adenosine has been researched along with colforsin in 377 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 91 (24.14) | 18.7374 |
| 1990's | 196 (51.99) | 18.2507 |
| 2000's | 66 (17.51) | 29.6817 |
| 2010's | 22 (5.84) | 24.3611 |
| 2020's | 2 (0.53) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| DeLapp, NW; Eckols, K | 1 |
| Dho, S; Foskett, JK; Stewart, K | 1 |
| Lobo, MG; Ribeiro, JA | 1 |
| Ivins, JK; Pittman, RN; Schachter, JB; Wolfe, BB | 1 |
| Gauthier, C; Soustre, H | 1 |
| López-Novoa, JM; Olivera, A; Tomás, M | 1 |
| Kuhne, W; Piper, HM; Schwartz, P; Watanabe, H | 1 |
| Heller, PH; Levine, JD; Taiwo, YO | 1 |
| Byczko, Z; Murphy, MG | 3 |
| Fredholm, BB; Gerwins, P | 2 |
| Ratcliffe, PJ; Tan, CC | 1 |
| Boucher, RC; Clarke, L; Harden, TK; Lazarowski, ER; Mason, SJ | 1 |
| Abrams, TA; Gregory, CY; Hall, MO | 1 |
| LeVier, DG; McCoy, DE; Spielman, WS | 1 |
| Koshland, DE; Martin, PT | 1 |
| Reppert, SM; Rivkees, SA | 1 |
| Graier, WF; Groschner, K; Kukovetz, WR; Schmidt, K | 1 |
| Fukaya, T; Koizumi, H; Kumakiri, M; Ohkawara, A; Ueda, T; Yasui, C | 1 |
| Hultgardh-Nilsson, A; Jonzon, B; Nilsson, J; Querol-Ferrer, V; Ringertz, NR | 1 |
| Richter, J | 1 |
| Czernilofsky, A; Dumont, JE; Ensinger, HA; Lefort, A; Libert, F; Mendla, KD; Van Sande, J; Vassart, G | 1 |
| Belardinelli, L; Lerman, BB; Song, Y; Thedford, S | 1 |
| Harrison, DG; Quillen, JE | 1 |
| Chen, L; Halnon, NJ; Homcy, CJ; Ishikawa, Y; Katsushika, S; Kawabe, J | 1 |
| Asano, K; Iizuka, H; Ito, F; Takahashi, H; Tamura, T; Tsutsui, M | 1 |
| Dumont, JE; Gérard, C; Lefort, A; Libert, F; Parmentier, M; Schiffmann, SN; Vanderhaeghen, JJ; Vassart, G | 1 |
| Araki, T; Hara, H; Kato, H; Kogure, K; Onodera, H | 2 |
| Simmons, DA; Winegrad, AI | 1 |
| Hreniuk, SP; Kaartinen, JM; LaNoue, KF; Martin, LF; Ohisalo, JJ; Ranta, S | 1 |
| Hori, M; Inoue, M; Kamada, T; Kitabatake, A; Kitakaze, M; Sato, H; Takashima, S | 1 |
| Cushing, DJ; Makujina, SR; Mustafa, SJ; Sabouni, MH | 1 |
| Koshland, DE; Morimoto, BH | 1 |
| Tait, JF; Thiagarajan, P | 1 |
| Magistretti, PJ; Sorg, O | 1 |
| Byczko, Z; MacDonald, WF; Moak, CM; Murphy, MG | 1 |
| Fredholm, BB; Jondal, M; Kvanta, A | 1 |
| Ishimura, Y; Kizaki, H; Suzuki, K; Tadakuma, T | 2 |
| Keen, M; Kelly, E; MacDermot, J; Nobbs, P | 1 |
| Greenfield, LJ; Hackett, JT; Linden, J | 2 |
| Chabardès, D; Montégut, M; Siaume-Perez, S; Zhou, Y | 1 |
| Nakagawa-Yagi, Y; Saito, Y; Takada, Y; Takayama, M | 1 |
| Nicholson, D; Sawynok, J; White, TD | 1 |
| Levine, JD; Taiwo, YO | 1 |
| Aassar, OS; Forrest, JN; Kelley, GG | 1 |
| Ameri, A; Jurna, I | 1 |
| Meyers, RL; Paulick, RP; Rudolph, AM | 1 |
| Brownlee, RD; Langille, BL | 1 |
| Dahlman, D; MacLeod, KM; McKinley, JB | 1 |
| Heppel, LA; Huang, NN; Wang, DJ | 1 |
| Olianas, MC; Onali, P | 1 |
| Barron, HV; Forrest, JN; Kelley, GG; Poeschla, EM | 1 |
| Baldessarini, RJ; Booth, RG | 1 |
| Ibayashi, S; Meno, JR; Ngai, AC; Winn, HR | 1 |
| Fukaya, T; Koizumi, H; Ohkawara, A; Osawa, Y; Ueda, T; Yasui, C | 1 |
| Daval, JL; Deckert, J; Marangos, PJ; Morgan, PF; Nakajima, T | 1 |
| Ribeiro, JA; Sebastião, AM | 1 |
| Hirota, K; Kadowaki, K; Kiyama, H; Koike, K; Miyake, A; Ohmichi, M; Tanizawa, O | 1 |
| Yagil, Y | 1 |
| Iizuka, H; Takahashi, H; Tamura, T; Tsutsui, M | 1 |
| Mante, S; Minneman, KP | 1 |
| Schepp, W; Soll, AH; Walsh, JH | 1 |
| Gobran, LI; Rooney, SA | 1 |
| Delicado, EG; Miras-Portugal, MT; Ribeiro, JA; Rodrigues, A; Sebastiao, AM; Sen, RP | 1 |
| Boutterin, MC; Doye, V; Sobel, A | 1 |
| Aronstam, RS; Catravas, JD; Legrand, AB; Narayanan, TK; Ryan, US | 2 |
| King, AD; Milavec-Krizman, M; Müller-Schweinitzer, E | 1 |
| Besharse, JC; Iuvone, PM | 1 |
| Stinnakre, J; Van Renterghem, C | 1 |
| Aitken, RJ; Irvine, S; Mattei, A | 1 |
| Browning, ET; Etgen, AM | 1 |
| Björnsson, OG; Kobayashi, K; Williamson, JR | 1 |
| Brady, MJ; Nairn, AC; Nichols, RA; Palfrey, HC | 1 |
| Berry-Kravis, E; Dawson, G; Derechin, V; Kazmierczak, BI | 1 |
| Bertrand, G; Henquin, JC; Nenquin, M | 1 |
| Frauman, AG; Moses, AC; Tramontano, D; Veneziani, BM | 1 |
| Bushfield, M; Johnson, RA; Shoshani, I; Stübner, D; Yeung, SM | 1 |
| Daval, JL; Deckert, J; Marangos, PJ; Redmond, DJ; Von Lubitz, DK | 1 |
| Mazurkiewicz, D; Saggerson, ED | 1 |
| Cushing, DJ; Mustafa, SJ; Sabouni, MH | 1 |
| Hara, M; Hirai, K; Matsuda, Y; Nakagawa, H; Okumura, N | 1 |
| Duman, RS; Enna, SJ; Strada, SJ | 1 |
| Fredholm, BB; Kvanta, A; Nordstedt, C; Van der Ploeg, I | 1 |
| Johnson, GV; Jope, RS; Li, XH | 1 |
| Anand-Srivastava, MB; Cantin, M; Gutkowska, J | 1 |
| Miledi, R; Woodward, RM | 1 |
| Fredholm, BB; Jondal, M; Kvanta, A; Nordstedt, C | 1 |
| Renit-Soria, J; Stinnakre, J; Van Renterghem, C | 1 |
| González-Nicolás, J; Jiménez, J; Moreno, FJ; Page-Pañuelas, A; Zabala, MT | 1 |
| Daval, JL; Deckert, J; Marangos, PJ; von Lubitz, DK | 1 |
| Bertrand, G; Bozem, M; Henquin, JC; Petit, P | 1 |
| Agarwal, KC; Maitra, RS; Zielinski, BA | 1 |
| Haraoka, S; Hina, K; Kusachi, S; Saito, D; Tsuji, T; Ueeda, M; Watanabe, H; Yamada, N | 1 |
| Cooke, BA; Dix, CJ; Habberfield, AD | 2 |
| Fredholm, BB; Lerner, UH; Sahlberg, K | 1 |
| Henrich, M; Piper, HM; Schrader, J | 1 |
| Fredholm, BB; Häggblad, J | 1 |
| Gonçalves, ML; Ribeiro, JA | 1 |
| Jacobson, B; Lerner, A; Miller, RA | 1 |
| Lowenstein, JM; Ravid, K | 1 |
| Behrman, HR; Musicki, B; Soodak, LK | 1 |
| Kammer, GM; Mitchell, E | 1 |
| Hearse, DJ; Mariani, M; Poddighe, R; Ronca, G; Zucchi, R | 1 |
| Dascal, N; Gelerstein, S; Oron, Y; Shapira, H; Yekuel, R | 1 |
| Chern, YJ; Kim, KT; Slakey, LL; Westhead, EW | 1 |
| Gniess, A; Reymann, A | 1 |
| Magistretti, PJ; Ofori, S; Schorderet, M | 1 |
| Enna, SJ; Karbon, EW; Shenolikar, S | 1 |
| Namoto, S | 1 |
| Baba, A; Iwata, H; Nishiuchi, Y; Tatsuno, T; Uemura, A | 1 |
| Freshney, RI; Pilkington, G; Vaughan, PF; Woods, MD | 1 |
| Deckert, J; Gleiter, CH; Marangos, PJ; Nutt, DJ | 1 |
| Parsons, WJ; Pierson, G; Stiles, GL; Sunay, S | 1 |
| Woodcock, EA | 1 |
| Malbon, CC; Mangano, TJ; Rapiejko, PJ | 1 |
| McCabe, J; Scholfield, CN | 1 |
| Gustafsson, LE; Hedqvist, P; Lundin, J; Wiklund, NP | 1 |
| Cooper, DM; Fossom, LH; Gill, DL; Owens, JR; Perez-Reyes, E; Yeung, SM | 1 |
| Davis, CW | 1 |
| Fredholm, BB; Li, YO | 1 |
| Burton, JL; Creveling, CR; Daly, JW; Hollingsworth, EB; McNeal, ET; Williams, RJ | 1 |
| Fredholm, BB; Jonzon, B; Nilsson, J | 1 |
| Hamburger-Bar, R; Newman, ME | 1 |
| Daly, JW; Hollingsworth, EB; Ukena, D | 1 |
| Anderson, RJ; Dillingham, MA | 1 |
| Fredholm, BB; Jonzon, B; Lindström, K | 2 |
| Fredholm, BB; Lindgren, E | 1 |
| Belardinelli, L; Isenberg, G; West, GA | 1 |
| Anand-Srivastava, MB; Cantin, M | 2 |
| Boehm, CA; Kammer, GM; Rudolph, SA | 1 |
| Kinnier, WJ; Marshall, RP; Noronha-Blob, L; U'Prichard, DC | 1 |
| Condorelli, M; Marone, G; Triggiani, M; Vigorita, S | 1 |
| Duman, RS; Enna, SJ | 1 |
| Jarett, L; Smith, JA; Wong, EH | 1 |
| Fredholm, BB; Nordstedt, C | 1 |
| Anand-Srivastava, MB; Cantin, M; Genest, J | 1 |
| Brown, SJ | 1 |
| Conti, M; Petrungaro, S; Salustri, A; Siracusa, G | 1 |
| Brun-Marmillon, J; Claustrat, B; Collin, JP; Falcón, J | 1 |
| Anand-Srivastava, MB | 2 |
| Edwards, BM; Ruoho, AE; Shanahan, MF | 1 |
| Schwartz, NB; Smalheiser, NR | 1 |
| Palmer, JM; Wood, JD; Zafirov, DH | 2 |
| Parsons, WJ; Stiles, GL | 1 |
| Kenakin, TP; Pike, NB | 1 |
| Griffin, MT; Law, PY; Loh, HH | 1 |
| Bugni, WJ; Kusachi, S; Olsson, RA | 1 |
| Block, T; Breckenridge, BM; Kon, C | 1 |
| Adnot, S; Ferry, N; Hanoune, J; Insel, PA | 1 |
| Baukal, A; Catt, KJ; Darbon, JM; Knecht, M; Ranta, T | 1 |
| Daly, JW; Sugio, K | 1 |
| Agarwal, KC; Parks, RE | 1 |
| Bertaccini, G; Coruzzi, G; Poli, E; Pozzoli, C | 1 |
| Hussain, T; Leigh, JH; Mustafa, SJ | 1 |
| Greger, R; Pavenstädt, H; Ruh, J; Schollmeyer, P | 1 |
| Craig, CG; Temple, SD; White, TD | 1 |
| Hume, JR; Levesque, PC | 1 |
| Harrison, PK; Kelly, E; Williams, RJ | 1 |
| Buchmüller-Rouiller, Y; Corradin, SB; Mauël, J; Ransijn, A | 1 |
| Borea, PA; Chiellini, G; Dalpiaz, A; Lucacchini, A; Martini, C; Varani, K | 1 |
| Abrahamsen, J; Nedergaard, OA | 1 |
| Cole, RL; Green, D; Grossbard, SJ; Hyman, SE; Konradi, C; Leveque, JC; Pollack, AE; Senatus, P | 1 |
| Challiss, RA; Morgan, AJ; Murray, KJ | 1 |
| Altiok, N; Fredholm, BB | 1 |
| Biden, TJ; Browne, CL | 1 |
| Akaike, N; Kawa, K; Uneyama, H; Yamashita, Y | 1 |
| Fischer, S; Karliczek, GF; Schaper, W; Sharma, HS | 1 |
| Arcelli, D; Borasio, PG; Fabbri, E; Ginanni-Corradini, F; Pavan, B; Poli, A | 1 |
| Berkich, DA; LaNoue, KF; Linden, J; Luthin, DR; Vannucci, SJ; Woodard, RL | 1 |
| Berg, KA; Clarke, WP; Maayani, S; McKay, R | 1 |
| Banerjee, A; Bensard, DD; Brew, EC; Fullerton, DA; Hahn, AR; McIntyre, RC | 1 |
| Friedman, M; Johnson, RG; Sellke, FW; Wang, SY; Weintraub, RM | 1 |
| Mita, M; Nagahama, Y; Yoshikuni, M | 1 |
| Schiele, JO; Schwabe, U | 1 |
| Correia-de-Sá, P; Ribeiro, JA | 2 |
| Alexander, SP; Curtis, AR; Hill, SJ; Kendall, DA | 1 |
| Barnabei, O; Lucchi, R; Poli, A; Traversa, U | 1 |
| Bohl, J; Lemmer, B; Ohm, T; Schnecko, A; Witte, K | 1 |
| Nakata, H; Saitoh, O; Saitoh, Y | 1 |
| Akatsuka, Y; Egashira, K; Katsuda, Y; Narishige, T; Shimokawa, H; Takeshita, A; Ueno, H | 1 |
| Désilets, M; Pucéat, M; Vassort, G | 1 |
| Alexander, SP; Cartmell, J; Kemp, JA; Kendall, DA; Shinozaki, H | 1 |
| Caciagli, F; Casabona, G; Ciccarelli, R; De Bernardis, E; Di Iorio, P; L'Episcopo, MR; Nicoletti, F; Shinozaki, H | 1 |
| Araki, T; Ban, H; Fujikura, H; Hasegawa, Y; Kato, H; Kogure, K | 1 |
| Christofi, FL; Wood, JD | 1 |
| Betteridge, DJ; Cooper, MB; Gasser, JA; Saggerson, ED; Tan, KC | 2 |
| Advenier, C; Brisac, AM; Cortijo, J; Laurent, S; Naline, E; Sarriá, B; Zhang, Y | 1 |
| Berg, KA; Chen, Y; Clarke, WP; Ebersole, BJ; Maayani, S; McKay, RD | 1 |
| Brookins, J; Fisher, JW; Ohigashi, T | 1 |
| Chern, Y; Fong, JC; Lai, HL; Liang, Y | 1 |
| Barajas-López, C | 1 |
| McGrath, JC; Smith, GC | 1 |
| Furukawa, T; Katsuragi, T; Ohba, M; Sato, C; Tokunaga, T | 1 |
| Baker, SP; Belardinelli, L; Olsson, RA; Shryock, J; Song, Y; Wang, D | 1 |
| Alexander, SP; Cartmell, J; Kemp, JA; Kendall, DA | 1 |
| Fiorella, D; Rabin, RA; Van Wylen, DG | 1 |
| Hussain, T; Mustafa, SJ | 1 |
| Chiba, S; Nakane, T | 1 |
| Boeynaems, JM; Côte, S; Van Sande, J | 1 |
| Alexander, SP; Cartmell, J; Curtis, AR; Kemp, JA; Kendall, DA | 1 |
| Chartrel, N; Lamacz, M; Tonon, MC; Vaudry, H | 1 |
| Gupta, RC; Neumann, J; Watanabe, AM | 1 |
| Domanska-Janik, K; Pyłowa, S; Zalewska, T | 1 |
| Ramírez, I; Soley, M; Tebar, F | 1 |
| Iizuka, H; Takahashi, H | 1 |
| Hashimoto, Y; Iizuka, H; Ishida-Yamamoto, A; Takahashi, H | 1 |
| Bottrill, FE; Hiley, CR; Richardson, PJ; Warnock, J | 1 |
| Collin, JP; Falcón, J; Van Camp, G | 1 |
| Aoki, Y; Hirano, D; Kodama, H; Nakamura, M; Ogasawara, H; Sakanaka, C; Shimizu, T; Waga, I | 1 |
| Chern, Y; Ching, YH; Lai, HL; Lee, EH; Lee, YC; Wang, HL | 1 |
| Benovic, JL; Palmer, TM; Stiles, GL | 1 |
| Schoepp, DD; Wright, RA | 1 |
| Gubitz, AK; Kirkpatrick, KA; Kurokawa, M; Richardson, PJ; Widdowson, L | 1 |
| Ahlberg, S; Fredholm, BB; Olsson, RA; Parkinson, FE; van der Ploeg, I | 1 |
| Akita, T; Joyner, RW; Kumar, R | 1 |
| Ingram, SL; Williams, JT | 1 |
| Li, Y; Rosenberg, PA | 1 |
| Figarella, C; Merten, M; Montserrat, C | 1 |
| Best, JA; Chen, Y; Nagamoto, K; Tank, AW | 1 |
| Andrés, A; Fernández, M; Ros, M; Sanz, JM; Vendite, D | 1 |
| Hastings, MH; McNulty, S; Morgan, PJ; Ross, AW; Shiu, KY | 1 |
| Burnstock, G; Höpker, VH; Saffrey, MJ | 1 |
| Baumann, R; Berghammer, M; Dragon, S; Glombitza, S; Pannermayr, M | 1 |
| Endou, H; Kurokawa, K; Miyanoshita, A; Nishi, T; Nosaka, K; Suzuki, K; Takahashi, T | 1 |
| Gidday, JM; Maceren, RG; Meier, JA; Shah, AR; Zhu, Y | 1 |
| Gysbers, JW; Rathbone, MP | 1 |
| Advenier, C; Dumas, JP; Dumas, M; Giudicelli, JF; Rochette, L | 1 |
| Fertel, RH; Wood, JD; Xia, Y | 1 |
| Dobson, JG; Ethier, MF | 1 |
| Bouritius, H; Groot, JA | 1 |
| Dar, MS | 1 |
| Friedman, E; Gao, E; Horwitz, J; Johnson, MD; Roberts, J; Snyder, DL | 1 |
| Belardinelli, L; Harrison, JK; Jacobson, M; Kollias-Baker, CA; Ozeck, M; Ruble, J; Shryock, JC | 1 |
| Miyata, M; Nishida, A; Shimizu, M; Yamawaki, S; Zensho, H | 1 |
| Nash, MS; Osborne, NN; Wood, JP | 1 |
| Chang, HY | 1 |
| Andrés, A; Cubero, A; Fernández, M; Gonzalez-Calero, G; Ros, M; Ruiz, A; Sanz, JM | 1 |
| Dukhanin, AS; Gubaeva, FR; Sergeev, PV | 1 |
| Chang, YH; Chern, Y; Ching, YH; Conti, M; Lai, HL; Lee, YC | 1 |
| Bauer, J; Fiebich, BL; Heese, K; Otten, U | 1 |
| Boyle, DL; Brinckerhoff, CE; Firestein, GS; Han, Z; Rutter, JL | 1 |
| Brundege, JM; Diao, L; Dunwiddie, TV; Proctor, WR | 1 |
| Fullerton, DA; McIntyre, RC; Meldrum, DR; Sheridan, BC | 1 |
| Bindels, RJ; Bouritius, H; Groot, JA; Hartog, A; Oprins, JC | 1 |
| Chen, Y; D'Angelo, G; Michel, JB; Pueyo, ME | 1 |
| Matthews, JB; Mun, EC; Tally, KJ | 1 |
| Lang, U; Vischer, UM; Wollheim, CB | 1 |
| Emeis, JJ; Hegeman, RJ; van den Eijnden-Schrauwen, Y | 1 |
| Dar, MS; Meng, ZH; Pennington, SN | 1 |
| Bobbin, RP; Chen, C | 1 |
| Bleich, M; Greger, R; Thiele, I; Warth, R | 1 |
| Glenn, JR; Heptinstall, S | 1 |
| Kimura, J; Matsuoka, I; Nakanishi, H; Ohkubo, S; Ono, T | 1 |
| Hill, RJ; Magee, W; Masamune, H; Oleynek, JJ; Tracey, WR | 1 |
| Bidet, M; Cuiller, B; Poujeol, C; Poujeol, P; Rubera, I; Tauc, M; Touret, N; Verheecke-Mauze, C | 1 |
| Florio, C; Frausin, F; Gaion, RM; Vertua, R | 2 |
| Arslan, G; Fredholm, BB; Kull, B | 1 |
| Ram, JL; Speyer, CL; Steffes, CP | 1 |
| Gean, PW; Lu, KT | 1 |
| Bagley, EE; Christie, MJ; Vaughan, CW | 1 |
| Bajnath, RB; Bouritius, H; Groot, JA | 1 |
| Habuchi, Y; Morikawa, J; Nishio, M; Tanaka, H; Yamamoto, T | 1 |
| Borgland, SL; Castañón, M; Parkinson, FE; Spevak, W | 1 |
| Delicado, EG; Miras-Portugal, MT; Sen, RP | 1 |
| Andrea Borea, P; Dalpiaz, A; IJzerman, AP; Pavan, B; Scatturin, A; Varani, K | 1 |
| Catalán, RE; Hernández, F; Martinez, AM | 1 |
| Frisbee, JC; Lombard, JH | 1 |
| Albert, JL; Anwar, Z; Boarder, MR; Boyle, JP; Gubby, SE; Roberts, JA; Webb, TE | 1 |
| Hsu, KS; Huang, CC; Liang, YC | 1 |
| Bouron, A | 1 |
| Friedman, E; Gao, E; Gao, F; Horwitz, J; Ma, XL; Pelleg, A; Snyder, DL; Xu, J | 1 |
| Dubey, RK; Gillespie, DG; Jackson, EK; Keller, PJ; Mi, Z; Rosselli, M | 1 |
| Hashimoto, K; Inoue, K; Lurie, KG; Shirai, T; Sugiyama, A | 1 |
| Battistini, B; Bernier, SG; Dubé, J; Gobeil, F; Guillemette, G; Pelletier, S; Sirois, P; Villeneuve, A | 1 |
| Behrsing, HP; Vulliet, PR | 1 |
| Gean, PW; Lu, KT; Wu, SP | 1 |
| Barth, H; Vischer, UM; Wollheim, CB | 1 |
| Araki, T; Imai, Y; Itoyama, Y; Kato, H; Mizugaki, M; Tanji, H | 1 |
| Neher, M; Petersen, N; Prinz, S; Sallmann, S; Schwaninger, M; Spranger, M | 1 |
| Heaps, CL; Laughlin, MH; Parker, JL; Rapps, JA; Sturek, M | 1 |
| Arslan, G; Fredholm, BB | 1 |
| Chang, HY; Chen, CW; Hsiue, TR | 1 |
| Holeton, D; Jia, LG; Linden, J; Taylor, AJ; Tucker, AL | 1 |
| Bagorda, A; Cardone, R; Casavola, V; Debellis, L; Guerra, L; Jacobson, KA; Li, AH; Reshkin, SJ | 1 |
| Frühbeck, G; Gómez-Ambrosi, J; Salvador, J | 1 |
| Kimura, J; Kumazawa, K; Matsuoka, I; Ohkubo, S; Sagawa, K | 1 |
| Hein, TW; Kuo, L; Muthuchamy, M; Wang, W; Zoghi, B | 1 |
| Pallone, TL; Silldorff, EP | 1 |
| Doering, A; Middlekauff, HR; Weiss, JN | 1 |
| Chern, Y; Huang, CL; Huang, NK; Lin, YW; Messing, RO | 1 |
| Gewirtz, AT; Madara, JL; Merlin, D; Si-Tahar, M; Sitaraman, SV; Wang, L; Wong, M | 1 |
| Dubey, RK; Gillespie, DG; Jackson, EK; Mi, Z | 1 |
| Carruthers, AM; Feniuk, W; Humphrey, PP; Jarvie, EM; Jenkins, DW; Sellers, LA | 1 |
| Combes, P; Crumiere, M; Dickenson, JM; Graham, S; Klotz, KN | 1 |
| Kim, KT; Kim, TD; Lee, JU; Seong, JK; Suh, BC | 1 |
| Kanoh, S; Kobayashi, H; Kondo, M; Motoyoshi, K; Nagai, A; Tamaoki, J | 1 |
| Benton, HP; Kollias-Baker, C; MacDonald, MH; Tesch, AM | 1 |
| Brundege, JM; Williams, JT | 1 |
| Mann, GE; Morgan, AJ; Pearson, JD; Sobrevia, L; Steinert, JR; Sugden, D; Wheeler-Jones, CP; Wyatt, AW | 1 |
| Alfinito, PD; Alli, R; Townes-Anderson, E | 1 |
| Barrière, H; Belfodil, R; Bidet, M; Poujeol, C; Poujeol, P; Rubera, I; Tauc, M | 2 |
| Erdmann, A; Gao, ZG; IJzerman, AP; Jacobson, KA; Kim, SG; Melman, N; Müller, CE | 1 |
| Boehm, S; Freissmuth, M; Just, H; Klinger, M; Korkhov, VM; Kudlacek, O; Nanoff, C; Pankevych, H; Vartian, N; Yang, Q | 1 |
| Blay, J; Butler, JJ; Hoskin, DW; Mader, JS; Watson, CL; Zhang, H | 1 |
| Christie, MJ; Hack, SP; Vaughan, CW | 1 |
| Häussinger, D; Reinehr, R | 1 |
| Albasanz, JL; Fernández, M; León, D; Martín, M; Ruíz, MA | 1 |
| Karami-Tehrani, F; Panjehpour, M | 1 |
| Fujita, T; Kumamoto, E; Yang, K | 1 |
| Anfossi, G; De Salve, A; Doronzo, G; Mattiello, L; Russo, I; Trovati, M | 1 |
| Huwiler, A; Pfeilschifter, J; Ren, S; Xin, C | 1 |
| Chemtob, S; Clyman, RI; Fouron, JC; Ginzinger, D; Kajino, H; Marrache, AM; Moss, TJ; Roman, C; Seidner, SR; Vazquez-Tello, A; Waleh, N | 1 |
| Carey, GB; Goodman, JM; Overman, KC; Reineck, KE; Wotjukiewicz, LJ | 1 |
| Boehm, S; Dorostkar, MM; Edelbauer, H; Lechner, SG; Mayer, M; Pankevych, H | 1 |
| Brummer, T; Huber, M; Minguet, S; Reth, M; Rosenkranz, L; Schamel, WW | 1 |
