adenine has been researched along with uric acid in 186 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 127 (68.28) | 18.7374 |
| 1990's | 8 (4.30) | 18.2507 |
| 2000's | 15 (8.06) | 29.6817 |
| 2010's | 23 (12.37) | 24.3611 |
| 2020's | 13 (6.99) | 2.80 |
| Authors | Studies |
|---|---|
| Bearne, SL; Lunn, FA; Roy, AC | 1 |
| Einhorn, R; Franki, N; Hays, RM; Levine, SD | 1 |
| Hanks, AR; Magill, CW; Magill, JM; Sabina, RL | 1 |
| Berlin, RD; Oliver, JM | 1 |
| Davis, BB; Zenser, TV | 1 |
| Chan, TS | 1 |
| Simmonds, HA | 2 |
| Edwards, NL; Fox, IH; Recker, D | 1 |
| Ciompi, ML; Lucacchini, A; Mazzoni, MR; Segnini, D | 1 |
| Dousset, N; Douste-Blazy, L; Solera, ML; Valdiguie, P | 1 |
| Arkell, DG; Barratt, TM; Cameron, JS; Potter, CF; Rose, GA; Sahota, A; Simmonds, HA; Van Acker, KJ; Williams, DI | 1 |
| Schatz, RA; Sellinger, OZ; Vunnam, CR | 1 |
| Cameron, JS; Simmonds, HA; Van Acker, KJ | 1 |
| Cadenhead, A; Cameron, JS; Farebrother, D; Simmonds, HA | 1 |
| Cameron, JS; McBurney, A; Simmonds, HA; Van Acker, KJ | 1 |
| Cameron, JS; Potter, C; Simmonds, HA; Van Acker, KJ | 1 |
| Badenoch-Jones, P; Buttery, PJ | 1 |
| Bryant, WF; Klein, PD | 1 |
| Künzer, W | 1 |
| Lohmann, W; Sapper, H; Schimmack, W | 1 |
| Lohmann, W; Schimmack, W | 1 |
| Maddocks, JL | 1 |
| Addison, GM; Ward, ID | 1 |
| Brulé, D; Sarwar, G; Savoie, L | 1 |
| Ishii, T; Karasawa, Y; Kubota, T | 1 |
| Camiña, F; Castro-Gago, M; Lojo, S; Rodríguez-Núñez, A; Rodríguez-Segade, S | 1 |
| Gómez, PF; Jiménez, ML; Mantilla, JG; Mateos, FA; Puig, JG; Ramos, TH | 1 |
| Barratt, TM; Cameron, JS; Dillon, MJ; Meadow, SR; Simmonds, HA; Trompeter, RS | 1 |
| Maddocks, JL; Reed, T | 1 |
| Ho, YK; Li, WC | 1 |
| Ruopuro, ML; Usenius, JP; Usenius, R | 1 |
| Brulé, D; Campbell, J; Sarwar, G; Savoie, L; Van Zeggelaar, M | 1 |
| Kamatani, N; Kitamura, M; Kojima, T; Nishina, T; Nishioka, K | 1 |
| Fox, IH; Jiménez, ML; Mateos, FA; Puig, JG | 1 |
| Betz, AL | 1 |
| Fox, IH | 1 |
| Biesbroek, AL; De Kievit, H; Middelhoven, WJ | 1 |
| Bührdel, P; Hirschberg, K; Krüger, W; Wehnert, M | 1 |
| Schäfer, R; Schwartz, AC | 1 |
| Monnens, LA; Schretlen, ED; van der Zee, SP | 1 |
| Davis, W; Kibbey, AH | 1 |
| Isshiki, G; Oura, T; Tada, K; Uesaki, T | 1 |
| Matsuzaki, F; Raben, MS | 1 |
| Fox, IH; Greene, ML; Kelley, WN; Levy, RI; Rosenbloom, FM; Seegmiller, JE | 1 |
| Fox, IH; Kelley, WN | 4 |
| Phelps, P; Tse, RL; Urban, D | 1 |
| Bakay, B; Borden, M; Nyhan, WL | 1 |
| Becker, MA; Kostel, PJ; Meyer, LJ; Seegmiller, JE | 1 |
| Emmerson, BT; Gordon, RB; Thompson, L | 3 |
| Blair, DG | 1 |
| Hanisch, ME; Lawrence, AL | 1 |
| Jezewska, MM | 1 |
| Hitier, Y | 1 |
| Andrews, TM; Brown, E; Griffiths, MI; McKeran, RO; Watts, RW | 1 |
| Fox, RM; O'Sullivan, WJ; Reye, C; Vincent, L; Wood, MH | 1 |
| Caen, JP; Jenkins, CS; Pokutecky, J; Vainer, H | 1 |
| Becker, MA; Seegmiller, JE | 1 |
| Banfalvi, M; Crawhall, JC; Itiaba, K | 2 |
| Shavlovskii, GM; Sibirnyi, AA | 1 |
| Demus, A; Kaiser, W; Schaub, J | 1 |
| de Bruyn, CH; Geerdink, RA; Lommen, EJ; Oei, TL | 1 |
| Fox, IH; Kelley, WN; Meade, JC | 1 |
| Amor, B; Auscher, C; de Gery, A; Delbarre, F | 1 |
| Baker, DH; Molitoris, BA | 1 |
| Chang, GN; Fam, A; Little, AH; Malkin, A | 1 |
| Auscher, C; Delbarre, F; Mercier, N; Pasquier, C | 1 |
| Ceccarelli, M; Ciompi, ML; Pasero, G | 1 |
| Amor, B; Auscher, C; Cartier, P; de Gery, A; Delbarre, F; Hamet, M | 1 |
| Greene, ML; Henderson, JF; Kelley, WN; Rosenbloom, FM; Seegmiller, JE | 1 |
| Nolfi, JR | 1 |
| Camakaris, J; Cotton, RG; Danks, DM | 1 |
| Benke, PJ; Herrick, N | 1 |
| Boyle, JA; Greene, ML; Seegmiller, JE | 1 |
| Brandes, R; Roth, HJ | 1 |
| Balis, ME; Berman, PH; Cox, RP; Dancis, J; Jansen, V | 1 |
| Kolassa, N; Pfleger, K; Rummel, W | 1 |
| Lommen, EJ; Schretlen, ED; Trijbels, JM; van der Zee, SP | 1 |
| Auscher, C; Cartier, P; de Géry, A; Delbarre, F; Hamet, M | 1 |
| Astrin, KH; Boyle, JA; Graf, ML; Jacobsen, CB; Raivio, KO; Schulman, JD; Seegmiller, JE | 1 |
| Frost, P; Nyhan, WL; Weinstein, GD | 1 |
| Kelley, WN; Wyngaarden, JB | 1 |
| Schwarz, E | 1 |
| Chow, DC; Kawahara, FS; Saunders, T; Sorensen, LB | 1 |
| Bozal, J; Calvet, F; Escarmís, C | 1 |
| Davison, AN; Eyre, C; Scott, JT | 1 |
| Bozal, J; Calvet, F; Domingo, E | 1 |
| Kelley, WN; Miller, J; Rosenbloom, FM; Seegmiller, JE | 1 |
| Duggan, DE; Elfenbein, G; Pua, KH | 1 |
| Weiner, LM; Welsh, BA; Zak, B | 1 |
| Balish, E; Svihla, G | 1 |
| Berlin, RD; Hawkins, RA | 1 |
| Fritsche, W; Reinbothe, H; Schlee, D | 1 |
| Balis, ME; Berman, PH; Dancis, J | 1 |
| Berlin, RD | 1 |
| Diamond, HS; Friedland, M; Halberstam, D; Kaplan, D | 1 |
| James, JA; Nelson, LG; Nyhan, WL; Sweetman, L; Teberg, AJ | 1 |
| Allam, AM; Elzainy, TA | 1 |
| Watts, RW | 1 |
| Gehl, A; Rink, M | 1 |
| Logvinenko, EM; Shavlovskiĭ, GM | 1 |
| Garrison, WM; Holian, J | 1 |
| Alexander, CS; Nagasawa, HT; Swingle, KF | 1 |
| Borghini, F; Ronca-Testoni, S | 1 |
| Burns, RA; Buttery, PJ | 2 |
| Emori, T; Nagase, S | 1 |
| Holliss, DG; Humphrey, SM; Seelye, RN | 1 |
| Hoogkamer-Te Niet, MC; Kreger-Van Rij, NJ; Middelhoven, WJ | 1 |
| Parsons, DS; Shaw, MI | 1 |
| Bach, D; Dewes, W; Schneeberger, W; Zilliken, F | 1 |
| Doppler, W; Joost, J | 1 |
| Okada, T; Oura, H; Yokozawa, T | 1 |
| de Bruyn, CH; Kulakowski, S; Renoirte, P | 1 |
| Cameron, JS; Dillon, MJ; Farebrother, DA; Pincott, JR; Simmons, HA; Warren, DJ | 1 |
| de Bruyn, CH; Kulakowski, S; Müller, MM; Renoirte, P; van Bennekom, CA | 1 |
| Edwards, NL; Fox, IH; Recker, DP | 1 |
| Barratt, TM; Cameron, JS; Dillon, M; Sahota, A; Simmonds, HA; Van Acker, KJ; Webster, DR | 1 |
| de Miguel, E; Gil, A; Mateos, FA; Miranda, ME; Pérez de Ayala, C; Puig, JG; Torres, RJ | 1 |
| Grauel, EL; Grune, T; Schmidt, H; Siems, WG | 1 |
| Cascante, M; Curto, R; Sorribas, A; Voit, EO | 1 |
| Bromberg, Y; Feinstein, S; Frishberg, Y; Sperling, O; Zoref-Shani, E | 1 |
| Camp, DM; Harel, E; Juneau, PL; LeWitt, PA; Loeffler, DA | 1 |
| Kozai, S; Maruyama, T; Sasaki, F | 1 |
| Amillis, S; Diallinas, G; Koukaki, M | 1 |
| Bain, D; Castro, M; Fairbanks, LD; Larregina, A; Lowenstein, P; Morelli, A; Simmonds, HA; Southgate, T | 1 |
| Gröbner, W; Walter-Sack, I | 1 |
| Arezzini, L; Frosi, B; Marinello, E; Pizzichini, M; Porcelli, B; Terzuoli, L | 1 |
| KRANEN-FIEDLER, U | 1 |
| BLAIR, AE; LASTER, L; SEEGMILLER, JE; WYNGAARDEN, JB | 1 |
| JEFFREY, JJ; SCHANKER, LS; TOCCO, DJ | 1 |
| AOKI, A; IBUKI, F; MATSUSHITA, S | 1 |
| AMMANN, EC; LYNCH, VH | 2 |
| CAILLET, J; CLAVERIE, P; PULLMAN, B | 1 |
| AYVAZIAN, JH; SKUPP, S | 1 |
| LASSEN, UV; OVERGAARD-HANSEN, K | 1 |
| Amillis, S; Cecchetto, G; Diallinas, G; Drevet, C; Scazzocchio, C | 1 |
| Samuell, C; Stower, M; Wilkinson, H | 1 |
| Innami, S; Koguchi, H; Koguchi, T; Maekawa, A; Nakajima, H; Tadokoro, T; Takano, S; Yamamoto, Y | 1 |
| Endou, H; Hosoyamada, M; Kamatani, N; Taniguchi, A; Urano, W; Yamanaka, H; Yamanaka, M | 1 |
| Hanabusa, H; Kinai, E | 1 |
| Kou, Y; Li, M; Liu, H; Shao, Y; Ye, T; Zhao, Y; Zhu, Z; Zhuang, Q | 1 |
| Bogner, J; Claas, GJ; Goebel, FD; Jülg, B | 1 |
| Jena, G; Kalra, S; Mukhopadhyay, AK; Tikoo, K | 1 |
| Chong, WH; Collins, MT; Gara, N; Ghany, MG; Hoofnagle, JH; Jake Liang, T; Kleiner, DE; Zhao, X | 1 |
| Abacı, S; Erdem, A; Kuralay, F; Ozyörük, H | 1 |
| Broderick, E; Hotta, MT; Wyatt, CM | 1 |
| Bai, X; Ren, L; Yang, X; Zhang, H; Zhang, S | 1 |
