lymphocytes: In vitro and in vivo studies.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cotinine; Hydrolysis; Lymphocytes; Male; Nicotine; Nucleotidases; Purines; Rats; Rats, Wistar | 2012 |
Activities of ectonucleotidases and adenosine deaminase in platelets of dogs experimentally infected with Rangelia vitalii.
Topics: Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Babesia; Babesiosis; Blood Coagulation Disorders; Blood Platelets; Brazil; Deamination; Dog Diseases; Dogs; Female; Hemorrhage; Hydrolysis; Nucleotidases; Platelet Count | 2012 |
Synthesis and biological evaluation of ticagrelor derivatives as novel antiplatelet agents.
Topics: Adenosine; Adenosine Diphosphate; Animals; Blood Platelets; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Rats; Receptors, Purinergic P2Y12; Structure-Activity Relationship; Ticagrelor | 2012 |
BF066, a novel dual target antiplatelet agent without significant bleeding.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Arterioles; Chlorides; Collagen; Ferric Compounds; Fibrinogen; Hemorrhage; Humans; Immobilized Proteins; Mice; Mice, Inbred C57BL; Oligopeptides; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptor, Adenosine A2A; Thrombin; Thrombosis | 2012 |
Enzyme-coupled assays for simultaneous detection of nanomolar ATP, ADP, AMP, adenosine, inosine and pyrophosphate concentrations in extracellular fluids.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Cell Line, Tumor; Chromatography, Thin Layer; Diphosphates; Enzyme Assays; Extracellular Fluid; Fluorometry; Homeostasis; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Inosine; Luminescent Measurements; Lymphocytes; Neoplasm Metastasis; Nucleosides; Nucleotides; Pyrophosphatases | 2012 |
Heterosynaptic long-term depression mediated by ATP released from astrocytes.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antigens; Astrocytes; Biophysics; Calcium; Calcium Signaling; Cells, Cultured; Channelrhodopsins; Electric Stimulation; Embryo, Mammalian; Excitatory Postsynaptic Potentials; Genetic Vectors; Glial Fibrillary Acidic Protein; Green Fluorescent Proteins; Hippocampus; In Vitro Techniques; Long-Term Synaptic Depression; Mice; Mice, Inbred C57BL; Neurons; Optical Phenomena; Patch-Clamp Techniques; Proteoglycans; Purinergic P1 Receptor Antagonists; Purinergic P2Y Receptor Antagonists; Rats; Serine; Theophylline; Time Factors; Transfection | 2013 |
Extracellular 2',3'-cAMP-adenosine pathway in proximal tubular, thick ascending limb, and collecting duct epithelial cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Epithelial Cells; Kidney Tubules, Collecting; Kidney Tubules, Proximal; Loop of Henle; Male; Rats; Rats, Sprague-Dawley; Xanthines | 2013 |
Crystal structure of the human ecto-5'-nucleotidase (CD73): insights into the regulation of purinergic signaling.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Amino Acid Sequence; Catalytic Domain; Coordination Complexes; Crystallography, X-Ray; Enzyme Inhibitors; Flavonoids; GPI-Linked Proteins; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Molecular Sequence Data; Protein Binding; Protein Interaction Domains and Motifs; Protein Structure, Quaternary; Protein Structure, Secondary; Protein Subunits; Signal Transduction; Structural Homology, Protein; Zinc | 2012 |
The P2Y(12) antagonists, 2MeSAMP and cangrelor, inhibit platelet activation through P2Y(12)/G(i)-dependent mechanism.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Blood Platelets; Cell Adhesion Molecules; Colforsin; Cyclic AMP; Epoprostenol; Mice; Mice, Knockout; Microfilament Proteins; Phosphoproteins; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Proto-Oncogene Proteins c-akt; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y; Signal Transduction; Thionucleosides | 2012 |
Evaluation of the pharmacokinetics and pharmacodynamics of ticagrelor co-administered with aspirin in healthy volunteers.
Topics: Adenosine; Adenosine Diphosphate; Adult; Aspirin; Bleeding Time; Clopidogrel; Collagen; Drug Therapy, Combination; Female; Healthy Volunteers; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticagrelor; Ticlopidine; Young Adult | 2013 |
Why myotoxin-containing snake venoms possess powerful nucleotidases?
