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adenosine diphosphate and 2-methylthio-atp

adenosine diphosphate has been researched along with 2-methylthio-atp in 62 studies

Research

Studies (62)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (1.61)	18.7374
1990's	29 (46.77)	18.2507
2000's	30 (48.39)	29.6817
2010's	2 (3.23)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Boyer, JL; Brizzolara, AL; Burnstock, G; Fischer, B; Harden, TK; Hoyle, CH; Jacobson, KA; Knight, GE; Ziganshin, AU; Zimmet, J	1
Boeynaems, JM; Communi, D; Parmentier, M	1
Harden, TK; Schachter, JB	1
Jacobson, KA; Jarvis, MF; Williams, M	1
Boyer, JL; Corbitt, J; Harden, TK; Jacobson, KA; Ji, XD; Kim, HS; Lacy, J; Ravi, G; Waldo, GL	1
Boeynaems, JM; Communi, D; Gonzalez, NS; Labouret, C; Le Poul, E; Marteau, F; Savi, P	1
Bertrand, G; Gross, R; Loubatières-Mariani, MM; Ribes, G	1
Burnstock, G; Houston, DA; Vanhoutte, PM	1
Balcar, VJ; Bennett, MR; Killinger, S; Li, Y	1
Ferrier, J; Yu, H	1
Gardell, SJ; Shi, XP; Yin, KC	1
Cage, PA; Humphries, RG; Ingall, AH; Leff, P; Tomlinson, W	1
Breittmayer, JP; Feolde, E; Frelin, C; Vigne, P	1
Conigrave, AD; Cook, DI; Delbridge, L; Gibb, CA	1
Bertics, PJ; Daugherty, SK; Denlinger, LC; Firestein, GS; Leventhal, PS; Proctor, RA; Tanke, T; van de Loo, JW	1
Cobbold, PH; Dixon, CJ; Green, AK	1
Barnard, EA; Burnstock, G; King, BF; Simon, J; Webb, TE	1
Langley, D; Pearce, B	1
Chessell, IP; Humphrey, PP; Michel, AD	1
Harden, TK; Nicholas, RA; Schachter, JB; Sromek, SM	1
Albert, JL; Boarder, MR; Boyle, JP; Challiss, RA; Gubby, SE; Roberts, JA	1
Vischer, UM; Wollheim, CB	1
Breittmayer, JP; Frelin, C; Gachet, C; Hechler, B; Léon, C; Vigne, P	1
Duchêne, AD; Takeda, K	1
Bobbin, RP; Chen, C	1
Najbar-Kaszkiel, AT; Rand, MJ	1
Gordjani, N; Greger, R; Kerstan, D; Leipziger, J; Nitschke, R	1
Cha, SH; Endou, H; Sekine, T	1
Boyer, JL; Harden, TK; Nicholas, RA; Palmer, RK; Schachter, JB	1
Erik, A; Gutierrez, AM; Lou, X; Persson, G; Ring, A	1
Collett, A; Inglis, SK; McAlroy, HL; Olver, RE; Wilson, SM	1
Figarella, C; Kammouni, W; Merten, MD; Picher, M; Saleh, A	1
Ias'ko, MV; Skoblov, IuS; Skoblov, MIu	1
Avruch, J; Gottfried, C; Kang, Y; Lenz, G; Luo, Z; Neary, JT; Nie, WJ; Rodnight, R	1
Barnard, EA; Brown, DA; Filippov, AK	1
Fam, SR; Gallagher, CJ; Salter, MW	1
Dixon, CJ	1
Belardinelli, L; Erga, KS; Liang, HX; Seubert, CN; Shryock, JC; Wu, L	1
Chiu, CT; Pan, SL; Tsai, YJ; Wang, CC; Wu, WB; Yang, CM	1
Boeynaems, JM; Castro, E; Communi, D; Delicado, EG; Jiménez, AI; Miras-Portugal, MT	1
Erdélyi, F; Sperlágh, B; Szabó, G; Vizi, ES	1
Ferreira, ZS; Markus, RP	1
Laitinen, JT; Miettinen, R; Raidaru, G; Uri, A	1
Edwards, RM	1
Bell, PD; Johansson, A; Kovacs, G; Liu, R; Persson, AE; Peti-Peterdi, J	1
Johannwille, B; Neye, H; Verspohl, EJ; Waheed, A	1
Borvendeg, SJ; Illes, P; Luthardt, J; Poelchen, W; Sperlagh, B; Wirkner, K	1
Chambers, JK; Emson, PC; Moore, DJ; Murdock, PR	1
Feldkamp, T; Heemann, U; Herget-Rosenthal, S; Horbelt, M; Kribben, A; Lange, B; Philipp, T; Pietruck, F	1
Au, CL; Ko, WH; Yip, CY	1
Chuai, M; Morino, T; Nakamura, Y; Ogata, T; Schubert, P; Yamamoto, H	1
Chalimoniuk, M; Gendron, FP; González, FA; Shen, S; Strosznajder, J; Sun, GY; Weisman, GA	1
Fatkullin, IF; Vafina, ZR; Ziganshin, AU	1
Buljubasich, R; Ventura, S	1
Gachet, C; Inoue, K; Kato, F; Kawamura, M	1
Mulè, F; Naccari, D; Serio, R	1
El-Ashmawy, IM; Franke, H; Harsch, JI; Illes, P; Kittner, H; Krügel, U; Seidel, B	1
Huang, JS; Khasawneh, FT; Lam, SC; Le Breton, GC; Mir, F; Srinivasan, S	1
Fraga, S; Gonçalves, J; Queiroz, G; Quintas, C	1
Ren, LM; Wang, M	1
Boehm, S; Chandaka, GK; Drobny, H; Salzer, I; Schicker, KW	1
Cherezov, V; Gao, ZG; Han, GW; Jacobson, KA; Jiang, H; Katritch, V; Li, T; Ma, L; Müller, CE; Paoletta, S; Stevens, RC; Wu, B; Yang, H; Zhang, D; Zhang, J; Zhang, K; Zhang, W; Zhao, Q	1

Reviews

1 review(s) available for adenosine diphosphate and 2-methylthio-atp

Article	Year
Purine and pyrimidine (P2) receptors as drug targets. Journal of medicinal chemistry, 2002, Sep-12, Volume: 45, Issue:19 Topics: Adenosine Triphosphate; Animals; Drug Design; Humans; Ligands; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyrimidines; Receptors, Purinergic P2; Uridine Triphosphate	2002

