adenine and oxetanocin a

adenine has been researched along with oxetanocin a in 42 studies

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-19908 (19.05)18.7374
1990's19 (45.24)18.2507
2000's6 (14.29)29.6817
2010's8 (19.05)24.3611
2020's1 (2.38)2.80

Authors

AuthorsStudies
De Clercq, E1
Izuta, S; Kitagawa, M; Kojima, K; Shimada, N; Suzuki, M; Yoshida, S1
Azuma, M; Hasegawa, S; Kitagawa, M; Saijo, M; Saito, S; Sakuma, T; Suzutani, T; Yoshida, I1
Arai, S; Kaneko, C; Katagiri, N; Kurimoto, A; Nomura, M; Sato, H; Tameda, C; Toyota, A1
Hanai, Y; Maruyama, T; Sato, Y1
Honjo, M; Horii, T; Maruyama, T; Mitsuya, H; Nitta, K; Sato, Y; Shiota, H; Shirasaka, T1
Driscoll, JS; Marquez, VE; Milne, GW; Mitsuya, H; Shirasaki, T; Tseng, CK; Wysocki, RJ1
Kaneko, C; Katagiri, N; Nomura, M; Sato, H1
Kato, K; Nagai, M; Nishiyama, S; Nobukuni, T; Takita, T; Ueki, S; Watanabe, T; Yamamura, S1
Broder, S; Fine, RL; Hayashi, S; Matsukura, M; Mitsuya, H; Norbeck, DW; Plattner, JJ; Rosenbrook, W1
Chisaka, O; Matsubara, K; Nagahata, T; Tsurimoto, T; Ueda, K2
Hoshino, H; Seki, J; Shimada, N; Takahashi, K; Takeuchi, T; Takita, T1
Fujii, A; Hasegawa, S; Nishikiori, T; Saito, S; Shimada, N; Takita, T1
Nishiyama, Y; Shimada, N; Takahash, K; Yamamoto, N1
Fujii, A; Harada, T; Hasegawa, S; Shimada, N; Takita, T; Tomisawa, T1
Hoshino, H; Shimada, N; Shimizu, N; Takeuchi, T; Takita, T1
Fujii, A; Hasegawa, S; Iitaka, Y; Nakamura, H; Shimada, N; Takita, T1
Nakamura, M; Ohno, T1
Maruyama, T; Sato, Y1
Daikoku, T; Hoshino, H; Ikeda, R; Kitagawa, M; Masuda, A; Nishiyama, Y; Saito, S; Shimada, N; Tanaka, A1
Fukuhara, M; Maruyama, T1
Maruyama, T1
Schneller, SW; Seley, KL; Wu, J1
Ishizawa, M; Kawamura, F; Morino, T; Morita, M; Takagi, K; Takahashi, H; Tomita, K1
Mickle, T; Nair, V1
Ichikawa, E; Kato, K; Yamamura, S1
Abe, K; Maruyama, T; Nagata, H; Ohyashiki, JH; Ojima, T; Satoh, H; Tanaka, H; Wang, P; Yamamoto, K1
Chu, CK; Gumina, G1
Amano, R; Maruyama, T; Saneyoshi, M; Takahashi, H; Yamaguchi, T1
Chun, BK; Nair, V; Vadakkan, JJ1
Chen, X; Choo, H; Chu, CK; Schinazi, RF; Wang, J; Yadav, V1
Alibés, R; de March, P; Figueredo, M; Font, J; Rustullet, A1
Coates, GW; Hnatiuk, N; Howell, AR; Liang, Y; Morton, M; Rablen, PR; Rowley, JM; Whiting, BT1
Abe, H; Baba, M; Balzarini, J; Haraguchi, K; Ito, M; Kawahigashi, S; Kitagawa, Y; Kumamoto, H; Miyaike, T; Nakano, T; Tanaka, H; Wakabayashi, H1
Demizu, Y; Igarashi, J; Kato, Y; Konishi, R; Kurihara, M; Maruyama, T; Misawa, T; Sakakibara, N; Takata, M; Tsukamoto, I1
Bridwell-Rabb, J; Drennan, CL; Kang, G; Liu, HW; Zhong, A1
Bridwell-Rabb, J; Drennan, CL; Liu, HW; Sun, HG; Zhong, A1
Lilla, EA; Yokoyama, K1
Wang, SC1
Audette, G; Ebead, A; Hassan, MM; Lee-Ruff, E; Yaseen, A1
Chen, Q; Hu, K; Qu, RY; Yan, YC; Yang, GF; Zhang, H; Zhou, SM1

