Page last updated: 2024-08-17

adenosine diphosphate and adenosine 5'-methylenediphosphate

adenosine diphosphate has been researched along with adenosine 5'-methylenediphosphate in 164 studies

Research

Studies (164)

TimeframeStudies, this research(%)All Research%
pre-199042 (25.61)18.7374
1990's56 (34.15)18.2507
2000's37 (22.56)29.6817
2010's24 (14.63)24.3611
2020's5 (3.05)2.80

Authors

AuthorsStudies
Bhave, DP; Carroll, KS; Hong, JA1
Abdelrahman, A; Bhattarai, S; El-Tayeb, A; Freundlieb, M; Idris, R; Lee, SY; Müller, CE; Pippel, J; Renn, C; Rolshoven, G; Scaletti, E; Sträter, N; Zimmermann, H1
Shank, RP1
Späth, L; Starke, K; von Kügelgen, I1
Berne, RM; Headrick, JP; Matherne, GP1
Chen, SS; Lin, YT; Wu, SN1
Amerini, S; Ledda, F; Mantelli, L; Rubino, A1
Cunha, RA; Sebastião, AM1
Burnstock, G; Maynard, KI; Saville, VL1
Borst, MM; Schrader, J1
Cahill, BE; Haile, DM; Kadowitz, PJ; Neely, CF1
Ardito, T; Gaudio, KM; Kashgarian, M; Siegel, NJ; Thulin, G1
Bertrand, G; Gross, R; Loubatières-Mariani, MM; Ribes, G1
Flocke, K; Mannherz, HG1
Chen, G; Suzuki, H1
Kather, H1
Belardinelli, L; Boykin, MT; Hill, JA; Shryock, JC1
Dieckhoff, J; Elsässer, K; Mannherz, HG; Risse, G; Stochaj, U; von der Mark, K1
Gaudio, KM; Kashgarian, M; Shulman, RG; Siegel, NJ; Stromski, ME; Thulin, G; Van Waarde, A1
Deussen, A; Möser, GH; Schrader, J1
Dubach, UC; Gandhi, R; Le Hir, M1
Chin, WP; Imai, S; Jin, H; Nakazawa, M1
Loubatières-Mariani, MM; Manteghetti, M; Petit, P1
Bianchi, A; Boccadoro, M; Dianzani, U; Massaia, M; Palumbo, A; Pileri, A1
Berne, RM; Meghji, P; Rubio, R1
Fraser, LR; Monks, NJ1
Ikegami, T; Natsumeda, Y; Weber, G1
Burnstock, G; Hoyle, CH1
Bertrand, G; Chapal, J; Gross, R; Loubatières-Mariani, MM1
Lowenstein, JM; Naito, Y1
Costa, M; Furness, JB; Humphreys, CM1
Joost, HG; Steinfelder, HJ1
Bukoski, RD; Sparks, HV1
Edwards, NL; Renard, GA; Zaytoun, AM1
Cartner, LA; Holliss, DG; Humphrey, SM1
Muramatsu, I1
Blakeley, AG; Dunn, PM1
Cohen, RA; Zitnay, KM1
Bertrand, G; Chapal, J; Loubatieres-Mariani, MM1
Loubatieres-Mariani, MM; Manteghetti, M; Petit, P; Puech, R1
Kupriianov, VV; Ruuge, EK; Saks, VA; Shteĭnshneĭder, AIa1
Ito, Y; Kimoto, Y1
Burnstock, G; Reilly, WM; Saville, VL1
Ehinger, BE; Fredholm, BB; Lindström, K; Perez, MT1
Fuchs, BD; Gorman, MW; Sparks, HV1
Belloni, FL; Elkin, PL; Giannotto, B1
Burnstock, G; Mathieson, JJ1
Peters, TJ; Shah, T; Webster, AD1
Chapal, J; Loubatières-Mariani, MM; Roye, M; Zerbib, A1
Fredholm, BB; Jonzon, B; Lindgren, E; Lindström, K1
Horak, A; Jain, JC1
Aubry, J; Paraf, A; Pommier, P; Potter, M; Simonin, G; Singh, SN; Zachowski, A1
Edwards, NL; Fox, IH; Manfredi, J; Recker, D; Rembecki, R1
Casteel, NL; Kemp, RG; Menahan, LA1
Maire, JC; Medilanski, J; Straub, RW1
Kille, JM; Klabunde, RE1
Milner-White, EJ; Rycroft, DS1
Burt, CT; Labotka, RJ; Schliselfeld, LH1
Stone, TW1
Heilbronn, A; Zimmermann, H1
Downey, HF; Fan, WL; Gao, ZP; Mallet, RT1
Starke, K; Stoffel, D; von Kügelgen, I1
Hori, M; Itoh, T; Iwakura, K; Kitakaze, M; Komamura, K; Minamino, T; Morioka, T; Node, K; Okazaki, Y; Takashima, S1
Hassinen, IE; Peuhkurinen, KJ; Raatikainen, MJ1
Redman, RS; Silinsky, EM1
Chujo, M; Hori, M; Inoue, M; Kitakaze, M; Minamino, T; Mori, H; Morioka, T; Sato, H; Shinozaki, Y; Takashima, S1
Baldwin, JC; Braxton, J; Condos, S; Kopf, GS; Lobdell, KW; Schwann, TA1
Fabiani, R; Ronquist, G1
Awtrey, CS; Colgan, SP; Delp-Archer, C; Madara, JL; Mrsny, RJ; Patapoff, TW; Resnick, MB; Weller, PF1
Sakakibara, Y1
Fredholm, BB; Lindström, K; Lloyd, HG1
Franklin, PH; Murray, TF; Zhang, G1
Chau, NM; Fan, TP; Frost, EE; Humphrey, PP; Michel, AD1
Bengtsson, T; Grenegård, M; Stendahl, O; Zalavary, S1
Bela Agostinho, A; Carlucci, F; Francini, G; Marinello, E; Pagani, R; Petrioli, R; Pizzichini, M; Rosi, F; Tabucchi, A; Vannoni, D1
Culic, O; Lemmens, R; Teuchy, H; Vanduffel, L1
Hori, M; Inoue, M; Kamada, T; Kitakaze, M; Komamura, K; Minamino, T; Morioka, T; Node, K; Takeda, H1
Cunha, RA; Ribeiro, JA; Sebastião, AM; Vizi, ES1
Marshall, JM; Skinner, MR1
Hori, M; Inoue, M; Kamada, T; Kitakaze, M; Komamura, K; Minamino, T; Node, K1
Berleth, ES; Ehrke, MJ; Kitano, H; Mihich, E; Pietkiewicz, JM; Skaar, JR; Ujházy, P1
de Jong, JW; Seymour, AM; Skladanowski, AC; Smolenski, RT; Tavenier, M; Yacoub, MH1
Burnstock, G; Spyer, KM; St Lambert, JH; Thomas, T1
Funaya, H; Hori, M; Kitakaze, M; Minamino, T; Mori, H; Node, K; Shinozaki, Y1
Koch, H; Starke, K; von Kügelgen, I1
Brause, M; Delabar, U; Eckardt, KU; Gleiter, CH; Zebski, H1
Oliveira, CR; Rego, AC; Santos, MS1
Arita, M; Obata, T; Sato, T; Yamanaka, Y1
Ito, T; Mokuno, S; Murase, K; Okumura, K; Shinoda, M; Toki, Y1
Hendrickson, WA; Klein, MG; Lima, CD1
Kokubun, S; Naramatsu, M; Yamashita, T1
Brundege, JM; Diao, L; Dunwiddie, TV; Proctor, WR1
Funaya, H; Hori, M; Kitakaze, M; Komamura, K; Kurihara, T; Minamino, T; Node, K; Ueda, Y1
Koos, BJ; Kruger, L; Murray, TF1
Asanuma, H; Funaya, H; Hori, M; Kitakaze, M; Kuzuya, T; Minamino, T; Sato, H; Ueda, Y1
Pangalis, GA; Tsavaris, NB1
Bünger, R; Miki, T; Miura, T; Sakamoto, J; Shimamoto, K; Suzuki, K1
Chessell, IP; Hicks, GA; Humphrey, PP; Sansum, AJ; Trezise, DJ1
Chen, SA; Jan, CR; Li, HF; Wu, SN1
Habuchi, Y; Morikawa, J; Nishio, M; Tanaka, H; Yamamoto, T1
Brendel, P; Cunha, RA; Ribeiro, JA; Zimmermann, H1
Chen, CF; Chien, CT; Lin, TB; Yu, HJ1
Obata, T; Yamanaka, Y1
Nikbakht, MR; Stone, TW1
Bentsen, AK; Eriksen, TA; Harlow, KW; Kadziola, A; Larsen, S1
Kaneda, Y; Kitakaze, M; Matsuda, H; Nishimura, M; Sakaguchi, T; Sawa, Y; Suzuki, K1
Belardinelli, L; Erga, KS; Liang, HX; Seubert, CN; Shryock, JC; Wu, L1
Matsuki, N; Nakazawa, K; Ohno, Y; Sato, K1
Kimura, J; Matsuoka, I; Ohkubo, S1
Geiger, JD; Mackiewicz, M; Pack, AI1
Knöfel, T; Sträter, N1
Boegehold, MA; Sauls, BA1
Chen, YF; Li, PL; Zou, AP1
Bültmann, R; Klebroff, W; Starke, K1
Imamura, H; Kido, M; Lu, K; Ninomiya, H; Otani, H; Uchiyama, T1
Hasebe, N; Jin, YT; Kawabe, J; Kikuchi, K; Matsusaka, T1
Mihaylova-Todorova, ST; Todorov, LD; Westfall, DP1
Bulmer, D; Dale, N; Gourine, AV; Llaudet, E; Spyer, KM; Thomas, T1
Bernard, EA; de Souza, LF; Gelain, DP1
Antunes Soares, FA; Dall'Onder, LP; Frizzo, ME; Lara, DR; Souza, DO; Swanson, RA1
Huang, MH; Liu, SI; Wu, SN1
Farina, M; Frizzo, ME; Lara, DR; Portela, LV; Schmidt, AP; Soares, FA; Souza, DO; Tavares, RG1
Conde, SV; Monteiro, EC1
Hellsten, Y; Jensen, L; Schjerling, P1
Liu, XJ; Parkinson, FE; Reid, AR; Sawynok, J1
Chen, S; Li, X; Ou, Z; Shao, Z; Wang, L; Yin, L; Zhi, X; Zhou, P; Zhou, T1
Chen, S; Ou, Z; Shao, Z; Yin, L; Zhao, F; Zhi, X; Zhou, P; Zhou, X1
Angielski, S; Dzierzko, G; Karczewska, J; Martyniec, L; Stepiński, J1
Battastini, AM; Bernardi, A; Braganhol, E; Tamajusuku, AS; Wink, MR1
Chen, S; Ma, D; Ou, Z; Shao, Z; Wang, L; Yin, L; Zhi, X; Zhou, P; Zhou, T; Zhou, X1
Eckle, T; Eltzschig, HK; Gleiter, CH; Grenz, A; Kloor, D; Köhle, C; Osswald, H; Schnermann, J; Vallon, V; von Wietersheim, S; Weingart, J; Zhang, H1
Colgan, SP; Karhausen, J; Louis, NA; MacManus, CF; Robinson, AM; Scully, M1
Eltzschig, HK; Gorzolla, IC; Hart, ML; Henn, M; Kloor, D; Köhler, D; Mittelbronn, M; Stahl, GL1
Caldwell, CC; Lentsch, AB1
Barajas-Espinosa, AR; Chisholm, SP; deVries, M; Lomax, AE; Neshat, S; Skeith, L1
Mohlin, C; Nilsson, M; Persson, K; Säve, S1
Antonilli, L; Brusadin, V; Catalano, M; Chece, G; Cipriani, R; Eusebi, F; Fredholm, BB; Lauro, C; Limatola, C; Trettel, F; van Rooijen, N1
Elima, K; Jalkanen, S; Karikoski, M; Laurila, JP; Marttila-Ichihara, F; Niemelä, J; Salmi, M; Yegutkin, GG1
Curiel, TJ; Fan, J; Shin, T; Thompson, LF; Wang, L; Zhang, B; Zhang, Y1
Boeck, CR; Calo', G; de Andrade, VM; Gavioli, EC; Guerrini, R; Mendonça, BP; Pacheco, R; Pescador, BB; Ramos, SF1
Barrios, CH; Bavaresco, L; Bueno Morrone, F; Cappellari, AR; Fernandes Farias, P; Oliveira Battastini, AM; Rockenbach, L1
Liu, W; Lovatt, D; Nedergaard, M; Schnermann, J; Smith, NA; Takano, T; Tieu, K; Xu, Q1
Adcock, IM; Arra, C; Cicala, C; Forte, G; Luciano, A; Maiolino, P; Montinaro, A; Morello, S; Pinto, A; Sorrentino, R1
Gillespie, DG; Jackson, EK1
Wang, Y; Yin, L; Yu, J; Zhang, L; Zhi, X; Zhou, P1
El-Tayeb, A; Knapp, K; Müller, CE; Pippel, J; Sträter, N; Zebisch, M1
Duda, GN; Gaetjen, M; Geissler, S; Kurtz, A; Ode, A; Ode, JE; Schoon, J1
Bendel, P; Jung, S; Kalchenko, V; Kim, KW; Klein, E; Lira, SA; London, A; Miller, O; Rosenzweig, N; Ruckh, J; Schwartz, M; Shechter, R; Yovel, G1
Bigda, JJ; Gołuńska, M; Kolasa, J; Koszałka, P; Pryszlak, A; Składanowski, AC; Stasiłojć, G1
Brown, KM; Ham, A; Kim, KY; Kim, M; Lee, HT1
Bogo, MR; Bonan, CD; Capiotti, KM; da Costa Schaefer, I; Da Silva, RS; Frantz, JZ; Kist, LW; Menezes, FP; Siebel, AM1
Cristóvão, G; Cunha, RA; George, J; Gomes, CA; Gonçalves, FQ; Gonçalves, T; Meyer Fernandes, JR; Rodrigues, L1
Bogo, MR; Capiotti, KM; da Silva, CS; da Silva, NL; Da Silva, RS; Kist, LW; Lutte, AH1
Abdelrahman, A; Bhattarai, S; El-Tayeb, A; Fiene, A; Freundlieb, M; Lee, SY; Meyer, A; Müller, CE; Pippel, J; Sträter, N; Yegutkin, GG; Zimmermann, H1
Eichin, D; Jalkanen, S; Laurila, JP; Salmi, M1
Alam, MS; Cavanaugh, C; Costales, MG; Williams, KM1
Deppen, J; García, AJ; Levit, RD; Shin, EY; Strobel, F; Tirouvanziam, R; Wang, L; Xu, K; Zemskova, M1
Mierzejewska, P; Slominska, EM; Smolenski, RT; Tomczyk, M1
Agostinho, P; Andrade, GM; Canas, PM; Carmo, M; Cunha, RA; Duarte, FV; Fernandes, FD; Gonçalves, FQ; Oses, JP; Palmeira, CM; Tomé, AR1
Dziodzio, J; Eldridge, A; Emery, IF; Ichinose, F; Leclerc, A; Lord, C; Lucas, FL; May, T; McCrum, B; Riker, R; Robich, MP; Ryzhov, S; Sawyer, DB; Seder, DB1
Bai, X; Liu, P; Zhou, L; Zhu, L1
Aalkjaer, C; Bek, T; Ernst, C; Skov Jensen, P1
Da Silva, RS; Lutte, AH; Majolo, JH1
Dai, JW; Jia, WQ; Liu, ZN; Lv, XW; Zang, DD; Zhang, YF; Zhou, TC1

