adenosine has been researched along with 3-deazaadenosine in 59 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (49.15) | 18.7374 |
| 1990's | 17 (28.81) | 18.2507 |
| 2000's | 9 (15.25) | 29.6817 |
| 2010's | 2 (3.39) | 24.3611 |
| 2020's | 2 (3.39) | 2.80 |
| Authors | Studies |
|---|---|
| Cristalli, G; Esker, JL; Jacobson, KA; Ji, XD; Melman, N; Olah, ME; Schneller, SW; Secrist, JA; Siddiqi, SM; Tiwari, KN | 1 |
| Antonini, I; Cristalli, G; Franchetti, P; Grifantini, M; Lupidi, G; Martelli, S; Riva, F | 1 |
| Clayton, SJ; Montgomery, JA; Secrist, JA | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Bayle, ED; Fish, PV; Li, F; Schapira, M; Spurr, SS; Tempel, W; Vedadi, M; Yu, W | 1 |
| Ackerman, JJ; Buttz, HR; Duerre, JA | 1 |
| Bozzi, A; Corbo, RM; Ingianna, R; Scacchi, R | 1 |
| Doherty, NS; Gieske, TH; Raddatz, R; Stephens, D | 1 |
| Aarbakke, J; Bang, BE; Endresen, PC; Møller, C; Prytz, PS | 1 |
| Cerný, J; Holý, A; Hrebabecký, H; Merta, A; Otmar, M; Rosenberg, I; Sedivá, K; Veselý, J; Vlach, J; Votruba, I | 1 |
| Cristalli, G; Eleuteri, A; Franchetti, P; Grifantini, M; Lupidi, G; Vittori, S | 1 |
| Fischer, AA; Müller, K; Scholtissek, C | 1 |
| Ledoux, DN; Smith, JD | 1 |
| Aarbakke, J; Prytz, PS | 1 |
| Aswad, DW; Najbauer, J | 1 |
| Church, MK; Hughes, PJ; Vardey, CJ | 1 |
| Dalaker, K; Prydz, H | 1 |
| Benyon, RC; Church, MK; Hughes, PJ | 1 |
| Lefort, J; Randon, J; Vargaftig, BB | 1 |
| Aarbakke, J; Loennechen, T; Prytz, PS | 1 |
| Chaffee, S; Greenberg, ML; Hershfield, MS | 1 |
| Djurhuus, R; Svardal, AM; Ueland, PM | 1 |
| Henson, PM; Riches, DW; Stanworth, DR; Watkins, JL | 1 |
| Liteplo, RG | 1 |
| Finbloom, DS; Gordon, RK; Martin, J | 1 |
| Djurhuus, R; Svardal, A; Ueland, PM | 1 |
| Backlund, PS; Cantoni, GL; Carotti, D | 1 |
| Kufe, DW; Shafman, TD; Sherman, ML; Spriggs, DR | 1 |
| Lappin, D; Whaley, K | 1 |
| Chiang, PK; Morita, Y; Siraganian, RP | 1 |
| Morita, Y; Siraganian, RP | 1 |
| Benyon, RC; Church, MK; Holgate, ST | 1 |
| Mizel, D; Pick, E | 1 |
| Aksamit, RR; Backlund, PS | 1 |
| Bergstrom, DE; De Clercq, E; Holy, A; Montgomery, JA | 1 |
| Aksamit, RR; Backlund, PS; Bozzi, A; Cantoni, GL; Chen, J; Scarpa, S; Strom, R | 1 |
| Cantoni, GL; Chiang, PK; Kim, IK; Zhang, CY | 1 |
| Chiang, PK | 1 |
| Ueland, PM | 1 |
| Chiang, PK; Garcia-Castro, I; Mato, JM; Schiffmann, E; Vasanthakumar, G; Wiesmann, WP | 1 |
| Aksamit, RR; Backlund, PS; Cantoni, GL | 1 |
| Chiang, PK; Montgomery, JA; Shattil, SJ | 1 |
| Linder, M; Scholtissek, C; Woyciniuk, P | 1 |
| Imoto, M; Kawada, M; Masuoka, S; Mizutani, Y; Umezawa, K | 1 |
| Aarbakke, J; Endresen, PC; Kildalsen, H; Loennechen, T | 1 |
| Cheong, CH; Hong, SH; Jeong, SY; Kim, HS; Kim, IK; Lee, JH | 1 |
| Loennechen, T; Svendsrud, DH; Winberg, JO | 1 |
| Umezawa, K | 1 |
| Ashizawa, K; Miyamoto, M; Tsuzuki, Y | 1 |
| Muth, GW; Ortoleva-Donnelly, L; Strobel, SA | 1 |
| Jeong, SW; Jeong, SY; Kim, BE; Kim, HS; Kim, IK; Kim, JW; Lee, JH | 1 |