Other Studies

61 other study(ies) available for adenosine diphosphate and 2-methylthio-atp

Article	Year
Identification of potent, selective P2Y-purinoceptor agonists: structure-activity relationships for 2-thioether derivatives of adenosine 5'-triphosphate. Journal of medicinal chemistry, 1993, Nov-26, Volume: 36, Issue:24 Topics: Adenine Nucleotides; Animals; Aorta; Colon; Enzyme Activation; Erythrocyte Membrane; Guinea Pigs; Male; Mesenteric Arteries; Muscle Relaxation; Muscle, Smooth; Rabbits; Receptors, Purinergic P2; Structure-Activity Relationship; Sulfides; Turkeys; Type C Phospholipases; Vas Deferens	1993
Cloning, functional expression and tissue distribution of the human P2Y6 receptor. Biochemical and biophysical research communications, 1996, May-15, Volume: 222, Issue:2 Topics: Adenine Nucleotides; Amino Acid Sequence; Animals; Base Sequence; Cell Line; Cloning, Molecular; DNA, Complementary; Female; Gene Library; Humans; Inositol 1,4,5-Trisphosphate; Intestinal Mucosa; Leukocytes; Molecular Sequence Data; Open Reading Frames; Organ Specificity; Placenta; Pregnancy; Rats; Receptors, Purinergic P2; Recombinant Proteins; RNA, Messenger; Sequence Homology, Amino Acid; Spleen; Thymus Gland; Transfection	1996
An examination of deoxyadenosine 5'(alpha-thio)triphosphate as a ligand to define P2Y receptors and its selectivity as a low potency partial agonist of the P2Y1 receptor. British journal of pharmacology, 1997, Volume: 121, Issue:2 Topics: Adenosine Triphosphate; Dose-Response Relationship, Drug; Humans; Radioligand Assay; Receptors, Purinergic P2; Receptors, Purinergic P2Y1	1997
Quantitation of the P2Y(1) receptor with a high affinity radiolabeled antagonist. Molecular pharmacology, 2002, Volume: 62, Issue:5 Topics: Adenosine Diphosphate; Animals; Cells, Cultured; Female; Humans; Insecta; Purinergic P2 Receptor Antagonists; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Tritium	2002
Pharmacological characterization of the human P2Y13 receptor. Molecular pharmacology, 2003, Volume: 64, Issue:1 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cell Membrane; CHO Cells; Cricetinae; Cyclic AMP; Female; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Inositol Phosphates; Kinetics; Receptors, Purinergic P2; Thionucleotides	2003
P2 purinoceptor agonists stimulate somatostatin secretion from dog pancreas. European journal of pharmacology, 1990, Jul-03, Volume: 182, Issue:2 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Anesthesia; Animals; Dogs; Glucagon; In Vitro Techniques; Insulin; Insulin Secretion; Pancreas; Receptors, Purinergic; Somatostatin; Thionucleotides	1990
Different P2-purinergic receptor subtypes of endothelium and smooth muscle in canine blood vessels. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:2 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Endothelium; Muscle Contraction; Muscle, Smooth, Vascular; Receptors, Purinergic; Thionucleotides	1987
Autoradiography of P2x ATP receptors in the rat brain. British journal of pharmacology, 1995, Volume: 115, Issue:2 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Autoradiography; Binding, Competitive; Brain; Brain Stem; Cerebellum; Cerebral Cortex; Dilazep; Female; Hippocampus; Ligands; Male; Ouabain; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Structure-Activity Relationship; Suramin; Thalamus; Thionucleotides	1995
Mechanisms of ATP-induced Ca2+ signaling in osteoclasts. Cellular signalling, 1994, Volume: 6, Issue:8 Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Guanosine Diphosphate; Magnesium; Osteoclasts; Pertussis Toxin; Rabbits; Receptors, Purinergic P2; Signal Transduction; Thionucleotides; Uridine Triphosphate; Virulence Factors, Bordetella	1994
Human erythroleukemic (HEL) cells express a platelet P2T-like ADP receptor. Thrombosis research, 1995, Feb-01, Volume: 77, Issue:3 Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Biological Transport; Blood Platelets; Calcium; Humans; Leukemia, Erythroblastic, Acute; Megakaryocytes; Neoplasm Proteins; Neoplastic Stem Cells; Platelet Activation; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Thionucleotides; Tumor Cells, Cultured; Uridine Triphosphate	1995