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Crotalid Venoms; Group II Phospholipases A2; Mice; Mice, Inbred C57BL; Nucleotidases; Reptilian Proteins | 2013 |
Investigation of NADH binding, hydride transfer, and NAD(+) dissociation during NADH oxidation by mitochondrial complex I using modified nicotinamide nucleotides.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Diphosphate Ribose; Adenosine Monophosphate; Animals; Binding, Competitive; Cattle; Coenzymes; Electron Transport Complex I; Flavins; Hydrogen; Kinetics; Mitochondria, Heart; Models, Molecular; NAD; Nicotinamide Mononucleotide; Oxidation-Reduction; Protein Binding | 2013 |
High-dose, but not low-dose, aspirin impairs anticontractile effect of ticagrelor following ADP stimulation in rat tail artery smooth muscle cells.
Topics: Adenosine; Adenosine Diphosphate; Animals; Arteries; Aspirin; Dose-Response Relationship, Drug; Endothelium, Vascular; Male; Muscle Contraction; Myocytes, Smooth Muscle; Rats; Tail; Ticagrelor; Vasoconstriction | 2013 |
Comparison of antiplatelet effects of prasugrel and ticagrelor in cynomolgus monkeys by an ELISA-based VASP phosphorylation assay and platelet aggregation.
Topics: Adenosine; Adenosine Diphosphate; Administration, Oral; Adult; Animals; Cell Adhesion Molecules; Clinical Protocols; Enzyme-Linked Immunosorbent Assay; Humans; Macaca fascicularis; Male; Microfilament Proteins; Phosphoproteins; Phosphorylation; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Thiophenes; Ticagrelor; Young Adult | 2013 |
Isolated noncatalytic and catalytic subunits of F1-ATPase exhibit similar, albeit not identical, energetic strategies for recognizing adenosine nucleotides.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Binding Sites; Calorimetry; Catalytic Domain; DNA-Binding Proteins; Energy Metabolism; Escherichia coli; Kinetics; Magnesium; Nucleotides; Proton-Translocating ATPases; Thermodynamics | 2014 |
Reversal strategy in antagonizing the P2Y12 -inhibitor ticagrelor.
Topics: Adenosine; Adenosine Diphosphate; Adult; Dose-Response Relationship, Drug; Healthy Volunteers; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet-Rich Plasma; Purinergic P2Y Receptor Antagonists; Ticagrelor | 2013 |
Effects of ex vivo platelet supplementation on platelet aggregability in blood samples from patients treated with acetylsalicylic acid, clopidogrel, or ticagrelor.
Topics: Adenosine; Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Peptide Fragments; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Transfusion; Ticagrelor; Ticlopidine | 2014 |
'VASPFix' for measurement of VASP phosphorylation in platelets and for monitoring effects of P2Y12 antagonists.
Topics: Adenosine; Adenosine Diphosphate; Alprostadil; Biomarkers, Pharmacological; Blood Platelets; Bucladesine; Cell Adhesion Molecules; Cells, Cultured; Clopidogrel; Cyclic AMP; Humans; Iloprost; Microfilament Proteins; Phosphoproteins; Phosphorylation; Piperazines; Platelet Aggregation; Platelet Function Tests; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Reproducibility of Results; Sensitivity and Specificity; Thiophenes; Thrombophilia; Ticlopidine | 2014 |
Association of platelet ITGA2B and ITGB3 polymorphisms with ex vivo antiplatelet effect of ticagrelor in healthy Chinese male subjects.
Topics: Adenosine; Adenosine Diphosphate; Adult; Asian People; Cohort Studies; Dose-Response Relationship, Drug; Humans; Integrin alpha2; Integrin beta3; Male; Platelet Aggregation; Polymorphism, Single Nucleotide; Purinergic P2 Receptor Antagonists; Ticagrelor; Young Adult | 2014 |
Neurochemical measurement of adenosine in discrete brain regions of five strains of inbred mice.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Brain; Chromatography, High Pressure Liquid; Electrochemical Techniques; Male; Mice; Mice, 129 Strain; Mice, Inbred BALB C; Mice, Inbred C57BL; Neurotransmitter Agents; Organ Specificity; Reference Standards | 2014 |
The volatile anesthetic isoflurane increases endothelial adenosine generation via microparticle ecto-5'-nucleotidase (CD73) release.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Amides; Anesthetics, Inhalation; Animals; Antigens, CD; Cadherins; Cell Line, Transformed; Cell-Derived Microparticles; Endothelial Cells; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Isoflurane; Kidney Glomerulus; Male; Mice; Mice, Inbred C57BL; Myosin-Light-Chain Phosphatase; Pyridines; rho-Associated Kinases; Signal Transduction | 2014 |
Ob/ob mouse livers show decreased oxidative phosphorylation efficiencies and anaerobic capacities after cold ischemia.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Allopurinol; Anaerobiosis; Animals; Blood Glucose; Body Weight; Buffers; Cell Respiration; Cold Ischemia; Electron Transport; Fasting; Fatty Liver; Glucose Intolerance; Glutathione; Hydrogen-Ion Concentration; Insulin; Insulin Resistance; Liver; Male; Mice, Inbred C57BL; Mice, Obese; Mitochondria, Liver; Organ Preservation Solutions; Oxidative Phosphorylation; Raffinose; Thinness | 2014 |
Effects of airway surface liquid height on the kinetics of extracellular nucleotides in airway epithelia.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Extracellular Space; Humans; Kinetics; Membrane Transport Proteins; Models, Biological; Nucleotides; Receptors, Purinergic P2Y2; Respiratory Mucosa; Surface Properties | 2014 |
2´,3´-Dialdehyde of ATP, ADP, and adenosine inhibit HIV-1 reverse transcriptase and HIV-1 replication.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Anti-HIV Agents; Cells, Cultured; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Macrophages; Virus Replication | 2014 |
Competitive mode and site of interaction of ticagrelor at the human platelet P2Y12 -receptor.
