adenine and wortmannin

adenine has been researched along with wortmannin in 51 studies

Research

Studies (51)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	4 (7.84)	18.2507
2000's	22 (43.14)	29.6817
2010's	24 (47.06)	24.3611
2020's	1 (1.96)	2.80

Authors

Authors	Studies
Wise, H	1
Blommaart, EF; Krause, U; Meijer, AJ; Schellens, JP; Vreeling-Sindelárová, H	1
Carnero, A; Lacal, JC	1
Chiba, K; Hoshi, M; Katada, T; Kontani, K; Kurosu, H; Nakano, T	1
Abbondandolo, A; Bonatti, S; Pigullo, S; Simili, M	1
Kovács, AL; Kovács, J; Pálfia, Z; Réz, G	1
Aragona, F; Malendowicz, LK; Nussdorfer, GG; Rebuffat, P; Tortorella, C	1
Colombo, MI; Munafó, DB	1
Backer, JM; Brachmann, SM; Cooper, J; Eskelinen, EL; Lucocq, JM; Prescott, AR; Tang, X; Wang, L	1
Dick, K; Sadhu, C; Staunton, DE; Tino, WT	1
Lundholt, BK; Pagliaro, L; Scudder, KM	1
Andersson, TP; Sköld, HN; Svensson, SP	1
Fujita, H; Himeno, M; Hirosako, K; Hirota, Y; Imasato, H; Kuronita, T; Masuyama, N; Nishioka, M; Tanaka, Y; Umeda, A	1
Inoue, Y; Matsuoka, K; Moriyasu, Y; Takatsuka, C	1
Al-Adhami, BH; Doenhoff, MJ; Kusel, R; Noble, C; Sharaf, O; Thornhill, J	1
Cui, Q; Ikejima, T; Onodera, S; Tashiro, S	1
Ferreira, AM; Hayflick, JS; Isaacs, H; Rogers, KA; Sandig, M	1
Araki, N; Egami, Y; Hamasaki, M; Hatae, T	1
Chen, SG; Cui, Q; Ikejima, T; Li, D; Onodera, S; Tashiro, S; Wu, LJ	1
Dunn, SR; Schnitzler, CE; Weis, VM	1
Araki, N; Egami, Y	1
Bertone, C; Bianco, MJ; Brama, M; Castelli, A; Rossi, F; Santiemma, V	1
Balduini, W; Buonocore, G; Carloni, S	1
Anwar, T; Beraldi, R; Caselli, G; Di Vito, M; Indelicato, M; Letari, O; Makovec, F; Morgante, E; Pucci, B; Russo, MA; Sale, P; Schito, L; Spadafora, C; Tafani, M	1
Fan, Z; Gao, GF; Hu, X; Jiang, X; Liu, D; Wang, M; Yan, J; Zhou, Z	1
Andina, N; Dahinden, CA; Didichenko, S; Schmidt-Mende, J; Simon, HU	1
Tan, KSW; Ye, AJJ; Yin, J	1
Bauvy, C; Codogno, P; Huang, Q; Ong, CN; Shen, HM; Shui, G; Tan, HL; Wenk, MR; Wu, YT	1
Knight, ZA	1
Chen, D; Hao, Q; Hou, H; Huang, Y; Lv, L; Shi, Q; Yi, Q; Zhang, T; Zhang, Y	1
Cheng, E; Ganaie, SS; Haque, A; Hussein, IT; Mir, MA; Sheema, S; Werle, MJ	1
Cain, RJ; Ridley, AJ; Vanhaesebroeck, B	1
Heckmann, BL; Liu, J; Yang, X; Zhang, X	1
Anand, PK; Buffen, K; Joosten, LAB; Kanneganti, TD; Mennens, S; Netea, MG; Oosting, M; Plantinga, TS; Sturm, P; van de Veerdonk, FL; van der Meer, JWM; Xavier, RJ	1
Anderson, CD; Dorsett-Martin, WA; Drake, LC; Morris, MW; Zhang, J	1
Dickman, MB; Kabbage, M; Williams, B	1
Chang, JY; Chen, KL; Cheung, CHA; Huang, CC	1
Dixon, SJ; Jirik, FR; Kashishian, A; Lannutti, BJ; Pereverzev, A; Puri, KD; Shugg, RP; Sims, SM; Steiner, BH; Tanabe, N; Thomson, A	1
Devine, A; Kacprzyk, J; McCabe, PF	1
Buch, S; Cai, Y; Callen, SE; Guo, ML; Liao, K; Periyasamy, P; Yang, L	1
Bao, Y; Chao, Y; Hamilton, CJ; He, Y; Li, B; Liu, R; Roberts, AA; Sexton, DW; Shan, Y; Wang, W; Wileman, T; Yu, G	1
Barui, AK; Hu, Y; Jin, PP; Lin, J; Patra, CR; Ruan, RQ; Shi, SS; Wei, PF; Wen, LP; Zhang, HR; Zhang, JQ; Zhang, L; Zhang, YJ; Zhou, W	1
Münz, C; Nytko, KJ; Reichenbach, J; Romao, S; Siler, U; Tejera, E	1
Chen, S; Dai, H; Deng, Z; Du, H; Hei, TK; Liu, Y; Nie, Y; Wang, J; Wang, M; Wang, X; Wu, L; Xu, A	1
He, G; Li, C; Li, S; Su, S; Tan, X; Tong, L; Xu, W	1
Baek, E; Kim, CL; Kim, MG; Lee, GM; Lee, JS	1
Lee, JH; Lee, YJ; Moon, JH; Park, SY	1
Cao, T; Chen, C; Fang, W; Gu, Y; Li, X; Shan, Y; Shi, X; Xin, Y; Zhou, Y	1
Fuentes, F; Galletti, JG; Geffner, JR; Gerber, PP; Guzman, M; Iula, L; Jancic, CC; Keitelman, IA; Ostrowski, M; Sabbione, F; Trevani, AS	1
Fang, SH; Fu, YJ; Gao, C; Li, J; Wang, P; Wang, W; Yao, LP; Zhang, J; Zhang, SD	1
Chung, T; Jung, H; Lee, HN	1

