adenine and thioinosine

adenine has been researched along with thioinosine in 55 studies

Research

Studies (55)

TimeframeStudies, this research(%)All Research%
pre-199012 (21.82)18.7374
1990's25 (45.45)18.2507
2000's14 (25.45)29.6817
2010's4 (7.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dalske, HF; Scholar, EM1
Hershfield, MS; Seegmiller, JE1
Belt, JA; Cass, CE; Dagnino, L; Gati, WP; Paterson, AR; Vijayalakshmi, D1
Cunha, RA; Sebastião, AM1
Lieberman, M; Wagenknecht, B1
Van Belle, H1
Abd-Elfattah, AS; Hanan, SA; Jessen, ME; Tuchy, G; Wechsler, AS1
Beck, J; Ullman, B1
Pisoni, RL; Thoene, JG1
Cartner, LA; Holliss, DG; Humphrey, SM1
Plagemann, PG; Woffendin, C; Wohlhueter, RM1
Abd-Elfattah, AS; Brunsting, LA; Doherty, NE; Jessen, ME; Lekven, J; Wechsler, AS1
Mohrman, DE1
Aronow, B; Ullman, B1
Aronow, B; Hollingsworth, P; McCartan, K; Patrick, J; Toll, D; Ullman, B1
Abidi, TF; Plagemann, PG; Stollar, V; Woffendin, C1
Jarvis, SM; Martin, BW; Ng, AS1
Abd-Elfattah, AS; Ding, M; Wechsler, AS1
Bökkerink, JP; De Abreu, RA; Keizer-Garritsen, JJ; Lambooy, LH; Stet, EH; Trijbels, FJ; Vogels-Mentink, TM1
Abd-Elfattah, AS; Jessen, ME; Wechsler, AS1
Abd-Elfattah, AS; Wechsler, AS1
Doyle, MP; Duling, BR; Linden, J1
Abd-Elfattah, AS; Bolli, R; Jeroudi, MO; Sekili, S; Sun, JZ; Tang, XL; Zughaib, ME1
Abd-Elfattah, AS; Ding, M; Dyke, CM; Wechsler, AS1
Abd-Elfattah, AS; Aly, HM; Crescenzo, DG; Domkowski, PW; Hopkins, RA; Jones, JL; Messier, RH; Wallace, RB1
Geiger, JD; Gu, JG; Nath, A1
Correia-de-Sá, P; Ribeiro, JA1
Oliveira, CR; Rego, AC; Santos, MS1
Abd-Elfattah, AS; Jessen, ME; Maddox, RP; Rebeyka, IM; Wechsler, AS1
Abd-Elfattah, AS; Jessen, ME; Lekven, J; Wechsler, AS1
Kalsi, KK; Smolenski, RT; Yacoub, MH2
Ashraf, M; Hirai, K1
IJzerman, AP; Pavan, B1
Richardt, G; Schreieck, J1
Deussen, A; Kelm, M; Schäfer, S; Stappert, M1
Callaghan, F; Hourani, SM; Tennant, JP; Turner, C1
Baldwin, SA; Cass, CE; Hyde, RJ; McConkey, GA; McRobert, L; Parker, MD; Yao, SY; Young, JD1
Baldwin, SA; Cass, CE; LaRivière, CG; Parkinson, FE; Sinclair, CJ; Young, JD1
Dhalla, AK; Dodam, JR; Johnson, LR; Jones, AW; Laughlin, MH; Magliola, L; Rubin, LJ1
Keeling, IM; Obermayr, RP; Schneider, B; Spieckermann, PG1
Gasic, JM; Isakovic, AJ; Markovic, ID; Rakic, LM; Rakic, MLj; Redzic, ZB; Segal, MB; Thomas, SA1
Bernard, EA; de Souza, LF; Gelain, DP1
Majumdar, S; Mitra, AK; Pal, D; Tirucherai, GS1
Lobo, MG; Ribeiro, JA; Sebastião, AM1
Bernard, EA; De Souza, LF; Gelain, DP; Jardim, FR; Moreira, JC; Ribeiro, GR; Zim, M1
Cseppento, A; Gesztelyi, R; Hajdú, P; Szabó, JZ; Szentmiklósi, AJ; Zsuga, J1
Choi, JW; Ko, KH; Yoo, BK; Yoon, SY1
Cherubini, E; Giniatullin, R; Kasyanov, AM; Safiulina, VF1
Ghavami, S; Hashemi, M; Karami-Tehrani, F; Los, M; Maddika, S1
Akaike, T; Kato, R; Maeda, T; Tamai, I1
Buyukdeligoz, M; Hocaoglu, N; Kalkan, S; Oransay, K; Tuncok, Y1
Abd-Elfattah, AS; Ding, M; Jessen, ME; Wechsler, AS1
Abd-Elfattah, AS; Brunsting, LA; Goldstein, JP; Jessen, ME; Salter, DR; Tuchy, GE; Wechsler, AS1
Bogo, MR; Bonan, CD; Capiotti, KM; da Costa Schaefer, I; Da Silva, RS; Frantz, JZ; Kist, LW; Menezes, FP; Siebel, AM1