Topics: Adenosine; Adenosine Diphosphate; Animals; Binding Sites; Binding, Competitive; CHO Cells; Colforsin; Cricetulus; Cyclic AMP; Dose-Response Relationship, Drug; Gene Expression Regulation; Genes, Reporter; Humans; Luciferases; Mutation; Platelet Aggregation Inhibitors; Protein Binding; Purinergic P2Y Receptor Agonists; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Response Elements; Thionucleotides; Ticagrelor; Transfection | 2014 |
ADP-induced bladder contractility is mediated by P2Y12 receptor and temporally regulated by ectonucleotidases and adenosine signaling.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphatases; Animals; Electric Stimulation; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle Contraction; Receptors, Purinergic P2Y12; Signal Transduction; Urinary Bladder | 2014 |
Naturally occurring N(6)-substituted adenosines (cytokinin ribosides) are in vitro inhibitors of platelet aggregation: an in silico evaluation of their interaction with the P2Y(12) receptor.
Topics: Adenosine; Adenosine Diphosphate; Blood Platelets; Cytokinins; Humans; In Vitro Techniques; Plant Growth Regulators; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P1 Receptor Agonists; Receptors, Purinergic P2Y12; Ribonucleosides | 2014 |
Role of adenosine signaling on pentylenetetrazole-induced seizures in zebrafish.
Topics: Adenine; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine Diphosphate; Animals; Benzyl Compounds; Convulsants; Dipyridamole; Gene Expression Regulation; Genes, fos; Pentylenetetrazole; Phenethylamines; Phosphodiesterase Inhibitors; Seizures; Signal Transduction; Thioinosine; Xanthines; Zebrafish | 2015 |
The NLRP3 inflammasome is activated by nanoparticles through ATP, ADP and adenosine.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Carrier Proteins; Cell Line; Connexins; Cyclic AMP; Humans; Inflammasomes; Inositol Phosphates; Interleukin-1beta; Macrophages; Mice, Inbred C57BL; Models, Biological; Nanoparticles; Nerve Tissue Proteins; NLR Family, Pyrin Domain-Containing 3 Protein; Pneumonia; Receptors, Purinergic P1; Receptors, Purinergic P2Y; Signal Transduction; Silicon Dioxide; Titanium; Type C Phospholipases | 2015 |
Enzymatic conversion of ATP to adenosine contributes to ATP-induced inhibition of glutamate release in rat medullary dorsal horn neurons.
Topics: Action Potentials; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Male; Patch-Clamp Techniques; Posterior Horn Cells; Purinergic P2X Receptor Agonists; Purinergic P2X Receptor Antagonists; Rats; Rats, Sprague-Dawley | 2015 |
Thrombin generation induced by tissue factor plus ADP in human platelet rich plasma: A potential new measurement to assess the effect of the concomitant use of an oral factor Xa inhibitor edoxaban and P2Y12 receptor antagonists.