| Chiang, CH; Perng, WC; Wu, CP; Yan, HC; Yu, CP | 1 |
| Chen, YF; Li, PL; Zou, AP | 1 |
| Bujnicki, JM; Caridha, D; Chiang, PK; Prigge, ST | 1 |
| Afman, LA; Blom, HJ; Brouns, MR; Drittij, MJ; van Straaten, HW | 1 |
| Bea, F; Blessing, E; Isermann, B; Katus, HA; Kreuzer, J; Pedal, I; Preusch, MR; Rosenfeld, ME; Yang, SH | 1 |
| Cho, JY; Hong, S; Kim, HG; Kim, JH; Kim, KH; Kim, SC; Lee, JY; Yang, WS; Yang, Y; Yi, YS; Yoo, BC | 1 |
| Chen, Q; Chen, T; Chen, X; Gong, A; Liang, R; Mathy, NW; Tian, K; Xu, J; Yu, T | 1 |
| Jia, G; Li, Y; Luo, GZ; Peng, W; Qi, S; Wang, K; Wang, M; Wang, X; Wang, Y; Wu, L; Xiao, Y; Xue, X; Zhao, L | 1 |
2 review(s) available for adenosine and 3-deazaadenosine
| Article | Year |
|---|---|
Chemotaxis and methylation in a macrophage cell line.
Topics: Adenine; Adenosine; Animals; Blood Proteins; Cell Line; Chemotaxis, Leukocyte; Guinea Pigs; Humans; Macrophages; Methylation; Mice; Phosphatidylethanolamines; Rabbits; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin | 1983 |
Pharmacological and biochemical aspects of S-adenosylhomocysteine and S-adenosylhomocysteine hydrolase.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Catalysis; Chemical Phenomena; Chemistry, Physical; Genes; Homocysteine; Humans; Hydrolases; Kinetics; Protein Binding; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; S-Adenosylhomocysteine; Substrate Specificity; Tubercidin | 1982 |
57 other study(ies) available for adenosine and 3-deazaadenosine
| Article | Year |
|---|---|
Search for new purine- and ribose-modified adenosine analogues as selective agonists and antagonists at adenosine receptors.
Topics: Adenosine; Animals; Cell Membrane; CHO Cells; Corpus Striatum; Cricetinae; In Vitro Techniques; Magnetic Resonance Spectroscopy; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Radioligand Assay; Rats; Recombinant Proteins; Ribose; Structure-Activity Relationship | 1995 |
Adenosine deaminase inhibitors. Synthesis of deaza analogues of erythro-9-(2-hydroxy-3-nonyl)adenine.
Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Cattle; Intestines; Nucleoside Deaminases | 1984 |
(+/-)-3-(4-Amino-1H-pyrrolo[2,3-d]pyrimidin-1-yl)-5-(hydroxymethyl)- (1 alpha,2 alpha,3 beta,5 beta)-1,2-cyclopentanediol, the carbocyclic analogue of tubercidin.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Carcinoma, Squamous Cell; Cell Line; Humans; Indicators and Reagents; Laryngeal Neoplasms; Leukemia L1210; Magnetic Resonance Spectroscopy; Mice; Ribonucleosides; Structure-Activity Relationship; Tubercidin | 1984 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
New small molecule inhibitors of histone methyl transferase DOT1L with a nitrile as a non-traditional replacement for heavy halogen atoms.
Topics: Crystallography; Enzyme Inhibitors; Halogens; Histone-Lysine N-Methyltransferase; Methyltransferases; Nitriles; Small Molecule Libraries; Structure-Activity Relationship | 2016 |
Effect of methylation inhibitors on gene expression in HL-60 cells.