| de Ligt, RA; IJzerman, AP; Leurs, R; Lorenzen, A; Rivkees, SA | 1 |
| Kamiya, T; Nakata, H; Saitoh, O | 1 |
| Braasch, DA; Buddington, RK; Kimura, Y; Turner, JR | 1 |
| Conrad, DM; El-Darahali, A; Fawcett, H; Hoskin, DW; Mader, JS | 1 |
| Demarest, KT; Tang, Y | 1 |
| Birabil, CG; Marks, GA; Speciale, SG | 1 |
| Chen, JF; Cunha, RA; Domenici, MR; Grò, MC; Martire, A; Pepponi, R; Popoli, P; Rebola, N; Schwarzschild, MA; Tebano, MT | 1 |
| Cao, C; Han, JH; Kim, SH; Kim, SZ; Yuan, K | 1 |
| Aceves, J; Erlij, D; Florán, B; Florán, L; Gonzalez, B; Paz, F | 1 |
| Hashimoto, N; Iida-Tanaka, N; Ishimaru, S; Ito, M; Matsuda, T; Saito, T; Shigenobu, K; Tanaka, H; Tsuruoka, N; Tsuruzoe, N; Yamashita, T | 1 |
| D'hondt, C; Himpens, B; Srinivas, SP; Vereecke, J | 1 |
| Drmota, T; Hermansson, NO; Larsson, N; Morgan, DG | 1 |
| Adams, DJ; Bartlett, PF; Stafford, MR | 1 |
| Benton, HP; Russell, JM; Stephenson, GS; Yellowley, CE | 1 |
| Albasanz, JL; Ferrer, I; Martín, M; Rodríguez, A | 1 |
| Aerbajinai, W; Bhanu, NV; Gantt, NM; Lee, YT; Miller, JL; Noel, P; Oneal, PA; Thomas, CJ | 1 |
| Borea, PA; Cadossi, R; Caruso, A; De Mattei, M; Fini, M; Masieri, FF; Ongaro, A; Pellati, A; Varani, K; Vincenzi, F | 1 |
| Bowles, DK; Heaps, CL; Jeffery, EC; Laine, GA; Price, EM | 1 |
| Dumas, A; Dussault, AA; Laflamme, C; Michaud, A; Pouliot, M; St-Onge, M | 1 |
| Chinn, M; Choe, SA; Choi, WJ; Gao, ZG; Heller, CL; Hou, X; Jacobson, KA; Jeong, LS; Kim, HO; Lee, SK; Pal, S | 1 |
| Hanada, M; Ishii, K; Mori, A; Nakahara, T; Saigo, O | 1 |
| Albasanz, JL; Castillo, CA; León, DA; Martín, M | 1 |
| Dubey, RK; Gillespie, DG; Jackson, EK; Mi, Z; Rosselli, M | 1 |
| Bernascone, S; Distasi, C; Erriquez, J; Ferraro, M; Genazzani, AA | 1 |
| Shivanna, M; Srinivas, SP | 1 |
| Dobson, JG; Fenton, RA; Ikebe, M; Komatsu, S; Shea, LG | 1 |
| Frye, SV; Hull-Ryde, EA; Janzen, WP; Jin, J; Korboukh, I; Rittiner, JE; Zylka, MJ | 1 |
| Duarte, T; Godinho, RO; Menezes-Rodrigues, FS | 1 |
| Novak, I; Wang, J | 1 |
| Gartner, TK; Li, Z; Morris, AJ; Ren, H; Smyth, SS; Sunkara, M; Xiang, B; Zhang, G | 1 |
| Nairn, AC; Palfrey, C; Shimizu, Y; Wiseman, SL | 1 |
| Bond, M; Cui, MZ; Duggirala, A; Hewer, RC; Hindmarch, CC; Kimura, TE; Newby, AC | 1 |
| Baqi, Y; Hoffmann, K; Lutz, DA; Müller, CE; Straßburger, J; von Kügelgen, I | 1 |
| Cascalheira, JF; Sebastião, AM; Serpa, A | 1 |
| Bond, M; Duggirala, A; Johnson, JL; Kimura, TE; Newby, AC; Sala-Newby, GB; Wu, YJ | 1 |
| Cascalheira, JF; Correia, S; Ribeiro, JA; Sebastião, AM; Serpa, A | 1 |
| Briddon, SJ; Hill, SJ; Kellam, B; Stoddart, LA; Vernall, AJ | 1 |
| Fernández-Fernández, D; Kroker, KS; Rosenbrock, H | 1 |
| Aungraheeta, R; Butler, M; Conibear, A; Kelly, E; Mumford, A; Mundell, SJ; Nylander, S | 1 |
| An, JR; An, TG; Ha, KS; Han, ET; Hong, SH; Jeon, J; Kim, J; Lee, JM; Lee, SJ; Li, H; Na, SH; Park, WS; Seo, MS; Shin, SE; Yim, MJ | 1 |
| Dev, K; Hynes, AC; Keating, N; Quinlan, LR | 1 |
| Alves-Do-Prado, W; Ambiel, CR; Castellão-Santana, LM; Correia-de-Sá, P; Noronha-Matos, JB; Peixoto, AR; Yumi Abiko, P | 1 |
| Andrews, RK; Clark, JC; Gardiner, EE; Hill, SJ; Kavanagh, DM; Pike, JA; Poulter, NS; Watson, S; Watson, SP | 1 |
| Bertoldo, MJ; Bustamante, S; Gilchrist, RB; Kanakkaparambil, R; Lavea, CF; Richani, D; Riepsamen, AH | 1 |
| Bai, K; Gu, C; Guo, F; Li, J; Mao, L; Nielsen, AV; Tang, C; Wu, Q; Xu, X; Yang, Z; Ye, C; Ye, J; Zhao, Y | 1 |
| Hao, JW; Hu, WP; Li, Q; Li, XM; Liu, TT; Qiao, WL; Qiu, CY; Wei, S | 1 |
1 review(s) available for adenosine and colforsin
| Article | Year |
|---|---|
[The adenylate cyclase system of human platelets].
Topics: Adenosine; Adenosine Triphosphate; Adenylyl Cyclases; Adrenergic beta-Agonists; Blood Platelets; Cell Membrane; Chemical Phenomena; Chemistry; Colforsin; Cyclic AMP; Diterpenes; Enzyme Activation; Ethylmaleimide; Fluorine; Humans; Membrane Proteins; Peptide Hydrolases; Platelet Aggregation; Prostaglandins; Protein Conformation; Receptors, Adrenergic, alpha; Receptors, Cell Surface | 1983 |
376 other study(ies) available for adenosine and colforsin
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Forskolin stimulation of cyclic AMP accumulation in rat brain cortex slices is markedly enhanced by endogenous adenosine.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Cerebral Cortex; Colforsin; Cyclic AMP; Drug Synergism; In Vitro Techniques; Male; Phosphodiesterase Inhibitors; Purinergic Antagonists; Rats; Rats, Inbred Strains | 1992 |
Purinergic receptor activation of Cl- secretion in T84 cells.
Topics: Adenosine; Adenosine Triphosphate; Calcium; Chlorides; Colforsin; Colonic Neoplasms; Cyclic AMP; Humans; Nucleotides; Pertussis Toxin; Receptors, Purinergic; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1992 |
Effects of forskolin, dibutyryl cyclic AMP, and 5'-N-ethylcarboxamide adenosine on 22Na uptake by rat brain synaptosomes stimulated by veratridine.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Brain; Bucladesine; Colforsin; Rats; Sodium; Sodium Radioisotopes; Synaptosomes; Veratridine | 1992 |
Competitive regulation of phospholipase C responses by cAMP and calcium.
Topics: Adenosine; Calcium; Calcium Channel Blockers; Cell Line; Chelating Agents; Colforsin; Cyclic AMP; Enzyme Activation; Fura-2; Hydrolysis; Inositol Phosphates; Norepinephrine; Phosphatidylinositols; Type C Phospholipases | 1992 |
Forskolin effects on slow inward current and phasic tension of frog atrial fibres: modulation by adenosine and phosphodiesterase inhibitors.
Topics: Adenosine; Animals; Calcium Channels; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Electric Stimulation; Heart Atria; In Vitro Techniques; Myocardial Contraction; Phosphodiesterase Inhibitors; Propranolol; Rana esculenta; Rana ridibunda; Stimulation, Chemical | 1992 |
Effect of adenosine A1 and A2 agonists and antagonists on cAMP and Ca2+ in cultured rat mesangial cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Glomerular Mesangium; Purines; Rats; Sulfonamides; Xanthines | 1992 |
A2-adenosine receptor stimulation increases macromolecule permeability of coronary endothelial cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Capillary Permeability; Cells, Cultured; Colforsin; Coronary Vessels; Cyclic AMP; Endothelium, Vascular; Energy Metabolism; Isoproterenol; Macromolecular Substances; Microscopy, Electron, Scanning; Receptors, Purinergic | 1992 |
Mediation of serotonin hyperalgesia by the cAMP second messenger system.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenosine; Analgesics; Animals; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Guanosine 5'-O-(3-Thiotriphosphate); Hyperalgesia; Isomerism; Male; Nociceptors; Pain; Protein Kinase Inhibitors; Pyrrolidines; Pyrrolidinones; Rats; Rats, Inbred Strains; Receptors, Serotonin; Rolipram; Second Messenger Systems; Serotonin; Tetrahydronaphthalenes | 1992 |
Non-eicosanoid functions of essential fatty acids: regulation of adenosine-related functions in cultured neuroblastoma cells.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Deaminase; Animals; Calcium; Colforsin; Cyclic AMP; Eicosanoids; Fatty Acids, Essential; Fatty Acids, Unsaturated; Neuroblastoma; Receptors, Purinergic; Theophylline; Tumor Cells, Cultured | 1992 |
ATP and its metabolite adenosine act synergistically to mobilize intracellular calcium via the formation of inositol 1,4,5-trisphosphate in a smooth muscle cell line.
Topics: Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Calcium; Cell Line; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Inositol 1,4,5-Trisphosphate; Kinetics; Leiomyosarcoma; Muscle, Smooth; Pertussis Toxin; Purinergic Antagonists; Receptors, Purinergic; Theophylline; Type C Phospholipases; Virulence Factors, Bordetella | 1992 |
Rapid oxygen-dependent changes in erythropoietin mRNA in perfused rat kidneys: evidence against mediation by cAMP.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Albuterol; Animals; Bucladesine; Colforsin; Cyclic AMP; Erythropoietin; Hypoxia; In Vitro Techniques; Kidney; Male; Oxygen; Perfusion; Rats; Rats, Inbred Strains; RNA, Messenger | 1992 |
Stimulation of adenosine A1 receptors and bradykinin receptors, which act via different G proteins, synergistically raises inositol 1,4,5-trisphosphate and intracellular free calcium in DDT1 MF-2 smooth muscle cells.
Topics: Adenosine; Animals; Bradykinin; Calcium; Cell Line; Colforsin; Cricetinae; Drug Synergism; Egtazic Acid; GTP-Binding Proteins; Inositol 1,4,5-Trisphosphate; Kinetics; Leiomyosarcoma; Mesocricetus; Muscle, Smooth; Pertussis Toxin; Receptors, Bradykinin; Receptors, Neurotransmitter; Receptors, Purinergic; Virulence Factors, Bordetella | 1992 |
Adenosine receptors on human airway epithelia and their relationship to chloride secretion.
Topics: Adenosine; Aminophylline; Calcium; Cells, Cultured; Chlorides; Colforsin; Cyclic AMP; Epithelium; Humans; Receptors, Purinergic; Respiratory System; Tritium | 1992 |
cAMP production via the adenylyl cyclase pathway is reduced in RCS rat RPE.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Disease Models, Animal; Pigment Epithelium of Eye; Prostaglandins E; Rats; Rats, Mutant Strains; Receptors, Prostaglandin; Receptors, Purinergic; Retinal Degeneration; Signal Transduction; Vasodilator Agents | 1992 |
Functional localization of adenosine receptor-mediated pathways in the LLC-PK1 renal cell line.
Topics: Adenosine; Calcium; Cell Line; Colforsin; Cyclic AMP; Inositol Phosphates; Intracellular Membranes; Kidney; Receptors, Purinergic; Signal Transduction; Time Factors; Tissue Distribution; Xanthines | 1992 |
Regulation of neurosecretory habituation in PC12 cells: parallel pathways used by cAMP and calcium.
Topics: Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Calcium; Colforsin; Cyclic AMP; Habituation, Psychophysiologic; Kinetics; Memory; Models, Neurological; Neurons; Norepinephrine; PC12 Cells; Time Factors | 1992 |
RFL9 encodes an A2b-adenosine receptor.
Topics: Adenosine; Amino Acid Sequence; Animals; Brain; CHO Cells; Cloning, Molecular; Colforsin; Cricetinae; Cyclic AMP; DNA; Gene Expression; Kinetics; Molecular Sequence Data; Protein Conformation; Rats; Receptors, Purinergic; RNA, Messenger; Transfection | 1992 |
Further studies of the mechanism(s) of polyunsaturated-fatty-acid-mediated increases in intracellular cAMP formation in N1E-115 neuroblastoma cells.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 5'-Nucleotidase; Adenosine; Basal Metabolism; Colforsin; Cyclic AMP; Dipyridamole; Linoleic Acid; Linoleic Acids; Neuroblastoma; Neurons; Pentostatin; Receptors, Purinergic; Tumor Cells, Cultured | 1992 |
Increases in endothelial cyclic AMP levels amplify agonist-induced formation of endothelium-derived relaxing factor (EDRF).
Topics: Adenosine; Adenosine Triphosphate; Animals; Bradykinin; Calcimycin; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Endothelium, Vascular; Ethers, Cyclic; In Vitro Techniques; Isoproterenol; Isoquinolines; Nitric Oxide; Nitroprusside; Okadaic Acid; Protein Kinases; Swine | 1992 |
Adenylate cyclase induces intracellular calcium increase in single human epidermal keratinocytes measured by fluorescence microscopy using Fura 2-AM.
Topics: Adenosine; Adenylyl Cyclases; Bucladesine; Calcium; Cells, Cultured; Colforsin; Epinephrine; Fluorescent Dyes; Fura-2; Histamine; Humans; Intracellular Fluid; Keratinocytes; Microscopy, Fluorescence | 1992 |
Adenosine receptors, cyclic AMP accumulation, and DNA-synthesis in aortic smooth muscle cell cultures of adult and neonatal rats.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Aging; Animals; Aorta; Cells, Cultured; Colforsin; Cyclic AMP; DNA; Muscle, Smooth, Vascular; Phenylisopropyladenosine; Rats; Rats, Sprague-Dawley; Receptors, Purinergic | 1992 |
Effect of adenosine analogues and cAMP-raising agents on TNF-, GM-CSF-, and chemotactic peptide-induced degranulation in single adherent neutrophils.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Blood Proteins; Bucladesine; Cell Adhesion; Cell Degranulation; Chemotactic Factors; Colforsin; Cyclic AMP; Cytochalasin B; Exocytosis; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1992 |
Cloning and functional characterization of a human A1 adenosine receptor.
Topics: Adenosine; Amino Acid Sequence; Animals; Base Sequence; CHO Cells; Cloning, Molecular; Colforsin; Cricetinae; DNA; DNA Probes; Dogs; Hippocampus; Humans; Molecular Sequence Data; Nucleic Acid Hybridization; Receptors, Purinergic; Sequence Homology, Nucleic Acid; Transfection; Xanthines | 1992 |
Adenosine-sensitive afterdepolarizations and triggered activity in guinea pig ventricular myocytes.
Topics: Action Potentials; Adenosine; Animals; Arrhythmias, Cardiac; Colforsin; Dideoxyadenosine; Female; Guinea Pigs; Heart Conduction System; Heart Ventricles; In Vitro Techniques; Isoproterenol; Male; Membrane Potentials; Quinidine; Receptors, Purinergic; Ventricular Function | 1992 |
Vasomotor properties of porcine endocardial and epicardial microvessels.
Topics: Adenosine; Animals; Colforsin; Coronary Circulation; Endocardium; Endothelium, Vascular; Microcirculation; Nitroprusside; Pericardium; Swine; Vasomotor System | 1992 |
Isolation and characterization of a novel cardiac adenylylcyclase cDNA.
Topics: Adenosine; Adenylyl Cyclases; Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Calcium; Cattle; Colforsin; DNA; Dogs; Enzyme Activation; Guanosine 5'-O-(3-Thiotriphosphate); Mice; Molecular Sequence Data; Myocardium; Open Reading Frames; Rats; Restriction Mapping; RNA, Messenger; Sodium Fluoride | 1992 |
Desensitization of the epidermal adenylate cyclase system: agonists and phorbol esters desensitize by independent mechanisms.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Adenosine Triphosphate; Adenylate Cyclase Toxin; Adenylyl Cyclases; Alkaloids; Animals; Cholera Toxin; Colforsin; Cyclic AMP; Epidermis; Epinephrine; Histamine; Isoquinolines; Pertussis Toxin; Piperazines; Receptors, Adrenergic, beta; Receptors, Histamine; Skin; Staurosporine; Swine; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1991 |
The orphan receptor cDNA RDC7 encodes an A1 adenosine receptor.
Topics: Adenosine; Animals; Brain; Cell Line; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; DNA; Dogs; GTP-Binding Proteins; Male; Receptors, Cell Surface; Receptors, Purinergic; Receptors, Purinergic P1; Recombinant Proteins; Testis; Thyroid Gland; Tissue Distribution | 1991 |
Autoradiographic analysis of second messenger and neurotransmitter system receptors in the gerbil hippocampus following transient forebrain ischemia.
Topics: Adenosine; Adenylyl Cyclases; Animals; Autoradiography; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Colforsin; Gerbillinae; Hippocampus; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Ischemic Attack, Transient; Isradipine; Male; Neurons; Organ Specificity; Oxadiazoles; Phorbol 12,13-Dibutyrate; Protein Kinase C; Pyramidal Tracts; Quinuclidinyl Benzilate; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Muscarinic; Receptors, Purinergic; Second Messenger Systems; Time Factors; Tritium | 1991 |
Elevated extracellular glucose inhibits an adenosine-(Na+,K+)-ATPase regulatory system in rabbit aortic wall.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Aorta, Thoracic; Child, Preschool; Colforsin; Diglycerides; Glucose; Glycerol; Homeostasis; Humans; In Vitro Techniques; Inositol; Male; Muscle, Smooth, Vascular; Phosphatidylinositols; Potassium; Rubidium; Sodium-Potassium-Exchanging ATPase; Theophylline | 1991 |
Attenuated adenosine-sensitivity and decreased adenosine-receptor number in adipocyte plasma membranes in human obesity.
Topics: Adenosine; Adenylyl Cyclases; Adipose Tissue; Body Weight; Cell Membrane; Colforsin; Cyclic AMP; Enzyme Activation; Glucose; Humans; Isoproterenol; Obesity; Phenylisopropyladenosine; Receptors, Purinergic; Xanthines | 1991 |
Endogenous adenosine inhibits platelet aggregation during myocardial ischemia in dogs.
Topics: Adenosine; Animals; Blood Pressure; Bucladesine; Colforsin; Coronary Circulation; Coronary Disease; Dogs; Platelet Activation; Platelet Aggregation; Theophylline | 1991 |
Inhibition of adenylate cyclase attenuates adenosine receptor-mediated relaxation in coronary artery.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Animals; Colforsin; Coronary Vessels; Cyclic AMP; Dideoxyadenosine; Dilazep; Guanosine Triphosphate; In Vitro Techniques; Muscle Relaxation; Receptors, Purinergic; Sodium Fluoride; Swine; Vasodilator Agents | 1991 |
Identification of cyclic AMP as the response regulator for neurosecretory potentiation: a memory model system.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Bucladesine; Cell Line; Colforsin; Cyclic AMP; Epinephrine; Memory; Models, Neurological; Models, Psychological; Neurons; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Cell Surface; Receptors, Dopamine; Receptors, Purinergic; Receptors, Serotonin | 1991 |
Collagen-induced exposure of anionic phospholipid in platelets and platelet-derived microparticles.