Topics: Adenosine; Adenosine Diphosphate; Blood Coagulation; Blood Coagulation Tests; Factor Xa Inhibitors; Humans; Platelet-Rich Plasma; Purinergic P2Y Receptor Antagonists; Pyridines; Thiazoles; Thrombin; Thromboplastin; Ticagrelor | 2015 |
β-Nicotinamide adenine dinucleotide acts at prejunctional adenosine A1 receptors to suppress inhibitory musculomotor neurotransmission in guinea pig colon and human jejunum.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine Diphosphate; Animals; Colon; Deoxyadenine Nucleotides; Electric Stimulation; Guinea Pigs; Humans; Jejunum; Ligands; Membrane Potentials; Muscle Contraction; Muscle, Smooth; NAD; Neuromuscular Junction; Purinergic P2Y Receptor Antagonists; Receptor, Adenosine A1; Synaptic Transmission | 2015 |
Different danger signals differently impact on microglial proliferation through alterations of ATP release and extracellular metabolism.
Topics: 5'-Nucleotidase; Adenosine; Adenosine A2 Receptor Antagonists; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Apyrase; Cell Line; Cell Proliferation; Cells, Cultured; Enzyme Inhibitors; Extracellular Space; Glutamic Acid; Lipopolysaccharides; Mice, Inbred C57BL; Microglia; Pyrimidines; Receptors, Adenosine A2; Triazoles | 2015 |
Influence of P2Y12 polymorphisms on platelet activity but not ex-vivo antiplatelet effect of ticagrelor in healthy Chinese male subjects.
Topics: Adenosine; Adenosine Diphosphate; Adolescent; Adult; Alleles; Asian People; Blood Platelets; Drug Antagonism; Genotype; Healthy Volunteers; Heterotrimeric GTP-Binding Proteins; Humans; Male; Platelet Activation; Platelet Aggregation; Platelet-Rich Plasma; Polymorphism, Single Nucleotide; Primary Cell Culture; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Sequence Analysis, DNA; Ticagrelor | 2015 |
Kinetic mechanism of Toxoplasma gondii adenosine kinase and the highly efficient utilization of adenosine.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Kinase; Adenosine Monophosphate; Adenosine Triphosphate; Binding Sites; Kinetics; Phosphorylation; Substrate Specificity; Toxoplasma | 2015 |
CD73 Activity is Dispensable for the Polarization of M2 Macrophages.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Cytokines; Flow Cytometry; GPI-Linked Proteins; Humans; Immunosuppressive Agents; Inflammation; Interferon-gamma; Interleukin-4; Lipopolysaccharides; Macrophage Colony-Stimulating Factor; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Monocytes; Phenotype | 2015 |
The effectiveness of platelet supplementation for the reversal of ticagrelor-induced inhibition of platelet aggregation: An in-vitro study.
Topics: Adenosine; Adenosine Diphosphate; Arachidonic Acid; Aspirin; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Transfusion; Ticagrelor | 2016 |
Changes in Purines Concentration in the Cerebrospinal Fluid of Pregnant Women Experiencing Pain During Active Labor.
Topics: Adenosine; Adenosine Diphosphate; Adult; Cesarean Section; Female; Guanosine; Guanosine Diphosphate; Humans; Labor Pain; Labor, Obstetric; Male; Pain Measurement; Pain Perception; Pregnancy; Prospective Studies; Purines | 2015 |
ATP release, generation and hydrolysis in exocrine pancreatic duct cells.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Bile Acids and Salts; Cell Line; Humans; Hydrogen-Ion Concentration; L-Lactate Dehydrogenase; Osmolar Concentration; Pancreas, Exocrine; Pancreatic Ducts; Receptors, Purinergic P2X; Receptors, Purinergic P2Y; Stress, Physiological; Uridine Diphosphate; Uridine Triphosphate | 2015 |
Advanced age and high-residual platelet reactivity in patients receiving dual antiplatelet therapy with clopidogrel or ticagrelor.
Topics: Adenosine; Adenosine Diphosphate; Age Factors; Aged; Aged, 80 and over; Aspirin; Blood Platelets; Clopidogrel; Cohort Studies; Female; Humans; Male; Middle Aged; Odds Ratio; Patient Discharge; Percutaneous Coronary Intervention; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prevalence; Thrombosis; Ticagrelor; Ticlopidine; Time Factors | 2016 |
Inter-patient variability of platelet reactivity in patients treated with prasugrel and ticagrelor.
Topics: Acute Coronary Syndrome; Adenosine; Adenosine Diphosphate; Aged; Biomarkers; Blood Platelets; Female; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Prospective Studies; Risk Factors; Ticagrelor; Treatment Outcome | 2016 |
Fibrinogen γ-Chain Peptide-Coated Adenosine 5' Diphosphate-Encapsulated Liposomes Rescue Mice From Lethal Blast Lung Injury via Adenosine Signaling.
