adenosine 5'-methylenediphosphate has been researched along with adenosine in 85 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (15.29) | 18.7374 |
| 1990's | 31 (36.47) | 18.2507 |
| 2000's | 25 (29.41) | 29.6817 |
| 2010's | 14 (16.47) | 24.3611 |
| 2020's | 2 (2.35) | 2.80 |
| Authors | Studies |
|---|---|
| Bhave, DP; Carroll, KS; Hong, JA | 1 |
| Späth, L; Starke, K; von Kügelgen, I | 1 |
| Berne, RM; Headrick, JP; Matherne, GP | 1 |
| Cunha, RA; Sebastião, AM | 1 |
| Borst, MM; Schrader, J | 1 |
| Cahill, BE; Haile, DM; Kadowitz, PJ; Neely, CF | 1 |
| Chen, G; Suzuki, H | 1 |
| Kather, H | 1 |
| Belardinelli, L; Boykin, MT; Hill, JA; Shryock, JC | 1 |
| Deussen, A; Möser, GH; Schrader, J | 1 |
| Chin, WP; Imai, S; Jin, H; Nakazawa, M | 1 |
| Berne, RM; Meghji, P; Rubio, R | 1 |
| Fraser, LR; Monks, NJ | 1 |
| Bukoski, RD; Sparks, HV | 1 |
| Cartner, LA; Holliss, DG; Humphrey, SM | 1 |
| Ehinger, BE; Fredholm, BB; Lindström, K; Perez, MT | 1 |
| Fuchs, BD; Gorman, MW; Sparks, HV | 1 |
| Belloni, FL; Elkin, PL; Giannotto, B | 1 |
| Chapal, J; Loubatières-Mariani, MM; Roye, M; Zerbib, A | 1 |
| Fredholm, BB; Jonzon, B; Lindgren, E; Lindström, K | 1 |
| Maire, JC; Medilanski, J; Straub, RW | 1 |
| Kille, JM; Klabunde, RE | 1 |
| Downey, HF; Fan, WL; Gao, ZP; Mallet, RT | 1 |
| Starke, K; Stoffel, D; von Kügelgen, I | 1 |
| Hori, M; Itoh, T; Iwakura, K; Kitakaze, M; Komamura, K; Minamino, T; Morioka, T; Node, K; Okazaki, Y; Takashima, S | 1 |
| Hassinen, IE; Peuhkurinen, KJ; Raatikainen, MJ | 1 |
| Chujo, M; Hori, M; Inoue, M; Kitakaze, M; Minamino, T; Mori, H; Morioka, T; Sato, H; Shinozaki, Y; Takashima, S | 1 |
| Fredholm, BB; Lindström, K; Lloyd, HG | 1 |
| Franklin, PH; Murray, TF; Zhang, G | 1 |
| Bengtsson, T; Grenegård, M; Stendahl, O; Zalavary, S | 1 |
| Culic, O; Lemmens, R; Teuchy, H; Vanduffel, L | 1 |
| Cunha, RA; Ribeiro, JA; Sebastião, AM; Vizi, ES | 1 |
| Marshall, JM; Skinner, MR | 1 |
| Hori, M; Inoue, M; Kamada, T; Kitakaze, M; Komamura, K; Minamino, T; Node, K | 1 |
| Berleth, ES; Ehrke, MJ; Kitano, H; Mihich, E; Pietkiewicz, JM; Skaar, JR; Ujházy, P | 1 |
| Burnstock, G; Spyer, KM; St Lambert, JH; Thomas, T | 1 |
| Funaya, H; Hori, M; Kitakaze, M; Minamino, T; Mori, H; Node, K; Shinozaki, Y | 1 |
| Koch, H; Starke, K; von Kügelgen, I | 1 |
| Brause, M; Delabar, U; Eckardt, KU; Gleiter, CH; Zebski, H | 1 |
| Oliveira, CR; Rego, AC; Santos, MS | 1 |
| Arita, M; Obata, T; Sato, T; Yamanaka, Y | 1 |
| Hendrickson, WA; Klein, MG; Lima, CD | 1 |
| Brundege, JM; Diao, L; Dunwiddie, TV; Proctor, WR | 1 |
| Asanuma, H; Funaya, H; Hori, M; Kitakaze, M; Kuzuya, T; Minamino, T; Sato, H; Ueda, Y | 1 |
| Habuchi, Y; Morikawa, J; Nishio, M; Tanaka, H; Yamamoto, T | 1 |
| Brendel, P; Cunha, RA; Ribeiro, JA; Zimmermann, H | 1 |
| Obata, T; Yamanaka, Y | 1 |
| Nikbakht, MR; Stone, TW | 1 |
| Belardinelli, L; Erga, KS; Liang, HX; Seubert, CN; Shryock, JC; Wu, L | 1 |
| Matsuki, N; Nakazawa, K; Ohno, Y; Sato, K | 1 |
| Kimura, J; Matsuoka, I; Ohkubo, S | 1 |
| Geiger, JD; Mackiewicz, M; Pack, AI | 1 |
| Boegehold, MA; Sauls, BA | 1 |