Reviews

5 review(s) available for adenine and oxetanocin a

ArticleYear
HIV inhibitors targeted at the reverse transcriptase.
    AIDS research and human retroviruses, 1992, Volume: 8, Issue:2

    Topics: Adenine; Antiviral Agents; Benzodiazepines; Deoxyribonucleotides; Drug Resistance, Microbial; HIV; HIV Reverse Transcriptase; Imidazoles; Nucleosides; Phosphates; Phosphorylation; Reverse Transcriptase Inhibitors

1992
[Inhibitory effects of human immunodeficiency virus on replication].
    Nihon rinsho. Japanese journal of clinical medicine, 1993, Volume: 51 Suppl

    Topics: Adenine; Anthracyclines; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Cell Adhesion; HIV; Reverse Transcriptase Inhibitors; Ribonuclease H; Streptonigrin; Virus Replication

1993
C-C bond forming radical SAM enzymes involved in the construction of carbon skeletons of cofactors and natural products.
    Natural product reports, 2018, 07-18, Volume: 35, Issue:7

    Topics: Adenine; Bacterial Proteins; Bacteriochlorophylls; Biological Products; Carbon; Coenzymes; Endopeptidases; Enzymes; Hydrolases; Molybdenum; S-Adenosylmethionine; Tunicamycin; Vitamin K 2

2018
Cobalamin-dependent radical S-adenosyl-l-methionine enzymes in natural product biosynthesis.
    Natural product reports, 2018, 08-15, Volume: 35, Issue:8

    Topics: Adenine; Aminobutyrates; Biological Products; Enzymes; Fosfomycin; Gentamicins; Methylation; S-Adenosylmethionine; Shewanella; Thiostrepton; Vitamin B 12

2018
A mini-review on synthesis and antiviral activity of natural product oxetanocin A derivatives.
    Bioorganic & medicinal chemistry, 2022, 10-15, Volume: 72

    Topics: Adenine; Antiviral Agents; Biological Products; Nucleosides; Sugars

2022

Other Studies

37 other study(ies) available for adenine and oxetanocin a

ArticleYear
Inhibitory effects of triphosphate derivatives of oxetanocin G and related compounds on eukaryotic and viral DNA polymerases and human immunodeficiency virus reverse transcriptase.
    Journal of biochemistry, 1992, Volume: 112, Issue:1

    Topics: Adenine; Adenosine Triphosphate; Animals; Antiviral Agents; Base Sequence; Cattle; Guanine; Guanosine Triphosphate; HIV Reverse Transcriptase; Humans; Kinetics; Male; Molecular Sequence Data; Nucleic Acid Synthesis Inhibitors; Rats; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Viral Proteins

1992
Antiviral activity of oxetanocins against varicella-zoster virus.
    Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:7

    Topics: Adenine; Antiviral Agents; Cell Survival; Cells, Cultured; Herpesvirus 3, Human; Humans; Thymidine Kinase; Virus Replication

1991
Synthesis of purine bases having a di(hydroxymethyl)cyclopentenyl group by means of high-pressure reaction and their anti-HIV activity.
    Nucleic acids symposium series, 1991, Issue:25

    Topics: Adenine; Adenosine; Antiviral Agents; Dideoxynucleosides; HIV; Molecular Structure; Prospective Studies

1991
Synthesis of methylenecyclobutyl- and cyclobutenyl adenine A, potent antiviral carbocyclic analogues of oxetanocin A.
    Nucleic acids symposium series, 1991, Issue:25

    Topics: Adenine; Adenosine; Antiviral Agents; Molecular Structure

1991
Synthesis and antiviral activities of carbocyclic oxetanocin analogues.
    Chemical & pharmaceutical bulletin, 1990, Volume: 38, Issue:10

    Topics: Adenine; Animals; Antiviral Agents; Cytopathogenic Effect, Viral; HIV; Simplexvirus; Vero Cells