Reviews

1 review(s) available for adenine and wortmannin

Article	Year
Small molecule inhibitors of the PI3-kinase family. Current topics in microbiology and immunology, 2010, Volume: 347 Topics: Adenine; Androstadienes; Animals; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Chromones; DNA-Activated Protein Kinase; DNA-Binding Proteins; Humans; Morpholines; Neoplasms; Nuclear Proteins; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Quinazolines; Tumor Suppressor Proteins; Wortmannin	2010

Article

Year

Small molecule inhibitors of the PI3-kinase family.

Current topics in microbiology and immunology, 2010, Volume: 347

Topics: Adenine; Androstadienes; Animals; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Chromones; DNA-Activated Protein Kinase; DNA-Binding Proteins; Humans; Morpholines; Neoplasms; Nuclear Proteins; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Quinazolines; Tumor Suppressor Proteins; Wortmannin

2010

Other Studies

50 other study(ies) available for adenine and wortmannin

Article	Year
The inhibitory effect of prostaglandin E2 on rat neutrophil aggregation. Journal of leukocyte biology, 1996, Volume: 60, Issue:4 Topics: Adenine; Androstadienes; Animals; Ascitic Fluid; Cell Aggregation; Cells, Cultured; Chemotaxis, Leukocyte; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Enzyme Inhibitors; Glyburide; Isoquinolines; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphodiesterase Inhibitors; Phosphotransferases (Alcohol Group Acceptor); Potassium Channels; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Rolipram; Sulfonamides; Wortmannin	1996
The phosphatidylinositol 3-kinase inhibitors wortmannin and LY294002 inhibit autophagy in isolated rat hepatocytes. European journal of biochemistry, 1997, Jan-15, Volume: 243, Issue:1-2 Topics: Adenine; Androstadienes; Animals; Autophagy; Cell Membrane; Cells, Cultured; Chromones; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Enzyme Inhibitors; Liver; Male; Morpholines; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Protein Serine-Threonine Kinases; Rats; Rats, Wistar; Ribosomal Protein S6; Ribosomal Protein S6 Kinases; Ribosomal Proteins; Signal Transduction; Starvation; Wortmannin	1997
Wortmannin, an inhibitor of phosphatidyl-inositol 3-kinase, induces oocyte maturation through a MPF-MAPK-dependent pathway. FEBS letters, 1998, Jan-30, Volume: 422, Issue:2 Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Androstadienes; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Chromones; Cycloheximide; Enzyme Activation; Enzyme Inhibitors; Female; In Vitro Techniques; Kinetics; Maturation-Promoting Factor; Morpholines; Oocytes; Phosphoinositide-3 Kinase Inhibitors; Signal Transduction; Wortmannin; Xenopus laevis	1998
G-protein betagamma subunit-dependent phosphorylation of 62-kDa protein in the early signaling pathway of starfish oocyte maturation induced by 1-methyladenine. Developmental biology, 1999, May-01, Volume: 209, Issue:1 Topics: Adenine; Androstadienes; Animals; Chromones; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; GTP-Binding Proteins; Hydrogen-Ion Concentration; In Vitro Techniques; Microinjections; Morpholines; Oocytes; Phosphatidylinositol 3-Kinases; Phosphorylation; Signal Transduction; Starfish; Time Factors; Wortmannin	1999
Induction of apoptosis and inhibition of signalling pathways by alkylated purines. Mutagenesis, 2000, Volume: 15, Issue:4 Topics: Adenine; Alkylation; Androstadienes; Animals; Antibiotics, Antineoplastic; Apoptosis; Cell Line; Cricetinae; DNA Fragmentation; Electrophoresis, Agar Gel; Enzyme Inhibitors; Fibroblasts; G1 Phase; Genes, p53; Guanine; MAP Kinase Signaling System; Mutation; Phosphorylation; Purines; Resting Phase, Cell Cycle; Ribosomal Protein S6 Kinases; Signal Transduction; Sirolimus; Wortmannin	2000
