adenine has been researched along with tenofovir diphosphate in 71 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 45 (63.38) | 24.3611 |
| 2020's | 26 (36.62) | 2.80 |
| Authors | Studies |
|---|---|
| Berger, D; Bredeek, UF; Callebaut, C; DeJesus, E; Fordyce, MW; Markowitz, M; Ramanathan, S; Rhee, MS; Ruane, PJ; Yale, K; Zhong, L | 1 |
| Gao, Y; Katz, DF | 1 |
| Anderson, PL; Bushman, LR; García-Lerma, JG; Glidden, DV; Heneine, W | 1 |
| Bodwell, JE; Fahey, JV; Kashuba, AD; Rodriguez-Garcia, M; Shen, Z; Wira, CR | 1 |
| Anderson, PL; Bushman, LR; Caraway, P; Castillo-Mancilla, JR; Gardner, EM; Meditz, AL; Predhomme, J; Searls, K; Zheng, JH | 1 |
| Burns, RN; Chaturvedula, A; Hendrix, CW | 1 |
| Babusis, D; Hao, J; Lepist, EI; Murakami, E; Park, Y; Ray, AS; Wang, T | 1 |
| Acosta, EP; Armstrong, WS; Jiang, Y; Lahiri, CD; Marconi, VC; Ofotokun, I; Sanford, S; Schinazi, RF; Sheth, AN; Tao, S; Vunnava, A | 1 |
| Amara, A; Back, D; Boffito, M; Dickinson, L; Else, L; Higgs, C; Jackson, A; Karolia, Z; Khoo, S; Moyle, G; Yapa, HM | 1 |
| Amico, KR; Anderson, PL; Bacon, O; Blue, RW; Buchbinder, S; Cardenas, G; Chege, W; Cohen, SE; Coleman, ME; Doblecki-Lewis, S; Elion, R; Estrada, Y; Feaster, DJ; Grant, R; Kolber, MA; Liegler, T; Liu, AY; Matheson, T; Philip, SS; Postle, BS; Rawlings, MK; Trainor, N; Vittinghoff, E | 1 |
| Anderson, PL; Bushman, LR; Castillo-Mancilla, J; Guida, LA; Kiser, JJ; Klein, B; McAllister, K; Meditz, A; Rower, C; Zheng, JH | 1 |
| Callebaut, C; Cox, S; Das, M; Margot, N; McCallister, S; Miller, MD | 1 |
| Cottrell, ML; Emerson, CW; Garrett, KL; Gay, C; Kashuba, ADM; McCallister, S; Peery, A; Prince, HMA; Rooney, JF; Schauer, A; Sykes, C | 1 |
| Chen, Q; Jin, X; Ouyang, B; Peng, Y; Sun, J; Wang, G; Zhang, J; Zhen, L; Zhou, F | 1 |
| Achterbergh, RCA; Anderson, PL; Cornelissen, M; de Bree, GJ; de Vries, HJC; Hoornenborg, E; Jurriaans, S; Kootstra, NA; Prins, JM; Prins, M; Reiss, P; Woittiez, LR | 1 |
| Anderson, PL; Buchbinder, S; Bushman, LR; Campbell, K; Castillo-Mancilla, JR; Gardner, EM; Ibrahim, M; Kiser, JJ; Liu, AY; MaWhinney, S; McHugh, C; Morrow, M; Seifert, SM; Wagner, T | 1 |
| Brewers, LM; Kashuba, ADM; Nicol, MR; Sykes, C | 1 |
| Anderson, P; Best, BM; Blumenthal, J; Collins, D; Corado, K; Daar, ES; Dubé, MP; Ellorin, E; Haubrich, R; Jain, S; Milam, J; Moore, DJ; Morris, SR; Sun, X; Young, J | 1 |
| Bodwell, J; Kashuba, ADM; Patel, MV; Rodriguez-Garcia, M; Shen, Z; Wira, CR | 1 |
| Bakshi, RP; Breakey, J; Fuchs, EJ; Jois, B; Manohar, M; Marzinke, MA | 1 |
| Barth, A; Lai, MT; Ma, B; McHale, CM | 1 |
| Anderson, SM; Chandra, N; Cottrell, M; Doncel, GF; Kashuba, A; Kimble, T; Schwartz, JL; Sykes, C; Thurman, AR; Yousefieh, N | 1 |
| Anderson, PL; Brainard, DM; Bushman, LR; Castillo-Mancilla, JR; Chung, RT; Fierer, DS; Hughes, MD; Kim, AY; Kiser, JJ; MacBrayne, CE; Marks, KM; Naggie, S; Peters, MG; Seifert, SM | 1 |
| Balar, B; Dai, JY; Dezzutti, CS; Galaska, B; Hendrix, CW; Justman, JE; Kunjara Na Ayudhya, RP; Levy, L; Marzinke, MA; McGowan, I; Mushamiri, I; Nair, GL; Pan, Z; Piper, JM; Schwartz, JL | 1 |
| Bensouda, S; Cone, RA; Date, AA; Ensign, LM; Fuchs, EJ; Gumber, S; Hanes, J; Hendrix, C; Hoang, T; Marzinke, M; Ortiz, JO; Rohan, L; Villinger, F; Xiao, P; Young, TW | 1 |
| Anderson, PL; Asiimwe, S; Baeten, JM; Bukusi, EA; Celum, C; Donnell, D; Haberer, JE; Heffron, R; Hendrix, CW; Katabira, E; Marzinke, MA; Mugo, NR; Mugwanya, K; Pyra, M; Thomas, KK | 1 |
| Bumpus, NN; Fuchs, EJ; Hendrix, CW; Seneviratne, HK | 1 |
| Anderson, PL; Arduino, RC; Ballerini, A; Bruno, G; Bushman, LR; Chua, CYX; Di Trani, N; Filgueira, CS; Folci, M; Gao, S; Grattoni, A; Gupte, M; Hood, RL; Hu, M; Jain, P; Marzinke, MA; Nehete, P; Sastry, JK; Shelton, K; Susnjar, A | 1 |