1990
A ring-enlarged oxetanocin A analogue as an inhibitor of HIV infectivity.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:1

    Topics: Adenine; Antiviral Agents; Cell Line; HIV; Humans; Indicators and Reagents; Models, Molecular; Molecular Conformation; Molecular Structure; Structure-Activity Relationship; X-Ray Diffraction

1991
Highly stereoselective synthesis of carbocyclic oxetanocin and its related compounds from bicycloamides.
    Nucleic acids symposium series, 1990, Issue:22

    Topics: Adenine; Amides; Antiviral Agents; Bridged Bicyclo Compounds; Molecular Structure; Stereoisomerism

1990
Synthesis of unusual nucleosides and evaluations of their biological properties.
    Nucleic acids symposium series, 1990, Issue:22

    Topics: Adenine; Antiviral Agents; Cyclopropanes; Nucleosides; Structure-Activity Relationship

1990
Cyclobut-A and cyclobut-G, carbocyclic oxetanocin analogs that inhibit the replication of human immunodeficiency virus in T cells and monocytes and macrophages in vitro.
    Antimicrobial agents and chemotherapy, 1990, Volume: 34, Issue:2

    Topics: Adenine; Antiviral Agents; Blotting, Southern; Cell Line; Cytopathogenic Effect, Viral; Guanine; HIV-1; HIV-2; Humans; Macrophage Activation; Macrophages; Mitogens; Monocytes; Nucleosides; T-Lymphocytes; Virus Replication

1990
An in vitro system for screening anti-hepatitis B virus drugs.
    Virology, 1989, Volume: 169, Issue:1

    Topics: Acyclovir; Adenine; Antiviral Agents; Blotting, Southern; Carcinoma, Hepatocellular; Cytarabine; Dideoxyadenosine; Dideoxynucleosides; DNA Replication; DNA, Viral; Hepatitis B virus; Humans; Interferons; Liver Neoplasms; Tumor Cells, Cultured; Vidarabine; Virus Replication; Zalcitabine; Zidovudine

1989
Anti-hepatitis B virus activities of purine derivatives of oxetanocin A.
    The Journal of antibiotics, 1989, Volume: 42, Issue:4

    Topics: Adenine; Anti-Bacterial Agents; Blotting, Southern; DNA Replication; DNA, Bacterial; Hepatitis B virus; Virus Replication

1989
Inhibition of infectivity of human immunodeficiency virus by a novel nucleoside, oxetanocin, and related compounds.
    Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:5

    Topics: Adenine; Allopurinol; Anti-Bacterial Agents; Cells, Cultured; Chromatography, High Pressure Liquid; HIV; Humans; In Vitro Techniques; Mycophenolic Acid; T-Lymphocytes

1989
Derivatives of oxetanocin: oxetanocins H, X and G, and 2-aminooxetanocin A.
    The Journal of antibiotics, 1987, Volume: 40, Issue:12

    Topics: Adenine; Anti-Bacterial Agents; Biotransformation; Chemical Phenomena; Chemistry; Mass Spectrometry; Simplexvirus

1987
Selective inhibition of human cytomegalovirus replication by a novel nucleoside, oxetanocin G.
    Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:7

    Topics: Adenine; Antiviral Agents; Cell Cycle; Cytomegalovirus; DNA, Viral; Fibroblasts; Guanine; Humans; Simplexvirus; Viral Proteins; Virus Replication

1988
Oxetanocin, a novel nucleoside from bacteria.
    The Journal of antibiotics, 1986, Volume: 39, Issue:11

    Topics: Adenine; Animals; Anti-Bacterial Agents; Bacillus; Bacillus megaterium; HeLa Cells; Mice; Simplexvirus; Spectrophotometry, Infrared; Staphylococcus aureus; Vero Cells; Vesicular stomatitis Indiana virus

1986
Inhibition of infectivity of human immunodeficiency virus by oxetanocin.
    The Journal of antibiotics, 1987, Volume: 40, Issue:7

    Topics: Adenine; Antigens, Viral; Antiviral Agents; Cell Line; HIV; Humans

1987
The X-ray structure determination of oxetanocin.
    The Journal of antibiotics, 1986, Volume: 39, Issue:11

    Topics: Adenine; Chemical Phenomena; Chemistry; Molecular Conformation; X-Ray Diffraction