Reviews

1 review(s) available for adenine and thioinosine

ArticleYear
Nucleoside and nucleobase transport in animal cells.
    Biochimica et biophysica acta, 1988, Oct-11, Volume: 947, Issue:3

    Topics: Adenine; Algorithms; Animals; Biological Transport; Dilazep; Dipyridamole; Hypoxanthine; Hypoxanthines; Kinetics; Lidoflazine; Monosaccharide Transport Proteins; Nucleosides; Temperature; Thioinosine; Thionucleosides

1988

Other Studies

54 other study(ies) available for adenine and thioinosine

ArticleYear
Effect of purine compounds on the vascular responsiveness of bovine coronary and lingual arteries.
    Archives internationales de pharmacodynamie et de therapie, 1979, Volume: 238, Issue:2

    Topics: Adenine; Animals; Arteries; Blood Vessels; Cattle; Coronary Vessels; Dipyridamole; Drug Interactions; In Vitro Techniques; Purine Nucleosides; Purine Nucleotides; Thioinosine; Tongue

1979
Coordinate regulation of the proximal and distal steps of the pathway of purine synthesis de nono in WI-L2 human lymphoblasts.
    Advances in experimental medicine and biology, 1977, Volume: 76A

    Topics: Adenine; Adenine Nucleotides; Adenosine Kinase; Azaserine; Cell Line; Feedback; Formates; Guanine; Hypoxanthines; Inosine Nucleotides; Kinetics; Ligases; Lymphocytes; Phosphoribosyl Pyrophosphate; Purine Nucleotides; Purines; Thioinosine

1977
L1210/B23.1 cells express equilibrative, inhibitor-sensitive nucleoside transport activity and lack two parental nucleoside transport activities.
    The Journal of biological chemistry, 1992, Aug-25, Volume: 267, Issue:24

    Topics: Adenine; Adenosine; Animals; Antiviral Agents; Biological Transport; Carrier Proteins; Cell Membrane; Clone Cells; Formycins; Kinetics; Leukemia L1210; Membrane Proteins; Mice; Mutagenesis; Nucleoside Transport Proteins; Nucleosides; Thioinosine; Thymidine; Tumor Cells, Cultured; Vidarabine

1992
Extracellular metabolism of adenine nucleotides and adenosine in the innervated skeletal muscle of the frog.
    European journal of pharmacology, 1991, May-02, Volume: 197, Issue:1

    Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cations; Coformycin; Dipyridamole; In Vitro Techniques; Inosine Monophosphate; Kinetics; Muscles; Piperazines; Rana ridibunda; Sodium-Potassium-Exchanging ATPase; Thioinosine

1991
Adenine nucleotide degradation in cultured chick heart muscle cells.
    Molecular and cellular biochemistry, 1991, Oct-16, Volume: 107, Issue:2

    Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cells, Cultured; Chick Embryo; Chromatography, High Pressure Liquid; Dipyridamole; Glycolysis; Inosine; Myocardium; Oxidative Phosphorylation; Phosphorylation; Thioinosine

