adenine has been researched along with phosphoribosyl pyrophosphate in 62 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 49 (79.03) | 18.7374 |
1990's | 5 (8.06) | 18.2507 |
2000's | 6 (9.68) | 29.6817 |
2010's | 1 (1.61) | 24.3611 |
2020's | 1 (1.61) | 2.80 |
Authors | Studies |
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Emmerson, BT; Gordon, RB; Johnson, LA; Thompson, L | 2 |
Gerlach, E; Steinkopff, G; Zimmer, HG | 1 |
Boer, P; Brosh, S; de Vries, A; Elazar, E; Pinkhas, J; Sperling, O; Szeinberg, A | 1 |
Gerlach, E; Zimmer, HG | 1 |
Allison, AC; Hovi, T; Raivio, K; Vaheri, A | 1 |
Boer, P; Lipstein, B; Sperling, O | 1 |
Bobyk, MA; Butukhanov, VD; Kulaev, IS; Tsyrenov, VZh | 1 |
Cohen, A; Gudas, LJ; Martin, DW; Ullman, B | 1 |
Akkerman, JW; De Bree, PK; De Bruyn, CH; Siegenbeek Van Heukelom, LH; Staal, GE; Stoop, JW; Wadman, SK; Zegers, BJ | 1 |
de Bruyn, CH; Oei, TL | 1 |
Battell, ML; Henderson, JF; Khoo, MK; Zombor, G | 1 |
Cox, RP; Holland, MJ; Klein, NC | 1 |
Hershfield, MS; Seegmiller, JE; Snyder, FF | 2 |
Hershfield, MS; Seegmiller, JE; Spector, EB | 1 |
Hershfield, MS; Seegmiller, JE | 2 |
Molnár, J | 1 |
Buttin, G; Debatisse, M | 1 |
Seegmiller, JE; Skaper, SD | 1 |
Badenoch-Jones, P; Buttery, PJ | 1 |
Henderson, JF; Smith, CM; Snyder, FF; Zombor, G | 1 |
Chilson, OP | 1 |
Bowditch, J; Brown, AK; Dow, JW; Raeside, DL | 1 |
Barankiewicz, J; Cohen, A | 2 |
Chalmers, AH; Coleman, M; Marshall, VR; Mohan Rao, M; Rotstein, T | 1 |
Fairbanks, LD; Simmonds, HA; Webster, DR | 1 |
Balis, ME; Xu, YL; Yip, LC | 1 |
Abe, S; Hayasaka, K; Koyama, H; Kudoh, M; Kurosu, S; Matsushita, K; Narisawa, K; Okada, G; Tada, K | 1 |
Bowditch, J; Brown, AK; Dow, JW; Nigdikar, SV | 1 |
Kamatani, N; Miyamoto, T; Nishida, Y; Takeuchi, F | 1 |
Cartier, PH | 1 |
Cortes, P; Levin, NW; Schoenberger, AM; Venkatachalam, KK; Verghese, CP | 1 |
Lafleur, F; Lalanne, M | 1 |
Oosterhof, A; Peters, GJ; Veerkamp, JH | 1 |
Shainberg, A; Sperling, O; Zoref-Shani, E | 1 |
Bieth, R; Warter, S | 1 |
Becker, MA; Dicker, P; Rozengurt, E | 1 |
Des Rosiers, C; Lalanne, M; Willemot, J | 1 |
Canellakis, ES; Vitkauskas, G | 1 |
Boer, P; Jerushalmy, Z; Patya, M; Sperling, O | 1 |
Cascante, M; Curto, R; Sorribas, A; Voit, EO | 1 |
Khattar, NH; Turker, MS | 1 |
Alfonzo, JD; Sahota, A; Taylor, MW | 1 |
Zimmer, HG | 1 |
Bromberg, Y; Feinstein, S; Frishberg, Y; Sperling, O; Zoref-Shani, E | 1 |
Barsotti, C; Ipata, PL; Tozzi, MG | 1 |
Barsotti, C; Ipata, PL | 1 |
Taniguchi, A | 1 |
CAMBRIA, A; GIUFFRIDA, AM; RICCERI, G | 1 |
OVERGAARD-HANSEN, K | 1 |
TARR, HL | 1 |
HENDERSON, JF; KHOO, MK | 2 |
ELLIS, DB; LEPAGE, GA | 1 |
Bryant, RE; Crawford, CR | 1 |
Jiménez, A; Pompejus, M; Revuelta, JL; Santos, MA | 1 |
Iulek, J; Silva, CH; Silva, M; Thiemann, OH | 1 |
Christoffersen, S; Hansen, MR; Jensen, KF; Jensen, KS; Kadziola, A; Mølgaard, A; Poulsen, JC | 1 |
Al-Tameemi, H; Beavers, WN; Bovermann, H; Boyd, JM; Kim, J; Norambuena, J; Parker, D; Skaar, EP | 1 |
4 review(s) available for adenine and phosphoribosyl pyrophosphate
Article | Year |
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Purine metabolism and control of cell proliferation.