| Chen, CH; Lin, MS; Lin, YT | 1 |
| Baronian, K; Bode, R; Cordes, A; Hoferichter, P; Jankowska, D; Klein, C; Kunze, G; Matros, A; Mock, HP; Trautwein-Schult, A | 1 |
| Chen, S; Liu, X; Lu, Q; Ou, X; Wei, S; Zhang, L | 1 |
| Gui, D; Guo, Y; Jiang, Q; Wang, N | 1 |
| Li, H; Wang, X; Wang, Z | 1 |
| Feng, Y; Gao, Y; Hu, J; Lin, S; Sun, F; Wu, G; Yang, J | 1 |
| Bardyn, M; Cortés-Salazar, F; Delobel, J; Girault, HH; Lesch, A; Lion, N; Maye, S; Prudent, M; Tacchini, P; Tissot, JD | 1 |
| Anastasiadi, AT; Antonelou, MH; Avgeropoulos, A; Georgatzakou, HT; Karadimas, DG; Kazepidou, E; Kriebardis, AG; Lekka, M; Moschovas, D; Papassideri, IS; Stamoulis, KE; Tzounakas, VL; Velentzas, AD; Zafeiropoulos, NE | 1 |
| Chen, Q; Jin, L; Li, J; Liu, J; Wang, T; Wang, W; Yu, H; Zhang, Y | 1 |
| Bazin, D; Daudon, M; Jungers, P; Williams, JC | 1 |
| Begum, J; Kumar, D; Kumar, P; Lingaraju, MC; Mathesh, K; Sharma, A; Singh, TU; Thakur, R | 1 |
| Gan, T; Liu, Y; Shi, Z; Sun, J; Wang, Z; Zheng, D | 1 |
| Chien, HC; Fenner, KS; Giacomini, KM; Gupta, A; Prasad, B; Stahl, SH; Stecula, A; Unadkat, JD; Wang, L; Yee, SW; Zou, L | 1 |
| Li, R; Liang, YN; Song, Y; Yang, H | 1 |
| Dong, F; He, P; He, S; Jia, L; Liu, K; Zhang, X | 1 |
| Li, Y; Liu, H; Luo, P; Zhang, D | 1 |
| Li, X; Liang, D; Liang, S; Lv, Y; Xu, F; Zeng, C; Zhu, X | 1 |
| Komori, H; Morokado, F; Nakanishi, T; Nishizawa, K; Tamai, I; Yoda, N | 1 |
| Eräranta, A; Kööbi, P; Lakkisto, P; Mustonen, J; Niemelä, O; Pörsti, I; Tikkanen, I; Törmänen, S | 1 |
| Botou, M; Charalambous, V; Flemetakis, E; Frillingos, S; Lazou, P; Mikros, E; Papakostas, K; Yalelis, V; Zantza, I | 1 |
| Cao, LH; Kang, L; Liu, HJ; Miao, JX; Miao, MS; Miao, YY; Song, YG; Xiang, LL | 1 |
| Bao, R; Chen, Q; Liu, L; Liu, M; Wang, D; Wang, T; Wen, S; Yu, H; Zhang, Y | 1 |
| Chen, A; Govindhan, M; Liu, Z; Mao, B; Qian, L | 1 |
| Chen, S; Fan, G; Wang, P; Wang, Z; Wen, Y; Xu, L; Zhang, K; Zhuo, Z | 1 |
| Li, X; Tan, Z; Wu, Y; Zhu, J | 1 |
| Chen, D; Chen, G; Lin, J; Lin, Y; Liu, A; Luo, T; Ouyang, D; Pan, H; Qin, M; Zhou, X | 1 |
| Abramov, G; Pozdnyakova, Y; Shakeev, K; Shestakov, D; Tankibaeva, N; Tusupbekova, M | 1 |
| Amatjan, M; He, P; Jiang, Q; Li, N; Mai, X; Shao, X; Xie, H; Zhang, B | 1 |
| Chen, N; Li, H; Meng, J; Yang, B; Yang, YF | 1 |
| Chudasama, P; Patel, P; Patel, S; Raval, M; Soni, S | 1 |
| Angeloni, C; Borghi, C; Cicero, AFG; Di Micoli, V; Fogacci, F; Giovannini, M | 1 |
7 review(s) available for adenine and uric acid
| Article | Year |
|---|---|
Membrane transport of purine and pyrimidine bases and nucleosides in animal cells.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine; Animals; Binding Sites; Binding, Competitive; Biological Transport, Active; Blood; Blood Cells; Cell Division; Cell Line; Cell Membrane; Cyclic AMP; Hypoxanthines; Intestinal Mucosa; Kinetics; Lipids; Nucleosides; Phosphorus; Purines; Pyrimidines; Structure-Activity Relationship; Temperature; Thymidine; Uric Acid; Uridine | 1975 |
2,8-Dihydroxyadeninuria--or when is a uric acid stone not a uric acid stone?
Topics: Acute Kidney Injury; Adenine; Adenine Phosphoribosyltransferase; Allopurinol; Diagnosis, Differential; Diet; Heterozygote; Homozygote; Humans; Pentosyltransferases; Purine-Pyrimidine Metabolism, Inborn Errors; Uric Acid; Urinary Calculi | 1979 |
Phosphoribosylpyrophosphate in man: biochemical and clinical significance.
Topics: Adenine; Adrenocorticotropic Hormone; Allopurinol; Animals; Glycogen; Gout; Humans; Lesch-Nyhan Syndrome; Methylene Blue; Orotic Acid; Pentosephosphates; Phosphoric Acids; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Ribose; Thiadiazoles; Thyrotropin; Transferases; Urate Oxidase; Uric Acid | 1971 |
Genetic aspects of gout.
Topics: Adenine; Allopurinol; Carbon Radioisotopes; Erythrocytes; Fibroblasts; Glucosephosphate Dehydrogenase; Glutamine; Glutathione Reductase; Gout; Guanine; Humans; Hypoxanthines; Lesch-Nyhan Syndrome; Liver; Metabolic Diseases; Molecular Weight; Orotic Acid; Pentosyltransferases; Purines; Uric Acid; Xanthine Oxidase | 1974 |
Hypoxanthine-guanine phosphoribosyltransferase deficiency in gout.
Topics: Adenine; Adolescent; Adult; Allopurinol; Azathioprine; Child; Child, Preschool; Female; Gout; Humans; Hypoxanthines; Male; Middle Aged; Pedigree; Pharmacogenetics; Phenotype; Purines; Transferases; Uric Acid | 1969 |
Biosynthesis of uric acid in the tunicate, Molgula manhattensis, with a general scheme for the function of stored purines in animals.
Topics: Adenine; Allopurinol; Animals; Carbon Isotopes; Carbonates; Chordata, Nonvertebrate; Formates; Glycine; Hypoxanthines; Purines; Serine; Tritium; Uric Acid; Xanthine Oxidase | 1970 |
Purine Metabolism Dysfunctions: Experimental Methods of Detection and Diagnostic Potential.
Topics: Adenine; Animals; Guanine; Humans; Mammals; Purines; Uric Acid; Xanthine Dehydrogenase | 2023 |
1 trial(s) available for adenine and uric acid
| Article | Year |
|---|---|
Metabolic and anthropometric changes one year after switching from didanosine/stavudine to tenofovir in HIV-infected patients.
Topics: Adenine; Adult; Aged; Anti-HIV Agents; Body Weight; CD4 Lymphocyte Count; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Creatinine; Didanosine; Female; Glomerular Filtration Rate; Glycated Hemoglobin; Hemoglobins; HIV Infections; Humans; Lactic Acid; Male; Middle Aged; Organophosphonates; Phosphates; Skinfold Thickness; Stavudine; Tenofovir; Treatment Outcome; Triglycerides; Uric Acid; Viral Load | 2007 |
178 other study(ies) available for adenine and uric acid
| Article | Year |
|---|---|
Inhibition of CTP synthase from Escherichia coli by xanthines and uric acids.
Topics: Carbon-Nitrogen Ligases; Enzyme Inhibitors; Escherichia coli; Kinetics; Methylation; Structure-Activity Relationship; Uric Acid; Xanthines | 2010 |
Vasopressin-stimulated movement of drugs and uric acid across the toad urinary bladder.
Topics: Adenine; Animals; Anti-Bacterial Agents; Anura; Butanols; Cell Membrane Permeability; Cyclic AMP; Cyclohexanones; Female; Fluorouracil; Glutethimide; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Phloretin; Stimulation, Chemical; Uric Acid; Urinary Bladder; Vasopressins | 1976 |
Role of purine base excretion in regulation of purine pools.
Topics: Adenine; Hypoxanthines; Inosine; Neurospora; Neurospora crassa; Purines; Uric Acid; Xanthines | 1979 |
Mechanism of inhibition of organic acid transport in rabbit renal cortex by cyclic AMP.
Topics: Adenine; Animals; Biological Transport, Active; Cyclic AMP; Cyclic GMP; Iodohippuric Acid; Isoproterenol; Kidney Cortex; Kinetics; Parathyroid Hormone; Propranolol; Rabbits; Theophylline; Uric Acid | 1976 |
Purine excretion by mouse peritoneal macrophages lacking adenosine deaminase activity.
Topics: Adenine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Deoxyadenosines; Female; Macrophages; Mice; Nucleoside Deaminases; Purines; Pyrimidines; Uric Acid | 1979 |
Overproduction of uric acid in hypoxanthine-guanine phosphoribosyltransferase deficiency. Contribution by impaired purine salvage.
Topics: Adenine; Adolescent; Adult; Aged; Carbon Radioisotopes; Child; Child, Preschool; Fructose; Humans; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Inosine; Lesch-Nyhan Syndrome; Middle Aged; Purines; Uric Acid | 1979 |
Urate-binding proteins in plasma studied by affinity chromatography.