Topics: 4-Chloromercuribenzenesulfonate; Adenosine; Affinity Labels; Alkaloids; Anions; Annexin A5; Binding Sites; Blood Platelets; Bucladesine; Calcimycin; Calcium-Binding Proteins; Colforsin; Collagen; Cyclic GMP; Factor Va; Flow Cytometry; Humans; Nitroprusside; Phospholipids; Platelet Aggregation; Pregnancy Proteins; Signal Transduction; Staurosporine; Theophylline; Thromboplastin | 1991 |
Characterization of the glycogenolysis elicited by vasoactive intestinal peptide, noradrenaline and adenosine in primary cultures of mouse cerebral cortical astrocytes.
Topics: Adenosine; Animals; Astrocytes; Bucladesine; Cells, Cultured; Cerebral Cortex; Colforsin; Energy Metabolism; Glycogen; Mice; Norepinephrine; Phorbol 12,13-Dibutyrate; Vasoactive Intestinal Peptide | 1991 |
Adenosine-dependent regulation of cyclic AMP accumulation in primary cultures of rat astrocytes and neurons.
Topics: Adenosine; Animals; Astrocytes; Cells, Cultured; Colforsin; Cyclic AMP; Neurons; Rats | 1991 |
CD3-dependent increase in cyclic AMP in human T-cells following stimulation of the CD2 receptor.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; CD2 Antigens; CD3 Complex; Cell Line; Colforsin; Cyclic AMP; Humans; Prostaglandin Antagonists; Receptors, Antigen, T-Cell; Receptors, Immunologic; T-Lymphocytes; Type C Phospholipases; Vasodilator Agents | 1991 |
Adenosine receptor-mediated accumulation of cyclic AMP-induced T-lymphocyte death through internucleosomal DNA cleavage.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Bucladesine; Cell Survival; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Kinetics; Male; Mice; Mice, Inbred BALB C; Phenylisopropyladenosine; Receptors, Purinergic; T-Lymphocytes | 1990 |
NaF and guanine nucleotides modulate adenylate cyclase activity in NG108-15 cells by interacting with both Gs and Gi.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Cell Membrane; Colforsin; Enzyme Activation; Epoprostenol; GTP-Binding Proteins; Guanine Nucleotides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Iloprost; Mice; Morphine; Nervous System Neoplasms; Neuroblastoma; Pertussis Toxin; Sodium Fluoride; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1990 |
Xenopus oocyte K+ current. III. Phorbol esters and pH regulate current at gap junctions.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Colforsin; Cyclic AMP; Female; Follicle Stimulating Hormone; Hydrogen-Ion Concentration; Intercellular Junctions; Isoproterenol; Kinetics; Mathematics; Models, Biological; Oocytes; Phorbol 12,13-Dibutyrate; Potassium Channels; Xenopus laevis | 1990 |
Two mechanisms of inhibition by prostaglandin E2 of hormone-dependent cell cAMP in the rat collecting tubule.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Animals; Arginine Vasopressin; Colforsin; Cyclic AMP; Dinoprostone; Indomethacin; Isoproterenol; Kidney Tubules, Collecting; Male; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Signal Transduction; Xanthines | 1990 |
Carbachol enhances forskolin-stimulated cyclic AMP accumulation via activation of calmodulin system in human neuroblastoma SH-SY5Y cells.
Topics: Adenosine; Alprostadil; Atropine; Calmodulin; Carbachol; Cell Line; Colforsin; Cyclic AMP; Drug Synergism; Humans; Kinetics; Naphthalenes; Neuroblastoma; Pertussis Toxin; Polycyclic Compounds; Protein Kinase C; Trifluoperazine; Vasoactive Intestinal Peptide; Virulence Factors, Bordetella | 1991 |
Involvement of lipid peroxidation and inhibitory mechanisms on ischemic neuronal damage in gerbil hippocampus: quantitative autoradiographic studies on second messenger and neurotransmitter systems.
Topics: Adenosine; Animals; Autoradiography; Body Temperature; Brain Ischemia; Calcium Channels; Chlorides; Colforsin; Gerbillinae; Hippocampus; Inositol 1,4,5-Trisphosphate; Ion Channels; Lipid Peroxidation; Male; Neurons; Neurotransmitter Agents; Pentobarbital; Phorbol 12,13-Dibutyrate; Quinazolines; Quinuclidinyl Benzilate; Receptors, GABA-A; Second Messenger Systems | 1991 |
Forskolin and phosphodiesterase inhibitors release adenosine but inhibit morphine-evoked release of adenosine from spinal cord synaptosomes.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 5'-Nucleotidase; Adenosine; Animals; Colforsin; Cyclic AMP; In Vitro Techniques; Morphine; Phosphodiesterase Inhibitors; Pyrrolidinones; Rats; Rolipram; Spinal Cord; Synaptosomes | 1991 |
Further confirmation of the role of adenyl cyclase and of cAMP-dependent protein kinase in primary afferent hyperalgesia.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Dinoprostone; Epoprostenol; Hyperalgesia; Male; Phosphorylation; Protein Kinases; Pyrrolidinones; Rats; Rats, Inbred Strains; Rolipram; Second Messenger Systems; Sensory Thresholds; Thionucleotides | 1991 |
Endogenous adenosine is an autacoid feedback inhibitor of chloride transport in the shark rectal gland.
Topics: Adenosine; Adenosine Deaminase; Animals; Biological Transport; Chlorides; Colforsin; Dogfish; Feedback; In Vitro Techniques; Inosine; Male; Salt Gland; Theophylline; Thioinosine | 1991 |
Adenosine A1 and non-A1 receptors: intracellular analysis of the actions of adenosine agonists and antagonists in rat hippocampal neurons.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Colforsin; Electric Stimulation; Electrodes; Hippocampus; Male; Membrane Potentials; Neurons; Phenylisopropyladenosine; Purinergic Antagonists; Rats; Rats, Inbred Strains; Receptors, Purinergic; Synapses; Theophylline; Xanthines | 1991 |
Vascular responses of umbilical-placental circulation to vasodilators in fetal lambs.
Topics: Adenosine; Animals; Blood Pressure; Colforsin; Epoprostenol; Fetus; Nitroglycerin; Placenta; Regional Blood Flow; Sheep; Umbilical Cord; Vascular Resistance; Vasodilator Agents | 1991 |
Arterial adaptations to altered blood flow.
Topics: Adaptation, Physiological; Adenosine; Animals; Arteries; Blood Circulation; Blood Pressure; Carotid Arteries; Colforsin; Male; Nitroprusside; Perfusion; Rabbits | 1991 |
The interaction of adenosine analogues with cAMP-generating and cAMP-independent positive inotropic agents in rabbit left atrium.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylate Cyclase Toxin; Animals; Cardiotonic Agents; Colforsin; Cyclic AMP; Drug Interactions; Female; Heart Atria; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Pertussis Toxin; Phenylephrine; Phenylisopropyladenosine; Potassium Channels; Rabbits; Receptors, Purinergic; Virulence Factors, Bordetella | 1990 |
Extracellular ATP shows synergistic enhancement of DNA synthesis when combined with agents that are active in wound healing or as neurotransmitters.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Imidodiphosphate; Animals; Cells, Cultured; Cholera Toxin; Colforsin; DNA; DNA Replication; Drug Synergism; Epidermal Growth Factor; Insulin; Keratinocytes; Kinetics; Mice; Mice, Inbred BALB C; Neurotransmitter Agents; Platelet-Derived Growth Factor; Thymidine; Transforming Growth Factors; Tritium; Vasoactive Intestinal Peptide; Wound Healing | 1990 |
Activation of adenosine A1 receptor by N6-(R)-phenylisopropyladenosine (R-PIA) inhibits forskolin-stimulated tyrosine hydroxylase activity in rat striatal synaptosomes.
Topics: Adenosine; Animals; Colforsin; Corpus Striatum; Male; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Synaptosomes; Tyrosine 3-Monooxygenase | 1990 |
A1 adenosine receptors inhibit chloride transport in the shark rectal gland. Dissociation of inhibition and cyclic AMP.
Topics: 2-Chloroadenosine; Adenosine; Adenylyl Cyclases; Animals; Chlorides; Colforsin; Cyclic AMP; Dogfish; Female; In Vitro Techniques; Kinetics; Male; Perfusion; Receptors, Purinergic; Salt Gland; Somatostatin; Theophylline | 1990 |
Adenosine A2 stimulation of tyrosine hydroxylase in rat striatal minces is reversed by dopamine D2 autoreceptor activation.
Topics: 2-Chloroadenosine; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Animals; Apomorphine; Colforsin; Corpus Striatum; Cyclic AMP; Dopamine Agents; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Purinergic; Theophylline; Tyrosine 3-Monooxygenase | 1990 |
Effects of topical adenosine analogs and forskolin on rat pial arterioles in vivo.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Arterioles; Colforsin; Male; Phenylisopropyladenosine; Pia Mater; Rats; Rats, Inbred Strains; Vasodilation | 1991 |
Adenylate cyclase induces intracellular Ca2+ increase in single human epidermal keratinocytes of the epidermal sheet as measured by digital imaging microscopy using Fura 2-AM.
Topics: Adenosine; Adenylyl Cyclases; Albuterol; Calcium; Cells, Cultured; Colforsin; Epinephrine; Fura-2; Histamine; Humans; Keratinocytes; Microscopy, Fluorescence; Propranolol | 1991 |
Late ontogenetic development of adenosine A1 receptor coupling to associated G-proteins in guinea pig cerebellum but not forebrain.
Topics: Adenosine; Adenylyl Cyclases; Animals; Cerebellum; Colforsin; Female; GTP-Binding Proteins; Guanosine Diphosphate; Guinea Pigs; Pregnancy; Receptors, Purinergic | 1990 |
Interactions between adenosine and phorbol esters or lithium at the frog neuromuscular junction.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Adenylyl Cyclases; Animals; Colforsin; Enzyme Activation; Evoked Potentials; Imines; Isoquinolines; Lithium; Muscles; Neuromuscular Junction; Phorbol Esters; Piperazines; Polymyxin B; Protein Kinase C; Rana ridibunda; Synaptic Transmission | 1990 |
12-O-tetradecanoylphorbol 13-acetate potentiates the action of cAMP in inducing DNA cleavage in thymocytes.
Topics: 2-Chloroadenosine; Adenosine; Animals; Bucladesine; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; DNA; Kinetics; Male; Mice; Mice, Inbred BALB C; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1990 |
Adenosine 3',5'-cyclic monophosphate enhances dopamine accumulation in rat hypothalamic cell culture containing dopaminergic neurons.
Topics: Adenosine; Animals; Animals, Newborn; Bucladesine; Butyrates; Butyric Acid; Cells, Cultured; Colforsin; Cyclic AMP; Dopamine; Female; Hypothalamus; Kinetics; Male; Neurons; Rats; Rats, Inbred Strains; Sodium Chloride; Tritium | 1990 |
Interaction of adenosine with vasopressin in the inner medullary collecting duct.
Topics: Adenosine; Animals; Arginine Vasopressin; Colforsin; Culture Techniques; Cyclic AMP; Diuresis; Drug Interactions; Kidney Medulla; Kidney Tubules, Collecting; Male; Pertussis Toxin; Rats; Rats, Inbred Strains; Virulence Factors, Bordetella | 1990 |
Adenylate cyclase system in fetal rat keratinizing epidermal cells (FRSK cells) and SV40-transformed human keratinocytes.
Topics: Adenosine; Adenylyl Cyclases; Animals; Blotting, Northern; Cell Line; Cell Line, Transformed; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Epinephrine; Histamine; Humans; Keratinocytes; Rats; RNA, Messenger; Simian virus 40 | 1990 |
Is adenosine involved in inhibition of forskolin-stimulated cyclic AMP accumulation by caffeine in rat brain?
Topics: Adenosine; Adenosine Deaminase; Animals; Brain Chemistry; Caffeine; Cerebral Cortex; Colforsin; Cyclic AMP; Dipyridamole; Drug Synergism; In Vitro Techniques; Male; Phosphodiesterase Inhibitors; Potassium Chloride; Rats; Rats, Inbred Strains; Receptors, Purinergic | 1990 |
Xenopus oocyte K+ current. II. Adenylyl cyclase-linked receptors on follicle cells.
Topics: Adenosine; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Female; Follicle Stimulating Hormone; Kinetics; Oocytes; Potassium Channels; Receptors, Cell Surface; Receptors, Purinergic; Xenopus laevis | 1990 |
Dual modulation by adenosine of gastrin release from canine G-cells in primary culture.
Topics: Adenosine; Animals; Bombesin; Cells, Cultured; Colforsin; Dogs; Gastric Mucosa; Gastrins; Kinetics; Phenylisopropyladenosine; Receptors, Purinergic | 1990 |
Adenosine A1 receptor-mediated inhibition of surfactant secretion in rat type II pneumocytes.
Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Cells, Cultured; Choline; Colforsin; Diglycerides; Ionomycin; Kinetics; Lung; Male; Phosphatidylcholines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Terbutaline; Tetradecanoylphorbol Acetate | 1990 |
Effect of 5'-(N-ethylcarboxamido)adenosine on adenosine transport in cultured chromaffin cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Affinity Labels; Animals; Biological Transport; Cells, Cultured; Chromaffin System; Colforsin; Dipyridamole; Kinetics; Nucleosides; Receptors, Purinergic; Thioinosine | 1990 |
Phosphorylation of stathmin and other proteins related to nerve growth factor-induced regulation of PC12 cells.
Topics: Adenosine; Adrenal Gland Neoplasms; Animals; Cell Line; Colforsin; Electrophoresis, Gel, Two-Dimensional; Microtubule Proteins; Neoplasm Proteins; Nerve Growth Factors; Pheochromocytoma; Phosphoproteins; Phosphorylation; Rats; Stathmin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Effects of adenosine and analogs on adenylate cyclase activity in cultured bovine aortic endothelial cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Cattle; Cell Membrane; Cells, Cultured; Colforsin; Isoproterenol; Muscle, Smooth, Vascular; Vasodilator Agents | 1990 |
Characterization of the adenosine receptor in porcine coronary arteries.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Colforsin; Coronary Vessels; Dinoprost; In Vitro Techniques; Kinetics; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Receptors, Purinergic; Swine | 1990 |
Cyclic AMP stimulates serotonin N-acetyltransferase activity in Xenopus retina in vitro.
Topics: 1-Methyl-3-isobutylxanthine; Acetyltransferases; Adenosine; Animals; Arylamine N-Acetyltransferase; Bucladesine; Calcium; Circadian Rhythm; Colforsin; Cyclic AMP; Darkness; Fishes; Guinea Pigs; In Vitro Techniques; Light; Melatonin; Retina; Tyrosine 3-Monooxygenase; Xenopus laevis | 1986 |
Cyclic adenosine monophosphate, calcium, acetylcholine and the current induced by adenosine in the Xenopus oocyte.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Adenosine; Animals; Calcimycin; Calcium; Colforsin; Cyclic AMP; Egtazic Acid; Electrophysiology; Female; Isoproterenol; Oocytes; Potassium; Progesterone; Xenopus laevis | 1986 |
Paradoxical stimulation of human sperm motility by 2-deoxyadenosine.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Caffeine; Calcimycin; Colforsin; Cyclic AMP; Deoxyadenosines; Freezing; Humans; Male; Sperm Motility; Spermatozoa; Stimulation, Chemical | 1986 |
Calcium dependence of vasoactive intestinal peptide-stimulated cyclic AMP accumulation in rat hippocampal slices.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Calcium; Calmodulin; Colforsin; Cyclic AMP; Female; Hippocampus; Magnesium; Norepinephrine; Phosphoric Diester Hydrolases; Rats; Rats, Inbred Strains; Vasoactive Intestinal Peptide | 1987 |
Inducers of adenylate cyclase reverse the effect of leukotriene D4 in isolated working guinea pig heart.
Topics: Adenosine; Adenylyl Cyclases; Animals; Colforsin; Enzyme Induction; Epoprostenol; Fluorometry; Guinea Pigs; Heart; Iloprost; Ischemia; Male; Myocardium; NAD; Oxygen Consumption; SRS-A; Vasoconstriction | 1987 |
Nerve growth factor treatment or cAMP elevation reduces Ca2+/calmodulin-dependent protein kinase III activity in PC12 cells.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adrenal Gland Neoplasms; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Colforsin; Cyclic AMP; Cytosol; Elongation Factor 2 Kinase; Epidermal Growth Factor; Kinetics; Nerve Growth Factors; Pheochromocytoma; Phosphorylation; Protein Kinases | 1987 |
Neuromodulator-mediated phosphorylation of specific proteins in a neurotumor hybrid cell line (NCB-20).
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Alprostadil; Animals; Brain; Calcimycin; Colforsin; Cricetinae; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Embryo, Mammalian; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Hybrid Cells; Immunoassay; Mice; Nerve Tissue Proteins; Neuroblastoma; Neurotransmitter Agents; Phosphoproteins; Phosphorylation; Protein Kinases; Serotonin; Tumor Cells, Cultured; Tyrosine 3-Monooxygenase | 1988 |
Modulation of adenylate cyclase activity in cultured bovine pulmonary arterial endothelial cells. Effects of adenosine and derivatives.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenylyl Cyclases; Animals; Cattle; Cells, Cultured; Colforsin; Endothelium, Vascular; Guanylyl Imidodiphosphate; Pulmonary Artery; Receptors, Adrenergic, beta; Receptors, Purinergic; Structure-Activity Relationship | 1989 |
Comparison of the inhibition of insulin release by activation of adenosine and alpha 2-adrenergic receptors in rat beta-cells.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Animals; Bucladesine; Colforsin; Dose-Response Relationship, Drug; Epinephrine; Insulin; Ion Channels; Islets of Langerhans; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tetradecanoylphorbol Acetate | 1989 |
Adenosine has divergent effects on deoxyribonucleic acid synthesis in FRTL5 cells: inhibition of thyrotropin-stimulated and potentiation of insulin-like growth factor-I-stimulated thymidine incorporation.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Deaminase; Animals; Bucladesine; Cell Line; Cholera Toxin; Colforsin; DNA; DNA Replication; Drug Synergism; Insulin-Like Growth Factor I; Kinetics; Somatomedins; Thymidine; Thyroid Gland; Thyrotropin | 1989 |
Cation and structural requirements for P site-mediated inhibition of adenylate cyclase.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Brain; Colforsin; Deoxyadenine Nucleotides; Dideoxyadenosine; Dideoxynucleosides; Egtazic Acid; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Magnesium; Manganese; Receptors, Purinergic; Structure-Activity Relationship; Thionucleotides | 1989 |
Protective effect of cyclohexyladenosine on adenosine A1-receptors, guanine nucleotide and forskolin binding sites following transient brain ischemia: a quantitative autoradiographic study.
Topics: Adenosine; Adenylyl Cyclases; Animals; Colforsin; Gerbillinae; GTP-Binding Proteins; Hippocampus; In Vitro Techniques; Ischemic Attack, Transient; Male; Receptors, Purinergic | 1989 |
Inhibition of adenylate cyclase in rat brain synaptosomal membranes by GTP and phenylisopropyladenosine is enhanced in hypothyroidism.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Animals; Brain; Colforsin; Enzyme Activation; GTP-Binding Proteins; Guanosine Triphosphate; Hypothyroidism; Phenylisopropyladenosine; Rats; Receptors, Purinergic; Sodium; Synaptosomes; Xanthines | 1989 |
Adenosine receptor-mediated relaxation in coronary artery: evidence for a guanyl nucleotide-binding regulatory protein involvement.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cattle; Cholera Toxin; Colforsin; Coronary Vessels; Ethylmaleimide; GTP-Binding Proteins; In Vitro Techniques; Receptors, Purinergic; Theophylline; Vasodilation | 1989 |
Characteristics of glucose transport in neuronal cells and astrocytes from rat brain in primary culture.
Topics: Adenosine; Animals; Astrocytes; Binding, Competitive; Biological Transport; Brain; Cells, Cultured; Colforsin; Cyclic AMP; Cytochalasin B; Deoxy Sugars; Deoxyglucose; Electrophoresis, Polyacrylamide Gel; Embryo, Mammalian; Mercuric Chloride; Molecular Weight; Monosaccharide Transport Proteins; Neurons; Nucleosides; Phloretin; Phlorhizin; Rats; Rats, Inbred Strains | 1989 |
Glucocorticoid administration increases receptor-mediated and forskolin-stimulated cyclic AMP accumulation in rat brain cerebral cortical slices.
Topics: 2-Chloroadenosine; Adenosine; Adrenocorticotropic Hormone; Animals; Cerebral Cortex; Colforsin; Cyclic AMP; Dexamethasone; In Vitro Techniques; Isoproterenol; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Reference Values; Sodium Fluoride; Vasoactive Intestinal Peptide | 1989 |
Dual effects of protein kinase-C on receptor-stimulated cAMP accumulation in a human T-cell leukemia line.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Blotting, Western; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Humans; Leukemia, T-Cell; Phorbol Esters; Phosphorylation; Protein Kinase C; Receptors, Prostaglandin; Receptors, Purinergic | 1989 |
Aluminum increases agonist-stimulated cyclic AMP production in rat cerebral cortical slices.
Topics: 2-Chloroadenosine; Adenosine; Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Cerebral Cortex; Chlorides; Colforsin; Cyclic AMP; Isoproterenol; Male; Osmolar Concentration; Rats; Solutions; Stimulation, Chemical; Time Factors | 1989 |
Adenosine regulates the release of adrenocorticotropic hormone (ACTH) from cultured anterior pituitary cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Adrenocorticotropic Hormone; Animals; Cells, Cultured; Colforsin; Corticotropin-Releasing Hormone; Female; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Vasoactive Intestinal Peptide; Xanthines | 1989 |
Effects of adenosine analogues on basal, prostaglandin E1- and forskolin-stimulated cyclic AMP formation in intact neuroblastoma cells.
Topics: Adenosine; Adenosine Deaminase; Alprostadil; Animals; Colforsin; Cyclic AMP; Mice; Neuroblastoma; Phenylisopropyladenosine; Receptors, Purinergic; Tumor Cells, Cultured | 1989 |
Effects of defolliculation on membrane current responses of Xenopus oocytes.
Topics: Adenosine; Adenosine Triphosphate; Animals; Cell Separation; Colforsin; Cyclic AMP; Cyclic GMP; Dinoprostone; Dopamine; Female; In Vitro Techniques; Membrane Potentials; Microbial Collagenase; Norepinephrine; Oocytes; Ovarian Follicle; Potassium Channels; Vasoactive Intestinal Peptide; Xenopus laevis | 1989 |
Activation of protein kinase C via the T-cell receptor complex potentiates cyclic AMP responses in T-cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Enzyme Activation; Humans; Inositol; Inositol Phosphates; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Receptors, Antigen, T-Cell; T-Lymphocytes | 1989 |
beta-Adrenergic induced K+ current in Xenopus oocytes: role of cAMP, inhibition by muscarinic agents.
Topics: 1-Methyl-3-isobutylxanthine; 4-Aminopyridine; 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Adenosine; Aminobenzoates; Aminopyridines; Animals; Atropine; Calcimycin; Colforsin; Cyclic AMP; Diterpenes; Female; Isoproterenol; Oocytes; Phosphodiesterase Inhibitors; Potassium; Receptors, Adrenergic, beta; Tetraethylammonium Compounds; Xenopus laevis | 1985 |
Regulation of lipid metabolism by dipyridamole and adenosine antagonists in rat adipocytes.
