adenine and orotic acid

adenine has been researched along with orotic acid in 136 studies

Research

Studies (136)

TimeframeStudies, this research(%)All Research%
pre-1990124 (91.18)18.7374
1990's10 (7.35)18.2507
2000's1 (0.74)29.6817
2010's1 (0.74)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Dragún, M; Rada, B1
Bhargava, PM; Bornecque, CA; Szafarz, D; Zajdela, F1
Christopherson, RI; Finch, LR1
Milner, JA1
Cox, RP; Holland, MJ; Klein, NC1
Cameron, JS; McBurney, A; Simmonds, HA; Van Acker, KJ1
Geshanova, E; Zhivkov, V1
Bakanova, NV; Leutskií, KM1
Henderson, GI; Schenker, S1
Kumar, A; Malt, RA; Ouellette, AJ1
Balavoine, S; Feldmann, G; Lardeux, B; Rogier, E1
Nelson, J; Qureshi, IA; Vasudevan, S1
Kato, S; Kitada, T; Morichi, T; Suzuki, I; Yano, N1
Fairbanks, LD; Simmonds, HA; Webster, DR1
Lee, GS; Ritzel, RG; Savage, EA; von Borstel, RC1
Ord, MG; Stocken, LA2
Carr, J; Hollingsworth, JW1
Hosono, R; Kuno, S1
Kummer, D1
Fox, IH; Kelley, WN3
Sidransky, H; Verney, E; Wagle, DS1
Sprecher-Goldberger, S1
Doremus, HM; Jaffe, JJ1
Fox, IH; Greene, ML; Kelley, WN; Levy, RI; Rosenbloom, FM; Seegmiller, JE1
Chudinova, IA; Davidova, SY; Gorozhanskaya, EG; Krechetova, GD; Shapot, VS; Vornovitskaya, GI; Zhubanova, AA1
Beardmore, TD; Kelley, WN; Meade, JC1
Bagnara, AS; Finch, LR1
Hüttermann, J; Müller, A1
Bagnara, AS; Brox, LW; Henderson, JF1
Feigelson, M; Feigelson, P1
Christow, CP1
Brykina, EV; Chernovskaya, TV; Lerman, MI; Podobed, OV1
Bociat, T; Capusan, I; Lazar, V; Moisi, IG; Opincaru, E1
Farber, JL; Farmar, R; Serroni, A; Shinozuka, H1
Jacobs, RL; Koontz, LC; Miller, LH1
Riede, UN; Rohr, HP1
Becker, MA; Seegmiller, JE1
Exinger, F; Korch, CT; Lacroute, F1
Gleeson, RA; Hill, RN; Smith, SJ; Vesell, ES1
Howell, BA; Kizer, DE1
Booden, T; Hull, RW1
Dewey, VC; Kidder, GW1
Coleman, RD; Hardy, D; Hurlbert, RB; Stankovich, M1
Elaev, NR1
Farber, JL; Konishi, Y; Shinozuka, H1
Camakaris, J; Cotton, RG; Danks, DM1
Clouse, JA; Kizer, DE2
Barr, CF; Polet, H1
Mandel, HG; Szapáry, D; Triester, SR1
Cerna, I; Fay, PJ; Klubes, P1
Chlumský, J; Hyncík, V1
Trager, W1
Gelderman, AH; Keister, DB; Perrotto, J1
Koenig, E1
Buchowicz, J; Grzelczak, Z1
Chou, JY; Dickman, SR1
Heath, RL1
Kaneko, T; LePage, GA1
Kelley, WN; Wyngaarden, JB1
Marchetti, M; Moruzzi, G1
Fox, RM; O'Sullivan, WJ; Wood, MH1
Hori, M; Kunimoto, T; Sawa, T; Umezawa, H; Wakashiro, T1
Dianzani, MU; Torrielli, MV; Ugazio, G1
Matolcsy, G; Pozsár, BI1
Hempstead, KW; Kopp, LE; Miech, RP; Santos, JN1
Harris, EJ; Manchester, KL1
Farber, E; Stewart, GA1
Drews, J1
Klatskin, G; Scheig, R; Simon, JB2
Held, I; Koenig, H; Wells, W1
Adams, WR; Handschumacher, RE; Rajalakshmi, S1
Fausto, N1
Gillette, JR; Holtzman, JL1
Caldarera, CM; Marchetti, M; Puddu, P1
Busch, H; Muramatsu, M1
Spaeth, AE; Windmueller, HG1
Farber, E; Shull, KH; Villa-Trevino, S1
Groth, DP; Jiang, N1
Adams, DH1
Sartorelli, AC; Tsunamura, S1
Georg, D; Mähr, G; Rommel, K; Török, M1
Arion, VJ; Georgiev, GP; Mantieva, VL1
Barry, JM; Leader, DP1
Cachin, M; Charbonnier, A; Lafille, C; Rousselot, P1
Manchester, KL1
Cain, DF1
Dennis, J; Kisilevsky, R1
Cortes, P; Levin, NW; Schoenberger, AM; Venkatachalam, KK; Verghese, CP1
Bernstein, J; Cortes, P; Dumler, F; Goldman, J; Levin, NW; Sastry, KS; Venkatachalam, H; Venkatachalam, KK1
Gröbner, W; Löffler, W; Reiter, S; Zöllner, N1
Ifft, KH; Kari, FW; Ulman, EA; Visek, WJ1
Furuta, S; Hashimoto, T; Miyazawa, S1
Aoyama, Y; Ashida, K; Yoshida, A1
Bashkite, EA; Fridrikh, A; Khovĭka, LA; Vaniushin, BF1
Boer, P; Jerushalmy, Z; Patya, M; Sperling, O1
Allshire, RC; Cranston, G; Nimmo, ER1
Laconi, E; Rajalakshmi, S; Rao, PM; Sarma, DS; Sheikh, A; Yusuf, A1
Blachowski, S; Grzelkowska, K; Kasterka, M; Motyl, T1
Nelson, J; Qureshi, IA; Sarma, DS; Vasudevan, S1
Narasimhan, S; Pascale, RM; Rajalakshmi, S; Sharma, RK1
Kidouchi, K; Ohba, S; Sumi, S; Wada, Y1
Hariguchi, F; Hayashi, T; Kobayashi, N; Matsuno, T; Okada, Y; Okamoto, T1
Zimmer, HG1
Gautsch, J; Hoekstra, D; Saghbini, M1
BECKMANN, K; BRUGEL, H; MERTZ, DP1
ROGERS, S1
ALLODI, A; MURATORI, F1
KOENIG, H2
KIPPING, H1
NAYFEH, SN; SCHNEIDER, JH1
KLETHI, J; MANDEL, P; VIRMAUX, N1
WINDMUELLER, HG3
GAJDOS, A; GAJDOS-TOEROEK, M2
AOKI, A; IBUKI, F; MATSUSHITA, S1
BORKOWSKA, I; MANDEL, L; MANDEL, P; WINTZERITH, M1
AMMANN, EC; LYNCH, VH1
BENNETT, LL; SMITHERS, D; WARD, CT1
TARR, HL1
AKAMATSU, N; COHEN, PP; LINDSAY, RH1
RAJALAKSHMI, S; SARMA, DS; SARMA, PS; SRIRAMACHARI, S1
MANDEL, P; MICHAELIDIS, P1
ADAMS, HR; BUSCH, H1
GORDON, CN; SHIGEURA, HT1
LEPAGE, GA; SATO, K1
JAFFE, JJ; MOMPARLER, RL1
BHARGAVA, PM; JACOB, ST1

Reviews

5 review(s) available for adenine and orotic acid

ArticleYear
Phosphoribosylpyrophosphate in man: biochemical and clinical significance.
    Annals of internal medicine, 1971, Volume: 74, Issue:3

