adenine and pyrimidinones

adenine has been researched along with pyrimidinones in 138 studies

Research

Studies (138)

TimeframeStudies, this research(%)All Research%
pre-19907 (5.07)18.7374
1990's6 (4.35)18.2507
2000's74 (53.62)29.6817
2010's49 (35.51)24.3611
2020's2 (1.45)2.80

Authors

AuthorsStudies
Kenny, GE; McIvor, RS1
Schäfer, R; Schwartz, AC1
Bailey, P; Bryant, S; Burrs, A; Doctor, VM1
Grunberger, D; Pitha, J; Pitha, PM; Reynolds, F1
Hanlon, S; Nagel, GM1
Behrman, EJ; Subbaraman, J; Subbaraman, LR1
Egerton, RF; Misra, M1
Burkard, ME; Kierzek, R; Turner, DH1
Henriksen, U1
Cadman, J1
Schouten, J1
Honda, H; Imai, E; Kimura, H; Matsuno, K; Sakurazawa, S1
Gallant, JE1
Brun, S; Di Mascio, M; Ho, DD; Hogan, C; Hurley, A; Louie, M; Markowitz, M; Perelson, AS; Rooney, J; Ruiz, N; Simon, V; Sun, E1
Abad, S; Blanche, P; Chauvelot-Moachon, L; Daniel, N; Kélaïdi, C; Nazal, EM; Rollot, F; Saba, M1
Carter, M1
Rappaport, HP1
Evans, GB; Furneaux, RH; Schramm, VL; Singh, V; Tyler, PC1
Lok, AS1
Chaix, ML; Delaugerre, C; Peytavin, G; Roudiere, L; Rouzioux, C; Viard, JP1
Bannister, A; Day, SL; Fisher, M; Hankins, M; Leake Date, HA1
Dalmau, D; Ferrer, E; Gatell, JM; Iniguez, D; Knobel, H; Leon, A; Niubo, J; Podzamczer, D; Polo, C; Ruiz, I1
Mallal, S; Nolan, D; Reiss, P1
Coco, J; DeJesus, E; Grinsztejn, B; Johnson, M; Lazzarin, A; Lichtenstein, K; Rightmire, A; Rodriguez, C; Sankoh, S; Wilber, R1
Coco, J; DeJesus, E; Grinsztejn, B; Johnson, M; Lazzarin, A; Lichtenstein, K; McLaren, C; Odeshoo, L; Rightmire, A; Rodriguez, C; Wirtz, V1
Bonjoch, A; Bravo, I; Clotet, B; Heilek-Sneider, GM; Martinez-Picado, J; Moltó, J; Negredo, E; Ruiz, L; Valle, M1
Hussain, S; Khayat, A; Rathore, MH; Tolaymat, A1
Brown, NA; Chao, GC; Fielman, BA; Lloyd, DM; Zhou, XJ1
Gatanaga, H; Genka, I; Honda, M; Kikuchi, Y; Kimura, S; Oka, S; Tachikawa, N; Tanuma, J; Teruya, K; Ueda, A; Yazaki, H1
Alvarez, ML; Cihlar, T; Cordobilla, B; Domingo, JC; Domingo, P; Giralt, M; Guallar, J; López-Dupla, M; Sánchez de la Rosa, R; Saumoy, M; Torres, F; Vidal, F; Villarroya, F1
Baker, RK; Brooks, JT; Buchacz, K; Chmiel, JS; Moorman, A; Wood, KC; Young, B1
Bainbridge, A; Jäger, HR; Miller, RF; Usiskin, SI1
Amoroso, A; Chan-Tack, KM; Kopack, AM; Polk, C1
Gish, RG1
Hadziyannis, SJ1
Calvez, V; Chaix, ML; Delaugerre, C; Girard, PM; Katlama, C; Marcelin, AG; Morand-Joubert, L; Soulié, C1
Garcia-Gasco, P; Sheldon, J; Soriano, V1
Anderson, PL; Aquilante, CL; Bushman, LR; Carten, ML; Delahunty, T; Fletcher, CV; King, TM; Kiser, JJ; Wolfe, P1
Cascone, A; Colella, G; Di Martino, F; Filippini, A; Filippini, P; Lanza, A; Martini, S; Masiello, A; Pisapia, R1
Acosta, EP; Binongo, JN; Chuck, SK; Lennox, JL; Ofotokun, I; Palau, M1
Corona, G; Innocenti, F; Sandron, S; Sartor, I; Tirelli, U; Toffoli, G; Vaccher, E1
Bridges, AS; Cohen, MS; Corbett, AH; Dumond, JB; Jung, BH; Kashuba, AD; Patterson, KB; Rezk, NL; Stewart, PW; Yeh, RF1
Niederau, C1
Brown, NA; Bzowej, N; Chan, HL; Chao, YC; Cho, M; Harb, G; Heathcote, EJ; Jeffers, L; Kaiser, R; Lai, CL; Marcellin, P; Minuk, GY; Moon, YM; Myers, RP; Qiao, XJ; Sievert, W1
Sánchez-Tapias, JM1
Goto, T; Kato, N; Omata, M1
Geretti, AM1
Mauss, S1
Delso, I; Merino, P; Tejero, T1
Bulgin-Coleman, D; Fath, M; Fontaine, L; Kantor, C; Mieras, J; Pierone, G; Shearer, J1
Ayoub, WS; Keeffe, EB1
Yim, HJ1
Ray, AS; Rhodes, GR; Wright, MR1
Cotter, BR; Currier, JS; Dubé, MP; Fichtenbaum, CJ; Gerschenson, M; Komarow, L; Mitchell, CK; Murphy, RL; Parker, RA; Squires, K; Stein, JH; Torriani, FJ1
Chan, HL; Lui, YY1
Beckebaum, S; Cicinnati, VR; Gerken, G; Sotiropoulos, GC1
Li, B; Patty, A; Seifer, M; Serra, I; Standring, DN1
Burda, JV; Futera, Z; Klenko, J; Sponer, J; Sponer, JE1
García Buey, L; González Mateos, F; Moreno Otero, R1
Buti, M1
González-Diéguez, ML; Rodríguez, M1
Barreiro, P; García-Samaniego, J; Martín-Carbonero, L1
Chien, RN; Liaw, YF1
Buster, EH; Janssen, HL; Schalm, SW1
Colombo, M; Lampertico, P1
Keeffe, EB; Nguyen, MH1
Moreno, V; Valencia, ME1
Amini-Bavil-Olyaee, S; Herbers, U; Luedde, T; Sheldon, J; Tacke, F; Trautwein, C1
Ayen, R; Clotet, B; Grassi, J; Levi, M; Negredo, E; Pruvost, A; Puig, J; Théodoro, F1
Liaw, YF1
Belsey, E; Berzins, B; Chen, D; Choi, J; da Silva, B; Gerschenson, M; Kim, C; Libutti, DE; McComsey, GA; Murphy, RL; Shore, J; Taiwo, B; Weinstein, J1
Borroto-Esoda, K; Curtis, M; Miller, MD; Qi, X; Zhu, Y1
Bellos, N; Fine, D; Kumar, PN; Lackey, P; Patel, P; Shaefer, MS; Sloan, L; Smith, KY; Sutherland-Phillips, DH; Vavro, C; Wannamaker, P; Yau, L1
Andrade, A; Eshleman, SH; Flanigan, T; Flexner, C; Gross, R; Hogg, E; Lalama, C; Mildvan, D; Reisler, R; Rosenkranz, S; Salomon, N; Santana, J; Tierney, C; Wiggins, I1
Cong, M; Jia, J; Li, H; Liu, T; Ma, H; Ou, X; Ren, J; Wang, B; Wang, P; Wang, X; You, H1
Barreiro, P; Fernández, JV; Labarga, P; Medrano, J; Soriano, V; Tuma, P; Vispo, E1
Chetchotisakd, P1
Sankawa, Y1
Bangsberg, DR1
Lin, Q; Zhang, DZ1
Absalon, J; Andrade-Villanueva, J; Chetchotisakd, P; Corral, J; David, N; Echevarria, J; Lataillade, M; Mancini, M; McGrath, D; Molina, JM; Moyle, G; Percival, L; Wirtz, V; Yang, R1
Battegay, M; Bernasconi, E; Cavassini, M; Elzi, L; Furrer, H; Hirschel, B; Ledergerber, B; Marzolini, C; Vernazza, P; Weber, R1
Altice, FL; Springer, SA1
Marcellin, P; Perrillo, RP1
Chan, HL; Han, KH; Hou, JL; Kao, JH; Lui, YY; Mihm, U; Mohamed, R; Piratvisuth, T; Teo, EK; Tsoi, KK; Wong, GL; Wong, VW1
Chee, GM; Poordad, F1
Absalon, J; Malan, N; Mancini, M; McGrath, D; Su, J; Wirtz, V; Yang, R1
Bao, H; Furman, PA; Korba, B; Micolochick Steuer, HM; Murakami, E; Niu, C; Tolstykh, T1
Chien, RN1
Chen, H; Li, T; Shen, J; Wu, B1
Bernstein, B; Cohen, D; da Silva, B; Fredrick, L; González-García, J; Johnson, M; Naylor, C; Sloan, L1
Hart, JR; Hillmann, P; Hofmann, BT; Sun, M; Vogt, PK1
Benabdelmoumen, G; Bouvet, E; Christian, B; Muller, P; Peyrouse, E; Prazuck, T; Quertainmont, Y; Rabaud, C; Tosini, W1
Aba, YT; Aoussi, EF; Bissagnene, E; Eholié, SP; Ehui, E; Kadio, A; Kakou, AR; Kassi, A; Ondounda, M; Ouattara, I; Tanon, A1
Alston-Smith, B; Asmelash, A; Atwine, D; Chipato, T; Conradie, F; Currier, JS; Eshleman, S; Hakim, J; Hogg, E; Hosseinipour, MC; Hughes, MD; Kanyama, C; Lockman, S; McIntyre, J; Mellors, JW; Mngqibisa, R; Mohapi, L; Purcelle-Smith, E; Rahim, S; Rooney, J; Salata, RA; Sawe, F; Schooley, RT; Shaffer, D; Siika, A; Stringer, E; Walawander, A; Wools-Kaloustian, K; Zheng, Y1
Bourlière, M; Kahloun, A; Zoulim, F1
Benhamou, Y; Pais, R1
Back, DJ; Boffito, M; Jackson, AG; Mandalia, S; Moyle, GJ; Randell, PA; Taylor, J; Tjia, JF1
Abuduheilili, X; Dong, JP; Hou, CS; Jiao, XJ; Li, T; Li, XG; Liu, BM; Sun, XW; Wang, YH; Xu, J; Yan, CH; Yan, L; Yang, JX; Zhuang, H1
Leung, N1
Papatheodoridis, GV1
Zoulim, F1
Mallet, V; Pol, S; Vallet-Pichard, A1
Bentley, TG; Broder, MS; Chang, EY; Juday, T; Uy, J1
de Béthune, MP; De Meyer, S; Dierynck, I; Lathouwers, E; Lavreys, L; Picchio, G; Van de Casteele, T1
Black, JL; Burgess, JK; Ge, Q; Moir, LM; Oliver, BG; Shepherd, PR; Trian, T1
Dai, J; Ji, D; Li, L; Li, X; Liu, Y; Ren, X; Wang, C; Wang, L; Wong, VW; Xu, D; Xu, Z; Yao, Z; Zhang, L; Zhong, Y; Zoulim, F1
Cong, M; Jia, J; Liu, T; Ma, H; Ou, X; Wang, B; Wang, P; Wang, Q; Wu, X; You, H1
Tornai, I1
Gatanaga, H; Kikuchi, Y; Nagata, N; Nishijima, T; Oka, S; Teruya, K; Tsukada, K; Watanabe, K1
Giles, M; Sasadeusz, J; Visvanathan, K1
Razonable, RR1
Al-Hashimi, HM; Brooks, CL; Eichhorn, CD; Feng, J; Suddala, KC; Walter, NG1
Suzuki, F2
García-Alonso, FJ; Martín-Mateos, RM; Moreira Vicente, V1
Buckheit, KW; Buckheit, RW; Goldman, L; Gwozdz, G; Ham, AS; Kiser, PF; Lakougna, H; Nagaraja, U; Shi, L; Ugaonkar, SR1
Fontana, RJ; Singal, AK1
Almasio, PL; Bertino, G; Brandolino, N; Bruno, S; Caroleo, B; Cosco, L; Di Marco, V; Foti, G; Frugiuele, P; Galdieri, A; Madonia, S; Montalto, G; Portelli, V; Russello, M; Sapienza, M; Scifo, G; Siciliano, R; Spadaro, A; Stroffolini, T; Surace, L1
Bai, L; Chen, EQ; Liang, LB; Tang, H; Wang, JR; Yan, LB; Zhou, TY1
Wincel, H1
Buckheit, KW; Buckheit, RW; Dezzutti, CS; Gwozdz, G; Mahalingam, A; Shetler, C; Ugaonkar, SR1
Haishima, Y; Hasegawa, C; Isama, K; Kawakami, T; Matsuoka, A; Niimi, S; Tanoue, A; Yuba, T1
Blanco, B; Del Cañizo, MC; Herrero-Sánchez, MC; Rodríguez-Serrano, C; Sánchez-Barba, M1
Clinch, K; Evans, GB; Freitas, EO; Guan, R; Meyer-Fernandes, JR; Nico, D; Palatnik-de-Sousa, CB; Schramm, VL; Tyler, PC1
Alves-Silva, MV; Clinch, K; Evans, GB; Freitas, EO; Morrot, A; Nico, D; Palatnik-de-Sousa, CB; Schramm, VL; Tyler, PC1
Barone, V; Biczysko, M; Bloino, J; Fornaro, T1
Gupta, P; Mukhopadhyay, CK; Pandey, HS; Seth, P; Singh, P1
Chau, N; Korprasertthaworn, P; Miners, JO; Nair, PC; Rowland, A1
Bandyopadhyay, T; Ganguly, B; Ghosh, S; Jana, K; Wakchaure, PD1
D'Alonzo, D; De Fenza, M; Esposito, A; Guaragna, A1