1991
ATP derangement versus free radical-mediated injury.
    Circulation, 1991, Volume: 84, Issue:5

    Topics: Adenine; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Animals; Biological Transport; Free Radicals; Myocardial Reperfusion Injury; Thioinosine

1991
Is adenosine 5'-triphosphate derangement or free-radical-mediated injury the major cause of ventricular dysfunction during reperfusion? Role of adenine nucleoside transport in myocardial reperfusion injury.
    Circulation, 1990, Volume: 82, Issue:5 Suppl

    Topics: Adenine; Adenine Nucleotides; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Affinity Labels; Animals; Dogs; Female; Free Radicals; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Thioinosine; Ventricular Function, Left

1990
Expression of a novel high affinity purine base transport system in mutant mouse S49 cells does not require a functional nucleoside transporter.
    Advances in experimental medicine and biology, 1989, Volume: 253B

    Topics: Adenine; Animals; Biological Transport; Clone Cells; Dipyridamole; Dose-Response Relationship, Drug; Gene Expression; Guanine; Hybridization, Genetic; Hypoxanthine; Hypoxanthines; Inosine; Lymphoma; Mice; Mice, Inbred BALB C; Mutation; Phenotype; T-Lymphocytes; Thioinosine; Tumor Cells, Cultured

1989
Detection and characterization of a nucleoside transport system in human fibroblast lysosomes.
    The Journal of biological chemistry, 1989, Mar-25, Volume: 264, Issue:9

    Topics: Adenine; Adenosine; Amino Acid Transport Systems; Biological Transport; Carrier Proteins; Cell Line; Dipyridamole; Fibroblasts; Humans; Kinetics; Lysosomes; Nucleosides; Substrate Specificity; Thioinosine

1989
The influence of inhibitors of the ATP degradative pathway on recovery of function and high energy phosphate after transient ischemia in the rat heart.
    Journal of molecular and cellular cardiology, 1986, Volume: 18 Suppl 4

    Topics: 5'-Nucleotidase; Acute Disease; Adenine; Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Triphosphate; Adenylate Kinase; Animals; Coronary Circulation; Coronary Disease; Dinucleoside Phosphates; Male; Nucleotidases; Rats; Rats, Inbred Strains; Thioinosine

1986
Myocardial reperfusion injury. Role of myocardial hypoxanthine and xanthine in free radical-mediated reperfusion injury.
    Circulation, 1988, Volume: 78, Issue:5 Pt 2

    Topics: Adenine; Adenine Nucleotides; Animals; Coronary Disease; Dogs; Female; Free Radicals; Heart; Heart Ventricles; Hypoxanthine; Hypoxanthines; Male; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; Thioinosine; Xanthine; Xanthines

1988
Adenosine handling in interstitia of cremaster muscle studied by bioassay.
    The American journal of physiology, 1988, Volume: 254, Issue:2 Pt 2

    Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Arterioles; Biological Assay; Cricetinae; Diffusion; Dipyridamole; Extracellular Space; Kinetics; Methods; Muscles; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Thioinosine; Vasodilation

1988
Role of the nucleoside transport function in the transport and salvage of purine nucleobases.
    The Journal of biological chemistry, 1986, Feb-15, Volume: 261, Issue:5

    Topics: Adenine; Animals; Antimetabolites, Antineoplastic; Azaserine; Biological Transport; Cell Line; Dipyridamole; Hypoxanthine; Hypoxanthines; Mice; Nucleosides; Purines; T-Lymphocytes; Thioinosine

1986
Expression of a novel high-affinity purine nucleobase transport function in mutant mammalian T lymphoblasts.
    Molecular and cellular biology, 1986, Volume: 6, Issue:8

    Topics: Adenine; Animals; Azaserine; Biological Transport, Active; Cell Line; Dipyridamole; Guanine; Hypoxanthine; Hypoxanthines; Kinetics; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Mutation; Phenotype; Purine Nucleosides; T-Lymphocytes; Thioinosine

1986
Nucleoside and nucleobase transport and metabolism in wild type and nucleoside transport-deficient Aedes albopictus cells.
    Biochimica et biophysica acta, 1987, Mar-12, Volume: 897, Issue:3