FPL 66096: a novel, highly potent and selective antagonist at human platelet P2T-purinoceptors. British journal of pharmacology, 1994, Volume: 113, Issue:3 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Guinea Pigs; Humans; In Vitro Techniques; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Rabbits; Theophylline; Thionucleotides	1994
Characterization of the effects of 2-methylthio-ATP and 2-chloro-ATP on brain capillary endothelial cells: similarities to ADP and differences from ATP. British journal of pharmacology, 1994, Volume: 112, Issue:3 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood-Brain Barrier; Capillaries; Endothelium, Vascular; Nerve Tissue Proteins; Purinergic P2 Receptor Antagonists; Rats; Thionucleotides; Type C Phospholipases	1994
Pharmacological characterization of the nucleotide receptors that mobilize Ca2+ ions in human parathyroid cells. The Journal of endocrinology, 1994, Volume: 142, Issue:2 Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Fura-2; Humans; Microscopy, Fluorescence; Parathyroid Glands; Receptors, Purinergic P2; Thionucleotides; Uridine Triphosphate	1994
Protection of mice from endotoxic death by 2-methylthio-ATP. Proceedings of the National Academy of Sciences of the United States of America, 1994, Jun-21, Volume: 91, Issue:13 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cell Membrane; Death; Endotoxins; Escherichia coli; GTP Phosphohydrolases; Kinetics; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Shock, Septic; Thionucleotides	1994
Actions of ADP, but not ATP, on cytosolic free Ca2+ in single rat hepatocytes mimicked by 2-methylthioATP. British journal of pharmacology, 1995, Volume: 116, Issue:3 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aequorin; Animals; Calcium; Cytosol; Liver; Male; Purinergic P2 Receptor Agonists; Rats; Rats, Wistar; Thionucleotides	1995
Characterisation of a recombinant P2Y purinoceptor. European journal of pharmacology, 1995, Nov-30, Volume: 291, Issue:3 Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Animals; Brain; Cell Line; Electrophysiology; Inositol Phosphates; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Recombinant Proteins; Suramin; Thionucleotides; Triazines; Uridine Triphosphate; Xenopus	1995
Purine- and pyrimidine nucleotide-stimulated changes in intracellular calcium concentration in cultured astrocytes. Receptors & channels, 1996, Volume: 4, Issue:4 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Astrocytes; Calcium; Cells, Cultured; Purine Nucleotides; Pyrimidine Nucleotides; Rats; Thionucleotides	1996
Functional evidence for multiple purinoceptor subtypes in the rat medial vestibular nucleus. Neuroscience, 1997, Volume: 77, Issue:3 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Evoked Potentials; In Vitro Techniques; Male; Neurons; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Theophylline; Thionucleotides; Time Factors; Vestibular Nuclei	1997
HEK293 human embryonic kidney cells endogenously express the P2Y1 and P2Y2 receptors. Neuropharmacology, 1997, Volume: 36, Issue:9 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cell Line; Cricetinae; Humans; In Vitro Techniques; Inositol Phosphates; Kidney; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y2; Stimulation, Chemical; Thionucleotides	1997
Regulation of brain capillary endothelial cells by P2Y receptors coupled to Ca2+, phospholipase C and mitogen-activated protein kinase. British journal of pharmacology, 1997, Volume: 122, Issue:5 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood-Brain Barrier; Brain; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Capillaries; Cells, Cultured; Cyclic AMP; Cytosol; Endothelium, Vascular; Enzyme Activation; Inositol Phosphates; Phosphorylation; Rats; Rats, Wistar; Receptors, Purinergic P2; Thionucleotides; Type C Phospholipases; Uridine Triphosphate	1997
