Page last updated: 2024-09-03

adenophostin a and adenine

adenophostin a has been researched along with adenine in 6 studies

*Adenine: A purine base and a fundamental unit of ADENINE NUCLEOTIDES. [MeSH]

*Adenine: A purine base and a fundamental unit of ADENINE NUCLEOTIDES. [MeSH]

Compound Research Comparison

Studies
(adenophostin a)
Trials
(adenophostin a)
Recent Studies (post-2010)
(adenophostin a)
Studies
(adenine)
Trials
(adenine)
Recent Studies (post-2010) (adenine)
9201221,9031,1537,682

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's3 (50.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hosoya, T; Kagasaki, T; Takahashi, M; Takahashi, S1
Bultynck, G; Casteels, R; De Smedt, H; De Smet, P; Maes, K; Missiaen, L; Parys, JB; Sienaert, I; Zizi, M1
Correa, V; Jenkins, DJ; Marwood, RD; Potter, BV; Taylor, CW1
Dozol, H; Graff, R; Maechling, C; Matsuda, A; Shuto, S; Spiess, B1
Black, SJ; Borissow, CN; Dedos, SG; Paul, M; Potter, BV; Taylor, CW; Tovey, SC1
Potter, BV; Riley, AM; Sureshan, KM; Taylor, CW; Thomas, MP; Tovey, SC1

Other Studies

6 other study(ies) available for adenophostin a and adenine

ArticleYear
Adenophostins A and B: potent agonists of inositol-1,4,5-trisphosphate receptor produced by Penicillium brevicompactum. Taxonomy, fermentation, isolation, physico-chemical and biological properties.
    The Journal of antibiotics, 1993, Volume: 46, Issue:11

    Topics: Adenine; Adenosine; Animals; Calcium Channels; Chromatography, High Pressure Liquid; Fermentation; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Mice; Penicillium; Receptors, Cytoplasmic and Nuclear

1993
Adenine-nucleotide binding sites on the inositol 1,4,5-trisphosphate receptor bind caffeine, but not adenophostin A or cyclic ADP-ribose.
    Cell calcium, 1999, Volume: 25, Issue:2

    Topics: Adenine; Adenosine; Adenosine Diphosphate Ribose; Animals; Binding Sites; Caffeine; Calcium; Calcium Channels; Cyclic ADP-Ribose; Dose-Response Relationship, Drug; Inhibitory Concentration 50; Inositol 1,4,5-Trisphosphate Receptors; Mice; Models, Genetic; Protein Binding; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Time Factors

1999
Contribution of the adenine base to the activity of adenophostin A investigated using a base replacement strategy.
    Journal of medicinal chemistry, 2000, Nov-02, Volume: 43, Issue:22

    Topics: Adenine; Adenosine; Animals; Calcium; Calcium Channel Agonists; Calcium Channels; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Liver; Magnetic Resonance Spectroscopy; Membranes; Radioligand Assay; Rats; Receptors, Cytoplasmic and Nuclear; Spectrometry, Mass, Fast Atom Bombardment; Structure-Activity Relationship

2000
Conformational and inframolecular studies of the protonation of adenophostin analogues lacking the adenine moiety.
    Biochimica et biophysica acta, 2004, Mar-17, Volume: 1671, Issue:1-3

    Topics: Adenine; Adenosine; Bacterial Proteins; Calcium Channel Agonists; Inositol 1,4,5-Trisphosphate; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Phosphorus; Phosphorylation; Protein Conformation; Protons

2004
Adenophostin A and analogues modified at the adenine moiety: synthesis, conformational analysis and biological activity.
    Organic & biomolecular chemistry, 2005, Jan-21, Volume: 3, Issue:2

    Topics: Adenine; Adenosine; Animals; Binding Sites; Calcium; Calcium Channels; Cell Line; Chickens; Hydrogen Bonding; Inositol 1,4,5-Trisphosphate Receptors; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Rats; Receptors, Cytoplasmic and Nuclear; Recombinant Proteins; Solutions; Structure-Activity Relationship

2005
Contribution of phosphates and adenine to the potency of adenophostins at the IP₃ receptor: synthesis of all possible bisphosphates of adenophostin A.
    Journal of medicinal chemistry, 2012, Feb-23, Volume: 55, Issue:4

    Topics: Adenine; Adenosine; Animals; Calcium; Cell Line; Chickens; Inositol 1,4,5-Trisphosphate Receptors; Models, Molecular; Organophosphates; Rats; Recombinant Proteins; Stereoisomerism; Structure-Activity Relationship

2012