Topics: Adenine; Adenosine; Animals; Avian Sarcoma Viruses; Calcium; Cell Division; Cell Transformation, Viral; Chick Embryo; Cyclic GMP; DNA; Fibroblasts; Glycine; Humans; Hypoxanthines; Lectins; Lipopolysaccharides; Lymphocytes; Mitogens; Phosphoribosyl Pyrophosphate; Purine Nucleotides; Ribose-Phosphate Pyrophosphokinase; Trypsin | 1977 |
Gout and the regulation of purine biosynthesis.
Topics: Adenine; Amidophosphoribosyltransferase; Cell Line; Gout; Guanine; Humans; Hypoxanthines; Kinetics; Phosphoribosyl Pyrophosphate; Purine Nucleotides; Purines | 1976 |
Significance of the 5-phosphoribosyl-1-pyrophosphate pool for cardiac purine and pyrimidine nucleotide synthesis: studies with ribose, adenine, inosine, and orotic acid in rats.
Topics: Adenine; Animals; Inosine; Myocardium; Orotic Acid; Phosphoribosyl Pyrophosphate; Purine Nucleotides; Pyrimidine Nucleotides; Rats; Ribose | 1998 |
[Adenine phosphoribosyltransferase (APRT)].
Topics: Adenine; Adenine Phosphoribosyltransferase; Amino Acid Sequence; Animals; Catalysis; DNA; Humans; Phosphoribosyl Pyrophosphate; Purine Nucleotides; Urinary Calculi | 2003 |
58 other study(ies) available for adenine and phosphoribosyl pyrophosphate
Article | Year |
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De novo purine synthesis in cultured human fibroblasts.
Topics: Adenine; Adenosine Monophosphate; Fibroblasts; Formates; Glycine; Humans; Hypoxanthine Phosphoribosyltransferase; Phosphoribosyl Pyrophosphate; Purines; Ribonucleotides | 1979 |
Effect of triiodothyronine on the biosynthesis of adenine nucleotides and proteins in the rat heart.
Topics: Adenine; Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cardiomegaly; Female; Kinetics; Muscle Proteins; Myocardium; Organ Size; Phosphoribosyl Pyrophosphate; Propranolol; Rats; Triiodothyronine | 1977 |
Pentose shunt, phosphoribosylpyrophosphate generation and purine-phosphoribosyltransferases in erythrocytes of patients with polycythemia vera.
Topics: Adenine; Adenine Phosphoribosyltransferase; Aging; Erythrocytes; Hot Temperature; Humans; Hypoxanthine Phosphoribosyltransferase; Male; Nucleotides; Pentosephosphates; Pentoses; Pentosyltransferases; Phosphoribosyl Pyrophosphate; Polycythemia Vera; Ribose-Phosphate Pyrophosphokinase | 1975 |
Studies on the regulation of the biosynthesis of myocardial adenine nucleotides.