    Topics: Adenine; Adenosine Triphosphate; Aedes; Animals; Biological Transport; Carrier Proteins; Hypoxanthine; Hypoxanthines; Kinetics; Membrane Proteins; Mutation; Nucleoside Transport Proteins; Nucleosides; Thioinosine; Thymidine; Uracil; Uridine

1987
2-Chloroadenosine, a permeant for the nucleoside transporter.
    Biochemical pharmacology, 1985, Sep-15, Volume: 34, Issue:18

    Topics: 2-Chloroadenosine; Adenine; Adenosine; Biological Transport; Blood Proteins; Carrier Proteins; Erythrocyte Membrane; Erythrocytes; Humans; Kinetics; Membrane Proteins; Nucleoside Transport Proteins; Thioinosine; Uridine

1985
Intermittent aortic crossclamping prevents cumulative adenosine triphosphate depletion, ventricular fibrillation, and dysfunction (stunning): is it preconditioning?
    The Journal of thoracic and cardiovascular surgery, 1995, Volume: 110, Issue:2

    Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Animals; Aorta; Constriction; Dogs; Inosine; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardial Stunning; Myocardium; Thioinosine; Ventricular Dysfunction, Left; Ventricular Fibrillation; Ventricular Function, Left

1995
Reversal of methylmercaptopurine ribonucleoside cytotoxicity by purine ribonucleosides and adenine.
    Biochemical pharmacology, 1995, Jan-06, Volume: 49, Issue:1

    Topics: Adenine; Adenosine; Antineoplastic Agents; Cell Division; Cell Survival; Cells, Cultured; Guanosine; Humans; Inosine; Mercaptopurine; Methylthioinosine; Nucleosides; Nucleotides; Purine Nucleosides; Ribonucleosides; T-Lymphocytes; Thioinosine; Thionucleotides

1995
Nucleoside trapping during reperfusion prevents ventricular dysfunction, "stunning," in absence of adenosine. Possible separation between ischemic and reperfusion injury.
    The Journal of thoracic and cardiovascular surgery, 1994, Volume: 108, Issue:2

    Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Affinity Labels; Animals; Biological Transport, Active; Dogs; Female; Inosine; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Stunning; Purinones; Random Allocation; Thioinosine; Ventricular Function, Left

1994
Separation between ischemic and reperfusion injury by site specific entrapment of endogenous adenosine and inosine using NBMPR and EHNA.
    Journal of cardiac surgery, 1994, Volume: 9, Issue:3 Suppl

    Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Dogs; Female; Heart; Inosine; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Thioinosine; Ventricular Function, Left

1994
Nucleoside-induced arteriolar constriction: a mast cell-dependent response.
    The American journal of physiology, 1994, Volume: 266, Issue:5 Pt 2

    Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Affinity Labels; Animals; Arterioles; Cricetinae; Dose-Response Relationship, Drug; In Vitro Techniques; Inosine; Male; Mast Cells; Mesocricetus; Methylene Blue; Mouth; Muscle, Smooth, Vascular; p-Methoxy-N-methylphenethylamine; Purinergic P1 Receptor Antagonists; Thioinosine; Vasoconstriction

1994
Augmentation of endogenous adenosine attenuates myocardial 'stunning' independently of coronary flow or hemodynamic effects.
    Circulation, 1993, Volume: 88, Issue:5 Pt 1

    Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Coronary Circulation; Dogs; Heart; Hemodynamics; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Stunning; Nucleosides; Thioinosine

1993
Protection of the stunned myocardium. Selective nucleoside transport blocker administered after 20 minutes of ischemia augments recovery of ventricular function.
    Circulation, 1993, Volume: 88, Issue:5 Pt 2

    Topics: Adenine; Adenosine Triphosphate; Affinity Labels; Animals; Chromatography, High Pressure Liquid; Dogs; Drug Therapy, Combination; Female; Inosine; Male; Myocardial Reperfusion; Myocardial Stunning; Myocardium; Thioinosine; Time Factors