Reviews

34 review(s) available for adenine and pyrimidinones

ArticleYear
New treatment of chronic hepatitis B.
    Seminars in liver disease, 2004, Volume: 24 Suppl 1

    Topics: Adenine; Animals; Antiviral Agents; Arabinofuranosyluracil; Deoxycytidine; Drug Resistance, Viral; Emtricitabine; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Organophosphorus Compounds; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Treatment Outcome

2004
Adverse effects of antiretroviral therapy for HIV infection: a review of selected topics.
    Expert opinion on drug safety, 2005, Volume: 4, Issue:2

    Topics: Adenine; Alkynes; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cardiovascular Diseases; Cyclopropanes; Drug Monitoring; Drug Therapy, Combination; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Kidney Diseases; Lopinavir; Metabolic Syndrome; Nevirapine; Organophosphonates; Oxazines; Pyrimidinones; Risk Factors; Tenofovir

2005
Improving outcomes for patients with chronic hepatitis B.
    Current gastroenterology reports, 2007, Volume: 9, Issue:1

    Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Guanine; Hepatitis B Vaccines; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Polyethylene Glycols; Pyrimidinones; Recombinant Proteins; Telbivudine; Thymidine; Treatment Outcome; Viral Load

2007
Treatment paradigms on hepatitis B e antigen-negative chronic hepatitis B patients.
    Expert opinion on investigational drugs, 2007, Volume: 16, Issue:6

    Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Thymidine

2007
Treatment of chronic hepatitis B in HIV-infected patients in 2007.
    Journal of HIV therapy, 2007, Volume: 12, Issue:1

    Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B, Chronic; HIV Infections; Humans; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine

2007
[Pharmacological agents for the treatment of chronic hepatitis B].
    Gastroenterologia y hepatologia, 2008, Volume: 31, Issue:3

    Topics: Adenine; Antiviral Agents; Clinical Trials as Topic; Drug Therapy, Combination; Follow-Up Studies; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Polyethylene Glycols; Pyrimidinones; Recombinant Proteins; Reverse Transcriptase Inhibitors; Telbivudine; Thymidine; Time Factors; Treatment Outcome

2008
Resistance testing methodologies and mechanisms of resistance.
    Journal of HIV therapy, 2007, Volume: 12, Issue:4

    Topics: Adenine; Anti-HIV Agents; CCR5 Receptor Antagonists; Drug Resistance, Viral; HIV; Humans; Lopinavir; Nitriles; Organophosphonates; Pyridazines; Pyrimidines; Pyrimidinones; Tenofovir

2007
Clinical implications of resistance patterns against HBV-polymerase inhibitors for the treatment of chronic hepatitis B.
    Journal of HIV therapy, 2007, Volume: 12, Issue:4

    Topics: Adenine; Drug Resistance, Viral; Drug Therapy, Combination; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine

2007
Current developments in the synthesis and biological activity of aza-C-nucleosides: immucillins and related compounds.
    Current medicinal chemistry, 2008, Volume: 15, Issue:10

    Topics: Adenine; Adenosine; Aza Compounds; Glycoside Hydrolases; N-Glycosyl Hydrolases; Nucleosides; Purine Nucleosides; Purine-Nucleoside Phosphorylase; Pyrimidinones; Pyrroles; Pyrrolidines

2008
Review article: current antiviral therapy of chronic hepatitis B.
    Alimentary pharmacology & therapeutics, 2008, Volume: 28, Issue:2

    Topics: Adenine; Antiviral Agents; Carcinoma, Hepatocellular; Deoxycytidine; Drug Resistance, Viral; Emtricitabine; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Liver Cirrhosis; Nucleosides; Organophosphonates; Polyethylene Glycols; Pyrimidinones; Recombinant Proteins; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine; Virus Replication

2008
[Management of antiviral-resistant chronic hepatitis B virus infection].
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2008, Volume: 51, Issue:6

    Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Drug Resistance, Multiple, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Mutation; Nucleosides; Organophosphonates; Practice Guidelines as Topic; Pyrimidinones; Telbivudine; Thymidine; Treatment Outcome

2008
A review of telbivudine for the management of chronic hepatitis B virus infection.
    Expert opinion on drug metabolism & toxicology, 2008, Volume: 4, Issue:10

    Topics: Adenine; Antiviral Agents; Clinical Trials as Topic; Drug Evaluation, Preclinical; Drug Resistance, Viral; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Thymidine

2008
Hepatitis B and liver transplantation: 2008 update.
    Reviews in medical virology, 2009, Volume: 19, Issue:1

    Topics: Adenine; Antiviral Agents; Drug Therapy, Combination; Guanine; Hepatitis B; Hepatitis B Vaccines; Humans; Immunoglobulins; Lamivudine; Liver Transplantation; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine

2009
[Interferon in hepatitis B].
    Enfermedades infecciosas y microbiologia clinica, 2008, Volume: 26 Suppl 7

    Topics: Adenine; Antiviral Agents; Clinical Trials as Topic; Drug Therapy, Combination; Genotype; Guanine; Hepatitis B; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Multicenter Studies as Topic; Nucleosides; Organophosphonates; Polyethylene Glycols; Pyrimidinones; Randomized Controlled Trials as Topic; Recombinant Proteins; Telbivudine; Thymidine; Treatment Outcome

2008
[Nucleoside and nucleotide analogs in the treatment of chronic hepatitis B].
    Enfermedades infecciosas y microbiologia clinica, 2008, Volume: 26 Suppl 7

    Topics: Adenine; Antiviral Agents; Clinical Trials as Topic; Deoxycytidine; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine; Genotype; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Multicenter Studies as Topic; Nucleosides; Organophosphonates; Pyrimidinones; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine; Treatment Outcome; Virus Replication

2008
[Clinical management of patients with chronic hepatitis B virus infection].
    Enfermedades infecciosas y microbiologia clinica, 2008, Volume: 26 Suppl 7

    Topics: Adenine; Antiviral Agents; Biopsy; Combined Modality Therapy; Deoxycytidine; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine; Female; Genotype; Guanine; Hepatitis B Antibodies; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Liver; Liver Transplantation; Male; Nucleosides; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine; Virus Replication