Purine nucleotides induce regulated secretion of von Willebrand factor: involvement of cytosolic Ca2+ and cyclic adenosine monophosphate-dependent signaling in endothelial exocytosis. Blood, 1998, Jan-01, Volume: 91, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenine Nucleotides; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Triphosphate; Calcium; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytoplasmic Granules; Endothelium, Vascular; Enzyme Inhibitors; Exocytosis; Humans; Receptors, Purinergic P1; Receptors, Purinergic P2; Second Messenger Systems; Secretory Rate; Thionucleotides; Thrombin; Umbilical Veins; von Willebrand Factor	1998
ATP derivatives are antagonists of the P2Y1 receptor: similarities to the platelet ADP receptor. Molecular pharmacology, 1998, Volume: 53, Issue:4 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood Platelets; Calcium; Drug Synergism; Edetic Acid; Humans; Intracellular Fluid; Jurkat Cells; Membrane Proteins; Purinergic P2 Receptor Antagonists; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Thionucleotides	1998
P2Y- and P2U-mediated increases in internal calcium in single bovine aortic endothelial cells in primary culture. Endothelium : journal of endothelial cell research, 1997, Volume: 5, Issue:4 Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Cattle; Cells, Cultured; Ion Transport; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Thionucleotides; Uridine Triphosphate	1997
P2X receptors in cochlear Deiters' cells. British journal of pharmacology, 1998, Volume: 124, Issue:2 Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cochlea; Colforsin; Dose-Response Relationship, Drug; Enzyme Activation; Guinea Pigs; Patch-Clamp Techniques; Protein Kinases; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Tetradecanoylphorbol Acetate; Thionucleotides; Uridine Triphosphate; Vasodilator Agents; Vestibular Nucleus, Lateral	1998
Effects of P2-receptor agonists on sympathetic neuroeffector transmission in the rat isolated anococcygeus muscle. Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 357, Issue:5 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Desipramine; Electric Stimulation; Enzyme Inhibitors; Idazoxan; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; NADP; NG-Nitroarginine Methyl Ester; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Synaptic Transmission; Thionucleotides	1998
Luminal ATP induces K+ secretion via a P2Y2 receptor in rat distal colonic mucosa. Pflugers Archiv : European journal of physiology, 1998, Volume: 436, Issue:5 Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Barium; Biological Transport; Colon; Female; In Vitro Techniques; Intestinal Mucosa; Ion Channels; Male; Membrane Potentials; Polymerase Chain Reaction; Potassium; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Thionucleotides; Uridine Triphosphate	1998
P2 purinoceptor localization along rat nephron and evidence suggesting existence of subtypes P2Y1 and P2Y2. The American journal of physiology, 1998, Volume: 274, Issue:6 Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Calcium Channel Blockers; Gallic Acid; Kidney Glomerulus; Kidney Tubules, Collecting; Male; Nephrons; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Suramin; Thionucleotides; Uridine Triphosphate	1998
Agonist action of adenosine triphosphates at the human P2Y1 receptor. Molecular pharmacology, 1998, Volume: 54, Issue:6 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Calcium; Cell Line; Dose-Response Relationship, Drug; Humans; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2Y1; Thionucleotides; Tumor Cells, Cultured	1998
Ca2+ response of rat mesangial cells to ATP analogues. European journal of pharmacology, 1999, Mar-12, Volume: 369, Issue:1 Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Glomerular Mesangium; Rats; Rats, Sprague-Dawley; Thionucleotides; Uridine Triphosphate	1999
Effect of luminal nucleotides on Cl- secretion and Na+ absorption in distal bronchi. Pflugers Archiv : European journal of physiology, 1999, Volume: 438, Issue:5 Topics: Absorption; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Bronchi; Calcium; Chelating Agents; Chlorides; Egtazic Acid; Electric Conductivity; Microelectrodes; Nucleotides; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Sodium; Swine; Thapsigargin; Thionucleotides; Uridine Diphosphate; Uridine Triphosphate	1999
