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adenosine 5'-o-(1-thiodiphosphate) and adenosine diphosphate

adenosine 5'-o-(1-thiodiphosphate) has been researched along with adenosine diphosphate in 22 studies

Compound Research Comparison

Studies
(adenosine 5'-o-(1-thiodiphosphate))
Trials
(adenosine 5'-o-(1-thiodiphosphate))
Recent Studies (post-2010)
(adenosine 5'-o-(1-thiodiphosphate))
Studies
(adenosine diphosphate)
Trials
(adenosine diphosphate)
Recent Studies (post-2010) (adenosine diphosphate)
230323,9894983,114

Protein Interaction Comparison

ProteinTaxonomyadenosine 5'-o-(1-thiodiphosphate) (IC50)adenosine diphosphate (IC50)
Chain A, Kinesin-like protein KIF11Homo sapiens (human)0.45
Heat shock 70 kDa protein 1A Homo sapiens (human)0.5
Sensor protein kinase WalKStaphylococcus aureus7.189

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19909 (40.91)18.7374
1990's7 (31.82)18.2507
2000's3 (13.64)29.6817
2010's3 (13.64)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bhave, DP; Carroll, KS; Hong, JA1
Azran, S; Danino, O; Dixit, M; Fischer, B; Förster, D; Kenigsberg, S; Major, DT; Reiser, G; Singh, V1
Baraniak, J; Kaczmarek, R; Korczyński, D; Krakowiak, A; Nawrot, B1
Cooper, CL; Harden, TK; Jeffs, RA1
Goodhart, PJ; LoBrutto, R; Reed, GH; Sammons, RD; Smithers, GW1
Cusack, NJ; Pearson, JD1
Bhatnagar, D; Carlson, GM; Cheng, A; Fitzgerald, TJ; Roskoski, R1
Carlson, GM; Cheng, A1
Cusack, NJ; Hourani, SM2
Goody, RS; Hofman, W; Konrad, M1
Benkovic, SJ; Marlier, JF1
Benkovic, SJ; Bryant, FR; Marlier, JF1
Dahnke, T; Jiang, RT; Shi, Z; Tsai, MD1
Momose, K; Ohata, H; Ujike, Y1
Kadenbach, B; Napiwotzki, J; Shinzawa-Itoh, K; Yoshikawa, S1
Haas, CA; Kreutzberg, GW; Priller, J; Reddington, M1
Blayac, JP; Chapal, J; Hillaire-Buys, D; Linck, N; Loubatières-Mariani, MM; Petit, P1
Hourani, SM; Park, HS1
Conigrave, AD; Luttrell, BM; Morris, MB; Rakyan, V; van der Weyden, L1
Allgaier, C; Barsoumian, EL; Draheim, H; Franke, H; Gerevich, Z; Illes, P; Schweigel, J; Wirkner, K1
Bringmann, A; Chen, J; Färber, K; Grosse, J; Illes, P; Krügel, U; Linnertz, R; Lipp, S; Pannicke, T; Reichenbach, A; Schöneberg, T; Schulz, A; Wiedemann, P; Wurm, A; Zahn, D1

Other Studies

22 other study(ies) available for adenosine 5'-o-(1-thiodiphosphate) and adenosine diphosphate

ArticleYear
Identification of critical ligand binding determinants in Mycobacterium tuberculosis adenosine-5'-phosphosulfate reductase.
    Journal of medicinal chemistry, 2009, Sep-10, Volume: 52, Issue:17

    Topics: Catalytic Domain; Drug Design; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Ligands; Magnesium; Models, Molecular; Mycobacterium tuberculosis; Oxidoreductases Acting on Sulfur Group Donors; Pseudomonas aeruginosa; Static Electricity; Substrate Specificity

2009
Identification of Highly Promising Antioxidants/Neuroprotectants Based on Nucleoside 5'-Phosphorothioate Scaffold. Synthesis, Activity, and Mechanisms of Action.
    Journal of medicinal chemistry, 2015, Nov-12, Volume: 58, Issue:21

    Topics: Animals; Antioxidants; Cells, Cultured; Drug Discovery; Humans; Hydrogen Peroxide; Hydrolysis; Iron; Models, Molecular; Neurons; Neuroprotective Agents; Nucleosides; Nucleotides; PC12 Cells; Phosphorothioate Oligonucleotides; Purinergic P2Y Receptor Agonists; Rats; Reactive Oxygen Species; Receptors, Purinergic P2Y1

2015
Phosphorothioate analogs of P1,P3-di(nucleosid-5'-yl) triphosphates: Synthesis, assignment of the absolute configuration at P-atoms and P-stereodependent recognition by Fhit hydrolase.
    Bioorganic & medicinal chemistry, 2016, 11-01, Volume: 24, Issue:21

    Topics: Acid Anhydride Hydrolases; Humans; Kinetics; Neoplasm Proteins; Polyphosphates; Stereoisomerism