2008
[Hepatitis B in patients with HIV infection].
    Enfermedades infecciosas y microbiologia clinica, 2008, Volume: 26 Suppl 7

    Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Antiviral Agents; Comorbidity; Deoxycytidine; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine; Guanine; Hepatitis B; Hepatitis B Vaccines; Hepatitis B virus; HIV; HIV Infections; Humans; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Practice Guidelines as Topic; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine; Virus Replication

2008
Nucleos(t)ide analogues for hepatitis B virus: strategies for long-term success.
    Best practice & research. Clinical gastroenterology, 2008, Volume: 22, Issue:6

    Topics: Adenine; Adenine Nucleotides; Alanine Transaminase; Carcinoma, Hepatocellular; DNA, Viral; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver Cirrhosis; Liver Neoplasms; Nucleosides; Organophosphonates; Pyrimidinones; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Telbivudine; Thymidine; Treatment Outcome; Virus Replication

2008
Peginterferon for the treatment of chronic hepatitis B in the era of nucleos(t)ide analogues.
    Best practice & research. Clinical gastroenterology, 2008, Volume: 22, Issue:6

    Topics: Adenine; Antiviral Agents; DNA, Viral; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Polyethylene Glycols; Practice Guidelines as Topic; Pyrimidinones; Randomized Controlled Trials as Topic; Recombinant Proteins; Telbivudine; Tenofovir; Thymidine; Treatment Outcome

2008
HBeAg-negative chronic hepatitis B: why do I treat my patients with nucleos(t)ide analogues.
    Liver international : official journal of the International Association for the Study of the Liver, 2009, Volume: 29 Suppl 1

    Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Virus Replication

2009
Chronic hepatitis B: early viral suppression and long-term outcomes of therapy with oral nucleos(t)ides.
    Journal of viral hepatitis, 2009, Volume: 16, Issue:3

    Topics: Adenine; Administration, Oral; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Thymidine; Time Factors; Treatment Outcome

2009
On-treatment outcome prediction and adjustment during chronic hepatitis B therapy: now and future.
    Antiviral therapy, 2009, Volume: 14, Issue:1

    Topics: Adenine; Antiviral Agents; Cost-Benefit Analysis; DNA, Viral; Drug Resistance, Multiple, Viral; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Medication Adherence; Nucleosides; Organophosphonates; Polyethylene Glycols; Prognosis; Pyrimidinones; Recombinant Proteins; Telbivudine; Thymidine; Time Factors; Treatment Outcome

2009
The CASTLE study: atazanavir/r versus lopinavir/r in antiretroviral-naive patients.
    Expert review of anti-infective therapy, 2009, Volume: 7, Issue:7

    Topics: Adenine; Anti-HIV Agents; Atazanavir Sulfate; Clinical Trials, Phase III as Topic; Deoxycytidine; Drug Therapy, Combination; Emtricitabine; HIV Infections; HIV-1; Humans; Lopinavir; Multicenter Studies as Topic; Oligopeptides; Organophosphonates; Pyridines; Pyrimidinones; Randomized Controlled Trials as Topic; Ritonavir; Tenofovir; Treatment Outcome

2009
Effect of newer oral antiviral agents on future therapy of chronic hepatitis B.
    Antiviral therapy, 2010, Volume: 15, Issue:1

    Topics: Adenine; Administration, Oral; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B, Chronic; Humans; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Treatment Outcome

2010
On-treatment monitoring of chronic hepatitis B virus infection: an Asian-Pacific perspective.
    Journal of gastroenterology and hepatology, 2010, Volume: 25, Issue:5

    Topics: Adenine; Antiviral Agents; Asia; Biomarkers; DNA, Viral; Drug Monitoring; Drug Resistance, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Time Factors; Treatment Outcome; Viral Load; Virus Replication

2010
Treatment of HBeAg-positive chronic hepatitis B with nucleos(t)ide analogues.
    Liver international : official journal of the International Association for the Study of the Liver, 2011, Volume: 31 Suppl 1

    Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Treatment Outcome

2011
Hepatitis B virus resistance to antiviral drugs: where are we going?
    Liver international : official journal of the International Association for the Study of the Liver, 2011, Volume: 31 Suppl 1

    Topics: Adenine; Antiviral Agents; Capsid; Clinical Protocols; Drug Resistance, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Virus Internalization; Virus Replication

2011
The impact of human immunodeficiency virus on viral hepatitis.
    Liver international : official journal of the International Association for the Study of the Liver, 2011, Volume: 31 Suppl 1

    Topics: Adenine; Antiviral Agents; Deoxycytidine; Disease Progression; Drug Therapy, Combination; Emtricitabine; Guanine; Hepatitis B; Hepatitis C; Hepatitis Viruses; HIV Infections; Humans; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine

2011
[Interferon-based versus direct antiviral therapy in patients with chronic hepatitis B].
    Orvosi hetilap, 2011, May-29, Volume: 152, Issue:22

    Topics: Adenine; Antiviral Agents; DNA, Viral; Drug Therapy, Combination; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Nucleosides; Nucleotides; Organophosphonates; Polyethylene Glycols; Pyrimidinones; Recombinant Proteins; Telbivudine; Tenofovir; Thymidine; Treatment Outcome

2011
Antiviral therapy for hepatitis B infection during pregnancy and breastfeeding.
    Antiviral therapy, 2011, Volume: 16, Issue:5

    Topics: Adenine; Antiviral Agents; Breast Feeding; Female; Guanine; Hepatitis B; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Placenta; Pregnancy; Pregnancy Complications, Infectious; Pyrimidinones; Telbivudine; Tenofovir; Thymidine

2011
Antiviral drugs for viruses other than human immunodeficiency virus.
    Mayo Clinic proceedings, 2011, Volume: 86, Issue:10

    Topics: Acyclovir; Adenine; Amantadine; Antiviral Agents; Comorbidity; Drug Therapy, Combination; Foscarnet; Ganciclovir; Guanine; Hepatitis; Hepatitis B, Chronic; Hepatitis C; Herpesviridae Infections; HIV Infections; Humans; Influenza, Human; Interferons; Lamivudine; Nucleosides; Oligopeptides; Organophosphonates; Oseltamivir; Proline; Protease Inhibitors; Pyrimidinones; Ribavirin; Telbivudine; Thymidine; Valacyclovir; Valganciclovir; Valine; Virus Replication; Zanamivir

2011
[Pharmacological treatment of acute hepatitis B].
    Medicina clinica, 2012, May-19, Volume: 138, Issue:14

    Topics: Acute Disease; Adenine; Antiviral Agents; Guanine; Hepatitis B; Humans; Lamivudine; Nucleosides; Organophosphonates; Practice Guidelines as Topic; Pyrimidinones; Spain; Telbivudine; Tenofovir; Thymidine; Treatment Outcome

2012
Meta-analysis: oral anti-viral agents in adults with decompensated hepatitis B virus cirrhosis.
    Alimentary pharmacology & therapeutics, 2012, Volume: 35, Issue:6

    Topics: Adenine; Administration, Oral; Adult; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver Cirrhosis; Nucleosides; Organophosphonates; Pyrimidinones; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine; Time Factors; Treatment Outcome; Viral Load

2012
[New drugs of treatment of patients with chronic hepatitis B].
    Nihon rinsho. Japanese journal of clinical medicine, 2012, Volume: 70, Issue:4

    Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Deoxycytidine; Emtricitabine; Hepatitis B, Chronic; Humans; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine

2012

Trials

23 trial(s) available for adenine and pyrimidinones

ArticleYear
Determining the relative efficacy of highly active antiretroviral therapy.
    The Journal of infectious diseases, 2003, Mar-15, Volume: 187, Issue:6

    Topics: Adenine; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cohort Studies; Cyclopropanes; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Lopinavir; Organophosphonates; Organophosphorus Compounds; Oxazines; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Tenofovir; Treatment Outcome

2003
Early virological failure with a combination of tenofovir, didanosine and efavirenz.
    Antiviral therapy, 2005, Volume: 10, Issue:1

    Topics: Adenine; Adult; Aged; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Didanosine; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Lopinavir; Male; Middle Aged; Mutation; Organophosphonates; Oxazines; Pyrimidinones; RNA, Viral; Tenofovir; Time Factors; Treatment Failure; Viremia

2005
Atazanavir plus ritonavir or saquinavir, and lopinavir/ritonavir in patients experiencing multiple virological failures.
    AIDS (London, England), 2005, Apr-29, Volume: 19, Issue:7

    Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; CD4 Lymphocyte Count; Cholesterol; Drug Administration Schedule; Drug Resistance, Multiple, Viral; HIV Infections; HIV-1; Humans; Lipids; Lopinavir; Oligopeptides; Organophosphonates; Pyridines; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Saquinavir; Tenofovir; Viral Load

2005
96-week comparison of once-daily atazanavir/ritonavir and twice-daily lopinavir/ritonavir in patients with multiple virologic failures.
    AIDS (London, England), 2006, Mar-21, Volume: 20, Issue:5

    Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Didanosine; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lipids; Lopinavir; Male; Oligopeptides; Organophosphonates; Pyridines; Pyrimidinones; Ritonavir; RNA, Viral; Saquinavir; Tenofovir; Time Factors; Treatment Outcome

2006
Increased antiretroviral potency by the addition of enfuvirtide to a four-drug regimen in antiretroviral-naive, HIV-infected patients.
    Antiviral therapy, 2006, Volume: 11, Issue:1

    Topics: Adenine; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Drug Synergism; Drug Therapy, Combination; Enfuvirtide; HIV Envelope Protein gp41; HIV Fusion Inhibitors; HIV Infections; Humans; Lamivudine; Lopinavir; Organophosphonates; Oxazines; Patient Compliance; Peptide Fragments; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Tenofovir; Treatment Outcome

2006
Pharmacokinetics of telbivudine in healthy subjects and absence of drug interaction with lamivudine or adefovir dipivoxil.
    Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:7

    Topics: Adenine; Administration, Oral; Adult; Anti-HIV Agents; Antiviral Agents; Area Under Curve; Drug Interactions; Drug Therapy, Combination; Female; Humans; Lamivudine; Male; Middle Aged; Nucleosides; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Thymidine