Topics: Adenosine; Adenylyl Cyclases; Adipose Tissue; Animals; Cells, Cultured; Colforsin; Dipyridamole; Enzyme Activation; Female; Isoproterenol; Lipid Metabolism; Lipolysis; Rats; Rats, Inbred Strains; Xanthines | 1989 |
Protective effects of cyclohexyladenosine following cerebral ischemia in the gerbil hippocampus.
Topics: Adenosine; Animals; Brain Ischemia; Colforsin; Gerbillinae; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hippocampus; Random Allocation; Receptors, Purinergic; Time Factors | 1989 |
Membrane and intracellular effects of adenosine in mouse pancreatic beta-cells.
Topics: Adenosine; Animals; Cell Membrane; Colforsin; Female; Glucose; Guanosine; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Membrane Potentials; Mice; Mice, Inbred Strains; Phenylisopropyladenosine; Thionucleosides | 1989 |
Significance of plasma adenosine in the antiplatelet activity of forskolin: potentiation by dipyridamole and dilazep.
Topics: Adenosine; Adenosine Deaminase; Animals; Azepines; Colforsin; Dilazep; Dipyridamole; Drug Synergism; Humans; In Vitro Techniques; Male; Platelet Aggregation Inhibitors; Rats | 1989 |
Forskolin potentiates myocardial reactive hyperaemia in the open chest dog: the contribution of adenylate cyclase.
Topics: Adenosine; Adenylyl Cyclases; Animals; Colforsin; Coronary Circulation; Coronary Disease; Dogs; Hemodynamics; Hyperemia; Myocardium; Theophylline; Time Factors | 1989 |
Similarities and differences in phorbol ester- and luteinizing-hormone-induced desensitization of rat tumour Leydig-cell adenylate cyclase.
Topics: Adenosine; Adenylyl Cyclases; Animals; Cholera Toxin; Colforsin; Cyclic AMP; In Vitro Techniques; Leydig Cell Tumor; Luteinizing Hormone; Rats; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1987 |
Characterization of adenosine receptors in bone. Studies on the effect of adenosine analogues on cyclic AMP formation and bone resorption in cultured mouse calvaria.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Bone and Bones; Bone Resorption; Cells, Cultured; Colforsin; Cyclic AMP; Mice; Phenylisopropyladenosine; Pyrrolidinones; Receptors, Cyclic AMP; Rolipram; Theophylline | 1987 |
Evidence for adenylate cyclase-coupled A1-adenosine receptors on ventricular cardiomyocytes from adult rat and dog heart.
Topics: Adenosine; Adenosine Deaminase; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Dogs; Heart Ventricles; Isoproterenol; Kinetics; Myocardium; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic | 1987 |
Adenosine and neuropeptide Y enhance alpha 1-adrenoceptor-induced accumulation of inositol phosphates and attenuate forskolin-induced accumulation of cyclic AMP in rat vas deferens.
Topics: Adenosine; Animals; Colforsin; Cyclic AMP; Inositol Phosphates; Male; Neuropeptide Y; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Stimulation, Chemical; Sugar Phosphates; Vas Deferens | 1987 |
Effects of purines and forskolin on haemolysis.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Anesthetics, Local; Animals; Bucladesine; Chlorpromazine; Colforsin; Edetic Acid; Hemolysis; In Vitro Techniques; Polyphosphates; Procaine; Purines; Rats; Xanthines | 1987 |
Cyclic AMP concentrations modulate both calcium flux and hydrolysis of phosphatidylinositol phosphates in mouse T lymphocytes.
Topics: 2-Chloroadenosine; Adenosine; Animals; Calcium; Calcium Channel Blockers; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Hydrolysis; Kinetics; Male; Mice; Mice, Inbred Strains; Phosphatidylinositols; Phosphorylation; Prostaglandins E; T-Lymphocytes | 1988 |
Changes in adenosine receptors during differentiation of 3T3-F442A cells to adipocytes.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adipose Tissue; Animals; Cell Differentiation; Cell Line; Colforsin; Cyclic AMP; Imidazoles; Isoproterenol; Mice; Phenylisopropyladenosine; Receptors, Purinergic; Theophylline | 1988 |
Selective amplification of luteinizing hormone by adenosine in rat luteal cells.
Topics: Adenosine; Adenosine Triphosphate; Animals; Cholera Toxin; Colforsin; Corpus Luteum; Cyclic AMP; Drug Interactions; Ethers; Female; Ionomycin; Isoproterenol; Kinetics; Luteal Cells; Luteinizing Hormone; Rats | 1988 |
Impaired mobility of human T lymphocyte surface molecules during inactive systemic lupus erythematosus. Relationship to a defective cAMP pathway.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adult; Antigens, Surface; Azides; Colforsin; Cyclic AMP; Female; Humans; Immunologic Capping; Lupus Erythematosus, Systemic; Male; Receptors, Cyclic AMP; T-Lymphocytes | 1988 |
[Functional changes induced by adrenergic purinergic receptors and adenyl cyclase activators in the isolated heart].
Topics: Adenosine; Amrinone; Animals; Colforsin; Coronary Circulation; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Perfusion; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, Purinergic | 1987 |
Is a decrease in cyclic AMP a necessary and sufficient signal for maturation of amphibian oocytes?
Topics: Acetylcholine; Adenosine; Animals; Calcium; Calcium Radioisotopes; Colforsin; Cyclic AMP; Egtazic Acid; Female; Kinetics; Oocytes; Progesterone; Xenopus laevis | 1988 |
Adenosine receptors activate adenylate cyclase and enhance secretion from bovine adrenal chromaffin cells in the presence of forskolin.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Adrenal Gland Neoplasms; Adrenal Glands; Animals; Cattle; Chromaffin System; Colforsin; Cyclic AMP; Drug Synergism; Enzyme Activation; Kinetics; Phosphorylation; Receptors, Purinergic; Tumor Cells, Cultured | 1988 |
Evidence for adenosine A1 receptor action in rat jejunal mucosa.
Topics: Adenosine; Adenosine Deaminase; Adenosine-5'-(N-ethylcarboxamide); Animals; Colforsin; Cyclic AMP; In Vitro Techniques; Intestinal Mucosa; Jejunum; Male; Papaverine; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline; Vasodilator Agents | 1988 |
Investigation of dopamine content, synthesis, and release in the rabbit retina in vitro: II. Effects of high potassium, adenylate cyclase activators, and N-n-propyl-3-(3-hydroxyphenyl) piperidine.
Topics: 2-Chloroadenosine; Adenosine; Adenylyl Cyclases; Animals; Calcium; Colforsin; Dopamine; Enzyme Activation; Female; Male; Piperidines; Potassium; Rabbits; Retina; Tyrosine 3-Monooxygenase; Vasoactive Intestinal Peptide | 1986 |
Phorbol esters enhance neurotransmitter-stimulated cyclic AMP production in rat brain slices.
Topics: 2-Chloroadenosine; Adenosine; Animals; Brain; Colforsin; Cyclic AMP; Dinoprostone; Drug Synergism; Isoproterenol; Male; Molecular Weight; Neurotransmitter Agents; Phorbol Esters; Phosphorylation; Prostaglandins E; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Tissue Distribution; Vasoactive Intestinal Peptide | 1986 |
A subtype of adenosine receptors mediating pigment dispersion in leucophores of the medaka: evidence for an A2-receptor.
Topics: Adenosine; Animals; Catecholamines; Chlorides; Chromatophores; Colforsin; Cyprinodontiformes; Dipyridamole; In Vitro Techniques; Kinetics; Lithium; Lithium Chloride; Oryzias; Propranolol; Purines; Receptors, Purinergic; Xanthines | 1987 |
Inhibition by forskolin of excitatory amino acid-induced accumulation of cyclic AMP in guinea pig hippocampal slices.
Topics: Adenosine; Amino Acids; Animals; Aspartic Acid; Chlorides; Colforsin; Cyclic AMP; Cysteine; Drug Interactions; Ethylmaleimide; Glutamates; Glutamic Acid; Guanosine Triphosphate; Guinea Pigs; Hippocampus; Histamine; Male; N-Methylaspartate; Neurotransmitter Agents; Veratridine | 1988 |
Expression of receptors, linked to cyclic AMP formation by cultures of human fetal astrocytes.
Topics: Adenosine; Adrenergic beta-Agonists; Astrocytes; Brain; Cell Line; Colforsin; Cyclic AMP; Fetus; Humans; Practolol; Receptors, Adrenergic, beta | 1988 |
Electroconvulsive shock (ECS) and the adenosine neuromodulatory system: effect of single and repeated ECS on the adenosine A1 and A2 receptors, adenylate cyclase, and the adenosine uptake site.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Brain; Cerebellum; Cerebral Cortex; Colforsin; Corpus Striatum; Electroshock; Hippocampus; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Purinergic; Thioinosine | 1989 |
The rat testicular A1 adenosine receptor-adenylate cyclase system.
Topics: Adenosine; Adenylyl Cyclases; Affinity Labels; Animals; Colforsin; Guanylyl Imidodiphosphate; Iodine Radioisotopes; Isoproterenol; Male; Phenylisopropyladenosine; Photochemistry; Rats; Rats, Inbred Strains; Receptors, Purinergic; Solubility; Testis | 1986 |
Evidence for two different stimulatory adenylate cyclase coupling mechanisms in rat renal papilla.
Topics: Adenosine; Adenosine Diphosphate Ribose; Adenosine-5'-(N-ethylcarboxamide); Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cell Membrane; Cell-Free System; Cholera Toxin; Colforsin; Enzyme Activation; Fluorides; GTP-Binding Proteins; Kidney Medulla; Manganese; Pertussis Toxin; Rats; Receptors, Angiotensin; Receptors, Purinergic; Receptors, Vasopressin; Vasopressins; Virulence Factors, Bordetella | 1986 |
Fat cell adenylate cyclase system. Enhanced inhibition by adenosine and GTP in the hypothyroid rat.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Adipose Tissue; Animals; Cell Membrane; Colforsin; Cyclic AMP; Diterpenes; Female; GTP-Binding Proteins; Guanosine Triphosphate; Hypothyroidism; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic | 1985 |
Adenosine-induced depression of synaptic transmission in the isolated olfactory cortex: receptor identification.
Topics: Adenosine; Animals; Central Nervous System; Colforsin; Cyclic AMP; Diterpenes; Evoked Potentials; Female; Guinea Pigs; Intracellular Membranes; Male; Norepinephrine; Olfactory Pathways; Phosphodiesterase Inhibitors; Receptors, Cell Surface; Receptors, Purinergic; Synapses; Synaptic Transmission; Theophylline | 1985 |
Characterization of pre- and post-junctional adenosine receptors in guinea-pig ileum.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cholinergic Fibers; Colforsin; Cyclic AMP; Diterpenes; Electric Stimulation; Gastrointestinal Motility; Guinea Pigs; Ileum; Male; Muscle Contraction; Muscle, Smooth; Neuromuscular Junction; Phenylisopropyladenosine; Pyrrolidinones; Receptors, Cell Surface; Receptors, Neurotransmitter; Receptors, Purinergic; Rolipram; Synaptic Transmission | 1985 |
Properties required of a functional Ni, the GTP regulatory complex that mediates the inhibitory actions of neurotransmitters on adenylate cyclase.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adipose Tissue; Animals; Cell Membrane; Cerebral Cortex; Colforsin; Diterpenes; Enzyme Activation; Ethylmaleimide; GTP-Binding Proteins; Guanosine Triphosphate; Kinetics; Macromolecular Substances; Magnesium; Receptors, Adrenergic, beta; Receptors, Cell Surface; Receptors, Purinergic | 1985 |
Regulation of adenosine 3':5'-monophosphate-dependent protein kinase in cerebral cortex.
Topics: Adenosine; Animals; Cerebral Cortex; Colforsin; Cyclic AMP; Diterpenes; In Vitro Techniques; Male; Norepinephrine; Protein Kinases; Rats; Rats, Inbred Strains | 1985 |
Adenosine analogues stimulate cyclic AMP formation in rabbit cerebral microvessels via adenosine A2-receptors.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Cats; Cerebral Cortex; Colforsin; Cyclic AMP; Diterpenes; Microcirculation; Phenylisopropyladenosine; Pyrrolidinones; Rabbits; Receptors, Cell Surface; Receptors, Purinergic; Rolipram | 1985 |
Biochemical characterization of a filtered synaptoneurosome preparation from guinea pig cerebral cortex: cyclic adenosine 3':5'-monophosphate-generating systems, receptors, and enzymes.
Topics: 2-Chloroadenosine; 3',5'-Cyclic-AMP Phosphodiesterases; Acetylcholinesterase; Adenosine; Adenylyl Cyclases; Animals; Butyrylcholinesterase; Cerebral Cortex; Colforsin; Cyclic AMP; Diterpenes; Dose-Response Relationship, Drug; Filtration; Guinea Pigs; Histamine; Microscopy, Electron; Norepinephrine; Receptors, Adrenergic, beta; Receptors, Cell Surface; Receptors, Histamine H2; Receptors, Purinergic; Synaptosomes | 1985 |
Adenosine receptor-mediated changes in cyclic AMP production and DNA synthesis in cultured arterial smooth muscle cells.
Topics: Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; DNA Replication; Muscle, Smooth, Vascular; Phenylisopropyladenosine; Platelet-Derived Growth Factor; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic | 1985 |
Adenosine potentiates lutropin-stimulated cyclic AMP production and inhibits lutropin-induced desensitization of adenylate cyclase in rat Leydig tumour cells.
Topics: Adenosine; Adenylyl Cyclases; Animals; Cholera Toxin; Colforsin; Cyclic AMP; Dipyridamole; Leydig Cell Tumor; Luteinizing Hormone; Phosphodiesterase Inhibitors; Rats | 1985 |
Vasopressin inhibition of cyclic AMP accumulation and effects on the learned response in inbred mouse strains.
Topics: 2-Chloroadenosine; Adenosine; Animals; Arginine Vasopressin; Avoidance Learning; Cerebral Cortex; Colforsin; Conditioning, Psychological; Cyclic AMP; Mice; Mice, Inbred Strains; Norepinephrine; Species Specificity | 1985 |
The protein kinase C activator phorbol-12-myristate-13-acetate enhances cyclic AMP accumulation in pheochromocytoma cells.
Topics: 2-Chloroadenosine; Adenosine; Adrenal Gland Neoplasms; Animals; Cell Line; Colforsin; Cyclic AMP; Enzyme Activation; Pheochromocytoma; Phorbols; Phosphatidylinositols; Protein Kinase C; Rats; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1986 |
Purinergic regulation of basal and arginine vasopressin-stimulated hydraulic conductivity in rabbit cortical collecting tubule.
Topics: Adenosine; Adenylyl Cyclases; Animals; Arginine Vasopressin; Body Water; Colforsin; Cyclic AMP; Deoxyadenosines; Dideoxyadenosine; In Vitro Techniques; Kidney Tubules; Kidney Tubules, Collecting; Osmolar Concentration; Rabbits; Receptors, Cell Surface; Receptors, Purinergic; Ribose; Water-Electrolyte Balance | 1985 |
Effect of adenosine receptor agonists and other compounds on cyclic AMP accumulation in forskolin-treated hippocampal slices.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Deoxyadenosines; Dideoxyadenosine; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Hippocampus; Histamine; Isoproterenol; Male; Phenylisopropyladenosine; Prostaglandins E; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Theophylline; Xanthines | 1986 |
Possible involvement of the Ni-protein in the prejunctional inhibitory effect of a stable adenosine analogue (R-PIA) on noradrenaline release in the rat hippocampus.
Topics: Adenine; Adenosine; Animals; Colforsin; Cyclic AMP; GTP-Binding Proteins; Hippocampus; Male; Norepinephrine; Phenylisopropyladenosine; Rats; Rats, Inbred Strains | 1986 |
Antagonism of forskolin effects by adenosine in isolated hearts and ventricular myocytes.
Topics: Adenosine; Animals; Cell Separation; Colforsin; Cyclic AMP; Guinea Pigs; Heart; Heart Ventricles; In Vitro Techniques; Myocardium | 1986 |
Atrial natriuretic factor receptors are negatively coupled to adenylate cyclase in cultured atrial and ventricular cardiocytes.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Alprostadil; Animals; Animals, Newborn; Cells, Cultured; Colforsin; Dopamine; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Heart Atria; Heart Ventricles; Isoproterenol; Myocardium; Rats; Receptors, Atrial Natriuretic Factor; Receptors, Cell Surface; Thionucleotides | 1986 |
Role of adenylate cyclase in human T-lymphocyte surface antigen capping.
Topics: Adenosine; Adenylyl Cyclases; Adult; Antigens, Surface; Cell Membrane; Cholera Toxin; Colforsin; Enzyme Activation; Female; GTP-Binding Proteins; Humans; Immunologic Capping; Male; Receptors, Cell Surface; Receptors, Cyclic AMP; Receptors, Purinergic; T-Lymphocytes | 1986 |
Pharmacological profile of adenosine A2 receptor in PC12 cells.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenal Gland Neoplasms; Animals; Cell Line; Cell Membrane; Colforsin; Membrane Proteins; Neoplasm Proteins; Pheochromocytoma; Rats; Receptors, Cell Surface; Receptors, Purinergic; Stimulation, Chemical | 1986 |
Adenosine receptors on human lymphocytes.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Alprostadil; Binding Sites; Colforsin; Cyclic AMP; Deoxyadenosines; Dideoxyadenosine; Histamine; Humans; In Vitro Techniques; Isoproterenol; Lymphocytes; Manganese; Neutrophils; Receptors, Purinergic; Theophylline; Vidarabine | 1986 |
A procedure for measuring alpha 2-adrenergic receptor-mediated inhibition of cyclic AMP accumulation in rat brain slices.
Topics: 2-Chloroadenosine; Adenosine; Animals; Brain; Brimonidine Tartrate; Colforsin; Cyclic AMP; In Vitro Techniques; Isoproterenol; Male; Mianserin; Norepinephrine; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vasoactive Intestinal Peptide | 1986 |
Adenosine and oxytocin reverse antagonism of cyclic AMP elevating agents to insulin activation of adipocyte pyruvate dehydrogenase.
Topics: Adenosine; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Bucladesine; Colforsin; Cyclic AMP; Drug Interactions; Enzyme Activation; Insulin; Insulin Antagonists; Isoproterenol; Male; Oxytocin; Phenylisopropyladenosine; Pyruvate Dehydrogenase Complex; Rats; Rats, Inbred Strains | 1987 |
Phorbol-12,13-dibutyrate enhances the cyclic AMP accumulation in rat hippocampal slices induced by adenosine analogues.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Diphosphate Ribose; Adenosine-5'-(N-ethylcarboxamide); Adenylate Cyclase Toxin; Animals; Colforsin; Cyclic AMP; Hippocampus; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxants, Central; Phorbol 12,13-Dibutyrate; Phorbol Esters; Rats; Rats, Inbred Strains; Vasodilator Agents; Virulence Factors, Bordetella | 1987 |
Inhibition of pituitary adenylate cyclase by atrial natriuretic factor.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Animals; Atrial Natriuretic Factor; Colforsin; Corticotropin-Releasing Hormone; Diterpenes; Female; In Vitro Techniques; Muscle Proteins; Pituitary Gland, Anterior; Pituitary Gland, Posterior; Rats; Rats, Inbred Strains; Sodium Fluoride; Vasoactive Intestinal Peptide | 1985 |
Adenosine and ATP: presynaptic effects at the cholinergic nerve terminal.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Colforsin; Corpus Striatum; Receptors, Purinergic; Synaptosomes | 1988 |
Adenosine potentiates forskolin-induced delay of meiotic resumption by mouse denuded oocytes: evidence for an oocyte surface site of adenosine action.
Topics: Adenosine; Adenosine Triphosphate; Animals; Cell Membrane; Colforsin; Drug Synergism; Meiosis; Mice; Oocytes | 1988 |
Melatonin production in organ cultured chicken pineal: modulation by adenosine and its analogs.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Animals; Chickens; Colforsin; Deoxyadenosines; Dipyridamole; Melatonin; Organ Culture Techniques; Phenylisopropyladenosine; Pineal Gland; Thioinosine | 1988 |
Altered responsiveness of adenylate cyclase to adenosine and other agents in the myocardial sarcolemma and aorta of spontaneously-hypertensive rats.
Topics: Adenosine; Adenylyl Cyclases; Animals; Aorta; Colforsin; Epinephrine; Female; Glucagon; Hypertension; In Vitro Techniques; Myocardium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sarcolemma | 1988 |
Interactions of insulin, catecholamines and adenosine in the regulation of glucose transport in isolated rat cardiac myocytes.
Topics: 3-O-Methylglucose; Adenosine; Adenosine Deaminase; Animals; Biological Transport, Active; Catecholamines; Colforsin; Female; Glucose; Heart; In Vitro Techniques; Insulin; Isoproterenol; Kinetics; Methylglucosides; Methylglycosides; Myocardium; Phenylisopropyladenosine; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1986 |
Kinetic analysis of 'rapid onset' neurite formation in NG108-15 cells reveals a dual role for substratum-bound laminin.
Topics: Adenosine; Cell Differentiation; Cell Line; Colforsin; Cycloheximide; Deoxyadenosines; Laminin; Neurons; Tetradecanoylphorbol Acetate; Thionucleosides | 1987 |
Purinergic inhibition in the small intestinal myenteric plexus of the guinea-pig.
Topics: Action Potentials; Adenosine; Animals; Colforsin; Depression, Chemical; Guinea Pigs; In Vitro Techniques; Magnesium; Myenteric Plexus; Neurons; Nucleotides, Cyclic; Time Factors | 1987 |
Heterologous desensitization of the inhibitory A1 adenosine receptor-adenylate cyclase system in rat adipocytes. Regulation of both Ns and Ni.
Topics: Adenosine; Adenylyl Cyclases; Adipose Tissue; Animals; Cell Membrane; Colforsin; Isoproterenol; Kinetics; Male; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Sodium Fluoride | 1987 |
An in vitro analysis of purine-mediated renal vasoconstriction in rat isolated kidney.
Topics: 2-Chloroadenosine; Adenosine; Animals; Colforsin; Male; Methoxamine; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Renal Circulation; Theophylline; Vasoconstriction; Xanthines | 1987 |
Involvement of both inhibitory and stimulatory guanine nucleotide binding proteins in the expression of chronic opiate regulation of adenylate cyclase activity in NG108-15 cells.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alprostadil; Animals; Cell Line; Colforsin; Etorphine; Glioma; GTP-Binding Proteins; Hybrid Cells; Kinetics; Mice; Morphinans; Neuroblastoma; Rats; Sodium Fluoride | 1985 |
Adenosine inhibits forskolin-induced excitation in myenteric neurons.
Topics: Adenosine; Adenylyl Cyclases; Animals; Colforsin; Guinea Pigs; In Vitro Techniques; Myenteric Plexus | 1985 |
Forskolin potentiates the coronary vasoactivity of adenosine in the open-chest dog.
Topics: Adenosine; Adenylyl Cyclases; Animals; Cardiotonic Agents; Colforsin; Coronary Circulation; Coronary Vessels; Diterpenes; Dogs; Drug Synergism; Enzyme Activation; Receptors, Cell Surface | 1984 |
Mutants of PC12 cells with altered cyclic AMP responses.
Topics: 2-Chloroadenosine; 3',5'-Cyclic-AMP Phosphodiesterases; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenylyl Cyclases; Adrenal Gland Neoplasms; Animals; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Diterpenes; Mutation; Phenotype; Pheochromocytoma; Rats | 1984 |
Regulation of adenylate cyclase in cultured cardiocytes from neonatal rats by adenosine and other agonists.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenylyl Cyclases; Animals; Animals, Newborn; Catecholamines; Cells, Cultured; Colforsin; Diterpenes; Enzyme Activation; Guanosine Triphosphate; Microscopy, Electron; Myocardium; Rats; Receptors, Cell Surface; Receptors, Purinergic | 1983 |
Inhibitory actions of adenosine on follicle-stimulating hormone-induced differentiation of cultured rat granulosa cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Cell Differentiation; Cells, Cultured; Colforsin; Cyclic AMP; Dipyridamole; Diterpenes; Female; Follicle Stimulating Hormone; Granulosa Cells; Rats; Receptors, Cell Surface; Receptors, LH | 1984 |
Adenosine receptor mediated increases and decreases in cyclic AMP in hippocampal slices treated with forskolin.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Colforsin; Cyclic AMP; Diterpenes; Hippocampus; Male; Phenylisopropyladenosine; Pyrrolidinones; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Rolipram | 1983 |
Effect of forskolin on alterations of vascular permeability induced with bradykinin, prostaglandin E1, adenosine, histamine and carrageenin in rats.
