Compounds > adenine

adenine and rolipram

adenine has been researched along with rolipram in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19902 (10.53)18.7374
1990's5 (26.32)18.2507
2000's8 (42.11)29.6817
2010's2 (10.53)24.3611
2020's2 (10.53)2.80

Authors

AuthorsStudies
Donaldson, J; Hall, IP; Hill, SJ1
Fredholm, BB; Lerner, UH; Sahlberg, K1
Kendall, DA; Wilson, VG; Wright, IK1
Barnard, JW; Prasad, VR; Seibert, AF; Smart, DA; Strada, SJ; Taylor, AE; Thompson, WJ1
Harnett, MM; Houslay, MD; Lobban, M; Michie, AM; Müller, T1
Wise, H1
Eisenbrand, G; Fürstenberger, G; Marko, D; Romanakis, K; Steinbauer, B; Zankl, H1
Brading, AF; Jones, OM; McC Mortensen, NJ1
O'Donnell, JM; Suvarna, NU1
Bobalova, J; Mutafova-Yambolieva, VN; Smyth, L1
Hernández, J; Juan-Fita, MJ; Vargas, ML1
Andersson, TP; Sköld, HN; Svensson, SP1
Cicala, C; Cirino, G; Morello, S; Severino, B; Sorrentino, L; Vellecco, V1
Cao, Q; Ding, YH; Ellenberger, T; Iffland, A; Kamath, AV; Kohls, D; Kothe, M; Low, S; Luan, J; Zhang, Y1
Janciauskiene, SM; Nita, IM; Stevens, T1
Adderley, SP; Bowles, EA; Ellsworth, ML; Sprague, RS; Sridharan, M; Stephenson, AH1
Arai, N; Hiramoto, K; Inui, M; Manganiello, VC; Morita, H; Murata, T; Shimizu, K; Tagawa, T1
Alvarez, DF; Annamdevula, N; Audia, JP; Britain, A; Dunbar, G; Hardy, KS; Housley, N; Leavesley, S; Renema, P; Rich, T; Spadafora, D1
Gergs, U; Laufs, U; Neumann, J; Voss, R; Werner, C1

Other Studies

19 other study(ies) available for adenine and rolipram

ArticleYear
Inhibition of histamine-stimulated inositol phospholipid hydrolysis by agents which increase cyclic AMP levels in bovine tracheal smooth muscle.
    British journal of pharmacology, 1989, Volume: 97, Issue:2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenine; Albuterol; Animals; Bucladesine; Cattle; Colforsin; Cyclic AMP; Histamine; Histamine Antagonists; Hydrolysis; In Vitro Techniques; Inositol Phosphates; Muscle, Smooth; Phosphodiesterase Inhibitors; Pyrrolidinones; Rolipram; Sugar Phosphates; Trachea; Vasoactive Intestinal Peptide

1989
Characterization of adenosine receptors in bone. Studies on the effect of adenosine analogues on cyclic AMP formation and bone resorption in cultured mouse calvaria.
    Acta physiologica Scandinavica, 1987, Volume: 131, Issue:2

    Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Bone and Bones; Bone Resorption; Cells, Cultured; Colforsin; Cyclic AMP; Mice; Phenylisopropyladenosine; Pyrrolidinones; Receptors, Cyclic AMP; Rolipram; Theophylline

1987
Alpha 2-adrenoceptor mediated inhibition of forskolin-stimulated cyclic AMP accumulation in isolated porcine palmar lateral veins.
    Naunyn-Schmiedeberg's archives of pharmacology, 1995, Volume: 352, Issue:2

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Colforsin; Cyclic AMP; Enzyme Inhibitors; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Prazosin; Pyrrolidinones; Receptors, Adrenergic, alpha-2; Rolipram; Swine; Veins; Yohimbine

1995
Reversal of pulmonary capillary ischemia-reperfusion injury by rolipram, a cAMP phosphodiesterase inhibitor.
    Journal of applied physiology (Bethesda, Md. : 1985), 1994, Volume: 77, Issue:2

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Adenylyl Cyclases; Animals; Capillary Permeability; Colforsin; Image Processing, Computer-Assisted; Isoproterenol; Lung; Male; Pulmonary Circulation; Pyrrolidinones; Rats; Rats, Inbred Strains; Reperfusion Injury; Rolipram