Characterization of a diadenosine tetraphosphate-receptor distinct from the ATP-purinoceptor in human tracheal gland cells. European journal of pharmacology, 1999, Nov-12, Volume: 384, Issue:1 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Binding, Competitive; Calcium; Cells, Cultured; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Humans; Hydrolysis; Proteinase Inhibitory Proteins, Secretory; Proteins; Receptors, Purinergic P2; Secretory Leukocyte Peptidase Inhibitor; Suramin; Thionucleotides; Trachea	1999
[Preparation of 32P-labelled 2-methylthioadenosine di- and triphosphates]. Bioorganicheskaia khimiia, 1999, Volume: 25, Issue:9 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Chromatography, High Pressure Liquid; Phosphorus Radioisotopes; Phosphorylation; Radiochemistry; Thionucleotides	1999
P(2Y) purinoceptor subtypes recruit different mek activators in astrocytes. British journal of pharmacology, 2000, Volume: 129, Issue:5 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Astrocytes; Cells, Cultured; Cerebral Cortex; Enzyme Activators; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-raf; Purinergic P2 Receptor Agonists; Rats; Rats, Inbred F344; Receptors, Purinergic P2; Reverse Transcriptase Polymerase Chain Reaction; Thionucleotides; Uridine Triphosphate	2000
The P2Y(1) receptor closes the N-type Ca(2+) channel in neurones, with both adenosine triphosphates and diphosphates as potent agonists. British journal of pharmacology, 2000, Volume: 129, Issue:6 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Astrocytoma; Brain Neoplasms; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, N-Type; Neurons; Purinergic P2 Receptor Agonists; Rats; Receptors, Purinergic P2Y1; RNA; Signal Transduction; Thionucleotides; Tumor Cells, Cultured	2000
P2Y(1) purinoceptor-mediated Ca(2+) signaling and Ca(2+) wave propagation in dorsal spinal cord astrocytes. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, Apr-15, Volume: 20, Issue:8 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Astrocytes; Calcium; Calcium Signaling; Cells, Cultured; Embryo, Mammalian; Female; Posterior Horn Cells; Pregnancy; Rats; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; RNA, Messenger; Thionucleotides; Uridine Triphosphate	2000
Evidence that 2-methylthioATP and 2-methylthioADP are both agonists at the rat hepatocyte P2Y(1) receptor. British journal of pharmacology, 2000, Volume: 130, Issue:3 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium Signaling; Liver; Male; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P2Y1; Thionucleotides; Uridine Triphosphate	2000
Role of A(2A)-adenosine receptor activation for ATP-mediated coronary vasodilation in guinea-pig isolated heart. British journal of pharmacology, 2000, Volume: 130, Issue:5 Topics: Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Coronary Vessels; Glyburide; Guinea Pigs; NG-Nitroarginine Methyl Ester; Perfusion; Receptors, Purinergic P1; Thionucleotides; Vasodilation	2000
P2Y(2) receptor-stimulated phosphoinositide hydrolysis and Ca(2+) mobilization in tracheal epithelial cells. American journal of physiology. Lung cellular and molecular physiology, 2000, Volume: 279, Issue:2 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Dogs; Dose-Response Relationship, Drug; Female; Hydrolysis; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Lithium Chloride; Male; Phosphatidylinositols; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Respiratory Mucosa; Thionucleotides; Trachea; Uridine Triphosphate	2000
Coexpression of several types of metabotropic nucleotide receptors in single cerebellar astrocytes. Journal of neurochemistry, 2000, Volume: 75, Issue:5 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Astrocytes; Calcium; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Intracellular Fluid; Pertussis Toxin; Protein Kinase C; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P2; Stimulation, Chemical; Suramin; Thionucleotides; Uridine Triphosphate; Virulence Factors, Bordetella	2000