Topics: Adenosine; Alprostadil; Animals; Bradykinin; Bromelains; Capillary Permeability; Carrageenan; Colforsin; Diterpenes; Dose-Response Relationship, Drug; Edema; Foot Diseases; Histamine; Indomethacin; Male; Prostaglandins E; Rats; Rats, Inbred Strains; Skin | 1983 |
Synergistic inhibition of platelet aggregation by forskolin plus PGE1 or 2-fluoroadenosine: effects of 2',5'-dideoxyadenosine and 5'-methylthioadenosine.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Alprostadil; Colforsin; Deoxyadenosines; Dideoxyadenosine; Diterpenes; Drug Synergism; Humans; In Vitro Techniques; Platelet Aggregation; Prostaglandins E; Thionucleosides | 1982 |
Histamine H3-receptor-induced inhibition of duodenal cholinergic transmission is independent of intracellular cyclic AMP and GMP.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Animals; Clonidine; Colforsin; Cyclic AMP; Cyclic GMP; Duodenum; Guinea Pigs; Histamine Agonists; In Vitro Techniques; Male; Methylhistamines; Parasympathetic Nervous System; Receptors, Histamine H3; Signal Transduction; Synaptic Transmission | 1993 |
Regulation of adenosine receptor function by theophylline in rat aorta.
Topics: Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adrenergic beta-Agonists; Animals; Aorta; Colforsin; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Norbornanes; Rats; Receptors, Purinergic P1; Theophylline | 1994 |
Adenosine-induced hyperpolarization of the membrane voltage in rat mesangial cells in primary culture.
Topics: Adenosine; Animals; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Glomerular Mesangium; Ion Channels; Membrane Potentials; Patch-Clamp Techniques; Potassium Channels; Protein Kinase C; Rats; Receptors, Purinergic P1; Signal Transduction | 1994 |
Is cyclic AMP involved in excitatory amino acid-evoked adenosine release from rat cortical slices?
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Calcium; Chromatography, High Pressure Liquid; Colforsin; Cyclic AMP; Excitatory Amino Acids; Male; N-Methylaspartate; Parietal Lobe; Probenecid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1994 |
ATPo but not cAMPi activates a chloride conductance in mouse ventricular myocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Triphosphate; Animals; Cells, Cultured; Chloride Channels; Colforsin; Cyclic AMP; Cystic Fibrosis; Isoproterenol; Membrane Potentials; Mice; Mice, Knockout; Myocardium; Patch-Clamp Techniques; Stimulation, Chemical | 1995 |
Effects of acute and chronic ethanol on cyclic AMP accumulation in NG108-15 cells: differential dependence of changes on extracellular adenosine.
Topics: Adenosine; Adenosine Deaminase; Animals; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Ethanol; Iloprost; Mice; Neuroblastoma; Rats; Tumor Cells, Cultured | 1995 |
Effect of PGE2 and of agents that raise cAMP levels on macrophage activation induced by IFN-gamma and TNF-alpha.
Topics: Adenosine; Amino Acid Oxidoreductases; Animals; Bucladesine; Cell Differentiation; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Gene Expression; Hematopoietic Stem Cells; Humans; Interferon-gamma; Kinetics; Leishmania; Macrophage Activation; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Nitric Oxide Synthase; Recombinant Proteins; RNA, Messenger; Theophylline; Tumor Necrosis Factor-alpha | 1995 |
Biochemical and pharmacological characterization of periodate-oxidized adenosine analogues at adenosine A1 receptors.
Topics: Adenosine; Adipocytes; Animals; Brain; Colforsin; Cyclic AMP; In Vitro Techniques; Male; Oxidation-Reduction; Periodic Acid; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Thermodynamics | 1995 |
Role of cyclic AMP in stimulation-evoked release of 3H-noradrenaline from rabbit isolated ear artery.
Topics: Adenosine; Animals; Arteries; Colforsin; Cyclic AMP; Ear; Electric Stimulation; Female; Male; Naphthyridines; Norepinephrine; Phosphodiesterase Inhibitors; Pyrimidines; Rabbits; Theophylline; Tritium | 1995 |
Analysis of the proenkephalin second messenger-inducible enhancer in rat striatal cultures.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Base Sequence; Cells, Cultured; Colforsin; Corpus Striatum; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Enhancer Elements, Genetic; Enkephalins; Fetus; Genes, fos; Molecular Sequence Data; Phosphorylation; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Second Messenger Systems; Transcription Factor AP-1 | 1995 |
Comparison of the effect of isobutylmethylxanthine and phosphodiesterase-selective inhibitors on cAMP levels in SH-SY5Y neuroblastoma cells.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adenylyl Cyclase Inhibitors; Cell Line; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Neuroblastoma; Phosphodiesterase Inhibitors; Pyrrolidinones; Rolipram; Tumor Cells, Cultured | 1993 |
Bradykinin inhibits cyclic AMP accumulation in D384-human astrocytoma cells via a calcium-dependent inhibition of adenylyl cyclase.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Astrocytoma; Bradykinin; Brain Neoplasms; Calcimycin; Calcium; Calmodulin; Colforsin; Cyclic AMP; Dopamine; Egtazic Acid; Humans; Hydroquinones; Inositol 1,4,5-Trisphosphate; Neoplasm Proteins; Pyrrolidinones; Rolipram; Signal Transduction; Tumor Cells, Cultured | 1993 |
Cross-talk between muscarinic- and adenosine-receptor signalling in the regulation of cytosolic free Ca2+ and insulin secretion.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine; Atropine; Calcium; Calcium Channels; Carbachol; Cells, Cultured; Colforsin; Cytosol; Enzyme Activation; Glyceraldehyde; Insulin; Insulin Secretion; Ion Channel Gating; Muscarinic Antagonists; Receptors, Muscarinic; Receptors, Purinergic; Signal Transduction; Type C Phospholipases | 1993 |
Existence of rolipram-sensitive phosphodiesterase in rat megakaryocyte.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Diphosphate; Adenylyl Cyclases; Animals; Bone Marrow Cells; Calcimycin; Calcium Channels; Colforsin; Cyclic AMP; Electrophysiology; Female; In Vitro Techniques; Inosine Triphosphate; Isoquinolines; Male; Megakaryocytes; Nystatin; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Protein Kinase C; Pyrrolidinones; Rats; Rats, Wistar; Rolipram | 1993 |
Expression of vascular permeability factor/vascular endothelial growth factor in pig cerebral microvascular endothelial cells and its upregulation by adenosine.
Topics: Adenosine; Animals; Blotting, Northern; Blotting, Western; Brain; Cells, Cultured; Colforsin; Endothelial Growth Factors; Endothelium, Vascular; Gene Expression; In Vitro Techniques; Lymphokines; RNA, Messenger; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1995 |
Adenosine analogs inhibit acetylcholine release and cyclic AMP synthesis in the guinea-pig superior cervical ganglion.
Topics: Acetylcholine; Adenosine; Animals; Colforsin; Cyclic AMP; Depression, Chemical; Electric Stimulation; Guinea Pigs; Imidazoles; Phosphodiesterase Inhibitors; Presynaptic Terminals; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Superior Cervical Ganglion; Sympathetic Nervous System; Xanthines | 1995 |
Evidence for regulated coupling of A1 adenosine receptors by phosphorylation in Zucker rats.
Topics: Adenosine; Adenylyl Cyclases; Adipocytes; Animals; Cell Membrane; Colforsin; Cyclic AMP; Guanine Nucleotides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Iodine Radioisotopes; Iodobenzenes; Obesity; Phosphorylation; Proteins; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Rats, Zucker; Receptors, Purinergic P1 | 1995 |
Nerve growth factor amplifies cyclic AMP production in the HT4 neuronal cell line.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cell Line; Colforsin; Cyclic AMP; Diglycerides; Down-Regulation; Enzyme Activation; Hydrolysis; Mice; Nerve Growth Factors; Neurons; Phosphatidylinositols; Phospholipids; Protein Kinase C | 1995 |
Adenosine A1-receptor mechanisms antagonize beta-adrenergic pulmonary vasodilation in hypoxia.
Topics: Adenosine; Animals; Colforsin; Isoproterenol; Oxygen; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Purinergic P1; Vasodilation | 1994 |
Adrenergic regulation of coronary microcirculation after extracorporeal circulation and crystalloid cardioplegia.
Topics: Adenosine; Animals; Cardioplegic Solutions; Cardiopulmonary Bypass; Colforsin; Coronary Circulation; Crystallization; Extracorporeal Circulation; Female; Heart Arrest, Induced; Isoproterenol; Male; Microcirculation; Nitroprusside; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sodium Fluoride; Swine; Vasodilation | 1994 |
G-proteins and adenylyl cyclase in ovarian granulosa cells of amago salmon (Oncorhynchus rhodurus).
Topics: Adenosine; Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Cell Membrane; Cholera Toxin; Colforsin; Cyclic AMP; Female; Gonadotropins; Granulosa Cells; GTP-Binding Proteins; Guanosine Triphosphate; Molecular Weight; Oncorhynchus; Pertussis Toxin; Virulence Factors, Bordetella | 1994 |
Characterization of the adenosine receptor in microvascular coronary endothelial cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Animals; Antihypertensive Agents; Cells, Cultured; Colforsin; Coronary Vessels; Cyclic AMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Guinea Pigs; Isoproterenol; Myocardium; Phenethylamines; Phenylisopropyladenosine; Receptors, Purinergic P1; Thioinosine; Vasodilator Agents | 1994 |
Evidence that the presynaptic A2a-adenosine receptor of the rat motor nerve endings is positively coupled to adenylate cyclase.
Topics: Acetylcholine; Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Colforsin; Dose-Response Relationship, Drug; Electric Stimulation; Female; Imines; In Vitro Techniques; Male; Phenethylamines; Phosphodiesterase Inhibitors; Phrenic Nerve; Purinergic P1 Receptor Agonists; Pyrrolidinones; Rats; Rats, Wistar; Receptors, Purinergic P1; Rolipram | 1994 |
A1 adenosine receptor inhibition of cyclic AMP formation and radioligand binding in the guinea-pig cerebral cortex.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; Cerebral Cortex; Colforsin; Cyclic AMP; Guinea Pigs; Histamine; In Vitro Techniques; Phenylisopropyladenosine; Phosphatidylinositols; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Radioligand Assay; Receptors, Purinergic P1; Sulfonamides; Vasodilator Agents; Xanthines | 1994 |
Functional adenosine A1 receptors in goldfish brain: regional distribution and inhibition of K(+)-evoked glutamate release from cerebellar slices.
Topics: Adenosine; Adenylyl Cyclases; Amino Acids; Animals; Calcium; Cerebellum; Colforsin; Cyclic AMP; Glutamates; Glutamic Acid; Goldfish; In Vitro Techniques; Membranes; Potassium; Receptors, Purinergic P1; Theophylline | 1994 |
Adenylyl cyclase activity in Alzheimer's disease brain: stimulatory and inhibitory signal transduction pathways are differently affected.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Aged; Aged, 80 and over; Alzheimer Disease; Brain; Cerebellum; Colforsin; Enzyme Activation; Female; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hippocampus; Humans; Male; Manganese; Middle Aged; Neurotransmitter Agents; Purinergic P1 Receptor Antagonists; Signal Transduction | 1994 |
Regulation of A2a adenosine receptor mRNA expression by agonists and forskolin in PC12 cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Colforsin; Cyclic AMP; Gene Expression Regulation, Neoplastic; PC12 Cells; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Receptors, Purinergic P1; RNA, Messenger; Second Messenger Systems; Xanthines | 1994 |
ATP sensitive potassium channels are involved in adenosine A2 receptor mediated coronary vasodilatation in the dog.
Topics: Acetylcholine; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Colforsin; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Glyburide; Guanidines; Ion Channel Gating; Pinacidil; Potassium Channels; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P2; Theophylline; Vasodilator Agents; Xanthines | 1994 |
Chloride dependence of pH modulation by beta-adrenergic agonist in rat cardiomyocytes.
Topics: Adenosine; Animals; Antiporters; Bicarbonates; Bucladesine; Chloride-Bicarbonate Antiporters; Chlorides; Colforsin; Cyclic AMP; Heart Ventricles; Hydrogen-Ion Concentration; In Vitro Techniques; Isoproterenol; Male; Rats; Rats, Wistar; Receptors, Adrenergic, beta | 1994 |
Modulation of cyclic AMP formation by putative metabotropic receptor agonists.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Amino Acids, Dicarboxylic; Aminobutyrates; Animals; Cerebral Cortex; Colforsin; Cyclic AMP; Cycloleucine; Guinea Pigs; Hydrolysis; In Vitro Techniques; Phosphatidylinositols; Receptors, Metabotropic Glutamate | 1994 |
Interaction between metabotropic receptors and purinergic transmission in rat hippocampal slices.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Colforsin; Cycloleucine; Cyclopropanes; Glycine; Hippocampus; In Vitro Techniques; Male; Neurotoxins; Purines; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Synaptic Transmission | 1994 |
Effects of naftidrofuryl oxalate, a 5-HT2 antagonist, on neurotransmission and transduction systems in the gerbil hippocampus.
Topics: Adenosine; Adenylyl Cyclases; Animals; Autoradiography; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dizocilpine Maleate; Gerbillinae; Hippocampus; Inositol 1,4,5-Trisphosphate; Isradipine; Male; Muscimol; Nafronyl; Phorbol Esters; Protein Kinase C; Quinuclidinyl Benzilate; Sensory Receptor Cells; Serotonin Antagonists; Signal Transduction; Synaptic Transmission; Tritium | 1994 |
Effects of PACAP on morphologically identified myenteric neurons in guinea pig small bowel.
Topics: Action Potentials; Adenosine; Animals; Colforsin; Guinea Pigs; Intestine, Small; Male; Myenteric Plexus; Neuroglia; Neurons; Neuropeptides; Neurotransmitter Agents; Pituitary Adenylate Cyclase-Activating Polypeptide; Receptors, Cell Surface; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide; Receptors, Pituitary Hormone | 1993 |
Decreased sensitivity to adenosine in platelets from patients with familial hypercholesterolaemia--a change reversed by cholestyramine treatment.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adult; Cholestyramine Resin; Colforsin; Cyclic AMP; Epoprostenol; Female; Humans; Hyperlipoproteinemia Type II; Male; Platelet Aggregation Inhibitors | 1993 |
The nicardipine-isoprenaline interaction in human and guinea-pig isolated airways.
Topics: Adenosine; Animals; Bronchi; Colforsin; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; Humans; Isoproterenol; Male; Muscle Relaxation; Nicardipine; Nifedipine; Nitroprusside; Theophylline; Trachea | 1994 |
5-Hydroxytryptamine type 2A receptors regulate cyclic AMP accumulation in a neuronal cell line by protein kinase C-dependent and calcium/calmodulin-dependent mechanisms.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Alkaloids; Animals; Calcium; Calmodulin; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Enzyme Activation; Inositol Phosphates; Neurons; Protein Kinase C; Rats; Receptors, Serotonin; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
Platelets from spontaneously hypertensive rats exhibit decreased expression of inhibitory guanine nucleotide regulatory protein. Relation with adenylyl cyclase activity.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Alprostadil; Animals; Blood Platelets; Colforsin; Cyclic AMP; GTP-Binding Proteins; Guanosine Triphosphate; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1993 |
Adenosine A1 receptors and erythropoietin production.
Topics: Adenosine; Carcinoma, Hepatocellular; Colforsin; Cyclic AMP; Erythropoietin; Humans; Liver Neoplasms; Receptors, Purinergic P1; Tumor Cells, Cultured | 1993 |
Multiple mechanisms for desensitization of A2a adenosine receptor-mediated cAMP elevation in rat pheochromocytoma PC12 cells.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adenylyl Cyclases; Animals; Base Sequence; Colforsin; Cyclic AMP; DNA Primers; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Molecular Sequence Data; PC12 Cells; Phenethylamines; Rats; Receptors, Purinergic P1 | 1993 |
Adenosine reduces the potassium conductance of guinea pig submucosal plexus neurons by activating protein kinase A.
Topics: 2-Chloroadenosine; Adenosine; Alkaloids; Animals; Cadmium; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Guinea Pigs; Membrane Potentials; Neurons; Phorbol 12,13-Dibutyrate; Potassium; Staurosporine; Submucous Plexus | 1993 |
Characterisation of the effect of oxygen tension on response of fetal rabbit ductus arteriosus to vasodilators.
Topics: Adenosine; Animals; Atrial Natriuretic Factor; Benzopyrans; Colforsin; Cromakalim; Culture Techniques; Cyclooxygenase Inhibitors; Dinoprostone; Ductus Arteriosus; Epoprostenol; Flurbiprofen; Indomethacin; Nifedipine; Nitroprusside; Norepinephrine; Oxygen; Pyrroles; Rabbits; Vasodilator Agents | 1993 |
Implication of ATP released from atrial, but not papillary, muscle segments of guinea pig by isoproterenol and forskolin.
Topics: Adenosine; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Colforsin; Guinea Pigs; Heart Atria; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Papillary Muscles; Verapamil | 1993 |
Selective A2-adenosine receptor agonists do not alter action potential duration, twitch shortening, or cAMP accumulation in guinea pig, rat, or rabbit isolated ventricular myocytes.
Topics: Action Potentials; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cell Line; Colforsin; Cyclic AMP; Guinea Pigs; Heart; Myocardium; Rabbits; Rats; Receptors, Purinergic | 1993 |
Endogenous adenosine regulates the apparent efficacy of 1-aminocyclopentyl-1S,3R-dicarboxylate inhibition of forskolin-stimulated cyclic AMP accumulation in rat cerebral cortical slices.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cerebral Cortex; Colforsin; Cyclic AMP; Cycloleucine; Female; In Vitro Techniques; Kinetics; Male; Neurotoxins; Rats; Rats, Inbred Strains; Xanthines | 1993 |
Role of extracellular adenosine in ethanol-induced desensitization of cyclic AMP production.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Colforsin; Cyclic AMP; Ethanol; Extracellular Space; PC12 Cells | 1993 |
Regulation of adenosine receptor system in coronary artery: functional studies and cAMP.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Arteries; Colforsin; Coronary Vessels; Cyclic AMP; Female; In Vitro Techniques; Male; Rabbits; Receptors, Purinergic; Sodium Fluoride; Swine; Vasodilation | 1993 |
Pharmacological analysis of vasodilation induced by extracellular adenosine 3',5'-cyclic monophosphate in the isolated and perfused canine coronary artery.
Topics: Adenosine; Adenosine Deaminase; Animals; Colforsin; Coronary Vessels; Cyclic AMP; Dogs; Endothelium, Vascular; Female; In Vitro Techniques; Isoproterenol; Male; Perfusion; Vasodilation | 1993 |
Enhancement of endothelial cAMP accumulation by adenine nucleotides: role of methylxanthine-sensitive sites.
Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Animals; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Endothelium, Vascular; Osmolar Concentration; Prostaglandins; Protein Kinase C; Time Factors; Xanthines | 1993 |
Subtypes of metabotropic excitatory amino acid receptor distinguished by stereoisomers of the rigid glutamate analogue, 1-aminocyclopentane-1,3-dicarboxylate.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cerebral Cortex; Colforsin; Cyclic AMP; Cycloleucine; Glutamates; Guinea Pigs; In Vitro Techniques; Phosphatidylinositols; Receptors, Amino Acid; Receptors, Purinergic; Stereoisomerism | 1993 |
Adenosine inhibits alpha-melanocyte-stimulating hormone release from frog pituitary melanotrophs via an A1 receptor subtype negatively coupled to adenylate cyclase.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; alpha-MSH; Animals; Colforsin; Cyclic AMP; In Vitro Techniques; Phenylisopropyladenosine; Pituitary Gland; Rana ridibunda; Receptors, Purinergic | 1993 |
Comparison of adenosine and muscarinic receptor-mediated effects on protein phosphatase inhibitor-1 activity in the heart.
Topics: Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Carrier Proteins; Colforsin; Depression, Chemical; Enzyme Activation; Enzyme Inhibitors; Female; Guinea Pigs; Heart; Heart Ventricles; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Isoproterenol; Male; Myocardial Contraction; Myocardium; Phenylisopropyladenosine; Phosphoprotein Phosphatases; Protein Kinases; Proteins; Receptors, Muscarinic; Receptors, Purinergic; Stimulation, Chemical; Ventricular Function; Xanthines | 1993 |
Coupling of adenosine receptors to adenylate cyclase in postischemic rat brain.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Binding, Competitive; Brain Ischemia; Calcium; Colforsin; Cyclic AMP; Down-Regulation; Edetic Acid; Egtazic Acid; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Heart Arrest; Male; Models, Biological; Rats; Rats, Wistar; Receptors, Purinergic; Signal Transduction | 1993 |
Epidermal growth factor modulates the lipolytic action of catecholamines in rat adipocytes. Involvement of a Gi protein.
Topics: Adenosine; Adenosine Deaminase; Adipose Tissue; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Epidermal Growth Factor; Glucagon; GTP-Binding Proteins; Isoproterenol; Lipolysis; Male; Rats; Rats, Wistar; Signal Transduction | 1993 |
Retinoid-induced beta-adrenergic inhibitory effect associated with increased thymidine incorporation of fetal rat keratinizing epidermal cells (FRSK cells).
Topics: Acitretin; Adenosine; Adenylyl Cyclases; Animals; Blotting, Northern; Cell Line; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Epidermal Cells; Epidermis; Fetus; Glucocorticoids; Rats; Receptors, Adrenergic, beta; Retinoids; RNA, Messenger; Thymidine; Time Factors; Tritium | 1993 |
Facilitation of [3H]-ACh release by forskolin depends on A2-adenosine receptor activation.
Topics: Acetylcholine; Adenosine; Adenosine Deaminase; Adenylyl Cyclases; Animals; Colforsin; Diaphragm; Female; In Vitro Techniques; Male; Nerve Endings; Phenethylamines; Phenylisopropyladenosine; Phrenic Nerve; Purinergic Antagonists; Purines; Rats; Rats, Wistar; Receptors, Purinergic; Sulfonamides; Xanthines | 1993 |
Altered cellular signalling and decreased platelet sensitivity to adenosine in insulin-dependent diabetic patients with proliferative retinopathy.
Topics: Adenosine; Adenosine Diphosphate; Adenosine-5'-(N-ethylcarboxamide); Binding Sites; Blood Platelets; Cell Membrane; Colforsin; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Epoprostenol; Female; GTP-Binding Proteins; Humans; Middle Aged; Platelet Aggregation; Receptors, Purinergic; Signal Transduction | 1993 |
Activators of protein kinase C but not of phospholipase C modulate adenylate cyclase-responses of normal pig epidermis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Adenylyl Cyclases; Animals; Bradykinin; Cell Division; Cholera Toxin; Colforsin; Cyclic AMP; Diglycerides; Dinoprostone; Enzyme Activation; Enzyme Inhibitors; Epidermal Cells; Epidermal Growth Factor; Epidermis; Epinephrine; Histamine; Isoquinolines; Keratinocytes; Piperazines; Protein Kinase C; Swine; Tetradecanoylphorbol Acetate; Thrombin; Type C Phospholipases | 1995 |
Effects of pH on responses to adenosine, CGS 21680, carbachol and nitroprusside in the isolated perfused superior mesenteric arterial bed of the rat.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antihypertensive Agents; Carbachol; Colforsin; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Mesenteric Arteries; Methoxamine; Nitroprusside; Perfusion; Phenethylamines; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents; Xanthines | 1995 |
Adenosine A2 receptor-mediated stimulation of cyclic AMP in cultured chicken pineal cells.