2006
Renal function in patients receiving tenofovir with ritonavir/lopinavir or ritonavir/atazanavir in the HIV Outpatient Study (HOPS) cohort.
    Journal of acquired immune deficiency syndromes (1999), 2006, Dec-15, Volume: 43, Issue:5

    Topics: Adenine; Adult; Atazanavir Sulfate; Cohort Studies; Female; HIV Infections; Humans; Kidney; Lopinavir; Male; Oligopeptides; Organophosphonates; Pyridines; Pyrimidinones; Ritonavir; Tenofovir

2006
The effect of lopinavir/ritonavir on the renal clearance of tenofovir in HIV-infected patients.
    Clinical pharmacology and therapeutics, 2008, Volume: 83, Issue:2

    Topics: Adenine; Administration, Oral; Adult; Antiretroviral Therapy, Highly Active; Case-Control Studies; Drug Interactions; Female; Genotype; HIV Infections; HIV Protease Inhibitors; Humans; Kidney; Lopinavir; Male; Membrane Transport Proteins; Middle Aged; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Organic Anion Transport Protein 1; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; Tenofovir; Treatment Outcome

2008
Lopinavir/Ritonavir pharmacokinetic profile: impact of sex and other covariates following a change from twice-daily to once-daily therapy.
    Journal of clinical pharmacology, 2007, Volume: 47, Issue:8

    Topics: Adenine; Adult; Area Under Curve; Capsules; Chromatography, High Pressure Liquid; Drug Administration Schedule; Drug Combinations; Drug Interactions; Female; HIV Infections; HIV Protease Inhibitors; Humans; Lopinavir; Male; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; Sex Factors; Tenofovir

2007
Treatment of hepatitis B e antigen positive chronic hepatitis with telbivudine or adefovir: a randomized trial.
    Annals of internal medicine, 2007, Dec-04, Volume: 147, Issue:11

    Topics: Adenine; Adolescent; Adult; Aged; Antiviral Agents; Biomarkers; DNA, Viral; Drug Therapy, Combination; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Thymidine; Viral Load

2007
An open-label pilot study to determine the efficacy of lopinavir/ritonavir and tenofovir DF in the treatment of HIV-infected patients experiencing first virologic failure on a non-nucleoside-based regimen.
    AIDS patient care and STDs, 2008, Volume: 22, Issue:4

    Topics: Adenine; Adult; Anti-HIV Agents; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lopinavir; Middle Aged; Organophosphonates; Pilot Projects; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Tenofovir; Treatment Outcome

2008
Endothelial function in human immunodeficiency virus-infected antiretroviral-naive subjects before and after starting potent antiretroviral therapy: The ACTG (AIDS Clinical Trials Group) Study 5152s.
    Journal of the American College of Cardiology, 2008, Aug-12, Volume: 52, Issue:7

    Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Brachial Artery; CD4 Lymphocyte Count; Cyclopropanes; Endothelium, Vascular; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Lopinavir; Male; Organophosphonates; Prospective Studies; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; Stavudine; Tenofovir; Time Factors; Zidovudine

2008
Pilot pharmacokinetic study of human immunodeficiency virus-infected patients receiving tenofovir disoproxil fumarate (TDF): investigation of systemic and intracellular interactions between TDF and abacavir, lamivudine, or lopinavir-ritonavir.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:5

    Topics: Adenine; Adult; Anti-HIV Agents; Area Under Curve; Cross-Sectional Studies; Dideoxynucleosides; Drug Interactions; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Longitudinal Studies; Lopinavir; Male; Middle Aged; Organophosphonates; Pilot Projects; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; Tenofovir; Treatment Outcome

2009
Randomized, double-blind, placebo-matched, multicenter trial of abacavir/lamivudine or tenofovir/emtricitabine with lopinavir/ritonavir for initial HIV treatment.
    AIDS (London, England), 2009, Jul-31, Volume: 23, Issue:12

    Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cardiovascular Diseases; CD4 Lymphocyte Count; Deoxycytidine; Dideoxynucleosides; Double-Blind Method; Emtricitabine; Female; HIV Infections; HIV-1; Humans; Lamivudine; Lopinavir; Male; Organophosphonates; Pyrimidinones; Ritonavir; RNA, Viral; Tenofovir; Treatment Outcome

2009
Modified directly observed antiretroviral therapy compared with self-administered therapy in treatment-naive HIV-1-infected patients: a randomized trial.
    Archives of internal medicine, 2009, Jul-13, Volume: 169, Issue:13

    Topics: Adenine; Administration, Oral; Adolescent; Adult; Aged; Anti-HIV Agents; Deoxycytidine; Dose-Response Relationship, Drug; Emtricitabine; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Lopinavir; Male; Middle Aged; Organophosphonates; Pyrimidinones; Retrospective Studies; RNA, Viral; Stavudine; Tenofovir; Treatment Outcome; Young Adult

2009
Modified directly observed therapy to improve HIV treatment outcomes: little impact with potent, once-daily therapy in unselected antiretroviral-naïve patients.
    Current HIV/AIDS reports, 2009, Volume: 6, Issue:4

    Topics: Adenine; Anti-HIV Agents; Deoxycytidine; Directly Observed Therapy; Drug Administration Schedule; Drug Therapy, Combination; Emtricitabine; HIV Infections; HIV-1; Humans; Lopinavir; Medication Adherence; Organophosphonates; Pyrimidinones; Ritonavir; Self Administration; Stavudine; Tenofovir; Treatment Outcome

2009
Once-daily atazanavir/ritonavir compared with twice-daily lopinavir/ritonavir, each in combination with tenofovir and emtricitabine, for management of antiretroviral-naive HIV-1-infected patients: 96-week efficacy and safety results of the CASTLE study.
    Journal of acquired immune deficiency syndromes (1999), 2010, Volume: 53, Issue:3

    Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Deoxycytidine; Emtricitabine; Female; HIV Infections; HIV-1; Humans; Lipids; Lopinavir; Male; Middle Aged; Oligopeptides; Organophosphonates; Pyridines; Pyrimidinones; Ritonavir; RNA, Viral; Tenofovir; Treatment Outcome; Viral Load; Young Adult

2010
Gastrointestinal tolerability and quality of life in antiretroviral-naive HIV-1-infected patients: data from the CASTLE study.
    AIDS care, 2010, Volume: 22, Issue:6

    Topics: Adenine; Adult; Aged; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Deoxycytidine; Drug Therapy, Combination; Emtricitabine; Female; Gastrointestinal Diseases; HIV Infections; HIV-1; Humans; Irritable Bowel Syndrome; Lopinavir; Male; Medication Adherence; Middle Aged; Oligopeptides; Organophosphonates; Prospective Studies; Pyridines; Pyrimidinones; Quality of Life; Ritonavir; Surveys and Questionnaires; Tenofovir; Young Adult

2010
Short communication: Comparable safety and efficacy with once-daily versus twice-daily dosing of lopinavir/ritonavir tablets with emtricitabine + tenofovir DF in antiretroviral-naïve, HIV type 1-infected subjects: 96 week final results of the randomized t
    AIDS research and human retroviruses, 2010, Volume: 26, Issue:8

    Topics: Adenine; Anti-HIV Agents; Deoxycytidine; Diarrhea; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Emtricitabine; HIV Infections; HIV-1; Humans; Lopinavir; Organophosphonates; Pyrimidinones; Ritonavir; Tenofovir

2010
Antiretroviral therapies in women after single-dose nevirapine exposure.
    The New England journal of medicine, 2010, Oct-14, Volume: 363, Issue:16

    Topics: Adenine; Adult; Anti-HIV Agents; Anti-Retroviral Agents; CD4 Lymphocyte Count; Deoxycytidine; Drug Therapy, Combination; Emtricitabine; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Infectious Disease Transmission, Vertical; Kaplan-Meier Estimate; Linear Models; Lopinavir; Nevirapine; Organophosphonates; Pregnancy; Pregnancy Complications, Infectious; Pyrimidinones; Ritonavir; Statistics, Nonparametric; Tenofovir; Treatment Failure; Young Adult

2010
Effect of boosted fosamprenavir or lopinavir-based combinations on whole-body insulin sensitivity and lipids in treatment-naive HIV-type-1-positive men.
    Antiviral therapy, 2010, Volume: 15, Issue:8

    Topics: Adenine; Adipose Tissue; Adult; Anti-HIV Agents; Blood Glucose; Carbamates; Confidence Intervals; Drug Administration Schedule; Drug Combinations; Dyslipidemias; Furans; HIV Infections; HIV-1; Humans; Insulin; Insulin Resistance; Lamivudine; Lipids; Lopinavir; Male; Organophosphates; Organophosphonates; Pyrimidinones; Ritonavir; Sulfonamides; Tenofovir

2010
Virological characterization of patients failing darunavir/ritonavir or lopinavir/ritonavir treatment in the ARTEMIS study: 96-week analysis.
    Antiviral therapy, 2011, Volume: 16, Issue:1

    Topics: Adenine; Adult; Anti-HIV Agents; Darunavir; Deoxycytidine; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine; Female; Genetic Association Studies; HIV Infections; HIV-1; Humans; Lopinavir; Male; Mutation; Organophosphonates; Polymorphism, Genetic; Pyrimidinones; Ritonavir; RNA, Viral; Sulfonamides; Tenofovir; Treatment Failure; Viral Load

2011
Lamivudine plus adefovir or telbivudine plus adefovir for chronic hepatitis B patients with suboptimal response to adefovir.
    Antiviral therapy, 2012, Volume: 17, Issue:6

    Topics: Adenine; Adult; Biomarkers; DNA, Viral; Drug Therapy, Combination; Female; Genotype; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Nucleosides; Organophosphonates; Prospective Studies; Pyrimidinones; Telbivudine; Thymidine; Treatment Outcome; Young Adult

2012

Other Studies

81 other study(ies) available for adenine and pyrimidinones

ArticleYear
Differences in incorporation of nucleic acid bases and nucleosides by various Mycoplasma and Acholeplasma species.
    Journal of bacteriology, 1978, Volume: 135, Issue:2

    Topics: Acholeplasma laidlawii; Adenine; Cytosine; Deoxyribonucleosides; Guanine; Mycoplasma; Nucleosides; Purines; Pyrimidinones; Ribonucleosides; Uracil