Topics: Adenosine; Adenosine Diphosphate; Animals; Blast Injuries; Disease Models, Animal; Fibrinogen; Liposomes; Lung Injury; Male; Mice; Mice, Inbred C57BL; Oligopeptides; Platelet Aggregation Inhibitors; Signal Transduction | 2016 |
Parathyroid Hormone Levels and High-Residual Platelet Reactivity in Patients Receiving Dual Antiplatelet Therapy With Acetylsalicylic Acid and Clopidogrel or Ticagrelor.
Topics: Acute Coronary Syndrome; Adenosine; Adenosine Diphosphate; Aged; Aspirin; Biomarkers; Clopidogrel; Coronary Artery Disease; Databases, Factual; Drug Resistance; Drug Therapy, Combination; Female; Homeodomain Proteins; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Risk Factors; Ticagrelor; Ticlopidine; Time Factors; Transcription Factors; Treatment Outcome; Up-Regulation | 2016 |
Effect of Cardiovascular Injury on Catabolism of Adenosine and Adenosine 5-'Triphosphate in Systemic Blood in a Freely Moving Rat Model In Vivo.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cardiovascular Diseases; Disease Models, Animal; Hypoxanthine; Isoproterenol; Rats; Rats, Sprague-Dawley; Uric Acid | 2016 |
Role of the CD39/CD73 Purinergic Pathway in Modulating Arterial Thrombosis in Mice.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Arterial Occlusive Diseases; Blood Coagulation; Bone Marrow Transplantation; Chlorides; Disease Models, Animal; Endothelial Cells; Ferric Compounds; Genetic Predisposition to Disease; HEK293 Cells; Humans; Hydrolysis; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Monocytes; Phenotype; Platelet Activation; Thrombosis; Time Factors; Transfection | 2016 |
A Comparative Study of Vasorelaxant Effects of ATP, ADP, and Adenosine on the Superior Mesenteric Artery of SHR.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood Pressure; Endothelium, Vascular; Hypertension; Male; Mesenteric Artery, Superior; Rats, Inbred SHR; Rats, Inbred WKY; Vasodilator Agents | 2016 |
Vitamin D levels and high-residual platelet reactivity in patients receiving dual antiplatelet therapy with clopidogrel or ticagrelor.
Topics: Adenosine; Adenosine Diphosphate; Aged; Aged, 80 and over; Biomarkers; Blood Platelets; Clopidogrel; Comorbidity; Coronary Angiography; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Odds Ratio; Platelet Activation; Platelet Aggregation Inhibitors; Ticagrelor; Ticlopidine; Vitamin D | 2016 |
Preoperative platelet function predicts perioperative bleeding complications in ticagrelor-treated cardiac surgery patients: a prospective observational study.
Topics: Adenosine; Adenosine Diphosphate; Aged; Aged, 80 and over; Blood Platelets; Cardiac Surgical Procedures; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Transfusion; Postoperative Hemorrhage; Prospective Studies; Purinergic P2Y Receptor Antagonists; Ticagrelor | 2016 |
Deregulation of ocular nucleotide homeostasis in patients with diabetic retinopathy.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adenylate Kinase; Adult; Aged; Chromatography, Thin Layer; Diabetic Retinopathy; Erythropoietin; Female; Humans; Male; Middle Aged; Nucleoside-Diphosphate Kinase; Retina; Statistics, Nonparametric; Vascular Endothelial Growth Factor A; Vitreous Body | 2017 |
Inverse agonism at the P2Y12 receptor and ENT1 transporter blockade contribute to platelet inhibition by ticagrelor.
Topics: Adenosine; Adenosine Diphosphate; Blood Platelets; Calcium; Calcium Signaling; Cell Adhesion Molecules; Colforsin; Cyclic AMP; Equilibrative Nucleoside Transporter 1; Female; Humans; Male; Microfilament Proteins; Phosphoproteins; Phosphorylation; Platelet Activation; Receptors, Purinergic P2Y12; Ticagrelor | 2016 |
Switching of adenosine diphosphate receptor inhibitor after hospital discharge among myocardial infarction patients: Insights from the Treatment with Adenosine Diphosphate Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events after
Topics: Adenosine; Adenosine Diphosphate; Aged; Cardiovascular Diseases; Clopidogrel; Drug Substitution; Female; Hemorrhage; Humans; Longitudinal Studies; Male; Middle Aged; Myocardial Infarction; Patient Discharge; Patient Preference; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P1 Receptor Antagonists; Ticagrelor; Ticlopidine | 2017 |
Purinergic enzymatic activities in lymphocytes and cardiomyocytes of mice acutely infected by Trypanosoma cruzi modulating the inflammatory responses.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Chagas Disease; Disease Models, Animal; Female; Heart; Hematologic Tests; Hydrolysis; Lymphocytes; Mice; Myocardium; Myocytes, Cardiac; Parasitemia; Purines; Trypanosoma cruzi | 2017 |
Hemostatic effects of the ticagrelor antidote MEDI2452 in pigs treated with ticagrelor on a background of aspirin.