1994
Rapid regulation of PDE-2 and PDE-4 cyclic AMP phosphodiesterase activity following ligation of the T cell antigen receptor on thymocytes: analysis using the selective inhibitors erythro-9-(2-hydroxy-3-nonyl)-adenine (EHNA) and rolipram.
    Cellular signalling, 1996, Volume: 8, Issue:2

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Animals; Antibodies, Monoclonal; Binding, Competitive; CD3 Complex; Cells, Cultured; Chromatography, High Pressure Liquid; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 1; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanosine Monophosphate; Humans; Isoenzymes; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Phosphodiesterase Inhibitors; Phytohemagglutinins; Pyrrolidinones; Rabbits; Receptors, Antigen, T-Cell; Rolipram; Sensitivity and Specificity; Signal Transduction; Thymus Gland

1996
The inhibitory effect of prostaglandin E2 on rat neutrophil aggregation.
    Journal of leukocyte biology, 1996, Volume: 60, Issue:4

    Topics: Adenine; Androstadienes; Animals; Ascitic Fluid; Cell Aggregation; Cells, Cultured; Chemotaxis, Leukocyte; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Enzyme Inhibitors; Glyburide; Isoquinolines; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphodiesterase Inhibitors; Phosphotransferases (Alcohol Group Acceptor); Potassium Channels; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Rolipram; Sulfonamides; Wortmannin

1996
Induction of apoptosis by an inhibitor of cAMP-specific PDE in malignant murine carcinoma cells overexpressing PDE activity in comparison to their nonmalignant counterparts.
    Cell biochemistry and biophysics, 1998, Volume: 28, Issue:2-3

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Animals; Carcinoma; Cell Cycle; Cell Division; Cell Size; Cell Transformation, Neoplastic; Cells, Cultured; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; DNA Fragmentation; Isoenzymes; Keratinocytes; Mice; Papilloma; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piperazines; Pteridines; Pyrrolidinones; Rolipram; Skin Neoplasms; Tumor Cells, Cultured

1998
Phosphodiesterase inhibitors cause relaxation of the internal anal sphincter in vitro.
    Diseases of the colon and rectum, 2002, Volume: 45, Issue:4

    Topics: Adenine; Aged; Aged, 80 and over; Anal Canal; Dipyridamole; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Isoquinolines; Male; Middle Aged; Muscle Relaxation; Muscle, Smooth; Phosphodiesterase Inhibitors; Platelet Aggregation Inhibitors; Purinones; Rectum; Rolipram; Tetrahydroisoquinolines; Vinca Alkaloids

2002
Hydrolysis of N-methyl-D-aspartate receptor-stimulated cAMP and cGMP by PDE4 and PDE2 phosphodiesterases in primary neuronal cultures of rat cerebral cortex and hippocampus.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 302, Issue:1

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Adenosine; Animals; Cells, Cultured; Cerebral Cortex; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 2; Cyclic Nucleotide Phosphodiesterases, Type 4; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Guanylate Cyclase; Hippocampus; N-Methylaspartate; Neurons; Nitric Oxide Donors; Nitric Oxide Synthase; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Rolipram

2002
Involvement of cyclic AMP-mediated pathway in neural release of noradrenaline in canine isolated mesenteric artery and vein.
    Cardiovascular research, 2003, Volume: 57, Issue:1

    Topics: Adenine; Adenylyl Cyclase Inhibitors; Animals; Autonomic Nervous System; Bucladesine; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dogs; Edetic Acid; Electric Stimulation; Isoproterenol; Mesenteric Arteries; Mesenteric Veins; Milrinone; Norepinephrine; Phosphodiesterase Inhibitors; Propranolol; Rolipram; Second Messenger Systems

2003
Comparative actions of diazepam and other phosphodiesterase inhibitors on the effects of noradrenaline in rat myocardium.
    Pharmacology & toxicology, 2003, Volume: 93, Issue:1

    Topics: Adenine; Animals; Cyclic AMP; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; Female; In Vitro Techniques; Isoenzymes; Male; Milrinone; Myocardial Contraction; Norepinephrine; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Rolipram; Xanthines