| Chen, YF; Li, PL; Zou, AP | 1 |
| Bültmann, R; Klebroff, W; Starke, K | 1 |
| Imamura, H; Kido, M; Lu, K; Ninomiya, H; Otani, H; Uchiyama, T | 1 |
| Hasebe, N; Jin, YT; Kawabe, J; Kikuchi, K; Matsusaka, T | 1 |
| Mihaylova-Todorova, ST; Todorov, LD; Westfall, DP | 1 |
| Bulmer, D; Dale, N; Gourine, AV; Llaudet, E; Spyer, KM; Thomas, T | 1 |
| Bernard, EA; de Souza, LF; Gelain, DP | 1 |
| Huang, MH; Liu, SI; Wu, SN | 1 |
| Conde, SV; Monteiro, EC | 1 |
| Hellsten, Y; Jensen, L; Schjerling, P | 1 |
| Liu, XJ; Parkinson, FE; Reid, AR; Sawynok, J | 1 |
| Chen, S; Ma, D; Ou, Z; Shao, Z; Wang, L; Yin, L; Zhi, X; Zhou, P; Zhou, T; Zhou, X | 1 |
| Eckle, T; Eltzschig, HK; Gleiter, CH; Grenz, A; Kloor, D; Köhle, C; Osswald, H; Schnermann, J; Vallon, V; von Wietersheim, S; Weingart, J; Zhang, H | 1 |
| Eltzschig, HK; Gorzolla, IC; Hart, ML; Henn, M; Kloor, D; Köhler, D; Mittelbronn, M; Stahl, GL | 1 |
| Caldwell, CC; Lentsch, AB | 1 |
| Mohlin, C; Nilsson, M; Persson, K; Säve, S | 1 |
| Antonilli, L; Brusadin, V; Catalano, M; Chece, G; Cipriani, R; Eusebi, F; Fredholm, BB; Lauro, C; Limatola, C; Trettel, F; van Rooijen, N | 1 |
| Curiel, TJ; Fan, J; Shin, T; Thompson, LF; Wang, L; Zhang, B; Zhang, Y | 1 |
| Boeck, CR; Calo', G; de Andrade, VM; Gavioli, EC; Guerrini, R; Mendonça, BP; Pacheco, R; Pescador, BB; Ramos, SF | 1 |
| Barrios, CH; Bavaresco, L; Bueno Morrone, F; Cappellari, AR; Fernandes Farias, P; Oliveira Battastini, AM; Rockenbach, L | 1 |
| Liu, W; Lovatt, D; Nedergaard, M; Schnermann, J; Smith, NA; Takano, T; Tieu, K; Xu, Q | 1 |
| Gillespie, DG; Jackson, EK | 1 |
| El-Tayeb, A; Knapp, K; Müller, CE; Pippel, J; Sträter, N; Zebisch, M | 1 |
| Brown, KM; Ham, A; Kim, KY; Kim, M; Lee, HT | 1 |
| Bogo, MR; Bonan, CD; Capiotti, KM; da Costa Schaefer, I; Da Silva, RS; Frantz, JZ; Kist, LW; Menezes, FP; Siebel, AM | 1 |
| Cristóvão, G; Cunha, RA; George, J; Gomes, CA; Gonçalves, FQ; Gonçalves, T; Meyer Fernandes, JR; Rodrigues, L | 1 |
| Eichin, D; Jalkanen, S; Laurila, JP; Salmi, M | 1 |
| Alam, MS; Cavanaugh, C; Costales, MG; Williams, KM | 1 |
| Deppen, J; García, AJ; Levit, RD; Shin, EY; Strobel, F; Tirouvanziam, R; Wang, L; Xu, K; Zemskova, M | 1 |
| Agostinho, P; Andrade, GM; Canas, PM; Carmo, M; Cunha, RA; Duarte, FV; Fernandes, FD; Gonçalves, FQ; Oses, JP; Palmeira, CM; Tomé, AR | 1 |
| Bai, X; Liu, P; Zhou, L; Zhu, L | 1 |
| Da Silva, RS; Lutte, AH; Majolo, JH | 1 |
85 other study(ies) available for adenosine 5'-methylenediphosphate and adenosine
| Article | Year |
|---|---|
Identification of critical ligand binding determinants in Mycobacterium tuberculosis adenosine-5'-phosphosulfate reductase.
Topics: Catalytic Domain; Drug Design; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Ligands; Magnesium; Models, Molecular; Mycobacterium tuberculosis; Oxidoreductases Acting on Sulfur Group Donors; Pseudomonas aeruginosa; Static Electricity; Substrate Specificity | 2009 |
Stable adenine nucleotides inhibit [3H]-noradrenaline release in rabbit brain cortex slices by direct action at presynaptic adenosine A1-receptors.
Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cerebral Cortex; Drug Interactions; Drug Stability; Electric Stimulation; Female; Male; Nerve Endings; Norepinephrine; Purinergic Antagonists; Rabbits; Receptors, Purinergic; Suramin; Synapses; Theophylline; Tritium; Xanthines | 1992 |
Myocardial adenosine formation during hypoxia: effects of ecto-5'-nucleotidase inhibition.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Guinea Pigs; Heart; Hypoxia; In Vitro Techniques; Male; Myocardium; Perfusion; Vascular Resistance | 1992 |
Extracellular metabolism of adenine nucleotides and adenosine in the innervated skeletal muscle of the frog.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cations; Coformycin; Dipyridamole; In Vitro Techniques; Inosine Monophosphate; Kinetics; Muscles; Piperazines; Rana ridibunda; Sodium-Potassium-Exchanging ATPase; Thioinosine | 1991 |
Adenine nucleotide release from isolated perfused guinea pig hearts and extracellular formation of adenosine.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Coronary Disease; Extracellular Space; Female; Guinea Pigs; Hemodynamics; Isoproterenol; Myocardium; Oxygen; Partial Pressure; Perfusion | 1991 |
Adenosine and ATP produce vasoconstriction in the feline pulmonary vascular bed by different mechanisms.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cats; Cyclooxygenase Inhibitors; Fatty Acids, Unsaturated; Hydrazines; Lung; Meclofenamic Acid; Phenylisopropyladenosine; Purinergic Antagonists; Receptors, Prostaglandin; Receptors, Purinergic; Receptors, Thromboxane; Thromboxane A2; Vasoconstriction; Vasodilator Agents; Xanthines | 1991 |
Endothelium-dependent hyperpolarization elicited by adenine compounds in rabbit carotid artery.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Calcium; Carotid Arteries; Cell Membrane; Electrophysiology; Endothelium, Vascular; Kinetics; Male; Membrane Potentials; Rabbits | 1991 |
Pathways of purine metabolism in human adipocytes. Further evidence against a role of adenosine as an endogenous regulator of human fat cell function.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Kinase; Adenosine Monophosphate; Adenosine Triphosphate; Adipose Tissue; Glycerophosphates; Humans; Hypoxanthine; Hypoxanthines; Inosine; Inosine Monophosphate; Isoproterenol; Lipolysis; Pentostatin; Purines; Tubercidin | 1990 |
A new method of sampling blood for measurement of plasma adenosine.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Blood Specimen Collection; Carbon Radioisotopes; Catheterization; Dipyridamole; Humans | 1990 |
Turnover of adenosine in plasma of human and dog blood.
Topics: 5'-Nucleotidase; Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosylhomocysteinase; Animals; Blood Flow Velocity; Dipyridamole; Dogs; Forearm; Half-Life; Humans; Hydrolases; Nucleotidases; Tritium | 1989 |
Production of AMP and adenosine in the interstitial fluid compartment of the isolated perfused normoxic guinea pig heart.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Extracellular Space; Guinea Pigs; Heart; Hydroxydopamines; Inosine; Male; Myocardium; Oxidopamine; Pyrophosphatases; Sympathectomy, Chemical | 1989 |
Intracellular adenosine formation and its carrier-mediated release in cultured embryonic chick heart cells.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Biological Transport; Carrier Proteins; Cells, Cultured; Chick Embryo; Deoxyglucose; Dilazep; Dipyridamole; Heart; Hexobendine; Membrane Proteins; Myocardium; Nucleoside Transport Proteins; Nucleotidases; Nucleotides; Oligomycins; Oxygen | 1988 |
Inhibition of adenosine-metabolizing enzymes modulates mouse sperm fertilizing ability: a changing role for endogenously generated adenosine during capacitation.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Coformycin; Fertilization; Fertilization in Vitro; Male; Mice; Nucleotidases; Sperm Capacitation | 1988 |
Adenosine production and release by adult rat cardiocytes.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Biological Transport, Active; Dinitrophenols; Dipyridamole; Heart; In Vitro Techniques; Iodoacetates; Iodoacetic Acid; Myocardium; Nucleotidases; Rats; Rats, Inbred Strains; Thioinosine | 1986 |
The influence of inhibitors of the ATP degradative pathway on recovery of function and high energy phosphate after transient ischemia in the rat heart.
Topics: 5'-Nucleotidase; Acute Disease; Adenine; Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Triphosphate; Adenylate Kinase; Animals; Coronary Circulation; Coronary Disease; Dinucleoside Phosphates; Male; Nucleotidases; Rats; Rats, Inbred Strains; Thioinosine | 1986 |
Release of endogenous and radioactive purines from the rabbit retina.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Animals; Dipyridamole; Evoked Potentials; Female; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Male; Potassium; Purines; Rabbits; Retina; Tritium | 1986 |
Adenosine release into venous plasma during free flow exercise.
Topics: Adenosine; Adenosine Diphosphate; Animals; Chromatography, High Pressure Liquid; Dogs; Electric Stimulation; Isoproterenol; Male; Oxygen Consumption; Physical Exertion; Veins | 1986 |
The mechanism of adenosine release from hypoxic rat liver cells.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Dipyridamole; Liver; Oxygen; Rats; Thioinosine | 1985 |
Effects of adenosine, adenosine triphosphate and structural analogues on glucagon secretion from the perfused pancreas of rat in vitro.