Other Studies

164 other study(ies) available for adenosine diphosphate and adenosine 5'-methylenediphosphate

ArticleYear
Identification of critical ligand binding determinants in Mycobacterium tuberculosis adenosine-5'-phosphosulfate reductase.
    Journal of medicinal chemistry, 2009, Sep-10, Volume: 52, Issue:17

    Topics: Catalytic Domain; Drug Design; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Ligands; Magnesium; Models, Molecular; Mycobacterium tuberculosis; Oxidoreductases Acting on Sulfur Group Donors; Pseudomonas aeruginosa; Static Electricity; Substrate Specificity

2009
2-Substituted α,β-Methylene-ADP Derivatives: Potent Competitive Ecto-5'-nucleotidase (CD73) Inhibitors with Variable Binding Modes.
    Journal of medicinal chemistry, 2020, 03-26, Volume: 63, Issue:6

    Topics: 5'-Nucleotidase; Adenosine Diphosphate; Animals; Crystallography, X-Ray; Enzyme Inhibitors; GPI-Linked Proteins; Humans; Molecular Docking Simulation; Protein Binding; Rats; Structure-Activity Relationship

2020
Adenosine 5'-monophosphate transport across the membrane of synaptosomes and myelin.
    Neurochemical research, 1992, Volume: 17, Issue:5

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Biological Transport; Female; Guanosine Monophosphate; Guinea Pigs; Kinetics; Male; Membrane Potentials; Myelin Sheath; Osmolar Concentration; Rats; Rats, Inbred Strains; Synaptic Membranes; Synaptosomes; Temperature

1992
Stable adenine nucleotides inhibit [3H]-noradrenaline release in rabbit brain cortex slices by direct action at presynaptic adenosine A1-receptors.
    Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 346, Issue:2

    Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cerebral Cortex; Drug Interactions; Drug Stability; Electric Stimulation; Female; Male; Nerve Endings; Norepinephrine; Purinergic Antagonists; Rabbits; Receptors, Purinergic; Suramin; Synapses; Theophylline; Tritium; Xanthines

1992
Myocardial adenosine formation during hypoxia: effects of ecto-5'-nucleotidase inhibition.
    Journal of molecular and cellular cardiology, 1992, Volume: 24, Issue:3

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Guinea Pigs; Heart; Hypoxia; In Vitro Techniques; Male; Myocardium; Perfusion; Vascular Resistance

1992
Evidence of direct activation of adenosine A1 receptor by 5'-adenosine monophosphate in isolated guinea pig atrial myocytes.
    The Japanese journal of physiology, 1992, Volume: 42, Issue:1

    Topics: Action Potentials; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Atrial Function; Guinea Pigs; Heart Atria; In Vitro Techniques; Isoproterenol; Membrane Potentials; Myocardium; Receptors, Purinergic

1992
ATP modulates the efferent function of capsaicin-sensitive neurones in guinea-pig isolated atria.
    British journal of pharmacology, 1992, Volume: 105, Issue:3

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Guinea Pigs; Heart Atria; In Vitro Techniques; Male; Neurons, Efferent; Receptors, Purinergic; Suramin; Theophylline

1992
Extracellular metabolism of adenine nucleotides and adenosine in the innervated skeletal muscle of the frog.
    European journal of pharmacology, 1991, May-02, Volume: 197, Issue:1

    Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cations; Coformycin; Dipyridamole; In Vitro Techniques; Inosine Monophosphate; Kinetics; Muscles; Piperazines; Rana ridibunda; Sodium-Potassium-Exchanging ATPase; Thioinosine

1991
Sensory-motor neuromodulation of sympathetic vasoconstriction in the rabbit central ear artery.
    European journal of pharmacology, 1990, Oct-09, Volume: 187, Issue:2

    Topics: Adenosine Diphosphate; Animals; Calcitonin Gene-Related Peptide; Catecholamines; Ear; Electric Stimulation; Fluorescence; Histocytochemistry; In Vitro Techniques; Male; Microscopy, Fluorescence; Motor Neurons; Muscle Contraction; Muscle, Smooth, Vascular; Neurons, Afferent; Rabbits; Regional Blood Flow; Staining and Labeling; Substance P; Sympathetic Nervous System; Synaptic Transmission; Vasoconstriction

1990
Adenine nucleotide release from isolated perfused guinea pig hearts and extracellular formation of adenosine.
    Circulation research, 1991, Volume: 68, Issue:3

    Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Coronary Disease; Extracellular Space; Female; Guinea Pigs; Hemodynamics; Isoproterenol; Myocardium; Oxygen; Partial Pressure; Perfusion

1991
Adenosine and ATP produce vasoconstriction in the feline pulmonary vascular bed by different mechanisms.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 258, Issue:3

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cats; Cyclooxygenase Inhibitors; Fatty Acids, Unsaturated; Hydrazines; Lung; Meclofenamic Acid; Phenylisopropyladenosine; Purinergic Antagonists; Receptors, Prostaglandin; Receptors, Purinergic; Receptors, Thromboxane; Thromboxane A2; Vasoconstriction; Vasodilator Agents; Xanthines

1991
Redistribution of cellular energy following renal ischemia.
    Pediatric nephrology (Berlin, Germany), 1991, Volume: 5, Issue:5

    Topics: Acute Kidney Injury; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Energy Metabolism; In Vitro Techniques; Ischemia; Kidney; Kidney Tubules; Microscopy, Electron; Oxygen Consumption; Perfusion; Rats; Rats, Inbred Strains; Tissue Distribution

1991
P2 purinoceptor agonists stimulate somatostatin secretion from dog pancreas.
    European journal of pharmacology, 1990, Jul-03, Volume: 182, Issue:2

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Anesthesia; Animals; Dogs; Glucagon; In Vitro Techniques; Insulin; Insulin Secretion; Pancreas; Receptors, Purinergic; Somatostatin; Thionucleotides

1990
Isolation and characterization of 5'-nucleotidase of a human pancreatic tumor cell line.
    Biochimica et biophysica acta, 1991, Jan-29, Volume: 1076, Issue:2

    Topics: 5'-Nucleotidase; Adenosine Diphosphate; Antigen-Antibody Complex; Cell Line; Chromatography, Affinity; Concanavalin A; Electrophoresis, Polyacrylamide Gel; Fluorescent Antibody Technique; Humans; Kinetics; Molecular Weight; Pancreatic Neoplasms