2016
Solubilization of a guanine nucleotide-sensitive form of the P2Y-purinergic receptor.
    Molecular pharmacology, 1991, Volume: 40, Issue:1

    Topics: Adenine; Adenosine Diphosphate; Animals; Digitonin; Erythrocyte Membrane; GTP-Binding Proteins; Guanine Nucleotides; Kinetics; Molecular Weight; Receptors, Purinergic; Solubility; Sulfur Radioisotopes; Thionucleotides; Turkeys

1991
Stereochemical control over Mn(II)-thio versus Mn(II)-oxy coordination in adenosine 5'-O-(1-thiodiphosphate) complexes at the active site of creatine kinase.
    Biochemistry, 1989, Feb-21, Volume: 28, Issue:4

    Topics: Adenosine Diphosphate; Animals; Binding Sites; Creatine Kinase; Electron Spin Resonance Spectroscopy; Kinetics; Magnesium; Manganese; Molecular Conformation; Muscles; Rabbits; Substrate Specificity; Thionucleotides

1989
Investigation of the preferred Mg(II)-adenine-nucleotide complex at the active site of ectonucleotidases in intact vascular cells using phosphorothioate analogues of ADP and ATP.
    European journal of biochemistry, 1985, Sep-02, Volume: 151, Issue:2

    Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Aorta; Binding Sites; Blood Vessels; Cells, Cultured; Magnesium; Muscle, Smooth, Vascular; Nucleotidases; Stereoisomerism; Swine; Thionucleotides

1985
Allosteric nucleotide specificity of phosphorylase kinase: correlation of binding, conformational transitions, and activation. Utilization of lin-benzo-ADP to measure the binding of other nucleoside diphosphates, including the phosphorothioates of ADP.
    The Journal of biological chemistry, 1988, Apr-25, Volume: 263, Issue:12

    Topics: Adenosine Diphosphate; Allosteric Regulation; Allosteric Site; Animals; Enzyme Activation; Magnesium; Muscles; Nucleotides; Phosphorylase Kinase; Protein Binding; Protein Conformation; Rabbits; Thionucleotides

1988
Competition between nucleoside diphosphates and triphosphates at the catalytic and allosteric sites of phosphorylase kinase.
    The Journal of biological chemistry, 1988, Apr-25, Volume: 263, Issue:12

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Allosteric Site; Animals; Binding Sites; Binding, Competitive; Enzyme Activation; Guanosine Diphosphate; Guanosine Triphosphate; Hydrogen-Ion Concentration; Muscles; Nucleotides; Phosphorylase Kinase; Rabbits; Thionucleotides

1988
Differential inhibition by adenosine or by prostaglandin E1 of human platelet aggregation induced by adenosine 5'-O-(1-thiodiphosphate) and adenosine 5'-O-(2-thiodiphosphate).
    British journal of pharmacology, 1982, Volume: 75, Issue:2

    Topics: Adenosine Diphosphate; Alprostadil; Humans; In Vitro Techniques; Platelet Aggregation; Prostaglandins E; Thionucleotides

1982
On the structure of the myosin-ADP-mg complex.
    FEBS letters, 1981, Jun-29, Volume: 129, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Binding Sites; Cadmium; Chromium; Cobalt; Magnesium; Myosin Subfragments; Myosins; Peptide Fragments; Rabbits; Stereoisomerism; Thionucleotides

1981
On the mechanism of de novo polymerization by form I polynucleotide phosphorylase of Micrococcus luteus.
    Biochemistry, 1982, May-11, Volume: 21, Issue:10

    Topics: Adenosine Diphosphate; Binding Sites; Kinetics; Micrococcus; Molecular Weight; Poly A; Polymers; Polyribonucleotide Nucleotidyltransferase; Stereoisomerism; Substrate Specificity; Thionucleotides

1982
Stereochemical and kinetic investigation of 32P-labeled inorganic phosphate exchange reaction catalyzed by primer-independent and primer-dependent polynucleotide phosphorylase from Micrococcus luteus.
    Biochemistry, 1981, Apr-14, Volume: 20, Issue:8

    Topics: Adenosine Diphosphate; Kinetics; Micrococcus; Molecular Conformation; Phosphates; Polyribonucleotide Nucleotidyltransferase; Structure-Activity Relationship; Substrate Specificity; Thionucleotides

1981
Effects of RP and SP diastereoisomers of adenosine 5'-O-(1-thiodiphosphate) on human platelets.
    British journal of pharmacology, 1981, Volume: 73, Issue:2

    Topics: Adenosine Diphosphate; Adenylyl Cyclases; Blood Platelets; Humans; In Vitro Techniques; Nucleotides; Platelet Aggregation; Prostaglandins H; Stereoisomerism; Thionucleotides

1981
Manipulating phosphorus stereospecificity of adenylate kinase by site-directed mutagenesis.
    Methods in enzymology, 1995, Volume: 249

