Page last updated: 2024-09-05

adenosine 2',5'-diphosphate and adenosine diphosphate

adenosine 2',5'-diphosphate has been researched along with adenosine diphosphate in 32 studies

Compound Research Comparison

Studies
(adenosine 2',5'-diphosphate)
Trials
(adenosine 2',5'-diphosphate)
Recent Studies (post-2010)
(adenosine 2',5'-diphosphate)
Studies
(adenosine diphosphate)
Trials
(adenosine diphosphate)
Recent Studies (post-2010) (adenosine diphosphate)
290223,9894983,114
70023,9894983,114

Protein Interaction Comparison

ProteinTaxonomyadenosine 2',5'-diphosphate (IC50)adenosine diphosphate (IC50)
Chain A, Kinesin-like protein KIF11Homo sapiens (human)0.45
Heat shock 70 kDa protein 1A Homo sapiens (human)0.5
Sensor protein kinase WalKStaphylococcus aureus7.189

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19905 (15.63)18.7374
1990's9 (28.13)18.2507
2000's16 (50.00)29.6817
2010's2 (6.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Callahan, L; Ng, K; Schwartz, N1
Daniels, MJ; Herriott, JR; Karplus, PA1
Fujii, S; Miura, R; Nonaka, Y; Okamoto, M1
Günther Sillero, MA; Meireles Ribeiro, J; Ruiz, A; Sillero, A1
Hilz, H1
Buitrago, F; Canales, J; Sillero, A; Sillero, MA1
Fernandez, VM; Llobell, A; López-Barea, J1
Colman, RF; Mas, MT1
Buitrago, F; Canales, J; Günther-Sillero, MA; Sillero, A1
Chang, GG; Chou, WY; Huang, SM; Liu, YH1
Clark, MG; Colquhoun, EQ; Dora, KA; Rattigan, S; Richards, SM1
Kirk, A; Nicholls, DJ; Wallace, AV1
MacKenzie, RE; Pawelek, PD1
Boeynaems, JM; Communi, D; Robaye, B1
Dangelmaier, C; Daniel, JL; Jin, J; Kunapuli, SP; Smith, JB1
Lin, ES; Yang, YS1
Enkvist, E; Järv, J; Kelve, M; Raidaru, G; Sak, K; Subbi, J; Uri, A1
Jones, JP; Rock, D1
Hoylaerts, MF; Oury, C; Toth-Zsamboki, E; Tytgat, J; Vermylen, J1
Acharya, KR; Boix, E; Cuchillo, CM; Evans, HR; Mohan, CG; Nikolovski, Z; Nogués, MV1
Heptinstall, S; May, JA; Storey, RF1
Grunau, A; Gutierrez, A; Ladbury, JE; Paine, MJ1
Aliverti, A; Balconi, E; Bolognesi, M; Mastrangelo, E; Milani, M; Seeber, F; Zanetti, G1
Geraki, K; Grossmann, JG; Grunau, A; Gutierrez, A1
Bortolotti, A; Carrillo, N; Cortez, N; Goñi, G; Hermoso, JA; Medina, M; Pérez-Dorado, I1
Barsukov, IL; Ellis, J; Grossmann, JG; Gutierrez, A; Huang, WC; Roberts, GCK1
Lian, LY; McLaughlin, LA; Paine, MJ; Widdowson, P1
Castillo, R; Childers, MC; Daggett, V; Flint, GV; Irving, TC; Ma, W; McCabe, KJ; McCulloch, AD; Mohran, S; Moussavi-Harami, F; Murray, JD; Powers, JD; Regnier, M; Yuan, CC; Zuzek, C1
Acharya, KR; Boix, E; Leonidas, DD; Minson, K; Prill, R; Suzuki, M; Swaminathan, GJ; Turton, R; Youle, RJ1
Acharya, KR; Chavali, GB; Chrysina, ED; Frankling, C; Kosmopoulou, MN; Leonidas, DD; Oikonomakos, NG; Vlassi, M1
Abell, C; Blundell, TL; Ciulli, A; Smith, AG; Williams, G1