Topics: 2-Chloroadenosine; Adenosine; Animals; Cells, Cultured; Chickens; Colforsin; Cyclic AMP; Kinetics; Pineal Gland; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline | 1995 |
Functional coupling of adenosine A2a receptor to inhibition of the mitogen-activated protein kinase cascade in Chinese hamster ovary cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Androstadienes; Animals; Arachidonic Acid; Base Sequence; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Membrane; CHO Cells; Cloning, Molecular; Colforsin; Cricetinae; Cyclic AMP; DNA Primers; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Guinea Pigs; Kinetics; Leukocytes; Molecular Sequence Data; Polymerase Chain Reaction; Purinergic P1 Receptor Agonists; Receptors, Purinergic P1; Recombinant Proteins; Signal Transduction; Thrombin; Transfection; Wortmannin | 1996 |
Circadian rhythm in the Ca(2+)-inhibitable adenylyl activity of the rat striatum.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Caffeine; Calcium; Circadian Rhythm; Colforsin; Corpus Striatum; Cyclic AMP; Guanosine Diphosphate; Isoenzymes; Male; Motor Activity; Phenethylamines; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley | 1996 |
Molecular basis for subtype-specific desensitization of inhibitory adenosine receptors. Analysis of a chimeric A1-A3 adenosine receptor.
Topics: Adenosine; Adenosine Triphosphate; Amino Acid Sequence; Animals; Cell Membrane; CHO Cells; Colforsin; Cricetinae; Epitopes; GTP-Binding Proteins; Humans; Kinetics; Molecular Sequence Data; Palmitic Acid; Palmitic Acids; Peptide Fragments; Phosphopeptides; Phosphorylation; Protein Processing, Post-Translational; Purinergic P1 Receptor Agonists; Radioligand Assay; Rats; Receptor Protein-Tyrosine Kinases; Receptors, Purinergic P1; Recombinant Fusion Proteins; Sequence Tagged Sites; Transfection | 1996 |
Differentiation of group 2 and group 3 metabotropic glutamate receptor cAMP responses in the rat hippocampus.
Topics: Adenosine; Adenosine Deaminase; Adenosine-5'-(N-ethylcarboxamide); Amino Acids, Dicarboxylic; Aminobutyrates; Animals; Colforsin; Cyclic AMP; Cycloleucine; Excitatory Amino Acid Agonists; Hippocampus; In Vitro Techniques; Male; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Vasoactive Intestinal Peptide | 1996 |
Dual signalling by the adenosine A2a receptor involves activation of both N- and P-type calcium channels by different G proteins and protein kinases in the same striatal nerve terminals.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Adenosine; Agatoxins; Alkaloids; Animals; Antihypertensive Agents; Benzophenanthridines; Calcium Channel Blockers; Calcium Channels; Cholera Toxin; Cholinergic Fibers; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; GTP-Binding Proteins; Isoquinolines; Neostriatum; Neurons; Phenanthridines; Phenethylamines; Piperazines; Potassium; Presynaptic Terminals; Protein Kinase C; Protein Kinases; Rats; Rats, Wistar; Receptors, Purinergic P1; Signal Transduction; Spider Venoms; Stereoisomerism; Sulfonamides; Tritium; Xanthines | 1996 |
Functional characterization of adenosine A2 receptors in Jurkat cells and PC12 cells using adenosine receptor agonists.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Colforsin; Cyclic AMP; DNA; Humans; Isotope Labeling; Lethal Dose 50; Leukemia, T-Cell; Molecular Sequence Data; PC12 Cells; Phenethylamines; Polymerase Chain Reaction; Purinergic P1 Receptor Agonists; Quinazolines; Rats; Receptors, Purinergic P1; RNA, Messenger; Triazoles; Tumor Cells, Cultured | 1996 |
Adenosine and carbachol are not equivalent in their effects on L-type calcium current in rabbit ventricular cells.
Topics: Adenosine; Aging; Amino Acid Sequence; Animals; Animals, Newborn; Calcium Channels; Carbachol; Colforsin; Cyclic AMP; Heart Ventricles; Isoproterenol; Male; Molecular Sequence Data; Rabbits; Stimulation, Chemical; Therapeutic Equivalency | 1996 |
Modulation of the hyperpolarization-activated current (Ih) by cyclic nucleotides in guinea-pig primary afferent neurons.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Action Potentials; Adenosine; Adenosine Monophosphate; Animals; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Dibutyryl Cyclic GMP; Dinoprostone; Guinea Pigs; In Vitro Techniques; Ion Channels; Neurons, Afferent; Nodose Ganglion; Nucleotides, Cyclic; Patch-Clamp Techniques; Phosphorylation; Second Messenger Systems; Thionucleotides; Trigeminal Ganglion | 1996 |
Forskolin evokes extracellular adenosine accumulation in rat cortical cultures.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adenosine; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Cells, Cultured; Cerebral Cortex; Colforsin; Cyclic AMP; Electrophysiology; Extracellular Space; Neuropeptides; Rats | 1996 |
Defective ATP-dependent mucin secretion by cystic fibrosis pancreatic epithelial cells.
Topics: Adenocarcinoma; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adult; Antigens; Calcium; Carbachol; Cell Line; Colforsin; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelium; Humans; Immunoassay; Mucins; Pancreatic Neoplasms; Receptors, Purinergic P2; Transfection; Tumor Cells, Cultured; Vasoactive Intestinal Peptide | 1996 |
Regulation of tyrosine hydroxylase gene expression by the m1 muscarinic acetylcholine receptor in rat pheochromocytoma cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adrenal Gland Neoplasms; Animals; Atropine; Calcium; Carbachol; Cell Membrane; Chloramphenicol O-Acetyltransferase; Colforsin; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Mice; Mutagenesis, Site-Directed; Pheochromocytoma; Phosphatidylinositols; Quinuclidinyl Benzilate; Rats; Receptor, Muscarinic M1; Receptors, Muscarinic; Recombinant Fusion Proteins; Transcription, Genetic; Tumor Cells, Cultured; Tyrosine 3-Monooxygenase | 1996 |
Adenosine A1 receptors in cultured cerebellar granule cells: role of endogenous adenosine.
Topics: Adenosine; Adenosine Deaminase; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Animals, Newborn; Cell Membrane; Cells, Cultured; Cerebellum; Colforsin; Cyclic AMP; GTP-Binding Proteins; Kinetics; Neurons; Phenylisopropyladenosine; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Time Factors; Xanthines | 1996 |
Phosphorylation of CREB in ovine pars tuberalis is regulated both by cyclic AMP-dependent and cyclic AMP-independent mechanisms.
Topics: Adenosine; Animals; Blood Physiological Phenomena; Blotting, Western; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Dinoprostone; Female; Immunohistochemistry; Male; Melatonin; Phosphorylation; Pituitary Gland, Anterior; Serine; Sheep | 1996 |
Neurite outgrowth of striatal neurons in vitro: involvement of purines in the growth-promoting effect of myenteric plexus explants.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Aminohydrolases; Animals; Cells, Cultured; Colforsin; Drug Interactions; Fibroblast Growth Factors; Fibronectins; Gangliosides; Guanosine Triphosphate; Laminin; Myenteric Plexus; Neostriatum; Nerve Growth Factors; Neurites; Neurons; Neuropeptides; Neurotrophin 3; Rats; Rats, Sprague-Dawley; Serotonin; Tetrodotoxin; Theophylline | 1996 |
Adenosine causes cAMP-dependent activation of chick embryo red cell carbonic anhydrase and 2,3-DPG synthesis.
Topics: 2,3-Diphosphoglycerate; Adenosine; Adenosine Deaminase Inhibitors; Adenylyl Cyclases; Animals; Biological Transport; Carbonic Anhydrases; Chick Embryo; Colforsin; Cyclic AMP; Diphosphoglyceric Acids; Enzyme Activation; Enzyme Inhibitors; Erythrocytes; Fetal Blood; Nucleosides; Protein Biosynthesis; Purinergic P1 Receptor Agonists; Theobromine; Tubercidin | 1996 |
Effect of adenosine on phorbol myristate acetate induced-reactive oxygen metabolite production in cultured mesangial cells.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cells, Cultured; Colforsin; Cyclic AMP; Female; Glomerular Mesangium; Luminescent Measurements; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Tetradecanoylphorbol Acetate | 1996 |
KATP channels mediate adenosine-induced hyperemia in retina.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Benzopyrans; Colforsin; Cromakalim; Cyclic AMP; Dose-Response Relationship, Drug; Fluorescein Angiography; Glyburide; Hyperemia; Muscle, Smooth, Vascular; Potassium Channel Blockers; Potassium Channels; Pyrroles; Regional Blood Flow; Retinal Vessels; Second Messenger Systems; Signal Transduction; Swine; Vasodilation; Vasodilator Agents | 1996 |
Neurite outgrowth in PC12 cells is enhanced by guanosine through both cAMP-dependent and -independent mechanisms.
Topics: Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Animals; Antineoplastic Agents; Colforsin; Cyclic AMP; Enzyme Inhibitors; Guanosine; Guanosine Triphosphate; Nerve Growth Factors; Neurites; PC12 Cells; Rats | 1996 |
Role of potassium channels and nitric oxide in the effects of iloprost and prostaglandin E1 on hypoxic vasoconstriction in the isolated perfused lung of the rat.
Topics: Adenosine; Alprostadil; Animals; Colforsin; Enzyme Inhibitors; Hypoxia; Iloprost; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Potassium Channels; Pulmonary Circulation; Rats; Rats, Wistar; Vasoconstriction; Vasodilator Agents | 1997 |
Suppression of cAMP formation by adenosine in myenteric ganglia from guinea-pig small intestine.
Topics: Adenosine; Adenosine Deaminase; Animals; Colforsin; Cyclic AMP; Drug Antagonism; Ganglia; Guinea Pigs; Histamine; Intestine, Small; Male; Myenteric Plexus; Purinergic P1 Receptor Agonists; Serotonin; Signal Transduction; Stimulation, Chemical; Substance P | 1997 |
Adenosine stimulation of DNA synthesis in human endothelial cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Triphosphate; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA; Endothelium, Vascular; Humans; Kinetics; Poly A; Purinergic P1 Receptor Antagonists; Quinazolines; Tetradecanoylphorbol Acetate; Thioinosine; Thionucleotides; Thymidine; Triazoles; Umbilical Veins | 1997 |
Apical adenosine activates an amiloride-sensitive conductance in human intestinal cell line HT29cl.19A.
Topics: Adenosine; Amiloride; Biological Transport; Bumetanide; Cell Polarity; Chlorides; Colforsin; Colon; Diuretics; Electric Conductivity; Humans; Membrane Potentials; Receptors, Purinergic P1; Sodium; Tumor Cells, Cultured | 1997 |
Mouse cerebellar adenosinergic modulation of ethanol-induced motor incoordination: possible involvement of cAMP.
Topics: Adenosine; Adenylate Cyclase Toxin; Analysis of Variance; Animals; Cerebellar Cortex; Colforsin; Cyclic AMP; Ethanol; Infusions, Parenteral; Male; Mice; Miconazole; Motor Activity; Pertussis Toxin; Purinergic P1 Receptor Agonists; Receptors, Purinergic P1; Thionucleotides; Time Factors; Virulence Factors, Bordetella | 1997 |
The effect of age on adenosine A1 receptor function in the rat heart.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenergic beta-Agonists; Age Factors; Animals; Carbachol; Cardiovascular Agents; Cell Membrane; Colforsin; Heart; Isoproterenol; Male; Muscarinic Agonists; Myocardium; Purinergic P1 Receptor Agonists; Rats; Rats, Inbred F344; Receptors, Purinergic P1; Sulfonic Acids; Theophylline | 1997 |
Agonist-independent effect of an allosteric enhancer of the A1 adenosine receptor in CHO cells stably expressing the recombinant human A1 receptor.
Topics: Adenosine; Adenosine Deaminase; Allosteric Regulation; Animals; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Recombinant Proteins; Thiophenes; Xanthines | 1997 |
Down-regulation of 5-hydroxytryptamine7 receptors by dexamethasone in rat frontocortical astrocytes.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adrenergic beta-Agonists; Animals; Astrocytes; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Dexamethasone; Down-Regulation; Frontal Lobe; Gene Expression; Glucocorticoids; Isoproterenol; Polymerase Chain Reaction; Rats; Rats, Wistar; Receptors, Serotonin; RNA, Messenger; Serotonin; Vasodilator Agents | 1997 |
Protein kinase C activation by serotonin potentiates agonist-induced stimulation of cAMP production in cultured rat retinal pigment epithelial cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Bradykinin; Cells, Cultured; Colforsin; Cyclic AMP; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Isoproterenol; Naphthalenes; Phorbol 12,13-Dibutyrate; Pigment Epithelium of Eye; Protein Kinase C; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Staurosporine | 1997 |
Role of nitric oxide in vasodilator response induced by salbutamol in rat diaphragmatic microcirculation.
Topics: Adenosine; Adrenergic beta-2 Receptor Agonists; Albuterol; Animals; Arginine; Blood Pressure; Colforsin; Diaphragm; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Heart Rate; Isoproterenol; Male; Microcirculation; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Vasodilation | 1997 |
Desensitization and internalization of adenosine A1 receptors in rat brain by in vivo treatment with R-PIA: involvement of coated vesicles.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Animals; Brain; Coated Vesicles; Colforsin; Enzyme Activation; Guanosine Triphosphate; Immunoblotting; Intracellular Membranes; Male; Microsomes; Purinergic P1 Receptor Agonists; Radioligand Assay; Rats; Rats, Wistar; Receptors, Purinergic P1; Vasodilator Agents; Xanthines | 1996 |
[Early stages in mechanisms of glucocorticoids action on human thrombocytes: effect of hydrocortisone on intracellular cAMP and Ca2+].
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Blood Platelets; Calcium; Colforsin; Collagen; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epinephrine; Glucocorticoids; Humans; Hydrocortisone; Intracellular Fluid; Phosphodiesterase Inhibitors; Radioligand Assay; Thapsigargin | 1997 |
Activation of phosphodiesterase IV during desensitization of the A2A adenosine receptor-mediated cyclic AMP response in rat pheochromocytoma (PC12) cells.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adrenal Gland Neoplasms; Animals; Blotting, Western; Caffeine; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 4; Enzyme Activation; Enzyme Inhibitors; Isoquinolines; Kinetics; PC12 Cells; Phenethylamines; Pheochromocytoma; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Polymerase Chain Reaction; Purinergic P1 Receptor Agonists; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; Recombinant Proteins; Sulfonamides | 1997 |
Nerve growth factor (NGF) expression in rat microglia is induced by adenosine A2a-receptors.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Animals, Newborn; Antihypertensive Agents; Bucladesine; Colforsin; Gene Expression; Microglia; Nerve Growth Factors; Phenethylamines; Polymerase Chain Reaction; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Vasodilator Agents; Xanthines | 1997 |
Posttranscriptional regulation of collagenase-1 gene expression in synoviocytes by adenosine receptor stimulation.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Colforsin; Collagenases; Cyclic AMP Response Element-Binding Protein; Enzyme Activation; Gene Expression Regulation; Half-Life; Humans; Matrix Metalloproteinase 1; Promoter Regions, Genetic; Protein Processing, Post-Translational; Receptors, Purinergic P1; RNA, Messenger; Synovial Membrane; Transcription Factor AP-1 | 1997 |
The role of cyclic AMP as a precursor of extracellular adenosine in the rat hippocampus.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Animals; Colforsin; Cyclic AMP; Diterpenes; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Guanosine Monophosphate; Hippocampus; In Vitro Techniques; Male; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theophylline | 1997 |
KATP channels contribute to beta- and adenosine receptor-mediated pulmonary vasorelaxation.
Topics: Acetylcholine; Adenosine; Adenylyl Cyclases; Animals; ATP-Binding Cassette Transporters; Colforsin; Cromakalim; Cyclic AMP; Cyclic GMP; Glyburide; In Vitro Techniques; Isoproterenol; KATP Channels; Kinetics; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Potassium Channels; Potassium Channels, Inwardly Rectifying; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Purinergic P1; Tolbutamide; Vasodilation | 1997 |
Neuropeptide Y inhibits ion secretion in intestinal epithelium by reducing chloride and potassium conductance.
Topics: Adenosine; Calcium; Carbachol; Cell Line; Chloride Channels; Chlorides; Colforsin; Cyclic AMP; Electric Conductivity; Electric Impedance; Epithelium; Humans; Intestinal Mucosa; Membrane Potentials; Neuropeptide Y; Potassium Channels | 1998 |
Regulation of vascular endothelial growth factor expression by cAMP in rat aortic smooth muscle cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenylyl Cyclases; Animals; Aorta; Cobalt; Colforsin; Cyclic AMP; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Activation; Fibroblasts; Gene Expression Regulation; Iloprost; Isoproterenol; Lymphokines; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Rats; RNA, Messenger; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1998 |
Characterization and regulation of adenosine transport in T84 intestinal epithelial cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Affinity Labels; Biological Transport; Carrier Proteins; Cells, Cultured; Colforsin; Down-Regulation; Humans; Intestinal Mucosa; Kinetics; Membrane Proteins; Nucleoside Transport Proteins; Sodium; Tetradecanoylphorbol Acetate; Thioinosine; Vasodilator Agents | 1998 |
Autocrine regulation of endothelial exocytosis: von Willebrand factor release is induced by prostacyclin in cultured endothelial cells.
Topics: Adenosine; Cells, Cultured; Colforsin; Cyclic AMP; Endothelium, Vascular; Epoprostenol; Exocytosis; Humans; Iloprost; Molsidomine; Nitric Oxide; Nitroprusside; Thrombin; von Willebrand Factor | 1998 |
Adenosine 3':5'-cyclic monophosphate induces regulated secretion of tissue-type plasminogen activator and von Willebrand factor from cultured human endothelial cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Bucladesine; Calcium; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Endothelium, Vascular; Epoprostenol; Humans; Isoproterenol; Second Messenger Systems; Secretory Rate; Thrombin; Tissue Plasminogen Activator; von Willebrand Factor | 1998 |
Rat striatal adenosinergic modulation of ethanol-induced motor impairment: possible role of striatal cyclic AMP.
Topics: Adenosine; Animals; Central Nervous System Depressants; Colforsin; Corpus Striatum; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Ethanol; Male; Motor Neurons; Motor Skills Disorders; Rats; Rats, Sprague-Dawley | 1998 |
P2X receptors in cochlear Deiters' cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cochlea; Colforsin; Dose-Response Relationship, Drug; Enzyme Activation; Guinea Pigs; Patch-Clamp Techniques; Protein Kinases; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Tetradecanoylphorbol Acetate; Thionucleotides; Uridine Triphosphate; Vasodilator Agents; Vestibular Nucleus, Lateral | 1998 |
Does stimulation of NaCl secretion in in vitro perfused rectal gland tubules of Squalus acanthias increase membrane capacitance?
Topics: Adenosine; Animals; Bucladesine; Chlorides; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Electric Capacitance; Membrane Potentials; Patch-Clamp Techniques; Salt Gland; Sodium Chloride; Squalus acanthias | 1998 |
Evidence that adenosine diphosphate can activate adenylate cyclase via conversion to adenosine in platelet-rich plasma containing magnesium.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Cyclases; Colforsin; Cyclic AMP; Enzyme Activation; Humans; Iloprost; Magnesium; Platelet Aggregation Inhibitors; Platelet Count; Quinazolines; Receptors, Purinergic P2; Reference Values | 1998 |
Effects of YT-146 [2-(1-octynyl) adenosine], an adenosine A2A receptor agonist, on cAMP production and noradrenaline release in PC12 cells.
Topics: Adenosine; Adenosine Triphosphate; Alkynes; Animals; Bucladesine; Calcimycin; Calcium; Carbachol; Cholinergic Agonists; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Ionophores; Isoquinolines; Membrane Potentials; Norepinephrine; PC12 Cells; Potassium Chloride; Purinergic P1 Receptor Agonists; Rats; Receptor, Adenosine A2A; Sulfonamides; Thionucleotides; Tritium; Vasodilator Agents | 1998 |
Selective activation of adenosine A3 receptors with N6-(3-chlorobenzyl)-5'-N-methylcarboxamidoadenosine (CB-MECA) provides cardioprotection via KATP channel activation.
Topics: Adenosine; Adenylyl Cyclases; Animals; Anti-Arrhythmia Agents; Binding, Competitive; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Decanoic Acids; Dose-Response Relationship, Drug; Glyburide; Hydroxy Acids; Hypoglycemic Agents; Myocardial Reperfusion Injury; Myocardium; Perfusion; Potassium Channels; Rabbits; Receptor, Adenosine A3; Receptors, Purinergic P1; Xanthines | 1998 |
Regulation of cAMP-dependent chloride channels in DC1 immortalized rabbit distal tubule cells in culture.
Topics: Adenosine; Animals; Cell Line, Transformed; Cell Membrane Permeability; Chloride Channels; Chlorides; Colforsin; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Fluorescent Dyes; Iodides; Kidney Tubules, Distal; Male; Quinolinium Compounds; Rabbits; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic | 1999 |
Involvement of P1 receptors in the effect of forskolin on cyclic AMP accumulation and export in PC12 cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Colforsin; Cyclic AMP; PC12 Cells; Probenecid; Purinergic P1 Receptor Antagonists; Rats; Receptors, Purinergic P1; Theophylline; Time Factors | 1999 |
Signaling via A2A adenosine receptor in four PC12 cell clones.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Blotting, Western; Colforsin; Cyclic AMP; DNA Primers; GTP-Binding Proteins; PC12 Cells; Phenethylamines; Polymerase Chain Reaction; Purinergic P1 Receptor Agonists; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; Signal Transduction; Vasodilator Agents | 1999 |
Effects of vasoactive mediators on the rat lung pericyte: quantitative analysis of contraction on collagen lattice matrices.
Topics: Adenosine; Animals; Bradykinin; Colforsin; Collagen; In Vitro Techniques; Lung; Male; Microcirculation; Pericytes; Rats; Rats, Sprague-Dawley; Serotonin; Silicone Elastomers; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 1999 |
Masking of forskolin-induced long-term potentiation by adenosine accumulation in area CA1 of the rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Hippocampus; Long-Term Potentiation; Male; Nerve Fibers; Neurons; Probenecid; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Synapses; Thionucleotides; Xanthines | 1999 |
Inhibition by adenosine receptor agonists of synaptic transmission in rat periaqueductal grey neurons.
Topics: Action Potentials; Adenosine; Animals; Colforsin; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Membrane Potentials; Neurons; Patch-Clamp Techniques; Periaqueductal Gray; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Synaptic Transmission | 1999 |
Microelectrode measurements of the effects of basolateral adenosine in polarized human intestinal epithelial cells in culture.
Topics: Acetophenones; Adenosine; Bumetanide; Cell Line; Cell Membrane; Chlorides; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Electric Conductivity; Electric Impedance; Enzyme Inhibitors; Epithelial Cells; Humans; Intestines; Membrane Potentials; Microelectrodes; Phospholipases A; Phospholipases A2; Receptors, Purinergic P1; Theophylline | 1999 |
P2 purinoceptors contribute to ATP-induced inhibition of L-type Ca2+ current in rabbit atrial myocytes.
Topics: 1-Methyl-3-isobutylxanthine; 5'-Nucleotidase; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Calcium-Transporting ATPases; Colforsin; Cyclic AMP; Enzyme Inhibitors; Isoproterenol; Myocardium; Patch-Clamp Techniques; Pertussis Toxin; Potassium Channels; Potassium Channels, Voltage-Gated; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rabbits; Receptors, Purinergic P2; Shal Potassium Channels; Suramin; Virulence Factors, Bordetella; Xanthines | 1999 |
Effects of propentofylline on adenosine receptor activity in Chinese hamster ovary cell lines transfected with human A1, A2A, or A2B receptors and a luciferase reporter gene.