Topics: Adenosine; Adenosine Diphosphate; Animals; Antibodies, Neutralizing; Antidotes; Aspirin; Biotinylation; Blood Pressure; Broadly Neutralizing Antibodies; Hemorrhage; Hemostasis; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Swine; Ticagrelor; Time Factors | 2017 |
New insights on the regulation of the adenine nucleotide pool of erythrocytes in mouse models.
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; AMP Deaminase; Animals; Calcium; Cholestenones; Dipyridamole; Dose-Response Relationship, Drug; Equilibrative Nucleoside Transporter 1; Erythrocytes; Mice, Knockout; Oxygen; Time Factors | 2017 |
Extracellular adenosine produced by ecto-5'-nucleotidase (CD73) regulates macrophage pro-inflammatory responses, nitric oxide production, and favors Salmonella persistence.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Cytokines; Host-Pathogen Interactions; Inflammation; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type II; RAW 264.7 Cells; Salmonella Infections; Salmonella typhimurium | 2018 |
Decreased platelet inhibition by P2Y12 receptor blockers in anaemia.
Topics: Adenosine; Adenosine Diphosphate; Aged; Anemia; Angioplasty; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Monocytes; P-Selectin; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Stents; Ticagrelor; Ticlopidine | 2018 |
Adenosine Production by Biomaterial-Supported Mesenchymal Stromal Cells Reduces the Innate Inflammatory Response in Myocardial Ischemia/Reperfusion Injury.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Cells, Cultured; Coculture Techniques; Disease Models, Animal; Enzyme Inhibitors; GPI-Linked Proteins; Humans; Hydrogen Peroxide; Immunity, Innate; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Neutrophils; Rats, Sprague-Dawley; Recovery of Function; Stem Cell Niche; Tissue Scaffolds | 2018 |
The effects of adenine nucleotide perfusion on interstitial adenosine production in rat skeletal muscle.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Male; Microdialysis; Muscle, Skeletal; Perfusion; Rats, Sprague-Dawley | 2018 |
Caffeine and high intensity exercise: Impact on purinergic and cholinergic signalling in lymphocytes and on cytokine levels.
Topics: Acetylcholinesterase; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Caffeine; Cell Proliferation; Cytokines; Glucocorticoids; Hydrolysis; Lymphocyte Activation; Lymphocytes; Male; Physical Conditioning, Animal; Rats, Wistar; Receptors, Cholinergic; Receptors, Purinergic; Signal Transduction | 2018 |
Soluble and membrane-bound adenylate kinase and nucleotidases augment ATP-mediated inflammation in diabetic retinopathy eyes with vitreous hemorrhage.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adenylate Kinase; Adult; Aged; Alkaline Phosphatase; Diabetic Retinopathy; Eye; Female; Humans; Inflammation; Male; Middle Aged; Nucleotidases; Vitreous Hemorrhage | 2019 |
Enhanced ATP release and CD73-mediated adenosine formation sustain adenosine A
Topics: 5'-Nucleotidase; Adenosine; Adenosine A2 Receptor Antagonists; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cell Line, Tumor; Humans; Male; Oxidopamine; Parkinsonian Disorders; Pyrimidines; Rats, Wistar; Receptor, Adenosine A2A; Triazoles | 2019 |
Participation of the adenosine salvage pathway and cyclic AMP modulation in oocyte energy metabolism.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Bucladesine; Coculture Techniques; Colforsin; Cumulus Cells; Cyclic AMP; Energy Metabolism; Female; Gap Junctions; Gene Expression; In Vitro Oocyte Maturation Techniques; Meiosis; Mice; Oocytes | 2019 |
Structure and ligand binding of the ADP-binding domain of the NAD
Topics: Adenosine; Adenosine Diphosphate; Base Pairing; Hydrogen Bonding; Ligands; NAD; Nucleic Acid Conformation; Riboswitch; RNA | 2020 |
Compartmentalization of adenosine metabolism in cancer cells and its modulation during acute hypoxia.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adenylate Kinase; Animals; Hypoxia; Male; Mice; Neoplasms; Nucleotides | 2020 |
Characterization of the N
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Male; Nucleotidases; Purine-Nucleoside Phosphorylase; Rats | 2020 |