1993
Inhibition of adenosine deaminase and nucleoside transport. Utility in a model of homograft cardiac valve preimplantation processing.
    The Journal of thoracic and cardiovascular surgery, 1993, Volume: 105, Issue:6

    Topics: Adenine; Adenine Nucleotides; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Animals; Biological Transport, Active; Female; Heart Valves; Organ Preservation; Purine Nucleosides; Swine; Thioinosine; Transplantation, Homologous

1993
Characterization of inhibitor-sensitive and -resistant adenosine transporters in cultured human fetal astrocytes.
    Journal of neurochemistry, 1996, Volume: 67, Issue:3

    Topics: Adenine; Adenosine; Affinity Labels; Astrocytes; Biological Transport; Carrier Proteins; Cells, Cultured; Dilazep; Dipyridamole; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fetus; Humans; Kinetics; Membrane Proteins; Nucleoside Transport Proteins; Thioinosine; Tritium; Tubercidin; Vasodilator Agents

1996
Adenosine uptake and deamination regulate tonic A2a receptor facilitation of evoked [3H]acetylcholine release from the rat motor nerve terminals.
    Neuroscience, 1996, Volume: 73, Issue:1

    Topics: Acetylcholine; Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Affinity Labels; Animals; Deamination; Diaphragm; Electric Stimulation; Enzyme Inhibitors; Female; In Vitro Techniques; Male; Motor Neurons; Phrenic Nerve; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, Purinergic P1; Thioinosine

1996
Adenosine triphosphate degradation products after oxidative stress and metabolic dysfunction in cultured retinal cells.
    Journal of neurochemistry, 1997, Volume: 69, Issue:3

    Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Cell Hypoxia; Cells, Cultured; Chick Embryo; Enzyme Inhibitors; Glucose; Hypoxanthine; Inosine; Iodoacetates; Iodoacetic Acid; Ischemia; Kinetics; Oligomycins; Oxidative Stress; Retina; Thioinosine

1997
Role of nucleoside transport and purine release in a rabbit model of myocardial stunning.
    Molecular and cellular biochemistry, 1998, Volume: 180, Issue:1-2

    Topics: Adenine; Adenine Nucleotides; Adenosine Deaminase Inhibitors; Animals; Carrier Proteins; Dogs; Enzyme Inhibitors; Female; Heart; Hemodynamics; Male; Membrane Proteins; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Stunning; Myocardium; Nucleoside Transport Proteins; Purines; Rabbits; Thioinosine

1998
Differential cardioprotection with selective inhibitors of adenosine metabolism and transport: role of purine release in ischemic and reperfusion injury.
    Molecular and cellular biochemistry, 1998, Volume: 180, Issue:1-2

    Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Biological Transport; Carrier Proteins; Dogs; Enzyme Inhibitors; Membrane Proteins; Models, Cardiovascular; Myocardial Ischemia; Myocardial Reperfusion Injury; Nucleoside Transport Proteins; Purines; Thioinosine

1998
Effects of nucleoside transport inhibitors and adenine/ribose supply on ATP concentration and adenosine production in cardiac myocytes.
    Molecular and cellular biochemistry, 1998, Volume: 180, Issue:1-2

    Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Biological Transport; Carrier Proteins; Dipyridamole; Enzyme Inhibitors; Membrane Proteins; Myocardium; NAD; Nucleoside Transport Proteins; Rats; Rats, Sprague-Dawley; Ribose; Thioinosine

1998
Effects of nucleoside transport inhibitors and adenine/ribose on ATP concentration and adenosine production in cardiac myocytes.
    Advances in experimental medicine and biology, 1998, Volume: 431

    Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Animals; Biological Transport; Cells, Cultured; Dipyridamole; Heart; Myocardium; Rats; Rats, Sprague-Dawley; Thioinosine

1998
Modulation of adenosine effects in attenuation of ischemia and reperfusion injury in rat heart.
    Journal of molecular and cellular cardiology, 1998, Volume: 30, Issue:9

    Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Enzyme Inhibitors; Heart; Heart Rate; In Vitro Techniques; Isoenzymes; L-Lactate Dehydrogenase; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Organophosphates; Purines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Stroke Volume; Superoxides; Thioinosine; Xanthine Oxidase

1998
Processing of adenosine receptor agonists in rat and human whole blood.
    Biochemical pharmacology, 1998, Dec-15, Volume: 56, Issue:12

    Topics: Adenine; Adenosine; Adenosine Kinase; Aminohydrolases; Animals; Blood; Deoxyadenosines; Enzyme Inhibitors; Humans; Purinergic P1 Receptor Agonists; Rats; Thioinosine

1998
Endogenous adenosine reduces the occurrence of ischemia-induced ventricular fibrillation in rat heart.
    Journal of molecular and cellular cardiology, 1999, Volume: 31, Issue:1

    Topics: Adenine; Adenosine; Aminoimidazole Carboxamide; Animals; Caffeine; Creatine Kinase; Electrocardiography; Enzyme Inhibitors; Hypoxanthine; Inosine; Male; Myocardial Ischemia; Myocardium; Perfusion; Rats; Rats, Wistar; Reperfusion Injury; Ribonucleosides; Theophylline; Thioinosine; Thiophenes; Time Factors; Ventricular Fibrillation; Xanthines

1999
Quantification of extracellular and intracellular adenosine production: understanding the transmembranous concentration gradient.
    Circulation, 1999, Apr-20, Volume: 99, Issue:15

    Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Biological Transport; Bradykinin; Coronary Circulation; Cytosol; Depression, Chemical; Dipyridamole; Drug Synergism; Enzyme Inhibitors; Extracellular Space; Guinea Pigs; Heart; Models, Biological; Myocardium; Osmolar Concentration; Oxygen; Oxygen Consumption; Piperazines; Thioinosine; Tubercidin

1999
Effects of allopurinol, erythro-9-(2-hydroxy-3-nonyl)adenine and S-(4-nitrobenzyl)-6-thioinosine on the degradation of adenosine 5'-triphosphate in the rat colon muscularis mucosae.
    Journal of autonomic pharmacology, 1999, Volume: 19, Issue:4

    Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Allopurinol; Animals; Colon; Enzyme Inhibitors; Half-Life; In Vitro Techniques; Intestinal Mucosa; Muscle, Smooth; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Thioinosine

1999
Identification of a nucleoside/nucleobase transporter from Plasmodium falciparum, a novel target for anti-malarial chemotherapy.
    The Biochemical journal, 2000, Jul-01, Volume: 349, Issue:Pt 1

    Topics: Adenine; Amino Acid Sequence; Animals; Antimalarials; Biological Transport; Blotting, Southern; Carrier Proteins; Cations; Cell Membrane; Cloning, Molecular; Dilazep; Dipyridamole; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Nucleobase, Nucleoside, Nucleotide, and Nucleic Acid Transport Proteins; Nucleosides; Phylogeny; Piperazines; Plasmodium falciparum; Platelet Aggregation Inhibitors; Protein Structure, Secondary; Protozoan Proteins; Sequence Homology, Amino Acid; Substrate Specificity; Thioinosine; Time Factors; Uridine; Vasodilator Agents; Xenopus

2000
Purine uptake and release in rat C6 glioma cells: nucleoside transport and purine metabolism under ATP-depleting conditions.
    Journal of neurochemistry, 2000, Volume: 75, Issue:4

    Topics: Adenine; Adenosine; Adenosine Triphosphate; AMP Deaminase; Animals; Carrier Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Equilibrative Nucleoside Transport Proteins; Equilibrative-Nucleoside Transporter 2; Formycins; Glioma; Hypoxanthine; Inosine; Iodoacetates; Nucleosides; Phosphodiesterase Inhibitors; Purines; Rats; Reverse Transcriptase Polymerase Chain Reaction; Sodium; Sodium Cyanide; Thioinosine; Tumor Cells, Cultured

2000
Selective transport of adenosine into porcine coronary smooth muscle.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 279, Issue:3