    Topics: Adenine; Adrenocorticotropic Hormone; Allopurinol; Animals; Glycogen; Gout; Humans; Lesch-Nyhan Syndrome; Methylene Blue; Orotic Acid; Pentosephosphates; Phosphoric Acids; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Ribose; Thiadiazoles; Thyrotropin; Transferases; Urate Oxidase; Uric Acid

1971
Notes on some peculiarities of enzymic processes in malignant tumours and tissues of the host.
    Neoplasma, 1972, Volume: 19, Issue:4

    Topics: Adenine; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Catalase; Cholesterol; DNA, Neoplasm; Humans; Isoenzymes; L-Lactate Dehydrogenase; Leukemia, Lymphoid; Leukemia, Myeloid; Leukocytes; Liver; Liver Neoplasms; Lymphocytes; Neoplasms; Neoplasms, Experimental; Orotic Acid; Pyrimidine Nucleotides; Rats; RNA, Neoplasm; Uracil

1972
[The reaction pattern of liver-peroxysomes (equal microbodies) during cell-injury (author's transl)].
    Beitrage zur Pathologie, 1974, Volume: 151, Issue:2

    Topics: Adenine; Aspirin; Chloramphenicol; Cycloheximide; Epinephrine; Folic Acid; Liver; Microbodies; Mitochondria; Mitochondria, Liver; Mitochondrial Swelling; Organoids; Orotic Acid; Penicillamine; Vitamin D Deficiency

1974
Genetic aspects of gout.
    Annual review of medicine, 1974, Volume: 25, Issue:0

    Topics: Adenine; Allopurinol; Carbon Radioisotopes; Erythrocytes; Fibroblasts; Glucosephosphate Dehydrogenase; Glutamine; Glutathione Reductase; Gout; Guanine; Humans; Hypoxanthines; Lesch-Nyhan Syndrome; Liver; Metabolic Diseases; Molecular Weight; Orotic Acid; Pentosyltransferases; Purines; Uric Acid; Xanthine Oxidase

1974
Significance of the 5-phosphoribosyl-1-pyrophosphate pool for cardiac purine and pyrimidine nucleotide synthesis: studies with ribose, adenine, inosine, and orotic acid in rats.
    Cardiovascular drugs and therapy, 1998, Volume: 12 Suppl 2

    Topics: Adenine; Animals; Inosine; Myocardium; Orotic Acid; Phosphoribosyl Pyrophosphate; Purine Nucleotides; Pyrimidine Nucleotides; Rats; Ribose

1998

Other Studies

131 other study(ies) available for adenine and orotic acid

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Inhibition of Newcastle disease virus replication by 6-azauridine. II. Combination of 6-azauridine and adenine derivatives.
    Acta virologica, 1976, Volume: 20, Issue:2

    Topics: Adenine; Azauridine; Culture Techniques; Drug Synergism; Newcastle disease virus; Orotic Acid; Purine Nucleosides; Purine Nucleotides; Pyrimidine Nucleosides; Pyrimidine Nucleotides; Virus Replication

1976
Uptake in vitro of nucleic acid precursors and nucleic acids by Zajdela ascitic hepatoma cells.
    The Journal of membrane biology, 1975, Jul-24, Volume: 22, Issue:3-4

    Topics: Adenine; Animals; Biological Transport, Active; Carcinoma, Hepatocellular; Cell Line; DNA; DNA, Bacterial; Liver; Liver Neoplasms; Orotic Acid; Rats; Ribonucleosides; RNA; RNA, Bacterial; Uracil; Uridine

1975
Response of the pyrimidine pathway of Escherichia coli K 12 to exogenous adenine and uracil.
    European journal of biochemistry, 1978, Volume: 90, Issue:2

    Topics: Adenine; Aspartate Carbamoyltransferase; Aspartic Acid; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Carbamyl Phosphate; Escherichia coli; Kinetics; Orotate Phosphoribosyltransferase; Orotic Acid; Pyrimidines; Uracil

1978
Mechanism for fatty liver induction in rats fed arginine deficient diets.
    The Journal of nutrition, 1979, Volume: 109, Issue:4

    Topics: Adenine; Animals; Arginine; Body Weight; Cholesterol; Citrates; Fatty Liver; Female; Guanine; Lipid Metabolism; Male; Orotic Acid; Phospholipids; Rats; Triglycerides; Urea

1979
Experimental modulation of PRPP availability for ribonucleotide synthesis from hypoxanthine in human skin fibroblast cultures.
    Experimental cell research, 1978, Volume: 111, Issue:2

    Topics: Adenine; Adenosine; Cell Line; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Kinetics; Methylene Blue; Orotic Acid; Pentosephosphates; Phosphoribosyl Pyrophosphate; Ribonucleotides

1978
Purine excretion in complete adenine phosphoribosyltransferase deficiency: effect of diet and allopurinol therapy.
    Advances in experimental medicine and biology, 1977, Volume: 76B

    Topics: Adenine; Adenine Phosphoribosyltransferase; Allopurinol; Child, Preschool; Diet; Humans; Male; Orotic Acid; Pentosyltransferases; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Uric Acid

1977
(14C)-precursors incorporation into adenine and uridine nucleotides of the liver of some vertebrates.
    Comparative biochemistry and physiology. B, Comparative biochemistry, 1975, Jan-15, Volume: 50, Issue:1

    Topics: Adenine; Adenosine Monophosphate; Animals; Carbon Radioisotopes; Chickens; Columbidae; Glycine; Guinea Pigs; Liver; Male; Orotic Acid; Phosphates; Phosphorus Radioisotopes; Rats; Species Specificity; Uracil Nucleotides

1975
[The effect of orotic acid and vitamin A on 2C-14-orotic acid incorporation into the acid-soluble fraction and nucleic acids of white rat tissues].
    Nauchnye doklady vysshei shkoly. Biologicheskie nauki, 1975, Issue:2

    Topics: Adenine; Animals; Brain; Brain Chemistry; Carbon Radioisotopes; DNA; Guanine; Kidney; Liver; Male; Orotic Acid; Rats; RNA; Spleen; Testis; Uracil; Vitamin A

1975
Reversible impairment of cerebral DNA synthesis in thiamine deficiency.
    The Journal of laboratory and clinical medicine, 1975, Volume: 86, Issue:1

    Topics: Adenine; Animals; Brain; Brain Diseases; Carbon Radioisotopes; DNA; Female; Hypothermia; Organ Size; Orotic Acid; Proteins; Rats; RNA; Thiamine; Thiamine Deficiency; Thymidine; Tritium

1975
Physical aspects and cytoplasmic distribution of messenger RNA in mouse kidney.
    Biochimica et biophysica acta, 1976, Apr-02, Volume: 425, Issue:4

    Topics: Adenine; Animals; Centrifugation, Density Gradient; Cytoplasm; Kidney; Male; Mice; Molecular Weight; Orotic Acid; Poly A; Polyribosomes; Rats; RNA, Messenger

1976
Responsiveness of RNA degradation to amino acids in cultured rat hepatocytes: comparison with isolated rat hepatocytes.
    Journal of cellular physiology, 1992, Volume: 150, Issue:1

    Topics: Adenine; Amino Acids; Animals; Cell Count; Cells, Cultured; Culture Media; Kinetics; Liver; Male; Microscopy, Electron; Orotic Acid; Radioactivity; Rats; RNA

1992
[Mechanism of the effect of serine and threonine on ammoniagenesis and biosynthesis of orotate in the mouse].
    Clinical and investigative medicine. Medecine clinique et experimentale, 1992, Volume: 15, Issue:2

    Topics: Adenine; Ammonia; Animals; Aspartic Acid; Cycloheximide; Male; Mice; Mice, Inbred ICR; Orotic Acid; Phosphonoacetic Acid; Serine; Threonine