Topics: Adenine; Adenine Nucleotides; Aminophylline; Animals; Bucladesine; Cyclic AMP; Fatty Alcohols; Female; Gallopamil; Isoproterenol; Myocardium; Pentosephosphates; Phosphoribosyl Pyrophosphate; Propranolol; Rats | 1977 |
Regulation of de novo purine synthesis in chick liver slices. Role of phosphoribosylpyrophosphate availability and of salvage purine nucleotide synthesis.
Topics: Adenine; Adenine Phosphoribosyltransferase; Animals; Chickens; Female; Formates; Hypoxanthine Phosphoribosyltransferase; In Vitro Techniques; Kinetics; Liver; Male; Pentosephosphates; Phosphates; Phosphoribosyl Pyrophosphate; Purine Nucleotides; Purines; Rats; Ribose-Phosphate Pyrophosphokinase | 1978 |
[Possible role of high molecular weight polyphosphates in ATP synthesis from exogenous adenine by the culture of Corynebacterium sp., strain VSTI-301].
Topics: Adenine; Adenosine Triphosphate; Corynebacterium; Diphosphates; Kinetics; Phosphates; Phosphoribosyl Pyrophosphate; Phosphoric Monoester Hydrolases; Pyrophosphatases | 1979 |
Analysis of adenosine-mediated pyrimidine starvation using cultured wild-type and mutant mouse T-lymphoma cells.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Azepines; Cell Line; Cells, Cultured; Deoxyribonucleosides; Hypoxanthine Phosphoribosyltransferase; Lymphoma, Non-Hodgkin; Mice; Mutation; Phosphoribosyl Pyrophosphate; Pyrimidines; T-Lymphocytes | 1978 |
A patient with purine nucleoside phosphorylase deficiency: enzymological and metabolic aspects.
Topics: Adenine; Adenosine; Child; Erythrocytes; Female; Humans; Hypoxanthines; Inosine; Pentosyltransferases; Phosphoribosyl Pyrophosphate; Purine-Nucleoside Phosphorylase; Purines; Time Factors | 1977 |
Incorporation of purine bases by intact red blood cells.
Topics: Adenine; Biological Transport; Erythrocytes; Guanine; Humans; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Kinetics; Phosphoribosyl Pyrophosphate; Purine-Nucleoside Phosphorylase | 1977 |
Regulation of purine de novo synthesis in cultured human fibroblasts: the role of P-ribose-PP.
Topics: Adenine; Blood; Cells, Cultured; Formates; Glycine; Humans; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Pentosephosphates; Phosphoribosyl Pyrophosphate; Purines | 1979 |
Effects of ethidium and isometamidium on adenosine triphosphate catabolism and purine nucleotide synthesis in Ehrlich ascites tumor cells in vitro.
Topics: Adenine; Adenosine Triphosphate; Animals; Benzamidines; Carcinoma, Ehrlich Tumor; DNA, Neoplasm; Ethidium; Glucose; Glycine; Glycolysis; Hypoxanthines; Neoplasm Proteins; Nucleic Acid Precursors; Oxidative Phosphorylation; Oxygen Consumption; Phenanthridines; Phosphoribosyl Pyrophosphate; Purine Nucleotides; RNA, Neoplasm | 1977 |
Experimental modulation of PRPP availability for ribonucleotide synthesis from hypoxanthine in human skin fibroblast cultures.
Topics: Adenine; Adenosine; Cell Line; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Kinetics; Methylene Blue; Orotic Acid; Pentosephosphates; Phosphoribosyl Pyrophosphate; Ribonucleotides | 1978 |
Cytotoxic and metabolic effects of adenosine and adenine on human lymphoblasts.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Azepines; Cell Division; Humans; Lymphocytes; Phosphoribosyl Pyrophosphate; Pyrimidine Nucleotides; Ribonucleosides; Uridine | 1978 |
Purine reutilization and synthesis de novo in APRT deficient long-term lymphocyte lines.