    Topics: 2-Chloroadenosine; Adenine; Adenosine; Animals; Biological Transport; Carrier Proteins; Coronary Vessels; Dinoprost; Dipyridamole; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Female; In Vitro Techniques; Muscle, Smooth, Vascular; Purinergic P1 Receptor Agonists; Substrate Specificity; Swine; Thioinosine; Vasoconstriction; Vasodilation; Vasodilator Agents

2000
Postischemic cardiac function recovery in the isolated rat heart: effects of adenosine deaminase and nucleoside transport inhibition.
    Langenbeck's archives of surgery, 2000, Volume: 385, Issue:8

    Topics: Adenine; Adenosine Deaminase; Affinity Labels; Animals; Cardioplegic Solutions; Disease Models, Animal; Enzyme Inhibitors; Glucose; In Vitro Techniques; Male; Mannitol; Myocardial Reperfusion Injury; Myocardium; Potassium Chloride; Procaine; Rats; Rats, Sprague-Dawley; Thioinosine

2000
The kinetics of hypoxanthine transport across the perfused choroid plexus of the sheep.
    Brain research, 2002, Jan-25, Volume: 925, Issue:2

    Topics: Adenine; Allopurinol; Animals; Binding, Competitive; Biological Transport; Carbon Radioisotopes; Choroid Plexus; Dose-Response Relationship, Drug; Hypoxanthine; In Vitro Techniques; Mannitol; Perfusion; Sheep; Sodium; Thioinosine; Thymine; Tritium; Uracil; Xanthine Oxidase

2002
Extracellular purines from cells of seminiferous tubules.
    Molecular and cellular biochemistry, 2003, Volume: 245, Issue:1-2

    Topics: 5'-Nucleotidase; Adenine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Animals; Cells, Cultured; Dipyridamole; Enzyme Inhibitors; Extracellular Space; Germ Cells; Kinetics; Male; Paracrine Communication; Phosphodiesterase Inhibitors; Purines; Rats; Rats, Wistar; Receptors, Purinergic; Seminiferous Tubules; Sertoli Cells; Thioinosine

2003
Functional differences in nucleoside and nucleobase transporters expressed on the rabbit corneal epithelial cell line (SIRC) and isolated rabbit cornea.
    AAPS pharmSci, 2003, Volume: 5, Issue:2

    Topics: Adenine; Animals; Biological Transport; Cornea; Epithelium, Corneal; Ganciclovir; Male; Membrane Transport Proteins; Nucleosides; Nucleotide Transport Proteins; Rabbits; Sodium; Thioinosine; Thymidine; Tritium

2003
Endogenous adenosine modulation of 22Na uptake by rat brain synaptosomes.
    Neurochemical research, 2003, Volume: 28, Issue:10

    Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Brain; In Vitro Techniques; Rats; Rats, Wistar; Sodium; Sodium Radioisotopes; Synaptosomes; Thioinosine

2003
Extracellular inosine is modulated by H2O2 and protects sertoli cells against lipoperoxidation and cellular injury.
    Free radical research, 2004, Volume: 38, Issue:1

    Topics: Adenine; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Animals; Cell Survival; Cells, Cultured; Dipyridamole; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydrogen Peroxide; Inosine; Lipid Peroxidation; Male; Niacinamide; Oxidants; Oxidative Stress; Rats; Sertoli Cells; Thioinosine

2004
Positive inotropic effect of the inhibition of cyclic GMP-stimulated 3',5'-cyclic nucleotide phosphodiesterase (PDE2) on guinea pig left atria in eu- and hyperthyroidism.
    General physiology and biophysics, 2003, Volume: 22, Issue:4

    Topics: Adenine; Adenosine; Animals; Cardiotonic Agents; Culture Techniques; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 2; Guinea Pigs; Heart Atria; Hyperthyroidism; Male; Myocardial Contraction; Phosphoric Diester Hydrolases; Thioinosine

2003
Protective effect of adenosine and purine nucleos(t)ides against the death by hydrogen peroxide and glucose deprivation in rat primary astrocytes.
    Neuroscience research, 2005, Volume: 51, Issue:1