1978
New amino acids, and heterocyclic compounds participating in the Stickland reaction of Clostridium sticklandii.
    Archiv fur Mikrobiologie, 1973, Nov-02, Volume: 93, Issue:3

    Topics: Adenine; Alcohol Oxidoreductases; Amino Acids; Anaerobiosis; Chromatography, Thin Layer; Clostridium; Electron Transport; Fluorescence; Fluorometry; Formates; Glucosephosphate Dehydrogenase; Glutamate Dehydrogenase; Glutamates; Heterocyclic Compounds; Histidine; L-Lactate Dehydrogenase; Methods; NAD; NADP; Oxidation-Reduction; Pyrimidinones; Uric Acid; Xanthines

1973
Separation of nucleotides, nucleosides and bases of DNA with cation exchange columns.
    Preparative biochemistry, 1973, Volume: 3, Issue:2

    Topics: Adenine; Animals; Cattle; Chromatography, Ion Exchange; Cytosine; Cytosine Nucleotides; Deoxyadenosines; Deoxycytidine; Deoxyribonucleases; Deoxyribonucleosides; Deoxyribonucleotides; DNA; Evaluation Studies as Topic; Formates; Guanine; Hydrolysis; Methods; Purines; Pyrimidinones; Quaternary Ammonium Compounds; Spectrophotometry, Ultraviolet; Thymidine; Thymine; Thymine Nucleotides; Thymus Gland

1973
Inhibition of cell-free protein synthesis by poly(9-vinyladenine), poly(1-vinyluracil), and the corresponding vinyl copolymer.
    Biochemistry, 1972, Aug-15, Volume: 11, Issue:17

    Topics: Adenine; Bacterial Proteins; Carbon Isotopes; Cell-Free System; Chemical Phenomena; Chemistry; Escherichia coli; Infrared Rays; Lysine; Phenylalanine; Polynucleotides; Polyvinyls; Pyrimidinones; Ribosomes; RNA, Transfer; Spectrophotometry; Ultraviolet Rays; Uracil; Valine; Vinyl Compounds

1972
Higher order associations of adenine and uracil by hydrogen bonding. II. Formation of complexes in mixed solutions of 9-ethyladenine and 1-cyclohexyluracil.
    Biochemistry, 1972, Feb-29, Volume: 11, Issue:5

    Topics: Adenine; Binding Sites; Chemical Phenomena; Chemistry; Chloroform; Cyclohexanes; Hydrogen; Infrared Rays; Kinetics; Mathematics; Osmolar Concentration; Osmotic Pressure; Polymers; Polynucleotides; Purines; Pyrimidinones; Spectrophotometry; Temperature; Uracil

1972
The reaction of nucleic acid components with m-chloroperoxybenzoic acid.
    Biochemistry, 1969, Volume: 8, Issue:7

    Topics: Adenine; Benzoates; Chemical Phenomena; Chemistry; Chlorine; Chromatography, Paper; Chromatography, Thin Layer; Cyclic N-Oxides; Hydrogen-Ion Concentration; Kinetics; Nucleic Acids; Nucleosides; Nucleotides; Osmolar Concentration; Peroxides; Potentiometry; Pyrimidinones; Spectrophotometry; Temperature; Thymidine; Thymine; Ultraviolet Rays; Uracil; Uridine

1969
Assessment of electron irradiation damage to biomolecules by electron diffraction and electron energy-loss spectroscopy.
    Ultramicroscopy, 1984, Volume: 15, Issue:4

    Topics: Adenine; Amino Acids; Cysteine; Cytosine; Electrons; Methionine; Microscopy, Electron; Pyrimidinones; Spectrum Analysis; Thymine; Uracil; Valine

1984
Thermodynamics of unpaired terminal nucleotides on short RNA helixes correlates with stacking at helix termini in larger RNAs.
    Journal of molecular biology, 1999, Jul-30, Volume: 290, Issue:5

    Topics: Adenine; Animals; Base Pair Mismatch; Base Pairing; Base Sequence; Crystallization; Crystallography, X-Ray; Databases, Factual; Guanine; Hydrogen Bonding; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Pyrimidinones; Ribonucleotides; RNA; Static Electricity; Thermodynamics

1999
Facile synthesis of N-(1-alkenyl) derivatives of 2,4-pyrimidinediones.
    Nucleosides, nucleotides & nucleic acids, 2000, Volume: 19, Issue:7

    Topics: Adenine; Aldehydes; Antiviral Agents; Imidoesters; Mesylates; Nucleotides; Pyrimidinones; Trimethylsilyl Compounds

2000
Looking down the drug pipeline.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1998, Volume: 12, Issue:3

    Topics: Adenine; Animals; Anti-HIV Agents; Biological Availability; Chlorobenzenes; Clinical Trials as Topic; Codon; Dideoxyadenosine; Drug Resistance, Microbial; Drugs, Investigational; Granulocyte-Macrophage Colony-Stimulating Factor; HIV Infections; HIV Protease Inhibitors; Humans; Naphthalenes; Organophosphonates; Pyrimidinones; Receptors, CCR5; Receptors, CXCR4; Reverse Transcriptase Inhibitors; Tenofovir

1998
New drugs in development.
    Project Inform perspective, 1998, Issue:25

    Topics: Adenine; Alkynes; Anti-HIV Agents; Benzoxazines; Carbamates; CD4 Lymphocyte Count; Clinical Trials as Topic; Cyclopropanes; Dideoxynucleosides; Drug Therapy, Combination; Drugs, Investigational; Furans; HIV Infections; HIV Protease Inhibitors; Humans; Imidazoles; Kidney Diseases; Lopinavir; Oxazines; Pyridines; Pyrimidinones; Reverse Transcriptase Inhibitors; Sulfonamides; Viral Load

1998
Upcoming compassionate use programs for two new antiretrovirals will begin this fall.
    STEP perspective, 1999,Fall, Volume: 99, Issue:3

    Topics: Adenine; Anti-HIV Agents; Clinical Trials as Topic; Drug Approval; HIV Infections; HIV Protease Inhibitors; Humans; Lopinavir; Organophosphonates; Organophosphorus Compounds; Patient Selection; Pyrimidinones; Reverse Transcriptase Inhibitors; Tenofovir

1999
Expanded access.
    Project Inform perspective, 1999, Issue:28

    Topics: Adenine; Anti-HIV Agents; Drug Approval; Drugs, Investigational; Health Services Accessibility; HIV Infections; HIV Protease Inhibitors; Humans; Lopinavir; Organophosphonates; Organophosphorus Compounds; Pyrimidinones; Reverse Transcriptase Inhibitors; Tenofovir

1999
Adsorption of monomers on microspherical structures of thermal heterocomplex molecules from amino acids.
    Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life, 1995, Volume: 25, Issue:5

    Topics: Adenine; Adsorption; Amino Acids; Aspartic Acid; Evolution, Chemical; Histidine; Hot Temperature; Hydrogen-Ion Concentration; Microspheres; Nucleosides; Proline; Pyrimidinones; Static Electricity; Suspensions

1995
Antiretroviral news from ICAAC 2000.
    The Hopkins HIV report : a bimonthly newsletter for healthcare providers, 2000, Volume: 12, Issue:5

    Topics: Adenine; Antiretroviral Therapy, Highly Active; Drug Administration Schedule; Drug Resistance; HIV Infections; Humans; Lopinavir; Organophosphonates; Organophosphorus Compounds; Pyrimidinones; Ritonavir; Tenofovir

2000
Tenofovir-related Fanconi syndrome with nephrogenic diabetes insipidus in a patient with acquired immunodeficiency syndrome: the role of lopinavir-ritonavir-didanosine.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2003, Dec-15, Volume: 37, Issue:12

    Topics: Acquired Immunodeficiency Syndrome; Adenine; Adult; Anti-HIV Agents; Diabetes Insipidus, Nephrogenic; Didanosine; Drug Therapy, Combination; Fanconi Syndrome; Humans; Lopinavir; Male; Organophosphonates; Organophosphorus Compounds; Pyrimidinones; Ritonavir; Tenofovir

2003
French investigators warn of LPV/TDF/ddI interaction.
    IAPAC monthly, 2003, Volume: 9, Issue:12

    Topics: Adenine; CD4 Lymphocyte Count; Didanosine; HIV Infections; HIV Protease Inhibitors; Humans; Lopinavir; Organophosphonates; Organophosphorus Compounds; Pyrimidinones; Reverse Transcriptase Inhibitors; Tenofovir; Viral Load

2003
The fidelity of replication of the three-base-pair set adenine/thymine, hypoxanthine/cytosine and 6-thiopurine/5-methyl-2-pyrimidinone with T7 DNA polymerase.
    The Biochemical journal, 2004, Aug-01, Volume: 381, Issue:Pt 3

    Topics: Adenine; Base Pairing; Cytosine; DNA Replication; DNA-Directed DNA Polymerase; Hypoxanthine; Kinetics; Mercaptopurine; Models, Genetic; Purines; Pyrimidinones; Research Design; Sensitivity and Specificity; Thymine

2004
Targeting the polyamine pathway with transition-state analogue inhibitors of 5'-methylthioadenosine phosphorylase.
    Journal of medicinal chemistry, 2004, Jun-03, Volume: 47, Issue:12

    Topics: Adenine; Humans; Polyamines; Purine Nucleosides; Purine-Nucleoside Phosphorylase; Pyrimidinones; Pyrroles; Pyrrolidines; Stereoisomerism; Structure-Activity Relationship

2004
[5 years' data are convincing. Lopinavir as primary therapy is effective and safe in the long term].
    MMW Fortschritte der Medizin, 2004, Apr-26, Volume: 146 Spec No 1

    Topics: Adenine; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Clinical Trials as Topic; Cyclopropanes; Drug Synergism; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Long-Term Care; Lopinavir; Organophosphonates; Oxazines; Pyrimidinones; Ritonavir; Tenofovir; Viral Load

2004
Selection of a rare resistance profile in an HIV-1-infected patient exhibiting a failure to an antiretroviral regimen including tenofovir DF.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2005, Volume: 32, Issue:3