Topics: Adenine; Adenine Phosphoribosyltransferase; Cell Line; Formates; Humans; Hypoxanthines; Kinetics; Lymphocytes; Pentosyltransferases; Phosphoribosyl Pyrophosphate; Purines | 1978 |
Adenine nucleotide synthesis and growth rate of the adenyl succinate lyase mutant of Bacillus anthracis.
Topics: Adenine; Adenine Nucleotides; Adenosine Monophosphate; Bacillus anthracis; Carbon Radioisotopes; Cell-Free System; Chromatography, Thin Layer; Hypoxanthines; Inosine; Ligases; Lyases; Mutation; Phosphoribosyl Pyrophosphate; Sonication; Succinates | 1975 |
Coordinate regulation of the proximal and distal steps of the pathway of purine synthesis de nono in WI-L2 human lymphoblasts.
Topics: Adenine; Adenine Nucleotides; Adenosine Kinase; Azaserine; Cell Line; Feedback; Formates; Guanine; Hypoxanthines; Inosine Nucleotides; Kinetics; Ligases; Lymphocytes; Phosphoribosyl Pyrophosphate; Purine Nucleotides; Purines; Thioinosine | 1977 |
Purine toxicity in human lymphoblasts.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Cell Division; Cell Line; Drug Synergism; Glucose; Hypoxanthines; Lymphocytes; Mutation; Phosphoribosyl Pyrophosphate; Purines; Ribonucleotides; Uridine | 1977 |
The control of cell proliferation by preformed purines: a genetic study. II. Pleiotropic manifestations and mechanism of a control exerted by adenylic purines on PRPP synthesis.
Topics: Adenine; Adenosine; Adenosine Kinase; Anti-Bacterial Agents; Azepines; Cell Line; Hypoxanthine Phosphoribosyltransferase; Mutation; Pentosephosphates; Phosphoribosyl Pyrophosphate; Ribonucleosides | 1977 |
Purine metabolism in thioguanine-resistant glioma cells.
Topics: Adenine; Amidophosphoribosyltransferase; Cell Line; Guanine; Hypoxanthine Phosphoribosyltransferase; Neuroglia; Phosphoribosyl Pyrophosphate; Purines | 1976 |
The effects of added purines on urate and purine synthesis de novo by isolated chick liver, kidney and lymphoid cells.
Topics: Adenine; Adenosine Monophosphate; Animals; Chickens; Formates; Glycine; Guanine; Guanine Nucleotides; In Vitro Techniques; Inosine; Inosine Monophosphate; Kidney; Liver; Lymphoid Tissue; Phosphoribosyl Pyrophosphate; Purines; Stimulation, Chemical; Uric Acid | 1976 |
Effects of nucleoside analogs on purine nucleotide metabolism.
Topics: Adenine; Animals; Anti-Bacterial Agents; Carcinoma, Ehrlich Tumor; Guanine; Hypoxanthines; IMP Dehydrogenase; Mice; Nucleosides; Phosphoribosyl Pyrophosphate; Purine Nucleotides; Ribonucleotides; Structure-Activity Relationship | 1975 |
Contrast in adenine uptake by chicken and rabbit erythrocytes in vitro.
Topics: Adenine; Adenine Nucleotides; Adenine Phosphoribosyltransferase; Animals; Blood Proteins; Cell Membrane Permeability; Chickens; Chromatography, Thin Layer; Erythrocytes; Guanine; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Phosphoribosyl Pyrophosphate; Rabbits; Temperature | 1992 |
Metabolism and salvage of adenine and hypoxanthine by myocytes isolated from mature rat heart.
Topics: Adenine; Adenine Nucleotides; Adenosine Triphosphate; Animals; Enzymes; Guanosine Monophosphate; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine Monophosphate; Myocardium; Phosphoribosyl Pyrophosphate; Rats; Ribose | 1985 |
Purine nucleotide metabolism in resident and activated rat macrophages in vitro.
