Page last updated: 2024-09-03

adenosine amine congener and adenosine

adenosine amine congener has been researched along with adenosine in 18 studies

Compound Research Comparison

Studies
(adenosine amine congener)
Trials
(adenosine amine congener)
Recent Studies (post-2010)
(adenosine amine congener)
Studies
(adenosine)
Trials
(adenosine)
Recent Studies (post-2010) (adenosine)
290532,5361,0758,930

Protein Interaction Comparison

ProteinTaxonomyadenosine amine congener (IC50)adenosine (IC50)
high affinity choline transporter 1 isoform aHomo sapiens (human)0.3851
Sodium/nucleoside cotransporter 1Homo sapiens (human)5.5
Sodium/nucleoside cotransporter 2Homo sapiens (human)5.5
Adenosine receptor A3Homo sapiens (human)0.0011
Adenosine receptor A1Homo sapiens (human)0.0023
Equilibrative nucleoside transporter 1Homo sapiens (human)63
Solute carrier family 28 member 3Homo sapiens (human)3.3

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (38.89)18.2507
2000's9 (50.00)29.6817
2010's2 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Berkich, DA; Dean, RL; Eveleth, D; Hiramatsu, K; Jacobson, KA; Ji, XD; Kassell, NF; Lee, KS; Nikodijevic, O; van Galen, PJ1
Balcells, E; Rubio, R; Suarez, J1
Beenhakker, M; Bischofberger, N; Carter, MF; Jacobson, KA; Lin, RC; Paul, IA; Von Lubitz, DK1
Beenhakker, M; Bischofberger, N; Boyd, M; Jacobson, KA; Lin, RC; Paul, IA; Von Lubitz, DK1
Kim, YH; Song, DK; Suh, HW1
Bischofberger, N; Jacobson, KA; von Lubitz, DK1
Beenhakker, M; Bischofberger, N; Boyd, M; Jacobson, KA; Lin, RC; Lipartowska, R; Von Lubitz, DK1
Adén, U; Fredholm, BB; Hagberg, H; Leverin, AL1
Bivalacqua, TJ; Champion, HC; Kadowitz, PJ; Lambert, DG1
Fowler, JC; Gervitz, LM; Hamilton, ME; Lutherer, LO1
Ceballos, G; Rubio, R1
Bantubungi, K; Blum, D; d'Alcantara, P; Galas, MC; Gall, D; Schiffmann, SN1
Henry, S; Noorbakhsh, F; Power, C; Schnermann, J; Tsutsui, S; Warren, K; Winston, BW; Yong, VW1
Karlik, SJ; Messersmith, E; Meyer-Franke, A; Roscoe, WA; Wipke, B1
Barrett, CJ; Bennet, L; Booth, LC; Gunn, AJ; Jensen, EC; Malpas, SC; Tummers, L1
Civan, MM; Do, CW; Karl, MO; Leung, CT; Li, A; Macknight, AD; McLaughlin, CW; Stone, RA; Wang, Z; Zellhuber-McMillan, S1
Chang, H; Chi, HH; Housley, GD; Paek, SY; Sreebhavan, S; Telang, RS; Thorne, PR; Tingle, M; Vlajkovic, SM1
Chang, H; Sreebhavan, S; Telang, RS; Thorne, PR; Tingle, M; Vlajkovic, SM1

Reviews

1 review(s) available for adenosine amine congener and adenosine

ArticleYear
Adenosine A1 receptor agonists as clinically viable agents for treatment of ischemic brain disorders.
    Annals of the New York Academy of Sciences, 1997, Oct-15, Volume: 825

    Topics: Adenosine; Animals; Brain; Brain Ischemia; Cell Survival; Humans; Ischemic Attack, Transient; Neurons; Neuroprotective Agents; Purinergic P1 Receptor Agonists

1997

Other Studies

17 other study(ies) available for adenosine amine congener and adenosine

ArticleYear
Synthesis and biological activity of N6-(p-sulfophenyl)alkyl and N6-sulfoalkyl derivatives of adenosine: water-soluble and peripherally selective adenosine agonists.
    Journal of medicinal chemistry, 1992, Oct-30, Volume: 35, Issue:22