Topics: 2-Chloroadenosine; 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Glucagon; In Vitro Techniques; Male; Nucleotidases; Pancreas; Rats; Theophylline | 1984 |
Adenosine receptors mediating cyclic AMP production in the rat hippocampus.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adrenergic Agonists; Animals; Cyclic AMP; Guanosine Monophosphate; Hippocampus; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic | 1982 |
Release of adenosine, inosine and hypoxanthine from rabbit non-myelinated nerve fibres at rest and during activity.
Topics: Action Potentials; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antimetabolites; Cyanides; Deoxyglucose; Glucose; Hydrolysis; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Nerve Fibers; Rabbits | 1984 |
Adenosine as a mediator of postcontraction hyperemia in dog gracilis muscle.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Animals; Dipyridamole; Dogs; Electric Conductivity; Female; Male; Muscle Contraction; Muscles; Oxygen Consumption; Perfusion | 1984 |
Does interstitial adenosine mediate acute hibernation of guinea pig myocardium?
Topics: 5'-Nucleotidase; Acute Disease; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cytosol; Guinea Pigs; Heart; Inosine; Lactates; Lactic Acid; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Stunning; Myocardium; Phosphorylation; Theophylline | 1995 |
P2-purinoceptor-mediated inhibition of noradrenaline release in rat atria.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antihypertensive Agents; Atropine; Desipramine; Dose-Response Relationship, Drug; Electric Stimulation; Heart Atria; Indomethacin; Male; Norepinephrine; Phenethylamines; Protein Synthesis Inhibitors; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Suramin; Triazines; Xanthines; Yohimbine | 1995 |
Alpha 1-adrenoceptor activation increases ecto-5'-nucleotidase activity and adenosine release in rat cardiomyocytes by activating protein kinase C.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; In Vitro Techniques; Indoles; Male; Maleimides; Methoxamine; Myocardium; Norepinephrine; Protein Kinase C; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Tetradecanoylphorbol Acetate | 1995 |
Contribution of endothelium and cardiomyocytes to hypoxia-induced adenosine release.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Cell Hypoxia; Coronary Circulation; Coronary Vessels; Endothelium, Vascular; Energy Metabolism; Heart; Male; Muscle Proteins; Myocardium; Perfusion; Rats; Rats, Sprague-Dawley; Uric Acid; Vasodilation | 1994 |
Infarct size-limiting effect of ischemic preconditioning is blunted by inhibition of 5'-nucleotidase activity and attenuation of adenosine release.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Dogs; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Time Factors | 1994 |
Intracellular formation and release of adenosine from rat hippocampal slices evoked by electrical stimulation or energy depletion.
Topics: Adenosine; Adenosine Diphosphate; Animals; Electric Stimulation; Energy Metabolism; Hippocampus; Homocysteine; In Vitro Techniques; Intracellular Membranes; Male; Purines; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine | 1993 |
Manipulation of endogenous adenosine in the rat prepiriform cortex modulates seizure susceptibility.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Kinase; Animals; Bicuculline; Cerebral Cortex; Male; Pentostatin; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Seizures; Theophylline; Thioinosine | 1993 |
Release of oxygen metabolites from chemoattractant-stimulated neutrophils is inhibited by resting platelets: role of extracellular adenosine and actin polymerization.
Topics: Actin Cytoskeleton; Actins; Adenine; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Biological Factors; Blood Platelets; Cells, Cultured; Chemotactic Factors; Chemotaxis, Leukocyte; Culture Media, Conditioned; Cytochalasin B; Humans; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Purinergic P1 Receptor Antagonists; Reactive Oxygen Species; Receptors, Purinergic P1; Respiratory Burst; Theophylline | 1996 |
Regulation of proliferation of LLC-MK2 cells by nucleosides and nucleotides: the role of ecto-enzymes.
Topics: 5'-Nucleotidase; Acid Anhydride Hydrolases; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Alkaline Phosphatase; Animals; Cell Division; Cell Line; Cell Line, Transformed; Dinucleoside Phosphates; Dipyridamole; Enzyme Inhibitors; HeLa Cells; Humans; Levamisole; Nucleoside-Triphosphatase; Nucleosides; Nucleotides; Suramin; Thymidine; Triazines | 1996 |
Preferential release of ATP and its extracellular catabolism as a source of adenosine upon high- but not low-frequency stimulation of rat hippocampal slices.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Electric Stimulation; Energy Metabolism; Enzyme Inhibitors; Hippocampus; In Vitro Techniques; Kinetics; Long-Term Potentiation; Male; Models, Neurological; Neurons; Rats; Rats, Wistar; Time Factors; Tritium | 1996 |
Studies on the roles of ATP, adenosine and nitric oxide in mediating muscle vasodilatation induced in the rat by acute systemic hypoxia.