1992
Growth of Lactobacillus bulgaricus in milk. 2. Characteristics of purine nucleotides, pyrimidine nucleotides, and nucleic acid synthesis.
    Journal of dairy science, 1986, Volume: 69, Issue:4

    Topics: Adenine; Adenosine Monophosphate; Animals; Cattle; DNA, Bacterial; Guanine; Guanosine Monophosphate; In Vitro Techniques; Lactobacillus; Milk; Orotic Acid; Purine Nucleotides; RNA, Bacterial

1986
Usefulness of intact erythrocyte studies in the diagnosis of inherited purine and pyrimidine defects.
    Advances in experimental medicine and biology, 1986, Volume: 195 Pt A

    Topics: Adenine; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Deoxyadenosines; Erythrocytes; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Orotic Acid; Phosphoribosyl Pyrophosphate; Purine-Pyrimidine Metabolism, Inborn Errors; Radioisotope Dilution Technique

1986
The base-alteration spectrum of spontaneous and ultraviolet radiation-induced forward mutations in the URA3 locus of Saccharomyces cerevisiae.
    Molecular & general genetics : MGG, 1988, Volume: 214, Issue:3

    Topics: Adenine; Base Sequence; Cyclobutanes; DNA Mutational Analysis; DNA, Fungal; Genes, Fungal; Genetic Vectors; Orotic Acid; Plasmids; Pyrimidine Dimers; Saccharomyces cerevisiae; Ultraviolet Rays

1988
Uptake of amino acids and nucleic acid precursors by regenerating rat liver.
    The Biochemical journal, 1972, Volume: 129, Issue:1

    Topics: Adenine; Adrenalectomy; Amino Acids; Animals; Dactinomycin; Hepatectomy; Liver; Liver Regeneration; Lysine; Male; Ornithine; Orotic Acid; Phenylalanine; Rats; RNA; Thymidine; Tritium; Tyrosine; Uridine; Valine

1972
3H-uridine incorporation as a T lymphocyte indicator in the rat.
    Cellular immunology, 1973, Volume: 8, Issue:2

    Topics: Adenine; Adenosine; Animals; Ascitic Fluid; Autoradiography; Cycloheximide; Cytidine; Dactinomycin; Female; Lymphocyte Depletion; Lymphopenia; Male; Orotic Acid; Phosphorus Isotopes; Polyethylenes; Puromycin; Rats; Rats, Inbred Strains; T-Lymphocytes; Thoracic Duct; Tritium; Uridine

1973
Mechanism of inhibition of bacterial growth by adenine.
    Journal of biochemistry, 1974, Volume: 75, Issue:2

    Topics: Adenine; Adenosine; Adenosine Triphosphate; Bacterial Proteins; Carbon Radioisotopes; Culture Media; Depression, Chemical; DNA, Bacterial; Edetic Acid; Escherichia coli; Guanosine; Inosine; Orotic Acid; Oxygen Consumption; Phosphorus Radioisotopes; Purine Nucleotides; Pyrimidine Nucleotides; RNA, Bacterial; Uridine

1974
[Effects of cytostatics and x-rays on nucleic acid metabolism of solid, malignant tumors in vitro].
    Zeitschrift fur Krebsforschung, 1970, Volume: 74, Issue:1

    Topics: Adenine; Animals; Antineoplastic Agents; Carbon Isotopes; Dactinomycin; Depression, Chemical; DNA, Neoplasm; Estriol; Fluorouracil; Formates; Glycine; Hypoxanthines; In Vitro Techniques; Leucine; Mercaptopurine; Methotrexate; Methylprednisolone; Neoplasm Proteins; Neoplasms, Experimental; Nucleosides; Orotic Acid; Radiation Effects; RNA, Neoplasm; Testosterone; Thymidine; Triaziquone; Uracil; Uridine

1970
Pharmacological alterations of intracellular phosphoribosylpyrophosphate (PP-ribose-P) in human tissues.
    Advances in experimental medicine and biology, 1973, Volume: 41

    Topics: Adenine; Allopurinol; Deoxy Sugars; Erythrocytes; Fibroblasts; Glucose; Guanine Nucleotides; Humans; Inosine Nucleotides; Methylene Blue; Niacinamide; Nicotinic Acids; Orotic Acid; Pentosephosphates; Pentosyltransferases; Purines; Skin; Time Factors

1973
Effect of dietary orotic acid on liver glycogen.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1965, Volume: 120, Issue:2

    Topics: Adenine; Animals; Epinephrine; Fatty Liver; Glucose-6-Phosphatase; Glucosidases; Glycine; In Vitro Techniques; Liver; Liver Glycogen; Orotic Acid; Phosphotransferases; Rats; Sucrose

1965
The existence of two different metabolic patterns for the synthesis of RNA viruses.
    Archiv fur die gesamte Virusforschung, 1966, Volume: 18, Issue:2

    Topics: Adenine; Animals; Antimetabolites; Chick Embryo; Culture Media; Dactinomycin; Enterovirus; Fibroblasts; Formates; Histones; Influenza A virus; Methotrexate; Nucleosides; Orotic Acid; Phenylalanine; Puromycin; Radiation Effects; RNA Viruses; RNA, Viral; Thymidine; Ultraviolet Rays; Uridine

1966
Metabolic patterns of Dirofilaria immitis microfilariae in vitro.
    The Journal of parasitology, 1970, Volume: 56, Issue:2

    Topics: Adenine; Amino Acids; Animals; Benzenesulfonates; Carbon Dioxide; Carbon Isotopes; Diethylcarbamazine; Dithiazanine; DNA; Filarioidea; Formates; Glucose; Glycine; Glycogen; In Vitro Techniques; Lipid Metabolism; Orotic Acid; Proteins; RNA; Uracil; Uridine

1970
Effects of orotic acid on purine and lipoprotein metabolism in man.
    Metabolism: clinical and experimental, 1970, Volume: 19, Issue:12

    Topics: Adenine; Administration, Oral; Carbon Isotopes; Cholesterol; Diphosphates; Erythrocytes; Glycine; Guanine; Humans; Kidney; Lipoproteins; Metabolic Clearance Rate; Nitrogen; Orotic Acid; Purines; Radioisotopes; Ribose; Transferases; Triglycerides; Uric Acid

1970
Increased activity of two enzymes of pyrimidine biosynthesis de novo in erythrocytes from patients with the Lesch-Nyhan syndrome.
    The Journal of laboratory and clinical medicine, 1973, Volume: 81, Issue:1

    Topics: Adenine; Adolescent; Allopurinol; Carbon Isotopes; Carboxy-Lyases; Child; Child, Preschool; Diphosphates; Erythrocyte Aging; Erythrocytes; Hot Temperature; Humans; Infant; Lesch-Nyhan Syndrome; Orotic Acid; Pentosyltransferases

1973
The effects of bases and nucleosides on the intracellular contents of nucleotides and 5-phosphoribosyl 1-pyrophosphate in Escherichia coli.
    European journal of biochemistry, 1974, Feb-01, Volume: 41, Issue:3

    Topics: Adenine; Adenine Nucleotides; Adenosine; Carbon Radioisotopes; Cytosine Nucleotides; Escherichia coli; Guanine; Guanine Nucleotides; Guanosine; Hypoxanthines; Inosine; Inosine Nucleotides; Kinetics; Organophosphorus Compounds; Orotic Acid; Pentosephosphates; Phosphoric Acids; Ribonucleosides; Ribonucleotides; Time Factors; Uracil; Uracil Nucleotides; Uridine

1974
Structure and formation of free radicals in irradiated single crystals of nucleic acid constituents.
    Annals of the New York Academy of Sciences, 1973, Dec-31, Volume: 222

    Topics: Adenine; Barbiturates; Bromodeoxyuridine; Crystallization; Electron Spin Resonance Spectroscopy; Free Radicals; Guanine; Idoxuridine; Molecular Conformation; Orotic Acid; Purines; Pyrimidines; Radiation Effects; Structure-Activity Relationship; Thymine; Uracil