| Anderson, PL; Bushman, LR; Castillo-Mancilla, JR; Coleman, SS; Coyle, RP; Ellison, L; Gardner, EM; Kiser, JJ; Mawhinney, S; Morrow, M; Zheng, JH | 3 |
| Arrington-Sanders, R; Hosek, S; Patki, A; Perumean-Chaney, SE; Wilson, CM | 1 |
| Bodwell, J; Patel, MV; Rodriguez-Garcia, M; Shen, Z; Wira, CR | 1 |
| Anderson, PL; Bushman, LR; Castillo-Mancilla, JR; Coleman, SS; Coyle, RP; Ellison, L; Gardner, EM; Kiser, JJ; Mawhinney, S; Morrow, M; Schneck, CD; Zheng, JH | 1 |
| Alfarisi, O; Boffito, M; Cerrone, M; Flexner, C; Maartens, G; Marzinke, MA; Neary, M; Owen, A; Parsons, TL; Pozniak, A | 1 |
| Anderson, PL; Blumenthal, J; Corado, K; Dubé, MP; Ellorin, EE; Hassan, A; Hoenigl, M; Moore, DJ; Morris, SR | 1 |
| Abrams, EJ; Brittain, K; Gomba, Y; Hu, NC; Maartens, G; Myer, L; Norman, J; Orrell, C; Phillips, TK; Sinxadi, P; Wiesner, L; Zerbe, A | 1 |
| Amico, KR; Anderson, PL; Beymer, MR; Bolan, R; Bushman, LR; Goodman-Meza, D; Jordan, WC; Kofron, RM; Landovitz, RJ; Psaros, C; Rooney, JF; Wohl, AR | 1 |
| Adams, JL; Chun, TW; Cottrell, ML; Dellon, ES; Gay, C; Huiting, E; Kashuba, ADM; Maffuid, K; Peery, AF; Poliseno, A; Prince, HMA; Schauer, AP; Stanczyk, FZ; Sykes, C | 1 |
| Burack, JH; Erguera, X; Frazier, R; Grant, R; Horowitz, J; Kang Dufour, MS; Kennedy, K; Koester, KA; Myers, JJ; Packard, R; Udoh, I | 1 |
| Alexander, K; Anderson, PL; Brooks, KM; Bushman, LR; Castillo-Mancilla, JR; Ellison, L; Hosek, S; Huhn, GD; Ibrahim, ME; Kerr, BJ; Kiser, JJ; MaWhinney, S; McHugh, C; Tilden, S | 1 |
| Anderson, PL; Bacon, O; Buchbinder, SP; Cohen, S; Coleman, ME; Elion, R; Gandhi, M; Glidden, DV; Kolber, MA; Liu, AY; Scott, H; Spinelli, MA; Vittinghoff, E | 1 |
| Anderson, SM; Doncel, GF; Gajer, P; Marzinke, MA; Ravel, J; Schwartz, JL; Thurman, AR; Yousefieh, N | 1 |
| Beksinska, M; Brown, TT; Eneh, P; Fowler, MG; Isingel, E; Kabwigu, S; Kaiser, T; Kiweewa Matovu, F; Nakalega, R; Nicol, MR; Staley, C; Sykes, C | 1 |
| Bumpus, NN; Chaturvedula, A; Fossler, MJ; Goti, V; Haberer, JE; Hendrix, CW; Mallayasamy, S; Marzinke, MA; Sale, M | 1 |
| Kearney, B; Kolaris, C; Ling, KHJ; Majeed, SR; Tarnowski, T; Xiao, D; Zondlo, S | 1 |
| Aldern, KA; Beadle, JR; Hostetler, KY; Schooley, RT; Valiaeva, N; Zhang, XQ | 1 |
| Anderson, PL; Bushman, LR; Cooks, RG; Ouyang, Z; Pandey, S; Pu, F | 1 |
| Aizire, J; Brooks, KM; Butler, K; Cababasay, M; Fenton, T; Flynn, PM; Fowler, MG; Kiser, JJ; Mirochnick, M; Siberry, GK | 1 |
| Bardon, A; Drain, PK; Fernandez Suarez, M; Marshall, L; Sandlin, RD; Sevenler, D; Toner, M | 1 |
| Anderson, PL; Castillo-Mancilla, J; Chai, PR; Gandhi, M; Haberer, JE; Spinelli, MA | 1 |
| Anderson, PL; Brooks, KM; Bushman, LR; Castillo-Mancilla, J; Ibrahim, ME; Kiser, JJ; MaWhinney, S; McCallister, S; McHugh, C; Morrow, M; Yager, J | 1 |
| Anderson, PL; Bhasin, S; Defechereux, PA; Deutsch, MB; Glidden, DV; Grant, RM; O'Neal, J; Pellegrini, M; Sevelius, J; Yager, J; Yu, M | 1 |
| Baeten, JM; Bekker, LG; Celum, CL; Dallimore, J; Duyver, M; Gill, K; McConnell, M; Mendel, E; Morton, JF; Myers, L; Naidoo, K; Stein, G; Thomas, KK; van der Straten, A; Wiesner, L | 1 |
| Anderson, PL; Burke, LA; Bushman, L; Caffrey, M; Ellison, L; Ellsworth, GB; Gulick, RM; Liddle, D; Madhava, M; Mishra, S; O'Neal, C; Stein, J; Wells, MT | 1 |
| Amico, KR; Anderson, PL; Brown, E; Chakhtoura, N; Chi, BH; Hosek, S; Huang, S; Ibrahim, ME; Johnston, B; Kacanek, D; Korutaro, V; Lypen, K; Masenya, M; Nakabiito, C; Nematadzira, TG; Rooney, JF; Spiegel, HML; Stranix-Chibanda, L; Taulo, F; Wiesner, L; Yager, J | 1 |
| Anderson, PL; Bushman, LR; Castillo-Mancilla, JR; Coleman, SS; Coyle, RP; Ellison, L; Kiser, JJ; Libby, AM; MaWhinney, S; Morrow, M; Saderup, AM; Zheng, JH | 1 |
| Bekker, LG; Celum, CL; Duyver, M; Fynn, L; Gill, K; Giovenco, D; Morton, JF; O'Rourke, S; van der Straten, A | 1 |