Topics: Adenine; Carrier Proteins; Chromatography, Affinity; Guanine; Humans; Indicators and Reagents; Uric Acid; Xanthines | 1979 |
The influence of purines on plasma lecithin: cholesterole acyltransferase activity in the rat.
Topics: Acyltransferases; Adenine; Animals; Guanine; Hypoxanthines; Microsomes, Liver; Purines; Rats; Sterol O-Acyltransferase; Uric Acid; Xanthines | 1978 |
Adenine phosphoribosyltransferase deficiency presenting with supposed 'uric acid' stones: pitfalls of diagnosis.
Topics: Adenine; Adenine Phosphoribosyltransferase; Diagnosis, Differential; Female; Humans; Infant; Kidney Calculi; Pentosyltransferases; Ureteral Calculi; Uric Acid; Urinary Calculi | 1978 |
Species and tissue differences in the catabolism of S-adenosyl-L-homocysteine: a quantitative, chromatographic study.
Topics: Adenine; Animals; Brain; Chromatography, High Pressure Liquid; Homocysteine; Hydrolases; Hypoxanthines; Inosine; Kidney; Liver; Male; Mice; Rats; S-Adenosylhomocysteine; Species Specificity; Uric Acid; Xanthines | 1977 |
Complete deficiency of adenine phosphoribosyltransferase: report of a family.
Topics: Adenine; Adenine Phosphoribosyltransferase; Erythrocytes; Genes, Recessive; Humans; Hypoxanthine Phosphoribosyltransferase; Pedigree; Pentosyltransferases; Uric Acid; Urinary Calculi | 1977 |
Metabolism of intravenous adenine in the pig.
Topics: Adenine; Administration, Oral; Allantoin; Allopurinol; Animals; Hypoxanthines; Injections, Intravenous; Species Specificity; Swine; Uric Acid; Xanthines | 1977 |
Purine excretion in complete adenine phosphoribosyltransferase deficiency: effect of diet and allopurinol therapy.
Topics: Adenine; Adenine Phosphoribosyltransferase; Allopurinol; Child, Preschool; Diet; Humans; Male; Orotic Acid; Pentosyltransferases; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Uric Acid | 1977 |
Complete deficiency of adenine phosphoribosyltransferase. Report of a family.
Topics: Adenine; Adenine Phosphoribosyltransferase; Allopurinol; Child; Child, Preschool; Crystallization; Female; Heterozygote; Homozygote; Humans; Infant; Male; Pedigree; Pentosyltransferases; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Uric Acid; Urinary Calculi | 1977 |
The effects of added purines on urate and purine synthesis de novo by isolated chick liver, kidney and lymphoid cells.
Topics: Adenine; Adenosine Monophosphate; Animals; Chickens; Formates; Glycine; Guanine; Guanine Nucleotides; In Vitro Techniques; Inosine; Inosine Monophosphate; Kidney; Liver; Lymphoid Tissue; Phosphoribosyl Pyrophosphate; Purines; Stimulation, Chemical; Uric Acid | 1976 |
N-methylation of purines and pyrimidines.
Topics: Adenine; Chemical Phenomena; Chemistry; Chromatography, Gas; Dimethyl Sulfoxide; Mass Spectrometry; Methods; Methylation; Purines; Pyrimidines; Thymine; Uric Acid; Xanthines | 1975 |
[Proceedings: New case of Lesch-Nyhan syndrome. Attempt at treatment using adenine].
Topics: Adenine; Allopurinol; Humans; Infant; Lesch-Nyhan Syndrome; Male; Uric Acid | 1975 |
Stacking interactions of nucleobases: NMR-investigations. II. Self-association of purine-and pyrimidine-derivatives.
Topics: Adenine; Adenosine; Caffeine; Chemical Phenomena; Chemistry; Cytosine; Deuterium; Hypoxanthines; Magnetic Resonance Spectroscopy; Polymers; Purines; Pyrimidines; Thermodynamics; Uracil; Uric Acid; Water | 1975 |
Association of sexual hormones with nucleobases in water: NMR-investigations.
Topics: Adenine; Adenosine; Caffeine; Chemical Phenomena; Chemistry; Cytosine; Deuterium; Estradiol; Hypoxanthines; Magnetic Resonance Spectroscopy; Purines; Pyrimidines; Testosterone; Thermodynamics; Uracil; Uric Acid; Water | 1975 |
2,8-Dihydroxyadenine urolithiasis.
Topics: Adenine; Adenine Phosphoribosyltransferase; Chromatography, Thin Layer; Humans; Luminescent Measurements; Uric Acid; Urinary Calculi | 1992 |
2,8-Dihydroxyadenine urolithiasis.
Topics: Adenine; Child; Diagnosis, Differential; Humans; Uric Acid; Urinary Calculi | 1992 |
Changes in serum and urinary uric acid levels in normal human subjects fed purine-rich foods containing different amounts of adenine and hypoxanthine.
Topics: Adenine; Adult; Diet; Food Analysis; Glycine max; Humans; Hypoxanthine; Hypoxanthines; Liver; Male; Middle Aged; Purines; Uric Acid | 1992 |
Absorption and metabolism of purines by the lower intestine of the chicken.
Topics: Adenine; Animals; Chickens; Guanine; Hypoxanthine; Hypoxanthines; Intestinal Absorption; Intestinal Mucosa; Intestines; Male; Purines; Uric Acid; Xanthine; Xanthines | 1991 |
Purine metabolites and pyrimidine bases in cerebrospinal fluid of children with simple febrile seizures.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Child, Preschool; Cytosine; Female; Guanine; Guanosine; Humans; Hypoxanthine; Hypoxanthines; Infant; Inosine; Inosine Monophosphate; Male; Purines; Pyrimidine Nucleosides; Seizures, Febrile; Thymine; Uracil; Uric Acid; Xanthine; Xanthines | 1991 |
Enhanced adenine nucleotide degradation in chronic obstructive pulmonary disease: the effect of oxygen therapy.
Topics: Adenine; Adenine Nucleotides; Aged; Female; Humans; Hypoxanthines; Lung Diseases, Obstructive; Male; Middle Aged; Oxygen Inhalation Therapy; Uric Acid; Xanthines | 1989 |
Purine enzyme defects as a cause of acute renal failure in childhood.
Topics: Acute Kidney Injury; Adenine; Adenine Phosphoribosyltransferase; Adolescent; Child; Child, Preschool; Creatinine; Female; Humans; Hypoxanthine Phosphoribosyltransferase; Infant; Male; Purine-Pyrimidine Metabolism, Inborn Errors; Uric Acid | 1989 |
Differentiation of uric acid from dihydroxyadenine stones.
Topics: Adenine; Adenine Phosphoribosyltransferase; Humans; Luminescent Measurements; Uric Acid; Urinary Calculi | 1987 |
Response of the wild type and low xanthine dehydrogenase strains of Drosophila melanogaster to adenine resistance selection.
Topics: Adenine; Animals; Drosophila melanogaster; Drug Resistance; Female; Ketone Oxidoreductases; Male; Mutation; Sex Characteristics; Uric Acid; Xanthine Dehydrogenase | 1987 |
[Are urate calculi always urates?].
Topics: Adenine; Adenine Phosphoribosyltransferase; Female; Humans; Male; Middle Aged; Pedigree; Pentosyltransferases; Uric Acid; Urinary Calculi | 1988 |
Differences in uricogenic effects of dietary purine bases, nucleosides and nucleotides in rats.
Topics: Adenine; Allantoin; Animals; Creatinine; Diet; Kidney Calculi; Kidney Tubules; Male; Microscopy, Electron; Purine Nucleosides; Purine Nucleotides; Purines; Rats; Rats, Inbred Strains; Uric Acid | 1988 |
Liquid chromatography with multichannel ultraviolet detection used for studying disorders of purine metabolism.
Topics: Adenine; Allopurinol; Chromatography, High Pressure Liquid; Humans; Hypoxanthine; Hypoxanthines; Inosine; Oxypurinol; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Spectrophotometry, Ultraviolet; Uric Acid; Uridine; Xanthine; Xanthines | 1987 |
2,8-Dihydroxyadenine lithiasis.
Topics: Adenine; Adenine Phosphoribosyltransferase; Allopurinol; Diagnosis, Differential; Humans; Kidney Calculi; Uric Acid | 1986 |
Hereditary xanthinuria. Evidence for enhanced hypoxanthine salvage.
Topics: Adenine; Adenine Nucleotides; Adolescent; Adult; Female; Fructose; Guanosine; Humans; Hypoxanthine; Hypoxanthines; Male; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Uric Acid; Xanthine; Xanthine Oxidase; Xanthines | 1987 |
Identification of hypoxanthine transport and xanthine oxidase activity in brain capillaries.
Topics: Adenine; Allopurinol; Animals; Biological Transport; Blood-Brain Barrier; Brain; Brain Ischemia; Capillaries; Cerebral Cortex; Hypoxanthine; Hypoxanthines; Kinetics; Rats; Uric Acid; Xanthine; Xanthine Oxidase; Xanthines | 1985 |
Adenosine triphosphate degradation in specific disease.
Topics: Adenine; Adenosine Triphosphate; Biotransformation; Carnitine O-Palmitoyltransferase; Ethanol; Fructose; Glycogen Storage Disease Type I; Glycogen Storage Disease Type V; Gout; Humans; Hypoxia; Metabolic Diseases; Models, Biological; Muscular Diseases; Physical Exertion; Purinones; Uric Acid | 1985 |
Yeast species utilizing uric acid, adenine, n-alkylamines or diamines as sole source of carbon and energy.
Topics: Adenine; Alkylation; Amines; Candida; Cryptococcus; Culture Media; Diamines; Species Specificity; Trichosporon; Uric Acid; Yeasts | 1985 |
Adenine therapy in Lesch-Nyhan syndrome.
Topics: Adenine; Allopurinol; Child; Drug Therapy, Combination; Female; Humans; Hypoxanthine Phosphoribosyltransferase; Lesch-Nyhan Syndrome; Purines; Uric Acid | 1985 |
New amino acids, and heterocyclic compounds participating in the Stickland reaction of Clostridium sticklandii.
Topics: Adenine; Alcohol Oxidoreductases; Amino Acids; Anaerobiosis; Chromatography, Thin Layer; Clostridium; Electron Transport; Fluorescence; Fluorometry; Formates; Glucosephosphate Dehydrogenase; Glutamate Dehydrogenase; Glutamates; Heterocyclic Compounds; Histidine; L-Lactate Dehydrogenase; Methods; NAD; NADP; Oxidation-Reduction; Pyrimidinones; Uric Acid; Xanthines | 1973 |
Megaloblastic anaemia in the Lesch-Nyhan syndrome.
Topics: Adenine; Anemia, Macrocytic; Cerebral Palsy; Child; Humans; Intellectual Disability; Male; Movement Disorders; Self Mutilation; Uric Acid | 1968 |
Determination of urinary constituents in solutions by least-squares resolution of ultraviolet spectrums.