1973
Observations of altered intracellular phosphoribosylpyrophosphate (PP-ribose-P) in human disease.
    Advances in experimental medicine and biology, 1974, Volume: 41

    Topics: Adenine; Carbon Radioisotopes; Erythrocytes; Fibroblasts; Formates; Gout; Guanine Nucleotides; Heterozygote; Homozygote; Humans; Inosine Nucleotides; Methylene Blue; Orotic Acid; Pentosephosphates; Pentosyltransferases; Phosphoric Acids; Ribonucleotides; Uric Acid

1974
Kinetics of amidophosphoribosyltransferase in intact tumor cells.
    Biochimica et biophysica acta, 1974, May-20, Volume: 350, Issue:1

    Topics: Adenine; Animals; Azo Compounds; Carbon Radioisotopes; Carcinoma, Ehrlich Tumor; Chromatography, Ion Exchange; Chromatography, Paper; Glutamine; Kinetics; Orotic Acid; Pentosephosphates; Pentosyltransferases; Phosphoric Acids; Spectrophotometry; Time Factors

1974
Relationships between hepatic enzyme induction, glutamate formation, and purine nucleotide biosynthesis in glucocorticoid action.
    The Journal of biological chemistry, 1966, Dec-25, Volume: 241, Issue:24

    Topics: Adenine; Animals; Cortisone; Enzyme Induction; Glutamates; Glycine; In Vitro Techniques; Liver; Nucleotides; Orotic Acid; Rats; RNA; Spleen; Thymus Gland; Transaminases; Tyrosine Transaminase; Uracil Nucleotides

1966
[Experiments on the influence of metabolites and antimetabolites on the model of Trichomonas vaginalis. V. Relationship between vitamin-B-complexes and Trichomonas vaginalis].
    Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Erste Abteilung Originale. Reihe A: Medizinische Mikrobiologie und Parasitologie, 1971, Volume: 218, Issue:2

    Topics: Adenine; Adenosine Monophosphate; Bacteriological Techniques; Biotin; Carnitine; Choline; Hydrogen-Ion Concentration; Inositol; Models, Biological; Orotic Acid; Pyridoxine; Riboflavin; Thiamine; Thioctic Acid; Trichomonas vaginalis; Vitamin B Complex; Xanthopterin

1971
Lack of correlation between the lifetimes of mRNA and the initial lengths of their poly A segments.
    Molecular biology reports, 1974, Volume: 1, Issue:7

    Topics: Adenine; Adenosine Monophosphate; Animals; Base Sequence; Carbon Radioisotopes; Dactinomycin; Drug Stability; Electrophoresis, Polyacrylamide Gel; Isotope Labeling; Kinetics; Liver; Mice; Molecular Weight; Orotic Acid; Pancreas; Polyribosomes; Ribonucleases; Ribonucleotides; RNA, Messenger; Time Factors

1974
[Purinor in the treatment of porphyria cutanea tarda].
    Zeitschrift fur Hautkrankheiten, 1974, Jul-01, Volume: 49, Issue:13

    Topics: Adenine; Adult; Alanine Transaminase; Aspartate Aminotransferases; Drug Combinations; Fructosephosphates; Humans; Hypoxanthines; Inositol; Magnesium; Male; Middle Aged; Orotic Acid; Porphyrias; Porphyrins; Purines; Xanthines

1974
Reversal of the ethionine-induced inhibition of rat liver ribonucleic acid polymerases in vivo by adenine.
    Laboratory investigation; a journal of technical methods and pathology, 1974, Volume: 31, Issue:5

    Topics: Adenine; Animals; Carbon Radioisotopes; Cell Nucleus; Chromatography, DEAE-Cellulose; Cycloheximide; Depression, Chemical; DNA; DNA-Directed RNA Polymerases; Enzyme Inhibitors; Ethionine; Female; Leucine; Liver; Methionine; Mycotoxins; Oligopeptides; Orotic Acid; Peptides, Cyclic; Rats; RNA; Solubility; Tritium

1974
Labeling of sporozoites of Plasmodium berghei with tritiated purines.
    The Journal of parasitology, 1974, Volume: 60, Issue:2

    Topics: Adenine; Adenosine; Animals; Anopheles; Blood; Deoxyadenosines; Deoxyribonucleosides; Guanosine; Isotope Labeling; Malaria; Mice; Orotic Acid; Plasmodium berghei; Purines; Salivary Glands; Thymidine; Tritium

1974
A regulatory interaction between pyrimidine and purine biosyntheses via ureidosuccinic acid.
    Molecular & general genetics : MGG, 1974, Volume: 133, Issue:1

    Topics: Adenine; Aspartic Acid; Carbamates; Cytosine; Drug Resistance, Microbial; Mutation; Orotic Acid; Phenotype; Purines; Pyrimidines; Saccharomyces cerevisiae; Uracil

1974
Evidence for post-transcriptional stabilization of ribosomal precursor ribonucleic acid by phenobarbital.
    Molecular pharmacology, 1972, Volume: 8, Issue:6

    Topics: Adenine; Animals; Carbon Isotopes; Cell Nucleolus; Cell Nucleus; Centrifugation, Density Gradient; Chromatography; DNA; Drug Stability; Guanine; Liver; Male; Microsomes, Liver; Orotic Acid; Phenobarbital; Rats; RNA, Ribosomal; Sucrose; Transcription, Genetic; Tritium; Uracil Nucleotides

1972
Nucleic acid precursor uptake into normal and regenerating rat liver.
    The Biochemical journal, 1972, Volume: 130, Issue:1

    Topics: Adenine; Animals; Carbon Isotopes; DNA; Inulin; Liver; Liver Regeneration; Orotic Acid; Rats; RNA; Thymidine; Tritium; Uracil Nucleotides

1972
Synchrony between DNA synthesis and thymidine incorporation into DNA in regenerating rat liver.
    Chemico-biological interactions, 1973, Volume: 6, Issue:3

    Topics: Adenine; Animals; Aspartic Acid; Carbon Isotopes; Chromatography, DEAE-Cellulose; DNA; Female; Formates; Hydrocortisone; Hydrolysis; In Vitro Techniques; Liver; Liver Regeneration; Orotic Acid; Proteins; Rats; Stress, Physiological; Thymidine; Thymidine Kinase; Time Factors; Tritium

1973
Nucleic acid precursor synthesis by Plasmodium lophurae parasitizing chicken erythrocytes.
    Experimental parasitology, 1973, Volume: 34, Issue:2

    Topics: Adenine; Animals; Autoradiography; Carbon Radioisotopes; Chickens; Culture Media; DNA; Erythrocytes; Formates; Glycine; Malaria, Avian; Male; Orotic Acid; Plasmodium; Purine Nucleotides; Pyrimidine Nucleotides; RNA; Spectrophotometry; Thymidine; Tritium; Uracil; Uridine

1973
The sites of action of allopurinol in Crithidia fasciculata.
    The Journal of protozoology, 1973, Volume: 20, Issue:5

    Topics: Adenine; Allopurinol; Animals; Carbon Radioisotopes; Cell-Free System; Chemical Phenomena; Chemistry; Chromatography, Paper; Colorimetry; Cytosine; Dose-Response Relationship, Drug; Eukaryota; Folic Acid; Guanine; Hypoxanthines; Orotic Acid; Pentosyltransferases; Pterins; Spectrophotometry; Uracil; Xanthines

1973
Mechanism of turnover of rapidly labeled RNA in rat liver nuclei.
    Advances in enzyme regulation, 1973, Volume: 11

    Topics: Adenine; Animals; Carbon Radioisotopes; Cell Nucleus; Cytoplasm; Female; In Vitro Techniques; Liver; Methods; Orotic Acid; Phosphorus Radioisotopes; Phosphotransferases; Rats; RNA; Tritium; Uracil Nucleotides; Uridine