| Anderson, PL; Ibrahim, M; MaWhinney, S; Moore, CM; Peterson, S | 1 |
| Adeyeye, A; Agyei, Y; Anderson, PL; Baeten, JM; Bekker, LG; Celum, C; Delany-Moretlwe, S; Donnell, DJ; Dye, BJ; Fogel, JM; Hosek, S; Kassim, S; Mgodi, N; Mukaka, S; Noble, H; Pathak, S; Rooney, J; Rose, SM; Tsholwana, M; Wiesner, L; Wilson, E; Yuha, K | 1 |
| Alessi, T; Feldman, PL; Felx, M; Jain, R; Roller, S; Shelton, J; Singh, R; Wang, Y; Yang, B; Zane, D | 1 |
| Anderson, PL; Bauer, R; Buschman, L; Charreau, I; Cotte, L; Cua, E; Delaugerre, C; Goldwirt, L; Laghzal, A; Liegeon, G; Meyer, L; Molina, JM; Mourah, S; Pialou, G | 1 |
| Alnouti, Y; Bade, AN; Cobb, DA; Cohen, SM; Deodhar, S; Edagwa, B; Gautam, N; Gendelman, HE; McMillan, J; Shetty, BLD; Smith, N | 1 |
| Abuogi, LL; Anderson, PL; Castillo-Mancilla, J; Hampanda, K; Helova, A; Odwar, T; Onono, M; Owuor, K; Turan, JM | 1 |
| Anderson, PL; Brijkumar, J; Bushman, LR; Castillo-Mancilla, JR; Edwards, JA; Ellison, L; Johnson, BA; Kuritzkes, DR; Lee, MH; Marconi, VC; Moodley, P; Moosa, MY; Ofotokun, I; Pillay, M; Pillay, S; Sunpath, H; Zhao, Y | 1 |
| Allerton, J; Castillo-Mancilla, J; Hsiao, NY; Hu, NC; Kabanda, S; Lesosky, M; Malaba, TR; Myer, L; Odayar, J; Orrell, C; Phillips, TK; Wiesner, L | 1 |
| Anderson, PL; Castillo-Mancilla, JR; Dolezal, C; Ferraris, C; Hsiao, NY; Jennings, L; Joska, J; Leu, CS; Mgbako, O; Myer, L; Nguyen, N; Orrell, C; Remien, RH; Robbins, RN | 1 |
| Anderson, PL; Bushman, LR; Castillo-Mancilla, JR; Coleman, SS; Coyle, RP; Ellison, L; Kiser, JJ; MaWhinney, S; Morrow, M; Zheng, JH | 1 |
| Liu, W; Yan, B; Yu, S | 1 |
| Anderson, PL; Bekker, LG; Celum, C; Chirenje, ZM; Delany-Moretlwe, S; Donnell, D; Hosek, S; Marzinke, MA; Mgodi, N; Velloza, J | 1 |
| Brady, M; Chen, YQ; Cover, J; Cressey, TR; Drain, P; Duerr, A; Kariithi, E; Mori, K; Obanda, R; Obong'o, C; Okomo, G; Oluoch-Madiang, D; Tapsoba, JD | 1 |
1 review(s) available for adenine and tenofovir diphosphate
| Article | Year |
|---|---|
Approaches to Objectively Measure Antiretroviral Medication Adherence and Drive Adherence Interventions.
Topics: Adenine; Adult; Anti-HIV Agents; Emtricitabine; Female; Hair; HIV Infections; Humans; Leukocytes, Mononuclear; Male; Medication Adherence; Monitoring, Ambulatory; Organophosphates; Pre-Exposure Prophylaxis; Tenofovir; Viral Load | 2020 |
22 trial(s) available for adenine and tenofovir diphosphate
| Article | Year |
|---|---|
Antiviral activity, safety, and pharmacokinetics/pharmacodynamics of tenofovir alafenamide as 10-day monotherapy in HIV-1-positive adults.
Topics: Adenine; Adult; Alanine; Anti-Retroviral Agents; Area Under Curve; Dose-Response Relationship, Drug; Fatigue; Female; HIV Infections; HIV-1; Humans; Male; Middle Aged; Nausea; Organophosphates; Organophosphonates; RNA, Viral; Single-Blind Method; Statistics, Nonparametric; Tenofovir; Viral Load; Young Adult | 2013 |
Population pharmacokinetics of tenofovir and tenofovir-diphosphate in healthy women.
Topics: Adenine; Administration, Oral; Adolescent; Adult; Antiviral Agents; Biological Availability; Cross-Over Studies; Female; Half-Life; Healthy Volunteers; Humans; Leukocytes, Mononuclear; Middle Aged; Organophosphates; Tenofovir; Vagina; Vaginal Creams, Foams, and Jellies; Women; Young Adult | 2015 |
Plasma Tenofovir, Emtricitabine, and Rilpivirine and Intracellular Tenofovir Diphosphate and Emtricitabine Triphosphate Pharmacokinetics following Drug Intake Cessation.
Topics: Adenine; Adolescent; Adult; Aged; Anti-HIV Agents; Emtricitabine; Female; HIV Infections; Humans; Middle Aged; Organophosphates; Rilpivirine; Tenofovir; Young Adult | 2015 |
Single-dose pharmacokinetics of tenofovir alafenamide and its active metabolite in the mucosal tissues.