Topics: Adenosine; Cell Differentiation; Gene Expression Regulation, Neoplastic; Genes, myc; Humans; Methylation; Poly A; RNA, Messenger; RNA, Neoplasm; Tretinoin; Tubercidin; Tumor Cells, Cultured | 1992 |
Kinetic properties of the common electrophoretic variants of human S-adenosylhomocysteine hydrolase (AHCY): the effect of four nucleoside analogue inhibitors.
Topics: 2-Chloroadenosine; Adenosine; Adenosylhomocysteinase; Anti-Bacterial Agents; Enzyme Inhibitors; Erythrocytes; Humans; Hydrolases; Isomerism; Kinetics; Purine Nucleosides; Ribonucleosides; Tubercidin | 1992 |
S-adenosylhomocysteine levels are not involved in the spasmolytic activity of 3-deazaadenosine in guinea-pig lung parenchyma.
Topics: Adenosine; Animals; Cyclic AMP; Cyclic GMP; Guinea Pigs; Homocysteine; In Vitro Techniques; Lung; Male; Parasympatholytics; S-Adenosylhomocysteine; SRS-A; Tubercidin | 1991 |
Elevation of cyclic AMP levels in HL-60 cells accumulated in G1 or G2 by transmethylation inhibitors.
Topics: Adenosine; Cell Division; Cell Line; Cyclic AMP; Flow Cytometry; G1 Phase; G2 Phase; Homocysteine; Humans; Leukemia; Methyltransferases; Tubercidin | 1991 |
Acyclic nucleotide analogues: synthesis, antiviral activity and inhibitory effects on some cellular and virus-encoded enzymes in vitro.
Topics: Adenine; Adenosine; Antiviral Agents; Cidofovir; Cytosine; DNA Viruses; Guanine; In Vitro Techniques; Nucleic Acid Synthesis Inhibitors; Nucleotides; Organophosphonates; Organophosphorus Compounds; Purine-Nucleoside Phosphorylase; Reverse Transcriptase Inhibitors; Ribonucleotide Reductases; Structure-Activity Relationship; Tubercidin | 1990 |
Adenosine deaminase inhibitors: synthesis and structure-activity relationships of imidazole analogues of erythro-9-(2-hydroxy-3-nonyl)adenine.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Aminoimidazole Carboxamide; Animals; Binding Sites; Cattle; Chemical Phenomena; Chemistry; Intestines; Molecular Structure; Structure-Activity Relationship; Tubercidin | 1991 |
Specific inhibition of the synthesis of influenza virus late proteins and stimulation of early, M2, and NS2 protein synthesis by 3-deazaadenosine.
Topics: Adenosine; Aminoglycosides; Animals; Anti-Bacterial Agents; Capsid; Cell Line; Cells, Cultured; Chick Embryo; Enzyme Inhibitors; Influenza A virus; Isomerism; Kinetics; Mice; RNA, Messenger; RNA, Viral; Tubercidin; Viral Core Proteins; Viral Nonstructural Proteins; Viral Proteins; Virus Replication | 1990 |
Effect of the methylation inhibitors 3-deazaadenosine and 3-deazaaristeromycin on phosphatidylcholine formation in Tetrahymena.
Topics: Adenosine; Animals; Carbon Radioisotopes; Choline; Enzyme Inhibitors; Isomerism; Kinetics; Methionine; Phosphatidylcholines; Tetrahymena; Tritium; Tubercidin | 1990 |
Differential cell cycle perturbation by transmethylation inhibitors.
Topics: Adenosine; Adenosylhomocysteinase; Aminoglycosides; Anti-Bacterial Agents; Cell Cycle; Enzyme Inhibitors; Flow Cytometry; Humans; Hydrolases; Interphase; Kinetics; Leukemia, Promyelocytic, Acute; Methylation; Mitosis; Tubercidin; Tumor Cells, Cultured | 1990 |
Diversity of methyl acceptor proteins in rat pheochromocytoma (PC12) cells revealed after treatment with adenosine dialdehyde.