1973
[Relation of RNA and protein synthesis in the brain to the state of the cholino- and adrenoreceptors].
    Doklady Akademii nauk SSSR, 1974, Mar-11, Volume: 216, Issue:2

    Topics: Adenine; Amphetamine; Animals; Arecoline; Benactyzine; Brain; Carbon Radioisotopes; Female; Glycine; Haloperidol; Nerve Tissue Proteins; Orotic Acid; Rats; Receptors, Drug; RNA; Tritium; Uridine

1974
The inhibition of rat liver nuclear ribonucleic acid synthesis by galactosamine and its reversal by uridine.
    Laboratory investigation; a journal of technical methods and pathology, 1974, Volume: 30, Issue:6

    Topics: Adenine; Animals; Cell Nucleus; Chromatography, Gel; Depression, Chemical; DNA; Dose-Response Relationship, Drug; Female; Galactosamine; In Vitro Techniques; Liver; Orotic Acid; Rats; RNA; Solubility; Stimulation, Chemical; Time Factors; Tritium; Uracil Nucleotides; Uridine

1974
A screening test for urinary purines and pyrimidines and related compounds using auxotrophic mutants of Escherichia coli K12.
    Biochemical medicine, 1970, Volume: 3, Issue:4

    Topics: Adenine; Alanine; Aspartic Acid; Biological Assay; Carbamates; Child; Chromatography, Paper; Cytosine; Escherichia coli; Glycosides; Humans; Imidazoles; Inosine; Mutation; Orotic Acid; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Purinones; Pyrimidines; Ribose; Thymine; Uracil; Uric Acid

1970
Effects of hepatocarcinogens on the synthesis and content of rat liver nuclear RNA.
    Cancer research, 1968, Volume: 28, Issue:3

    Topics: Adenine; Amides; Animals; Carbon Isotopes; Carcinogens; Cell Nucleus; Female; Liver; Orotic Acid; p-Dimethylaminoazobenzene; Precancerous Conditions; Rats; RNA; Sulfhydryl Compounds

1968
DNA, RNA , and protein synthesis in erythrocytic forms of Plasmodium knowlesi.
    The American journal of tropical medicine and hygiene, 1968, Volume: 17, Issue:5

    Topics: Adenine; Animals; Antimalarials; Carbon Isotopes; Culture Media; DNA; Erythrocytes; Glycine; Haplorhini; Isoleucine; Methionine; Orotic Acid; Phenylalanine; Plasmodium; Protein Biosynthesis; RNA; Sulfur Isotopes; Thymidine; Tritium; Tryptophan; Uracil; Uridine

1968
Interference of barbiturates with pyrimidine incorporation. 3. Studies on the mechanism of the amobarbital-orotate relationship.
    Biochemical pharmacology, 1970, Volume: 19, Issue:6

    Topics: Adenine; Alcohols; Amobarbital; Animals; Arsenic; Azides; Bacillus cereus; Bacillus megaterium; Bacillus subtilis; Biological Transport; Carbon Isotopes; Cell Membrane; Chlorpromazine; Chromatography, Paper; Cyanides; Dinitrophenols; Drug Synergism; Inulin; Kinetics; Mice; Nucleic Acids; Orotic Acid; Oxygen Consumption; Pentobarbital; Potassium; Potassium Isotopes; Pyrimidines; Radioisotopes; Rubidium; Species Specificity; Sucrose; Temperature; Uracil

1970
Effect of chlorpromazine on cell wall biosynthesis and incorporation of orotic acid into nucleic acids in Bacillus megaterium.
    Biochemical pharmacology, 1971, Volume: 20, Issue:2

    Topics: Adenine; Bacillus megaterium; Bacterial Proteins; Carbon Isotopes; Cell Wall; Chlorpromazine; DNA, Bacterial; Formates; Lysine; Models, Biological; Nucleic Acids; Orotic Acid; Pimelic Acids; Promazine; RNA; RNA, Bacterial; Sulfoxides; Thymidine; Time Factors; Trifluoperazine; Uridine

1971
[Problem of active therapeutic procedure in chronic liver disease].
    Casopis lekaru ceskych, 1972, Aug-04, Volume: 111, Issue:32

    Topics: Adenine; Adult; Aged; Chronic Disease; Diet Therapy; Female; Humans; Inositol; Liver Diseases; Male; Middle Aged; Orotic Acid; Xanthines

1972
Malaria parasites (Plasmodium lophurae) developing extracellularly in vitro: incorporation of labeled precursors.
    The Journal of protozoology, 1971, Volume: 18, Issue:3

    Topics: Adenine; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Birds; Carbon Isotopes; Cell Nucleus; Choline; Coenzyme A; Culture Media; Erythrocytes; Germ-Free Life; Methionine; Methods; Orotic Acid; Plasmodium; Proline; Pyruvates; Time Factors; Tissue Extracts

1971
Incorporation of precursors into Toxoplasma DNA.
    The Journal of protozoology, 1971, Volume: 18, Issue:3

    Topics: Adenine; Animals; Carbon Isotopes; Cytidine; DNA; Guanine; Hot Temperature; Mice; Mice, Inbred Strains; Nucleic Acid Denaturation; Nucleotides; Orotic Acid; Purines; Pyrimidines; Thymidine; Time Factors; Toxoplasma; Tritium

1971
Synthetic mechanisms in the axon. IV. In vitro incorporation of [3H]precursors into axonal protein and RNA.
    Journal of neurochemistry, 1967, Volume: 14, Issue:4

    Topics: Adenine; Animals; Axons; Chloramphenicol; Dactinomycin; In Vitro Techniques; Leucine; Microscopy, Phase-Contrast; Nerve Tissue Proteins; Orotic Acid; Photomicrography; Rabbits; Ribonucleases; RNA; Spinal Nerves; Tritium

1967
Pyrimidine and purine bases and nucleosides in wheat plants.
    Acta biochimica Polonica, 1967, Volume: 14, Issue:2

    Topics: Adenine; Carbon Isotopes; Chromatography; Cytosine; Nucleosides; Orotic Acid; Purines; Pyrimidines; Radioisotope Dilution Technique; Triticum; Uracil; Uridine

1967
On relationships between induction of liver cancer with azo dyes and changes in nuclear RNA metabolism during carcinogenesis.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1969, Volume: 132, Issue:3

    Topics: Adenine; Animals; Azo Compounds; Carbon Isotopes; Cell Nucleus; Diet; Female; Liver; Liver Neoplasms; Orotic Acid; Rats; RNA

1969
Effects of urecholine and atropine on canine pancreas slices. On incorporation of 14C-adenine and 14C-orotic acid into acid-soluble metabolites and RNA.
    Archives of biochemistry and biophysics, 1969, Volume: 135, Issue:1

    Topics: Adenine; Adenine Nucleotides; Adenosine Triphosphate; Animals; Atropine; Bethanechol Compounds; Carbon Isotopes; Cell Nucleus; Centrifugation, Density Gradient; Choline; Chromatography, Thin Layer; Cytoplasm; Depression, Chemical; Dogs; Hydrogen-Ion Concentration; Hypoxanthines; In Vitro Techniques; Nucleotides; Orotic Acid; Pancreas; RNA; Secretin; Spectrophotometry; Time Factors; Ultraviolet Rays

1969
Biosynthesis de novo of purines and pyrimidines in Mesocestoides (Cestoda). I.
    The Journal of parasitology, 1970, Volume: 56, Issue:1

    Topics: Adenine; Carbon Isotopes; Cestoda; Chromatography, Thin Layer; Glycine; Isoleucine; Nucleic Acids; Orotic Acid; Purines; Pyrimidines; Uracil