Biochemical analysis of ectonucleotidases on primary rat vascular smooth muscle cells and in silico investigation of their role in vascular diseases.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Antigens, CD; Aorta; Apyrase; Computer Simulation; GPI-Linked Proteins; Mice; Muscle, Smooth, Vascular; Nucleotides; Rats; Rats, Wistar; Vascular Diseases | 2020 |
Extracellular Adenine Nucleotides and Adenosine Modulate the Growth and Survival of THP-1 Leukemia Cells.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Affinity Labels; Apoptosis; Cell Cycle; Cell Movement; Cell Proliferation; Extracellular Matrix; Humans; Leukemia, Myeloid, Acute; Thionucleotides; Tumor Cells, Cultured | 2020 |
e5NT inhibitor protects acute restraint stress-induced depression by regulating nucleoside release in mice.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Elevated Plus Maze Test; Enzyme Inhibitors; Exploratory Behavior; GPI-Linked Proteins; Hippocampus; Male; Mice; Open Field Test; Restraint, Physical; Stress, Psychological; Uridine | 2020 |
Cardiolipin, conformation, and respiratory complex-dependent oligomerization of the major mitochondrial ADP/ATP carrier in yeast.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Cardiolipins; Mitochondrial ADP, ATP Translocases; Saccharomyces cerevisiae | 2020 |
Cilostazol increases adenosine plasma concentration in patients with acute coronary syndrome.
Topics: Acute Coronary Syndrome; Adenosine; Adenosine Diphosphate; Aged; Aspirin; China; Cilostazol; Clopidogrel; Cyclic AMP; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Function Tests | 2021 |
Inhibition of ecto-5'-nucleotidase and adenosine deaminase is able to reverse long-term behavioural effects of early ethanol exposure in zebrafish (Danio rerio).
Topics: 5'-Nucleotidase; Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Animals; Antisocial Personality Disorder; Behavior, Animal; Disease Models, Animal; Ethanol; Female; Humans; Pregnancy; Prenatal Exposure Delayed Effects; Social Interaction; Zebrafish | 2020 |
Atomistic basis of force generation, translocation, and coordination in a viral genome packaging motor.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphatases; Arginine; Bacillus Phages; Catalytic Domain; Crystallography, X-Ray; Molecular Dynamics Simulation; Phosphates; Protein Structure, Quaternary; Protein Structure, Tertiary; Protein Subunits; Viral Genome Packaging; Viral Proteins | 2021 |
Clinical validation of AggreGuide A-100 ADP, a novel assay for assessing the antiplatelet effect of oral P2Y
Topics: Adenosine; Adenosine Diphosphate; Blood Platelets; Clopidogrel; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Prospective Studies; Purinergic P2Y Receptor Antagonists; Ticagrelor | 2021 |
DNAse-dependent, NET-independent pathway of thrombus formation in vivo.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood Platelets; Deoxyribonuclease I; Extracellular Traps; Fibrin; Humans; Hydrolysis; Lasers; Leukocyte Elastase; Mice, Inbred C57BL; Models, Biological; Neutrophil Activation; Neutrophils; Platelet Activation; Protein-Arginine Deiminase Type 4; Thrombosis | 2021 |
Crowding within synaptic junctions influences the degradation of nucleotides by CD39 and CD73 ectonucleotidases.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Apyrase; Synapses | 2022 |
Optimized HPLC method to elucidate the complex purinergic signaling dynamics that regulate ATP, ADP, AMP, and adenosine levels in human blood.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Chromatography, High Pressure Liquid; Edetic Acid; Humans | 2022 |
Tannic Acid Attenuates Peripheral and Brain Changes in a Preclinical Rat Model of Glioblastoma by Modulating Oxidative Stress and Purinergic Signaling.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antioxidants; Brain; Glioblastoma; Nitrites; Oxidative Stress; Rats; Reactive Oxygen Species; Superoxide Dismutase; Tannins; Thiobarbituric Acid Reactive Substances | 2022 |
Being Overweight or Obese Is Associated with an Increased Platelet Reactivity Despite Dual Antiplatelet Therapy with Aspirin and Clopidogrel.