1986
Synthesis and antiviral activity of 3'-fluorocarbocyclic oxetanocin A.
    Chemical & pharmaceutical bulletin, 1995, Volume: 43, Issue:1

    Topics: Adenine; Animals; Antiviral Agents; Cell Line; Cytomegalovirus; Herpesvirus 1, Human; Herpesvirus 2, Human; HIV-1; Humans; Viral Plaque Assay

1995
Synthesis and antiviral activity of adenosine deaminase-resistant oxetanocin A derivatives: 2-halogeno-oxetanocin A.
    The Journal of antibiotics, 1993, Volume: 46, Issue:6

    Topics: Adenine; Adenosine Deaminase; Animals; Anti-Bacterial Agents; Antiviral Agents; HIV-1; Hydrocarbons, Halogenated; Male; Mice; Mice, Inbred ICR; Structure-Activity Relationship

1993
Synthesis and antitumor activity of phenyl carbocyclic oxetanocin and related compounds.
    Chemical & pharmaceutical bulletin, 1996, Volume: 44, Issue:7

    Topics: Adenine; Antineoplastic Agents; Humans; Tumor Cells, Cultured

1996
Synthesis of carbocyclic oxetanocin analogs bearing fluorine and their antiviral activities.
    Nucleic acids symposium series, 1995, Issue:34

    Topics: Adenine; Antiviral Agents; Cytomegalovirus; Fluorine; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; In Vitro Techniques; Methods; Molecular Structure

1995
Carbocyclic oxetanocins lacking the C-3' methylene.
    Journal of medicinal chemistry, 1997, Apr-25, Volume: 40, Issue:9

    Topics: Adenine; Adenosine; Animals; Antiviral Agents; Cells, Cultured; Giant Cells; Guanine; Herpesvirus 1, Human; Herpesvirus 3, Human; HIV-1; HIV-2; Humans; Magnetic Resonance Spectroscopy; Molecular Structure; Viruses

1997
Cloning of oxetanocin A biosynthetic and resistance genes that reside on a plasmid of Bacillus megaterium strain NK84-0128.
    Bioscience, biotechnology, and biochemistry, 1999, Volume: 63, Issue:3

    Topics: Adenine; Anti-Bacterial Agents; Antiviral Agents; Bacillus megaterium; Cloning, Molecular; Drug Resistance, Microbial; Mutation; Plasmids

1999
Correlation of anti-HIV activity with structure: use of electrostatic potential and conformational analysis.
    Bioorganic & medicinal chemistry letters, 1999, Jul-19, Volume: 9, Issue:14

    Topics: Adenine; Anti-HIV Agents; Computer Simulation; Deoxyribonucleotides; Dideoxynucleosides; Hydrogen Bonding; Isomerism; Models, Chemical; Models, Molecular; Static Electricity; Structure-Activity Relationship; Zidovudine

1999
Synthesis and biological activity of unusual nucleosides having 3,4-bis(hydroxymethyl) thietane ring as a sugar moiety.
    Nucleic acids symposium series, 1999, Issue:42

    Topics: Adenine; Antiviral Agents; Indicators and Reagents; Molecular Structure

1999
(3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide) assays showed a lack of toxicity of ganciclovir (GCV), C.OXTs, and their derivatives, to TaY(OK) cells at 1 microM. Therefore we compared the antiviral potencies of these drugs at 1 microM by
    Microbiology and immunology, 2001, Volume: 45, Issue:6

    Topics: Adenine; Antiviral Agents; Dose-Response Relationship, Drug; Herpesvirus 6, Human; Humans; Tumor Cells, Cultured; Virus Replication

2001
Synthesis of L-oxetanocin.
    Organic letters, 2002, Apr-04, Volume: 4, Issue:7

    Topics: Adenine; Anti-Bacterial Agents; Bacillus megaterium; HIV-1; Indicators and Reagents; Molecular Conformation

2002
Inhibition of vertebrate telomerases by the triphosphate derivatives of carbocyclic oxetanocin analogs.
    Nucleic acids research. Supplement (2001), 2003, Issue:3