    Topics: Adenosine; Animals; Body Temperature; Brain; Evoked Potentials; Gerbillinae; In Vitro Techniques; Lipolysis; Male; Mice; Motor Activity; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Solubility; Structure-Activity Relationship; Sulfonic Acids

1992
Functional role of intravascular coronary endothelial adenosine receptors.
    European journal of pharmacology, 1992, Jan-07, Volume: 210, Issue:1

    Topics: Adenosine; Animals; Atrioventricular Node; Coronary Circulation; Coronary Vessels; Endothelium, Vascular; Glycogen; Guinea Pigs; Heart Rate; Latex; Male; Microspheres; Myocardial Contraction; Receptors, Purinergic; Vascular Resistance; Ventricular Function

1992
Reduction of postischemic brain damage and memory deficits following treatment with the selective adenosine A1 receptor agonist.
    European journal of pharmacology, 1996, Apr-29, Volume: 302, Issue:1-3

    Topics: Adenosine; Analysis of Variance; Animals; Behavior, Animal; Brain Ischemia; Female; Gerbillinae; Maze Learning; Memory; Motor Activity; Purinergic P1 Receptor Agonists

1996
Postischemic administration of adenosine amine congener (ADAC): analysis of recovery in gerbils.
    European journal of pharmacology, 1996, Dec-05, Volume: 316, Issue:2-3

    Topics: Adenosine; Animals; Brain Ischemia; Cell Survival; Female; Gerbillinae; Hippocampus; Immunohistochemistry; Prognosis

1996
Differential effects of adenosine receptor antagonists injected intrathecally on antinociception induced by morphine and beta-endorphin administered intracerebroventricularly in the mouse.
    Neuropeptides, 1997, Volume: 31, Issue:4

    Topics: Adenosine; Analgesics; Animals; beta-Endorphin; Dose-Response Relationship, Drug; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Morphine; Phenethylamines; Purinergic P1 Receptor Antagonists; Reaction Time; Theobromine; Xanthines

1997
Protection against ischemic damage by adenosine amine congener, a potent and selective adenosine A1 receptor agonist.
    European journal of pharmacology, 1999, Mar-26, Volume: 369, Issue:3

    Topics: Adenosine; Analysis of Variance; Animals; Brain Ischemia; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Gerbillinae; Hippocampus; Injections, Intraperitoneal; Purinergic P1 Receptor Agonists

1999
Adenosine A(1) receptor agonism in the immature rat brain and heart.
    European journal of pharmacology, 2001, Aug-31, Volume: 426, Issue:3

    Topics: Adenosine; Animals; Animals, Newborn; Binding, Competitive; Body Temperature; Brain; Brain Ischemia; Dose-Response Relationship, Drug; Female; Guanosine 5'-O-(3-Thiotriphosphate); Heart; Heart Rate; Hypoxia; Iodine Radioisotopes; Male; Myocardium; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Rectum; Sulfur Radioisotopes; Time Factors; Xanthines

2001
Vasodilator responses to adenosine and hyperemia are mediated by A(1) and A(2) receptors in the cat vascular bed.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2002, Volume: 282, Issue:6

    Topics: Adenosine; Adenosine Triphosphate; Animals; Cats; Dose-Response Relationship, Drug; Female; Hemodynamics; Hindlimb; Hyperemia; Male; Perfusion; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Receptors, Purinergic P1; Triazoles; Vascular Resistance; Vasodilation; Xanthines

2002
Lack of central effects of peripherally administered adenosine A(1) agonists on synaptic transmission in the rat hippocampus.
    Brain research, 2002, Sep-27, Volume: 951, Issue:1

    Topics: Adenosine; Animals; Cardiovascular Physiological Phenomena; Excitatory Postsynaptic Potentials; Hippocampus; Hypoxia-Ischemia, Brain; Male; Neurons; Neuroprotective Agents; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Synapses; Synaptic Transmission; Theophylline

2002
Sole activation of three luminal adenosine receptor subtypes in different parts of coronary vasculature.
    American journal of physiology. Heart and circulatory physiology, 2003, Volume: 284, Issue:1