Topics: Adenosine; Adenosine Diphosphate; Aspirin; Blood Platelets; Clopidogrel; Humans; Obesity; Overweight; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticagrelor; Ticlopidine | 2023 |
Elevated Serum Purine Levels in Schizophrenia: A Reverse Translational Study to Identify Novel Inflammatory Biomarkers.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Biomarkers; Humans; Interleukin-12; Interleukin-1beta; Interleukin-6; Purines; Schizophrenia | 2022 |
Syncope without prodromes is associated with excessive plasma release of adenosine at the time of syncope during head-up tilt table test.
Topics: Adenosine; Adenosine Diphosphate; Humans; Syncope; Syncope, Vasovagal; Tilt-Table Test | 2022 |
Effect of endogenous purines on electrically evoked ACh release at the mouse neuromuscular junction.
Topics: Acetylcholine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Mice; Neuromuscular Junction; Receptors, Purinergic P1 | 2022 |
Hydrolysis rate constants of ATP determined in situ at elevated temperatures.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Carbon; Diamond; Hydrolysis; Kinetics; Phosphates; Temperature | 2022 |
Construction of enzyme-laden vascular scaffolds based on hyaluronic acid oligosaccharides-modified collagen nanofibers for antithrombosis and in-situ endothelialization of tissue-engineered blood vessels.
Topics: Adenosine; Adenosine Diphosphate; Blood Vessel Prosthesis; Collagen; Fibrinolytic Agents; Hyaluronic Acid; Nanofibers; Oligosaccharides; Tissue Engineering; Tissue Scaffolds | 2022 |
Platelets and the Cybernetic Regulation of Ischemic Inflammatory Responses through PNC Formation Regulated by Extracellular Nucleotide Metabolism and Signaling.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Antibodies, Blocking; Blood Platelets; Cell Adhesion Molecules; Cybernetics; Humans; Ischemia; Neutrophils | 2022 |
Dysfunctional purinergic signaling correlates with disease severity in COVID-19 patients.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; COVID-19; Humans; Purines; Severity of Illness Index; Signal Transduction | 2022 |
Elevated serum C1q is an independent predictor of high residual platelet reactivity in CAD patients receiving clopidogrel therapy.
Topics: Adenosine; Adenosine Diphosphate; Clopidogrel; Complement C1q; Coronary Artery Disease; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Thrombosis; Ticagrelor; Ticlopidine | 2022 |
Mammalian N1-adenosine PARylation is a reversible DNA modification.
Topics: Adenosine; Adenosine Diphosphate; Animals; Chromatography, Liquid; Deoxyadenosines; DNA; DNA, Single-Stranded; Glycoside Hydrolases; Mammals; Poly (ADP-Ribose) Polymerase-1; Poly Adenosine Diphosphate Ribose; Poly ADP Ribosylation; Poly(ADP-ribose) Polymerase Inhibitors; Tandem Mass Spectrometry | 2022 |
Platelet function testing using the Multiplate analyzer after administration of aspirin in Aachen minipigs.
Topics: Adenosine; Adenosine Diphosphate; Animals; Arachidonic Acid; Aspirin; Blood Platelets; Diphosphates; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Receptors, Thrombin; Swine; Swine, Miniature | 2022 |
High-Intensity Exercise Training Improves Basal Platelet Prostacyclin Sensitivity and Potentiates the Response to Dual Anti-Platelet Therapy in Postmenopausal Women.
Topics: Adenosine; Adenosine Diphosphate; Aspirin; Cyclooxygenase 1; Diphosphates; Dual Anti-Platelet Therapy; Epoprostenol; Estrogens; Exercise; Female; Humans; Nitric Oxide; Peptides; Platelet Aggregation Inhibitors; Postmenopause; Receptors, Epoprostenol; Receptors, Thromboxane; Thrombin; Thrombosis; Thromboxanes | 2022 |
ATPergic signaling disruption in human sepsis as a potential source of biomarkers for clinical use.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Apyrase; Biomarkers; Humans; Sepsis; Shock, Septic | 2023 |
Involvement of P2Y
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cerebral Cortex; N-Methylaspartate; Norepinephrine; Rats; Rats, Wistar | 2023 |
Ticagrelor inverse agonist activity at the P2Y
Topics: Acute Coronary Syndrome; Adenosine; Adenosine Diphosphate; Blood Platelets; Diphosphates; Drug Inverse Agonism; Humans; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Ticagrelor | 2024 |
Metal/ADP Complexes Promote Phosphorylation of Ribonucleotides.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Coordination Complexes; Phosphorylation; Ribonucleotides; Water | 2023 |