Topics: Adenine; Adult; Alanine; Cervix Uteri; Drug Administration Schedule; Epithelial Cells; Female; Gastrointestinal Tract; Humans; Intestinal Mucosa; Leukocytes, Mononuclear; Middle Aged; Mucous Membrane; Organophosphates; Pre-Exposure Prophylaxis; Rectum; Tenofovir; Tissue Distribution; Vagina; Young Adult | 2017 |
Intracellular Tenofovir-Diphosphate and Emtricitabine-Triphosphate in Dried Blood Spots following Directly Observed Therapy.
Topics: Adenine; Adult; Anti-HIV Agents; Cross-Over Studies; Directly Observed Therapy; Dried Blood Spot Testing; Emtricitabine; Female; HIV Infections; Humans; Male; Middle Aged; Organophosphates; Patient Compliance; Pre-Exposure Prophylaxis; Prospective Studies; Sexual and Gender Minorities; Young Adult | 2018 |
Randomized Controlled Trial of Daily Text Messages to Support Adherence to Preexposure Prophylaxis in Individuals at Risk for Human Immunodeficiency Virus: The TAPIR Study.
Topics: Adenine; Adult; Anti-HIV Agents; HIV Infections; Humans; Male; Medication Adherence; Organophosphates; Pre-Exposure Prophylaxis; Text Messaging; Transgender Persons | 2018 |
Effects of sofosbuvir-based hepatitis C treatment on the pharmacokinetics of tenofovir in HIV/HCV-coinfected individuals receiving tenofovir disoproxil fumarate.
Topics: Adenine; Adult; Antiviral Agents; Benzimidazoles; Coinfection; Drug Interactions; Fluorenes; Hepatitis C; HIV Infections; Humans; Male; Middle Aged; Organophosphates; Ribavirin; Sofosbuvir; Tenofovir; Uridine Monophosphate | 2018 |
Pharmacokinetics and Pharmacodynamics of Tenofovir Reduced-Glycerin 1% Gel in the Rectal and Vaginal Compartments in Women: A Cross-Compartmental Study With Directly Observed Dosing.
Topics: Adenine; Administration, Rectal; Adult; Anti-HIV Agents; Body Fluids; Dose-Response Relationship, Drug; Female; Gels; Glycerol; HIV Infections; Humans; Middle Aged; Organophosphates; Pre-Exposure Prophylaxis; Rectum; Tenofovir; Treatment Outcome; Vagina; Vaginal Creams, Foams, and Jellies; Virus Replication; Young Adult | 2018 |
MALDI Mass Spectrometry Imaging Reveals Heterogeneous Distribution of Tenofovir and Tenofovir Diphosphate in Colorectal Tissue of Subjects Receiving a Tenofovir-Containing Enema.
Topics: Adenine; Colon; Enema; HIV Infections; Humans; Molecular Imaging; Organophosphates; Rectum; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tenofovir | 2018 |
Rifampicin effect on intracellular and plasma pharmacokinetics of tenofovir alafenamide.
Topics: Adenine; Adult; Anti-HIV Agents; Antibiotics, Antitubercular; Antiviral Agents; Drug Interactions; Drug Resistance, Viral; Female; Humans; Male; Middle Aged; Organophosphates; Pharmacogenomic Testing; Rifampin; Tissue Distribution; Young Adult | 2019 |
Predictors of Long-Term HIV Pre-exposure Prophylaxis Adherence After Study Participation in Men Who Have Sex With Men.
Topics: Adenine; Adult; Follow-Up Studies; HIV Infections; Homosexuality, Male; Humans; Logistic Models; Male; Medication Adherence; Middle Aged; Organophosphates; Pre-Exposure Prophylaxis; Regression Analysis; Risk-Taking; Sexual and Gender Minorities | 2019 |
Pharmacokinetics of tenofovir monoester and association with intracellular tenofovir diphosphate following single-dose tenofovir disoproxil fumarate.
Topics: Adenine; Adult; Anti-HIV Agents; Blood Chemical Analysis; Cross-Over Studies; Emtricitabine; Female; HIV Infections; Humans; Male; Organophosphates; Phosphorous Acids | 2019 |
Vaginal microbiota and mucosal pharmacokinetics of tenofovir in healthy women using tenofovir and tenofovir/levonorgestrel vaginal rings.
Topics: Adenine; Adult; Anti-HIV Agents; Antiviral Agents; Contraceptive Agents, Hormonal; Contraceptive Devices, Female; Device Removal; Female; Herpes Genitalis; HIV Infections; Humans; Levonorgestrel; Microbiota; Middle Aged; Mucous Membrane; Organophosphates; Tenofovir; Vagina; Young Adult | 2019 |
Antenatal Intracellular Concentrations of Tenofovir Diphosphate and Emtricitabine Triphosphate and Associations Between Tenofovir Diphosphate and Severe Adverse Pregnancy Outcomes: IMPAACT-PROMISE (1077BF) Trial.
Topics: Adenine; Anti-HIV Agents; Case-Control Studies; Chromatography, Liquid; Drug Combinations; Emtricitabine; Female; HIV Infections; Humans; Logistic Models; Lopinavir; Medication Adherence; Organophosphates; Polyphosphates; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Retrospective Studies; Ritonavir; Tenofovir | 2020 |
Intracellular Tenofovir-Diphosphate and Emtricitabine-Triphosphate in Dried Blood Spots Following Tenofovir Alafenamide: The TAF-DBS Study.
Topics: Adenine; Adolescent; Adult; Alanine; Anti-HIV Agents; Cross-Over Studies; Drug Combinations; Emtricitabine; Female; HIV Infections; Humans; Male; Medication Adherence; Middle Aged; Organophosphates; Polyphosphates; Pre-Exposure Prophylaxis; Prospective Studies; Tenofovir; Young Adult | 2020 |
Sex Hormone Therapy and Tenofovir Diphosphate Concentration in Dried Blood Spots: Primary Results of the Interactions Between Antiretrovirals And Transgender Hormones Study.