1970
Studies on beta-D-xylofuranosyl-6-thioguanine in mice.
    Cancer research, 1970, Volume: 30, Issue:3

    Topics: Adenine; Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cell Line; Chromatography; DNA, Neoplasm; Female; Furans; Glycine; Guanine; Immunosuppressive Agents; Male; Mice; Neoplasms, Experimental; Orotic Acid; Protein Biosynthesis; Purines; Pyrimidines; RNA, Neoplasm; Sulfur Isotopes; Thioguanine; Xylose

1970
Effect of dietary purine restriction, allupurinol, and oxipurinol on urinary excretion of ultraviolet-absorbing compounds.
    Clinical chemistry, 1970, Volume: 16, Issue:8

    Topics: Adenine; Allopurinol; Chromatography, Ion Exchange; Diet; Humans; Hypoxanthines; Orotic Acid; Purines; Pyrimidines; Spectrophotometry; Ultraviolet Rays; Uric Acid; Uridine; Xanthine Oxidase

1970
[Biochemical mechanisms of steatosis as sequelae of "nucleotide imbalance"].
    Schweizerische medizinische Wochenschrift, 1970, Oct-03, Volume: 100, Issue:40

    Topics: Acetates; Adenine; Adenine Nucleotides; Adenosine Triphosphate; Animals; Azaserine; Biotin; Carbon Isotopes; Cholesterol; Disease Models, Animal; Ethionine; Fatty Liver; Lipid Metabolism; Lipids; Nucleotides; Orotic Acid; Phospholipids; Pyrazoles; Pyrimidines; Rats; Triglycerides

1970
Studies on the coordinate activity and liability of orotidylate phosphoribosyltransferase and decarboxylase in human erythrocytes, and the effects of allopurinol administration.
    The Journal of clinical investigation, 1971, Volume: 50, Issue:5

    Topics: Adenine; Allopurinol; Carbon Isotopes; Carboxy-Lyases; Centrifugation, Density Gradient; Depression, Chemical; Erythrocytes; Humans; Hypoxanthines; Lesch-Nyhan Syndrome; Nucleosides; Orotic Acid; Transferases; Uracil Nucleotides

1971
Biosynthesis of the formycin family.
    The Journal of antibiotics, 1971, Volume: 24, Issue:4

    Topics: Adenine; Adenine Nucleotides; Anti-Bacterial Agents; Aspartic Acid; Carbon Isotopes; Formates; Glutamates; Glycine; Nocardia; Orotic Acid; Ribose; RNA, Bacterial; Serine; Uracil

1971
Behaviour of lipoperoxidation in rat liver during orotic acid treatment.
    Life sciences. Pt. 2: Biochemistry, general and molecular biology, 1971, Jan-22, Volume: 10, Issue:2

    Topics: Adenine; Aldehydes; Animals; Arachidonic Acids; Cytoplasm; In Vitro Techniques; Lipid Metabolism; Lipids; Liver; Malonates; Microsomes, Liver; Mitochondria, Liver; Orotic Acid; Oxidation-Reduction; Peroxides; Phospholipids; Rats; Spectrophotometry; Ultraviolet Rays

1971
Regulatory effect of N6-benzyladenine and pseudothymine (6-methyluracyl) on the synthesis of nucleic acids.
    Nature, 1968, Mar-02, Volume: 217, Issue:5131

    Topics: Adenine; Carbon Isotopes; Orotic Acid; Plants; Purines; Pyrimidines; RNA; Thymine; Uracil

1968
Nucleotide metabolism in rat brain.
    Journal of neurochemistry, 1968, Volume: 15, Issue:5

    Topics: Adenine; Animals; Aspartic Acid; Carbon Isotopes; Cerebral Cortex; Chromatography, Paper; DNA; Glucosyltransferases; Glycine; Guanine; Hypoxanthines; In Vitro Techniques; Nerve Tissue Proteins; Nucleosides; Nucleotides; Orotic Acid; Oxidoreductases; Phosphotransferases; Rats; RNA; Uridine; Xanthine Oxidase; Xanthines

1968
Effect of denervation on the synthesis of ribonucleic acid and deoxyribonucleic acid in rat diaphragm muscle.
    The Biochemical journal, 1968, Volume: 108, Issue:2

    Topics: Adenine; Animals; Carbon Isotopes; Diaphragm; DNA; DNA Replication; Hypertrophy; Muscle Denervation; Muscles; Orotic Acid; Rats; RNA; Thymidine; Time Factors; Tritium

1968
The rapid acceleration of hepatic nuclear ribonucleic acid breakdown by actinomycin but not by ethionine.
    The Journal of biological chemistry, 1968, Sep-10, Volume: 243, Issue:17

    Topics: Adenine; Animals; Carbon Isotopes; Dactinomycin; Ethionine; Liver; Methionine; Orotic Acid; Rats; RNA

1968
3 nuclear RNA fractions and their relationship to polysomal mRNA.
    Die Naturwissenschaften, 1968, Volume: 55, Issue:12

    Topics: Adenine; Animals; Cell Nucleus; Cytosine; Guanine; Hybridization, Genetic; Liver; Liver Extracts; Orotic Acid; Phosphorus Isotopes; Rats; Ribosomes; RNA; RNA, Messenger; Tritium; Uracil

1968
Protection by orotic acid against the renal necrosis and fatty liver of choline deficiency.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1968, Volume: 129, Issue:3

    Topics: Adenine; Animals; Choline Deficiency; Fatty Liver; Hemorrhage; Kidney; Liver; Male; Necrosis; Orotic Acid; Rats; Triglycerides

1968
Metabolic effects of azaserine in rat brain.
    Journal of neurochemistry, 1969, Volume: 16, Issue:4

    Topics: Adenine; Animals; Azaserine; Brain; Carbon Isotopes; Centrifugation; Chromatography, Ion Exchange; Chromatography, Paper; Female; Glycine; Lysine; Nerve Tissue Proteins; Nucleotides; Orotic Acid; Paraplegia; Phenylalanine; Purines; Pyrimidines; Rats; RNA; Spectrum Analysis; Tritium

1969
Isolation and characterization of low density structures from orotic acid-induced fatty livers.
    The Journal of cell biology, 1969, Volume: 41, Issue:2

    Topics: Adenine; Animals; Carbon Isotopes; Centrifugation, Density Gradient; Endoplasmic Reticulum; Fatty Liver; Female; Lipids; Liver; Microscopy, Electron; Microsomes; Nucleotides; Orotic Acid; Proteins; Rats; Ribosomes; RNA

1969
The control of RNA synthesis during liver regeneration. OMP pyrophosphorylase and decarboxylase activities in normal and regenerating liver.
    Biochimica et biophysica acta, 1969, May-20, Volume: 182, Issue:1

    Topics: Adenine; Animals; Carbon Isotopes; Carboxy-Lyases; Genetics; Hepatectomy; Liver; Liver Regeneration; Magnesium; Male; Microsomes; Nucleotides; Orotic Acid; Pentosephosphates; Rats; RNA; Time Factors; Transferases; Uracil Nucleotides

1969
Hepatic ATP and triglyceride levels in choline-deficient rats with and without dietary orotic acid supplementation.
    The Journal of nutrition, 1969, Volume: 98, Issue:2

    Topics: Adenine; Adenosine Triphosphate; Animals; Choline Deficiency; Diet; Dietary Fats; Fatty Liver; Liver; Male; Orotic Acid; Rats; Sulfates; Triglycerides

1969
Effect of dietary orotic acid and adenine sulfate on hepatic microsomal enzymes in male and female rats.
    Biochemical pharmacology, 1969, Volume: 18, Issue:8

    Topics: Adenine; Aniline Compounds; Animals; Cytochromes; Diet; Female; Formaldehyde; Liver; Male; Microsomes; Mixed Function Oxygenases; Morphinans; Orotic Acid; Oxidoreductases; Phenols; Rats; Sex Factors; Uracil Nucleotides