Topics: 5'-Nucleotidase; Acute Disease; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Enzyme Inhibitors; Hypoxia; Male; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxygen Consumption; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Regional Blood Flow; Theophylline; Vasodilation | 1996 |
Activation of ecto-5'-nucleotidase by protein kinase C attenuates irreversible cellular injury due to hypoxia and reoxygenation in rat cardiomyocytes.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Cell Hypoxia; Cell Survival; Enzyme Activation; In Vitro Techniques; Male; Methoxamine; Myocardium; Oxygen; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 1996 |
Evidence for the involvement of ecto-5'-nucleotidase (CD73) in drug resistance.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Doxorubicin; Drug Resistance, Multiple; Humans; Mice; Rhodamines; RNA, Messenger; Tumor Cells, Cultured | 1996 |
A source of adenosine involved in cardiovascular responses to defense area stimulation.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Cardiovascular System; Defense Mechanisms; Electric Stimulation; Enzyme Inhibitors; Femoral Artery; Heart Rate; Male; Medulla Oblongata; Microinjections; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Solitary Nucleus | 1997 |
Vesnarinone limits infarct size via adenosine-dependent mechanisms in the canine heart.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Cardiotonic Agents; Dipyridamole; Dogs; Enzyme Activation; Enzyme Inhibitors; Infusions, Intra-Arterial; Ion Channel Gating; Myocardial Infarction; Myocardial Reperfusion Injury; Potassium Channels; Pyrazines; Quinolines; Receptors, Purinergic P1; Theophylline | 1997 |
P2-receptor-mediated inhibition of noradrenaline release in the rat hippocampus.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Electric Stimulation; Hippocampus; In Vitro Techniques; Isotope Labeling; Male; Norepinephrine; Phenethylamines; Rats; Rats, Wistar; Receptors, Purinergic P2; Thionucleotides; Triazines; Tritium; Xanthines; Yohimbine | 1997 |
Evidence against a major role of adenosine in oxygen-dependent regulation of erythropoietin in rats.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Animals; Antihypertensive Agents; Carbon Monoxide; Dipyridamole; Diuretics; Drug Synergism; Enzyme Inhibitors; Erythropoietin; Gene Expression; Hypoxia; Kidney; Male; Oxygen; Phenethylamines; Phosphodiesterase Inhibitors; Piperazines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; RNA, Messenger; Theophylline; Vasodilator Agents; Xanthines | 1997 |
Adenosine triphosphate degradation products after oxidative stress and metabolic dysfunction in cultured retinal cells.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Cell Hypoxia; Cells, Cultured; Chick Embryo; Enzyme Inhibitors; Glucose; Hypoxanthine; Inosine; Iodoacetates; Iodoacetic Acid; Ischemia; Kinetics; Oligomycins; Oxidative Stress; Retina; Thioinosine | 1997 |
Stimulation of alpha 1-adrenoceptors and protein kinase C-mediated activation of ecto-5'-nucleotidase in rat hearts in vivo.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Alkaloids; Analysis of Variance; Animals; Benzophenanthridines; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Female; Heart; Kinetics; Male; Methoxamine; Microdialysis; Myocardium; Norepinephrine; Perfusion; Phenanthridines; Prazosin; Protein Kinase C; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1 | 1997 |
Structure-based analysis of catalysis and substrate definition in the HIT protein family.
Topics: Acid Anhydride Hydrolases; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Binding Sites; Catalysis; Crystallography, X-Ray; Dimerization; Dinucleoside Phosphates; Hydrogen Bonding; Neoplasm Proteins; Nerve Tissue Proteins; Protein Structure, Secondary; Proteins; Structure-Activity Relationship; Substrate Specificity; Tungsten Compounds | 1997 |
The role of cyclic AMP as a precursor of extracellular adenosine in the rat hippocampus.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Animals; Colforsin; Cyclic AMP; Diterpenes; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Guanosine Monophosphate; Hippocampus; In Vitro Techniques; Male; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theophylline | 1997 |
Effects of ischemic preconditioning on contractile and metabolic function during hypoperfusion in dogs.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Blood Flow Velocity; Coronary Circulation; Coronary Vessels; Dogs; Enzyme Inhibitors; Hydrogen-Ion Concentration; Ischemic Preconditioning, Myocardial; Lactic Acid; Myocardial Contraction; Myocardium; Purinergic P1 Receptor Antagonists; Theophylline | 1998 |
P2 purinoceptors contribute to ATP-induced inhibition of L-type Ca2+ current in rabbit atrial myocytes.
Topics: 1-Methyl-3-isobutylxanthine; 5'-Nucleotidase; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Calcium-Transporting ATPases; Colforsin; Cyclic AMP; Enzyme Inhibitors; Isoproterenol; Myocardium; Patch-Clamp Techniques; Pertussis Toxin; Potassium Channels; Potassium Channels, Voltage-Gated; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rabbits; Receptors, Purinergic P2; Shal Potassium Channels; Suramin; Virulence Factors, Bordetella; Xanthines | 1999 |
Immunologically distinct isoforms of ecto-5'-nucleotidase in nerve terminals of different areas of the rat hippocampus.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Extracellular Space; Hippocampus; Immune Sera; Immunologic Techniques; Isoenzymes; Kinetics; Nerve Endings; Rabbits; Rats; Synaptosomes; Tissue Distribution | 2000 |
Reserpine attenuates interstitial adenosine-mediated activation of ecto-5'-nucleotidase in rat hearts in vivo.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adrenergic Uptake Inhibitors; Animals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Activation; Heart; Male; Microdialysis; Myocardium; Norepinephrine; Perfusion; Phosphorylation; Rats; Rats, Wistar; Reserpine; Stellate Ganglion; Tyramine | 2000 |
Complex hippocampal responses to ATP: fade due to nucleotidase inhibition and P2-receptor-mediated adenosine release.