    Topics: Adenine; Adenosine; Analysis of Variance; Animals; Animals, Newborn; Astrocytes; Benzimidazoles; Carbocyanines; Cell Death; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Glucose; Hydrogen Peroxide; In Vitro Techniques; L-Lactate Dehydrogenase; Membrane Potentials; Mitochondria; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Rats; Rats, Sprague-Dawley; Theobromine; Thioinosine; Time Factors; Xanthines

2005
Adenosine down-regulates giant depolarizing potentials in the developing rat hippocampus by exerting a negative control on glutamatergic inputs.
    Journal of neurophysiology, 2005, Volume: 94, Issue:4

    Topics: Action Potentials; Adenine; Adenosine; Adenosine Triphosphate; Analgesics; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutamic Acid; Hippocampus; In Vitro Techniques; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Wistar; Thioinosine; Xanthines

2005
Adenosine and deoxyadenosine induces apoptosis in oestrogen receptor-positive and -negative human breast cancer cells via the intrinsic pathway.
    Cell proliferation, 2005, Volume: 38, Issue:5

    Topics: Adenine; Adenosine; Apoptosis; Breast Neoplasms; Caspase 3; Caspase 9; Caspases; Cell Line, Tumor; Cell Proliferation; Deoxyadenosines; Dose-Response Relationship, Drug; Humans; Receptors, Estrogen; Thioinosine; Time Factors

2005
Characterization of novel Na+-dependent nucleobase transport systems at the blood-testis barrier.
    American journal of physiology. Endocrinology and metabolism, 2006, Volume: 290, Issue:5

    Topics: Adenine; Animals; Biological Transport; Blood-Testis Barrier; Cytosine; Guanine; Hypoxanthine; Kinetics; Male; Meglumine; Nucleobase Transport Proteins; Nucleoside Transport Proteins; Purine Nucleosides; Pyrimidine Nucleosides; Rats; Rats, Inbred Strains; Sertoli Cells; Sodium; Thioinosine; Thymine; Uracil; Uridine

2006
Adenosine-mediated cardiovascular toxicity in amitriptyline-poisoned rats.
    Drug and chemical toxicology, 2012, Volume: 35, Issue:4

    Topics: Adenine; Adenosine; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Arterial Pressure; Glucose; Heart Rate; Infusions, Intravenous; Long QT Syndrome; Male; Rats; Rats, Wistar; Thioinosine; Time Factors

2012
On-pump inhibition of es-ENT1 nucleoside transporter and adenosine deaminase during aortic crossclamping entraps intracellular adenosine and protects against reperfusion injury: role of adenosine A1 receptor.
    The Journal of thoracic and cardiovascular surgery, 2012, Volume: 144, Issue:1

    Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Chromatography, High Pressure Liquid; Constriction; Disease Models, Animal; Dogs; Ischemic Preconditioning; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardial Stunning; Nucleoside Transport Proteins; Receptor, Adenosine A1; Theophylline; Thioinosine; Xanthines

2012
Hot shot induction and reperfusion with a specific blocker of the es-ENT1 nucleoside transporter before and after hypothermic cardioplegia abolishes myocardial stunning in acutely ischemic hearts despite metabolic derangement: hot shot drug delivery befor
    The Journal of thoracic and cardiovascular surgery, 2013, Volume: 146, Issue:4

    Topics: Adenine; Adenosine Triphosphate; Animals; Cold Ischemia; Disease Models, Animal; Dogs; Equilibrative Nucleoside Transporter 1; Female; Heart Arrest, Induced; Hypothermia, Induced; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardial Stunning; Myocardium; Recovery of Function; Thioinosine; Time Factors; Ventricular Function, Left; Warm Ischemia

2013
Role of adenosine signaling on pentylenetetrazole-induced seizures in zebrafish.
    Zebrafish, 2015, Volume: 12, Issue:2

    Topics: Adenine; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine Diphosphate; Animals; Benzyl Compounds; Convulsants; Dipyridamole; Gene Expression Regulation; Genes, fos; Pentylenetetrazole; Phenethylamines; Phosphodiesterase Inhibitors; Seizures; Signal Transduction; Thioinosine; Xanthines; Zebrafish

2015