Reviews

1 review(s) available for adenosine 2',5'-diphosphate and adenosine diphosphate

ArticleYear
Phospho adenylylation and phospho ADP-ribosylation, types of covalent protein modification derived from NADP.
    BioFactors (Oxford, England), 1988, Volume: 1, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Diphosphate Ribose; Animals; GTP-Binding Proteins; NADP; Proteins

1988

Other Studies

31 other study(ies) available for adenosine 2',5'-diphosphate and adenosine diphosphate

ArticleYear
Dibasic amines as competitive ions improve the resolution between polyanionic nucleotides.
    Analytical biochemistry, 1991, Aug-01, Volume: 196, Issue:2

    Topics: Adenine Nucleotides; Adenosine Diphosphate; Binding, Competitive; Chromatography, Ion Exchange; Diamines; Phosphoadenosine Phosphosulfate

1991
Atomic structure of ferredoxin-NADP+ reductase: prototype for a structurally novel flavoenzyme family.
    Science (New York, N.Y.), 1991, Jan-04, Volume: 251, Issue:4989

    Topics: Adenosine Diphosphate; Amino Acid Sequence; Binding Sites; Crystallization; Ferredoxin-NADP Reductase; Ferredoxins; Flavin-Adenine Dinucleotide; Hydrogen Bonding; Molecular Sequence Data; Molecular Structure; NADP; Nucleotides; Plants; Protein Conformation; Sequence Homology, Nucleic Acid; X-Ray Diffraction

1991
On the ligand-protein and ligand-flavin interactions in NADPH-adrenodoxin reductase as studied by 31P- and 13C-NMR. Use of 13C-enriched FAD as a probe.
    Journal of biochemistry, 1991, Volume: 109, Issue:1

    Topics: Adenosine Diphosphate; Adrenal Cortex; Animals; Binding Sites; Cattle; Ferredoxin-NADP Reductase; Flavin-Adenine Dinucleotide; In Vitro Techniques; Magnetic Resonance Spectroscopy; Molecular Probes

1991
A low Km nucleoside 3'(2'),5-bisphosphate 3'(2')-phosphohydrolase from rat liver.
    Biochimie, 1990, Volume: 72, Issue:4

    Topics: Adenosine Diphosphate; Animals; Female; Hydrolysis; Isoenzymes; Kinetics; Liver; Nucleoside-Triphosphatase; Nucleotidases; Nucleotides; Phosphoric Monoester Hydrolases; Rats; Rats, Inbred Strains; Substrate Specificity

1990
Rat liver contains a novel nucleotide, Ypp5'A2'p, related to adenosine 2',5'-bisphosphate.
    Biochemistry international, 1987, Volume: 15, Issue:2

    Topics: Adenine Nucleotides; Adenosine Diphosphate; Animals; Chromatography, High Pressure Liquid; Liver; Male; Oligonucleotides; Rats; Spectrophotometry, Ultraviolet; Structure-Activity Relationship

1987
Electron transfer between reduced methyl viologen and oxidized glutathione: a new assay of Saccharomyces cerevisiae glutathione reductase.
    Archives of biochemistry and biophysics, 1986, Nov-01, Volume: 250, Issue:2

    Topics: Adenosine Diphosphate; Adenosine Diphosphate Ribose; Electrochemistry; Electron Transport; Enzyme Activation; Glutathione; Glutathione Disulfide; Glutathione Reductase; Oxidation-Reduction; Paraquat; Saccharomyces cerevisiae; Spectrophotometry

1986
Spectroscopic studies of the interactions of coenzymes and coenzyme fragments with pig heart, oxidized triphosphopyridine nucleotide specific isocitrate dehydrogenase.
    Biochemistry, 1985, Mar-26, Volume: 24, Issue:7

    Topics: Adenosine Diphosphate; Adenosine Diphosphate Ribose; Animals; Binding Sites; Coenzymes; In Vitro Techniques; Isocitrate Dehydrogenase; Kinetics; Myocardium; NADP; Protein Conformation; Spectrum Analysis; Sulfates; Swine