    Topics: Adenine; Animals; HeLa Cells; Humans; Salmon; Telomerase

2003
Ring-expanded analogues of natural oxetanocin: (+) and (-) hydroxymethyl isodideoxyadenosine.
    Nucleosides, nucleotides & nucleic acids, 2005, Volume: 24, Issue:5-7

    Topics: Adenine; Adenosine; Adenosine Deaminase; Anti-HIV Agents; Antiviral Agents; Glucosamine; Glucose; Magnetic Resonance Spectroscopy; Models, Chemical; Purine Nucleosides; Purine-Nucleoside Phosphorylase; Stereoisomerism; Ultraviolet Rays; X-Rays

2005
Synthesis and anti-HIV activity of D- and L-thietanose nucleosides.
    Journal of medicinal chemistry, 2006, Mar-09, Volume: 49, Issue:5

    Topics: Adenine; Anti-HIV Agents; Binding Sites; Catalysis; Cell Line; Deoxycytidine Kinase; HIV Reverse Transcriptase; HIV-1; Humans; Models, Molecular; Molecular Conformation; Phosphorylation; Pyrimidine Nucleosides; Stereoisomerism; Structure-Activity Relationship; Sulfides; Xylose

2006
Stereoselective route to oxetanocin carbocyclic analogues based on a [2 + 2] photocycloaddition to a chiral 2(5H)-furanone.
    Organic letters, 2007, Jul-19, Volume: 9, Issue:15

    Topics: Adenine; Furans; Photochemistry; Stereoisomerism

2007
Access to oxetane-containing psico-nucleosides from 2-methyleneoxetanes: a role for neighboring group participation?
    The Journal of organic chemistry, 2011, Dec-16, Volume: 76, Issue:24

    Topics: Adenine; Antiviral Agents; Butylene Glycols; Epoxy Compounds; Ethers, Cyclic; Fluorine; Furans; Humans; Lactones; Magnetic Resonance Spectroscopy; Molecular Structure; Nucleosides; Stereoisomerism

2011
Tuning efficiency of the 4-exo-trig cyclization by the electronic effect: ring closure of 3,3-difluoro-4-pentenyl carbon radicals and synthesis of a gem-difluorocyclobutane nucleoside.
    Chemical communications (Cambridge, England), 2012, Nov-18, Volume: 48, Issue:89

    Topics: Adenine; Alkenes; Butanes; Carbon; Cyclization; Fluorine; Free Radicals; Molecular Structure; Nucleosides

2012
Synthesis and Evaluation of Novel Carbocyclic Oxetanocin A (COA-Cl) Derivatives as Potential Tube Formation Agents.
    Chemical & pharmaceutical bulletin, 2015, Volume: 63, Issue:9

    Topics: Adenine; Angiogenesis Inhibitors; Cell Culture Techniques; Cell Proliferation; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Fibroblasts; Humans; Molecular Structure; Structure-Activity Relationship

2015
An HD domain phosphohydrolase active site tailored for oxetanocin-A biosynthesis.
    Proceedings of the National Academy of Sciences of the United States of America, 2016, 11-29, Volume: 113, Issue:48

    Topics: Adenine; Aspartic Acid; Bacillus megaterium; Binding Sites; Catalysis; Catalytic Domain; Crystallography, X-Ray; Histidine; Kinetics; Phosphoric Monoester Hydrolases; Protein Conformation; Signal Transduction; Substrate Specificity

2016
A B
    Nature, 2017, 04-20, Volume: 544, Issue:7650

    Topics: Adenine; Adenosine Monophosphate; Bacillus megaterium; Bacterial Proteins; Biocatalysis; Coenzymes; Crystallography, X-Ray; Deoxyadenine Nucleotides; Genes, Bacterial; Models, Molecular; Multigene Family; Protein Conformation; S-Adenosylmethionine; Vitamin B 12

2017
Synthesis of cyclobutane nucleoside analogues 3: Preparation of carbocyclic derivatives of oxetanocin.
    Nucleosides, nucleotides & nucleic acids, 2018, Volume: 37, Issue:9

    Topics: Adenine; Cyclobutanes; Nucleosides; Purines; Stereoisomerism

2018