Topics: Acids; Adenine; Aminobenzoates; Ascorbic Acid; Benzoates; Cinnamates; Computers; Creatinine; Cytosine; Ergothioneine; Hippurates; Hypoxanthines; Indican; Niacinamide; ortho-Aminobenzoates; Spectrum Analysis; Statistics as Topic; Tryptophan; Ultraviolet Rays; Uric Acid; Urine; Xanthurenates | 1968 |
Activities of hypoxanthine-guanine phosphoribosyltransferase and adenine phosphoribosyltransferase in erythrocytes from patients with Down's syndrome.
Topics: Adenine; Child; Chromosomes, Human, 21-22 and Y; Down Syndrome; Erythrocytes; Guanine; Humans; Hypoxanthines; Pentosyltransferases; Uric Acid | 1972 |
Effect of purines on epinephrine-induced lipolysis in adipose tissue.
Topics: Adenine; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Caffeine; Enzymes; Epinephrine; Fatty Acids; Guanine; Hypoxanthines; In Vitro Techniques; Lipid Metabolism; Purines; Rats; Uric Acid; Xanthines | 1966 |
Effects of orotic acid on purine and lipoprotein metabolism in man.
Topics: Adenine; Administration, Oral; Carbon Isotopes; Cholesterol; Diphosphates; Erythrocytes; Glycine; Guanine; Humans; Kidney; Lipoproteins; Metabolic Clearance Rate; Nitrogen; Orotic Acid; Purines; Radioisotopes; Ribose; Transferases; Triglycerides; Uric Acid | 1970 |
Polymorphonuclear leukocyte motility in vitro. VI. Effect of purine and pyrimidine analogues: possible role of cyclic AMP.
Topics: Adenine; Caffeine; Cyclic AMP; Epinephrine; Guanine; Guanosine; Humans; Hypoxanthines; Imidazoles; Leukocytes; Movement; Purines; Pyrimidines; Reserpine; Structure-Activity Relationship; Theophylline; Thymine; Uracil; Uric Acid; Xanthines | 1972 |
Increased activity of adenine phosphoribosyltransferase in erythrocytes of normal newborn infants.
Topics: Adenine; Adult; Age Factors; Carbon Radioisotopes; Electrophoresis, Polyacrylamide Gel; Erythrocyte Aging; Erythrocytes; Guanine Nucleotides; Humans; Infant, Newborn; Inosine Nucleotides; Lesch-Nyhan Syndrome; Organophosphorus Compounds; Pentosephosphates; Pentosyltransferases; Phosphoric Acids; Sex Factors; Uric Acid | 1974 |
Increased PP-ribose-P synthetase activity: a genetic abnormality leading to excessive purine production and gout.
Topics: Adenine; Carbon Radioisotopes; Cellulose; Creatinine; Electrophoresis; Enzyme Activation; Erythrocytes; Female; Fibroblasts; Glycine; Gout; Guanine Nucleotides; Humans; Hypoxanthines; Male; Pedigree; Pentosephosphates; Pentosyltransferases; Phosphates; Phosphoric Acids; Phosphotransferases; Purines; Uric Acid | 1973 |
Observations of altered intracellular phosphoribosylpyrophosphate (PP-ribose-P) in human disease.
Topics: Adenine; Carbon Radioisotopes; Erythrocytes; Fibroblasts; Formates; Gout; Guanine Nucleotides; Heterozygote; Homozygote; Humans; Inosine Nucleotides; Methylene Blue; Orotic Acid; Pentosephosphates; Pentosyltransferases; Phosphoric Acids; Ribonucleotides; Uric Acid | 1974 |
Erythrocyte phosphoribosylpyrophosphate concentrations in heterozygotes for hypoxanthine-guanine phosphoribosyltransferase deficiency.
Topics: Adenine; Carbon Radioisotopes; Erythrocytes; Female; Heterozygote; Humans; Inosine Nucleotides; Lesch-Nyhan Syndrome; Male; Organophosphorus Compounds; Pentosephosphates; Pentosyltransferases; Phosphates; Phosphoric Acids; Uric Acid | 1974 |
Acid-soluble metabolites of adenine-2-14C-adenine-8-14C in 2,6-diaminopurine-sensitive and 2,6-diaminopurine-resistant L strain mouse cells.
Topics: Adenine; Adenine Nucleotides; Animals; Carbon Isotopes; Chromatography, Ion Exchange; Chromatography, Paper; Guanine; Guanine Nucleotides; L Cells; Mice; NAD; NADP; Nucleosides; Perchlorates; Purines; Urea; Uric Acid; Xanthines | 1968 |
Purine and pyrimidine absorption by the gut of the chiton, Cryptochiton stelleri.
Topics: Adenine; Aerobiosis; Anaerobiosis; Animals; Biological Transport, Active; Cytosine; Female; Guanine; Hypoxanthines; Intestinal Absorption; Male; Mollusca; Purines; Thymine; Uracil; Uric Acid | 1972 |
Effect of allopurinol (4-hydroxyprazolo(3,4-d)pyrimidine) on xanthine accumulation by milk xanthine oxidase in vitro.
Topics: Adenine; Allopurinol; Animals; Antimetabolites; Aza Compounds; Azaguanine; Hypoxanthines; In Vitro Techniques; Mercaptopurine; Milk; Oxidoreductases; Purines; Spectrophotometry; Uric Acid; Xanthine Oxidase; Xanthines | 1974 |
[Scury and purine catabolism].
Topics: Adenine; Allantoin; Animals; Ascorbic Acid Deficiency; Guanine; Guinea Pigs; Purines; Scurvy; Stimulation, Chemical; Urate Oxidase; Urea; Uric Acid; Xanthine Oxidase | 1974 |
Clinical and biochemical studies on treatment of Lesch-Nyhan syndrome.
Topics: Adenine; Allopurinol; Body Weight; Child, Preschool; Chlorpromazine; Creatinine; Exchange Transfusion, Whole Blood; Humans; Language Development; Lesch-Nyhan Syndrome; Male; Motor Skills; Movement Disorders; Pedigree; Pentosyltransferases; Phenothiazines; Tetrabenazine; Uric Acid | 1974 |
The Lesch-Nyhan syndrome: report of three cases.
Topics: Adenine; Adolescent; Adult; Allopurinol; Athetosis; Australia; Child; Humans; Hypoxanthines; Intellectual Disability; Lesch-Nyhan Syndrome; Male; Phosphotransferases; Purine-Pyrimidine Metabolism, Inborn Errors; Self Mutilation; Uric Acid; Xanthines | 1972 |
Inhibition of adenosine uptake by platelets.
Topics: Adenine; Adenosine; Blood Platelets; Buffers; Carbon Isotopes; Dipyridamole; Drug Synergism; Humans; Hypoxanthines; In Vitro Techniques; Inosine; Uric Acid | 1972 |
Variations in purine phosphoribosyl transferase enzymes during growth of fibroblast cell cultures.
Topics: Adenine; Adenosine Monophosphate; Carbon Isotopes; Cell Division; Cells, Cultured; Clinical Enzyme Tests; Erythrocytes; Fibroblasts; Hemolysis; Humans; Hypoxanthines; Infant; Inosine Nucleotides; Lesch-Nyhan Syndrome; Male; Pentosephosphates; Pentosyltransferases; Skin; Uric Acid | 1972 |
[Purine transport in Pichia guilliermondii yeasts].
Topics: Adenine; Azides; Biological Transport; Cells, Cultured; Culture Media; Cycloheximide; Guanine; Guanosine; Hypoxanthines; Kinetics; Membrane Transport Proteins; Purines; Sodium; Spectrophotometry; Uric Acid; Xanthines; Yeasts | 1972 |
Metabolism of purines in cultured normal and HPRT-deficient human fibroblasts.
Topics: Adenine; Adenosine Monophosphate; Age Factors; Carbon Isotopes; Cells, Cultured; Chromatography, Paper; Dialysis; Electrophoresis; Erythrocytes; Fibroblasts; Humans; Hypoxanthines; Infant; Metabolism, Inborn Errors; Nucleosides; Pentosyltransferases; Proteins; Purine Nucleotides; Purines; Skin; Uric Acid | 1973 |
The Lesch-Nyhan syndrome. Metabolic studies during administration of adenine.
Topics: Adenine; Carbon Isotopes; Glycine; Humans; Hypoxanthines; Infant; Lesch-Nyhan Syndrome; Male; Pentosyltransferases; Purines; Uric Acid; Xanthines | 1973 |
An atypical case of hypoxanthine-guanine phosphoribosyltransferase deficiency (Lesch-Nyhan syndrome). II. Genetic studies.
Topics: Adenine; Autoradiography; Blood Group Antigens; Carbon Radioisotopes; Erythrocytes; Female; Fibroblasts; Genotype; Hair; Humans; Hypoxanthines; Lesch-Nyhan Syndrome; Lymphocytes; Male; Pedigree; Pentosyltransferases; Tritium; Uric Acid | 1973 |
Adenine phosphoribosyltransferase deficiency in man. Report of a second family.
Topics: Adenine; Adenosine Triphosphate; Cells, Cultured; Chromosome Aberrations; Chromosome Disorders; Erythrocytes; Female; Half-Life; Heterozygote; Hot Temperature; Humans; Leukocytes; Male; Metabolism, Inborn Errors; Middle Aged; Pedigree; Pentosyltransferases; Purine Nucleotides; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Uric Acid | 1973 |
Erythrocyte PRPP concentrations in heterozygotes for HGPRTase deficiency.
Topics: Adenine; Erythrocytes; Female; Glycerophosphates; Guanine Nucleotides; Heterozygote; Humans; Hypoxanthines; Inosine Nucleotides; Lesch-Nyhan Syndrome; Male; Pedigree; Pentosephosphates; Pentosyltransferases; Uric Acid | 1973 |
Adenine phosphoribosyltransferase deficiency: report of a second family.
Topics: Adenine; Adenosine Triphosphate; Creatinine; Drug Stability; Erythrocytes; Female; Fibroblasts; Fructose; Hot Temperature; Humans; Leukocytes; Male; Middle Aged; Pedigree; Pentosephosphates; Pentosyltransferases; Purine-Pyrimidine Metabolism, Inborn Errors; Time Factors; Uric Acid | 1973 |
Adenine phosphoribosyltransferase deficiency in a female with gout.
Topics: Adenine; Adult; Carbon Radioisotopes; Creatinine; Erythrocytes; Female; Glycine; Gout; Humans; Pentosephosphates; Pentosyltransferases; Time Factors; Uric Acid | 1973 |
Gout with adenine phosphoribosyl transferase deficiency.
Topics: Adenine; Allopurinol; Carbon Radioisotopes; Erythrocytes; Female; Glycine; Gout; Humans; Male; Pedigree; Pentosephosphates; Pentosyltransferases; Purines; Sulfhydryl Compounds; Uric Acid | 1973 |
Utilization of nitrogen from selected purines and pyrimidines and from urea by the young chick.