1991
Endothelium-dependent hyperpolarization elicited by adenine compounds in rabbit carotid artery.
    The American journal of physiology, 1991, Volume: 260, Issue:4 Pt 2

    Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Calcium; Carotid Arteries; Cell Membrane; Electrophysiology; Endothelium, Vascular; Kinetics; Male; Membrane Potentials; Rabbits

1991
Pathways of purine metabolism in human adipocytes. Further evidence against a role of adenosine as an endogenous regulator of human fat cell function.
    The Journal of biological chemistry, 1990, Jan-05, Volume: 265, Issue:1

    Topics: Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Kinase; Adenosine Monophosphate; Adenosine Triphosphate; Adipose Tissue; Glycerophosphates; Humans; Hypoxanthine; Hypoxanthines; Inosine; Inosine Monophosphate; Isoproterenol; Lipolysis; Pentostatin; Purines; Tubercidin

1990
A new method of sampling blood for measurement of plasma adenosine.
    The American journal of physiology, 1990, Volume: 258, Issue:4 Pt 2

    Topics: Adenine; Adenosine; Adenosine Diphosphate; Blood Specimen Collection; Carbon Radioisotopes; Catheterization; Dipyridamole; Humans

1990
Structural comparison of the 68 kDa laminin-binding protein and 5'-nucleotidase from chicken muscular sources: evidence against a gross structural similarity of both proteins.
    Biochimica et biophysica acta, 1989, Feb-23, Volume: 994, Issue:3

    Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Antibody Specificity; Blotting, Western; Chickens; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Epitopes; Gizzard, Avian; Glycoside Hydrolases; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Molecular Structure; Molecular Weight; Muscles; Nucleotidases; Receptors, Immunologic; Receptors, Laminin

1989
Protection of the kidney against ischemic injury by inhibition of 5'-nucleotidase.
    The American journal of physiology, 1989, Volume: 256, Issue:2 Pt 2

    Topics: 5'-Nucleotidase; Adenosine Diphosphate; Animals; Hypoxanthine; Hypoxanthines; Ischemia; Kidney; Kinetics; Male; Nucleotidases; Rats; Rats, Inbred Strains; Renal Circulation

1989
Turnover of adenosine in plasma of human and dog blood.
    The American journal of physiology, 1989, Volume: 256, Issue:4 Pt 1

    Topics: 5'-Nucleotidase; Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosylhomocysteinase; Animals; Blood Flow Velocity; Dipyridamole; Dogs; Forearm; Half-Life; Humans; Hydrolases; Nucleotidases; Tritium

1989
Purification and properties of a 5'-nucleotidase from rat renal membranes.
    Enzyme, 1989, Volume: 41, Issue:2

    Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cations, Divalent; Cell Membrane; Concanavalin A; Detergents; Hydrogen-Ion Concentration; In Vitro Techniques; Kidney; Nucleotidases; Rats

1989
Production of AMP and adenosine in the interstitial fluid compartment of the isolated perfused normoxic guinea pig heart.
    Pflugers Archiv : European journal of physiology, 1989, Volume: 414, Issue:4

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Extracellular Space; Guinea Pigs; Heart; Hydroxydopamines; Inosine; Male; Myocardium; Oxidopamine; Pyrophosphatases; Sympathectomy, Chemical

1989
Differential effects of purinergic and cholinergic activation on the hydrolysis of membrane polyphosphoinositides in rat pancreatic islets.
    Biochemical pharmacology, 1988, Apr-01, Volume: 37, Issue:7

    Topics: Adenosine Diphosphate; Animals; Calcium; Carbachol; Hydrolysis; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Phosphatidylinositols; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Receptors, Purinergic

1988
The generation of alloreactive cytotoxic T lymphocytes requires the expression of ecto-5'nucleotidase activity.
    Journal of immunology (Baltimore, Md. : 1950), 1988, Dec-01, Volume: 141, Issue:11

    Topics: 5'-Nucleotidase; Adenosine Diphosphate; Humans; Hypoxanthine; Hypoxanthines; Immune Sera; Immunity, Innate; Immunosuppressive Agents; Kinetics; Lymphocyte Activation; Nucleotidases; Stem Cells; T-Lymphocytes, Cytotoxic

1988
Intracellular adenosine formation and its carrier-mediated release in cultured embryonic chick heart cells.
    Life sciences, 1988, Volume: 43, Issue:23

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Biological Transport; Carrier Proteins; Cells, Cultured; Chick Embryo; Deoxyglucose; Dilazep; Dipyridamole; Heart; Hexobendine; Membrane Proteins; Myocardium; Nucleoside Transport Proteins; Nucleotidases; Nucleotides; Oligomycins; Oxygen

1988
Inhibition of adenosine-metabolizing enzymes modulates mouse sperm fertilizing ability: a changing role for endogenously generated adenosine during capacitation.
    Gamete research, 1988, Volume: 21, Issue:3

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Coformycin; Fertilization; Fertilization in Vitro; Male; Mice; Nucleotidases; Sperm Capacitation

1988
Direct assay method for inosine 5'-monophosphate dehydrogenase activity.
    Analytical biochemistry, 1985, Volume: 150, Issue:1

    Topics: Adenosine Diphosphate; Allopurinol; Animals; Edetic Acid; Electrophoresis; IMP Dehydrogenase; Ketone Oxidoreductases; Liver; Liver Neoplasms, Experimental; Male; Rats; Rats, Inbred ACI

1985
Evidence that ATP is a neurotransmitter in the frog heart.
    European journal of pharmacology, 1986, May-27, Volume: 124, Issue:3

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Atropine; Electric Stimulation; Epinephrine; Heart; In Vitro Techniques; Male; Neurotransmitter Agents; Propranolol; Rana temporaria

1986
[Potentiating synergism between alpha, beta-methylene ADP and acetylcholine on the secretion of insulin from the isolated pancreas of the newborn dog].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1987, Volume: 181, Issue:1

    Topics: Acetylcholine; Adenosine Diphosphate; Animals; Dogs; Drug Synergism; Insulin; Insulin Secretion

1987
5'-Nucleotidase from rat heart membranes. Inhibition by adenine nucleotides and related compounds.
    The Biochemical journal, 1985, Mar-15, Volume: 226, Issue:3

    Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cell Membrane; Hydrogen-Ion Concentration; Kinetics; Magnesium; Myocardium; Nucleotidases; Rats

1985
Apamin distinguishes two types of relaxation mediated by enteric nerves in the guinea-pig gastrointestinal tract.
    Naunyn-Schmiedeberg's archives of pharmacology, 1986, Volume: 332, Issue:1

    Topics: Adenosine Diphosphate; Animals; Apamin; Bee Venoms; Colon; Digestive System; Dogs; Female; Ileum; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Papaverine; Stomach; Synaptic Transmission; Vasoactive Intestinal Peptide

1986
The inhibition of rat adipocyte ecto-5'-nucleotidase by xanthines is not related to lipolysis.
    Biochemical pharmacology, 1986, Mar-01, Volume: 35, Issue:5

    Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adipose Tissue; Animals; Lipid Mobilization; Male; Nucleotidases; Rats; Structure-Activity Relationship; Theophylline; Xanthines

1986
Adenosine production and release by adult rat cardiocytes.
    Journal of molecular and cellular cardiology, 1986, Volume: 18, Issue:6

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Biological Transport, Active; Dinitrophenols; Dipyridamole; Heart; In Vitro Techniques; Iodoacetates; Iodoacetic Acid; Myocardium; Nucleotidases; Rats; Rats, Inbred Strains; Thioinosine

1986
Separate mechanisms for cellular uptake of purine nucleotides by B- and T-lymphoblasts.
    Advances in experimental medicine and biology, 1986, Volume: 195 Pt B

    Topics: 5'-Nucleotidase; Adenosine Diphosphate; B-Lymphocytes; Biological Transport; Cell Line; Humans; Nucleotidases; Phosphoric Monoester Hydrolases; Purine Nucleotides; Purines; T-Lymphocytes

1986
The influence of inhibitors of the ATP degradative pathway on recovery of function and high energy phosphate after transient ischemia in the rat heart.
    Journal of molecular and cellular cardiology, 1986, Volume: 18 Suppl 4

    Topics: 5'-Nucleotidase; Acute Disease; Adenine; Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Triphosphate; Adenylate Kinase; Animals; Coronary Circulation; Coronary Disease; Dinucleoside Phosphates; Male; Nucleotidases; Rats; Rats, Inbred Strains; Thioinosine

1986
The effect of reserpine on sympathetic, purinergic neurotransmission in the isolated mesenteric artery of the dog: a pharmacological study.
    British journal of pharmacology, 1987, Volume: 91, Issue:3

    Topics: Adenosine Diphosphate; Animals; Dogs; Electric Stimulation; Female; In Vitro Techniques; Male; Mesenteric Arteries; Neuropeptides; Potassium Chloride; Prazosin; Receptors, Purinergic; Reserpine; Sympathetic Nervous System; Synaptic Transmission; Theophylline; Tyramine

1987
Suramin: a reversible P2-purinoceptor antagonist in the mouse vas deferens.
    British journal of pharmacology, 1988, Volume: 93, Issue:2

    Topics: Adenosine Diphosphate; Animals; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Muscle Contraction; Muscle, Smooth; Receptors, Purinergic; Suramin

1988
Adenosine diphosphate potentiates the inhibition of norepinephrine-induced relaxation by 5-hydroxytryptamine in canine coronary arteries.
    European journal of pharmacology, 1987, Jan-20, Volume: 133, Issue:3

    Topics: 5-Hydroxytryptophan; Adenosine Diphosphate; Animals; Coronary Vessels; Dogs; Drug Interactions; In Vitro Techniques; Methiothepin; Muscle, Smooth, Vascular; Norepinephrine; Prazosin

1987
Potentiating synergism between adenosine diphosphate or triphosphate and acetylcholine on insulin secretion.
    The American journal of physiology, 1986, Volume: 251, Issue:4 Pt 1

    Topics: Acetylcholine; Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Drug Synergism; In Vitro Techniques; Insulin; Insulin Secretion; Male; Pancreas; Rats; Rats, Inbred Strains

1986
ATP and phosphate-modified adenine nucleotide analogues. Effects on insulin secretion and calcium uptake.
    Biochemical pharmacology, 1987, Feb-01, Volume: 36, Issue:3

    Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Insulin; Insulin Secretion; Islets of Langerhans; Male; Phosphates; Rats; Rats, Inbred Strains; Verapamil

1987
[3-Phosphono-2-imino-4-oxoimidazoline--a competitive substrate of AMP-dephosphorylating enzymes from the cytosol fraction of the rat heart].
    Biokhimiia (Moscow, Russia), 1987, Volume: 52, Issue:4

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Animals; Binding, Competitive; Catalysis; Cytosol; Hydrolysis; Imidazolidines; In Vitro Techniques; Kinetics; Myocardium; Nitrophenols; Organophosphorus Compounds; Phosphocreatine; Rats; Substrate Specificity

