Compounds > adenine

adenine and osimertinib

adenine has been researched along with osimertinib in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's4 (100.00)2.80

Authors

AuthorsStudies
Cui, Y; Feng, D; Liu, X; Zheng, M; Zhong, D1
Campos, S; Evans, JP; Fournier, JCL; Patel, VK; Thomas, DA; Tomkinson, NCO; White, GV; Zappacosta, F1
Feng, M; Han, R; He, Y; Hu, C; Li, J; Li, L; Li, Z; Lin, C; Liu, Z; Lu, C; Tang, X; Wang, Y; Zhang, K; Zhang, Y; Zhuang, Y1
Wang, Z; Yong Chan, EC1

Other Studies

4 other study(ies) available for adenine and osimertinib

ArticleYear
Characterization of covalent binding of tyrosine kinase inhibitors to plasma proteins.
    Drug metabolism and pharmacokinetics, 2020, Volume: 35, Issue:5

    Topics: Acrylamides; Adenine; Aminoquinolines; Aniline Compounds; Animals; Binding Sites; Dogs; Haplorhini; Humans; Indoles; Lysine; Mice; Molecular Docking Simulation; Molecular Structure; Piperidines; Protein Kinase Inhibitors; Pyridines; Pyrimidines; Quinolines; Rabbits; Rats; Serum Albumin, Human

2020
Acetylation of the Catalytic Lysine Inhibits Kinase Activity in PI3Kδ.
    ACS chemical biology, 2021, 09-17, Volume: 16, Issue:9

    Topics: Acetylation; Acrylamides; Adenine; Afatinib; Amino Acid Sequence; Aniline Compounds; Catalysis; Catalytic Domain; Class I Phosphatidylinositol 3-Kinases; Humans; Lysine; Mass Spectrometry; Molecular Docking Simulation; Phosphoinositide-3 Kinase Inhibitors; Piperidines; Protein Binding; Protein Conformation; Substrate Specificity

2021
Ibrutinib reverses IL-6-induced osimertinib resistance through inhibition of Laminin α5/FAK signaling.
    Communications biology, 2022, 02-23, Volume: 5, Issue:1

    Topics: Acrylamides; Adenine; Aniline Compounds; Carcinoma, Non-Small-Cell Lung; Drug Resistance, Neoplasm; ErbB Receptors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Interleukin-6; Laminin; Lung Neoplasms; Mutation; Piperidines

2022
Inhibition of Cytochrome P450 2J2-Mediated Metabolism of Rivaroxaban and Arachidonic Acid by Ibrutinib and Osimertinib.
    Drug metabolism and disposition: the biological fate of chemicals, 2022, Volume: 50, Issue:10

    Topics: Acrylamides; Adenine; Aniline Compounds; Arachidonic Acid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Indoles; Piperidines; Pyrimidines; Rivaroxaban

2022