Topics: Adenine; Anti-HIV Agents; Emtricitabine; Estradiol; Female; HIV Infections; Humans; Male; Organophosphates; Pre-Exposure Prophylaxis; Transgender Persons | 2021 |
Incentives conditioned on tenofovir levels to support PrEP adherence among young South African women: a randomized trial.
Topics: Adenine; Adolescent; Adult; Anti-HIV Agents; Black People; Female; HIV Infections; Humans; Incidence; Medication Adherence; Motivation; Organophosphates; Pre-Exposure Prophylaxis; South Africa; Young Adult | 2020 |
Randomized Pilot Study of an Advanced Smart-Pill Bottle as an Adherence Intervention in Patients With HIV on Antiretroviral Treatment.
Topics: Adenine; Adult; Anti-HIV Agents; Anti-Retroviral Agents; Female; HIV Infections; Humans; Male; Middle Aged; Organophosphates; Pilot Projects; Tenofovir | 2021 |
Tenofovir Diphosphate Concentrations in Dried Blood Spots From Pregnant and Postpartum Adolescent and Young Women Receiving Daily Observed Pre-exposure Prophylaxis in Sub-Saharan Africa.
Topics: Adenine; Adolescent; Africa South of the Sahara; Anti-HIV Agents; Female; HIV Infections; Humans; Medication Adherence; Organophosphates; Postpartum Period; Pre-Exposure Prophylaxis; Pregnancy; Young Adult | 2021 |
PrEP uptake, persistence, adherence, and effect of retrospective drug level feedback on PrEP adherence among young women in southern Africa: Results from HPTN 082, a randomized controlled trial.
Topics: Adenine; Adolescent; Adult; Anti-HIV Agents; Counseling; Dried Blood Spot Testing; Drug Monitoring; Feedback, Psychological; Female; Health Knowledge, Attitudes, Practice; HIV Infections; Humans; Medication Adherence; Organophosphates; Pre-Exposure Prophylaxis; Sex Factors; South Africa; Text Messaging; Time Factors; Treatment Outcome; Young Adult; Zimbabwe | 2021 |
Estimated pill intake with on-demand PrEP with oral TDF/FTC using TFV-DP concentration in dried blood spots in the ANRS IPERGAY trial.
Topics: Adenine; Adult; Anti-HIV Agents; Emtricitabine; Female; HIV Infections; Homosexuality, Male; Humans; Male; Medication Adherence; Organophosphates; Pre-Exposure Prophylaxis; Sexual and Gender Minorities; Tenofovir | 2021 |
Alignment of PrEP adherence with periods of HIV risk among adolescent girls and young women in South Africa and Zimbabwe: a secondary analysis of the HPTN 082 randomised controlled trial.
Topics: Adenine; Adolescent; Adult; Anti-HIV Agents; Female; HIV Infections; Humans; Medication Adherence; Organophosphates; Pre-Exposure Prophylaxis; South Africa; Tenofovir; Young Adult; Zimbabwe | 2022 |
48 other study(ies) available for adenine and tenofovir diphosphate
| Article | Year |
|---|---|
Multicompartmental pharmacokinetic model of tenofovir delivery by a vaginal gel.
Topics: Adenine; Anti-HIV Agents; Area Under Curve; Epithelium; Female; HIV Infections; Humans; Models, Statistical; Mucous Membrane; Organophosphates; Organophosphonates; Tenofovir; Vagina; Vaginal Creams, Foams, and Jellies | 2013 |
Tenofovir diphosphate concentrations and prophylactic effect in a macaque model of rectal simian HIV transmission.
Topics: Adenine; Animals; Anti-HIV Agents; Disease Models, Animal; Disease Transmission, Infectious; HIV Infections; Humans; Leukocytes, Mononuclear; Macaca; Male; Organophosphates; Pre-Exposure Prophylaxis; Treatment Outcome | 2014 |
Sex hormones regulate tenofovir-diphosphate in female reproductive tract cells in culture.
Topics: Adenine; Adult; Aged; Anti-HIV Agents; Biological Transport; CD4-Positive T-Lymphocytes; Cervix Uteri; Endometrium; Epithelial Cells; Estradiol; Female; Fibroblasts; Humans; Macrophages; Middle Aged; Organ Specificity; Organophosphates; Primary Cell Culture; Progesterone | 2014 |
Short communication: Tenofovir diphosphate in dried blood spots as an objective measure of adherence in HIV-infected women.
Topics: Adenine; Adult; Aged; Anti-HIV Agents; Blood Chemical Analysis; Chromatography, Liquid; Desiccation; Female; HIV Infections; Humans; Medication Adherence; Middle Aged; Organophosphates; Specimen Handling; Tandem Mass Spectrometry | 2015 |
Implications of efficient hepatic delivery by tenofovir alafenamide (GS-7340) for hepatitis B virus therapy.
Topics: Adenine; Alanine; Animals; Cells, Cultured; Dogs; Hepatitis B virus; Hepatocytes; Humans; Liver; Male; Organophosphates; Tenofovir | 2015 |
Impact of protease inhibitors on intracellular concentration of tenofovir-diphosphate among HIV-1 infected patients.
Topics: Adenine; Adult; Anti-HIV Agents; Cross-Sectional Studies; Cytosol; Drug Interactions; Female; HIV Infections; HIV Protease Inhibitors; Humans; Leukocytes, Mononuclear; Male; Middle Aged; Organophosphates | 2015 |
Preexposure Prophylaxis for HIV Infection Integrated With Municipal- and Community-Based Sexual Health Services.
Topics: Adenine; Adolescent; Adult; Anti-HIV Agents; Bisexuality; Chlamydia Infections; Community Health Services; District of Columbia; Female; Florida; Gonorrhea; HIV Infections; Homosexuality, Male; Humans; Male; Medication Adherence; Middle Aged; Organophosphates; Pre-Exposure Prophylaxis; Prospective Studies; Reproductive Health; San Francisco; Sexual Behavior; Syphilis; Tenofovir; Transgender Persons; Unsafe Sex; Young Adult | 2016 |
Application of an intracellular assay for determination of tenofovir-diphosphate and emtricitabine-triphosphate from erythrocytes using dried blood spots.