Topics: Adenine; Adenosine; Animals; Cells, Cultured; Guanine; Guanosine; Hypoxanthine; Hypoxanthines; Inosine; Macrophage Activation; Macrophages; Pentosephosphates; Phosphoribosyl Pyrophosphate; Purine Nucleotides; Rats; Thioglycolates | 1985 |
Studies on the mechanism of immunosuppression with adenine.
Topics: Adenine; Adenosine; Animals; Chromatography, High Pressure Liquid; Erythrocytes; Female; Hemolytic Plaque Technique; Hypoxanthine Phosphoribosyltransferase; Immunosuppressive Agents; Kidney; Mice; Mice, Inbred C57BL; Phosphoribosyl Pyrophosphate; Sheep; Spleen | 1985 |
Usefulness of intact erythrocyte studies in the diagnosis of inherited purine and pyrimidine defects.
Topics: Adenine; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Deoxyadenosines; Erythrocytes; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Orotic Acid; Phosphoribosyl Pyrophosphate; Purine-Pyrimidine Metabolism, Inborn Errors; Radioisotope Dilution Technique | 1986 |
Effects of uridine diphosphoglucose (UDPG) infusion on 5-phosphoribosyl pyrophosphate (PRPP) levels of mouse tissues.
Topics: Adenine; Animals; Cell Membrane Permeability; Glucose-6-Phosphate; Glucosephosphates; In Vitro Techniques; Liver; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Pentosephosphates; Phosphoribosyl Pyrophosphate; Ribose-Phosphate Pyrophosphokinase; Spleen; Uridine Diphosphate Glucose; Uridine Diphosphate Sugars | 1987 |
Partial and complete adenine phosphoribosyltransferase deficiency associated with 2,8-dihydroxyadenine urolithiasis: kinetic and immunochemical properties of APRT.
Topics: Adenine; Adenine Phosphoribosyltransferase; Child, Preschool; Erythrocytes; Female; Heterozygote; Hot Temperature; Humans; Kinetics; Middle Aged; Pedigree; Pentosyltransferases; Phosphoribosyl Pyrophosphate; Urinary Calculi | 1987 |
Salvage mechanisms for regeneration of adenosine triphosphate in rat cardiac myocytes.
Topics: Adenine; Adenosine; Adenosine Kinase; Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Female; Kinetics; Myocardium; Phosphoribosyl Pyrophosphate; Rats; Rats, Inbred Strains | 1987 |
Purine nucleotide metabolism in phytohemagglutinin-induced human T lymphocytes.
Topics: Adenine; Adenine Nucleotides; DNA; Guanine; Guanine Nucleotides; Humans; Hypoxanthine; Hypoxanthines; Inosine Monophosphate; Pentosephosphates; Phosphoribosyl Pyrophosphate; Phytohemagglutinins; Purine Nucleotides; RNA; T-Lymphocytes | 1987 |
Erythrocyte adenine PRPP availability in two types of APRT deficiency using silicon oil method.
Topics: Adenine; Adenine Phosphoribosyltransferase; Diagnosis, Differential; Erythrocytes; Heterozygote; Homozygote; Humans; Hypoxanthines; Pentosephosphates; Pentosyltransferases; Phosphoribosyl Pyrophosphate; Silicon | 1989 |
Adenine uptake by isolated rat thymocytes.
Topics: Adenine; Adenine Phosphoribosyltransferase; Animals; Biological Transport; Female; In Vitro Techniques; Kinetics; Male; Methylene Blue; Phosphoribosyl Pyrophosphate; Rats; Ribose-Phosphate Pyrophosphokinase; Sulfhydryl Reagents; Thymus Gland | 1980 |
Phosphoribosylpyrophosphate bioavailability in diabetic rat renal cortex in vivo.