Topics: Adenosine; Adrenal Gland Neoplasms; Animals; Deoxyadenosines; Electrophoresis, Gel, Two-Dimensional; Methylation; Molecular Weight; Neoplasm Proteins; Nerve Tissue Proteins; Pheochromocytoma; Rats; S-Adenosylmethionine; Thionucleosides; Tubercidin; Tumor Cells, Cultured | 1990 |
Studies on the receptor mediating cyclic AMP-independent enhancement by adenosine of IgE-dependent mediator release from rat mast cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenine Nucleotides; Adenosine; Animals; Cyclic AMP; Dose-Response Relationship, Drug; Immunoglobulin E; In Vitro Techniques; Male; Mast Cells; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Serotonin; Tachyphylaxis; Theophylline; Time Factors; Tubercidin | 1986 |
Effect of some drugs on thromboplastin activity in mouse trophoblast cells in vitro and in vivo.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenosine; Animals; Calcium Channel Blockers; Dinoprostone; Felodipine; Female; Gallic Acid; Methylation; Mice; Monensin; Nifedipine; Nitrendipine; Pregnancy; Prostaglandins E; Thromboplastin; Trophoblasts; Tubercidin; Verapamil | 1986 |
Adenosine inhibits immunoglobulin E-dependent histamine secretion from human basophil leukocytes by two independent mechanisms.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Basophils; Cyclic AMP; Dipyridamole; Dose-Response Relationship, Drug; Histamine Release; Humans; Immunoglobulin E; Methylation; Phospholipids; S-Adenosylmethionine; Theophylline; Tubercidin | 1987 |
Blockade by methylation inhibitors of the anaphylactic response of guinea-pig lung strips.
Topics: Adenosine; Airway Resistance; Anaphylaxis; Animals; Female; Guinea Pigs; Histamine Release; Homocysteine; In Vitro Techniques; Lung; Male; Methylation; Ovalbumin; Thromboxane B2; Tubercidin | 1987 |
DNA-methylation in HL-60 cells treated with 3-deaza-(+/-)-aristeromycin and 3-deazaadenosine.
Topics: 5-Methylcytosine; Adenosine; Aminoglycosides; Anti-Bacterial Agents; Cell Count; Cell Line; Chromatography, High Pressure Liquid; Cytosine; DNA; Enzyme Inhibitors; Humans; Stereoisomerism; Tubercidin | 1989 |
Basis for resistance to 3-deazaaristeromycin, an inhibitor of S-adenosylhomocysteine hydrolase, in human B-lymphoblasts.
Topics: Adenosine; Adenosylhomocysteinase; B-Lymphocytes; Cell Line; Clone Cells; Drug Resistance; Enzyme Inhibitors; Humans; Hydrolases; Isomerism; Kinetics; Tubercidin | 1989 |
Differential effects on growth, homocysteine, and related compounds of two inhibitors of S-adenosylhomocysteine catabolism, 3-deazaadenosine, and 3-deazaaristeromycin, in C3H/10T1/2 cells.
Topics: Adenosine; Aminoglycosides; Animals; Anti-Bacterial Agents; Cell Division; Cell Line; Dose-Response Relationship, Drug; Glutathione; Glutathione Disulfide; Homocysteine; Mice; Mice, Inbred C3H; S-Adenosylhomocysteine; Tubercidin | 1989 |
Regulation of macrophage lysosomal secretion by adenosine, adenosine phosphate esters, and related structural analogues of adenosine.
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Esterases; Homocysteine; Kinetics; Lysosomes; Macrophages; Male; Mice; Receptors, Cell Surface; Receptors, Purinergic; Secretory Rate; Structure-Activity Relationship; Theophylline; Tubercidin | 1985 |
DNA (cytosine) methylation in murine and human tumor cell lines treated with S-adenosylhomocysteine hydrolase inhibitors.
Topics: Adenosine; Adenosylhomocysteinase; Animals; DNA, Neoplasm; Humans; Hydrolases; Methylation; Mice; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin; Tumor Cells, Cultured | 1988 |
Endocytosis of particulate and soluble IgG immune complexes: differential effects of cytoskeletal modulating agents.