Autophagy in the epithelial cells of murine seminal vesicle in vitro. Formation of large sheets of nascent isolation membranes, sequestration of the nucleus and inhibition by wortmannin and 3-ethyladenine. Cell and tissue research, 2000, Volume: 302, Issue:2 Topics: Adenine; Androstadienes; Animals; Autophagy; Cell Nucleus; Cell Size; Detergents; Endoplasmic Reticulum, Rough; Epithelial Cells; In Vitro Techniques; Intracellular Membranes; Male; Mice; Microscopy, Electron; Octoxynol; Phosphoinositide-3 Kinase Inhibitors; Seminal Vesicles; Vacuoles; Wortmannin	2000
Signaling pathways involved in the A and B receptor-mediated cortisol secretagogue effect of endothelins in the human adrenal cortex. International journal of molecular medicine, 2001, Volume: 7, Issue:3 Topics: Adenine; Androstadienes; Cells, Cultured; Endothelin Receptor Antagonists; Endothelins; Enzyme Inhibitors; Estrenes; Flavonoids; Humans; Hydrocortisone; Indomethacin; Naphthalenes; Nifedipine; Oligopeptides; Peptides, Cyclic; Phosphoinositide-3 Kinase Inhibitors; Piperidines; Protein Kinase C; Pyrazoles; Pyrrolidinones; Receptors, Endothelin; Signal Transduction; Type C Phospholipases; Tyrphostins; Wortmannin; Zona Fasciculata; Zona Reticularis	2001
A novel assay to study autophagy: regulation of autophagosome vacuole size by amino acid deprivation. Journal of cell science, 2001, Volume: 114, Issue:Pt 20 Topics: Adenine; Amino Acids; Androstadienes; Animals; Autophagy; Cadaverine; CHO Cells; Cricetinae; Cycloheximide; Enzyme Inhibitors; Ethylmaleimide; Fluorescent Dyes; Phagosomes; Protein Synthesis Inhibitors; Recombinant Fusion Proteins; Vacuoles; Vinblastine; Wortmannin	2001
Inhibition of autophagy in mitotic animal cells. Traffic (Copenhagen, Denmark), 2002, Volume: 3, Issue:12 Topics: Adenine; Anaphase; Androstadienes; Animals; Autophagy; Blotting, Western; Cell Line; Chromones; Endoplasmic Reticulum; Enzyme Inhibitors; Golgi Apparatus; HeLa Cells; Humans; Immunohistochemistry; Metaphase; Microscopy, Immunoelectron; Microscopy, Phase-Contrast; Mitosis; Morpholines; Nocodazole; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinases; Rats; Ribosomal Protein S6 Kinases, 70-kDa; Sirolimus; Telophase; Time Factors; TOR Serine-Threonine Kinases; Wortmannin	2002
Selective role of PI3K delta in neutrophil inflammatory responses. Biochemical and biophysical research communications, 2003, Sep-05, Volume: 308, Issue:4 Topics: Adenine; Androstadienes; Animals; Anti-Inflammatory Agents; Chromones; Class I Phosphatidylinositol 3-Kinases; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Exocytosis; Inflammation; Leukocyte Elastase; Mice; Mice, Inbred BALB C; Morpholines; Neutrophils; Phosphatidylinositol 3-Kinases; Protein Isoforms; Quinazolines; Signal Transduction; Superoxides; Time Factors; Wortmannin	2003
A simple technique for reducing edge effect in cell-based assays. Journal of biomolecular screening, 2003, Volume: 8, Issue:5 Topics: Adenine; Androstadienes; Animals; Cell Culture Techniques; Cell Division; CHO Cells; Cricetinae; Cytochalasin B; Gentian Violet; Green Fluorescent Proteins; Humans; Luminescent Proteins; Nocodazole; Receptor, Insulin; Temperature; Wortmannin	2003
Phosphoinositide 3-kinase is involved in Xenopus and Labrus melanophore aggregation. Cellular signalling, 2003, Volume: 15, Issue:12 Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Androstadienes; Animals; Chromones; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Dose-Response Relationship, Drug; Kinetics; Melanocyte-Stimulating Hormones; Melanophores; Melanosomes; Melatonin; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Norepinephrine; Papaverine; Perciformes; Phosphatidylinositol 3-Kinases; Phosphodiesterase Inhibitors; Phosphoinositide-3 Kinase Inhibitors; Phosphoric Diester Hydrolases; Phosphorylation; Rolipram; Signal Transduction; Wortmannin; Xenopus laevis	2003