Topics: Adenine; Biological Assay; Dried Blood Spot Testing; Emtricitabine; Erythrocytes; Hematocrit; HIV Infections; Humans; Medication Adherence; Methanol; Organophosphates; Polyphosphates; Reproducibility of Results; Solutions; Temperature; Water | 2016 |
Infrequent development of drug resistance in HIV-1-infected treatment-naive subjects after 96 weeks of treatment with elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide or elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil fumarate.
Topics: Adenine; Amino Acid Substitution; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cobicistat; Drug Resistance, Viral; Emtricitabine; Genotype; HIV Infections; HIV-1; Humans; Microbial Sensitivity Tests; Mutation; Organophosphates; Phenotype; Tenofovir | 2017 |
Simultaneous determination of tenofovir alafenamide and its active metabolites tenofovir and tenofovir diphosphate in HBV-infected hepatocyte with a sensitive LC-MS/MS method.
Topics: Adenine; Alanine; Anti-HIV Agents; Cell Line, Tumor; Chromatography, Liquid; DNA Replication; Half-Life; Hep G2 Cells; Hepatocytes; HIV Infections; HIV-1; Humans; Organophosphates; Prodrugs; Tandem Mass Spectrometry; Tenofovir; Virus Replication | 2017 |
Acquisition of wild-type HIV-1 infection in a patient on pre-exposure prophylaxis with high intracellular concentrations of tenofovir diphosphate: a case report.
Topics: Adenine; Anti-HIV Agents; Emtricitabine; HIV Infections; HIV Seropositivity; HIV-1; Homosexuality, Male; Humans; Lymphogranuloma Venereum; Male; Medication Adherence; Middle Aged; Organophosphates; Pre-Exposure Prophylaxis; RNA, Viral; Tenofovir; Transgender Persons; Urinary Tract Infections | 2017 |
The role of menopause in tenofovir diphosphate and emtricitabine triphosphate concentrations in cervical tissue.
Topics: Adenine; Adult; Aged; Anti-HIV Agents; Cervix Uteri; Chromatography, Liquid; Emtricitabine; Female; Humans; Menopause; Middle Aged; Organophosphates; Tandem Mass Spectrometry; Young Adult | 2018 |
Hormonal Contraceptives Differentially Suppress TFV and TAF Inhibition of HIV Infection and TFV-DP in Blood and Genital Tract CD4+ T cells.
Topics: Adenine; Adult; Alanine; Anti-HIV Agents; Anti-Retroviral Agents; CD4-Positive T-Lymphocytes; Cells, Cultured; Contraceptive Agents; Contraceptives, Oral, Hormonal; Female; Genitalia, Female; HIV Infections; HIV-1; Humans; Middle Aged; Organophosphates; Progestins; Tenofovir | 2017 |
Short Communication: Specimen Processing Impacts Tissue Tenofovir Pharmacokinetic Measurements.
Topics: Adenine; Administration, Oral; Anti-HIV Agents; Biopsy; Culture Media; HIV Infections; Humans; Male; Organophosphates; Pre-Exposure Prophylaxis; Rectum; Specimen Handling; Tenofovir | 2018 |
Establishment of intracellular tenofovir-diphosphate as the key determinant for in vitro-in vivo translation of antiviral efficacy.
Topics: Adenine; Alanine; Anti-HIV Agents; Cytoplasm; Databases, Factual; Dose-Response Relationship, Drug; HIV Infections; HIV-1; Humans; Leukocytes, Mononuclear; Meta-Analysis as Topic; Organophosphates; Prodrugs; Tenofovir; Viral Load; Virus Replication | 2018 |
Differences in Local and Systemic TFV PK Among Premenopausal Versus Postmenopausal Women Exposed to TFV 1% Vaginal Gel.
Topics: Adenine; Administration, Intravaginal; Administration, Topical; Anti-HIV Agents; Epithelium; Estradiol; Female; HIV; HIV Infections; Humans; Menstrual Cycle; Mucous Membrane; Organophosphates; Postmenopause; Premenopause; Tenofovir; Time Factors; Vagina; Vaginal Creams, Foams, and Jellies | 2018 |
Development of rectal enema as microbicide (DREAM): Preclinical progressive selection of a tenofovir prodrug enema.
Topics: Adenine; Administration, Rectal; Alanine; Animals; Anti-HIV Agents; Anti-Infective Agents; Enema; HIV Infections; HIV-1; Homosexuality, Male; Male; Mice; Organophosphates; Organophosphonates; Pre-Exposure Prophylaxis; Prodrugs; Rectum; Sexual and Gender Minorities; Tenofovir | 2019 |
Tenofovir and tenofovir-diphosphate concentrations during pregnancy among HIV-uninfected women using oral preexposure prophylaxis.
Topics: Adenine; Administration, Oral; Adult; Anti-HIV Agents; Blood Chemical Analysis; Chemoprevention; Female; HIV Infections; Humans; Middle Aged; Organophosphates; Pre-Exposure Prophylaxis; Pregnancy; Pregnancy Complications, Infectious; Young Adult | 2018 |
Transcutaneously refillable nanofluidic implant achieves sustained level of tenofovir diphosphate for HIV pre-exposure prophylaxis.
Topics: Adenine; Administration, Cutaneous; Animals; Antiviral Agents; Drug Delivery Systems; Emtricitabine; Equipment Design; HIV Infections; Humans; Infusion Pumps, Implantable; Lab-On-A-Chip Devices; Macaca mulatta; Organophosphates; Pre-Exposure Prophylaxis | 2018 |
Tenofovir Diphosphate in Dried Blood Spots Is Strongly Associated With Viral Suppression in Individuals With Human Immunodeficiency Virus Infections.