Topics: Adenosine; Animals; Antigen-Antibody Complex; Colchicine; Cytochalasin B; Cytoskeleton; Endocytosis; Immunoglobulin G; Methylation; Mice; Mice, Inbred C3H; Phospholipids; Tubercidin | 1987 |
Disposition of homocysteine and S-3-deazaadenosylhomocysteine in cells exposed to 3-deazaadenosine.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Fibroblasts; Homocysteine; Hydrolases; Liver; Mice; Neoplasms, Experimental; Protein Binding; Rats; Ribonucleosides; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin | 1986 |
Effects of the S-adenosylhomocysteine hydrolase inhibitors 3-deazaadenosine and 3-deazaaristeromycin on RNA methylation and synthesis.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Cells, Cultured; Hydrolases; Methylation; Ribonucleosides; RNA, Messenger; S-Adenosylhomocysteine; Tubercidin | 1986 |
Inhibition of murine erythroleukemia cell differentiation by 3-deazaadenosine.
Topics: Adenosine; Adenosylmethionine Decarboxylase; Animals; Cell Differentiation; Cell Line; Deoxyadenosines; Dimethyl Sulfoxide; DNA; Leukemia, Erythroblastic, Acute; Methylation; Mice; Ribonucleosides; S-Adenosylhomocysteine; S-Adenosylmethionine; Thionucleosides; Tubercidin | 1985 |
Adenosine A2 receptors on human monocytes modulate C2 production.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Complement C2; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Immunosuppressive Agents; Monocytes; Phenylisopropyladenosine; Receptors, Cell Surface; Receptors, Purinergic; Tubercidin | 1984 |
Effect of inhibitors of transmethylation on histamine release from human basophils.
Topics: Adenine; Adenosine; Basophils; Calcimycin; Histamine Release; Homocysteine; Humans; Immunoglobulin E; In Vitro Techniques; Methylation; Ribonucleosides; S-Adenosylmethionine; Tubercidin | 1981 |
Inhibition of IgE-mediated histamine release from rat basophilic leukemia cells and rat mast cells by inhibitors of transmethylation.
Topics: Adenine; Adenosine; Animals; Basophils; Female; Histamine Release; Homocysteine; Immunoglobulin E; Leukemia; Mast Cells; Methylation; Mice; Rabbits; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin | 1981 |
The effect of methyltransferase inhibitors on histamine release from human dispersed lung mast cells activated with anti-human IgE and calcium ionophore A23187.
Topics: Adenine; Adenosine; Antibodies, Anti-Idiotypic; Calcimycin; Histamine Release; Humans; Immunoglobulin E; Mast Cells; Membrane Lipids; Methylation; Methyltransferases; Phospholipids; Ribonucleosides; S-Adenosylmethionine; Tubercidin | 1984 |
Role of transmethylation in the elicitation of an oxidative burst in macrophages.
Topics: Adenosine; Animals; Concanavalin A; Depression, Chemical; Guinea Pigs; Homocysteine; Lectins; Macrophage Activation; Macrophages; Methylation; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Oxygen; Superoxides; Tubercidin; Wheat Germ Agglutinins | 1982 |
Broad-spectrum antiviral activity of adenosine analogues.
Topics: Adenosine; Antiviral Agents; Structure-Activity Relationship; Tubercidin; Viruses | 1984 |
Differentiation of myoblast cell lines and biological methylation: 3-deazaadenosine stimulates formation of multinucleated myofibers.
Topics: Adenosine; Animals; Animals, Newborn; Cell Differentiation; Cell Line; Clone Cells; Creatine Kinase; DNA; Enzyme Inhibitors; Isomerism; Muscles; Rats; Ribonucleosides; Tubercidin | 1984 |
S-Adenosylhomocysteine hydrolase from hamster liver: purification and kinetic properties.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Cricetinae; Female; Hydrolases; Isomerism; Kinetics; Liver; Mesocricetus; Molecular Weight; Tubercidin | 1983 |
S-adenosylhomocysteine hydrolase as a pharmacological target for the inhibition of transmethylation.
Topics: Adenosine; Animals; Enzyme Inhibitors; Homocysteine; Isomerism; Kinetics; Mice; Ribonucleosides; S-Adenosylhomocysteine; Structure-Activity Relationship; Tubercidin | 1984 |
Paradoxical effects of adenosine on neutrophil chemotaxis.