    Topics: Adenine; Adult; Anti-HIV Agents; Didanosine; Dideoxynucleosides; Drug Resistance, Viral; Female; Gabon; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Lopinavir; Microbial Sensitivity Tests; Mutation; Organophosphonates; Pyrimidinones; Tenofovir; Viral Load

2005
Serum hypophosphatemia in tenofovir disoproxil fumarate recipients is multifactorial in origin, questioning the utility of its monitoring in clinical practice.
    Journal of acquired immune deficiency syndromes (1999), 2005, Mar-01, Volume: 38, Issue:3

    Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Blood Chemical Analysis; Creatinine; Fanconi Syndrome; Female; HIV Infections; Humans; Hypophosphatemia; Lopinavir; Male; Organophosphonates; Phosphates; Prospective Studies; Pyrimidinones; Reproducibility of Results; Tenofovir; Urea

2005
Nephrotoxicity in a child with perinatal HIV on tenofovir, didanosine and lopinavir/ritonavir.
    Pediatric nephrology (Berlin, Germany), 2006, Volume: 21, Issue:7

    Topics: Adenine; Anti-HIV Agents; Child; Diabetes Insipidus, Nephrogenic; Didanosine; Drug Therapy, Combination; Fanconi Syndrome; Female; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Kidney; Kidney Diseases; Lopinavir; Organophosphonates; Pregnancy; Pregnancy Complications; Pyrimidinones; Ritonavir; Tenofovir

2006
Urinary beta2-microglobulin as a possible sensitive marker for renal injury caused by tenofovir disoproxil fumarate.
    AIDS research and human retroviruses, 2006, Volume: 22, Issue:8

    Topics: Adenine; Adult; Anti-HIV Agents; beta 2-Microglobulin; Biomarkers; Creatinine; Female; HIV Infections; HIV-1; Humans; Kidney Tubules; Lopinavir; Male; Middle Aged; Organophosphonates; Pyrimidinones; Tenofovir; Thinness

2006
In vitro cytotoxicity and mitochondrial toxicity of tenofovir alone and in combination with other antiretrovirals in human renal proximal tubule cells.
    Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:11

    Topics: Adenine; Anti-HIV Agents; Cell Survival; Cells, Cultured; Didanosine; DNA, Mitochondrial; Drug Interactions; Electron Transport Complex IV; Humans; Kidney Tubules, Proximal; Lopinavir; Mitochondria; Organophosphonates; Pyrimidinones; Ritonavir; RNA; Tenofovir; Zidovudine

2006
Progressive multifocal leukoencephalopathy: serial high-b-value diffusion-weighted MR imaging and apparent diffusion coefficient measurements to assess response to highly active antiretroviral therapy.
    AJNR. American journal of neuroradiology, 2007, Volume: 28, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Brain; Diffusion; Diffusion Magnetic Resonance Imaging; HIV Protease Inhibitors; Humans; Leukoencephalopathy, Progressive Multifocal; Lopinavir; Male; Organophosphonates; Pyrimidinones; Ritonavir; Tenofovir; Zidovudine

2007
Induction therapy with enfuvirtide-based highly active antiretroviral therapy in a patient with acute HIV-1 infection.
    AIDS patient care and STDs, 2007, Volume: 21, Issue:2

    Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Deoxycytidine; Emtricitabine; Enfuvirtide; HIV Envelope Protein gp41; HIV Infections; HIV-1; Humans; Lopinavir; Male; Organophosphonates; Peptide Fragments; Pyrimidinones; Ritonavir; Tenofovir; Viral Load; Viremia

2007
Transmission of multidrug-resistant HIV-1: 5 years of immunological and virological survey.
    AIDS (London, England), 2007, Jun-19, Volume: 21, Issue:10

    Topics: Adenine; Anti-Retroviral Agents; CD4 Lymphocyte Count; Drug Resistance, Multiple, Viral; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Lopinavir; Mutation; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Tenofovir; Viral Load

2007
HPV oral infection. Case report of an HIV-positive Nigerian sex worker.
    Le infezioni in medicina, 2007, Volume: 15, Issue:2

    Topics: Adenine; Adult; Alphapapillomavirus; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Deoxycytidine; Dideoxynucleosides; Emtricitabine; Female; HIV Infections; Humans; Italy; Lamivudine; Lopinavir; Mouth Mucosa; Nigeria; Organophosphonates; Papillomavirus Infections; Pyrimidinones; Ritonavir; Sex Work; Stomatitis; Tenofovir; Treatment Refusal; Zidovudine

2007
Lopinavir-ritonavir dramatically affects the pharmacokinetics of irinotecan in HIV patients with Kaposi's sarcoma.
    Clinical pharmacology and therapeutics, 2008, Volume: 83, Issue:4

    Topics: Adenine; Adult; Aged; Anti-HIV Agents; Antineoplastic Agents, Phytogenic; Antiretroviral Therapy, Highly Active; Area Under Curve; Camptothecin; Drug Therapy, Combination; HIV Infections; Humans; Irinotecan; Lamivudine; Lopinavir; Male; Middle Aged; Organophosphonates; Pyrimidinones; Ritonavir; Sarcoma, Kaposi; Tenofovir; White People

2008
Antiretroviral drug exposure in the female genital tract: implications for oral pre- and post-exposure prophylaxis.
    AIDS (London, England), 2007, Sep-12, Volume: 21, Issue:14

    Topics: Adenine; Administration, Oral; Adult; Alkynes; Anti-Retroviral Agents; Atazanavir Sulfate; Benzoxazines; Cyclopropanes; Deoxycytidine; Drug Therapy, Combination; Emtricitabine; Female; Genitalia, Female; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Lopinavir; Oligopeptides; Organophosphonates; Pyridines; Pyrimidinones; Reverse Transcriptase Inhibitors; Tenofovir; Zidovudine

2007
[New German and American guidelines for therapy of hepatitis B. Discrepancies and similarities].
    Medizinische Klinik (Munich, Germany : 1983), 2007, Sep-15, Volume: 102, Issue:9

    Topics: Adenine; Alanine Transaminase; Antiviral Agents; Biopsy; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Germany; Guanine; Hepatitis B; Humans; Lamivudine; Liver; Liver Cirrhosis; Nucleosides; Organophosphonates; Practice Guidelines as Topic; Pyrimidinones; Telbivudine; Thymidine; United States

2007
Summaries for patients. Antiviral therapy for chronic hepatitis B.
    Annals of internal medicine, 2007, Dec-04, Volume: 147, Issue:11

    Topics: Adenine; Adolescent; Adult; Aged; Antiviral Agents; Biomarkers; DNA, Viral; Drug Therapy, Combination; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Thymidine; Viral Load

2007
[Anti-viral therapy of type B chronic hepatitis. 3. Future of anti-viral agents].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2008, Jan-10, Volume: 97, Issue:1

    Topics: Adenine; Antiviral Agents; Deoxycytidine; Drug Resistance, Viral; Emtricitabine; Hepatitis B, Chronic; Humans; Interferons; Nucleic Acid Synthesis Inhibitors; Nucleosides; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine

2008
Lack of evidence for an effect of lopinavir/ritonavir on tenofovir renal clearance.
    Clinical pharmacology and therapeutics, 2008, Volume: 84, Issue:6

    Topics: Adenine; Creatinine; Drug Interactions; Drug Therapy, Combination; Female; Glomerular Filtration Rate; HIV Infections; HIV Protease Inhibitors; Humans; Kidney Tubules; Lopinavir; Male; Organophosphonates; Pyrimidinones; Ritonavir; Sensitivity and Specificity; Tenofovir

2008
Telbivudine, a nucleoside analog inhibitor of HBV polymerase, has a different in vitro cross-resistance profile than the nucleotide analog inhibitors adefovir and tenofovir.
    Antiviral research, 2009, Volume: 81, Issue:2

    Topics: Adenine; Amino Acid Substitution; Antiviral Agents; Cell Line, Tumor; Drug Resistance, Viral; Gene Products, pol; Hepatitis B virus; Humans; Microbial Sensitivity Tests; Mutation, Missense; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine

2009
96-week CASTLE data show similar efficacy results.
    AIDS patient care and STDs, 2008, Volume: 22, Issue:11

    Topics: Adenine; Anti-HIV Agents; Atazanavir Sulfate; Deoxycytidine; Drug Therapy, Combination; Emtricitabine; HIV Infections; HIV-1; Humans; Lopinavir; Multicenter Studies as Topic; Oligopeptides; Organophosphonates; Pyridines; Pyrimidinones; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Ritonavir; Tenofovir; Treatment Outcome; Viral Load

2008
Interactions of the "piano-stool" [ruthenium(II) (eta6-arene)(en)CL]+ complexes with water and nucleobases; ab initio and DFT study.
    Journal of computational chemistry, 2009, Volume: 30, Issue:12

    Topics: Adenine; Antineoplastic Agents; Binding Sites; Cytosine; Ethylenediamines; Guanine; Models, Molecular; Molecular Structure; Purines; Pyrimidinones; Quantum Theory; Ruthenium; Thermodynamics; Thymine; Uracil; Water

2009
[Atazanavir-induced nephrolithiasis].
    Enfermedades infecciosas y microbiologia clinica, 2009, Volume: 27, Issue:2

    Topics: Adenine; Adult; Alkynes; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Hepatitis B, Chronic; Hepatitis C, Chronic; Hepatitis D, Chronic; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Lopinavir; Male; Nephrolithiasis; Oligopeptides; Organophosphonates; Pyridines; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; Stavudine; Tenofovir

2009
The rtA194T polymerase mutation impacts viral replication and susceptibility to tenofovir in hepatitis B e antigen-positive and hepatitis B e antigen-negative hepatitis B virus strains.
    Hepatology (Baltimore, Md.), 2009, Volume: 49, Issue:4

    Topics: Adenine; Anti-HIV Agents; Cell Line, Tumor; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Guanine; Hepatitis B; Hepatitis B e Antigens; Hepatitis B virus; Humans; Lamivudine; Mutation; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Viral Proteins; Virus Replication

2009
Mitochondrial function, morphology and metabolic parameters improve after switching from stavudine to a tenofovir-containing regimen.
    The Journal of antimicrobial chemotherapy, 2009, Volume: 63, Issue:6