3-Methyladenine specifically inhibits retrograde transport of cation-independent mannose 6-phosphate/insulin-like growth factor II receptor from the early endosome to the TGN. Biochemical and biophysical research communications, 2004, Apr-09, Volume: 316, Issue:3 Topics: Adenine; Androstadienes; Animals; Biological Transport; Cations; Cell Line; Chromones; Endosomes; Enzyme Inhibitors; Liver; Lysosomes; Mannosephosphates; Microscopy, Fluorescence; Morpholines; Phosphatidylinositol 3-Kinases; Rats; Receptor, IGF Type 2; Subcellular Fractions; Time Factors; trans-Golgi Network; Transferrin; Wortmannin	2004
3-methyladenine inhibits autophagy in tobacco culture cells under sucrose starvation conditions. Plant & cell physiology, 2004, Volume: 45, Issue:3 Topics: Adenine; Androstadienes; Autophagy; Cell Death; Cells, Cultured; Endopeptidases; Enzyme Inhibitors; Lysosomes; Microscopy, Electron; Nicotiana; Phosphoinositide-3 Kinase Inhibitors; Plant Proteins; Sucrose; Vacuoles; Wortmannin	2004
The role of acidic organelles in the development of schistosomula of Schistosoma mansoni and their response to signalling molecules. Parasitology, 2005, Volume: 130, Issue:Pt 3 Topics: Adenine; Androstadienes; Animals; Energy Metabolism; Ethylmaleimide; Helminth Proteins; Life Cycle Stages; Organelles; Schistosoma mansoni; Staining and Labeling; Wortmannin	2005
Augmentation of oridonin-induced apoptosis observed with reduced autophagy. Journal of pharmacological sciences, 2006, Volume: 101, Issue:3 Topics: Adenine; Androstadienes; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; bcl-2-Associated X Protein; Cell Proliferation; Diterpenes; Diterpenes, Kaurane; Dose-Response Relationship, Drug; HeLa Cells; Humans; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Sirtuin 1; Sirtuins; Time Factors; Wortmannin	2006
The p110delta isoform of PI3K differentially regulates beta1 and beta2 integrin-mediated monocyte adhesion and spreading and modulates diapedesis. Microcirculation (New York, N.Y. : 1994), 2006, Volume: 13, Issue:6 Topics: Adenine; Androstadienes; CD18 Antigens; cdc42 GTP-Binding Protein; Cell Line; Cell Movement; Chromones; Class I Phosphatidylinositol 3-Kinases; Gene Expression Regulation; Humans; Integrin alpha4beta1; Integrin beta1; Intercellular Adhesion Molecule-1; Lymphocyte Function-Associated Antigen-1; Monocytes; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Quinazolines; rac1 GTP-Binding Protein; Signal Transduction; Vascular Cell Adhesion Molecule-1; Wortmannin	2006
Effect of 3-methyladenine on the fusion process of macropinosomes in EGF-stimulated A431 cells. Cell structure and function, 2006, Volume: 31, Issue:2 Topics: Adenine; Androstadienes; Cell Line, Tumor; Chromones; Enzyme Inhibitors; Epidermal Growth Factor; Epithelial Cells; Gene Expression Regulation; Gene Expression Regulation, Enzymologic; Humans; Membrane Fusion; Membrane Proteins; Morpholines; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates; Pinocytosis; Vesicular Transport Proteins; Wortmannin	2006
Inactivation of ras and changes of mitochondrial membrane potential contribute to oridonin-induced autophagy in a431 cells. Journal of pharmacological sciences, 2007, Volume: 105, Issue:1 Topics: Adenine; Androstadienes; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; bcl-2-Associated X Protein; bcl-X Protein; Beclin-1; Cell Line, Tumor; Cell Proliferation; Diterpenes; Diterpenes, Kaurane; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Flow Cytometry; Humans; Indoles; Membrane Potential, Mitochondrial; Membrane Proteins; Microtubule-Associated Proteins; Molecular Structure; Phenols; Phosphatidylethanolamines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Polyenes; Polyunsaturated Alkamides; Proto-Oncogene Proteins c-raf; ras Proteins; Wortmannin	2007