Topics: Adenosine; Animals; CHO Cells; Colforsin; Cricetinae; Genes, Reporter; Humans; Luciferases; Neuroprotective Agents; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Transfection; Xanthines | 1998 |
Amplification of the cyclic AMP response to forskolin in pheochromocytoma PC12 cells through adenosine A(2A) purinoceptors.
Topics: Adenosine; Adenosine Deaminase; Adenosine Monophosphate; Animals; Colforsin; Cyclic AMP; Inosine; Kinetics; PC12 Cells; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; Sulfonamides; Theophylline | 1999 |
Differential modulation of nucleoside transport types in neuroblastoma cells by protein kinase activation.
Topics: Adenosine; Animals; Binding Sites; Biological Transport; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Mice; Neuroblastoma; Protein Kinase C; Sodium; Thioinosine; Tritium; Tumor Cells, Cultured | 1999 |
Thermodynamic in vitro studies as a method to investigate the pharmacodynamic behavior of adenosine A1 receptor ligands.
Topics: Adenosine; Adipocytes; Animals; Brain; Colforsin; Cyclic AMP; Kinetics; Ligands; Male; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Temperature; Thermodynamics | 1999 |
Endothelin enhances adenosine and isoprenaline elevated cyclic AMP levels in rat cerebellar slices.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cerebellum; Colforsin; Cyclic AMP; Endothelin Receptor Antagonists; Endothelin-1; In Vitro Techniques; Isoproterenol; Male; Rats; Rats, Wistar; Receptors, Endothelin; Tritium | 1999 |
Development and reversibility of altered skeletal muscle arteriolar structure and reactivity with high salt diet and reduced renal mass hypertension.
Topics: Acetylcholine; Adenosine; Animals; Arterioles; Calcium; Cholera Toxin; Colforsin; Diet, Sodium-Restricted; Iloprost; Male; Microcirculation; Muscle, Skeletal; Nitroprusside; Rats; Rats, Sprague-Dawley; Vasodilation; Venous Pressure | 1999 |
Regulation of cyclic AMP by extracellular ATP in cultured brain capillary endothelial cells.
Topics: Adenosine; Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Animals; Brain; Capillaries; Cells, Cultured; Cerebrovascular Circulation; Colforsin; Cyclic AMP; Cyclooxygenase Inhibitors; Endothelium, Vascular; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y2; Reverse Transcriptase Polymerase Chain Reaction | 1999 |
A role for extracellular adenosine in time-dependent reversal of long-term potentiation by low-frequency stimulation at hippocampal CA1 synapses.
Topics: Adenosine; Animals; Buspirone; Colforsin; Cyclic AMP; Electric Stimulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Least-Squares Analysis; Long-Term Potentiation; Male; Neurons; Piperazines; Purinergic P1 Receptor Antagonists; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Synapses; Synaptic Transmission; Theobromine; Thionucleotides; Time Factors; Xanthines | 1999 |
Adenosine suppresses protein kinase A- and C-induced enhancement of glutamate release in the hippocampus.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenylyl Cyclases; Animals; Animals, Newborn; Carbachol; Carcinogens; Cells, Cultured; Cholinergic Agonists; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dopamine Agonists; Enzyme Activation; Excitatory Postsynaptic Potentials; Exocytosis; Glutamic Acid; Hippocampus; Patch-Clamp Techniques; Protein Kinase C; Rats; Synaptic Transmission; Tetradecanoylphorbol Acetate | 1999 |
Effect of aging on the negative chronotropic and anti-beta-adrenergic actions of adenosine in the rat heart.
Topics: Adenosine; Adrenergic beta-Antagonists; Aging; Animals; Cardiovascular Agents; Colforsin; Electrocardiography; Heart; Heart Rate; In Vitro Techniques; Male; Myocardium; Purinergic P1 Receptor Antagonists; Rats; Rats, Inbred F344; Receptors, Purinergic P1 | 1999 |
Estradiol inhibits smooth muscle cell growth in part by activating the cAMP-adenosine pathway.
Topics: Adenosine; Adenylyl Cyclases; Animals; Antihypertensive Agents; Aorta; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; DDT; Enzyme Inhibitors; Estradiol; Fetal Proteins; Male; Muscle, Smooth, Vascular; Proline; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Thionucleotides; Thymidine; Tritium; Xanthines | 2000 |
Measurement of adenylate cyclase activity in the right ventricular endomyocardial biopsy samples from patients with chronic congestive heart failure.
Topics: Adenosine; Adenylyl Cyclases; Adult; Biopsy; Cell Membrane; Chronic Disease; Colforsin; Female; Heart Failure; Heart Ventricles; Humans; Male; Middle Aged; Myocardium; Norepinephrine; Spectrometry, Fluorescence | 2000 |
Adenosine induces cyclic-AMP formation and inhibits endothelin-1 production/secretion in guinea-pig tracheal epithelial cells through A(2B) adenosine receptors.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cell Line; Cells, Cultured; Colforsin; Cyclic AMP; Endothelin-1; Epithelial Cells; Guinea Pigs; Humans; Lipopolysaccharides; Male; Protein Biosynthesis; Purinergic P1 Receptor Antagonists; Radioimmunoassay; Receptor, Adenosine A2B; Receptors, Purinergic P1; Trachea | 2000 |
Purinergic and calcium-mediated enhancement of NGF-induced neurite expression in PC12 cells.
Topics: Adenosine; Adenylyl Cyclases; Animals; Calcimycin; Calcium; Colforsin; Nerve Growth Factors; Neurites; PC12 Cells; Rats; Receptors, Purinergic | 1999 |
Promotion of forskolin-induced long-term potentiation of synaptic transmission by caffeine in area CA1 of the rat hippocampus.
Topics: Adenosine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Central Nervous System Stimulants; Colforsin; Cyclic AMP; Drug Synergism; Excitatory Postsynaptic Potentials; Hippocampus; Long-Term Potentiation; Male; Quinazolines; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Triazoles; Xanthines | 1999 |
Regulated von Willebrand factor secretion is associated with agonist-specific patterns of cytoskeletal remodeling in cultured endothelial cells.
Topics: Actins; Adenosine; ADP Ribose Transferases; Biological Transport; Botulinum Toxins; Calcimycin; Calcium; Cell Size; Cells, Cultured; Colchicine; Colforsin; Cyclic AMP; Cytochalasin B; Cytochalasin D; Cytoplasmic Granules; Endothelium, Vascular; Epinephrine; GTPase-Activating Proteins; Histamine; Humans; Ionophores; Microtubules; Myosins; Nucleic Acid Synthesis Inhibitors; Sympathomimetics; Thrombin; Umbilical Veins; Vasodilator Agents; von Willebrand Factor | 2000 |
Sequential changes of [H]forskolin, [H]cyclohexyladenosine and [H]PN200-110 binding sites in the brain of 6-hydroxydopamine-lesioned rats.
Topics: Adenosine; Animals; Autoradiography; Binding Sites; Brain Chemistry; Calcium Channel Blockers; Calcium Channels; Colforsin; Corpus Striatum; Isradipine; Male; Medial Forebrain Bundle; Nerve Degeneration; Oxidopamine; Radioligand Assay; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Substantia Nigra; Sympatholytics; Tritium | 2000 |
Adenosine-induced expression of interleukin-6 in astrocytes through protein kinase A and NF-IL-6.
Topics: Adenosine; Animals; Astrocytes; Base Sequence; CCAAT-Enhancer-Binding Proteins; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; Gene Expression; Humans; Interleukin-6; Mice; Nuclear Proteins; Oligonucleotides, Antisense; Promoter Regions, Genetic; Tissue Distribution; Transcription, Genetic; Transcriptional Activation; Transfection | 2000 |
Exercise training restores adenosine-induced relaxation in coronary arteries distal to chronic occlusion.
Topics: Adenosine; Animals; Arteries; Calcium; Chronic Disease; Colforsin; Coronary Disease; Coronary Vessels; Female; In Vitro Techniques; Isoproterenol; Nitroprusside; Osmolar Concentration; Physical Conditioning, Animal; Swine; Swine, Miniature; Vasodilation; Vasodilator Agents | 2000 |
Stimulatory and inhibitory effects of adenosine A(2A) receptors on nerve growth factor-induced phosphorylation of extracellular regulated kinases 1/2 in PC12 cells.
Topics: Adenosine; Animals; Colforsin; Cyclic AMP; Drug Synergism; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nerve Growth Factor; PC12 Cells; Phenethylamines; Phosphorylation; Purinergic P1 Receptor Agonists; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; Signal Transduction | 2000 |
Mechanism of adenosine-induced vasodilation in rat diaphragm microcirculation.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Blood Flow Velocity; Colforsin; Diaphragm; Dose-Response Relationship, Drug; Glyburide; Laser-Doppler Flowmetry; Male; Microcirculation; Potassium Channel Blockers; Potassium Channels; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Vasodilation; Vasodilator Agents | 2000 |
Dominance of G(s) in doubly G(s)/G(i)-coupled chimaeric A(1)/A(2A) adenosine receptors in HEK-293 cells.
Topics: Adenosine; Adenylate Cyclase Toxin; Amino Acid Sequence; Animals; Cell Line; Cell Membrane; Colforsin; Cyclic AMP; DNA, Complementary; Dogs; Dose-Response Relationship, Drug; GTP-Binding Proteins; Humans; Ligands; Models, Biological; Molecular Sequence Data; Mutagenesis, Site-Directed; Pertussis Toxin; Phenethylamines; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Recombinant Proteins; Transfection; Virulence Factors, Bordetella | 2000 |
Activation of A(3) adenosine receptor induces calcium entry and chloride secretion in A(6) cells.
Topics: Adenosine; Animals; Calcium; Calcium Signaling; Cell Line; Chlorides; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dihydropyridines; Electric Conductivity; Epithelial Cells; Kidney; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyridines; Receptor, Adenosine A3; Receptors, Purinergic P1; Rolipram; Signal Transduction | 2000 |
Leptin-induced lipolysis opposes the tonic inhibition of endogenous adenosine in white adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenylate Cyclase Toxin; Adipocytes; Adipose Tissue; Animals; Bucladesine; Cells, Cultured; Colforsin; Kinetics; Leptin; Lipolysis; Male; Obesity; Purinergic P1 Receptor Antagonists; Rats; Rats, Mutant Strains; Rats, Zucker; Recombinant Proteins; Signal Transduction; Virulence Factors, Bordetella | 2001 |
Beta,gamma-methylene ATP-induced cAMP formation in C6Bu-1 cells: involvement of local metabolism and subsequent stimulation of adenosine A2B receptor.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cell Membrane; Colforsin; Cyclic AMP; Enzyme Inhibitors; Extracellular Space; Nucleotidases; Purinergic Antagonists; Purinergic P2 Receptor Agonists; Rats; Receptor, Adenosine A2B; Receptors, Purinergic P1; Tumor Cells, Cultured | 2001 |
Functional and molecular characterization of receptor subtypes mediating coronary microvascular dilation to adenosine.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Animals; Antihypertensive Agents; Blotting, Western; Colforsin; Coronary Vessels; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Female; Glyburide; Heart; Hypoglycemic Agents; In Situ Hybridization; Male; Microcirculation; Myocardium; Peptides; Phenethylamines; Potassium Channel Blockers; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; Stress, Physiological; Swine; Thionucleotides; Tissue Distribution; Triazines; Triazoles | 2001 |
Adenosine signaling in outer medullary descending vasa recta.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenine; Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Angiotensin II; Animals; Calcimycin; Calcium; Colforsin; Cyclic AMP; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Female; Ionophores; Kidney Medulla; Kinetics; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Signal Transduction; Thromboxane A2; Vasodilation | 2001 |
Adenosine enhances neuroexcitability by inhibiting a slow postspike afterhyperpolarization in rabbit vagal afferent neurons.
Topics: Action Potentials; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cadmium; Colforsin; Neurons, Afferent; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rabbits; Receptors, Purinergic P1; Time Factors; Vagus Nerve; Xanthines | 2001 |
Activation of protein kinase A and atypical protein kinase C by A(2A) adenosine receptors antagonizes apoptosis due to serum deprivation in PC12 cells.
Topics: Adenosine; Animals; Apoptosis; Blotting, Western; Cell Membrane; Cell Nucleus; Cell Survival; Chromones; Colforsin; Coloring Agents; Culture Media, Serum-Free; Cyclic AMP-Dependent Protein Kinases; Cytosol; DNA Fragmentation; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Flow Cytometry; Genes, Dominant; MAP Kinase Signaling System; Models, Biological; Morpholines; PC12 Cells; Phenethylamines; Phosphoinositide-3 Kinase Inhibitors; Phosphoprotein Phosphatases; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Transfection | 2001 |
Neutrophil-epithelial crosstalk at the intestinal lumenal surface mediated by reciprocal secretion of adenosine and IL-6.
Topics: Activating Transcription Factors; Adenosine; Animals; Blood Proteins; Cell Line; Chlorocebus aethiops; Colforsin; COS Cells; Cyclic AMP Response Element-Binding Protein; Dose-Response Relationship, Drug; Epithelial Cells; Interleukin-6; Intestinal Mucosa; Neutrophils; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A2B; Receptors, Purinergic P1; Salmonella typhimurium; Signal Transduction; Time Factors; Transcription Factors; Transcription, Genetic; Tumor Necrosis Factor-alpha | 2001 |
Endogenous cyclic AMP-adenosine pathway regulates cardiac fibroblast growth.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Adenylyl Cyclase Inhibitors; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Analysis of Variance; Animals; Cell Division; Colforsin; Cyclic AMP; DNA; Fibroblasts; Isoproterenol; Male; Myocardium; Norepinephrine; Protein Biosynthesis; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley | 2001 |
Adenosine A(1) receptor-mediated inhibition of protein kinase A-induced calcitonin gene-related peptide release from rat trigeminal neurons.
Topics: Adenosine; Analgesics, Opioid; Animals; Calcitonin Gene-Related Peptide; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Drug Interactions; Fentanyl; Male; Neurons; Phenethylamines; Phosphorylation; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Receptors, Purinergic P1; Receptors, Serotonin; Serotonin Receptor Agonists; Sumatriptan; Synaptic Vesicles; Trigeminal Nerve | 2001 |
Regulation of p42/p44 mitogen-activated protein kinase by the human adenosine A3 receptor in transfected CHO cells.
Topics: Adenosine; Androstadienes; Animals; CHO Cells; Chromones; Colforsin; Cricetinae; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Humans; Luciferases; Mitogen-Activated Protein Kinase 1; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Receptor, Adenosine A3; Receptors, Purinergic P1; Recombinant Fusion Proteins; Wortmannin | 2001 |
Pharmacological characterization of adenosine receptors in PGT-beta mouse pineal gland tumour cells.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Calcium; Colforsin; Cyclic AMP; Dihydropyridines; Dose-Response Relationship, Drug; Enzyme Activation; Estrenes; Gene Expression Regulation, Neoplastic; GTP-Binding Proteins; Inositol 1,4,5-Trisphosphate; Isoproterenol; Mice; Mice, Inbred CBA; Pertussis Toxin; Phospholipases; Pinealoma; Pyrrolidinones; Receptor, Adenosine A2B; Receptor, Adenosine A3; Receptors, Purinergic P1; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured; Virulence Factors, Bordetella | 2001 |
Differential regulations between adenosine triphosphate (ATP)- and uridine triphosphate-induced Cl(-) secretion in bovine tracheal epithelium. Direct stimulation of P1-like receptor by ATP.
Topics: Adenosine; Adenosine Triphosphate; Amiloride; Animals; Calcium; Cattle; Cells, Cultured; Chloride Channels; Chlorides; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Diuretics; Electrophysiology; Enzyme Inhibitors; Purinergic Agonists; Purinergic Antagonists; Receptors, Purinergic; Respiratory Mucosa; Signal Transduction; Spectrometry, Fluorescence; Trachea; Uridine Triphosphate | 2001 |
Chondrocytes respond to adenosine via A(2)receptors and activity is potentiated by an adenosine deaminase inhibitor and a phosphodiesterase inhibitor.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Animals; Cartilage, Articular; Cells, Cultured; Chondrocytes; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Horses; Lipopolysaccharides; Nitric Oxide; Phosphodiesterase Inhibitors; Receptors, Cytokine | 2002 |
Differential modulation of nucleus accumbens synapses.
Topics: Adenosine; Animals; Colforsin; Electric Conductivity; Excitatory Postsynaptic Potentials; In Vitro Techniques; Male; Narcotics; Neurons; Nucleus Accumbens; Rats; Rats, Wistar; Synapses | 2002 |
Early activation of the p42/p44MAPK pathway mediates adenosine-induced nitric oxide production in human endothelial cells: a novel calcium-insensitive mechanism.
Topics: Adenosine; Androstadienes; Arginine; Biological Transport; Butadienes; Calcium; Cells, Cultured; Chromones; Colforsin; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Fetus; Flavonoids; Gene Expression; Genistein; Humans; Hydrogen-Ion Concentration; MAP Kinase Signaling System; Membrane Potentials; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitriles; Phenethylamines; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Potassium; Protein Isoforms; Purinergic P1 Receptor Agonists; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Wortmannin | 2002 |
Adenosine A(2a) receptor-mediated inhibition of rod opsin mRNA expression in tiger salamander.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenylyl Cyclases; Ambystoma; Animals; Cells, Cultured; Colforsin; Darkness; Enzyme Inhibitors; Gene Expression Regulation; Purinergic P1 Receptor Agonists; Receptor, Adenosine A2A; Receptors, Purinergic P1; Retina; Retinal Rod Photoreceptor Cells; RNA, Messenger; Rod Opsins | 2002 |
CFTR null mutation altered cAMP-sensitive and swelling-activated Cl- currents in primary cultures of mouse nephron.
Topics: Adenosine; Animals; Calcium; Cell Size; Cells, Cultured; Chloride Channels; Chlorides; Colforsin; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Enzyme Inhibitors; Hypotonic Solutions; Kidney Tubules; Mice; Mice, Inbred C57BL; Mice, Inbred CFTR; Mice, Knockout; Mutation; Nephrons; Patch-Clamp Techniques; Transfection | 2003 |
CFTR-dependent and -independent swelling-activated K+ currents in primary cultures of mouse nephron.
Topics: Adenosine; Animals; Calcium; Cell Size; Cells, Cultured; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Enzyme Inhibitors; Hypotonic Solutions; Mice; Mice, Inbred C57BL; Mice, Inbred CFTR; Nephrons; Patch-Clamp Techniques; Potassium; Potassium Channel Blockers; Potassium Channels | 2003 |
Differential allosteric modulation by amiloride analogues of agonist and antagonist binding at A(1) and A(3) adenosine receptors.
Topics: Adenosine; Allosteric Regulation; Amiloride; Animals; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Diuretics; Dose-Response Relationship, Drug; Drug Interactions; Humans; Imidazoles; Kinetics; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Radioligand Assay; Receptor, Adenosine A2A; Receptor, Adenosine A3; Receptors, Purinergic P1; Transfection; Tritium; Xanthines | 2003 |
The human D2 dopamine receptor synergizes with the A2A adenosine receptor to stimulate adenylyl cyclase in PC12 cells.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenine; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenylyl Cyclases; Animals; Benzamides; Binding, Competitive; Cell Cycle; Cell Membrane; Cofilin 1; Colforsin; Cyclic AMP; Cytoskeletal Proteins; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Enzyme Activation; Gene Expression; Glutamic Acid; Humans; Membrane Potentials; Patch-Clamp Techniques; PC12 Cells; Pertussis Toxin; Phenethylamines; Phosphodiesterase Inhibitors; Phosphoproteins; Propionates; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrrolidines; Quinpirole; Radioligand Assay; Rats; Receptors, Dopamine D2; Receptors, Purinergic P1; Thionucleotides; Transfection; Triazines; Triazoles; Xenopus Proteins | 2003 |
Adenosine inhibits activation-induced T cell expression of CD2 and CD28 co-stimulatory molecules: role of interleukin-2 and cyclic AMP signaling pathways.
Topics: Adenosine; Animals; Antibodies, Monoclonal; Caffeine; CD2 Antigens; CD28 Antigens; CD3 Complex; Cell Cycle; Colforsin; Cyclic AMP; Female; Flavins; Interleukin-2; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Phenethylamines; Receptors, Interleukin-2; Receptors, Purinergic P1; Signal Transduction; T-Lymphocytes; Tyrosine | 2003 |
Modulation of GABA release during morphine withdrawal in midbrain neurons in vitro.
Topics: Action Potentials; Adenosine; Affinity Labels; Animals; Colforsin; Cyclic AMP; Dipyridamole; Dose-Response Relationship, Drug; Drug Interactions; Enkephalins; Enzyme Inhibitors; gamma-Aminobutyric Acid; In Vitro Techniques; Isoquinolines; Male; Mesencephalon; Mice; Mice, Inbred C57BL; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Narcotics; Neural Inhibition; Neurons; Patch-Clamp Techniques; Periaqueductal Gray; Probenecid; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Substance Withdrawal Syndrome; Sulfonamides; Synaptic Transmission; Thioinosine; Time Factors; Uricosuric Agents; Vasodilator Agents; Xanthines | 2003 |
Inhibition of bile salt-induced apoptosis by cyclic AMP involves serine/threonine phosphorylation of CD95.
Topics: Adenosine; Animals; Apoptosis; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; ErbB Receptors; fas Receptor; JNK Mitogen-Activated Protein Kinases; Male; Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Rats, Wistar; Serine; Taurolithocholic Acid; Threonine | 2004 |
Down-regulation of rat brain adenosine A1 receptors at the end of pregnancy.
Topics: Adenosine; Adenylyl Cyclases; Aldehyde-Lyases; Animals; Antihypertensive Agents; Binding Sites; Blotting, Northern; Brain; Cell Membrane; Colforsin; Densitometry; Dose-Response Relationship, Drug; Down-Regulation; Drug Interactions; Female; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Immunoblotting; Phenethylamines; Pregnancy; Rats; Rats, Wistar; Receptor, Adenosine A1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tritium; Xanthines | 2004 |
An adenosine analog (IB-MECA) inhibits anchorage-dependent cell growth of various human breast cancer cell lines.
Topics: Adenosine; Adenosine A3 Receptor Agonists; Adenosine A3 Receptor Antagonists; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Colforsin; Cyclic AMP; Female; Gene Expression Regulation, Neoplastic; Humans; Receptor, Adenosine A3; Signal Transduction | 2004 |
Adenosine inhibits GABAergic and glycinergic transmission in adult rat substantia gelatinosa neurons.
Topics: 4-Aminopyridine; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Animals; Colforsin; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Neurons; Pain; Phorbol 12,13-Dibutyrate; Potassium Channel Blockers; Potassium Channels; Rats; Substantia Gelatinosa; Synaptic Transmission | 2004 |
The activity of constitutive nitric oxide synthase is increased by the pathway cAMP/cAMP-activated protein kinase in human platelets. New insights into the antiaggregating effects of cAMP-elevating agents.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adult; Blood Platelets; Cell Adhesion Molecules; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Humans; Male; Microfilament Proteins; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Up-Regulation | 2004 |
Heterologous desensitization of the sphingosine-1-phosphate receptors by purinoceptor activation in renal mesangial cells.
Topics: Adenosine; Adenosine Triphosphate; Animals; Biotransformation; Blotting, Western; Cells, Cultured; Colforsin; Enzyme Activation; Enzyme Inhibitors; Glomerular Mesangium; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Lysophospholipids; Mitogen-Activated Protein Kinase 1; Protein Kinases; Purinergic Agonists; Purinergic P1 Receptor Agonists; Rats; Receptors, Lysosphingolipid; Sphingosine; Staurosporine | 2004 |
Prostaglandin E2--mediated relaxation of the ductus arteriosus: effects of gestational age on g protein-coupled receptor expression, signaling, and vasomotor control.