1987
Autonomic innervation of the canine penile artery and vein in relation to neural mechanisms involved in erection.
    British journal of urology, 1987, Volume: 59, Issue:5

    Topics: Adenosine Diphosphate; Animals; Autonomic Agents; Dogs; Electric Stimulation; Male; Membrane Potentials; Muscle Contraction; Muscle Relaxation; Penile Erection; Penis; Vasoactive Intestinal Peptide; Vasomotor System

1987
An assessment of the antagonistic activity of reactive blue 2 at P1- and P2-purinoceptors: supporting evidence for purinergic innervation of the rabbit portal vein.
    European journal of pharmacology, 1987, Aug-04, Volume: 140, Issue:1

    Topics: Adenosine Diphosphate; Animals; Electric Stimulation; Ergotamine; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Portal Vein; Rabbits; Rats; Rats, Inbred Strains; Receptors, Purinergic; Species Specificity; Triazines

1987
Release of endogenous and radioactive purines from the rabbit retina.
    Brain research, 1986, Nov-19, Volume: 398, Issue:1

    Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Animals; Dipyridamole; Evoked Potentials; Female; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Male; Potassium; Purines; Rabbits; Retina; Tritium

1986
Adenosine release into venous plasma during free flow exercise.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1986, Volume: 181, Issue:3

    Topics: Adenosine; Adenosine Diphosphate; Animals; Chromatography, High Pressure Liquid; Dogs; Electric Stimulation; Isoproterenol; Male; Oxygen Consumption; Physical Exertion; Veins

1986
The mechanism of adenosine release from hypoxic rat liver cells.
    British journal of pharmacology, 1985, Volume: 85, Issue:2

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Dipyridamole; Liver; Oxygen; Rats; Thioinosine

1985
Purine-mediated relaxation and constriction of isolated rabbit mesenteric artery are not endothelium-dependent.
    European journal of pharmacology, 1985, Dec-03, Volume: 118, Issue:3

    Topics: Acetylcholine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Endothelium; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle Relaxation; Muscle Tonus; Muscle, Smooth, Vascular; Purines; Rabbits

1985
Kinetic properties of 5' nucleotidase in blood lymphocytes from healthy subjects, immunodeficient patients and cord blood.
    Clinical and experimental immunology, 1984, Volume: 57, Issue:1

    Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adult; Agammaglobulinemia; Aged; Cell Membrane; Fetal Blood; Humans; Kinetics; Leukemia, Lymphoid; Lymphocytes; Middle Aged; Nucleotidases; Zinc

1984
Effects of adenosine, adenosine triphosphate and structural analogues on glucagon secretion from the perfused pancreas of rat in vitro.
    British journal of pharmacology, 1984, Volume: 83, Issue:4

    Topics: 2-Chloroadenosine; 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Glucagon; In Vitro Techniques; Male; Nucleotidases; Pancreas; Rats; Theophylline

1984
Adenosine receptors mediating cyclic AMP production in the rat hippocampus.
    Journal of neurochemistry, 1982, Volume: 39, Issue:1

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adrenergic Agonists; Animals; Cyclic AMP; Guanosine Monophosphate; Hippocampus; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic

1982
Interaction of a methylene diphosphonate analog of ADP with photosynthetic membranes of chloroplasts.
    Biochemical and biophysical research communications, 1980, Nov-17, Volume: 97, Issue:1

    Topics: Adenosine Diphosphate; Chloroplasts; Intracellular Membranes; Kinetics; Light; Nucleoside-Diphosphate Kinase; Photophosphorylation; Plants; Proton-Translocating ATPases

1980
Plasma membrane enzymes in BALB/c lymphomas with either T or B cell properties, I. 5'-Nucleotidase.
    Journal of receptor research, 1981, Volume: 2, Issue:1

    Topics: 5'-Nucleotidase; Abelson murine leukemia virus; Adenosine Diphosphate; Animals; B-Lymphocytes; Cell Membrane; Cell Transformation, Viral; Hydrogen-Ion Concentration; Lymphoma; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Nucleotidases; Plasmacytoma; Spleen; Substrate Specificity; T-Lymphocytes; Thymoma

1981
Regulation of purine metabolism by plasma membrane and cytoplasmic 5'-nucleotidases.
    The American journal of physiology, 1982, Volume: 243, Issue:5

    Topics: 5'-Nucleotidase; Adenosine Diphosphate; B-Lymphocytes; Cell Line; Cell Membrane; Cytoplasm; Dipyridamole; Humans; Kinetics; Leukemia, Lymphoid; Lymphocytes; Nucleotidases; Purine Nucleotides; Purines; Substrate Specificity; T-Lymphocytes; Thymus Gland

1982
Delineation of membrane-bound phosphatase activities in normal and leukemic thymocytes.
    Biochimica et biophysica acta, 1983, Apr-20, Volume: 756, Issue:3

    Topics: 5'-Nucleotidase; Adenosine Diphosphate; Animals; Cell Membrane; Leukemia, Experimental; Mice; Mice, Inbred AKR; Nitrophenols; Nucleotidases; Organophosphorus Compounds; Phosphoric Monoester Hydrolases; T-Lymphocytes; Tetramisole

1983
Release of adenosine, inosine and hypoxanthine from rabbit non-myelinated nerve fibres at rest and during activity.
    The Journal of physiology, 1984, Volume: 357

    Topics: Action Potentials; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antimetabolites; Cyanides; Deoxyglucose; Glucose; Hydrolysis; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Nerve Fibers; Rabbits

1984
Adenosine as a mediator of postcontraction hyperemia in dog gracilis muscle.
    The American journal of physiology, 1984, Volume: 246, Issue:2 Pt 2

    Topics: Adenine; Adenosine; Adenosine Diphosphate; Animals; Dipyridamole; Dogs; Electric Conductivity; Female; Male; Muscle Contraction; Muscles; Oxygen Consumption; Perfusion

1984
The alpha beta-methylene analogues of ADP and ATP act as substrates for creatine kinase. delta G0 for this reaction and for the hydrolysis of the alpha beta-methylene analogue of ATP.
    European journal of biochemistry, 1983, Jun-01, Volume: 133, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Creatine Kinase; Hydrolysis; Kinetics; Magnetic Resonance Spectroscopy; Muscles; Rabbits; Substrate Specificity

1983
31P nuclear magnetic resonance of phosphonic acid analogues of adenosine nucleotides as functions of pH and magnesium ion concentration.
    Biochemistry, 1982, Jan-19, Volume: 21, Issue:2

    Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Hydrogen-Ion Concentration; Magnesium; Magnetic Resonance Spectroscopy; Molecular Conformation; Organophosphonates

1982
Actions of adenine dinucleotides on the vas deferens, guinea-pig taenia caeci and bladder.
    European journal of pharmacology, 1981, Oct-22, Volume: 75, Issue:2-3

    Topics: Adenine Nucleotides; Adenosine Diphosphate; Animals; Cecum; Dinucleoside Phosphates; Guinea Pigs; In Vitro Techniques; Male; Mice; Muscle Contraction; NAD; NADP; Rats; Rats, Inbred Strains; Urinary Bladder; Vas Deferens

1981
5'-nucleotidase activates and an inhibitory antibody prevents neuritic differentiation of PC12 cells.
    The European journal of neuroscience, 1995, Jun-01, Volume: 7, Issue:6

    Topics: 5'-Nucleotidase; Adenosine Diphosphate; Animals; Antibodies; Cell Differentiation; Neural Inhibition; Neurites; PC12 Cells; Rats; Time Factors

1995
Does interstitial adenosine mediate acute hibernation of guinea pig myocardium?
    Cardiovascular research, 1995, Volume: 29, Issue:6

    Topics: 5'-Nucleotidase; Acute Disease; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cytosol; Guinea Pigs; Heart; Inosine; Lactates; Lactic Acid; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Stunning; Myocardium; Phosphorylation; Theophylline

1995
P2-purinoceptor-mediated inhibition of noradrenaline release in rat atria.
    British journal of pharmacology, 1995, Volume: 115, Issue:2

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antihypertensive Agents; Atropine; Desipramine; Dose-Response Relationship, Drug; Electric Stimulation; Heart Atria; Indomethacin; Male; Norepinephrine; Phenethylamines; Protein Synthesis Inhibitors; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Suramin; Triazines; Xanthines; Yohimbine

1995
Alpha 1-adrenoceptor activation increases ecto-5'-nucleotidase activity and adenosine release in rat cardiomyocytes by activating protein kinase C.
    Circulation, 1995, Apr-15, Volume: 91, Issue:8

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; In Vitro Techniques; Indoles; Male; Maleimides; Methoxamine; Myocardium; Norepinephrine; Protein Kinase C; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Tetradecanoylphorbol Acetate

1995
Contribution of endothelium and cardiomyocytes to hypoxia-induced adenosine release.
    Journal of molecular and cellular cardiology, 1994, Volume: 26, Issue:8

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Cell Hypoxia; Coronary Circulation; Coronary Vessels; Endothelium, Vascular; Energy Metabolism; Heart; Male; Muscle Proteins; Myocardium; Perfusion; Rats; Rats, Sprague-Dawley; Uric Acid; Vasodilation

1994
ATP released together with acetylcholine as the mediator of neuromuscular depression at frog motor nerve endings.
    The Journal of physiology, 1994, May-15, Volume: 477, Issue:Pt 1

    Topics: Acetylcholine; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Electric Stimulation; Motor Endplate; Motor Neurons; Neuromuscular Junction; Purinergic P1 Receptor Antagonists; Rana pipiens; Receptors, Presynaptic; Receptors, Purinergic P1; Synaptic Transmission

1994
Infarct size-limiting effect of ischemic preconditioning is blunted by inhibition of 5'-nucleotidase activity and attenuation of adenosine release.
    Circulation, 1994, Volume: 89, Issue:3

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Dogs; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Time Factors

1994
5'-Nucleotidase inhibition enhances postischemic myocardial performance.
    The Journal of surgical research, 1994, Volume: 56, Issue:4

    Topics: 5'-Nucleotidase; Adenosine Diphosphate; Animals; Cardioplegic Solutions; Crystalloid Solutions; Dogs; Heart; Hemodynamics; Isotonic Solutions; Myocardial Ischemia; Myocardial Reperfusion; Plasma Substitutes; Ventricular Function, Left

1994
Characteristics of membrane-bound 5'-nucleotidase on human prostasomes.
    Clinica chimica acta; international journal of clinical chemistry, 1993, Jul-16, Volume: 216, Issue:1-2

    Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adult; Concanavalin A; Humans; In Vitro Techniques; Kinetics; Levamisole; Male; Nucleotidases; Octoxynol; Organelles; Phosphoric Monoester Hydrolases; Semen; Tartrates

1993
Activated eosinophils evoke chloride secretion in model intestinal epithelia primarily via regulated release of 5'-AMP.
    Journal of immunology (Baltimore, Md. : 1950), 1993, Nov-15, Volume: 151, Issue:10

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adult; Cell Line; Cells, Cultured; Chlorides; Eosinophils; Epithelium; Humans; Intestinal Mucosa; Theophylline