Topics: Adenine; Adenosine Triphosphate; Animals; Biological Availability; Diabetes Mellitus, Experimental; Infusions, Parenteral; Kidney Cortex; Male; Orotic Acid; Pentosephosphates; Phosphoribosyl Pyrophosphate; Rats; RNA; Uridine Triphosphate | 1980 |
Inosine synthesis and phosphoribosylpyrophosphate availability in rat liver cells in the presence of allopurinol.
Topics: Adenine; Allopurinol; Animals; Hypoxanthines; In Vitro Techniques; Inosine; Kinetics; Liver; Male; Pentosephosphates; Phosphates; Phosphoribosyl Pyrophosphate; Rats | 1980 |
Effects of adenosine and deoxyadenosine on PHA-stimulation of lymphocytes of man, horse and pig.
Topics: Adenine; Adenosine; Adult; Animals; Deoxyadenosines; Horses; Humans; In Vitro Techniques; Lymphocytes; Phosphoribosyl Pyrophosphate; Phytohemagglutinins; Species Specificity; Swine; Thymidine; Uridine | 1982 |
Characterization of purine nucleotide metabolism in primary rat muscle cultures.
Topics: Adenine; Animals; Cells, Cultured; Embryo, Mammalian; Formates; Guanine; Hypoxanthines; Kinetics; Muscles; Phosphates; Phosphoribosyl Pyrophosphate; Purine Nucleotides; Rats | 1982 |
[A new form of the Lesch-Nyhan syndrome. A study of hypoxanthine-guanine-phosphoribosyl-transferase in fibroblasts. The in vitro and in vivo effect of adenine on enzyme activity].
Topics: Adenine; Adenine Phosphoribosyltransferase; Adult; Erythrocytes; Fibroblasts; Humans; Hydrogen-Ion Concentration; Hypoxanthine Phosphoribosyltransferase; Infant; Kinetics; Lesch-Nyhan Syndrome; Male; Phosphoribosyl Pyrophosphate; Ribose-Phosphate Pyrophosphokinase; Temperature | 1982 |
Mitogenic enhancement of purine base phosphoribosylation in Swiss mouse 3T3 cells.
Topics: Adenine; Animals; Cells, Cultured; Embryo, Mammalian; Guanosine; Insulin; Kinetics; Mice; Mitogens; Pentosephosphates; Phosphoribosyl Pyrophosphate; Purine Nucleosides; Purines; Ribose-Phosphate Pyrophosphokinase; Tritium; Uridine | 1983 |
Effects of glycerol and fructose on purine synthesis de novo and on PP-ribose-P availability in rat liver cells.
Topics: Adenine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Formates; Fructose; Glycerol; In Vitro Techniques; Liver; Male; Pentosephosphates; Phosphoribosyl Pyrophosphate; Purines; Rats; Rats, Inbred Strains | 1982 |
The regulation of hypoxanthine guanine phosphoribosyl transferase activity through transfer of PRPP by metabolic cooperation.
Topics: Adenine; Animals; Cell Communication; Cell Line; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Mice; Pentosephosphates; Phosphoribosyl Pyrophosphate; Tubercidin | 1984 |
De novo synthesis of purine nucleotides in human blood platelets.
Topics: Adenine; Allopurinol; Azaserine; Blood Platelets; Formates; Humans; Hypoxanthines; Orotic Acid; Phosphoribosyl Pyrophosphate; Purine Nucleotides | 1980 |
Validation and steady-state analysis of a power-law model of purine metabolism in man.
Topics: Adenine; Adenine Phosphoribosyltransferase; Guanine; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Kinetics; Models, Biological; Phosphoribosyl Pyrophosphate; Purines; Sensitivity and Specificity; Uric Acid; Xanthine; Xanthines | 1997 |
A role for certain mouse Aprt sequences in resistance to toxic adenine analogs.