Local regulation of [(3)H]-noradrenaline release from the isolated guinea-pig right atrium by P(2X)-receptors located on axon terminals. British journal of pharmacology, 2000, Volume: 131, Issue:8 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cadmium; Dose-Response Relationship, Drug; Electric Stimulation; Gene Expression; Guinea Pigs; Heart Atria; Hippocampus; In Vitro Techniques; Male; Norepinephrine; omega-Conotoxin GVIA; Presynaptic Terminals; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; RNA; Superior Cervical Ganglion; Tetrodotoxin; Theobromine; Thionucleotides; Time Factors; Tritium; Xanthines	2000
Characterisation of P2Y(1)-like receptor in cultured rat pineal glands. European journal of pharmacology, 2001, Volume: 415, Issue:2-3 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adrenergic alpha-Agonists; Animals; Cells, Cultured; Cyclic AMP; Female; Male; Norepinephrine; Phosphodiesterase Inhibitors; Pineal Gland; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Serotonin; Signal Transduction; Thionucleotides; Type C Phospholipases	2001
[(35)S]GTPgammaS autoradiography reveals a wide distribution of G(i/o)-linked ADP receptors in the nervous system: close similarities with the platelet P2Y(ADP) receptor. Journal of neurochemistry, 2001, Volume: 77, Issue:2 Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Adrenal Medulla; Animals; Autoradiography; Blood Platelets; Brain; Brain Chemistry; Capillaries; Cell Line; Dithiothreitol; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Glioma; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Heterotrimeric GTP-Binding Proteins; Macromolecular Substances; Magnetic Resonance Spectroscopy; Male; Membrane Proteins; Nerve Tissue Proteins; Neuroglia; Organ Specificity; Rats; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Signal Transduction; Sulfhydryl Reagents; Sulfur Radioisotopes; Thionucleotides; Tumor Cells, Cultured; Uracil Nucleotides; Xanthines	2001
Basolateral, but not apical, ATP inhibits vasopressin action in rat inner medullary collecting duct. European journal of pharmacology, 2002, Mar-08, Volume: 438, Issue:3 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cell Membrane Permeability; Dose-Response Relationship, Drug; In Vitro Techniques; Kidney Medulla; Kidney Tubules, Collecting; Male; Osmosis; Rats; Rats, Sprague-Dawley; Thionucleotides; Uridine Triphosphate; Vasopressins; Water	2002
Purinergic receptor signaling at the basolateral membrane of macula densa cells. Journal of the American Society of Nephrology : JASN, 2002, Volume: 13, Issue:5 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Benzofurans; Calcium; Cytosol; Dose-Response Relationship, Drug; Estrenes; Female; Fura-2; Imidazoles; Kidney Glomerulus; Microscopy, Confocal; Pyrrolidinones; Rabbits; Receptors, Purinergic; Signal Transduction; Suramin; Thionucleotides; Uridine Triphosphate	2002
Effect of purinergic agonists and antagonists on insulin secretion from INS-1 cells (insulinoma cell line) and rat pancreatic islets. Canadian journal of physiology and pharmacology, 2002, Volume: 80, Issue:6 Topics: Adenosine Deaminase; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cell Line; Estrenes; Female; Glucose; Insulin; Insulinoma; Islets of Langerhans; Male; Pancreatic Neoplasms; Phosphodiesterase Inhibitors; Purinergic Agonists; Purinergic Antagonists; Purines; Pyrrolidinones; Rats; Rats, Wistar; Thionucleotides; Uridine Triphosphate; Xanthines	2002
P2Y(1) receptor activation inhibits NMDA receptor-channels in layer V pyramidal neurons of the rat prefrontal and parietal cortex. Neurochemistry international, 2003, Volume: 42, Issue:2 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Algorithms; Animals; Cerebral Cortex; Electric Stimulation; Excitatory Postsynaptic Potentials; Male; Membrane Potentials; Microelectrodes; Parietal Lobe; Patch-Clamp Techniques; Prefrontal Cortex; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyramidal Cells; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P2Y1; Reflex, Monosynaptic; Thionucleotides	2003