1993
Evaluation of the effectiveness of 5'-nucleotidase inhibitor and allopurinol in myocardial ischemia.
    Japanese circulation journal, 1993, Volume: 57, Issue:8

    Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Allopurinol; Animals; Coronary Circulation; In Vitro Techniques; Male; Myocardial Ischemia; Myocardium; Purines; Rats; Rats, Inbred Lew; Vascular Resistance; Ventricular Function, Left; Xanthine Oxidase

1993
Intracellular formation and release of adenosine from rat hippocampal slices evoked by electrical stimulation or energy depletion.
    Neurochemistry international, 1993, Volume: 23, Issue:2

    Topics: Adenosine; Adenosine Diphosphate; Animals; Electric Stimulation; Energy Metabolism; Hippocampus; Homocysteine; In Vitro Techniques; Intracellular Membranes; Male; Purines; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine

1993
Manipulation of endogenous adenosine in the rat prepiriform cortex modulates seizure susceptibility.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 264, Issue:3

    Topics: Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Kinase; Animals; Bicuculline; Cerebral Cortex; Male; Pentostatin; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Seizures; Theophylline; Thioinosine

1993
Evidence that [3H]-alpha,beta-methylene ATP may label an endothelial-derived cell line 5'-nucleotidase with high affinity.
    British journal of pharmacology, 1995, Volume: 115, Issue:5

    Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Binding, Competitive; Cell Line; Cell Membrane; Endothelium, Vascular; Guanosine Monophosphate; Kinetics; Rats; Rats, Wistar; Receptors, Purinergic P2

1995
Release of oxygen metabolites from chemoattractant-stimulated neutrophils is inhibited by resting platelets: role of extracellular adenosine and actin polymerization.
    Blood, 1996, May-15, Volume: 87, Issue:10

    Topics: Actin Cytoskeleton; Actins; Adenine; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Biological Factors; Blood Platelets; Cells, Cultured; Chemotactic Factors; Chemotaxis, Leukocyte; Culture Media, Conditioned; Cytochalasin B; Humans; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Purinergic P1 Receptor Antagonists; Reactive Oxygen Species; Receptors, Purinergic P1; Respiratory Burst; Theophylline

1996
Endo 5'-nucleotidase in healthy peripheral blood lymphocytes. Inhibition by alpha beta methylene adenosine 5'-diphosphate.
    Biochemical Society transactions, 1996, Volume: 24, Issue:1

    Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Monophosphate; B-Lymphocytes; Cytosol; Enzyme Inhibitors; Humans; Inosine Monophosphate; Isoenzymes; Lymphocytes; Reference Values; Substrate Specificity; T-Lymphocytes

1996
Regulation of proliferation of LLC-MK2 cells by nucleosides and nucleotides: the role of ecto-enzymes.
    The Biochemical journal, 1996, Jun-01, Volume: 316 ( Pt 2)

    Topics: 5'-Nucleotidase; Acid Anhydride Hydrolases; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Alkaline Phosphatase; Animals; Cell Division; Cell Line; Cell Line, Transformed; Dinucleoside Phosphates; Dipyridamole; Enzyme Inhibitors; HeLa Cells; Humans; Levamisole; Nucleoside-Triphosphatase; Nucleosides; Nucleotides; Suramin; Thymidine; Triazines

1996
Cardioprotection due to preconditioning correlates with increased ecto-5'-nucleotidase activity.
    The American journal of physiology, 1996, Volume: 270, Issue:1 Pt 2

    Topics: 5'-Nucleotidase; Adenosine Diphosphate; Animals; Cytosol; Dogs; Female; Hemodynamics; Male; Myocardial Infarction; Myocardial Ischemia; Recurrence; Time Factors

1996
Preferential release of ATP and its extracellular catabolism as a source of adenosine upon high- but not low-frequency stimulation of rat hippocampal slices.
    Journal of neurochemistry, 1996, Volume: 67, Issue:5

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Electric Stimulation; Energy Metabolism; Enzyme Inhibitors; Hippocampus; In Vitro Techniques; Kinetics; Long-Term Potentiation; Male; Models, Neurological; Neurons; Rats; Rats, Wistar; Time Factors; Tritium

1996
Studies on the roles of ATP, adenosine and nitric oxide in mediating muscle vasodilatation induced in the rat by acute systemic hypoxia.
    The Journal of physiology, 1996, Sep-01, Volume: 495 ( Pt 2)

    Topics: 5'-Nucleotidase; Acute Disease; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Enzyme Inhibitors; Hypoxia; Male; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxygen Consumption; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Regional Blood Flow; Theophylline; Vasodilation

1996
Activation of ecto-5'-nucleotidase by protein kinase C attenuates irreversible cellular injury due to hypoxia and reoxygenation in rat cardiomyocytes.
    Journal of molecular and cellular cardiology, 1996, Volume: 28, Issue:9

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Cell Hypoxia; Cell Survival; Enzyme Activation; In Vitro Techniques; Male; Methoxamine; Myocardium; Oxygen; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate

1996
Evidence for the involvement of ecto-5'-nucleotidase (CD73) in drug resistance.
    International journal of cancer, 1996, Nov-15, Volume: 68, Issue:4

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Doxorubicin; Drug Resistance, Multiple; Humans; Mice; Rhodamines; RNA, Messenger; Tumor Cells, Cultured

1996
Soluble forms of 5'-nucleotidase in rat and human heart.
    The American journal of physiology, 1996, Volume: 270, Issue:4 Pt 2

    Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cytosol; Heart Ventricles; Humans; Isoenzymes; Myocardium; Rats; Solubility

1996
A source of adenosine involved in cardiovascular responses to defense area stimulation.
    The American journal of physiology, 1997, Volume: 272, Issue:1 Pt 2

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Cardiovascular System; Defense Mechanisms; Electric Stimulation; Enzyme Inhibitors; Femoral Artery; Heart Rate; Male; Medulla Oblongata; Microinjections; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Solitary Nucleus

1997
Vesnarinone limits infarct size via adenosine-dependent mechanisms in the canine heart.
    Circulation, 1997, Apr-15, Volume: 95, Issue:8

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Cardiotonic Agents; Dipyridamole; Dogs; Enzyme Activation; Enzyme Inhibitors; Infusions, Intra-Arterial; Ion Channel Gating; Myocardial Infarction; Myocardial Reperfusion Injury; Potassium Channels; Pyrazines; Quinolines; Receptors, Purinergic P1; Theophylline

1997
P2-receptor-mediated inhibition of noradrenaline release in the rat hippocampus.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 355, Issue:6

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Electric Stimulation; Hippocampus; In Vitro Techniques; Isotope Labeling; Male; Norepinephrine; Phenethylamines; Rats; Rats, Wistar; Receptors, Purinergic P2; Thionucleotides; Triazines; Tritium; Xanthines; Yohimbine

1997
Evidence against a major role of adenosine in oxygen-dependent regulation of erythropoietin in rats.
    Kidney international, 1997, Volume: 52, Issue:2

    Topics: Adenine; Adenosine; Adenosine Diphosphate; Animals; Antihypertensive Agents; Carbon Monoxide; Dipyridamole; Diuretics; Drug Synergism; Enzyme Inhibitors; Erythropoietin; Gene Expression; Hypoxia; Kidney; Male; Oxygen; Phenethylamines; Phosphodiesterase Inhibitors; Piperazines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; RNA, Messenger; Theophylline; Vasodilator Agents; Xanthines

1997
Adenosine triphosphate degradation products after oxidative stress and metabolic dysfunction in cultured retinal cells.
    Journal of neurochemistry, 1997, Volume: 69, Issue:3

    Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Cell Hypoxia; Cells, Cultured; Chick Embryo; Enzyme Inhibitors; Glucose; Hypoxanthine; Inosine; Iodoacetates; Iodoacetic Acid; Ischemia; Kinetics; Oligomycins; Oxidative Stress; Retina; Thioinosine

1997
Stimulation of alpha 1-adrenoceptors and protein kinase C-mediated activation of ecto-5'-nucleotidase in rat hearts in vivo.
    The Journal of physiology, 1997, Aug-15, Volume: 503 ( Pt 1)

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Alkaloids; Analysis of Variance; Animals; Benzophenanthridines; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Female; Heart; Kinetics; Male; Methoxamine; Microdialysis; Myocardium; Norepinephrine; Perfusion; Phenanthridines; Prazosin; Protein Kinase C; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1

1997
Types of potassium channels involved in coronary reactive hyperemia depend on duration of preceding ischemia in rat hearts.
    Life sciences, 1997, Volume: 61, Issue:10

    Topics: 4-Aminopyridine; Adenosine Diphosphate; Animals; Apamin; Charybdotoxin; Glyburide; Hyperemia; In Vitro Techniques; Indomethacin; Male; Myocardial Ischemia; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Potassium Channels; Rats; Rats, Wistar; Regional Blood Flow; Tetraethylammonium; Tetraethylammonium Compounds

1997
Structure-based analysis of catalysis and substrate definition in the HIT protein family.
    Science (New York, N.Y.), 1997, Oct-10, Volume: 278, Issue:5336

    Topics: Acid Anhydride Hydrolases; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Binding Sites; Catalysis; Crystallography, X-Ray; Dimerization; Dinucleoside Phosphates; Hydrogen Bonding; Neoplasm Proteins; Nerve Tissue Proteins; Protein Structure, Secondary; Proteins; Structure-Activity Relationship; Substrate Specificity; Tungsten Compounds

1997
The signalling pathway which causes contraction via P2-purinoceptors in rat urinary bladder smooth muscle.
    British journal of pharmacology, 1997, Volume: 122, Issue:3

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Carbamates; Estrenes; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Phenylcarbamates; Potassium Chloride; Pyrrolidinones; Rats; Rats, Wistar; Receptors, Purinergic P2; Signal Transduction; Thionucleotides; Urinary Bladder

1997
The role of cyclic AMP as a precursor of extracellular adenosine in the rat hippocampus.
    Neuropharmacology, 1997, Volume: 36, Issue:9

    Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Animals; Colforsin; Cyclic AMP; Diterpenes; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Guanosine Monophosphate; Hippocampus; In Vitro Techniques; Male; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theophylline

1997
Ecto-5'-nucleotidase mediates infarct size-limiting effect by ischemic preconditioning in the rabbit heart.
    Journal of cardiovascular pharmacology, 1997, Volume: 30, Issue:6

    Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Enzyme Inhibitors; Hemodynamics; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Rabbits

1997
Source of extracellular brain adenosine during hypoxia in fetal sheep.
    Brain research, 1997, Dec-19, Volume: 778, Issue:2

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Animals; Cerebrospinal Fluid; Enzyme Inhibitors; Female; Fetal Hypoxia; Microdialysis; Pregnancy; Respiration; Sheep; Thalamus

1997
Effects of ischemic preconditioning on contractile and metabolic function during hypoperfusion in dogs.
    The American journal of physiology, 1998, Volume: 274, Issue:2