Topics: 16,16-Dimethylprostaglandin E2; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenylyl Cyclases; Alprostadil; Animals; Biphenyl Compounds; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Ductus Arteriosus; Enzyme Activation; Female; Gestational Age; Glyburide; Indomethacin; Isometric Contraction; NG-Nitroarginine Methyl Ester; Nitroprusside; Papio; Potassium Channels; Pregnancy; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP3 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Sheep; Signal Transduction; Sodium Fluoride; Thionucleotides; Vasomotor System | 2004 |
Extracellular cyclic AMP and adenosine appearance in adipose tissue of Sus scrofa: effects of exercise.
Topics: 5'-Nucleotidase; Adenosine; Adipocytes; Adipose Tissue; Animals; Cell Membrane; Colforsin; Cyclic AMP; Female; Male; Microdialysis; Phosphoric Diester Hydrolases; Physical Conditioning, Animal; Physical Endurance; Sus scrofa; Xenon Radioisotopes | 2004 |
Autoinhibition of transmitter release from PC12 cells and sympathetic neurons through a P2Y receptor-mediated inhibition of voltage-gated Ca2+ channels.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Monophosphate; Animals; Animals, Newborn; Cadmium; Calcium Channels; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Ganglia, Sympathetic; Membrane Potentials; Membrane Proteins; Neural Inhibition; Neurons; Norepinephrine; Patch-Clamp Techniques; PC12 Cells; Pertussis Toxin; Phenethylamines; Potassium; Purine Nucleotides; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Suramin; Thionucleosides; Tritium | 2004 |
Adenosine and cAMP are potent inhibitors of the NF-kappa B pathway downstream of immunoreceptors.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; B-Lymphocytes; Cell Line; Cell Survival; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; I-kappa B Proteins; Lectins, C-Type; Lipopolysaccharides; MAP Kinase Signaling System; Mast Cells; Mice; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Receptors, Antigen, B-Cell; Receptors, IgG; Receptors, Immunologic; Signal Transduction | 2005 |
A "locked-on," constitutively active mutant of the adenosine A1 receptor.
Topics: Adenosine; Animals; Binding, Competitive; Cell Line; Cell Membrane; Chlorocebus aethiops; Colforsin; COS Cells; Cyclic AMP; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Kinetics; Mutation; Plasmids; Radioligand Assay; Receptor, Adenosine A1; Sodium; Sulfur Radioisotopes; Theophylline; Thiophenes; Transfection; Tritium; Xanthines | 2005 |
Functional expression of single-chain heterodimeric G-protein-coupled receptors for adenosine and dopamine.
Topics: Adenosine; Cell Line; Cell Membrane; Colforsin; Cyclic AMP; Dimerization; Dopamine Agonists; Drug Interactions; Fluorescent Antibody Technique, Indirect; Humans; Ligands; Models, Biological; Phenethylamines; Protein Binding; Purinergic P1 Receptor Agonists; Purinergic P2 Receptor Agonists; Quinpirole; Radioligand Assay; Receptor, Adenosine A2A; Receptors, Dopamine D2; Receptors, Purinergic P1; Receptors, Purinergic P2; Transfection | 2005 |
Lumenal adenosine and AMP rapidly increase glucose transport by intact small intestine.
Topics: 3-O-Methylglucose; Adenosine; Adenosine Monophosphate; Animals; Colforsin; Female; Glucose; Intestinal Absorption; Intestine, Small; Male; Mice; Mice, Inbred BALB C; Purinergic P1 Receptor Antagonists; Signal Transduction; Sodium-Glucose Transporter 1; Stimulation, Chemical; Theobromine; Theophylline | 2005 |
Adenosine-induced apoptosis in EL-4 thymoma cells is caspase-independent and mediated through a non-classical adenosine receptor.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenosine A2 Receptor Antagonists; Adenosine A3 Receptor Antagonists; Animals; Apoptosis; Caspase Inhibitors; Caspases; Cell Line, Tumor; Cell Survival; Colforsin; Cyclic AMP; Enzyme Activation; Membrane Potentials; Mice; Mitochondrial Membranes; Reactive Oxygen Species; Receptor, Adenosine A2B; Receptor, Adenosine A3; T-Lymphocytes; Thymoma; Thymus Neoplasms | 2005 |
Distinctive and synergistic signaling of human adenosine A2a and dopamine D2L receptors in CHO cells.
Topics: Adenosine; Adenylyl Cyclases; Animals; Antihypertensive Agents; beta-Galactosidase; Brain; Cell Line; Cell Membrane; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Dose-Response Relationship, Drug; Genes, Reporter; Green Fluorescent Proteins; Humans; Mice; Mice, Knockout; Microscopy, Fluorescence; Neurons; Pertussis Toxin; Phenethylamines; Plasmids; Receptor, Adenosine A2A; Receptors, Dopamine D2; Signal Transduction; Spectrometry, Fluorescence; Time Factors; Transfection | 2005 |
Adenosine A1 receptors mediate inhibition of cAMP formation in vitro in the pontine, REM sleep induction zone.
Topics: Adenine; Adenosine; Adenosine A1 Receptor Antagonists; Adenylyl Cyclase Inhibitors; Animals; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; In Vitro Techniques; Microinjections; Phenethylamines; Pons; Rats; Rats, Long-Evans; Receptor, Adenosine A1; Sleep, REM | 2005 |
Adenosine A2A receptors and metabotropic glutamate 5 receptors are co-localized and functionally interact in the hippocampus: a possible key mechanism in the modulation of N-methyl-D-aspartate effects.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Animals; Bicuculline; Blotting, Western; Colforsin; Disks Large Homolog 4 Protein; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Female; Fluorescent Antibody Technique; GABA Antagonists; Glycine; Hippocampus; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Phenethylamines; Phenylacetates; Pregnancy; Presynaptic Terminals; Pyridines; Qa-SNARE Proteins; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Adenosine A2; Receptors, Metabotropic Glutamate; Synaptophysin; Vesicular Glutamate Transport Protein 1 | 2005 |
Adenosine-stimulated atrial natriuretic peptide release through A1 receptor subtype.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Atrial Function; Atrial Natriuretic Factor; Colforsin; Cyclic AMP; Enzyme Inhibitors; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Xanthines | 2005 |
Adenosine A2A receptor stimulation decreases GAT-1-mediated GABA uptake in the globus pallidus of the rat.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenosine A2 Receptor Agonists; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Data Interpretation, Statistical; Enzyme Inhibitors; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Globus Pallidus; In Vitro Techniques; Isoquinolines; Male; Okadaic Acid; Phenethylamines; Rats; Rats, Wistar; Sulfonamides; Synapses; Triazines; Triazoles | 2006 |
Blockade by NIP-142, an antiarrhythmic agent, of carbachol-induced atrial action potential shortening and GIRK1/4 channel.
Topics: Action Potentials; Adenosine; Animals; Anti-Arrhythmia Agents; Atrial Function; Atropine; Bee Venoms; Benzopyrans; Carbachol; Cell Line; Colforsin; Dose-Response Relationship, Drug; Ether-A-Go-Go Potassium Channels; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Guinea Pigs; Humans; In Vitro Techniques; Myocardial Contraction; Papillary Muscles; Patch-Clamp Techniques; Potassium Channel Blockers; Time Factors | 2006 |
Adenosine opposes thrombin-induced inhibition of intercellular calcium wave in corneal endothelial cells.
Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Aniline Compounds; Animals; Calcium; Calcium Signaling; Cattle; Cells, Cultured; Colforsin; Cyclic AMP; Endothelium, Corneal; Gap Junctions; Ion Channels; Isoquinolines; Microscopy, Confocal; Myosins; Paracrine Communication; Peptide Fragments; Peptides; Phosphorylation; Receptor, Adenosine A2B; Thrombin; Xanthenes | 2007 |
Adenosine is not a direct GHSR agonist--artificial cross-talk between GHSR and adenosine receptor pathways.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine-5'-(N-ethylcarboxamide); Calcium; Cell Line; Colforsin; Cyclic AMP; Humans; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Kidney; Receptor Cross-Talk; Receptor, Adenosine A2B; Receptors, Ghrelin; Signal Transduction | 2007 |
Purinergic receptor activation inhibits mitogen-stimulated proliferation in primary neurospheres from the adult mouse subventricular zone.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cell Proliferation; Colforsin; Cyclic AMP; Mice; Mice, Inbred CBA; Neurons; Nucleotides; Protein Isoforms; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P1; Receptors, Purinergic P2; Thionucleotides; Tissue Culture Techniques | 2007 |
Adenosine inhibition of lipopolysaccharide-induced interleukin-6 secretion by the osteoblastic cell line MG-63.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Cell Line, Tumor; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Humans; Interleukin-6; Lipopolysaccharides; Osteoblasts; Osteosarcoma; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Time Factors | 2007 |
Up-regulation of adenosine A1 receptors in frontal cortex from Pick's disease cases.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Aged; Brain; Cadaver; Cell Membrane; Colforsin; Female; Frontal Lobe; Humans; Male; Occipital Lobe; Pick Disease of the Brain; Receptor, Adenosine A1; RNA, Messenger; Up-Regulation; Xanthines | 2007 |
Inhibition of erythroblast growth and fetal hemoglobin production by ribofuranose-substituted adenosine derivatives.
Topics: Adenine; Adenosine; Adult; Cell Cycle; Cell Differentiation; Cell Proliferation; Colforsin; Cyclic AMP; Deoxyadenosines; Dideoxyadenosine; Erythroblasts; Erythropoietin; Fetal Hemoglobin; Gene Expression Regulation; Gene Silencing; Globins; Humans; Kinetics; RNA, Messenger; Signal Transduction; Stem Cell Factor; Transforming Growth Factor beta | 2008 |
Adenosine analogs and electromagnetic fields inhibit prostaglandin E2 release in bovine synovial fibroblasts.
Topics: Adenosine; Animals; Binding, Competitive; Cattle; Cells, Cultured; Colforsin; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Electromagnetic Fields; Fibroblasts; Lipopolysaccharides; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; Synovial Fluid; Tumor Necrosis Factor-alpha | 2009 |
Effects of exercise training and hypercholesterolemia on adenosine activation of voltage-dependent K+ channels in coronary arterioles.
Topics: 4-Aminopyridine; Adenosine; Animals; Arterioles; Cholesterol, Dietary; Colforsin; Coronary Vessels; Hypercholesterolemia; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Physical Conditioning, Animal; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Swine; Swine, Miniature; Tetraethylammonium; Vasodilation | 2008 |
Impact of anti-inflammatory agents on the gene expression profile of stimulated human neutrophils: unraveling endogenous resolution pathways.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Colforsin; Dinoprostone; Gene Expression; Gene Expression Profiling; Humans; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligonucleotide Array Sequence Analysis; Oxytocics; Phenethylamines; Phosphodiesterase Inhibitors; Signal Transduction | 2009 |
Structure-activity relationships of truncated adenosine derivatives as highly potent and selective human A3 adenosine receptor antagonists.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Adenosine A3 Receptor Antagonists; Adenylyl Cyclases; Animals; Cell Line; CHO Cells; Colforsin; Cricetinae; Cricetulus; Furans; Humans; Purines; Receptor, Adenosine A1; Receptor, Adenosine A3; Receptors, Adenosine A2; Structure-Activity Relationship; Thionucleosides | 2009 |
Hyperglycemia accelerates impairment of vasodilator responses to acetylcholine of retinal blood vessels in rats.
Topics: Acetylcholine; Adenosine; Animals; Arterioles; Blood Pressure; Colforsin; Diabetes Mellitus, Experimental; Endothelium, Vascular; Hydroxylamines; Hyperglycemia; Immunohistochemistry; Male; Nitro Compounds; Rats; Rats, Wistar; Retinal Vessels; Severity of Illness Index; Streptozocin; Vasodilation; Vasodilator Agents | 2009 |
Reduced expression and desensitization of adenosine A1 receptor/adenylyl cyclase pathway after chronic (-)N6-phenylisopropyladenosine intake during pregnancy.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Brain; Cell Membrane; Central Nervous System Agents; Colforsin; Female; GTP-Binding Protein alpha Subunit, Gi2; GTP-Binding Protein alpha Subunits, Gi-Go; Phenylisopropyladenosine; Pregnancy; Rats; Rats, Wistar; Receptor, Adenosine A1; RNA, Messenger; Signal Transduction | 2009 |
Extracellular 3',5'-cAMP-adenosine pathway inhibits glomerular mesangial cell growth.
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Adenylyl Cyclase Inhibitors; Animals; Cell Proliferation; Cells, Cultured; Colforsin; Collagen; Cyclic AMP; DNA; Enzyme Inhibitors; Extracellular Space; Humans; Mesangial Cells; Mitogen-Activated Protein Kinases; Mitosis; Oligonucleotides, Antisense; Purinergic P1 Receptor Antagonists; Rats; Receptor, Adenosine A2B; Signal Transduction | 2010 |
Novel adenosine and cAMP signalling pathways in migrating glial cells.
Topics: Adenosine; Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Animals; Calcium; Cell Movement; Chick Embryo; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Neuroglia; Receptor, Adenosine A2B; Signal Transduction | 2010 |
Elevated cAMP opposes (TNF-alpha)-induced loss in the barrier integrity of corneal endothelium.
Topics: Actomyosin; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Blood-Retinal Barrier; Cadherins; Cattle; Colforsin; Cyclic AMP; Electric Impedance; Endothelium, Corneal; Enzyme Activation; Epithelial Cells; Intercellular Junctions; Membrane Proteins; Microtubules; p38 Mitogen-Activated Protein Kinases; Permeability; Phosphoproteins; Rolipram; Tumor Necrosis Factor-alpha; Zonula Occludens-1 Protein | 2010 |
Crosstalk between adenosine A1 and β1-adrenergic receptors regulates translocation of PKCε in isolated rat cardiomyocytes.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adrenergic beta-1 Receptor Agonists; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Intracellular Signaling Peptides and Proteins; Isoproterenol; Isoquinolines; Membrane Proteins; Myocardium; Myocytes, Cardiac; Organ Culture Techniques; Protein Kinase C-epsilon; Protein Kinase Inhibitors; Protein Transport; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptors, Adrenergic, beta-1; Signal Transduction; Sulfonamides; Xanthines | 2012 |
AMP is an adenosine A1 receptor agonist.
Topics: 5'-Nucleotidase; Adenosine; Adenosine A1 Receptor Agonists; Adenosine Monophosphate; Animals; Cerebral Cortex; Colforsin; HEK293 Cells; Histidine; Humans; Hydrolysis; Ligands; Mice; Molecular Imaging; Neurons; Receptor, Adenosine A1; Receptor, Adenosine A2B; Receptors, Purinergic P2Y; Recombinant Fusion Proteins; Single-Cell Analysis | 2012 |
Contribution of the extracellular cAMP-adenosine pathway to dual coupling of β2-adrenoceptors to Gs and Gi proteins in mouse skeletal muscle.
Topics: Adenosine; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Animals; Clenbuterol; Colforsin; Cyclic AMP; Diaphragm; Electric Stimulation; Feedback, Physiological; Fenoterol; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Male; Mice; Muscle Contraction; Receptors, Adrenergic, beta-2; Rolipram; Signal Transduction | 2012 |
Ion transport in human pancreatic duct epithelium, Capan-1 cells, is regulated by secretin, VIP, acetylcholine, and purinergic receptors.
Topics: Acetylcholine; Adenosine; Adenosine Triphosphate; Cell Line, Tumor; Colforsin; Diffusion Chambers, Culture; Epithelial Cells; Humans; Ion Transport; Ionomycin; Membrane Potentials; Pancreatic Ducts; Receptors, Purinergic P2; Secretin; Uridine Triphosphate; Vasoactive Intestinal Peptide; Vasodilator Agents | 2013 |
The P2Y(12) antagonists, 2MeSAMP and cangrelor, inhibit platelet activation through P2Y(12)/G(i)-dependent mechanism.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Blood Platelets; Cell Adhesion Molecules; Colforsin; Cyclic AMP; Epoprostenol; Mice; Mice, Knockout; Microfilament Proteins; Phosphoproteins; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Proto-Oncogene Proteins c-akt; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y; Signal Transduction; Thionucleosides | 2012 |
Proteasomal degradation of eukaryotic elongation factor-2 kinase (EF2K) is regulated by cAMP-PKA signaling and the SCFβTRCP ubiquitin E3 ligase.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Animals; Brain-Derived Neurotrophic Factor; Colforsin; Cullin Proteins; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Elongation Factor 2 Kinase; HEK293 Cells; Humans; Insulin-Like Growth Factor I; Neurons; PC12 Cells; Phenethylamines; Primary Cell Culture; Proteasome Endopeptidase Complex; Protein Binding; Protein Stability; Proteolysis; Rats; Second Messenger Systems; SKP Cullin F-Box Protein Ligases; Ubiquitination | 2013 |
Inhibition of Egr1 expression underlies the anti-mitogenic effects of cAMP in vascular smooth muscle cells.
Topics: Adenosine; Aminopyridines; Animals; Cell Proliferation; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Early Growth Response Protein 1; Epoprostenol; ets-Domain Protein Elk-1; Gene Expression Regulation; Guanine Nucleotide Exchange Factors; Human Umbilical Vein Endothelial Cells; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Organ Specificity; Primary Cell Culture; Protein Binding; rac1 GTP-Binding Protein; Rats; Rats, Sprague-Dawley; Serum Response Factor; Signal Transduction | 2014 |
Competitive mode and site of interaction of ticagrelor at the human platelet P2Y12 -receptor.
Topics: Adenosine; Adenosine Diphosphate; Animals; Binding Sites; Binding, Competitive; CHO Cells; Colforsin; Cricetulus; Cyclic AMP; Dose-Response Relationship, Drug; Gene Expression Regulation; Genes, Reporter; Humans; Luciferases; Mutation; Platelet Aggregation Inhibitors; Protein Binding; Purinergic P2Y Receptor Agonists; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Response Elements; Thionucleotides; Ticagrelor; Transfection | 2014 |
Modulation of cGMP accumulation by adenosine A1 receptors at the hippocampus: influence of cGMP levels and gender.
Topics: Adenosine; Adenosine Deaminase; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Female; Hippocampus; Imidazoles; Male; Nitroprusside; Rats; Rats, Wistar; Receptor, Adenosine A1; Rolipram; Triazines; Xanthines | 2014 |
cAMP-induced actin cytoskeleton remodelling inhibits MKL1-dependent expression of the chemotactic and pro-proliferative factor, CCN1.
Topics: Actin Cytoskeleton; Adenosine; Aminopyridines; Animals; Carotid Arteries; Cell Proliferation; Chemotaxis; Colforsin; Cyclic AMP; Cysteine-Rich Protein 61; Epoprostenol; Humans; Male; Mitogens; Models, Biological; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats, Sprague-Dawley; rho-Associated Kinases; rhoA GTP-Binding Protein; Serum Response Factor; Trans-Activators; Transcription Factors; Transcription, Genetic | 2015 |
The combined inhibitory effect of the adenosine A1 and cannabinoid CB1 receptors on cAMP accumulation in the hippocampus is additive and independent of A1 receptor desensitization.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Animals; Benzoxazines; Colforsin; Cyclic AMP; Hippocampus; Male; Morpholines; Naphthalenes; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Cannabinoid, CB1 | 2015 |
Direct visualisation of internalization of the adenosine A3 receptor and localization with arrestin3 using a fluorescent agonist.
Topics: Adenosine; Adenosine A3 Receptor Agonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Arrestins; Boron Compounds; CHO Cells; Colforsin; Cricetulus; Dose-Response Relationship, Drug; Fluorescent Dyes; Gene Expression; Ligands; Luminescent Proteins; Microscopy, Confocal; Molecular Structure; Protein Transport; Receptor, Adenosine A3; Time Factors; Transfection | 2015 |
Inhibition of PDE2A, but not PDE9A, modulates presynaptic short-term plasticity measured by paired-pulse facilitation in the CA1 region of the hippocampus.
Topics: Adenosine; Animals; CA1 Region, Hippocampal; Cadmium Chloride; Colforsin; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 2; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Long-Term Potentiation; Male; Morpholines; Neurons; Oxadiazoles; Presynaptic Terminals; Pyrimidines; Quinoxalines; Rats; Rats, Wistar | 2015 |
Inverse agonism at the P2Y12 receptor and ENT1 transporter blockade contribute to platelet inhibition by ticagrelor.
Topics: Adenosine; Adenosine Diphosphate; Blood Platelets; Calcium; Calcium Signaling; Cell Adhesion Molecules; Colforsin; Cyclic AMP; Equilibrative Nucleoside Transporter 1; Female; Humans; Male; Microfilament Proteins; Phosphoproteins; Phosphorylation; Platelet Activation; Receptors, Purinergic P2Y12; Ticagrelor | 2016 |
Alterations of ATP-sensitive K
Topics: Adenosine; Adenosine Triphosphate; Arteries; Colforsin; Cyclic AMP-Dependent Protein Kinases; Diabetes, Gestational; Female; Humans; KATP Channels; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Pinacidil; Pregnancy; Signal Transduction | 2018 |
Mechanism of luminal ATP activated chloride secretion in a polarized epithelium.
Topics: Adenosine; Adenosine Triphosphate; Animals; Calcium; Cattle; Chloride Channels; Chlorides; Colforsin; Epithelium; Female; Ion Transport; Oviducts | 2019 |
Tetanic Facilitation of Neuromuscular Transmission by Adenosine A2A and Muscarinic M1 Receptors is Dependent on the Uptake of Choline via High-Affinity Transporters.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Adenosine; Animals; Colforsin; Diaphragm; Hemicholinium 3; Membrane Transport Proteins; Neostigmine; Phenethylamines; Phrenic Nerve; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptor, Muscarinic M1; Refractory Period, Electrophysiological; Synaptic Transmission; Tetanus; Tetradecanoylphorbol Acetate | 2019 |
Adenosine and Forskolin Inhibit Platelet Aggregation by Collagen but not the Proximal Signalling Events.
Topics: Adenosine; Adenosine Monophosphate; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Blood Platelets; Carrier Proteins; Cells, Cultured; Colforsin; Collagen; Cyclic AMP; Feedback, Physiological; Humans; Indomethacin; Peptides; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptor, Adenosine A2A; Signal Transduction; Thromboxane B2 | 2019 |
Participation of the adenosine salvage pathway and cyclic AMP modulation in oocyte energy metabolism.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Bucladesine; Coculture Techniques; Colforsin; Cumulus Cells; Cyclic AMP; Energy Metabolism; Female; Gap Junctions; Gene Expression; In Vitro Oocyte Maturation Techniques; Meiosis; Mice; Oocytes | 2019 |
Chemicals orchestrate reprogramming with hierarchical activation of master transcription factors primed by endogenous Sox17 activation.
Topics: Adenosine; Animals; Benzoates; Bone Morphogenetic Proteins; Cell Lineage; Cellular Reprogramming; Chalcones; Colforsin; Endoderm; Fibroblasts; Gene Expression Regulation; HMGB Proteins; Mice, Inbred ICR; Phenylurea Compounds; Pyridines; Pyrimidines; Single-Cell Analysis; SOXF Transcription Factors; Tetrahydronaphthalenes; Transcription Factors | 2020 |
A1 Adenosine Receptor Activation Inhibits P2X3 Receptor-Mediated ATP Currents in Rat Dorsal Root Ganglion Neurons.
Topics: Adenosine; Adenosine Triphosphate; Adenylyl Cyclases; Analgesics; Animals; Colforsin; Ganglia, Spinal; Neurons; Pain; Pertussis Toxin; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Receptors, Purinergic P1; Receptors, Purinergic P2X3 | 2022 |