Apoptosis and autophagy as mechanisms of dinoflagellate symbiont release during cnidarian bleaching: every which way you lose. Proceedings. Biological sciences, 2007, Dec-22, Volume: 274, Issue:1629 Topics: Adenine; Amino Acid Chloromethyl Ketones; Androstadienes; Animals; Apoptosis; Autophagy; Dinoflagellida; Dose-Response Relationship, Drug; Hot Temperature; RNA Interference; Sea Anemones; Sirolimus; Symbiosis; Wortmannin	2007
Characterization of Rab21-positive tubular endosomes induced by PI3K inhibitors. Experimental cell research, 2008, Feb-15, Volume: 314, Issue:4 Topics: Adenine; Androstadienes; Cell Line, Tumor; Endosomes; Enzyme Inhibitors; Humans; Microscopy, Fluorescence; Microtubules; Phosphoinositide-3 Kinase Inhibitors; rab GTP-Binding Proteins; Wortmannin	2008
Ghrelin induces proliferation in human aortic endothelial cells via ERK1/2 and PI3K/Akt activation. Peptides, 2008, Volume: 29, Issue:11 Topics: Adenine; Androstadienes; Aorta; Carbazoles; Cell Proliferation; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Flavonoids; Ghrelin; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrroles; Wortmannin	2008
Protective role of autophagy in neonatal hypoxia-ischemia induced brain injury. Neurobiology of disease, 2008, Volume: 32, Issue:3 Topics: Adenine; Analysis of Variance; Androstadienes; Animals; Animals, Newborn; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Blotting, Western; Cell Count; Cerebral Cortex; Hippocampus; Hypoxia-Ischemia, Brain; Immunohistochemistry; In Situ Nick-End Labeling; Necrosis; Neurons; Rats; Rats, Sprague-Dawley; Simvastatin; Sirolimus; Wortmannin	2008
Induction of autophagic cell death by a novel molecule is increased by hypoxia. Autophagy, 2008, Volume: 4, Issue:8 Topics: Adenine; Amidines; Androstadienes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Autophagy; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Mice, Transgenic; Microtubule-Associated Proteins; Neoplasms; Phagosomes; Thiourea; Trifluoperazine; Vascular Endothelial Growth Factor A; Wortmannin	2008
Autophagy is involved in influenza A virus replication. Autophagy, 2009, Volume: 5, Issue:3 Topics: Adenine; Androstadienes; Animals; Autophagy; Cell Survival; Dogs; Humans; Influenza A virus; Microscopy, Fluorescence; Microtubule-Associated Proteins; Microtubules; Models, Biological; RNA; RNA Interference; RNA, Small Interfering; Virus Replication; Wortmannin	2009
Proviral integration site for Moloney murine leukemia virus 1, but not phosphatidylinositol-3 kinase, is essential in the antiapoptotic signaling cascade initiated by IL-5 in eosinophils. The Journal of allergy and clinical immunology, 2009, Volume: 123, Issue:3 Topics: Adenine; Androstadienes; Apoptosis; Cells, Cultured; Chromones; Eosinophils; Humans; Hypersensitivity; Interleukin-5; Janus Kinase 2; Microscopy, Confocal; Morpholines; Myeloid Cell Leukemia Sequence 1 Protein; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-pim-1; Quinazolines; Tyrphostins; Wortmannin; Xanthenes	2009
Autophagy is involved in starvation response and cell death in Blastocystis. Microbiology (Reading, England), 2010, Volume: 156, Issue:Pt 3 Topics: Adenine; Androstadienes; Autophagy; Blastocystis; Microscopy, Confocal; Microscopy, Electron, Transmission; Sirolimus; Vacuoles; Wortmannin	2010
Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3-kinase. The Journal of biological chemistry, 2010, Apr-02, Volume: 285, Issue:14 Topics: Adenine; Androstadienes; Animals; Autophagy; Autophagy-Related Protein 7; Blotting, Western; Embryo, Mammalian; Fibroblasts; Immunoprecipitation; Lysosomes; Mice; Microtubule-Associated Proteins; Phagosomes; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates; Phosphodiesterase Inhibitors; Phosphoinositide-3 Kinase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Wortmannin	2010