1985
Occurrence of adenosine 2',5'-bisphosphate in rat liver.
    Biochimica et biophysica acta, 1986, Apr-11, Volume: 881, Issue:2

    Topics: Adenosine Diphosphate; Alkaline Phosphatase; Animals; Chromatography, DEAE-Cellulose; Chromatography, High Pressure Liquid; Liver; Male; Rats

1986
Cloning and expression of pigeon liver cytosolic NADP(+)-dependent malic enzyme cDNA and some of its abortive mutants.
    Archives of biochemistry and biophysics, 1994, Volume: 310, Issue:1

    Topics: Adenosine Diphosphate; Amino Acid Sequence; Animals; Base Sequence; Chromatography, Affinity; Cloning, Molecular; Columbidae; Cytosol; DNA Probes; DNA, Complementary; Escherichia coli; Gene Library; Liver; Malate Dehydrogenase; Molecular Sequence Data; Mutation; NADP; Protein Conformation; Recombinant Proteins; Sequence Analysis, DNA; Sequence Homology, Amino Acid

1994
Role of extracellular UTP in the release of uracil from vasoconstricted hindlimb.
    The American journal of physiology, 1993, Volume: 264, Issue:1 Pt 2

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Aorta; Blood Pressure; Extracellular Space; Hindlimb; Male; Muscle, Smooth, Vascular; Nucleotides; Oxygen Consumption; Rats; Rats, Wistar; Uracil; Uridine Monophosphate; Uridine Triphosphate; Vasoconstriction

1993
Reversibility of inhibition of human type II nitric oxide synthase.
    Biochemical Society transactions, 1996, Volume: 24, Issue:1

    Topics: Adenosine Diphosphate; Animals; Arginine; Cell Line; Colonic Neoplasms; Enzyme Inhibitors; Humans; Isoenzymes; Isothiuronium; Kinetics; Macrophages; Mice; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Onium Compounds; Tumor Cells, Cultured

1996
Methenyltetrahydrofolate cyclohydrolase is rate limiting for the enzymatic conversion of 10-formyltetrahydrofolate to 5,10-methylenetetrahydrofolate in bifunctional dehydrogenase-cyclohydrolase enzymes.
    Biochemistry, 1998, Jan-27, Volume: 37, Issue:4

    Topics: Adenosine Diphosphate; Aminohydrolases; Bacterial Proteins; Formate-Tetrahydrofolate Ligase; Humans; Kinetics; Leucovorin; Methylenetetrahydrofolate Dehydrogenase (NADP); Mitochondria; Models, Chemical; Multienzyme Complexes; NAD; NADP; Photobacterium; Tetrahydrofolates

1998
Pharmacological characterization of the human P2Y11 receptor.
    British journal of pharmacology, 1999, Volume: 128, Issue:6

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; CHO Cells; Cricetinae; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Inositol 1,4,5-Trisphosphate; Phosphoadenosine Phosphosulfate; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Recombinant Fusion Proteins; Suramin; Theophylline; Thionucleotides; Time Factors; Triazines; Tumor Cells, Cultured

1999
The P2Y1 receptor mediates ADP-induced p38 kinase-activating factor generation in human platelets.
    European journal of biochemistry, 2000, Volume: 267, Issue:8

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Aspirin; Blood Platelets; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Platelet Activation; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2Y1; Signal Transduction; Thromboxane A2; Vasoconstrictor Agents

2000
Nucleotide binding and sulfation catalyzed by phenol sulfotransferase.
    Biochemical and biophysical research communications, 2000, May-19, Volume: 271, Issue:3

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Arylsulfotransferase; Chromatography, High Pressure Liquid; Cyclic AMP; Kinetics; Magnetic Resonance Spectroscopy; Nitrobenzenes; Nucleotides; Protein Binding; Recombinant Proteins; Spectrophotometry; Substrate Specificity; Sulfates