Topics: Adenine; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Body Water; Body Weight; Chickens; Chlortetracycline; Deficiency Diseases; Diet; Glutamates; Male; Nitrogen; Proteins; Purines; Uracil; Urea; Uric Acid; Xanthines | 1974 |
The uptake of glycine-14C into the adenine and guanine of DNA and insoluble RNA of human leucocytes.
Topics: Adenine; Autoanalysis; Carbon Radioisotopes; Chromatography, Paper; DNA; Female; Glycine; Gout; Guanine; Humans; Kidney Failure, Chronic; Leukocytes; Male; RNA; Solubility; Uric Acid | 1974 |
Allopurinol and thiopurinol: effect in vivo on urinary oxypurine excretion and rate of synthesis of their ribonucleotides in different enzymatic deficiencies.
Topics: Adenine; Allopurinol; Erythrocytes; Female; Gout; Guanine; Humans; Hypoxanthines; Lesch-Nyhan Syndrome; Male; Pentosephosphates; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Pyrazoles; Pyrimidines; Sulfhydryl Compounds; Time Factors; Uric Acid; Xanthines | 1974 |
Acute renal failure during adenine therapy in Lesch-Nyhan syndrome.
Topics: Acute Kidney Injury; Adenine; Body Weight; Child, Preschool; Creatinine; Erythrocytes; Humans; Hydrogen-Ion Concentration; Lesch-Nyhan Syndrome; Male; Pentosephosphates; Time Factors; Urea; Uric Acid | 1974 |
Gout with adenine phosphoribosyl transferase deficiency.
Topics: Adenine; Adolescent; Adult; Aged; Allopurinol; Carbon Radioisotopes; Child; Child, Preschool; Chromosome Aberrations; Chromosome Disorders; Female; Gout; Humans; Karyotyping; Male; Middle Aged; Pedigree; Pentosyltransferases; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Ribonucleosides; Uric Acid; Xanthines | 1974 |
A screening test for urinary purines and pyrimidines and related compounds using auxotrophic mutants of Escherichia coli K12.
Topics: Adenine; Alanine; Aspartic Acid; Biological Assay; Carbamates; Child; Chromatography, Paper; Cytosine; Escherichia coli; Glycosides; Humans; Imidazoles; Inosine; Mutation; Orotic Acid; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Purinones; Pyrimidines; Ribose; Thymine; Uracil; Uric Acid | 1970 |
Azaguanine-resistance as a manifestation of a new form of metabolic overproduction of uric acid.
Topics: Adenine; Adolescent; Aminopterin; Azaguanine; Blood Urea Nitrogen; Carbon Isotopes; Cell Line; Creatinine; Drug Resistance; Electrophoresis, Starch Gel; Erythrocytes; Fibroblasts; Gout; Guanine; Humans; Hypoxanthines; Lesch-Nyhan Syndrome; Male; Mercaptopurine; Pentosyltransferases; Purines; Uric Acid | 1972 |
Studies on the mechanism of fructose-induced hyperuricemia in man.
Topics: Adenine; Adenosine Triphosphate; Aged; Allopurinol; Erythrocytes; Fasting; Fructose; Glucose; Gout; Guanine; Humans; Hypoxanthines; Lactates; Male; Metabolic Clearance Rate; Middle Aged; Pentosyltransferases; Phosphates; Purine Nucleotides; Purines; Ribose; Uric Acid | 1972 |
Alterations in the activity of hypoxanthine and adenine phosphoribosyltransferase in patients with hyperuricaemia and gout.
Topics: Adenine; Adult; Erythrocytes; Gout; Humans; Hypoxanthines; Lesch-Nyhan Syndrome; Pentosyltransferases; Purine-Pyrimidine Metabolism, Inborn Errors; Uric Acid | 1971 |
[On the aminomethylation of xanthine, hypoxanthine, adenine, guanine and uric acid].
Topics: Adenine; Amines; Chemical Phenomena; Chemistry; Methylation; Purinones; Uric Acid | 1967 |
Cell population density and phenotypic expression of tissue culture fibroblasts from heterozygotes of Lesch-Nyhan's disease (inosinate pyrophosphorylase deficiency).
Topics: Adenine; Autoradiography; Cell Line; Culture Techniques; Female; Fibroblasts; Heterozygote; Humans; Hypoxanthines; Intellectual Disability; Lymphocytes; Male; Nucleosides; Nucleotidyltransferases; Phenotype; Purines; Self Mutilation; Sex Chromosome Aberrations; Skin; Time Factors; Tritium; Uric Acid | 1969 |
Specificity of adenosine uptake into the heart and inhibition by dipyridamole.
Topics: Adenine; Animals; Carbon Isotopes; Dipyridamole; Guinea Pigs; Hypoxanthines; Lipids; Myocardium; Nucleosides; Ribose; Solubility; Uric Acid | 1970 |
The influence of adenine on the clinical features and purine metabolism in the Lesch-Nyhan syndrome.
Topics: Adenine; Allopurinol; Athetosis; Bone Marrow; Carbon Isotopes; Child; Child, Preschool; Chorea; Compulsive Behavior; Diet Therapy; Erythrocytes; Folic Acid; Glycine; Humans; Intellectual Disability; Male; Metabolism, Inborn Errors; Movement Disorders; Purines; Self Mutilation; Transferases; Uric Acid; Vitamin B 12 | 1970 |
[Enzymopathic gout. Dyspurinia due to hypoxanthine-guanine-phosphoribosyl-transferase deficiency. Occurrence and clinical characteristics of enzyme repression].
Topics: Adenine; Adult; Age Factors; Allopurinol; Enzyme Repression; Female; Gout; Guanine; Humans; Hypoxanthines; Kidney Calculi; Kidney Diseases; Male; Pedigree; Transferases; Uric Acid; Xanthines | 1970 |
Lesch-Nyhan syndrome: preventive control by prenatal diagnosis.
Topics: Adenine; Amniotic Fluid; Athetosis; Autoradiography; Basal Ganglia; Carbon Isotopes; Cerebellum; Cerebral Cortex; Chorea; Compulsive Behavior; Female; Fetal Diseases; Fibroblasts; Humans; Hypoxanthines; In Vitro Techniques; Intellectual Disability; Male; Pregnancy; Purine-Pyrimidine Metabolism, Inborn Errors; Self Mutilation; Sex Chromosomes; Skin; Testis; Transferases; Tritium; Uric Acid | 1970 |
Diagnosis of Lesch-Nyhan syndrome by direct study of skin specimens.
Topics: Adenine; Adolescent; Adult; Aged; Child; Clinical Enzyme Tests; Erythrocytes; Female; Fibroblasts; Guanine; Heterozygote; Humans; Hypoxanthines; Intellectual Disability; Male; Metabolism, Inborn Errors; Middle Aged; Movement Disorders; Self Mutilation; Skin; Transferases; Tritium; Uric Acid | 1970 |
Effect of dietary purine restriction, allupurinol, and oxipurinol on urinary excretion of ultraviolet-absorbing compounds.
Topics: Adenine; Allopurinol; Chromatography, Ion Exchange; Diet; Humans; Hypoxanthines; Orotic Acid; Purines; Pyrimidines; Spectrophotometry; Ultraviolet Rays; Uric Acid; Uridine; Xanthine Oxidase | 1970 |
[About an atypical catabolism of purines during the epidermal keratinization].
Topics: Adenine; Allantoin; Animals; Carbon Isotopes; Chromatography; Chromatography, Paper; Guanine; Guinea Pigs; Humans; Hypoxanthines; Keratins; Mice; Purines; Skin; Urea; Uric Acid; Xanthines | 1970 |
A new assay method for hypoxanthine-guanine phosphoribosyltransferase.
Topics: Adenine; Adenine Nucleotides; Athetosis; Carbon Isotopes; Chorea; Chromatography; Compulsive Behavior; Erythrocytes; Gout; Guanine; Guanine Nucleotides; Humans; Hypoxanthines; Intellectual Disability; Proteins; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Self Mutilation; Transferases; Uric Acid | 1970 |
[Effect of colchicine and allopurinol on uricogenesis. II. Effect of administration to chicks and mice].
Topics: Adenine; Allopurinol; Animals; Chickens; Colchicine; Colorimetry; Dialysis; Hypoxanthines; Injections, Intraperitoneal; Kidney; Liver; Mice; Nucleosides; Spectrophotometry; Uric Acid; Xanthine Oxidase | 1970 |
Phosphoribosyl transferase activity in normal subjects, gout patients, and children with mental retardation.
Topics: Adenine; Adolescent; Adult; Child; Child, Preschool; Creatinine; Erythrocytes; Female; Gout; Guanine; Humans; Hypoxanthines; Intellectual Disability; Male; Metabolism, Inborn Errors; Radiochemistry; Transferases; Uric Acid | 1971 |
[On the formation of uric acid by hepatic xanthinedehydrogenase].
Topics: Adenine; Animals; Chickens; Liver; Uric Acid; Xanthine Oxidase | 1967 |
An enzymatic basis for variation in response to allopurinol. Hypoxanthine-guanine phosphoribosyltransferase deficiency.
Topics: Adenine; Adolescent; Adult; Aged; Allopurinol; Child; Creatinine; Glucosyltransferases; Gout; Guanine; Humans; Hypoxanthines; Male; Metabolism, Inborn Errors; Middle Aged; Purines; Uric Acid; Xanthines | 1968 |
Purine metabolism in the chick embryo; effects of uricogenesis and xanthine oxidase inhibition.
Topics: Adenine; Amines; Animals; Carbon Isotopes; Chick Embryo; Formates; Glycine; Guanine; Nucleic Acids; Nucleotides; Purines; Pyrazoles; Pyrimidines; Thiazoles; Uric Acid; Xanthine Oxidase | 1968 |
Comparative electrophoresis of cytidines, adenines, uracils and guanines.
Topics: Adenine; Electrophoresis; Guanine; Hydrogen-Ion Concentration; Nucleosides; Uracil; Uric Acid | 1968 |
Ultraviolet microscopy of purines and amino acids in the vacuole of Candida albicans.
Topics: Adenine; Amino Acids; Candida; Culture Media; Cytoplasm; Guanine; Microscopy; Purines; Pyrimidines; Spectrophotometry; Tyrosine; Ultraviolet Rays; Uric Acid; Xanthines | 1968 |
Secretion of purines by the small intestine: general characteristics.
Topics: Adenine; Allopurinol; Animals; Biological Transport; Caffeine; Carbon Isotopes; Chromatography, Paper; Cricetinae; Female; Hypoxanthines; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Methods; Nucleotides; Purines; Pyrimidines; Tritium; Uric Acid; Xanthine Oxidase | 1968 |
[The effect of iron on the purine metabolism and the formation of riboflavin of Candida guiliermondii (Cast.) Lang. et G].
Topics: Adenine; Candida; Carbon Isotopes; Glycine; Guanine; Hypoxanthines; Iron; Proteins; Purines; Riboflavin; RNA; Uric Acid; Xanthines | 1968 |
Congenital hyperuricemia. An inborn error of purine metabolism associated with psychomotor retardation, athetosis, and self-mutilation.