Inhibitors of phosphatidylinositol 3'-kinases promote mitotic cell death in HeLa cells. PloS one, 2012, Volume: 7, Issue:4 Topics: Adenine; Androstadienes; Animals; Caspase 3; Cell Cycle Checkpoints; Cell Death; Cell Line; Cell Survival; Fibroblasts; HeLa Cells; Humans; Mice; Neoplasms; Phosphoinositide-3 Kinase Inhibitors; Wortmannin	2012
Autophagic clearance of Sin Nombre hantavirus glycoprotein Gn promotes virus replication in cells. Journal of virology, 2012, Volume: 86, Issue:14 Topics: Adenine; Androstadienes; Animals; Autophagy; Autophagy-Related Protein 7; Cell Line; Chlorocebus aethiops; Chromones; Glycoproteins; HeLa Cells; Humans; Morpholines; Proteolysis; RNA Interference; RNA, Small Interfering; Sin Nombre virus; Ubiquitin-Activating Enzymes; Vero Cells; Viral Envelope Proteins; Virus Replication; Wortmannin	2012
Different PI 3-kinase inhibitors have distinct effects on endothelial permeability and leukocyte transmigration. The international journal of biochemistry & cell biology, 2012, Volume: 44, Issue:11 Topics: Adenine; Androstadienes; Antigens, CD; Cadherins; Capillary Permeability; Cell Membrane Permeability; Cell Shape; Class Ia Phosphatidylinositol 3-Kinase; Dioxoles; Endothelial Cells; Focal Adhesion Kinase 2; Furans; Human Umbilical Vein Endothelial Cells; Humans; Leukocytes; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Binding; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyridines; Pyrimidines; Quinazolines; Signal Transduction; Thiazolidinediones; TOR Serine-Threonine Kinases; Transendothelial and Transepithelial Migration; Tumor Necrosis Factor-alpha; Wortmannin	2012
The autophagic inhibitor 3-methyladenine potently stimulates PKA-dependent lipolysis in adipocytes. British journal of pharmacology, 2013, Volume: 168, Issue:1 Topics: 3T3-L1 Cells; Adenine; Adipocytes; Androstadienes; Animals; Autophagy; Hydrolysis; Lipase; Lipolysis; Mice; Phosphoinositide-3 Kinase Inhibitors; RNA, Small Interfering; Signal Transduction; Sterol Esterase; Triglycerides; Wortmannin	2013
Autophagy modulates Borrelia burgdorferi-induced production of interleukin-1β (IL-1β). The Journal of biological chemistry, 2013, Mar-22, Volume: 288, Issue:12 Topics: Adenine; Androstadienes; Autophagy; Borrelia burgdorferi; Caspase 1; Cells, Cultured; Enzyme Activation; Host-Pathogen Interactions; Humans; Inflammation Mediators; Interleukin 1 Receptor Antagonist Protein; Interleukin-1beta; Interleukin-6; Leukocytes, Mononuclear; Reactive Oxygen Species; Receptors, Interleukin-1; Tumor Necrosis Factor-alpha; Wortmannin	2013
Autophagy is involved in endoplasmic reticulum stress-induced cell death of rat hepatocytes. The Journal of surgical research, 2013, Volume: 183, Issue:2 Topics: Adenine; Androstadienes; Animals; Apoptosis; Autophagy; Cell Survival; Cells, Cultured; Disease Models, Animal; Endoplasmic Reticulum Stress; Fatty Liver; Hepatocytes; Male; Rats; Rats, Zucker; Taurochenodeoxycholic Acid; Tunicamycin; Wortmannin	2013
Cell death control: the interplay of apoptosis and autophagy in the pathogenicity of Sclerotinia sclerotiorum. PLoS pathogens, 2013, Volume: 9, Issue:4 Topics: Adenine; Androstadienes; Antifungal Agents; Apoptosis; Arabidopsis; Ascomycota; Autophagy; Chloroquine; Chromones; Host-Pathogen Interactions; Morpholines; Mycoses; Oxalic Acid; Plant Diseases; Reactive Oxygen Species; Respiratory Burst; Wortmannin	2013