Topics: Adenine; Adenine Phosphoribosyltransferase; Amino Acid Sequence; Animals; Binding Sites; DNA Repair; Ethyl Methanesulfonate; Kinetics; Mice; Molecular Sequence Data; Mutagenesis; Phosphoribosyl Pyrophosphate; Sequence Alignment; Sequence Homology, Amino Acid; Structure-Activity Relationship; Ultraviolet Rays | 1997 |
Purification and characterization of adenine phosphoribosyltransferase from Saccharomyces cerevisiae.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine Monophosphate; Amino Acid Sequence; Cations; Chromatography; Dimerization; Enzyme Inhibitors; Enzyme Stability; Isoelectric Point; Kinetics; Molecular Sequence Data; Molecular Weight; Phosphoribosyl Pyrophosphate; Protein Conformation; Protein Denaturation; Saccharomyces cerevisiae; Sequence Alignment; Sequence Analysis; Temperature | 1997 |
Kelley-Seegmiller syndrome due to a unique variant of hypoxanthine-guanine phosphoribosyltransferase: reduced affinity for 5-phosphoribosyl-1-pyrophosphate manifested only at low, physiological substrate concentrations.
Topics: Acute Kidney Injury; Adenine; Cells, Cultured; Child, Preschool; Culture Media, Conditioned; DNA Mutational Analysis; Fibroblasts; Gout; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Jews; Lymphocytes; Male; Nucleic Acids; Nucleotides; Phosphoribosyl Pyrophosphate; Purines; Syndrome; Uric Acid | 2000 |
Purine and pyrimidine salvage in whole rat brain. Utilization of ATP-derived ribose-1-phosphate and 5-phosphoribosyl-1-pyrophosphate generated in experiments with dialyzed cell-free extracts.
Topics: Adenine; Adenosine Triphosphate; Animals; Brain; Cell-Free System; Cytosine; Dose-Response Relationship, Drug; Hypoxanthine; Ischemia; Models, Chemical; Pentoses; Phosphoribosyl Pyrophosphate; Purines; Pyrimidines; Rats; Reperfusion Injury; Ribosemonophosphates; Time Factors | 2002 |
Pathways for alpha-D-ribose utilization for nucleobase salvage and 5-fluorouracil activation in rat brain.
Topics: Adenine; Animals; Antimetabolites; Brain; Fluorouracil; In Vitro Techniques; Male; Phosphoribosyl Pyrophosphate; Purine Nucleotides; Pyrimidine Nucleotides; Rats; Rats, Sprague-Dawley; Ribose; Uracil | 2002 |
[INFLUENCE OF 5-PHOSPHORIBOSYL-1-PYROPHOSPHATE ON THE BIOSYNTHESIS OF PURINE BASES IN TISSUES WITH HIGH OR LOW CAPACITY FOR PURINE SYNTHESIS IN VITRO].
Topics: Adenine; Animals; Bone Marrow; Chick Embryo; Diphosphates; DNA; In Vitro Techniques; Liver; Metabolism; Pentosephosphates; Pharmacology; Phosphoribosyl Pyrophosphate; Purines; Rabbits; Rats; Research; RNA; Thymine | 1963 |
THE INHIBITION OF 5-PHOSPHORIBOSYL-1-PYROPHOSPHATE FORMATION BY CORDYCEPIN TRIPHOSPHATE IN EXTRACTS OF EHRLICH ASCITES TUMOR CELLS.
Topics: Adenine; Adenine Nucleotides; Animals; Antimetabolites; Carbon Isotopes; Carcinoma; Carcinoma, Ehrlich Tumor; Deoxyadenine Nucleotides; Diphosphates; Neoplasms, Experimental; Pharmacology; Phosphoribosyl Pyrophosphate; Phosphotransferases; Research | 1964 |
FORMATION OF RIBOMONONUCLEOTIDES FROM PURINE AND PYRIMIDINE BASES AND 5'-PHOSPHORIBOSYLPYROPHOSPHATE BY A SALMON MILT EXTRACT.