Topics: Adenosine; Animals; Chemotaxis, Leukocyte; Isomerism; Kinetics; Neutrophils; Phospholipids; Rabbits; Tubercidin | 1983 |
Chemotaxis and the synthesis of specific proteins are inhibited by 3-deazaadenosine and other adenosine analogs in a mouse macrophage cell line.
Topics: Adenosine; Animals; Cell Line; Chemotaxis; Cycloheximide; Dactinomycin; Isomerism; Macrophages; Mice; Protein Biosynthesis; Puromycin; Ribonucleosides; Structure-Activity Relationship; Tubercidin | 1983 |
The effect of pharmacologic inhibition of phospholipid methylation on human platelet function.
Topics: Adenosine; Adenosylhomocysteinase; Blood Platelets; Humans; Hydrolases; Methylation; Phosphatidylethanolamines; Phospholipids; Platelet Aggregation; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin | 1982 |
The methyltransferase inhibitor Neplanocin A interferes with influenza virus replication by a mechanism different from that of 3-deazaadenosine.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Chick Embryo; Drug Synergism; Homocysteine; Hydrolases; Influenza A virus; Methionine; Methyltransferases; RNA Caps; RNA, Viral; S-Adenosylhomocysteine; Tubercidin; Viral Proteins; Virus Replication | 1995 |
Induction of erythroid differentiation in leukaemic K562 cells by an S-adenosylhomocysteine hydrolase inhibitor, aristeromycin.
Topics: 3T3 Cells; Adenosine; Adenosylhomocysteinase; Animals; Cell Differentiation; Cell Division; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Formycins; Genes, abl; Humans; Hydrolases; Isomerism; Kinetics; Leukemia, Erythroblastic, Acute; Mice; Tubercidin; Tumor Cells, Cultured | 1995 |
Apoptosis and transmethylation metabolites in HL-60 cells.
Topics: Adenosine; Apoptosis; DNA; DNA Fragmentation; Enzyme Inhibitors; HL-60 Cells; Homocysteine; Humans; Methylation; Methyltransferases; Nucleic Acid Synthesis Inhibitors; RNA; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin | 1996 |
3-Deazaadenosine analogues inhibit the production of tumour necrosis factor-alpha in RAW264.7 cells stimulated with lipopolysaccharide.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Cell Line; Depression, Chemical; Hydrolases; Interleukin-1; Isomerism; Lipopolysaccharides; Macrophages; Mice; Protein Biosynthesis; Transcription, Genetic; Tubercidin; Tumor Necrosis Factor-alpha | 1996 |
Effect of adenosine analogues on the expression of matrix metalloproteinases and their inhibitors from human dermal fibroblasts.
Topics: Adenosine; Adenosylhomocysteinase; Cell Survival; Cells, Cultured; Collagenases; DNA Fragmentation; Enzyme Inhibitors; Fibroblasts; Gelatinases; Glycoproteins; Humans; Hydrolases; Matrix Metalloproteinase 3; Matrix Metalloproteinase Inhibitors; Metalloendopeptidases; Protease Inhibitors; Skin; Tissue Inhibitor of Metalloproteinases; Tubercidin | 1997 |
Induction of cellular differentiation and apoptosis by signal transduction inhibitors.
Topics: Adenosine; Animals; Antineoplastic Agents; Apoptosis; Cell Differentiation; Cell Division; Formycins; Gene Expression Regulation, Neoplastic; Genes, abl; Humans; Hydroquinones; Molecular Structure; Neoplasms; Protein Tyrosine Phosphatases; Signal Transduction; Tubercidin; Tumor Cells, Cultured | 1997 |
The possible role of protein-carboxyl methylation in the regulation of flagellar movement of fowl spermatozoa.
Topics: Adenosine; Adenosine Triphosphate; Animals; Calcium Chloride; Chickens; Enzyme Inhibitors; Homocysteine; Luminescent Measurements; Male; Marine Toxins; Methylation; Oxazoles; Proteins; Semen; Sperm Motility; Sperm Tail; Tubercidin | 2000 |
A single adenosine with a neutral pKa in the ribosomal peptidyl transferase center.