Autophagy induced by cathepsin S inhibition induces early ROS production, oxidative DNA damage, and cell death via xanthine oxidase. Free radical biology & medicine, 2013, Volume: 65 Topics: Adenine; Androstadienes; Antigen Presentation; Apoptosis; Autophagy; Autophagy-Related Protein 5; Autophagy-Related Protein 7; Cathepsins; Cell Line, Tumor; Cell Survival; DNA Damage; Humans; Microtubule-Associated Proteins; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; Ubiquitin-Activating Enzymes; Wortmannin; Xanthine Oxidase	2013
Effects of isoform-selective phosphatidylinositol 3-kinase inhibitors on osteoclasts: actions on cytoskeletal organization, survival, and resorption. The Journal of biological chemistry, 2013, Dec-06, Volume: 288, Issue:49 Topics: Adenine; Androstadienes; Animals; Bone Resorption; Cell Survival; Chromones; Cytoskeleton; Indazoles; Isoenzymes; Morpholines; Osteoclasts; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Quinazolines; Rabbits; RANK Ligand; Rats; Sulfonamides; Wortmannin	2013
The root hair assay facilitates the use of genetic and pharmacological tools in order to dissect multiple signalling pathways that lead to programmed cell death. PloS one, 2014, Volume: 9, Issue:4 Topics: Adenine; Androstadienes; Apoptosis; Arabidopsis; Arabidopsis Proteins; Autophagy; Biological Assay; Fumonisins; Gibberellins; Hot Temperature; Hydrogen Peroxide; Indans; Mitochondrial Swelling; Models, Biological; Mutation; Mycotoxins; Organophosphonates; Phenylalanine Ammonia-Lyase; Plant Roots; Salicylic Acid; Signal Transduction; Sodium Chloride; Stress, Physiological; Wortmannin	2014
Cocaine-mediated microglial activation involves the ER stress-autophagy axis. Autophagy, 2015, Volume: 11, Issue:7 Topics: Adenine; Androstadienes; Animals; Apoptosis Regulatory Proteins; Autophagy; Autophagy-Related Protein 5; Beclin-1; Biomarkers; Cell Line; Cell Survival; Cocaine; Endoplasmic Reticulum Stress; Mice, Inbred C57BL; Microglia; Models, Biological; Phagosomes; Phosphatidylinositol 3-Kinases; Protein Kinase Inhibitors; Proteins; Rats; Reactive Oxygen Species; RNA, Small Interfering; Signal Transduction; Time Factors; Wortmannin	2015
Sulforaphane Protects the Liver against CdSe Quantum Dot-Induced Cytotoxicity. PloS one, 2015, Volume: 10, Issue:9 Topics: Adenine; Androstadienes; Animals; Autophagy; Cadmium Compounds; Cell Death; Cell Line; Gene Knockdown Techniques; Glutathione; Humans; Intracellular Signaling Peptides and Proteins; Intracellular Space; Isothiocyanates; Kelch-Like ECH-Associated Protein 1; Liver; Metallothionein; Mice, Inbred ICR; NF-E2-Related Factor 2; Protective Agents; Quantum Dots; RNA, Messenger; Selenium Compounds; Sulfoxides; Transcription, Genetic; Wortmannin	2015
Differential ERK activation during autophagy induced by europium hydroxide nanorods and trehalose: Maximum clearance of huntingtin aggregates through combined treatment. Biomaterials, 2015, Volume: 73 Topics: Adenine; Androstadienes; Animals; Autophagy; Autophagy-Related Protein 5; Butadienes; Cell Line, Tumor; Cell Survival; Chloroquine; Europium; Extracellular Signal-Regulated MAP Kinases; Green Fluorescent Proteins; HeLa Cells; Humans; Huntingtin Protein; Hydroxides; Lysosomes; Macrolides; Mice; Microscopy, Fluorescence; Microtubule-Associated Proteins; Nanotubes; Nerve Tissue Proteins; Neurodegenerative Diseases; Nitriles; Phagosomes; Phosphorylation; RNA, Small Interfering; Signal Transduction; TOR Serine-Threonine Kinases; Trehalose; Wortmannin	2015
Defective nuclear entry of hydrolases prevents neutrophil extracellular trap formation in patients with chronic granulomatous disease. The Journal of allergy and clinical immunology, 2015, Volume: 136, Issue:6 Topics: Adenine; Androstadienes; Benzylamines; Candida albicans; Cell Nucleus; Extracellular Traps; Granulomatous Disease, Chronic; Histones; Humans; Hydrolases; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Quinazolines; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Wortmannin	2015