Topics: 5'-Nucleotidase; Action Potentials; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Enzyme Inhibitors; Hippocampus; Male; Nerve Tissue Proteins; Rats; Rats, Wistar; Receptors, Purinergic P2; Suramin; Theophylline | 2000 |
Role of A(2A)-adenosine receptor activation for ATP-mediated coronary vasodilation in guinea-pig isolated heart.
Topics: Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Coronary Vessels; Glyburide; Guinea Pigs; NG-Nitroarginine Methyl Ester; Perfusion; Receptors, Purinergic P1; Thionucleotides; Vasodilation | 2000 |
Extracellular ATP reduces optically monitored electrical signals in hippocampal slices through metabolism to adenosine.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Electrophysiology; Hippocampus; Organ Culture Techniques; Rats; Rats, Wistar; Signal Transduction; Triazines; Triazoles; Uridine Diphosphate; Xanthines | 2000 |
Correlation between adenine nucleotide-induced cyclic AMP elevation and extracellular adenosine formation in NG108-15 cells.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cell Membrane; Chromatography, High Pressure Liquid; Cyclic AMP; Enzyme Inhibitors; Extracellular Space; Nucleotidases; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured | 2000 |
Simultaneous assessment of ecto- and cytosolic-5'-nucleotidase activities in brain micropunches.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Brain; Cell Membrane; Chromatography, High Pressure Liquid; Cytosol; Enzyme Inhibitors; Magnesium; Male; Nucleotidases; Rats; Rats, Sprague-Dawley | 2000 |
Adenosine linking reduced O2 to arteriolar NO release in intestine is not formed from extracellular ATP.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Arterioles; Enzyme Inhibitors; Extracellular Space; Intestine, Small; Male; Nitric Oxide; omega-N-Methylarginine; Oxygen; Rats; Rats, Sprague-Dawley; Vascular Patency; Vasoconstriction; Xanthines | 2001 |
Oxidative stress enhances the production and actions of adenosine in the kidney.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Catalase; Chromatography, High Pressure Liquid; Cyclic N-Oxides; Dimerization; Ditiocarb; Kidney; Kinetics; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Renal Artery; Spin Labels; Superoxide Dismutase; Superoxides; Thioredoxins; Xanthine; Xanthine Oxidase | 2001 |
Nucleotide-evoked relaxation of rat vas deferens: possible mechanisms.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cyclic AMP; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscle Relaxation; Nucleotides; Potassium; Rats; Rats, Wistar; Theophylline; Thionucleotides; Vas Deferens | 2002 |
Complementary role of extracellular ATP and adenosine in ischemic preconditioning in the rat heart.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Coloring Agents; Extracellular Space; Ischemic Preconditioning; Male; Microdialysis; Organic Chemicals; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Receptors, Purinergic P2; Suramin; Theophylline; Ventricular Function, Left; Ventricular Pressure | 2002 |
Magnesium reduces myocardial infarct size via enhancement of adenosine mechanism in rabbits.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Analysis of Variance; Animals; Calcium; Drug Synergism; Enzyme Inhibitors; Magnesium; Male; Models, Animal; Myocardial Infarction; Myocardium; Purinergic P1 Receptor Antagonists; Rabbits; Theophylline | 2002 |
Enzyme kinetics and pharmacological characterization of nucleotidases released from the guinea pig isolated vas deferens during nerve stimulation: evidence for a soluble ecto-nucleoside triphosphate diphosphohydrolase-like ATPase and a soluble ecto-5'-nuc
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Calcium; Chromatography, High Pressure Liquid; Electric Stimulation; Enzyme Inhibitors; Guinea Pigs; In Vitro Techniques; Kinetics; Magnesium; Male; Nucleotidases; Phosphoric Diester Hydrolases; Phosphoric Monoester Hydrolases; Plant Proteins; Pyrophosphatases; Suramin; Sympathetic Nervous System; Vas Deferens | 2002 |
Rapid adenosine release in the nucleus tractus solitarii during defence response in rats: real-time measurement in vivo.
Topics: Adenosine; Adenosine Diphosphate; Animals; Biosensing Techniques; Brain Stem; Computer Systems; Electric Stimulation; Enzyme Inhibitors; Escape Reaction; Hypothalamus; Inosine; Microelectrodes; Rats; Rats, Sprague-Dawley; Solitary Nucleus; Time Factors | 2002 |
Extracellular purines from cells of seminiferous tubules.