    Topics: Adenosine; Animals; Aorta; Coronary Vessels; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; Heart; In Vitro Techniques; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Perfusion; Phenethylamines; Polymers; Protein Isoforms; Purinergic P1 Receptor Agonists; Receptors, Purinergic P1; Vasoconstriction; Vasodilation

2003
The adenosine A1 receptor agonist adenosine amine congener exerts a neuroprotective effect against the development of striatal lesions and motor impairments in the 3-nitropropionic acid model of neurotoxicity.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Oct-15, Volume: 22, Issue:20

    Topics: Adenosine; Animals; Behavior, Animal; Binding, Competitive; Body Weight; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Dystonia; Enkephalins; Hindlimb; Huntington Disease; In Vitro Techniques; Male; Mitochondria; Motor Activity; Neuroprotective Agents; Neurotoxins; Nitro Compounds; Propionates; Purinergic P1 Receptor Agonists; Rats; Rats, Inbred Lew; Reproducibility of Results; RNA, Messenger; Succinate Dehydrogenase; Synaptic Transmission; Treatment Outcome

2002
A1 adenosine receptor upregulation and activation attenuates neuroinflammation and demyelination in a model of multiple sclerosis.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Feb-11, Volume: 24, Issue:6

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Animals; Caffeine; Disease Models, Animal; Disease Progression; Encephalomyelitis, Autoimmune, Experimental; Female; Humans; Inflammation; Inflammation Mediators; Interleukin-1; Macrophages; Matrix Metalloproteinase 12; Metalloendopeptidases; Mice; Mice, Knockout; Microglia; Multiple Sclerosis; Myelin Sheath; Phenotype; Receptor, Adenosine A1; Recurrence; RNA, Messenger; Severity of Illness Index; Spinal Cord; Up-Regulation

2004
Connexin 43 gap junction proteins are up-regulated in remyelinating spinal cord.
    Journal of neuroscience research, 2007, Volume: 85, Issue:5

    Topics: Adenosine; Animals; Antibodies; Connexin 43; Connexins; Encephalomyelitis, Autoimmune, Experimental; Female; Guinea Pigs; Integrin alpha4; Myelin Sheath; Nerve Regeneration; Recovery of Function; Spinal Cord; Up-Regulation

2007
Differential effects of the adenosine A1 receptor agonist adenosine amine congener on renal, femoral and carotid vascular conductance in preterm fetal sheep.
    Clinical and experimental pharmacology & physiology, 2008, Volume: 35, Issue:11

    Topics: Adenosine; Animals; Carotid Arteries; Female; Femoral Artery; Fetus; Pregnancy; Premature Birth; Regional Blood Flow; Renal Circulation; Sheep, Domestic

2008
Electron probe X-ray microanalysis of intact pathway for human aqueous humor outflow.
    American journal of physiology. Cell physiology, 2008, Volume: 295, Issue:5

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Aqueous Humor; Cell Size; Chlorides; Electron Probe Microanalysis; Enzyme Inhibitors; Feasibility Studies; Humans; Hypotonic Solutions; Intraocular Pressure; Norbornanes; Osmotic Pressure; Ouabain; Phenethylamines; Phosphorus; Potassium; Receptor, Adenosine A1; Receptors, Adenosine A2; Sodium; Sodium-Potassium-Exchanging ATPase; Trabecular Meshwork

2008
Adenosine amine congener as a cochlear rescue agent.
    BioMed research international, 2014, Volume: 2014

    Topics: Adenosine; Animals; Cochlea; Dose-Response Relationship, Drug; Evoked Potentials, Auditory, Brain Stem; Hearing Loss, Noise-Induced; Injections, Intraperitoneal; Injections, Intravenous; Male; Protective Agents; Rats; Rats, Wistar

2014
Pharmacokinetic Properties of Adenosine Amine Congener in Cochlear Perilymph after Systemic Administration.
    BioMed research international, 2017, Volume: 2017

    Topics: Adenosine; Animals; Cochlea; Hearing Loss, Noise-Induced; Male; Perilymph; Rats; Rats, Wistar

2017