1969
Metabolic aspects of "orotic acid fatty liver". Nucleotide control mechanisms of lipid metabolism.
    The Biochemical journal, 1964, Volume: 92, Issue:1

    Topics: Adenine; Aminohydrolases; Animals; DNA; Fatty Liver; Lipid Metabolism; Nucleotides; Orotic Acid; Phospholipids; Rats; RNA; Transferases; Xanthine Oxidase

1964
Studies on the nuclear and nucleolar ribonucleic acid of regenerating rat liver.
    The Journal of biological chemistry, 1965, Volume: 240, Issue:10

    Topics: Adenine; Animals; Cell Nucleolus; Cell Nucleus; Chemistry Techniques, Analytical; Cytosine; Guanine; Hepatectomy; In Vitro Techniques; Liver; Liver Regeneration; Orotic Acid; Phosphates; Rats; RNA; Ultracentrifugation; Uracil

1965
Stimulation of hepatic purine biosynthesis by orotic acid.
    The Journal of biological chemistry, 1965, Volume: 240, Issue:11

    Topics: Adenine; Animals; Chromatography, Paper; Feedback; Formates; Glycine; Hippurates; In Vitro Techniques; Liver; Orotic Acid; Purines; Rats

1965
The inhibition of liver ribonucleic acid synthesis by ethionine.
    The Journal of biological chemistry, 1966, Oct-25, Volume: 241, Issue:20

    Topics: Adenine; Adenosine Triphosphate; Animals; Cell Nucleus; Ethionine; In Vitro Techniques; Liver; Methionine; Microsomes; Orotic Acid; Rats; RNA

1966
The role of deoxyribose 5-phosphate aldolase in the synthesis of deoxyribonucleotide in mammalian cells.
    Biochemical and biophysical research communications, 1966, Jan-04, Volume: 22, Issue:1

    Topics: Adenine; Aldehyde-Lyases; Animals; Aspartic Acid; Carcinoma, Ehrlich Tumor; Deoxyuridine; DNA; Glycine; In Vitro Techniques; Liver; Liver Regeneration; Mice; Nucleotides; Orotic Acid; Protein Biosynthesis; Rats; RNA; Subcellular Fractions; Threonine; Thymidine; Uridine

1966
The relationship between cellular nucleic acids in the developing rat cerebral cortex.
    The Biochemical journal, 1966, Volume: 98, Issue:2

    Topics: Adenine; Animals; Animals, Newborn; Brain Chemistry; Cell Nucleus; Cerebral Cortex; Cytosine; DNA; Guanine; In Vitro Techniques; Microsomes; Orotic Acid; Rats; Ribosomes; RNA; Subcellular Fractions; Uracil

1966
Studies on the biochemical mode of action of a cytotoxic methylhydrazine derivative, N-isopropyl-alpha-(2-methylhydrazino)-p-toluamide.
    Molecular pharmacology, 1966, Volume: 2, Issue:4

    Topics: Adenine; Amines; Animals; Antineoplastic Agents; Carbon Isotopes; DNA; Formates; Guanine; Hydrazines; Imidazoles; Leucine; Lymphoma; Male; Mice; Neoplasms, Experimental; Nucleosides; Nucleotides; Orotic Acid; Protein Biosynthesis; Purines; RNA; Thymidine; Thymidine Kinase; Tritium

1966
[Effects and side-effects of orotic acid].
    Die Medizinische Welt, 1966, May-28, Volume: 22

    Topics: Adenine; Animals; Drug Synergism; Fatty Liver; Galactosemias; Nucleotides; Orotic Acid; Purines; Rats

1966
Metabolically stable and metabolically labile DNA-like RNA.
    Biochimica et biophysica acta, 1967, Apr-18, Volume: 138, Issue:2

    Topics: Adenine; Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cell Nucleus; Cytosine; DNA; DNA, Neoplasm; Guanine; In Vitro Techniques; Liver; Mice; Orotic Acid; RNA; RNA, Neoplasm; Ultracentrifugation; Uracil

1967
Counter-current distribution of rapidly labelled RNA from rats treated with hormones.
    Nature, 1967, Sep-23, Volume: 215, Issue:5108

    Topics: Adenine; Animals; Carbon Isotopes; Countercurrent Distribution; Hydrocortisone; In Vitro Techniques; Insulin; Liver; Orotic Acid; Rats; RNA; Thyroxine; Tritium

1967
[Orotic acid and hepatic regeneration after partial hepatectomy in the rat].
    Revue internationale d'hepatologie, 1967, Volume: 17, Issue:5

    Topics: Adenine; Animals; Dietary Carbohydrates; Dietary Proteins; Hepatectomy; Lipids; Liver; Liver Regeneration; Orotic Acid; Rats; Sulfates

1967
Re-evaluation of the effect of insulin on nucleic acid synthesis in muscle.
    The Biochemical journal, 1967, Volume: 105, Issue:1

    Topics: Adenine; Animals; Carbon Isotopes; Diaphragm; Insulin; Muscles; Orotic Acid; Rats; RNA; Uracil

1967
Biosynthesis of RNA in slices of guinea pig cerebral cortex.
    Journal of neurochemistry, 1967, Volume: 14, Issue:12

    Topics: Adenine; Animals; Carbon Isotopes; Cerebral Cortex; Chromatography, Thin Layer; Dactinomycin; Electrophoresis; Guinea Pigs; In Vitro Techniques; Orotic Acid; Paper; Phosphorus Isotopes; RNA; Tritium; Uracil; Uracil Nucleotides; Uridine

1967
Poly(A)-containing RNA in the livers of ethionine-treated rats.
    Canadian journal of biochemistry, 1980, Volume: 58, Issue:3

    Topics: Adenine; Animals; Ethionine; Fasting; Female; Liver; Orotic Acid; Poly A; Rats; RNA; Time Factors

1980
Phosphoribosylpyrophosphate bioavailability in diabetic rat renal cortex in vivo.
    The American journal of physiology, 1980, Volume: 238, Issue:4

    Topics: Adenine; Adenosine Triphosphate; Animals; Biological Availability; Diabetes Mellitus, Experimental; Infusions, Parenteral; Kidney Cortex; Male; Orotic Acid; Pentosephosphates; Phosphoribosyl Pyrophosphate; Rats; RNA; Uridine Triphosphate

1980
Alterations in glomerular RNA in diabetic rats: roles of glucagon and insulin.
    Kidney international, 1981, Volume: 20, Issue:4

    Topics: Adenine; Animals; Biotransformation; Diabetes Mellitus, Experimental; Glucagon; Glucose; Insulin; Kidney Glomerulus; Male; Orotic Acid; Rats; RNA; Streptozocin

1981
Influence of dietary purines on allopurinol metabolism and allopurinol induced oroticaciduria.
    Advances in experimental medicine and biology, 1984, Volume: 165 Pt A

    Topics: Adenine; Adenosine; Allopurinol; Diet; Humans; Hypoxanthine; Hypoxanthines; Male; Orotic Acid; Purines

1984
Fatty liver of growing rats fed excess lysine and its prevention by adenine or allopurinol.
    Lipids, 1981, Volume: 16, Issue:5

    Topics: Adenine; Allopurinol; Animals; Arginine; Diet; Fatty Liver; Lipid Metabolism; Liver; Lysine; Male; Orotic Acid; Rats

1981
Reduction of beta-oxidation capacity of rat liver mitochondria by feeding orotic acid.
    Biochimica et biophysica acta, 1982, Jun-11, Volume: 711, Issue:3

    Topics: Acyl-CoA Dehydrogenases; Adenine; Animals; Clofibric Acid; Diet; Fatty Acids; Fatty Liver; Male; Mitochondria, Liver; Orotic Acid; Oxidation-Reduction; Pantetheine; Rats; Rats, Inbred Strains