Topics: 5'-Nucleotidase; Adenine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Animals; Cells, Cultured; Dipyridamole; Enzyme Inhibitors; Extracellular Space; Germ Cells; Kinetics; Male; Paracrine Communication; Phosphodiesterase Inhibitors; Purines; Rats; Rats, Wistar; Receptors, Purinergic; Seminiferous Tubules; Sertoli Cells; Thioinosine | 2003 |
Cilostazol, an inhibitor of type 3 phosphodiesterase, stimulates large-conductance, calcium-activated potassium channels in pituitary GH3 cells and pheochromocytoma PC12 cells.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Action Potentials; Adenoma; Adenosine; Adenosine Diphosphate; Animals; Calcium Channels, L-Type; Cilostazol; Cyclic Nucleotide Phosphodiesterases, Type 3; Electric Conductivity; Enzyme Inhibitors; Kinetics; Large-Conductance Calcium-Activated Potassium Channels; PC12 Cells; Phosphodiesterase Inhibitors; Pituitary Gland, Anterior; Pituitary Neoplasms; Potassium Channels, Calcium-Activated; Rats; Tetrazoles | 2004 |
Hypoxia induces adenosine release from the rat carotid body.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Carotid Body; Carrier Proteins; Chemoreceptor Cells; Dipyridamole; Enzyme Inhibitors; Hypoxia; In Vitro Techniques; Membrane Transport Proteins; Nucleoside Transport Proteins; Rats; Rats, Wistar; Thioinosine | 2004 |
Regulation of VEGF and bFGF mRNA expression and other proliferative compounds in skeletal muscle cells.
Topics: Adenosine; Adenosine Diphosphate; Animals; Cell Proliferation; Cells, Cultured; Electric Stimulation; Endothelium, Vascular; Fibroblast Growth Factor 2; Gene Expression Regulation; Humans; Indomethacin; Male; Muscle Cells; Muscle Contraction; Muscle, Skeletal; Nitric Oxide; Nitroarginine; Penicillamine; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; RNA, Messenger; Vascular Endothelial Growth Factor A | 2004 |
Amitriptyline enhances extracellular tissue levels of adenosine in the rat hindpaw and inhibits adenosine uptake.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Biological Transport; Capsaicin; Cell Line, Tumor; Dose-Response Relationship, Drug; Equilibrative-Nucleoside Transporter 2; Extracellular Space; Hindlimb; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Time Factors | 2005 |
Ecto-5'-nucleotidase promotes invasion, migration and adhesion of human breast cancer cells.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Breast Neoplasms; Cell Adhesion; Cell Movement; Extracellular Matrix; Female; Humans; Neoplasm Invasiveness; Transfection | 2008 |
Lack of effect of extracellular adenosine generation and signaling on renal erythropoietin secretion during hypoxia.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Arteries; Carbon Monoxide; Erythropoietin; Extracellular Fluid; Hemodilution; Hypoxia; Kidney; Mice; Mice, Inbred C57BL; Mice, Knockout; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; RNA, Messenger; Signal Transduction | 2007 |
Role of extracellular nucleotide phosphohydrolysis in intestinal ischemia-reperfusion injury.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Base Sequence; Caco-2 Cells; Cell Line; DNA Primers; Enzyme Inhibitors; Extracellular Fluid; Female; Humans; Hydrolysis; Interleukin-1beta; Interleukin-6; Intestinal Mucosa; Intestines; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Purinergic P1; Reperfusion Injury; Signal Transduction | 2008 |
Ischemia-driven expression of CD73 confers tissue protection during liver ischemia/reperfusion.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Disease Models, Animal; Extracellular Fluid; Liver; Mice; Mice, Knockout; Reperfusion Injury | 2008 |
Studies of the extracellular ATP-adenosine pathway in human urinary tract epithelial cells.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Biosynthetic Pathways; Cell Line; Epithelial Cells; Humans; Neutrophils; Nucleotidases; Urinary Tract | 2009 |
Adenosine A1 receptors and microglial cells mediate CX3CL1-induced protection of hippocampal neurons against Glu-induced death.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine Deaminase; Adenosine Diphosphate; Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Cell Death; Cell Movement; Clodronic Acid; CX3C Chemokine Receptor 1; Erythropoietin; Glutamic Acid; Green Fluorescent Proteins; Hippocampus; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Neurons; Organ Culture Techniques; Rats; Receptor, Adenosine A1; Receptors, Adenosine A2; Receptors, Chemokine; Xanthines | 2010 |
CD73 has distinct roles in nonhematopoietic and hematopoietic cells to promote tumor growth in mice.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Chemotaxis, Leukocyte; Disease Progression; Female; Immunotherapy, Adoptive; Lymphocytes, Tumor-Infiltrating; Lymphoma, Non-Hodgkin; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Molecular Targeted Therapy; Ovarian Neoplasms; Peritoneal Neoplasms; Radiation Chimera; Second Messenger Systems; T-Lymphocytes; T-Lymphocytes, Regulatory; Tumor Burden | 2011 |
Role of the ecto-nucleotidases in the cooperative effect of adenosine and neuropeptide-S on locomotor activity in mice.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Enzyme Inhibitors; Injections, Intraventricular; Male; Mice; Motor Activity; Neostriatum; Neuropeptides | 2011 |