Topics: Adenine; Allopurinol; Athetosis; Child, Preschool; Diet Therapy; Genes, Recessive; Humans; Male; Metabolism, Inborn Errors; Nucleotides; Psychomotor Disorders; Purines; Self Mutilation; Sex Chromosomes; Transferases; Uric Acid | 1969 |
Purines: active transport by isolated choroid plexus.
Topics: Adenine; Allopurinol; Animals; Biological Transport, Active; Blood-Brain Barrier; Choroid Plexus; Female; Guanine; Hypoxanthines; In Vitro Techniques; Kinetics; Purines; Rabbits; Uracil; Uric Acid; Xanthines | 1969 |
Glycine-C-14 incorporation into nucleic acid purine by leucocytes obtained from normal and gouty subjects.
Topics: Adenine; Carbon Isotopes; Cyanides; Depression, Chemical; DNA; Female; Glycine; Gout; Guanine; Humans; Hypoxanthines; In Vitro Techniques; Iodoacetates; Leukocytes; Male; Purines; RNA; Uric Acid | 1969 |
A new disorder of purine metabolism with behavioral manifestations.
Topics: Adenine; Allopurinol; Autistic Disorder; Carbon Isotopes; Child Behavior Disorders; Child, Preschool; Erythrocytes; Glucosyltransferases; Glycine; Gout; Guanine; Humans; Hypoxanthines; Intellectual Disability; Male; Mutism; Nucleotides; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Uric Acid; Xanthenes | 1969 |
Degradation of xanthine by Penicillium chrysogenum.
Topics: Adenine; Allantoin; Amidohydrolases; Hypoxanthines; Penicillium; Urate Oxidase; Ureohydrolases; Uric Acid; Xanthine Oxidase; Xanthines | 1969 |
Hyperuricaemia: some biochemical aspects.
Topics: Adenine; Carbon Isotopes; Glycine; Humans; In Vitro Techniques; Intellectual Disability; Metabolic Diseases; Nitrogen; Nucleoproteins; Purines; Radioisotopes; Self Mutilation; Uric Acid | 1969 |
[Thin-layer chromatographic separation of some purine derivatives, including uric acid].
Topics: Adenine; Caffeine; Chromatography, Thin Layer; Guanine; Hypoxanthines; Purines; Theobromine; Theophylline; Uric Acid; Xanthines | 1966 |
[On the role of xanthine in riboflavine biosynthesis by the yeast Candida guilliermondii].
Topics: Adenine; Candida; Guanine; Nucleotides; Purines; Riboflavin; Uric Acid; Xanthines | 1966 |
Identification of a specific mode of oxidation in the radiolysis of the purine bases in oxygenated aqueous solution.
Topics: Adenine; Chromatography; Cobalt Isotopes; Spectrophotometry; Uric Acid; Xanthines | 1967 |
Metabolism of aminonucleoside-8-14C in the rat and guinea pig.
Topics: Adenine; Adrenal Glands; Allantoin; Amines; Animals; Biliary Tract; Carbon Dioxide; Carbon Isotopes; Feces; Guinea Pigs; Hypoxanthines; Intestine, Small; Kidney; Liver; Lung; Muscles; Myocardium; Nephrotic Syndrome; Nucleosides; Purines; Puromycin; Rats; Spleen; Stomach; Urea; Uric Acid; Xanthines | 1967 |
Degradation of perfused adenine compounds up to uric acid in isolated rat heart.
Topics: Adenine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Biotransformation; In Vitro Techniques; Male; Myocardium; Rats; Rats, Inbred Strains; Uric Acid | 1982 |
The effects of adenine derivatives on urate biosynthesis by isolated chicken liver cells [proceedings].
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Animals; Bucladesine; Chickens; Cyclic AMP; In Vitro Techniques; Liver; Uric Acid | 1980 |
Purine metabolism and urate biosynthesis in isolated chicken hepatocytes.
Topics: Adenine; Animals; Chickens; Glutamine; Guanine; In Vitro Techniques; Kinetics; Liver; Male; Phosphates; Purines; Uric Acid | 1984 |
[A problem on the uric acid value of rats for clinical evaluation].
Topics: Adenine; Allantoin; Animals; Humans; Male; Nucleic Acids; Purine-Pyrimidine Metabolism, Inborn Errors; Rats; Rats, Inbred Strains; Uric Acid | 1984 |
Adenine pool catabolism in the ischemic, the calcium-depleted ischemic, and the substrate free anoxic isolated rat heart: relationship to contracture development.
Topics: Adenine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Chromatography, High Pressure Liquid; Contracture; Coronary Disease; Energy Metabolism; Hypoxanthine; Hypoxanthines; Hypoxia; Inosine; Inosine Monophosphate; Male; Myocardium; Rats; Rats, Inbred Strains; Uric Acid | 1984 |
Trichosporon adeninovorans sp. nov., a yeast species utilizing adenine, xanthine, uric acid, putrescine and primary n-alkylamines as the sole source of carbon, nitrogen and energy.
Topics: Adenine; Amines; Energy Metabolism; Mitosporic Fungi; Putrescine; Soil Microbiology; Uric Acid; Xanthine; Xanthines | 1984 |
Use of high performance liquid chromatography to study absorption and metabolism of purines by rat jejunum in vitro.
Topics: Absorption; Adenine; Animals; Chromatography, High Pressure Liquid; Guanine; Hypoxanthines; Jejunum; Male; Nucleic Acids; Purines; Rats; Rats, Inbred Strains; Uric Acid; Xanthines | 1983 |
[Uric acid load test. Proof of its value using the sequential probability ratio test].
Topics: Adenine; Adult; Female; Gout; Guanine; Humans; Male; Probability; Uric Acid | 1982 |
2,8-dihydroxyadenine stone in children.
Topics: Adenine; Adenine Phosphoribosyltransferase; Child; Humans; Kidney Calculi; Male; Pentosyltransferases; Uric Acid; X-Ray Diffraction | 1982 |
Metabolic effects of dietary purine in rats.
Topics: Adenine; Allantoin; Animals; Blood Urea Nitrogen; Creatinine; Kidney; Male; Purines; Rats; Rats, Inbred Strains; Urea; Uric Acid | 1982 |
Dynamometric and biochemical observations in Duchenne patients receiving allopurinol.
Topics: Adenine; Allopurinol; Child; Creatine Kinase; Erythrocytes; Humans; Muscle Contraction; Muscular Dystrophies; Uric Acid | 1981 |
Uric acid crystal-induced nephropathy: evidence for a specific renal lesion in a gouty family.
Topics: Adenine; Adult; Animals; Child; Child, Preschool; Female; Gout; Humans; Kidney; Kidney Diseases; Swine; Uric Acid | 1981 |
Purine metabolism in Duchenne muscular dystrophy.
Topics: Adenine; Allopurinol; Biological Transport; Creatine Kinase; Erythrocyte Membrane; Female; Humans; Male; Muscles; Muscular Dystrophies; Purine Nucleotides; Uric Acid | 1980 |
Hypoxanthine salvage in man: its importance in urate overproduction in the Lesch-Nyhan syndrome.
Topics: Adenine; Fructose; Humans; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Kinetics; Lesch-Nyhan Syndrome; Uric Acid | 1980 |
Spectrum of 2,8-dihydroxyadenine urolithiasis in complete APRT deficiency.
Topics: Adenine; Adenine Phosphoribosyltransferase; Child; Child, Preschool; Creatinine; Female; Humans; Kidney; Kidney Calculi; Male; Pentosyltransferases; Purine-Pyrimidine Metabolism, Inborn Errors; Uric Acid | 1980 |
Purine metabolism in female patients with primary gout.
Topics: Adenine; Arthritis, Gouty; Creatinine; Female; Gout; Humans; Hypoxanthine; Hypoxanthines; Male; Purines; Radioisotope Dilution Technique; Reference Values; Sex Characteristics; Uric Acid; Xanthine; Xanthines | 1994 |
Concentration of purine compounds in the cerebrospinal fluid of infants suffering from sepsis, convulsions and hydrocephalus.
Topics: Adenine; Bacterial Infections; Chromatography, High Pressure Liquid; Humans; Hydrocephalus; Hypoxanthine; Hypoxanthines; Infant; Infant, Newborn; Inosine; Predictive Value of Tests; Purines; Seizures; Uric Acid; Xanthine; Xanthines | 1995 |
Validation and steady-state analysis of a power-law model of purine metabolism in man.
Topics: Adenine; Adenine Phosphoribosyltransferase; Guanine; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Kinetics; Models, Biological; Phosphoribosyl Pyrophosphate; Purines; Sensitivity and Specificity; Uric Acid; Xanthine; Xanthines | 1997 |
Kelley-Seegmiller syndrome due to a unique variant of hypoxanthine-guanine phosphoribosyltransferase: reduced affinity for 5-phosphoribosyl-1-pyrophosphate manifested only at low, physiological substrate concentrations.
Topics: Acute Kidney Injury; Adenine; Cells, Cultured; Child, Preschool; Culture Media, Conditioned; DNA Mutational Analysis; Fibroblasts; Gout; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Jews; Lymphocytes; Male; Nucleic Acids; Nucleotides; Phosphoribosyl Pyrophosphate; Purines; Syndrome; Uric Acid | 2000 |
Purine-induced alterations of dopamine metabolism in rat pheochromocytoma PC12 cells.
Topics: Adenine; Adenosine; Animals; Disease Models, Animal; Dopamine; Guanine; Guanosine; Hypoxanthine; Neostriatum; Neural Pathways; Neurons; Parkinson Disease; PC12 Cells; Purines; Rats; Substantia Nigra; Uric Acid; Xanthine | 2000 |
Method for the synthesis of uric acid derivatives.
Topics: 1-Propanol; Adenine; Alkylation; Ammonia; Guanine; Hydrocarbons, Iodinated; Mass Spectrometry; Methylation; Purines; Uric Acid | 2000 |
Substitution F569S converts UapA, a specific uric acid-xanthine transporter, into a broad specificity transporter for purine-related solutes.
Topics: Adenine; Alleles; Amino Acid Substitution; Aspergillus nidulans; Binding, Competitive; Biological Transport; Fungal Proteins; Genes, Fungal; Hypoxanthine; Kinetics; Membrane Transport Proteins; Purines; Solubility; Structure-Activity Relationship; Substrate Specificity; Suppression, Genetic; Uracil; Urea; Uric Acid; Xanthine | 2001 |
Adenoviruses encoding HPRT correct the biochemical abnormalities fully only in HPRT-deficient human cell lines: importance of species differences.
Topics: Adenine; Adenoviruses, Human; Animals; Cell Line; Cell Survival; Gene Transfer Techniques; Genetic Vectors; Guanosine Triphosphate; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Mice; Uric Acid; Uridine Diphosphate Glucose; Xanthine | 2000 |
[Hyperuricemia and gout--diagnosis].