2000
Adenosine-derived non-phosphate antagonists for P2Y(1) purinoceptors.
    Biochemical and biophysical research communications, 2000, Jun-07, Volume: 272, Issue:2

    Topics: Adenosine; Adenosine Diphosphate; Aspartic Acid; Astrocytoma; Dose-Response Relationship, Drug; Humans; Phosphates; Phosphatidylinositols; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Thionucleotides; Tumor Cells, Cultured

2000
Inexpensive purification of P450 reductase and other proteins using 2',5'-adenosine diphosphate agarose affinity columns.
    Protein expression and purification, 2001, Volume: 22, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Bacterial Proteins; Chromatography, Affinity; Chromatography, Agarose; Cytochrome P-450 Enzyme System; Mixed Function Oxygenases; NADPH-Ferrihemoprotein Reductase; Protein Binding

2001
The P2Y1 receptor antagonist adenosine-2',5'-diphosphate non-selectively antagonizes the platelet P2X1 ion channel.
    Thrombosis and haemostasis, 2001, Volume: 86, Issue:5

    Topics: Adenosine Diphosphate; Blood Platelets; Humans; Ion Channels; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2X; Receptors, Purinergic P2Y1; Substrate Specificity

2001
The crystal structure of eosinophil cationic protein in complex with 2',5'-ADP at 2.0 A resolution reveals the details of the ribonucleolytic active site.
    Biochemistry, 2002, Oct-08, Volume: 41, Issue:40

    Topics: Adenosine Diphosphate; Amino Acid Sequence; Binding Sites; Blood Proteins; Conserved Sequence; Crystallography, X-Ray; Eosinophil Granule Proteins; Hydrogen Bonding; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Tertiary; Ribonucleases; Sequence Alignment

2002
Potentiation of platelet aggregation by heparin in human whole blood is attenuated by P2Y12 and P2Y1 antagonists but not aspirin.
    Thrombosis research, 2005, Volume: 115, Issue:4

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Aspirin; Blood Platelets; Cell Degranulation; Dalteparin; Drug Synergism; Heparin; Hirudins; Humans; In Vitro Techniques; Membrane Proteins; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12

2005
Global effects of the energetics of coenzyme binding: NADPH controls the protein interaction properties of human cytochrome P450 reductase.
    Biochemistry, 2006, Feb-07, Volume: 45, Issue:5

    Topics: Adenosine Diphosphate; Calorimetry; Coenzymes; Cytochromes c; Humans; Kinetics; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Phosphates; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Temperature; Thermodynamics; Titrimetry

2006
Ferredoxin-NADP+ reductase from Plasmodium falciparum undergoes NADP+-dependent dimerization and inactivation: functional and crystallographic analysis.
    Journal of molecular biology, 2007, Mar-23, Volume: 367, Issue:2

    Topics: Adenosine Diphosphate; Amino Acid Sequence; Animals; Binding Sites; Crystallography, X-Ray; Dimerization; Enzyme Activation; Ferredoxin-NADP Reductase; Models, Molecular; Molecular Sequence Data; NADP; Plasmodium falciparum; Protein Conformation; Recombinant Proteins

2007
Conformational dynamics and the energetics of protein--ligand interactions: role of interdomain loop in human cytochrome P450 reductase.
    Biochemistry, 2007, Jul-17, Volume: 46, Issue:28

    Topics: Adenosine Diphosphate; Calorimetry; Humans; Kinetics; Ligands; Models, Molecular; Mutagenesis; NADPH-Ferrihemoprotein Reductase; Protein Binding; Protein Structure, Tertiary; Scattering, Small Angle; Thermodynamics; X-Ray Diffraction

2007
Coenzyme binding and hydride transfer in Rhodobacter capsulatus ferredoxin/flavodoxin NADP(H) oxidoreductase.
    Biochimica et biophysica acta, 2009, Volume: 1794, Issue:2

    Topics: Adenosine; Adenosine Diphosphate; Bacterial Proteins; Catalytic Domain; Crystallography, X-Ray; Ferredoxin-NADP Reductase; Ferredoxins; Flavodoxin; Kinetics; Models, Molecular; NADP; Protein Binding; Protein Conformation; Recombinant Proteins; Rhodobacter capsulatus