Topics: Adenosine; Binding Sites; Catalysis; Dimethyl Sulfoxide; Escherichia coli; Hydrogen Bonding; Methylation; Mutation; Peptide Biosynthesis; Peptidyl Transferases; Protons; Ribosomes; RNA, Bacterial; RNA, Ribosomal, 23S; Tubercidin | 2000 |
Induction of apoptosis in human leukemia cells by 3-deazaadenosine is mediated by caspase-3-like activity.
Topics: Adenosine; Apoptosis; Biological Transport, Active; Carrier Proteins; Caspase 3; Caspases; Down-Regulation; Enzyme Activation; Genes, myc; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Thioinosine; Transcription Factors; Tubercidin; U937 Cells | 2000 |
Use of anti-(tumour necrosis factor-alpha) antibody or 3-deaza-adenosine as additives to promote protection by University of Wisconsin solution in ischaemia/reperfusion injury.
Topics: Adenosine; Allopurinol; Animals; Antibodies, Monoclonal; Glutathione; Hemodynamics; Insulin; Lung; Lung Transplantation; Male; Organ Culture Techniques; Organ Preservation; Organ Preservation Solutions; Organ Size; Raffinose; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tubercidin; Tumor Necrosis Factor-alpha | 2000 |
Effect of hyperhomocysteinemia on plasma or tissue adenosine levels and renal function.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Fluorescence; Hemodynamics; Homocysteine; Hydrolases; Hyperhomocysteinemia; Kidney; Rats; Rats, Sprague-Dawley; Reference Standards; Risk Factors; Tubercidin | 2002 |
Structure, evolution, and inhibitor interaction of S-adenosyl-L-homocysteine hydrolase from Plasmodium falciparum.
Topics: Adenosine; Adenosylhomocysteinase; Amino Acid Sequence; Animals; Binding Sites; Cloning, Molecular; DNA, Protozoan; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Evolution, Molecular; Hydrolases; Kinetics; Models, Molecular; Molecular Sequence Data; Phylogeny; Plasmodium falciparum; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Sequence Alignment; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Substrate Specificity; Tubercidin | 2003 |
Inhibition of transmethylation disturbs neurulation in chick embryos.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Chick Embryo; Cycloleucine; Dose-Response Relationship, Drug; Drug Interactions; Embryonic Development; Homocysteine; Methylation; Models, Biological; Nervous System; Organogenesis; S-Adenosylhomocysteine; Time Factors; Tubercidin | 2005 |
Long-term administration of 3-deazaadenosine does not alter progression of advanced atherosclerotic lesions in apolipoprotein E-deficient mice.
Topics: Actins; Adenosine; Animals; Aorta, Thoracic; Apolipoproteins E; Atherosclerosis; Disease Models, Animal; Electrophoretic Mobility Shift Assay; Female; Homocysteine; Intercellular Adhesion Molecule-1; Interleukin-10; Interleukin-1beta; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Transcription Factor AP-1; Tubercidin; Vascular Cell Adhesion Molecule-1 | 2007 |
Adenosine dialdehyde suppresses MMP-9-mediated invasion of cancer cells by blocking the Ras/Raf-1/ERK/AP-1 signaling pathway.
Topics: Adenosine; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Coenzyme A Ligases; Humans; MAP Kinase Signaling System; Matrix Metalloproteinase 9; MCF-7 Cells; Methylation; Phosphorylation; Protein Methyltransferases; Proto-Oncogene Proteins c-raf; ras Proteins; RNA, Small Interfering; Signal Transduction; Transcription Factor AP-1; Tubercidin | 2013 |
m6A methyltransferase METTL3 maintains colon cancer tumorigenicity by suppressing SOCS2 to promote cell proliferation.
Topics: Adenosine; Aged; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Colectomy; Colon; Colonic Neoplasms; Datasets as Topic; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Gene Knockout Techniques; Humans; Male; Methylation; Methyltransferases; Middle Aged; Neoplasm Staging; Receptors, G-Protein-Coupled; RNA Stability; RNA, Messenger; Spheroids, Cellular; Suppressor of Cytokine Signaling Proteins; Tubercidin | 2020 |
RNA m
Topics: Adenosine; Animals; Bees; Cell Differentiation; Female; Gene Expression Regulation, Developmental; Larva; Methylation; RNA; RNA Processing, Post-Transcriptional; Signal Transduction; Transcriptome; Tubercidin; Vitellogenins | 2021 |