Topics: Adenine; Adult; Antiviral Agents; Dried Blood Spot Testing; Female; HIV Infections; Humans; Male; Middle Aged; Organophosphates; Prospective Studies; Viral Load | 2019 |
Brief Report: Role of Sociobehavioral Factors in Subprotective TFV-DP Levels Among YMSM Enrolled in 2 PrEP Trials.
Topics: Adenine; Adolescent; Anti-HIV Agents; Health Surveys; HIV Infections; Homosexuality, Male; Humans; Male; Medication Adherence; Organophosphates; Patient Acceptance of Health Care; Pre-Exposure Prophylaxis; Risk-Taking; Young Adult | 2019 |
Epithelial Cells and Fibroblasts from the Human Female Reproductive Tract Accumulate and Release TFV and TAF to Sustain Inhibition of HIV Infection of CD4+ T cells.
Topics: Adenine; Adult; Alanine; Anti-HIV Agents; CD4-Positive T-Lymphocytes; Cervix Uteri; Drug Resistance, Multiple; Endometrium; Epithelial Cells; Female; Fibroblasts; Genitalia, Female; HIV Infections; Humans; Middle Aged; Organophosphates; Tenofovir; Vagina | 2019 |
Engagement in Mental Health Care is Associated with Higher Cumulative Drug Exposure and Adherence to Antiretroviral Therapy.
Topics: Adenine; Adult; Anti-HIV Agents; Biomarkers; Chromatography, Liquid; Comorbidity; Female; HIV Infections; Humans; Male; Medication Adherence; Mental Disorders; Mental Health; Mental Health Services; Middle Aged; Organophosphates; Tandem Mass Spectrometry; Viral Load | 2019 |
A Comparison of Plasma Efavirenz and Tenofovir, Dried Blood Spot Tenofovir-Diphosphate, and Self-Reported Adherence to Predict Virologic Suppression Among South African Women.
Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Anti-Retroviral Agents; Benzoxazines; Cross-Sectional Studies; Cyclopropanes; Emtricitabine; Female; HIV Infections; Humans; Logistic Models; Organophosphates; Plasma; Self Report; South Africa; Tenofovir | 2019 |
Effective use of pre-exposure prophylaxis (PrEP) Among stimulant users with multiple condomless sex partners: a longitudinal study of men who have sex with men in Los Angeles.
Topics: Adenine; Adult; Anti-Retroviral Agents; Central Nervous System Stimulants; Condoms; HIV Infections; Homosexuality, Male; Humans; Longitudinal Studies; Los Angeles; Male; Medication Adherence; Organophosphates; Pre-Exposure Prophylaxis; Sexual Partners; Tenofovir; Unsafe Sex | 2019 |
Predictive Value of Tenofovir Diphosphate in Dried Blood Spots for Future Viremia in Persons Living With HIV.
Topics: Adenine; Adult; Anti-HIV Agents; Biomarkers; Female; HIV; HIV Infections; Humans; Male; Medication Adherence; Middle Aged; Organophosphates; Predictive Value of Tests; Tenofovir; Viral Load; Viremia | 2019 |
Decreased Tenofovir Diphosphate Concentrations in a Transgender Female Cohort: Implications for Human Immunodeficiency Virus Preexposure Prophylaxis.
Topics: Adenine; Adolescent; Adult; Aged; Anti-HIV Agents; Drug Monitoring; Female; HIV; HIV Infections; Humans; Middle Aged; Organophosphates; Pre-Exposure Prophylaxis; Tissue Distribution; Transgender Persons; Treatment Outcome; Young Adult | 2019 |
Adherence to PrEP Among Young Men Who Have Sex With Men Participating in a Sexual Health Services Demonstration Project in Alameda County, California.
Topics: Adenine; Adolescent; Adult; Black or African American; California; Emtricitabine; HIV Infections; Homosexuality, Male; Humans; Male; Medication Adherence; Organophosphates; Pre-Exposure Prophylaxis; Sexual Behavior; Sexual Health; Young Adult | 2019 |
Brief Report: Short-Term Adherence Marker to PrEP Predicts Future Nonretention in a Large PrEP Demo Project: Implications for Point-of-Care Adherence Testing.
Topics: Adenine; Adult; Anti-HIV Agents; Dried Blood Spot Testing; Emtricitabine; Female; HIV Infections; Homosexuality, Male; Humans; Male; Medication Adherence; Organophosphates; Point-of-Care Testing; Pre-Exposure Prophylaxis; Proportional Hazards Models; Prospective Studies; Tenofovir | 2019 |
Depot Medroxyprogesterone Acetate and the Vaginal Microbiome as Modifiers of Tenofovir Diphosphate and Lamivudine Triphosphate Concentrations in the Female Genital Tract of Ugandan Women: Implications for Tenofovir Disoproxil Fumarate/Lamivudine in Preexp
Topics: Adenine; Anti-HIV Agents; Cytidine Triphosphate; Dideoxynucleotides; Emtricitabine; Female; HIV Infections; Humans; Lamivudine; Medroxyprogesterone Acetate; Microbiota; Organophosphates; Pre-Exposure Prophylaxis; Tenofovir; Uganda | 2020 |
Tenofovir Plasma Concentration from Preexposure Prophylaxis at the Time of Potential HIV Exposure: a Population Pharmacokinetic Modeling and Simulation Study Involving Serodiscordant Couples in East Africa.
Topics: Adenine; Anti-HIV Agents; Bayes Theorem; Cross-Over Studies; Female; HIV; HIV Infections; Humans; Kenya; Leukocytes, Mononuclear; Male; Organophosphates; Pre-Exposure Prophylaxis; Prospective Studies; Sexual Partners; Tenofovir; Uganda | 2019 |
The determination of human peripheral blood mononuclear cell counts using a genomic DNA standard and application in tenofovir diphosphate quantitation.