Human Ntera-2/D1 neuronal progenitor cells endogenously express a functional P2Y1 receptor. Neuropharmacology, 2002, Volume: 43, Issue:6 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Antineoplastic Agents; Blotting, Western; Calcium; Cell Membrane; Cells, Cultured; Cyclic AMP; Fluorescence; GTP-Binding Protein alpha Subunits, Gq-G11; Heterotrimeric GTP-Binding Proteins; Humans; Membrane Proteins; Mitogen-Activated Protein Kinases; Neurons; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Receptors, Purinergic P2Y2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stem Cells; Suramin; Thionucleotides; Uridine Triphosphate	2002
ATP protects, by way of receptor-mediated mechanisms, against hypoxia-induced injury in renal proximal tubules. The Journal of laboratory and clinical medicine, 2003, Volume: 141, Issue:1 Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Energy Metabolism; Hemolysis; Hypotonic Solutions; Hypoxia; Kidney Tubules, Proximal; Kinetics; L-Lactate Dehydrogenase; Male; Potassium; Quinazolines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Thionucleotides; Triazoles	2003
Multiple purinergic receptors lead to intracellular calcium increases in cultured rat Sertoli cells. Life sciences, 2003, Feb-14, Volume: 72, Issue:13 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Calcium Signaling; Cells, Cultured; Electrophysiology; Fluorescent Dyes; Fura-2; Immunohistochemistry; Leydig Cells; Male; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sertoli Cells; Thionucleotides; Transcription, Genetic; Uridine Triphosphate	2003
Adenosine triphosphate inhibits cytokine release from lipopolysaccharide-activated microglia via P2y receptors. Brain research, 2003, Aug-15, Volume: 981, Issue:1-2 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Cytokines; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Lipopolysaccharides; Microglia; Nitric Oxide; Purinergic Agonists; Purinergic Antagonists; Purines; Rats; Rats, Wistar; Receptors, Purinergic; RNA, Messenger; Superoxides; Thionucleotides; Tumor Necrosis Factor-alpha	2003
P2X7 nucleotide receptor activation enhances IFN gamma-induced type II nitric oxide synthase activity in BV-2 microglial cells. Journal of neurochemistry, 2003, Volume: 87, Issue:2 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cell Line; Drug Synergism; Enzyme Activation; Enzyme Activators; Enzyme Inhibitors; Interferon-gamma; Mice; Microglia; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Thionucleotides; Uridine Triphosphate	2003
Pharmacological characterization of P2-receptors in human fallopian tubes. Bulletin of experimental biology and medicine, 2004, Volume: 137, Issue:3 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adult; Fallopian Tubes; Female; Humans; In Vitro Techniques; Middle Aged; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Salpingitis; Thionucleotides	2004
Adenosine 5'-triphosphate and noradrenaline are excitatory cotransmitters to the fibromuscular stroma of the guinea pig prostate gland. European journal of pharmacology, 2004, Sep-24, Volume: 499, Issue:3 Topics: Actins; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Atropine; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; Immunohistochemistry; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Prazosin; Prostate; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2X2; Receptors, Purinergic P2X4; Suramin; Tetrodotoxin; Thionucleotides	2004
Direct excitation of inhibitory interneurons by extracellular ATP mediated by P2Y1 receptors in the hippocampal slice. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Dec-01, Volume: 24, Issue:48 Topics: Action Potentials; Adenosine; Adenosine A1 Receptor Agonists; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Astrocytes; Extracellular Fluid; Female; Hippocampus; In Vitro Techniques; Interneurons; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurotransmitter Agents; Organ Specificity; Patch-Clamp Techniques; Purinergic P2 Receptor Agonists; Pyramidal Cells; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptors, Presynaptic; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Species Specificity; Thionucleotides	2004