2009
Domain motion in cytochrome P450 reductase: conformational equilibria revealed by NMR and small-angle x-ray scattering.
    The Journal of biological chemistry, 2009, Dec-25, Volume: 284, Issue:52

    Topics: Adenosine Diphosphate; Animals; Crystallography, X-Ray; Electron Transport; Horses; Humans; NADP; NADPH-Ferrihemoprotein Reductase; Nuclear Magnetic Resonance, Biomolecular; Protein Structure, Tertiary; Rats; Scattering, Radiation; X-Rays

2009
Two conformations are better than one: domain motion in cytochrome P450 reductase. conformational equilibria revealed by nmr and small-angle X-ray scattering.
    The Journal of biological chemistry, 2009, Dec-25, Volume: 284, Issue:52

    Topics: Adenosine Diphosphate; Animals; Crystallography, X-Ray; Electron Transport; Horses; Humans; NADP; NADPH-Ferrihemoprotein Reductase; Nuclear Magnetic Resonance, Biomolecular; Protein Structure, Tertiary; Rats; Scattering, Radiation; X-Rays

2009
Biochemical comparison of Anopheles gambiae and human NADPH P450 reductases reveals different 2'-5'-ADP and FMN binding traits.
    PloS one, 2011, Volume: 6, Issue:5

    Topics: Adenosine Diphosphate; Amino Acid Sequence; Animals; Anopheles; Binding Sites; Calorimetry; Cytochromes c; Flavin Mononucleotide; Humans; Insect Proteins; Molecular Sequence Data; NADP; NADPH-Ferrihemoprotein Reductase; Protein Binding; Sequence Homology, Amino Acid

2011
Cardiac myosin activation with 2-deoxy-ATP via increased electrostatic interactions with actin.
    Proceedings of the National Academy of Sciences of the United States of America, 2019, 06-04, Volume: 116, Issue:23

    Topics: Actin Cytoskeleton; Actins; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cardiac Myosins; Deoxyadenine Nucleotides; Kinetics; Male; Muscle Contraction; Myocardium; Protein Binding; Rats; Rats, Inbred F344; Sarcomeres; Static Electricity

2019
Mapping the ribonucleolytic active site of eosinophil-derived neurotoxin (EDN). High resolution crystal structures of EDN complexes with adenylic nucleotide inhibitors.
    The Journal of biological chemistry, 2001, May-04, Volume: 276, Issue:18

    Topics: Adenosine Diphosphate; Binding Sites; Crystallography, X-Ray; Eosinophil-Derived Neurotoxin; Models, Molecular; Protein Binding; Protein Conformation; Recombinant Proteins; Ribonuclease, Pancreatic; Ribonucleases

2001
High-resolution crystal structures of ribonuclease A complexed with adenylic and uridylic nucleotide inhibitors. Implications for structure-based design of ribonucleolytic inhibitors.
    Protein science : a publication of the Protein Society, 2003, Volume: 12, Issue:11

    Topics: Adenosine Diphosphate; Animals; Binding Sites; Blood Proteins; Cattle; Crystallography, X-Ray; Drug Design; Enzyme Inhibitors; Eosinophil Granule Proteins; Eosinophil-Derived Neurotoxin; Humans; Hydrogen Bonding; Models, Molecular; Protein Binding; Protein Conformation; Ribonuclease, Pancreatic; Ribonucleases; Uracil Nucleotides

2003
Probing hot spots at protein-ligand binding sites: a fragment-based approach using biophysical methods.
    Journal of medicinal chemistry, 2006, Aug-10, Volume: 49, Issue:16

    Topics: Alcohol Oxidoreductases; Amino Acid Sequence; Binding Sites; Biophysical Phenomena; Biophysics; Calorimetry; Escherichia coli; Ligands; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Nucleotides; Protein Binding; Structure-Activity Relationship; Thermodynamics

2006