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Blood Flow Velocity; Coronary Circulation; Coronary Vessels; Dogs; Enzyme Inhibitors; Hydrogen-Ion Concentration; Ischemic Preconditioning, Myocardial; Lactic Acid; Myocardial Contraction; Myocardium; Purinergic P1 Receptor Antagonists; Theophylline

1998
Neutrophil 5-nucleotidase reaction in chronic myelogenous leukemia, myelofibrosis with myeloid metaplasia, and polycythemia vera.
    Annals of hematology, 1998, Volume: 76, Issue:1

    Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adjuvants, Immunologic; Alkaline Phosphatase; Enzyme Inhibitors; Homoarginine; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Levamisole; Neutrophils; Phenylalanine; Polycythemia Vera; Primary Myelofibrosis

1998
Ecto-5'-nucleotidase is not required for ischemic preconditioning in rabbit myocardium in situ.
    The American journal of physiology, 1998, Volume: 275, Issue:4

    Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Blood Pressure; Enzyme Inhibitors; Heart; Heart Rate; Ischemic Preconditioning; Male; Myocardial Contraction; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Purinergic P1 Receptor Antagonists; Rabbits; Theophylline

1998
Evidence that P2X purinoceptors mediate the excitatory effects of alphabetamethylene-ADP in rat locus coeruleus neurones.
    Neuropharmacology, 1998, Volume: 37, Issue:7

    Topics: Adenosine Diphosphate; Animals; Enzyme Inhibitors; Locus Coeruleus; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Purinergic P2 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Spinal Nerve Roots; Thionucleotides; Vagus Nerve

1998
Stimulation of large-conductance Ca2+-activated K+ channels by Evans blue in cultured endothelial cells of human umbilical veins.
    Biochemical and biophysical research communications, 1999, Jan-27, Volume: 254, Issue:3

    Topics: Adenosine Diphosphate; Capillary Permeability; Cells, Cultured; Endothelium, Vascular; Evans Blue; Humans; Kinetics; Large-Conductance Calcium-Activated Potassium Channels; Membrane Potentials; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Calcium-Activated; Suramin; Umbilical Veins

1999
P2 purinoceptors contribute to ATP-induced inhibition of L-type Ca2+ current in rabbit atrial myocytes.
    Cardiovascular research, 1999, Volume: 41, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; 5'-Nucleotidase; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Calcium-Transporting ATPases; Colforsin; Cyclic AMP; Enzyme Inhibitors; Isoproterenol; Myocardium; Patch-Clamp Techniques; Pertussis Toxin; Potassium Channels; Potassium Channels, Voltage-Gated; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rabbits; Receptors, Purinergic P2; Shal Potassium Channels; Suramin; Virulence Factors, Bordetella; Xanthines

1999
Immunologically distinct isoforms of ecto-5'-nucleotidase in nerve terminals of different areas of the rat hippocampus.
    Journal of neurochemistry, 2000, Volume: 74, Issue:1

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Extracellular Space; Hippocampus; Immune Sera; Immunologic Techniques; Isoenzymes; Kinetics; Nerve Endings; Rabbits; Rats; Synaptosomes; Tissue Distribution

2000
Neural mechanisms of impaired micturition reflex in rats with acute partial bladder outlet obstruction.
    Neuroscience, 2000, Volume: 96, Issue:1

    Topics: Acute Disease; Adenosine Diphosphate; Animals; Atropine; Drug Combinations; Electromyography; Female; Muscarinic Antagonists; Nervous System; Neurons, Afferent; Neurons, Efferent; Nicotinic Antagonists; Pelvis; Rats; Rats, Wistar; Reflex; Tubocurarine; Urethra; Urinary Bladder; Urinary Bladder Neck Obstruction; Urination

2000
Reserpine attenuates interstitial adenosine-mediated activation of ecto-5'-nucleotidase in rat hearts in vivo.
    Archives of biochemistry and biophysics, 2000, Mar-15, Volume: 375, Issue:2

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adrenergic Uptake Inhibitors; Animals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Activation; Heart; Male; Microdialysis; Myocardium; Norepinephrine; Perfusion; Phosphorylation; Rats; Rats, Wistar; Reserpine; Stellate Ganglion; Tyramine

2000
Complex hippocampal responses to ATP: fade due to nucleotidase inhibition and P2-receptor-mediated adenosine release.
    Brain research, 2000, Mar-31, Volume: 860, Issue:1-2

    Topics: 5'-Nucleotidase; Action Potentials; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Enzyme Inhibitors; Hippocampus; Male; Nerve Tissue Proteins; Rats; Rats, Wistar; Receptors, Purinergic P2; Suramin; Theophylline

2000
Structural basis for the function of Bacillus subtilis phosphoribosyl-pyrophosphate synthetase.
    Nature structural biology, 2000, Volume: 7, Issue:4

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Allosteric Regulation; Allosteric Site; Amino Acid Sequence; Bacillus subtilis; Binding Sites; Catalytic Domain; Crystallization; Crystallography, X-Ray; Enzyme Activation; Models, Molecular; Molecular Sequence Data; Protein Conformation; Ribose-Phosphate Pyrophosphokinase; Sequence Alignment; Structure-Activity Relationship; Sulfates

2000
Ecto-5'-nucleotidase plays a role in the cardioprotective effects of heat shock protein 72 in ischemia-reperfusion injury in rat hearts.
    Cardiovascular research, 2000, Volume: 47, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Analysis of Variance; Animals; Blotting, Western; Enzyme Activation; Enzyme Inhibitors; Gene Expression; Heat-Shock Proteins; HSP72 Heat-Shock Proteins; Male; Myocardial Reperfusion Injury; Perfusion; Rats; Rats, Sprague-Dawley; Transfection

2000
Role of A(2A)-adenosine receptor activation for ATP-mediated coronary vasodilation in guinea-pig isolated heart.
    British journal of pharmacology, 2000, Volume: 130, Issue:5

    Topics: Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Coronary Vessels; Glyburide; Guinea Pigs; NG-Nitroarginine Methyl Ester; Perfusion; Receptors, Purinergic P1; Thionucleotides; Vasodilation

2000
Extracellular ATP reduces optically monitored electrical signals in hippocampal slices through metabolism to adenosine.
    European journal of pharmacology, 2000, Jul-07, Volume: 399, Issue:2-3

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Electrophysiology; Hippocampus; Organ Culture Techniques; Rats; Rats, Wistar; Signal Transduction; Triazines; Triazoles; Uridine Diphosphate; Xanthines

2000
Correlation between adenine nucleotide-induced cyclic AMP elevation and extracellular adenosine formation in NG108-15 cells.
    Japanese journal of pharmacology, 2000, Volume: 84, Issue:3

    Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cell Membrane; Chromatography, High Pressure Liquid; Cyclic AMP; Enzyme Inhibitors; Extracellular Space; Nucleotidases; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured

2000
Simultaneous assessment of ecto- and cytosolic-5'-nucleotidase activities in brain micropunches.
    Journal of neuroscience methods, 2000, Dec-15, Volume: 104, Issue:1

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Brain; Cell Membrane; Chromatography, High Pressure Liquid; Cytosol; Enzyme Inhibitors; Magnesium; Male; Nucleotidases; Rats; Rats, Sprague-Dawley

2000
Mechanism of hydrolysis of phosphate esters by the dimetal center of 5'-nucleotidase based on crystal structures.
    Journal of molecular biology, 2001, May-25, Volume: 309, Issue:1

    Topics: 5'-Nucleotidase; Acid Phosphatase; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Binding Sites; Catalysis; Conserved Sequence; Crystallography, X-Ray; Escherichia coli; Glycoproteins; Hydrolysis; Ions; Ligands; Metals; Models, Molecular; Phosphates; Phosphoprotein Phosphatases; Protein Binding; Protein Conformation; Rotation; Static Electricity; Structure-Activity Relationship; Substrate Specificity; Temperature; Water

2001
Adenosine linking reduced O2 to arteriolar NO release in intestine is not formed from extracellular ATP.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 281, Issue:3

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Arterioles; Enzyme Inhibitors; Extracellular Space; Intestine, Small; Male; Nitric Oxide; omega-N-Methylarginine; Oxygen; Rats; Rats, Sprague-Dawley; Vascular Patency; Vasoconstriction; Xanthines

2001
Oxidative stress enhances the production and actions of adenosine in the kidney.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2001, Volume: 281, Issue:6

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Catalase; Chromatography, High Pressure Liquid; Cyclic N-Oxides; Dimerization; Ditiocarb; Kidney; Kinetics; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Renal Artery; Spin Labels; Superoxide Dismutase; Superoxides; Thioredoxins; Xanthine; Xanthine Oxidase

2001
Nucleotide-evoked relaxation of rat vas deferens: possible mechanisms.
    European journal of pharmacology, 2002, Feb-01, Volume: 436, Issue:1-2

    Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cyclic AMP; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscle Relaxation; Nucleotides; Potassium; Rats; Rats, Wistar; Theophylline; Thionucleotides; Vas Deferens

2002
Complementary role of extracellular ATP and adenosine in ischemic preconditioning in the rat heart.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 282, Issue:5

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Coloring Agents; Extracellular Space; Ischemic Preconditioning; Male; Microdialysis; Organic Chemicals; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Receptors, Purinergic P2; Suramin; Theophylline; Ventricular Function, Left; Ventricular Pressure

2002
Magnesium reduces myocardial infarct size via enhancement of adenosine mechanism in rabbits.
    Cardiovascular research, 2002, Volume: 54, Issue:3

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Analysis of Variance; Animals; Calcium; Drug Synergism; Enzyme Inhibitors; Magnesium; Male; Models, Animal; Myocardial Infarction; Myocardium; Purinergic P1 Receptor Antagonists; Rabbits; Theophylline

2002
Enzyme kinetics and pharmacological characterization of nucleotidases released from the guinea pig isolated vas deferens during nerve stimulation: evidence for a soluble ecto-nucleoside triphosphate diphosphohydrolase-like ATPase and a soluble ecto-5'-nuc
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 302, Issue:3

    Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Calcium; Chromatography, High Pressure Liquid; Electric Stimulation; Enzyme Inhibitors; Guinea Pigs; In Vitro Techniques; Kinetics; Magnesium; Male; Nucleotidases; Phosphoric Diester Hydrolases; Phosphoric Monoester Hydrolases; Plant Proteins; Pyrophosphatases; Suramin; Sympathetic Nervous System; Vas Deferens

2002
Rapid adenosine release in the nucleus tractus solitarii during defence response in rats: real-time measurement in vivo.
    The Journal of physiology, 2002, Oct-01, Volume: 544, Issue:Pt 1

    Topics: Adenosine; Adenosine Diphosphate; Animals; Biosensing Techniques; Brain Stem; Computer Systems; Electric Stimulation; Enzyme Inhibitors; Escape Reaction; Hypothalamus; Inosine; Microelectrodes; Rats; Rats, Sprague-Dawley; Solitary Nucleus; Time Factors

2002
Extracellular purines from cells of seminiferous tubules.
    Molecular and cellular biochemistry, 2003, Volume: 245, Issue:1-2