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenine; Adipose Tissue; Adult; Anti-HIV Agents; Body Fat Distribution; CD4 Lymphocyte Count; Deoxyguanosine; F2-Isoprostanes; Glutathione; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Lamivudine; Lopinavir; Male; Mitochondria; Organophosphonates; Pyrimidinones; Ritonavir; Stavudine; Tenofovir; Treatment Outcome; Viral Load

2009
FDA approves three generics.
    AIDS patient care and STDs, 2009, Volume: 23, Issue:4

    Topics: Adenine; Anti-HIV Agents; Drug Approval; Drugs, Generic; HIV Infections; Humans; Lamivudine; Lopinavir; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; Tenofovir; United States; United States Food and Drug Administration

2009
Anti-hepatitis B virus activity in vitro of combinations of tenofovir with nucleoside/nucleotide analogues.
    Antiviral chemistry & chemotherapy, 2009, Volume: 19, Issue:4

    Topics: Adenine; Antiviral Agents; Cell Line; Cell Survival; Deoxycytidine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Emtricitabine; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Nucleotides; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine

2009
Different models of HBeAg seroconversion predicated by on-treatment ALT and HBV DNA profiles.
    Journal of viral hepatitis, 2009, Volume: 16, Issue:12

    Topics: Adenine; Adult; Aged; Alanine Transaminase; Antiviral Agents; DNA, Viral; Female; Follow-Up Studies; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Nucleosides; Organophosphonates; Prognosis; Pyrimidinones; Retrospective Studies; Telbivudine; Thymidine; Young Adult

2009
Hepatitis B in HIV patients: what is the current treatment and what are the challenges?
    Journal of HIV therapy, 2009, Volume: 14, Issue:1

    Topics: Adenine; Antiviral Agents; Deoxycytidine; DNA, Viral; Drug Therapy, Combination; Emtricitabine; Guanine; Hepatitis B Surface Antigens; Hepatitis B, Chronic; HIV Infections; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Liver Cirrhosis; Nucleosides; Organophosphonates; Polyethylene Glycols; Pyrimidinones; Recombinant Proteins; Telbivudine; Tenofovir; Thymidine; Transaminases

2009
[Medication change due to side effects or possible long-term complications. Side effect management with vision].
    MMW Fortschritte der Medizin, 2009, Apr-30, Volume: 151, Issue:18

    Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Deoxycytidine; Drug Combinations; Efavirenz, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; HIV Infections; HIV-1; Humans; Long-Term Care; Lopinavir; Oligopeptides; Organophosphonates; Oxazines; Pyridines; Pyrimidinones; Pyrrolidinones; Raltegravir Potassium; Randomized Controlled Trials as Topic

2009
[Telbivudine in the management of HIV/HBV coinfection. Treating hepatitis B without HIV trouble].
    MMW Fortschritte der Medizin, 2009, Apr-30, Volume: 151, Issue:18

    Topics: Adenine; AIDS-Related Opportunistic Infections; Algorithms; Anti-HIV Agents; Antiviral Agents; Comorbidity; DNA, Viral; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; Hepatitis B virus; Hepatitis B, Chronic; Humans; Liver Function Tests; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Thymidine

2009
[The efficacy of nucleoside/nucleotide analogue on chronic hepatitis B].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2009, Volume: 17, Issue:10

    Topics: Adenine; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine; Treatment Outcome; Virus Replication

2009
Treatment modification in human immunodeficiency virus-infected individuals starting combination antiretroviral therapy between 2005 and 2008.
    Archives of internal medicine, 2010, Jan-11, Volume: 170, Issue:1

    Topics: Adenine; Adult; AIDS-Related Opportunistic Infections; Alkynes; Anti-HIV Agents; Atazanavir Sulfate; Benzoxazines; Cyclopropanes; Deoxycytidine; Dideoxynucleosides; Drug Therapy, Combination; Emtricitabine; Female; HIV Infections; Humans; Lamivudine; Lopinavir; Male; Middle Aged; Nevirapine; Oligopeptides; Organophosphonates; Proportional Hazards Models; Prospective Studies; Pyridines; Pyrimidinones; Risk Factors; Switzerland; Tenofovir; Zidovudine

2010
DAART for human immunodeficiency virus-infected patients: Studying subjects not at risk for nonadherence and use of untested interventions.
    Archives of internal medicine, 2010, Jan-11, Volume: 170, Issue:1

    Topics: Adenine; Administration, Oral; Adolescent; Adult; Aged; Anti-HIV Agents; Deoxycytidine; Dose-Response Relationship, Drug; Drug Resistance, Viral; Emtricitabine; Female; Genotype; HIV Infections; HIV-1; Humans; Lopinavir; Male; Middle Aged; Organophosphonates; Patient Compliance; Pyrimidinones; Randomized Controlled Trials as Topic; RNA, Viral; Stavudine; Tenofovir; Treatment Outcome; Young Adult

2010
Cost-effectiveness analysis of roadmap models in chronic hepatitis B using tenofovir as the rescue therapy.
    Antiviral therapy, 2010, Volume: 15, Issue:2

    Topics: Adenine; Antiviral Agents; Asia; Cost-Benefit Analysis; Decision Support Techniques; DNA, Viral; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; Germany; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Models, Economic; Nucleosides; Organophosphonates; Pyrimidinones; Salvage Therapy; Telbivudine; Tenofovir; Thymidine; Treatment Outcome; United States

2010
Viral resistance in hepatitis B: prevalence and management.
    Current gastroenterology reports, 2010, Volume: 12, Issue:1

    Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Genetic Testing; Genotype; Guanine; Hepatitis B; Humans; Lamivudine; Nucleosides; Organophosphonates; Phenotype; Pyrimidinones; Telbivudine; Tenofovir; Thymidine

2010
Evaluation of the in vitro anti-HBV activity of clevudine in combination with other nucleoside/nucleotide inhibitors.
    Antiviral therapy, 2010, Volume: 15, Issue:3

    Topics: Adenine; Anti-HIV Agents; Antiviral Agents; Arabinofuranosyluracil; Cell Line; Cells, Cultured; Drug Antagonism; Drug Synergism; Drug Therapy, Combination; Guanine; Hepatitis B virus; Hepatocytes; Humans; Lamivudine; Microbial Sensitivity Tests; Nucleosides; Nucleotides; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine

2010
Cost-effectiveness of nucleoside analog therapy for hepatitis B in China: a Markov analysis.
    Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 2010, Volume: 13, Issue:5

    Topics: Adenine; Antiviral Agents; China; Cost-Benefit Analysis; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Markov Chains; Models, Economic; Models, Statistical; Monte Carlo Method; Nucleosides; Organophosphonates; Pyrimidinones; Quality-Adjusted Life Years; Reverse Transcriptase Inhibitors; Serologic Tests; Telbivudine; Thymidine

2010
Cancer-derived mutations in the regulatory subunit p85alpha of phosphoinositide 3-kinase function through the catalytic subunit p110alpha.
    Proceedings of the National Academy of Sciences of the United States of America, 2010, Aug-31, Volume: 107, Issue:35

    Topics: Adenine; Amino Acid Sequence; Animals; Base Sequence; Blotting, Western; Catalytic Domain; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Chick Embryo; Class I Phosphatidylinositol 3-Kinases; Dioxoles; Fibroblasts; Humans; Immunoprecipitation; Morpholines; Mutation; Neoplasms; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Binding; Protein Subunits; Pyrimidinones; Quinazolines; Thiazolidinediones; Transfection

2010
Tolerability of HIV postexposure prophylaxis with tenofovir/emtricitabine and lopinavir/ritonavir tablet formulation.
    AIDS (London, England), 2010, Sep-24, Volume: 24, Issue:15

    Topics: Adenine; Adolescent; Adult; Antiviral Agents; CD4 Lymphocyte Count; Deoxycytidine; Emtricitabine; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lopinavir; Male; Organophosphonates; Post-Exposure Prophylaxis; Practice Guidelines as Topic; Pyrimidinones; Ritonavir; RNA, Viral; Tenofovir; Treatment Outcome; Young Adult

2010
[Two cases of Fanconi's syndrome induced by tenofovir in the Ivory Coast].
    Medecine et maladies infectieuses, 2011, Volume: 41, Issue:2

    Topics: Adenine; Aged; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cote d'Ivoire; Cyclopropanes; Drug Therapy, Combination; Enterobacter aerogenes; Enterobacteriaceae Infections; Fanconi Syndrome; Female; HIV Infections; HIV-1; Humans; Lamivudine; Lopinavir; Malaria; Male; Middle Aged; Organophosphonates; Pyelonephritis; Pyrimidinones; Ritonavir; Tenofovir

2011
[Analogs combination therapy in chronic hepatitis B: when and how?].
    Gastroenterologie clinique et biologique, 2010, Volume: 34 Suppl 2

    Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine

2010
[Long-term therapy for chronic hepatitis B in HIV co-infected patients].
    Gastroenterologie clinique et biologique, 2010, Volume: 34 Suppl 2

    Topics: Adenine; Antiretroviral Therapy, Highly Active; Antiviral Agents; Deoxycytidine; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine; Guanine; Hepatitis B, Chronic; HIV Infections; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Recombinant Proteins; Telbivudine; Tenofovir; Thymidine

2010
Profile of HBV antiviral resistance mutations with distinct evolutionary pathways against nucleoside/nucleotide analogue treatment among Chinese chronic hepatitis B patients.
    Antiviral therapy, 2010, Volume: 15, Issue:8

    Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; China; Cross-Sectional Studies; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Molecular Typing; Mutation, Missense; Nucleosides; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Thymidine; Young Adult

2010
Treatment of HBeAg-negative chronic hepatitis B patients with nucleos(t)ide analogues.
    Liver international : official journal of the International Association for the Study of the Liver, 2011, Volume: 31 Suppl 1

    Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Time Factors; Treatment Outcome

2011
Cost effectiveness of atazanavir-ritonavir versus lopinavir-ritonavir in treatment-naïve human immunodeficiency virus-infected patients in the United States.
    Journal of medical economics, 2011, Volume: 14, Issue:2