Topics: Adenine; Adult; Diagnosis, Differential; Drug-Related Side Effects and Adverse Reactions; Female; Gout; Humans; Kidney Calculi; Kidney Diseases; Male; Recurrence; Uric Acid; Xanthine | 2002 |
Purine nucleotide catabolism in rat liver: labelling of uric acid and allantoin after administration of various labelled precursors.
Topics: Adenine; Allantoin; Animals; Formates; Glycine; Hypoxanthines; Isotope Labeling; Liver; Male; Purine Nucleotides; Rats; Uric Acid | 2002 |
[Substances derived from Crataegus. VIII. Adenosine, adenine, guanine, uric acid].
Topics: Adenine; Adenosine; Crataegus; Guanine; Plant Extracts; Plants; Uric Acid | 1955 |
Utilization of hypoxanthine, adenine and 4-amino-5-imidazole-carboxamide for uric acid synthesis in man.
Topics: Adenine; Amides; Humans; Hypoxanthine; Imidazoles; Male; Uric Acid; Xanthines | 1959 |
INTERACTION OF PURINES WITH THE PYRIMIDINE TRANSPORT PROCESS OF THE SMALL INTESTINE.
Topics: Adenine; Caffeine; Carbon Isotopes; Guanine; Intestine, Small; Intestines; Mercaptopurine; Pharmacology; Physiology; Purines; Pyrimidines; Rats; Research; Theobromine; Theophylline; Uracil; Uric Acid; Xanthines | 1963 |
CHEMICAL REACTIVITY OF THE NUCLEIC ACID BASES. I. ANTIOXIDATIVE ABILITY OF THE NUCLEIC ACIDS AND THEIR RELATED SUBSTANCES ON THE OXIDATION OF UNSATURATED FATTY ACIDS.
Topics: Adenine; Antioxidants; Catechols; Citrates; Copper; Diphosphates; Fats, Unsaturated; Fatty Acids, Unsaturated; Linoleic Acid; Lipid Metabolism; Nucleic Acids; Nucleosides; Orotic Acid; Oxidation-Reduction; Research; RNA; Uracil; Uric Acid; Vitamin E; Xanthines | 1963 |
PURINE METABOLISM OF UNICELLULAR ALGAE. I. CHROMATOGRAPHIC DETECTION OF SOME PURINES, PYRIMIDINES, AND IMIDAZOLES BY THEIR MERCURIC COMPLEXES.
Topics: Adenine; Alloxan; Chromatography; Creatine; Creatinine; Eukaryota; Guanine; Hydantoins; Hypoxanthines; Imidazoles; Mercury; Orotic Acid; Purines; Pyrimidines; Research; Ultraviolet Rays; Uric Acid; Xanthines | 1964 |
PURINE METABOLISM BY UNICELLULAR ALGAE. II. ADENINE, HYPOXANTHINE, AND XANTHINE DEGRADATION BY CHORELLA PYRENOIDOSA.
Topics: Adenine; Allantoin; Biochemical Phenomena; Chromatography; Eukaryota; Hypoxanthine; Hypoxanthines; Metabolism; Research; Spectrophotometry; Uric Acid; Xanthine; Xanthines | 1964 |
INTERMOLECULAR FORCES IN ASSOCIATION OF PURINES WITH POLYBENZENOID HYDROCARBONS.
Topics: Adenine; Benzopyrenes; Caffeine; Chemical Phenomena; Chemistry; Cytosine; Guanine; Hypoxanthines; London; Purines; Pyrimidines; Research; Thymine; Uracil; Uric Acid; Xanthines | 1965 |
THE STUDY OF PURINE UTILIZATION AND EXCRETION IN A XANTHINURIC MAN.
Topics: Adenine; Carbon Isotopes; Chromatography; Guanine; Humans; Hypoxanthines; Male; Metabolism, Inborn Errors; Nucleotides; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Spectrophotometry; Uric Acid; Urine; Xanthine Oxidase; Xanthines | 1965 |
Effect of inorganic phosphate and of drugs affecting renal uric acid excretion upon transport of uric acid through the human erythrocyte membrane.
Topics: Adenine; Biological Transport; Erythrocyte Membrane; Humans; Phosphates; Uric Acid; Xanthines | 1962 |
The AzgA purine transporter of Aspergillus nidulans. Characterization of a protein belonging to a new phylogenetic cluster.
Topics: Adenine; Alleles; Amino Acid Sequence; Aspergillus nidulans; Biological Transport; Blotting, Northern; Carrier Proteins; Cell Membrane; Cloning, Molecular; DNA; Escherichia coli; Gene Deletion; Hypoxanthine; Membrane Transport Proteins; Models, Genetic; Molecular Sequence Data; Multigene Family; Mutagenesis; Mutation; Nitrogen; Phenotype; Phylogeny; Plasmids; Protein Structure, Tertiary; Quaternary Ammonium Compounds; Sequence Homology, Amino Acid; Time Factors; Transcription, Genetic; Ultraviolet Rays; Uric Acid | 2004 |
2,8-Dihydroxyadenine renal stones in a 41-year-old man.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adult; Allopurinol; Antimetabolites; Humans; Kidney Calculi; Male; Uric Acid | 2004 |
Dietary fiber suppresses elevation of uric acid and urea nitrogen concentrations in serum of rats with renal dysfunction induced by dietary adenine.
Topics: Adenine; Animals; Blood Urea Nitrogen; Cellulose; Chitin; Chitosan; Creatinine; Diet; Dietary Fiber; Intestinal Absorption; Jejunum; Kidney; Kidney Diseases; Leukocyte Count; Male; Organ Size; Rats; Rats, Wistar; Uric Acid; Weight Gain | 2004 |
A common mutation in an organic anion transporter gene, SLC22A12, is a suppressing factor for the development of gout.
Topics: Adenine; Adult; Carrier Proteins; Case-Control Studies; Female; Gene Frequency; Genotype; Gout; Guanine; Heterozygote; Humans; Male; Middle Aged; Mutation; Organic Anion Transporters; Organic Cation Transport Proteins; Uric Acid | 2005 |
Renal tubular toxicity associated with tenofovir assessed using urine-beta 2 microglobulin, percentage of tubular reabsorption of phosphate and alkaline phosphatase levels.
Topics: Absorption; Adenine; Adult; Alkaline Phosphatase; Antiretroviral Therapy, Highly Active; beta 2-Microglobulin; Creatinine; HIV Infections; HIV-1; Humans; Kidney Tubules; Middle Aged; Organophosphonates; Phosphates; Phosphorus; Reverse Transcriptase Inhibitors; Tenofovir; Uric Acid | 2005 |
A novel electrochemical biosensor for the detection of uric acid and adenine.
Topics: Adenine; Biosensing Techniques; Carbon; Electrochemistry; Electrodes; Nanotechnology; Sensitivity and Specificity; Uric Acid | 2006 |
Preferential inhibition of xanthine oxidase by 2-amino-6-hydroxy-8-mercaptopurine and 2-amino-6-purine thiol.
Topics: Adenine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydroxylation; Kinetics; Mercaptopurine; Models, Chemical; Molecular Structure; Substrate Specificity; Thioguanine; Uric Acid; Xanthine; Xanthine Oxidase; Xanthines | 2007 |
Renal tubular dysfunction during long-term adefovir or tenofovir therapy in chronic hepatitis B.
Topics: Adenine; Adult; Aged; Antiviral Agents; Biomarkers; Creatinine; Female; Glomerular Filtration Rate; Hepatitis B, Chronic; Humans; Kidney Tubules; Male; Middle Aged; Organophosphonates; Phosphates; Renal Insufficiency; Tenofovir; Time Factors; Uric Acid | 2012 |
Electrochemical characterization of redox polymer modified electrode developed for monitoring of adenine.
Topics: Adenine; Electric Impedance; Electrochemistry; Electrodes; Ferrous Compounds; Guanine; Hydrogen-Ion Concentration; Microscopy, Electron, Scanning; Oxidation-Reduction; Platinum; Polymers; Polyvinyls; Uric Acid | 2013 |
Urine processing impacts uric acid level in HIV-infected adults: implications for diagnosing tenofovir-associated proximal tubulopathy.
Topics: Adenine; Adult; AIDS-Associated Nephropathy; Anti-HIV Agents; HIV Infections; Humans; Organophosphonates; Sensitivity and Specificity; Specimen Handling; Tenofovir; Time Factors; Uric Acid | 2013 |
Nephroprotective effects of Isaria felina in rats with adenine-induced chronic renal failure.
Topics: Adenine; Animals; Ascomycota; Biological Products; Blood Urea Nitrogen; Cordyceps; Creatinine; Disease Models, Animal; Epidermal Growth Factor; Erythrocyte Count; Fruiting Bodies, Fungal; Hematocrit; Hemoglobins; Kidney; Kidney Failure, Chronic; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transforming Growth Factor beta1; Uric Acid | 2013 |
Low-potential amperometric determination of purine derivatives through surface oxide regeneration method.
Topics: Adenine; Copper; Electrochemical Techniques; Guanine; Hypoxanthine; Limit of Detection; Oxidation-Reduction; Purines; Uric Acid; Xanthine | 2013 |
Arxula adeninivorans recombinant urate oxidase and its application in the production of food with low uric acid content.
Topics: Adenine; DNA, Fungal; Enzyme Stability; Food Handling; Gene Expression Profiling; Hydrogen-Ion Concentration; Hypoxanthine; Molecular Sequence Data; Recombinant Proteins; Saccharomycetales; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Substrate Specificity; Temperature; Urate Oxidase; Uric Acid | 2013 |
Overoxidized polyimidazole/graphene oxide copolymer modified electrode for the simultaneous determination of ascorbic acid, dopamine, uric acid, guanine and adenine.
Topics: Adenine; Ascorbic Acid; Biosensing Techniques; Dopamine; Electrochemical Techniques; Electrodes; Graphite; Guanine; Imidazoles; Limit of Detection; Oxidation-Reduction; Polymers; Uric Acid | 2014 |
Chinese Herbal Formulas Si-Wu-Tang and Er-Miao-San Synergistically Ameliorated Hyperuricemia and Renal Impairment in Rats Induced by Adenine and Potassium Oxonate.
Topics: Adenine; Administration, Oral; Animals; Benzbromarone; Creatinine; Drug Synergism; Drugs, Chinese Herbal; Hyperuricemia; Kidney; Male; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Oxonic Acid; Plant Exudates; Rats; Rats, Sprague-Dawley; Uric Acid; Xanthine Oxidase | 2015 |
Simultaneous Determination of Dopamine, Uric Acid and Guanine at Polyadenine Film Modified Electrode.
Topics: Adenine; Carbon; Dopamine; Electrochemical Techniques; Electrodes; Guanine; Humans; Limit of Detection; Microscopy, Electron, Scanning; Oxidation-Reduction; Reproducibility of Results; Surface Properties; Uric Acid | 2015 |
Taurine decreased uric acid levels in hyperuricemic rats and alleviated kidney injury.