    Topics: 5'-Nucleotidase; Adenine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Animals; Cells, Cultured; Dipyridamole; Enzyme Inhibitors; Extracellular Space; Germ Cells; Kinetics; Male; Paracrine Communication; Phosphodiesterase Inhibitors; Purines; Rats; Rats, Wistar; Receptors, Purinergic; Seminiferous Tubules; Sertoli Cells; Thioinosine

2003
Extracellular conversion of guanine-based purines to guanosine specifically enhances astrocyte glutamate uptake.
    Brain research, 2003, May-16, Volume: 972, Issue:1-2

    Topics: Adenosine Diphosphate; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Guanine; Guanosine; Guanosine Monophosphate; Guanosine Triphosphate; Rats; Rats, Wistar

2003
Cilostazol, an inhibitor of type 3 phosphodiesterase, stimulates large-conductance, calcium-activated potassium channels in pituitary GH3 cells and pheochromocytoma PC12 cells.
    Endocrinology, 2004, Volume: 145, Issue:3

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Action Potentials; Adenoma; Adenosine; Adenosine Diphosphate; Animals; Calcium Channels, L-Type; Cilostazol; Cyclic Nucleotide Phosphodiesterases, Type 3; Electric Conductivity; Enzyme Inhibitors; Kinetics; Large-Conductance Calcium-Activated Potassium Channels; PC12 Cells; Phosphodiesterase Inhibitors; Pituitary Gland, Anterior; Pituitary Neoplasms; Potassium Channels, Calcium-Activated; Rats; Tetrazoles

2004
Anticonvulsant effect of GMP depends on its conversion to guanosine.
    Brain research, 2004, Apr-16, Volume: 1005, Issue:1-2

    Topics: Adenosine Diphosphate; Animals; Anticonvulsants; Cyclic GMP; Dose-Response Relationship, Drug; Guanosine; Male; Rats; Rats, Wistar; Seizures

2004
Hypoxia induces adenosine release from the rat carotid body.
    Journal of neurochemistry, 2004, Volume: 89, Issue:5

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Carotid Body; Carrier Proteins; Chemoreceptor Cells; Dipyridamole; Enzyme Inhibitors; Hypoxia; In Vitro Techniques; Membrane Transport Proteins; Nucleoside Transport Proteins; Rats; Rats, Wistar; Thioinosine

2004
Regulation of VEGF and bFGF mRNA expression and other proliferative compounds in skeletal muscle cells.
    Angiogenesis, 2004, Volume: 7, Issue:3

    Topics: Adenosine; Adenosine Diphosphate; Animals; Cell Proliferation; Cells, Cultured; Electric Stimulation; Endothelium, Vascular; Fibroblast Growth Factor 2; Gene Expression Regulation; Humans; Indomethacin; Male; Muscle Cells; Muscle Contraction; Muscle, Skeletal; Nitric Oxide; Nitroarginine; Penicillamine; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; RNA, Messenger; Vascular Endothelial Growth Factor A

2004
Amitriptyline enhances extracellular tissue levels of adenosine in the rat hindpaw and inhibits adenosine uptake.
    European journal of pharmacology, 2005, Aug-22, Volume: 518, Issue:2-3

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Biological Transport; Capsaicin; Cell Line, Tumor; Dose-Response Relationship, Drug; Equilibrative-Nucleoside Transporter 2; Extracellular Space; Hindlimb; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Time Factors

2005
Overexpression of Ecto-5'-nucleotidase (CD73) promotes T-47D human breast cancer cells invasion and adhesion to extracellular matrix.
    Cancer biology & therapy, 2007, Volume: 6, Issue:3

    Topics: 5'-Nucleotidase; Adenosine Diphosphate; Breast Neoplasms; Cell Adhesion; Cell Movement; ErbB Receptors; Extracellular Matrix; Humans; Interleukin-8; Neoplasm Invasiveness; RNA, Messenger; RNA, Small Interfering

2007
Effects of ecto-5'-nucleotidase on human breast cancer cell growth in vitro and in vivo.
    Oncology reports, 2007, Volume: 17, Issue:6

    Topics: 5'-Nucleotidase; Adenosine Diphosphate; Animals; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Enzyme Inhibitors; Female; Humans; Male; Mice; Mice, Nude; Neovascularization, Pathologic; Xenograft Model Antitumor Assays

2007
The relationship between constitutive ATP release and its extracellular metabolism in isolated rat kidney glomeruli.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2007, Volume: 58, Issue:2

    Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Cells, Cultured; Kidney Glomerulus; Male; Rats; Rats, Wistar

2007
Ecto-5'-nucleotidase/CD73 inhibition by quercetin in the human U138MG glioma cell line.
    Biochimica et biophysica acta, 2007, Volume: 1770, Issue:9

    Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine Diphosphate; Cell Line, Tumor; Cell Proliferation; Glioma; Humans; Quercetin; RNA, Messenger

2007
Ecto-5'-nucleotidase promotes invasion, migration and adhesion of human breast cancer cells.
    Journal of cancer research and clinical oncology, 2008, Volume: 134, Issue:3

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Breast Neoplasms; Cell Adhesion; Cell Movement; Extracellular Matrix; Female; Humans; Neoplasm Invasiveness; Transfection

2008
Lack of effect of extracellular adenosine generation and signaling on renal erythropoietin secretion during hypoxia.
    American journal of physiology. Renal physiology, 2007, Volume: 293, Issue:5

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Arteries; Carbon Monoxide; Erythropoietin; Extracellular Fluid; Hemodilution; Hypoxia; Kidney; Mice; Mice, Inbred C57BL; Mice, Knockout; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; RNA, Messenger; Signal Transduction

2007
Control of IFN-alphaA by CD73: implications for mucosal inflammation.
    Journal of immunology (Baltimore, Md. : 1950), 2008, Mar-15, Volume: 180, Issue:6

    Topics: 5'-Nucleotidase; Acute Disease; Adenosine Diphosphate; Animals; Colitis; Disease Progression; Down-Regulation; Inflammation Mediators; Interferon-alpha; Interleukin-10; Intestinal Mucosa; Mice; Mice, Inbred C57BL; Mice, Knockout; RNA, Messenger; Trinitrobenzenesulfonic Acid

2008
Role of extracellular nucleotide phosphohydrolysis in intestinal ischemia-reperfusion injury.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2008, Volume: 22, Issue:8

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Base Sequence; Caco-2 Cells; Cell Line; DNA Primers; Enzyme Inhibitors; Extracellular Fluid; Female; Humans; Hydrolysis; Interleukin-1beta; Interleukin-6; Intestinal Mucosa; Intestines; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Purinergic P1; Reperfusion Injury; Signal Transduction

2008
Ischemia-driven expression of CD73 confers tissue protection during liver ischemia/reperfusion.
    Gastroenterology, 2008, Volume: 135, Issue:5

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Disease Models, Animal; Extracellular Fluid; Liver; Mice; Mice, Knockout; Reperfusion Injury

2008
Loss of purinergic vascular regulation in the colon during colitis is associated with upregulation of CD39.
    American journal of physiology. Gastrointestinal and liver physiology, 2009, Volume: 296, Issue:2

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antigens, CD; Antigens, Differentiation; Apyrase; Arterioles; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Electric Stimulation; Enzyme Inhibitors; Macrophages; Male; Mice; RNA, Messenger; Splanchnic Circulation; Submucous Plexus; Sympathetic Nervous System; Up-Regulation; Vasoconstriction

2009
Studies of the extracellular ATP-adenosine pathway in human urinary tract epithelial cells.
    Pharmacology, 2009, Volume: 84, Issue:4

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Biosynthetic Pathways; Cell Line; Epithelial Cells; Humans; Neutrophils; Nucleotidases; Urinary Tract

2009
Adenosine A1 receptors and microglial cells mediate CX3CL1-induced protection of hippocampal neurons against Glu-induced death.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2010, Volume: 35, Issue:7

    Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine Deaminase; Adenosine Diphosphate; Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Cell Death; Cell Movement; Clodronic Acid; CX3C Chemokine Receptor 1; Erythropoietin; Glutamic Acid; Green Fluorescent Proteins; Hippocampus; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Neurons; Organ Culture Techniques; Rats; Receptor, Adenosine A1; Receptors, Adenosine A2; Receptors, Chemokine; Xanthines

2010
Altered purinergic signaling in CD73-deficient mice inhibits tumor progression.
    European journal of immunology, 2011, Volume: 41, Issue:5

    Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Triphosphatases; Animals; Apyrase; Cell Proliferation; Disease Progression; Interferon-gamma; Lectins, C-Type; Lymphocytes; Lymphocytes, Tumor-Infiltrating; Macrophages; Mannose Receptor; Mannose-Binding Lectins; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Knockout; Neoplasm Metastasis; Nitric Oxide Synthase Type II; Purines; Receptors, Cell Surface; RNA, Messenger; Signal Transduction; T-Lymphocytes, Regulatory

2011
CD73 has distinct roles in nonhematopoietic and hematopoietic cells to promote tumor growth in mice.
    The Journal of clinical investigation, 2011, Volume: 121, Issue:6

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Chemotaxis, Leukocyte; Disease Progression; Female; Immunotherapy, Adoptive; Lymphocytes, Tumor-Infiltrating; Lymphoma, Non-Hodgkin; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Molecular Targeted Therapy; Ovarian Neoplasms; Peritoneal Neoplasms; Radiation Chimera; Second Messenger Systems; T-Lymphocytes; T-Lymphocytes, Regulatory; Tumor Burden

2011
Role of the ecto-nucleotidases in the cooperative effect of adenosine and neuropeptide-S on locomotor activity in mice.
    Pharmacology, biochemistry, and behavior, 2011, Volume: 99, Issue:4

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Enzyme Inhibitors; Injections, Intraventricular; Male; Mice; Motor Activity; Neostriatum; Neuropeptides

2011
Alterations in the extracellular catabolism of nucleotides are involved in the antiproliferative effect of quercetin in human bladder cancer T24 cells.
    Urologic oncology, 2013, Volume: 31, Issue:7

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Synergism; Extracellular Space; GPI-Linked Proteins; Humans; Hydrolysis; Nucleotides; Quercetin; Time Factors; Urinary Bladder Neoplasms

2013
Neuronal adenosine release, and not astrocytic ATP release, mediates feedback inhibition of excitatory activity.
    Proceedings of the National Academy of Sciences of the United States of America, 2012, Apr-17, Volume: 109, Issue:16

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Astrocytes; Brain; CA1 Region, Hippocampal; Excitatory Postsynaptic Potentials; Feedback, Physiological; GPI-Linked Proteins; Long-Term Synaptic Depression; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Patch-Clamp Techniques; Receptor, Adenosine A1; Seizures

2012
Inhibition of CD73 improves B cell-mediated anti-tumor immunity in a mouse model of melanoma.
    Journal of immunology (Baltimore, Md. : 1950), 2012, Sep-01, Volume: 189, Issue:5

    Topics: 5'-Nucleotidase; Adenosine Diphosphate; Animals; Antineoplastic Agents; B-Lymphocytes; Cell Line, Tumor; Cells, Cultured; Disease Models, Animal; Female; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Nude; Th1 Cells; Th17 Cells