Graphene Oxide Attenuates the Cytotoxicity and Mutagenicity of PCB 52 via Activation of Genuine Autophagy. Environmental science & technology, 2016, Mar-15, Volume: 50, Issue:6 Topics: Adenine; Androstadienes; Animals; Autophagy; CD59 Antigens; Cell Line; Cricetinae; Graphite; Humans; Hybrid Cells; Mutagens; Oxides; Polychlorinated Biphenyls; Sirolimus; Trehalose; Wortmannin	2016
Gadd45b prevents autophagy and apoptosis against rat cerebral neuron oxygen-glucose deprivation/reperfusion injury. Apoptosis : an international journal on programmed cell death, 2016, Volume: 21, Issue:4 Topics: Adenine; Androstadienes; Animals; Antigens, Differentiation; Apoptosis; Autophagy; Brain Ischemia; Cells, Cultured; Cerebral Cortex; Glucose; Neurons; Oxygen; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Wortmannin	2016
Chemical inhibition of autophagy: Examining its potential to increase the specific productivity of recombinant CHO cell lines. Biotechnology and bioengineering, 2016, Volume: 113, Issue:9 Topics: Adenine; Androstadienes; Animals; Autophagy; Bioreactors; Cell Culture Techniques; CHO Cells; Chromones; Cricetinae; Cricetulus; Morpholines; Recombinant Proteins; Wortmannin	2016
Hinokitiol protects primary neuron cells against prion peptide-induced toxicity via autophagy flux regulated by hypoxia inducing factor-1. Oncotarget, 2016, May-24, Volume: 7, Issue:21 Topics: Adenine; Androstadienes; Animals; Apoptosis; Autophagy; Autophagy-Related Protein 5; Cells, Cultured; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; In Situ Nick-End Labeling; Mice; Microscopy, Electron, Transmission; Monoterpenes; Neurons; Neuroprotective Agents; Peptide Fragments; Primary Cell Culture; Prion Diseases; Prions; Protein Kinase Inhibitors; RNA Interference; RNA, Small Interfering; Signal Transduction; Tropolone; Wortmannin	2016
Porcine teschovirus 2 induces an incomplete autophagic response in PK-15 cells. Archives of virology, 2018, Volume: 163, Issue:3 Topics: Adenine; Androstadienes; Animals; Autophagy; Autophagy-Related Protein 5; Cell Line; Epithelial Cells; Gene Expression Regulation; Genes, Reporter; Green Fluorescent Proteins; Host-Pathogen Interactions; Kidney; Microtubule-Associated Proteins; RNA, Small Interfering; Signal Transduction; Sirolimus; Swine; Teschovirus; Virus Replication; Wortmannin	2018
Autophagy Mediates Interleukin-1β Secretion in Human Neutrophils. Frontiers in immunology, 2018, Volume: 9 Topics: Adenine; Adenosine Triphosphate; Autophagy; Autophagy-Related Protein 5; Cell Line; Humans; Inflammation Mediators; Interleukin-1beta; Lipopolysaccharides; Macrolides; Microtubule-Associated Proteins; Neutrophils; Protein Transport; RNA, Small Interfering; Secretory Pathway; Serine Proteases; Wortmannin	2018
Juglone induces apoptosis and autophagy via modulation of mitogen-activated protein kinase pathways in human hepatocellular carcinoma cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2018, Volume: 116, Issue:Pt B Topics: Acetylcysteine; Adenine; Amino Acid Chloromethyl Ketones; Androstadienes; Apoptosis; Autophagy; Carcinoma, Hepatocellular; Cell Cycle Checkpoints; Cell Proliferation; Enzyme Activation; Hep G2 Cells; Humans; Liver Neoplasms; MAP Kinase Kinase 4; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Naphthoquinones; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Reactive Oxygen Species; Wortmannin	2018
Subcellular Localization of PI3P in Arabidopsis. Methods in molecular biology (Clifton, N.J.), 2020, Volume: 2177 Topics: Adenine; Arabidopsis; Arabidopsis Proteins; Endosomes; Phosphatidylinositol Phosphates; Protein Transport; Vesicular Transport Proteins; Wortmannin	2020