Evidence for the presence of P2y and P2x receptors with different functions in mouse stomach. European journal of pharmacology, 2005, Apr-18, Volume: 513, Issue:1-2 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; In Vitro Techniques; Mice; Mice, Inbred C57BL; Muscle Contraction; Muscle Relaxation; Receptors, Purinergic P2; Receptors, Purinergic P2X; Stomach; Tetrodotoxin; Thionucleotides	2005
Enhanced food intake after stimulation of hypothalamic P2Y1 receptors in rats: modulation of feeding behaviour by extracellular nucleotides. The European journal of neuroscience, 2006, Volume: 24, Issue:7 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drug Interactions; Eating; Enzyme Inhibitors; Fluorescent Antibody Technique; Food Deprivation; Glial Fibrillary Acidic Protein; Hypothalamus; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type I; Nucleotides; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Signal Transduction; Thionucleotides	2006
The P2Y12 antagonists, 2-methylthioadenosine 5'-monophosphate triethylammonium salt and cangrelor (ARC69931MX), can inhibit human platelet aggregation through a Gi-independent increase in cAMP levels. The Journal of biological chemistry, 2009, Jun-12, Volume: 284, Issue:24 Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Blood Platelets; Cyclic AMP; Dose-Response Relationship, Drug; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine Diphosphate; Humans; In Vitro Techniques; Platelet Aggregation; Purinergic P2 Receptor Antagonists; Receptor, Adenosine A2A; Receptor, PAR-1; Receptors, Epoprostenol; Receptors, Immunologic; Receptors, Prostaglandin; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Purinergic P2Y12; Receptors, Thromboxane A2, Prostaglandin H2; Signal Transduction; Thionucleotides	2009
The P2Y(1) and P2Y(12) receptors mediate autoinhibition of transmitter release in sympathetic innervated tissues. Neurochemistry international, 2009, Volume: 55, Issue:7 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antidepressive Agents, Tricyclic; Arteries; Blotting, Western; Desipramine; Epididymis; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Neurotransmitter Agents; Norepinephrine; Rats; Rats, Wistar; Receptor Cross-Talk; Receptor, Adenosine A1; Receptors, Adrenergic, alpha-2; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Signal Transduction; Sympathetic Nervous System; Thionucleotides; Vas Deferens	2009
[Pharmacological characteristics of contractile responses regulated by P2Y receptors in circular smooth muscle of the rat gastric body]. Yao xue xue bao = Acta pharmaceutica Sinica, 2009, Volume: 44, Issue:5 Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Gastric Fundus; Male; Muscle Contraction; Muscle, Smooth; Purinergic P2 Receptor Agonists; Rats; Rats, Wistar; Receptors, Purinergic P2; Stomach; Thionucleotides; Uridine Triphosphate	2009
Facilitation of transmitter release from rat sympathetic neurons via presynaptic P2Y(1) receptors. British journal of pharmacology, 2011, Volume: 164, Issue:5 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Animals, Newborn; Cell Culture Techniques; Cloning, Molecular; Electric Stimulation; Green Fluorescent Proteins; KCNQ Potassium Channels; Maximum Tolerated Dose; Neurons; Neurotransmitter Agents; Norepinephrine; Patch-Clamp Techniques; PC12 Cells; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Receptors, Presynaptic; Receptors, Purinergic P2Y1; Superior Cervical Ganglion; Synaptic Transmission; Thionucleotides	2011
Agonist-bound structure of the human P2Y12 receptor. Nature, 2014, May-01, Volume: 509, Issue:7498 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Binding Sites; Crystallography, X-Ray; Humans; Ligands; Models, Molecular; Niacin; Protein Conformation; Purinergic P2Y Receptor Agonists; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Substrate Specificity; Sulfonamides; Thionucleotides	2014