Topics: Adenine; Adenine Nucleotides; Animals; Carbon Isotopes; Chromatography; Cytosine; Cytosine Nucleotides; Diphosphates; Fishes; Guanine; Guanine Nucleotides; Metabolism; Nucleotides; Orotic Acid; Phosphoribosyl Pyrophosphate; Purines; Pyrimidines; Research; Salmon; Thymine; Tissue Extracts; Tritium; Uracil; Uracil Nucleotides; Xanthines | 1964 |
SYNTHESIS OF 5-PHOSPHORIBOSYL 1-PYROPHOSPHATE FROM GLUCOSE IN EHRLICH ASCITES TUMOR CELLS IN VITRO.
Topics: Adenine; Adenine Nucleotides; Animals; Carbohydrate Metabolism; Carcinoma; Carcinoma, Ehrlich Tumor; Dinitrophenols; Diphosphates; Glucose; Humans; In Vitro Techniques; Iodoacetates; Lactates; Methylene Blue; Pharmacology; Phosphoribosyl Pyrophosphate; Phosphotransferases; Research | 1965 |
AVAILABILITY OF 5-PHOSPHORIBOSYL 1-PYROPHOSPHATE FOR RIBONUCLEOTIDE SYNTHESIS IN EHRLICH ASCITES TUMOR CELLS IN VITRO.
Topics: Adenine; Animals; Carcinoma; Carcinoma, Ehrlich Tumor; Dinitrophenols; Diphosphates; Guanine; In Vitro Techniques; Iodoacetates; Metabolism; Methylene Blue; Nucleotides; Pharmacology; Phosphoribosyl Pyrophosphate; Research; Xanthines | 1965 |
THE EFFECT OF BETA-XYLOSYL ADENINE ON THE FORMATION OF 5-PHOSPHORIBOSYL-1-PYROPHOSPHATE BY CELL-FREE EXTRACTS OF TA3 ASCITES CELLS.
Topics: Adenine; Adenosine Triphosphate; Animals; Antimetabolites; Ascites; Carbon Isotopes; Diphosphates; Metabolism; Mice; Neoplasms; Neoplasms, Experimental; Nucleosides; Nucleotides; Phosphoribosyl Pyrophosphate; Research; Tissue Culture Techniques; Xylose | 1965 |
Isolation of a Chinese hamster cell mutant with low intracellular phosphoribosylpyrophosphate concentration.
Topics: Adenine; Adenine Phosphoribosyltransferase; Animals; Cell Line; Cricetinae; Cricetulus; Guanine; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Mutation; Phosphoribosyl Pyrophosphate; Ribose-Phosphate Pyrophosphokinase; Tritium | 1982 |
Metabolic engineering of the purine pathway for riboflavin production in Ashbya gossypii.
Topics: Adenine; Amidophosphoribosyltransferase; Base Sequence; Fungal Proteins; Gene Expression Regulation, Fungal; Genetic Engineering; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphoribosyl Pyrophosphate; Purines; Riboflavin; Saccharomycetales; Sequence Analysis, DNA | 2005 |
Structural complexes of human adenine phosphoribosyltransferase reveal novel features of the APRT catalytic mechanism.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine Monophosphate; Catalysis; Crystallography, X-Ray; Humans; Models, Molecular; Phosphoribosyl Pyrophosphate | 2008 |
Adenine phosphoribosyltransferase from Sulfolobus solfataricus is an enzyme with unusual kinetic properties and a crystal structure that suggests it evolved from a 6-oxopurine phosphoribosyltransferase.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine Diphosphate; Adenosine Monophosphate; Archaeal Proteins; Catalytic Domain; Crystallography, X-Ray; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Models, Molecular; Phosphoribosyl Pyrophosphate; Protein Conformation; Protein Multimerization; Ribosemonophosphates; Sulfolobus solfataricus | 2015 |
Copper ions inhibit pentose phosphate pathway function in Staphylococcus aureus.
Topics: Adenine; Animals; Copper; Mice; Pentose Phosphate Pathway; Phosphoribosyl Pyrophosphate; Ribose-Phosphate Pyrophosphokinase; Staphylococcus aureus | 2023 |