Alterations in the extracellular catabolism of nucleotides are involved in the antiproliferative effect of quercetin in human bladder cancer T24 cells.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Synergism; Extracellular Space; GPI-Linked Proteins; Humans; Hydrolysis; Nucleotides; Quercetin; Time Factors; Urinary Bladder Neoplasms | 2013 |
Neuronal adenosine release, and not astrocytic ATP release, mediates feedback inhibition of excitatory activity.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Astrocytes; Brain; CA1 Region, Hippocampal; Excitatory Postsynaptic Potentials; Feedback, Physiological; GPI-Linked Proteins; Long-Term Synaptic Depression; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Patch-Clamp Techniques; Receptor, Adenosine A1; Seizures | 2012 |
Extracellular 2',3'-cAMP-adenosine pathway in proximal tubular, thick ascending limb, and collecting duct epithelial cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Epithelial Cells; Kidney Tubules, Collecting; Kidney Tubules, Proximal; Loop of Henle; Male; Rats; Rats, Sprague-Dawley; Xanthines | 2013 |
Crystal structure of the human ecto-5'-nucleotidase (CD73): insights into the regulation of purinergic signaling.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Amino Acid Sequence; Catalytic Domain; Coordination Complexes; Crystallography, X-Ray; Enzyme Inhibitors; Flavonoids; GPI-Linked Proteins; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Molecular Sequence Data; Protein Binding; Protein Interaction Domains and Motifs; Protein Structure, Quaternary; Protein Structure, Secondary; Protein Subunits; Signal Transduction; Structural Homology, Protein; Zinc | 2012 |
The volatile anesthetic isoflurane increases endothelial adenosine generation via microparticle ecto-5'-nucleotidase (CD73) release.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Amides; Anesthetics, Inhalation; Animals; Antigens, CD; Cadherins; Cell Line, Transformed; Cell-Derived Microparticles; Endothelial Cells; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Isoflurane; Kidney Glomerulus; Male; Mice; Mice, Inbred C57BL; Myosin-Light-Chain Phosphatase; Pyridines; rho-Associated Kinases; Signal Transduction | 2014 |
Role of adenosine signaling on pentylenetetrazole-induced seizures in zebrafish.
Topics: Adenine; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine Diphosphate; Animals; Benzyl Compounds; Convulsants; Dipyridamole; Gene Expression Regulation; Genes, fos; Pentylenetetrazole; Phenethylamines; Phosphodiesterase Inhibitors; Seizures; Signal Transduction; Thioinosine; Xanthines; Zebrafish | 2015 |
Different danger signals differently impact on microglial proliferation through alterations of ATP release and extracellular metabolism.
Topics: 5'-Nucleotidase; Adenosine; Adenosine A2 Receptor Antagonists; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Apyrase; Cell Line; Cell Proliferation; Cells, Cultured; Enzyme Inhibitors; Extracellular Space; Glutamic Acid; Lipopolysaccharides; Mice, Inbred C57BL; Microglia; Pyrimidines; Receptors, Adenosine A2; Triazoles | 2015 |
CD73 Activity is Dispensable for the Polarization of M2 Macrophages.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Cytokines; Flow Cytometry; GPI-Linked Proteins; Humans; Immunosuppressive Agents; Inflammation; Interferon-gamma; Interleukin-4; Lipopolysaccharides; Macrophage Colony-Stimulating Factor; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Monocytes; Phenotype | 2015 |
Extracellular adenosine produced by ecto-5'-nucleotidase (CD73) regulates macrophage pro-inflammatory responses, nitric oxide production, and favors Salmonella persistence.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Cytokines; Host-Pathogen Interactions; Inflammation; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type II; RAW 264.7 Cells; Salmonella Infections; Salmonella typhimurium | 2018 |
Adenosine Production by Biomaterial-Supported Mesenchymal Stromal Cells Reduces the Innate Inflammatory Response in Myocardial Ischemia/Reperfusion Injury.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Cells, Cultured; Coculture Techniques; Disease Models, Animal; Enzyme Inhibitors; GPI-Linked Proteins; Humans; Hydrogen Peroxide; Immunity, Innate; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Neutrophils; Rats, Sprague-Dawley; Recovery of Function; Stem Cell Niche; Tissue Scaffolds | 2018 |
Enhanced ATP release and CD73-mediated adenosine formation sustain adenosine A
Topics: 5'-Nucleotidase; Adenosine; Adenosine A2 Receptor Antagonists; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cell Line, Tumor; Humans; Male; Oxidopamine; Parkinsonian Disorders; Pyrimidines; Rats, Wistar; Receptor, Adenosine A2A; Triazoles | 2019 |
e5NT inhibitor protects acute restraint stress-induced depression by regulating nucleoside release in mice.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Elevated Plus Maze Test; Enzyme Inhibitors; Exploratory Behavior; GPI-Linked Proteins; Hippocampus; Male; Mice; Open Field Test; Restraint, Physical; Stress, Psychological; Uridine | 2020 |
Inhibition of ecto-5'-nucleotidase and adenosine deaminase is able to reverse long-term behavioural effects of early ethanol exposure in zebrafish (Danio rerio).
Topics: 5'-Nucleotidase; Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Animals; Antisocial Personality Disorder; Behavior, Animal; Disease Models, Animal; Ethanol; Female; Humans; Pregnancy; Prenatal Exposure Delayed Effects; Social Interaction; Zebrafish | 2020 |