    Topics: Adenine; Adult; Anti-HIV Agents; Atazanavir Sulfate; CD4 Lymphocyte Count; Cost-Benefit Analysis; Deoxycytidine; Drug Therapy, Combination; Emtricitabine; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lopinavir; Male; Markov Chains; Oligopeptides; Organophosphonates; Pyridines; Pyrimidinones; Quality-Adjusted Life Years; Reverse Transcriptase Inhibitors; Risk Assessment; Ritonavir; Tenofovir; United States

2011
Phosphatidylinositol 3-kinase isoform-specific effects in airway mesenchymal cell function.
    The Journal of pharmacology and experimental therapeutics, 2011, Volume: 337, Issue:2

    Topics: Adenine; Blotting, Western; Extracellular Matrix; Fibroblasts; Fibronectins; Humans; Hydrazones; Interleukin-6; Isoenzymes; Mesenchymal Stem Cells; Mitochondria; Morpholines; Muscle, Smooth; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Pyrimidinones; Quinazolines; Respiratory System; Substrate Specificity; Sulfonamides; Transforming Growth Factor beta; Vascular Endothelial Growth Factor A

2011
Genotypic resistance profile of hepatitis B virus (HBV) in a large cohort of nucleos(t)ide analogue-experienced Chinese patients with chronic HBV infection.
    Journal of viral hepatitis, 2011, Volume: 18, Issue:4

    Topics: Adenine; Adult; Amino Acid Substitution; Antiviral Agents; China; DNA, Viral; Drug Resistance, Viral; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Molecular Sequence Data; Mutation, Missense; Nucleosides; Organophosphonates; Pyrimidinones; RNA-Directed DNA Polymerase; Sequence Analysis, DNA; Telbivudine; Thymidine; Viral Proteins

2011
Two patterns of alanine aminotransferase increase to predict long-term viral response in chronic hepatitis B patients: virus- or host-induced?
    Antiviral therapy, 2011, Volume: 16, Issue:3

    Topics: Adenine; Adult; Aged; Alanine Transaminase; Antiviral Agents; DNA, Viral; Female; Guanine; Hepacivirus; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interferon-gamma; Lamivudine; Male; Middle Aged; Nucleosides; Organophosphonates; Predictive Value of Tests; Pyrimidinones; T-Lymphocytes; Telbivudine; Thymidine; Treatment Outcome; Up-Regulation; Young Adult

2011
Antiretroviral therapy alone resulted in successful resolution of large idiopathic esophageal ulcers in a patient with acute retroviral syndrome.
    AIDS (London, England), 2011, Aug-24, Volume: 25, Issue:13

    Topics: Adenine; Adult; Anti-HIV Agents; Antiviral Agents; Deoxycytidine; Drug Therapy, Combination; Emtricitabine; Esophageal Diseases; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lopinavir; Male; Organophosphonates; Pyrimidinones; Ritonavir; RNA, Viral; Syndrome; Tenofovir; Ulcer

2011
Unraveling the structural complexity in a single-stranded RNA tail: implications for efficient ligand binding in the prequeuosine riboswitch.
    Nucleic acids research, 2012, Volume: 40, Issue:3

    Topics: Adenine; Ligands; Molecular Dynamics Simulation; Mutation; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Pyrimidinones; Pyrroles; Riboswitch; RNA; RNA Stability

2012
[New drugs of treatment of patients with chronic hepatitis B].
    Nihon rinsho. Japanese journal of clinical medicine, 2011, Volume: 69 Suppl 4

    Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Deoxycytidine; Emtricitabine; Hepatitis B, Chronic; Humans; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine

2011
Development of a combination microbicide gel formulation containing IQP-0528 and tenofovir for the prevention of HIV infection.
    Journal of pharmaceutical sciences, 2012, Volume: 101, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adenine; Anti-HIV Agents; Anti-Infective Agents; Cell Line; Chemistry, Pharmaceutical; Excipients; Gels; HIV-1; Humans; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Solubility; Tenofovir; Viscosity

2012
Current practice of chronic hepatitis B treatment in Southern Italy.
    European journal of internal medicine, 2012, Volume: 23, Issue:5

    Topics: Adenine; Adult; Age Factors; Aged; Aged, 80 and over; Antiviral Agents; Female; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interferon-alpha; Italy; Lamivudine; Male; Middle Aged; Nucleosides; Organophosphonates; Polyethylene Glycols; Practice Patterns, Physicians'; Pyrimidinones; Recombinant Proteins; Telbivudine; Tenofovir; Thymidine; Young Adult

2012
Gas-phase hydration thermochemistry of sodiated and potassiated nucleic acid bases.
    Journal of the American Society for Mass Spectrometry, 2012, Volume: 23, Issue:9

    Topics: Adenine; Cytosine; Gases; Mass Spectrometry; Potassium; Pyrimidinones; Sodium; Thermodynamics; Thymine; Uracil

2012
Safety and efficacy of tenofovir/IQP-0528 combination gels - a dual compartment microbicide for HIV-1 prevention.
    Antiviral research, 2012, Volume: 96, Issue:2

    Topics: Adenine; Administration, Mucosal; Anti-Infective Agents; Cell Line; Cell Survival; Chemoprevention; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Organophosphonates; Pyrimidinones; Tenofovir; Tissue Culture Techniques; Vaginal Creams, Foams, and Jellies

2012
Screening study on hemolysis suppression effect of an alternative plasticizer for the development of a novel blood container made of polyvinyl chloride.
    Journal of biomedical materials research. Part B, Applied biomaterials, 2014, Volume: 102, Issue:4

    Topics: Adenine; Benzoates; Blood Preservation; Citrates; Cyclohexanecarboxylic Acids; Depression, Chemical; Dicarboxylic Acids; Diethylhexyl Phthalate; Gas Chromatography-Mass Spectrometry; Glucose; Hemolysis; Heparin; Humans; Inosine Nucleotides; Mannitol; Oxazoles; Plasticizers; Polyvinyl Chloride; Pyrimidinones; Structure-Activity Relationship

2014
Profound blockade of T cell activation requires concomitant inhibition of different class I PI3K isoforms.
    Immunologic research, 2015, Volume: 62, Issue:2

    Topics: Adenine; Apoptosis; Cell Differentiation; Class I Phosphatidylinositol 3-Kinases; Cytokines; Enzyme Inhibitors; Humans; Immunophenotyping; Inhibitory Concentration 50; Isoenzymes; Lymphocyte Activation; Morpholines; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyrimidinones; Quinazolines; T-Lymphocytes

2015
Immucillins Impair Leishmania (L.) infantum chagasi and Leishmania (L.) amazonensis Multiplication In Vitro.
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Adenine; Adenosine; Animals; Antiprotozoal Agents; Cell Proliferation; Enzyme Inhibitors; Female; Humans; In Vitro Techniques; Kinetics; Leishmania infantum; Leishmania mexicana; Leishmaniasis, Cutaneous; Leishmaniasis, Visceral; Mice; Mice, Inbred BALB C; Microscopy, Electron, Transmission; N-Glycosyl Hydrolases; Purine Nucleosides; Pyrimidinones; Pyrroles; Pyrrolidines

2015
Immucillins ImmA and ImmH Are Effective and Non-toxic in the Treatment of Experimental Visceral Leishmaniasis.
    PLoS neglected tropical diseases, 2015, Volume: 9, Issue:12

    Topics: Adenine; Adenosine; Animals; Antibodies, Protozoan; Antiprotozoal Agents; Blood Chemical Analysis; Disease Models, Animal; Drug-Related Side Effects and Adverse Reactions; Female; Gene Expression; Immunophenotyping; Interferon-gamma; Interleukin-10; Leishmania; Leishmaniasis, Visceral; Leukocytes, Mononuclear; Mesocricetus; Mice, Inbred BALB C; Parasite Load; Purine Nucleosides; Pyrimidinones; Pyrrolidines; Spleen; T-Lymphocyte Subsets; Treatment Outcome; Tumor Necrosis Factor-alpha

2015
Reliable vibrational wavenumbers for C=O and N-H stretchings of isolated and hydrogen-bonded nucleic acid bases.
    Physical chemistry chemical physics : PCCP, 2016, Mar-28, Volume: 18, Issue:12

    Topics: Adenine; Base Pairing; Cytosine; Dimerization; Guanine; Hydrogen; Hydrogen Bonding; Models, Molecular; Nitrogen; Nucleic Acids; Oxygen; Pyrimidinones; Spectrophotometry, Infrared; Thymine; Uracil

2016
Phosphoinositide-3-kinase inhibition elevates ferritin level resulting depletion of labile iron pool and blocking of glioma cell proliferation.
    Biochimica et biophysica acta. General subjects, 2019, Volume: 1863, Issue:3

    Topics: Adenine; Animals; Brain Neoplasms; Cell Proliferation; Cells, Cultured; Chromones; Down-Regulation; Ferritins; Glioma; Humans; Iron; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Pyrimidinones; Quinazolines; Rats; Thiazolidinediones; Up-Regulation

2019
Inhibition of human UDP-glucuronosyltransferase (UGT) enzymes by kinase inhibitors: Effects of dabrafenib, ibrutinib, nintedanib, trametinib and BIBF 1202.
    Biochemical pharmacology, 2019, Volume: 169

    Topics: Adenine; Glucuronosyltransferase; Humans; Imidazoles; Indoles; Microsomes, Liver; Oximes; Piperidines; Protein Kinase Inhibitors; Pyrazoles; Pyridones; Pyrimidines; Pyrimidinones

2019
Quantum chemical and well-tempered metadynamics study to design adenine analogs for orthogonal Preq
    Journal of biomolecular structure & dynamics, 2020, Volume: 38, Issue:15

    Topics: Adenine; Nucleic Acid Conformation; Pyrimidinones; Pyrroles; Riboswitch

2020
Synthesis of Piperidine Nucleosides as Conformationally Restricted Immucillin Mimics.
    Molecules (Basel, Switzerland), 2021, Mar-16, Volume: 26, Issue:6

    Topics: Adenine; Adenosine; Magnetic Resonance Spectroscopy; Molecular Conformation; Nucleosides; Piperidines; Purine Nucleosides; Pyrimidinones; Pyrrolidines; Structure-Activity Relationship

2021