Topics: Adenine; Alanine; Cell Count; Chromatography, High Pressure Liquid; DNA; Fluorescent Dyes; Genomics; Humans; Image Cytometry; Intercalating Agents; Leukocytes, Mononuclear; Organophosphates; Prodrugs; Tandem Mass Spectrometry; Tenofovir | 2019 |
Octadecyloxyethyl benzyl tenofovir: A novel tenofovir diester provides sustained intracellular levels of tenofovir diphosphate.
Topics: Adenine; Chemistry Techniques, Synthetic; Esters; Humans; Molecular Structure; Organophosphates; Tenofovir; Tissue Distribution | 2019 |
Direct quantitation of tenofovir diphosphate in human blood with mass spectrometry for adherence monitoring.
Topics: Adenine; Anti-HIV Agents; Chromatography, Liquid; Humans; Organophosphates; Proof of Concept Study; Reference Standards; Tandem Mass Spectrometry | 2020 |
Factors associated with tenofovir diphosphate concentrations in dried blood spots in persons living with HIV.
Topics: Adenine; Adolescent; Anti-HIV Agents; Female; HIV Infections; Humans; Male; Organophosphates; Tenofovir | 2020 |
Immunoassay for HIV Drug Metabolites Tenofovir and Tenofovir Diphosphate.
Topics: Adenine; Anti-HIV Agents; HIV Infections; Humans; Immunoassay; Medication Adherence; Organophosphates; Pharmaceutical Preparations; Tenofovir | 2020 |
Higher medication complexity in persons with HIV is associated with lower tenofovir diphosphate in dried blood spots.
Topics: Adenine; Dried Blood Spot Testing; HIV Infections; Humans; Organophosphates; Prospective Studies | 2021 |
Experiences of oral pre-exposure prophylaxis (PrEP) use disclosure among South African adolescent girls and young women and its perceived impact on adherence.
Topics: Adenine; Adolescent; Adult; Africa; Anti-HIV Agents; Black People; Female; HIV Infections; Humans; Interview, Psychological; Medication Adherence; Organophosphates; Pre-Exposure Prophylaxis; Safe Sex; Sexual Behavior; Social Stigma; Young Adult | 2021 |
A comparison of covariate selection techniques applied to pre-exposure prophylaxis (PrEP) drug concentration data in men and transgender women at risk for HIV.
Topics: Adenine; Adult; Anti-HIV Agents; Female; HIV Infections; Humans; Male; Medication Adherence; Organophosphates; Pre-Exposure Prophylaxis; Tenofovir; Transgender Persons | 2021 |
A 28-Day Toxicity Study of Tenofovir Alafenamide Hemifumarate by Subcutaneous Infusion in Rats and Dogs.
Topics: Adenine; Alanine; Animals; Anti-HIV Agents; Dogs; Edema; HIV Infections; HIV-1; Infusions, Subcutaneous; Male; Organophosphates; Pre-Exposure Prophylaxis; Rats; Tenofovir | 2021 |
Transformation of tenofovir into stable ProTide nanocrystals with long-acting pharmacokinetic profiles.
Topics: Adenine; Alanine; Animals; Anti-HIV Agents; Drug Stability; Female; HIV Infections; HIV-1; Humans; Male; Nanoparticles; Organophosphates; Prodrugs; Rats, Sprague-Dawley; Tenofovir; Therapeutic Equivalency | 2021 |
Tenofovir Diphosphate in Dried Blood Spots in Pregnant and Postpartum Women With HIV in Kenya: A Novel Approach to Measuring Peripartum Adherence.
Topics: Adenine; Anti-HIV Agents; Female; HIV Infections; Humans; Kenya; Medication Adherence; Organophosphates; Peripartum Period; Postpartum Period; Pregnancy | 2022 |
Tenofovir diphosphate levels in dried blood spots are associated with virologic failure and resistance to first-line therapy in South Africa: a case-control cohort study.
Topics: Adenine; Adult; Anti-HIV Agents; Case-Control Studies; Female; HIV Infections; Humans; Organophosphates; Prospective Studies; South Africa | 2021 |
Use of Tenofovir Diphosphate Levels to Predict Viremia During the Postpartum Period in Women Living With Human Immunodeficiency Virus (HIV): A Nested Case-Control Study.
Topics: Adenine; Anti-HIV Agents; Case-Control Studies; Female; HIV; HIV Infections; Humans; Organophosphates; Postpartum Period; Pregnancy; Tenofovir; Viremia | 2022 |
Tenofovir diphosphate in dried blood spots predicts future viremia in persons with HIV taking antiretroviral therapy in South Africa.
Topics: Adenine; Adult; Anti-HIV Agents; Biomarkers; Female; HIV Infections; Humans; Male; Medication Adherence; Organophosphates; South Africa; Viremia | 2022 |
Cumulative tenofovir diphosphate exposure in persons with HIV taking single- vs. multiple-tablet regimens.
Topics: Adenine; Anti-HIV Agents; HIV Infections; Humans; Organophosphates; Tablets; Tenofovir | 2022 |
Effect of alcohol exposure on the efficacy and safety of tenofovir alafenamide fumarate, a major medicine against human immunodeficiency virus.
Topics: Adenine; Alanine; Alcohol Drinking; Anti-HIV Agents; Carboxylic Ester Hydrolases; Chromatography, Liquid; Ethanol; Fumarates; HIV; HIV Infections; Humans; Lipids; Organophosphates; Tandem Mass Spectrometry; Tenofovir | 2022 |
Continued attendance in a PrEP program despite low adherence and non-protective drug levels among adolescent girls and young women in Kenya: Results from a prospective cohort study.
Topics: Adenine; Adolescent; Adult; Anti-HIV Agents; Child; Contraceptive Agents; Diphosphates; Emtricitabine; Female; HIV Infections; Humans; Infant; Kenya; Male; Medication Adherence; Organophosphates; Pre-Exposure Prophylaxis; Prospective Studies; Tenofovir; Young Adult | 2022 |