Topics: Acute Kidney Injury; Adenine; Administration, Oral; Animals; Ethambutol; Hyperuricemia; Male; Rats; Rats, Wistar; Taurine; Uric Acid | 2017 |
The antioxidant capacity of erythrocyte concentrates is increased during the first week of storage and correlated with the uric acid level.
Topics: Adenine; Antioxidants; Blood Preservation; Erythrocytes; Glucose; Humans; Mannitol; Sodium Chloride; Uric Acid | 2017 |
Donor-specific individuality of red blood cell performance during storage is partly a function of serum uric acid levels.
Topics: Adenine; Adolescent; Adult; Antioxidants; Biomarkers; Blood Donors; Blood Preservation; Calcium; Citrates; Dynamic Light Scattering; Erythrocytes; Erythrocytes, Abnormal; Extracellular Vesicles; Glucose; Hemolysis; Humans; Male; Mannitol; Oxidative Stress; Phosphates; Reactive Oxygen Species; Uric Acid; Young Adult | 2018 |
Effect and mechanism of dioscin from Dioscorea spongiosa on uric acid excretion in animal model of hyperuricemia.
Topics: Adenine; Animals; Biomarkers; Creatinine; Dioscorea; Diosgenin; Disease Models, Animal; Dose-Response Relationship, Drug; Glucose Transport Proteins, Facilitative; HCT116 Cells; Humans; Hyperuricemia; Intestinal Elimination; Intestinal Mucosa; Intestines; Male; Mice; Organic Anion Transport Protein 1; Organic Anion Transporters; Organic Cation Transport Proteins; Oxonic Acid; Phytotherapy; Plant Extracts; Plants, Medicinal; Rats, Sprague-Dawley; Renal Elimination; Spirostans; Time Factors; Uric Acid; Uricosuric Agents | 2018 |
Recurrence rates of urinary calculi according to stone composition and morphology.
Topics: Adenine; Adolescent; Adult; Age of Onset; Aged; Apatites; Calcium Oxalate; Child; Child, Preschool; Female; France; Humans; Infant; Infant, Newborn; Male; Middle Aged; Recurrence; Spectrophotometry, Infrared; Uric Acid; Urinary Calculi; Young Adult | 2018 |
Ameliorative effect of ursolic acid on renal fibrosis in adenine-induced chronic kidney disease in rats.
Topics: Adenine; Animals; Blood Urea Nitrogen; Collagen Type I; Connective Tissue Growth Factor; Creatinine; Cystatin C; Fibronectins; Fibrosis; Hydroxyproline; Kidney; Lipocalin-2; Male; Organ Size; Rats, Wistar; Renal Insufficiency, Chronic; Transforming Growth Factor beta1; Triterpenes; Uric Acid; Ursolic Acid | 2018 |
Graphene oxide reinforced core-shell structured Ag@Cu
Topics: Adenine; Biosensing Techniques; Catalysis; Copper; Dopamine; Gold; Graphite; Guanine; Nanostructures; Oxidation-Reduction; Uric Acid | 2018 |
Molecular Mechanisms for Species Differences in Organic Anion Transporter 1, OAT1: Implications for Renal Drug Toxicity.
Topics: Adenine; Amino Acids; Animals; Antiviral Agents; Cell Line; Cercopithecidae; Dogs; Drug-Related Side Effects and Adverse Reactions; HEK293 Cells; Humans; Kidney; Kinetics; Macaca fascicularis; Mice; Organic Anion Transport Protein 1; Organophosphonates; Rats; Species Specificity; Uric Acid | 2018 |
Quercetin Treatment Improves Renal Function and Protects the Kidney in a Rat Model of Adenine-Induced Chronic Kidney Disease.
Topics: Adenine; Animals; Antioxidants; Blood Urea Nitrogen; Creatinine; Disease Models, Animal; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Interleukin-6; Kidney; Kidney Function Tests; L-Lactate Dehydrogenase; Male; Parathyroid Hormone; Phosphates; Protective Agents; Proteinuria; Quercetin; Rats, Wistar; Renal Insufficiency, Chronic; Superoxide Dismutase; Uric Acid | 2018 |
Poly(glycine)/graphene oxide modified glassy carbon electrode: Preparation, characterization and simultaneous electrochemical determination of dopamine, uric acid, guanine and adenine.
Topics: Adenine; Carbon; Catalysis; Dopamine; Electrochemical Techniques; Electrodes; Graphite; Guanine; Limit of Detection; Microscopy, Electron, Scanning; Oxidation-Reduction; Oxides; Peptides; Reproducibility of Results; Spectroscopy, Fourier Transform Infrared; Uric Acid | 2018 |
Production Inhibition and Excretion Promotion of Urate by Fucoidan from
Topics: Adenine; Animals; Blood Urea Nitrogen; Creatinine; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Hyperuricemia; Kidney; Laminaria; Liver; Male; Mice; Polysaccharides; Renal Elimination; Treatment Outcome; Uric Acid | 2018 |
The clinical and pathological features of adefovir dipivoxil-related renal impairment
.
Topics: Adenine; Adult; Antiviral Agents; Creatinine; Female; Glycosuria; Hematuria; Hepatitis B, Chronic; Humans; Hypophosphatemia; Kidney Tubules, Proximal; Male; Middle Aged; Mitochondria; Organophosphonates; Phosphorus; Proteinuria; Renal Insufficiency; Uric Acid | 2019 |
Changes of drug pharmacokinetics mediated by downregulation of kidney organic cation transporters Mate1 and Oct2 in a rat model of hyperuricemia.
Topics: Adenine; Animals; Antiporters; Cephalexin; Creatinine; Disease Models, Animal; Down-Regulation; Humans; Hyperuricemia; Kidney; Male; Metformin; Organic Cation Transport Proteins; Organic Cation Transporter 2; Oxonic Acid; Pharmacokinetics; Rats; Rats, Wistar; RNA, Messenger; Uric Acid | 2019 |
Unfavorable Reduction in the Ratio of Endothelin B to A Receptors in Experimental 5/6 Nephrectomy and Adenine Models of Chronic Renal Insufficiency.
Topics: Adenine; Animals; Calcium; Disease Models, Animal; Gene Expression Regulation; Kidney Cortex; Male; Nephrectomy; Phosphates; Rats; Receptor, Endothelin A; Receptor, Endothelin B; Renal Insufficiency, Chronic; Uric Acid | 2020 |
Specificity profile of NAT/NCS2 purine transporters in Sinorhizobium (Ensifer) meliloti.
Topics: Adenine; Biological Transport, Active; Escherichia coli K12; Guanine; Hypoxanthine; Membrane Transport Proteins; Plant Root Nodulation; Rhizosphere; Root Nodules, Plant; Sinorhizobium meliloti; Symporters; Uric Acid; Xanthine | 2020 |
Total glucosides of herbaceous peony (Paeonia lactiflora Pall.) flower attenuate adenine- and ethambutol-induced hyperuricaemia in rats.
Topics: Adenine; Animals; Biomarkers; Disease Models, Animal; Down-Regulation; Ethambutol; Flowers; Glucosides; Hyperuricemia; Kidney; Male; Paeonia; Plant Extracts; Rats, Wistar; Uric Acid; Uricosuric Agents | 2020 |
The Time-Feature of Uric Acid Excretion in Hyperuricemia Mice Induced by Potassium Oxonate and Adenine.
Topics: Adenine; Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; Chromatography, High Pressure Liquid; Creatinine; Disease Models, Animal; Glucose Transport Proteins, Facilitative; Hyperuricemia; Kidney; Mice; Organic Anion Transport Protein 1; Organic Anion Transporters; Oxonic Acid; Sodium-Phosphate Cotransporter Proteins, Type I; Time Factors; Uric Acid | 2020 |
Simultaneous electrochemical detection of guanine and adenine using reduced graphene oxide decorated with AuPt nanoclusters.
Topics: Adenine; Alloys; Animals; Ascorbic Acid; Biosensing Techniques; DNA; Dopamine; Electrochemical Techniques; Electrodes; Gold; Graphite; Guanine; Limit of Detection; Male; Metal Nanoparticles; Nanocomposites; Oxidation-Reduction; Platinum; Salmon; Spermatozoa; Uric Acid | 2021 |
Nano-ZnS decorated hierarchically porous carbon electrocatalyst with multiple enzyme-like activities as a nanozyme sensing platform for simultaneous detection of dopamine, uric acid, guanine, and adenine.
Topics: Adenine; Ascorbic Acid; Carbon; Dopamine; Electrochemical Techniques; Guanine; Humans; Porosity; Uric Acid | 2021 |
Correlation Between Kidney Function and Intestinal Biological Characteristics of Adenine and Folium SennaeInduced Diarrhea Model in Mice.
Topics: Adenine; Animals; Creatinine; Diarrhea; Intestinal Mucosa; Kidney; Mice; Urea; Uric Acid | 2023 |
Corilagin Restrains NLRP3 Inflammasome Activation and Pyroptosis through the ROS/TXNIP/NLRP3 Pathway to Prevent Inflammation.
Topics: Adenine; Adenosine Triphosphate; Anti-Inflammatory Agents; Antioxidants; Arthritis, Gouty; Caspase 1; Humans; Hydrolyzable Tannins; Imiquimod; Inflammasomes; Inflammation; Interleukin-1beta; Lactate Dehydrogenases; Lipopolysaccharides; Nigericin; NLR Family, Pyrin Domain-Containing 3 Protein; Nucleosides; Propidium; Pyroptosis; Reactive Oxygen Species; Uric Acid | 2022 |
Intermediate products of purine metabolism in an experimental model of pancreatic necrosis.
Topics: Adenine; Animals; Guanine; Hypoxanthine; Models, Theoretical; Pancreatitis, Acute Necrotizing; Purines; Rabbits; Uric Acid; Xanthine | 2022 |
A Novel Approach Based on Gut Microbiota Analysis and Network Pharmacology to Explain the Mechanisms of Action of
Topics: Adenine; Animals; Cichorium intybus; Creatinine; Drugs, Chinese Herbal; Ethambutol; Gastrointestinal Microbiome; Hyperuricemia; Molecular Docking Simulation; Network Pharmacology; Rats; RNA, Ribosomal, 16S; Urea; Uric Acid | 2023 |
[Anti-hyperuricemia activity and its mechanism of flavonoid extract from saffron floral bio-residues].
Topics: Adenine; Amino Acids; Animals; Antioxidants; Crocus; Ethambutol; Flavonoids; Hyperuricemia; Kidney; Lipids; Plant Extracts; Rats; Rats, Sprague-Dawley; Uric Acid; Xanthine Oxidase | 2023 |
Roflumilast alleviates adenine-induced chronic kidney disease by regulating inflammatory biomarkers.
Topics: Adenine; Animals; Antioxidants; Biomarkers; Calcium; Creatinine; Kidney; Magnesium Chloride; Male; Rats; Rats, Wistar; Renal Insufficiency, Chronic; Transforming Growth Factor beta; Urea; Uric Acid | 2023 |