Page last updated: 2024-09-03

adenosine amine congener and n(6)-cyclopentyladenosine

adenosine amine congener has been researched along with n(6)-cyclopentyladenosine in 4 studies

Compound Research Comparison

Studies
(adenosine amine congener)
Trials
(adenosine amine congener)
Recent Studies (post-2010)
(adenosine amine congener)
Studies
(n(6)-cyclopentyladenosine)
Trials
(n(6)-cyclopentyladenosine)
Recent Studies (post-2010) (n(6)-cyclopentyladenosine)
2905605062

Protein Interaction Comparison

ProteinTaxonomyadenosine amine congener (IC50)n(6)-cyclopentyladenosine (IC50)
Adenosine receptor A1Rattus norvegicus (Norway rat)0.2256
Adenosine receptor A2bRattus norvegicus (Norway rat)1.16
Adenosine receptor A1Homo sapiens (human)0.0027
Adenosine receptor A2aRattus norvegicus (Norway rat)1.16

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Berkich, DA; Dean, RL; Eveleth, D; Hiramatsu, K; Jacobson, KA; Ji, XD; Kassell, NF; Lee, KS; Nikodijevic, O; van Galen, PJ1
Jacobson, KA; van Galen, PJ; Williams, M1
Deflorian, F; Gao, ZG; Jacobson, KA; Jiang, X; Moss, SM; Paoletta, S; Phan, K; Tosh, DK1
Bivalacqua, TJ; Champion, HC; Kadowitz, PJ; Lambert, DG1

Reviews

1 review(s) available for adenosine amine congener and n(6)-cyclopentyladenosine

ArticleYear
Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential.
    Journal of medicinal chemistry, 1992, Feb-07, Volume: 35, Issue:3

    Topics: Adenosine; Animals; Humans; Models, Chemical; Receptors, Purinergic; Second Messenger Systems; Structure-Activity Relationship

1992

Other Studies

3 other study(ies) available for adenosine amine congener and n(6)-cyclopentyladenosine

ArticleYear
Synthesis and biological activity of N6-(p-sulfophenyl)alkyl and N6-sulfoalkyl derivatives of adenosine: water-soluble and peripherally selective adenosine agonists.
    Journal of medicinal chemistry, 1992, Oct-30, Volume: 35, Issue:22

    Topics: Adenosine; Animals; Body Temperature; Brain; Evoked Potentials; Gerbillinae; In Vitro Techniques; Lipolysis; Male; Mice; Motor Activity; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Solubility; Structure-Activity Relationship; Sulfonic Acids

1992
Structural sweet spot for A1 adenosine receptor activation by truncated (N)-methanocarba nucleosides: receptor docking and potent anticonvulsant activity.
    Journal of medicinal chemistry, 2012, Sep-27, Volume: 55, Issue:18

    Topics: Animals; Anticonvulsants; CHO Cells; Cricetinae; Cricetulus; Humans; Male; Mice; Molecular Docking Simulation; Nucleosides; Protein Conformation; Receptor, Adenosine A1; Structure-Activity Relationship

2012
Vasodilator responses to adenosine and hyperemia are mediated by A(1) and A(2) receptors in the cat vascular bed.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2002, Volume: 282, Issue:6

    Topics: Adenosine; Adenosine Triphosphate; Animals; Cats; Dose-Response Relationship, Drug; Female; Hemodynamics; Hindlimb; Hyperemia; Male; Perfusion; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Receptors, Purinergic P1; Triazoles; Vascular Resistance; Vasodilation; Xanthines

2002