2003
Phosphoinositide 3-kinase is involved in Xenopus and Labrus melanophore aggregation.
    Cellular signalling, 2003, Volume: 15, Issue:12

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Androstadienes; Animals; Chromones; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Dose-Response Relationship, Drug; Kinetics; Melanocyte-Stimulating Hormones; Melanophores; Melanosomes; Melatonin; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Norepinephrine; Papaverine; Perciformes; Phosphatidylinositol 3-Kinases; Phosphodiesterase Inhibitors; Phosphoinositide-3 Kinase Inhibitors; Phosphoric Diester Hydrolases; Phosphorylation; Rolipram; Signal Transduction; Wortmannin; Xenopus laevis

2003
Basal nitric oxide modulates vascular effects of a peptide activating protease-activated receptor 2.
    Cardiovascular research, 2003, Nov-01, Volume: 60, Issue:2

    Topics: Adenine; Adenylyl Cyclase Inhibitors; Animals; Aorta; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Male; Nitric Oxide; Oligopeptides; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Receptor, PAR-2; Rolipram; Vasodilator Agents

2003
Structural determinants for inhibitor specificity and selectivity in PDE2A using the wheat germ in vitro translation system.
    Biochemistry, 2005, Jun-14, Volume: 44, Issue:23

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Adenine; Amino Acid Sequence; Binding Sites; Catalytic Domain; Cell-Free System; Crystallography, X-Ray; Cyclic Nucleotide Phosphodiesterases, Type 2; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclic Nucleotide Phosphodiesterases, Type 5; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphodiesterase Inhibitors; Protein Binding; Protein Biosynthesis; Rolipram; Sequence Alignment; Substrate Specificity; Triticum

2005
Alpha1-antitrypsin, old dog, new tricks. Alpha1-antitrypsin exerts in vitro anti-inflammatory activity in human monocytes by elevating cAMP.
    The Journal of biological chemistry, 2007, Mar-23, Volume: 282, Issue:12

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; alpha 1-Antitrypsin; Anti-Inflammatory Agents; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 4; Endotoxins; Humans; Interleukin-10; Lipopolysaccharides; Monocytes; Phosphodiesterase Inhibitors; Rolipram; Tumor Necrosis Factor-alpha

2007
Inhibition of ATP release from erythrocytes: a role for EPACs and PKC.
    Microcirculation (New York, N.Y. : 1994), 2011, Volume: 18, Issue:2

    Topics: Adenine; Adenosine Triphosphate; Cilostazol; Colforsin; Cyclic AMP; Enzyme Activation; Erythrocytes; Guanine Nucleotide Exchange Factors; Humans; Iloprost; In Vitro Techniques; Isoproterenol; Models, Biological; Naphthalenes; Phosphodiesterase Inhibitors; Protein Kinase C; Rolipram; Signal Transduction; Tetradecanoylphorbol Acetate; Tetrazoles; Thionucleotides

2011
Role of phosphodiesterase 2 in growth and invasion of human malignant melanoma cells.
    Cellular signalling, 2014, Volume: 26, Issue:9

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenine; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 2; Humans; Melanoma; RNA Interference; RNA, Small Interfering; Rolipram

2014
cAMP signaling primes lung endothelial cells to activate caspase-1 during
    American journal of physiology. Lung cellular and molecular physiology, 2020, 05-01, Volume: 318, Issue:5

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenine; Alprostadil; Animals; Caspase 1; Cell Proliferation; Colforsin; Cyclic AMP; Cyclic GMP; Dinoprostone; Endothelial Cells; Gene Expression Regulation; Host-Pathogen Interactions; Inflammasomes; Interleukin-1beta; Lung; Primary Cell Culture; Pseudomonas aeruginosa; Rats; Rolipram; Signal Transduction; Single-Cell Analysis

2020
Phosphodiesterases 2, 3 and 4 can decrease cardiac effects of H
    Naunyn-Schmiedeberg's archives of pharmacology, 2021, Volume: 394, Issue:6

    Topics: Adenine; Animals; Cyclic Nucleotide Phosphodiesterases, Type 2; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Female; Heart Atria; Heart Rate; Histamine; Humans; Male; Mice; Mice, Transgenic; Phosphodiesterase Inhibitors; Quinolones; Receptors, Histamine H2; Rolipram

2021