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenylate Kinase; Binding Sites; Molecular Probes; Mutagenesis, Site-Directed; Stereoisomerism; Substrate Specificity; Thionucleotides

1995
Confocal imaging analysis of ATP-induced Ca2+ response in individual endothelial cells of the artery in situ.
    The American journal of physiology, 1997, Volume: 272, Issue:6 Pt 1

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aniline Compounds; Animals; Aorta, Thoracic; Calcium; Egtazic Acid; Endothelium, Vascular; Fluorescent Dyes; Guinea Pigs; In Vitro Techniques; Kinetics; Microscopy, Confocal; Muscle, Smooth, Vascular; Receptors, Purinergic P2; Thionucleotides; Uridine Triphosphate; Xanthenes

1997
ATP and ADP bind to cytochrome c oxidase and regulate its activity.
    Biological chemistry, 1997, Volume: 378, Issue:9

    Topics: Adenosine Diphosphate; Animals; Binding Sites; Cattle; Cholic Acids; Crystallization; Dialysis; Electron Transport Complex IV; Liver; Myocardium; Polarography; Polysorbates; Protein Conformation; Spectrophotometry, Ultraviolet; Sulfur Radioisotopes; Thionucleotides

1997
Stimulation of P2Y-purinoceptors on astrocytes results in immediate early gene expression and potentiation of neuropeptide action.
    Neuroscience, 1998, Volume: 85, Issue:2

    Topics: Adenosine Diphosphate; Animals; Animals, Newborn; Astrocytes; Calcitonin Gene-Related Peptide; Cells, Cultured; Cyclic AMP; DNA-Binding Proteins; Drug Synergism; Gene Expression Regulation; Genes, fos; Genes, Immediate-Early; Genes, jun; Immediate-Early Proteins; Neuropeptides; Proteins; Rats; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; RNA, Messenger; Tetradecanoylphorbol Acetate; Thionucleotides; Tristetraprolin

1998
Involvement of K+ channel permeability changes in the L-NAME and indomethacin resistant part of adenosine-5'-O-(2-thiodiphosphate)-induced relaxation of pancreatic vascular bed.
    British journal of pharmacology, 1998, Volume: 124, Issue:1

    Topics: Adenosine Diphosphate; Animals; Apamin; Blood Vessels; Charybdotoxin; Enzyme Inhibitors; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Ouabain; Pancreas; Potassium; Potassium Channels; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Thionucleotides; Tolbutamide; Vasoconstrictor Agents; Vasodilator Agents

1998
Differential effects of adenine nucleotide analogues on shape change and aggregation induced by adnosine 5-diphosphate (ADP) in human platelets.
    British journal of pharmacology, 1999, Volume: 127, Issue:6

    Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Blood Platelets; Cell Size; Dose-Response Relationship, Drug; Humans; Platelet Aggregation; Suramin; Thionucleotides; Trypanocidal Agents; Uridine Triphosphate

1999
Extracellular ATP couples to cAMP generation and granulocytic differentiation in human NB4 promyelocytic leukaemia cells.
    Immunology and cell biology, 2000, Volume: 78, Issue:5

    Topics: 1-Methyl-3-isobutylxanthine; Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Antigens, CD; Blotting, Northern; Cell Differentiation; Cell Size; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activation; Granulocytes; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Phosphodiesterase Inhibitors; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Receptors, Purinergic P2; Reverse Transcriptase Polymerase Chain Reaction; Thionucleotides; Tretinoin; Tumor Cells, Cultured

2000
Adenine nucleotides inhibit recombinant N-type calcium channels via G protein-coupled mechanisms in HEK 293 cells; involvement of the P2Y13 receptor-type.
    British journal of pharmacology, 2004, Volume: 141, Issue:1

    Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium Channels, N-Type; Calcium Signaling; Cell Line; Dose-Response Relationship, Drug; GTP-Binding Proteins; Humans; Membrane Proteins; Patch-Clamp Techniques; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rabbits; Receptors, G-Protein-Coupled; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Thionucleotides; Transfection

2004
Endogenous purinergic signaling is required for osmotic volume regulation of retinal glial cells.
    Journal of neurochemistry, 2010, Volume: 112, Issue:5

    Topics: 5'-Nucleotidase; Adenine; Adenosine Diphosphate; Animals; Barium Compounds; Calcium; Cell Size; Chlorides; Cyclic AMP; Drug Combinations; Enzyme Inhibitors; In Vitro Techniques; Inositol 1,4,5-Trisphosphate Receptors; Mice; Mice, Knockout; Neuroglia; Neurons; Osmolar Concentration; Osmosis; Potassium Channel Blockers; Purinergic Agonists; Purinergic Antagonists; Pyrimidine Nucleotides; Quaternary Ammonium Compounds; Receptors, Purinergic; Retina; Signal Transduction; Thionucleotides; Time Factors; Valerates; Xanthines

2010