2012
Extracellular 2',3'-cAMP-adenosine pathway in proximal tubular, thick ascending limb, and collecting duct epithelial cells.
    American journal of physiology. Renal physiology, 2013, Jan-01, Volume: 304, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Epithelial Cells; Kidney Tubules, Collecting; Kidney Tubules, Proximal; Loop of Henle; Male; Rats; Rats, Sprague-Dawley; Xanthines

2013
Potential prognostic biomarker CD73 regulates epidermal growth factor receptor expression in human breast cancer.
    IUBMB life, 2012, Volume: 64, Issue:11

    Topics: 5'-Nucleotidase; Adenocarcinoma, Mucinous; Adenosine Diphosphate; Adult; Aged; Apoptosis; Biomarkers, Tumor; Blotting, Western; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Lobular; Carcinoma, Medullary; Cell Adhesion; Cell Movement; Cell Proliferation; Electrophoretic Mobility Shift Assay; ErbB Receptors; Female; GPI-Linked Proteins; Humans; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Phosphorylation; Prognosis; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Survival Rate; Tumor Cells, Cultured

2012
Crystal structure of the human ecto-5'-nucleotidase (CD73): insights into the regulation of purinergic signaling.
    Structure (London, England : 1993), 2012, Dec-05, Volume: 20, Issue:12

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Amino Acid Sequence; Catalytic Domain; Coordination Complexes; Crystallography, X-Ray; Enzyme Inhibitors; Flavonoids; GPI-Linked Proteins; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Molecular Sequence Data; Protein Binding; Protein Interaction Domains and Motifs; Protein Structure, Quaternary; Protein Structure, Secondary; Protein Subunits; Signal Transduction; Structural Homology, Protein; Zinc

2012
CD73/5'-ecto-nucleotidase acts as a regulatory factor in osteo-/chondrogenic differentiation of mechanically stimulated mesenchymal stromal cells.
    European cells & materials, 2013, Jan-08, Volume: 25

    Topics: 5'-Nucleotidase; Adenosine Diphosphate; Alkaline Phosphatase; Animals; Antigens, CD; Cell Differentiation; Cell Proliferation; Cells, Cultured; Chondrogenesis; Gene Expression; Male; Mesenchymal Stem Cells; Osteoblasts; Osteogenesis; Rats; Rats, Inbred Lew; Receptor, Adenosine A2A; Signal Transduction

2013
Recruitment of beneficial M2 macrophages to injured spinal cord is orchestrated by remote brain choroid plexus.
    Immunity, 2013, Mar-21, Volume: 38, Issue:3

    Topics: 5'-Nucleotidase; Adenosine Diphosphate; Animals; Antigens, Ly; Blood-Brain Barrier; Cell Movement; Choroid Plexus; CX3C Chemokine Receptor 1; Enzyme Inhibitors; Flow Cytometry; Gene Expression; Green Fluorescent Proteins; Integrin alpha4beta1; Leukocyte Common Antigens; Macrophages; Meninges; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Confocal; Monocytes; Receptors, Chemokine; Reverse Transcriptase Polymerase Chain Reaction; Spinal Cord; Spinal Cord Injuries; Vascular Cell Adhesion Molecule-1

2013
Inhibition of CD73 stimulates the migration and invasion of B16F10 melanoma cells in vitro, but results in impaired angiogenesis and reduced melanoma growth in vivo.
    Oncology reports, 2014, Volume: 31, Issue:2

    Topics: 5'-Nucleotidase; Adenosine Diphosphate; Animals; Antigens, CD; Apyrase; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Extracellular Matrix Proteins; HEK293 Cells; Humans; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Neoplasm Invasiveness; Neovascularization, Pathologic; Purinergic P1 Receptor Agonists

2014
The volatile anesthetic isoflurane increases endothelial adenosine generation via microparticle ecto-5'-nucleotidase (CD73) release.
    PloS one, 2014, Volume: 9, Issue:6

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Amides; Anesthetics, Inhalation; Animals; Antigens, CD; Cadherins; Cell Line, Transformed; Cell-Derived Microparticles; Endothelial Cells; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Isoflurane; Kidney Glomerulus; Male; Mice; Mice, Inbred C57BL; Myosin-Light-Chain Phosphatase; Pyridines; rho-Associated Kinases; Signal Transduction

2014
Role of adenosine signaling on pentylenetetrazole-induced seizures in zebrafish.
    Zebrafish, 2015, Volume: 12, Issue:2

    Topics: Adenine; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine Diphosphate; Animals; Benzyl Compounds; Convulsants; Dipyridamole; Gene Expression Regulation; Genes, fos; Pentylenetetrazole; Phenethylamines; Phosphodiesterase Inhibitors; Seizures; Signal Transduction; Thioinosine; Xanthines; Zebrafish

2015
Different danger signals differently impact on microglial proliferation through alterations of ATP release and extracellular metabolism.
    Glia, 2015, Volume: 63, Issue:9

    Topics: 5'-Nucleotidase; Adenosine; Adenosine A2 Receptor Antagonists; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Apyrase; Cell Line; Cell Proliferation; Cells, Cultured; Enzyme Inhibitors; Extracellular Space; Glutamic Acid; Lipopolysaccharides; Mice, Inbred C57BL; Microglia; Pyrimidines; Receptors, Adenosine A2; Triazoles

2015
Contributions from extracellular sources of adenosine to the ethanol toxicity in zebrafish larvae.
    Reproductive toxicology (Elmsford, N.Y.), 2015, Volume: 53

    Topics: 5'-Nucleotidase; Adenosine Diphosphate; Animals; Dipyridamole; Ethanol; Larva; Motor Activity; Zebrafish

2015
α,β-Methylene-ADP (AOPCP) Derivatives and Analogues: Development of Potent and Selective ecto-5'-Nucleotidase (CD73) Inhibitors.
    Journal of medicinal chemistry, 2015, Aug-13, Volume: 58, Issue:15

    Topics: 5'-Nucleotidase; Adenosine Diphosphate; Animals; Cell Line; Enzyme Inhibitors; Humans; Microsomes, Liver; Models, Molecular; Rats; Spodoptera

2015
CD73 Activity is Dispensable for the Polarization of M2 Macrophages.
    PloS one, 2015, Volume: 10, Issue:8

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Cytokines; Flow Cytometry; GPI-Linked Proteins; Humans; Immunosuppressive Agents; Inflammation; Interferon-gamma; Interleukin-4; Lipopolysaccharides; Macrophage Colony-Stimulating Factor; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Monocytes; Phenotype

2015
Extracellular adenosine produced by ecto-5'-nucleotidase (CD73) regulates macrophage pro-inflammatory responses, nitric oxide production, and favors Salmonella persistence.
    Nitric oxide : biology and chemistry, 2018, 01-30, Volume: 72

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Cytokines; Host-Pathogen Interactions; Inflammation; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type II; RAW 264.7 Cells; Salmonella Infections; Salmonella typhimurium

2018
Adenosine Production by Biomaterial-Supported Mesenchymal Stromal Cells Reduces the Innate Inflammatory Response in Myocardial Ischemia/Reperfusion Injury.
    Journal of the American Heart Association, 2018, 01-13, Volume: 7, Issue:2

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Cells, Cultured; Coculture Techniques; Disease Models, Animal; Enzyme Inhibitors; GPI-Linked Proteins; Humans; Hydrogen Peroxide; Immunity, Innate; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Neutrophils; Rats, Sprague-Dawley; Recovery of Function; Stem Cell Niche; Tissue Scaffolds

2018
The metabolism of ecto-5'-nucleotidase (CD73) inhibitor-α,β-methylene adenosine diphosphate in BALB/c mice.
    Nucleosides, nucleotides & nucleic acids, 2018, Volume: 37, Issue:12

    Topics: 5'-Nucleotidase; Adenosine Diphosphate; Animals; Antineoplastic Agents; Dose-Response Relationship, Drug; Injections, Intravenous; Mice, Inbred BALB C

2018
Enhanced ATP release and CD73-mediated adenosine formation sustain adenosine A
    British journal of pharmacology, 2019, Volume: 176, Issue:18

    Topics: 5'-Nucleotidase; Adenosine; Adenosine A2 Receptor Antagonists; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cell Line, Tumor; Humans; Male; Oxidopamine; Parkinsonian Disorders; Pyrimidines; Rats, Wistar; Receptor, Adenosine A2A; Triazoles

2019
Number of Circulating CD 73-Expressing Lymphocytes Correlates With Survival After Cardiac Arrest.
    Journal of the American Heart Association, 2019, 07-02, Volume: 8, Issue:13

    Topics: 5'-Nucleotidase; Adenosine A2 Receptor Antagonists; Adenosine Diphosphate; Adenosine Monophosphate; Aged; Antigens, CD; Apyrase; Cardiopulmonary Resuscitation; Case-Control Studies; Enzyme Inhibitors; Female; Heart Arrest; Humans; In Vitro Techniques; Leukocyte Count; Lymphocytes; Male; Middle Aged; Myeloid Cells; Prognosis; Reactive Oxygen Species; Triazines; Triazoles; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A

2019
e5NT inhibitor protects acute restraint stress-induced depression by regulating nucleoside release in mice.
    The Journal of pharmacy and pharmacology, 2020, Volume: 72, Issue:11

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Elevated Plus Maze Test; Enzyme Inhibitors; Exploratory Behavior; GPI-Linked Proteins; Hippocampus; Male; Mice; Open Field Test; Restraint, Physical; Stress, Psychological; Uridine

2020
Differential Effects of Intra- and Extravascular ATP on the Diameter of Porcine Vessels at Different Branching Levels Ex Vivo.
    Investigative ophthalmology & visual science, 2020, 10-01, Volume: 61, Issue:12

    Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Animals; Arterioles; Cyclooxygenase Inhibitors; Endovascular Procedures; Enzyme Inhibitors; Ibuprofen; Platelet Aggregation Inhibitors; Retinal Artery; Sus scrofa; Vasoconstriction; Vasodilation

2020
Inhibition of ecto-5'-nucleotidase and adenosine deaminase is able to reverse long-term behavioural effects of early ethanol exposure in zebrafish (Danio rerio).
    Scientific reports, 2020, 10-20, Volume: 10, Issue:1

    Topics: 5'-Nucleotidase; Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Animals; Antisocial Personality Disorder; Behavior, Animal; Disease Models, Animal; Ethanol; Female; Humans; Pregnancy; Prenatal Exposure Delayed Effects; Social Interaction; Zebrafish

2020
CD73 regulates hepatic stellate cells activation and proliferation through Wnt/β-catenin signaling pathway.
    European journal of pharmacology, 2021, Jan-05, Volume: 890

    Topics: 5'-Nucleotidase; Adenosine Diphosphate; Animals; Cell Line; Cell Proliferation; Cells, Cultured; Hepatic Stellate Cells; Male; Mice; Mice, Inbred C57BL; Rats; Wnt Signaling Pathway

2021