1982
Effect of some dietary additions to either an arginine-devoid diet or a diet supplemented with orotic acid refed after starvation on liver lipid content during essential fatty acid deficiency in rats.
    The Journal of nutrition, 1981, Volume: 111, Issue:5

    Topics: Adenine; Allopurinol; Animals; Arginine; Diet; Fatty Acids, Essential; Food; Lipid Metabolism; Liver; Male; Orotic Acid; Rats; Starvation

1981
[DNA methylation in wheat seedling and influence of phytohormones].
    Biokhimiia (Moscow, Russia), 1981, Volume: 46, Issue:1

    Topics: Adenine; Benzyl Compounds; Carbon Radioisotopes; Cytosine; DNA; Indoleacetic Acids; Kinetin; Methylation; Orotic Acid; Phenylacetates; Plant Growth Regulators; Plants; Purines; Triticum

1981
De novo synthesis of purine nucleotides in human blood platelets.
    Haemostasis, 1980, Volume: 9, Issue:1

    Topics: Adenine; Allopurinol; Azaserine; Blood Platelets; Formates; Humans; Hypoxanthines; Orotic Acid; Phosphoribosyl Pyrophosphate; Purine Nucleotides

1980
Telomere-associated chromosome breakage in fission yeast results in variegated expression of adjacent genes.
    The EMBO journal, 1994, Aug-15, Volume: 13, Issue:16

    Topics: Adenine; Cell Division; Chromosome Aberrations; DNA, Recombinant; Electrophoresis, Gel, Pulsed-Field; Extrachromosomal Inheritance; Gene Expression Regulation, Fungal; Gene Rearrangement; Genes, Fungal; Leucine; Orotic Acid; RNA, Fungal; Schizosaccharomyces; Uracil

1994
Effect of orotic acid on in vivo DNA synthesis in hepatocytes of normal rat liver and in hepatic foci/nodules.
    Carcinogenesis, 1993, Volume: 14, Issue:5

    Topics: Adenine; Animals; Diethylnitrosamine; DNA; DNA Replication; gamma-Glutamyltransferase; Glutathione Transferase; Hepatectomy; Kinetics; Liver; Liver Regeneration; Male; Orotic Acid; Rats; Rats, Inbred F344; Time Factors

1993
Metabolic effect of orotic acid in rat L6 myoblasts.
    Endocrine regulations, 1993, Volume: 27, Issue:3

    Topics: Adenine; Adenosylmethionine Decarboxylase; Animals; Bucladesine; Cell Division; Cell Line; Culture Media; DNA; Fetal Blood; Muscle Proteins; Muscles; Ornithine Decarboxylase; Orotic Acid; Putrescine; Rats; Spermine

1993
The effects of various inhibitors on the regulation of orotic acid excretion in sparse-fur mutant mice (spf/Y) deficient in ornithine transcarbamylase.
    Chemico-biological interactions, 1993, Volume: 89, Issue:1

    Topics: Adenine; Animals; Antimetabolites; Aspartic Acid; Creatinine; Cycloheximide; Injections, Intraperitoneal; Isoxazoles; Liver; Male; Mice; Mice, Mutant Strains; Ornithine; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Phosphonoacetic Acid

1993
Effect of orotic acid on beta 1,4-galactosyltransferase during liver regeneration.
    Carcinogenesis, 1993, Volume: 14, Issue:6

    Topics: Adenine; Animals; Galactosyltransferases; Hepatectomy; Kinetics; Liver Regeneration; Male; Orotic Acid; Rats; Rats, Inbred F344; RNA, Messenger

1993
Automated screening system for purine and pyrimidine metabolism disorders using high-performance liquid chromatography.
    Journal of chromatography. B, Biomedical applications, 1995, Oct-20, Volume: 672, Issue:2

    Topics: Adenine; Adenosine; Autoanalysis; Chromatography, High Pressure Liquid; Humans; Orotic Acid; Pseudouridine; Purine-Pyrimidine Metabolism, Inborn Errors; Uracil; Xanthine; Xanthines

1995
Antagonistic effect of nucleic acid precursors on the anticoccidial activity of 6-azauracil.
    The Journal of veterinary medical science, 1996, Volume: 58, Issue:2

    Topics: Adenine; Adenosine; Animals; Chickens; Coccidiosis; Coccidiostats; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance; Eimeria; Food, Fortified; Male; Nucleic Acid Precursors; Orotic Acid; Poultry Diseases; Uracil; Uridine

1996
Media formulations for various two-hybrid systems.
    Methods in molecular biology (Clifton, N.J.), 2001, Volume: 177

    Topics: Adenine; Carbon; Culture Media; Cycloheximide; Fungal Proteins; Genes, Reporter; Genetic Techniques; Genetic Vectors; Mycology; Orotic Acid; Protein Processing, Post-Translational; RNA, Fungal; Saccharomyces cerevisiae; Two-Hybrid System Techniques

2001
[Treatment of diseases of liver parenchyma; experiences with intravenous injections of a preparation containing a mixture of orotic acid and purines].
    Deutsche medizinische Wochenschrift (1946), 1956, Apr-13, Volume: 81, Issue:15

    Topics: Adenine; Humans; Injections, Intravenous; Liver Diseases; Orotic Acid; Purines; Xanthines

1956
Studies of the mechanism of action of urethane in initiating pulmonary adenomas in mice. II. Its relation to nucleic acid synthesis.
    The Journal of experimental medicine, 1957, Apr-01, Volume: 105, Issue:4

    Topics: Adenine; Adenoma; Animals; DNA; Lung Neoplasms; Mice; Neoplasms; Nucleic Acids; Orotic Acid; Pyrimidines; RNA; Thymine; Urethane

1957
[Effects of a new preparation of purinic and orotic acid base in chronic liver diseases].
    Gazzetta medica italiana, 1957, Volume: 116, Issue:5

    Topics: Adenine; Alkalies; Humans; Liver Diseases; Organic Chemicals; Orotic Acid; Xanthines

1957
Incorporation of adenine-8-C-14 and orotic-6-C-14 acid into nucleic acids of the feline neuraxis.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1958, Volume: 97, Issue:2

    Topics: Adenine; Animals; Cats; Central Nervous System; Nervous System; Nucleic Acids; Orotic Acid

1958
Uptake of adenine-8-C14 and orotic-6-C14 acid into nuclear DNA of non-dividing cells in the adult feline neuraxis.
    The Journal of biophysical and biochemical cytology, 1958, Sep-25, Volume: 4, Issue:5

    Topics: Adenine; Animals; Biochemical Phenomena; Cats; Central Nervous System; DNA; Nervous System; Orotic Acid

1958
[Experimental studies with liver-effective substances].
    Munchener medizinische Wochenschrift (1950), 1958, Aug-22, Volume: 100, Issue:34

    Topics: Adenine; Liver; Orotic Acid; Xanthines

1958
The effect of deoxyribonuclease on the incorporation of precursors into nuclear ribonucleic acid in reconstituted rat-liver homogenates.
    Biochimica et biophysica acta, 1962, Sep-17, Volume: 61

    Topics: Adenine; Animals; Deoxyribonucleases; DNA; Liver; Orotic Acid; Rats; RNA

1962
[Study of the reconstitution of nucleotides and ribonucleic acid in the crystalline lens].
    Journal de physiologie, 1963, Volume: 55

    Topics: Adenine; Glycine; Lens, Crystalline; Nucleotides; Orotic Acid; RNA

1963
Depression of plasma lipids in the rat by orotic acid and its reversal by adenine.
    Biochemical and biophysical research communications, 1963, Jun-20, Volume: 11

    Topics: Adenine; Animals; Depression; Lipids; Orotic Acid; Rats

1963
INHIBITORY ACTION OF ADENINE, ADENINENUCLEOSIDES AND NUCLEOTIDES ON THE BIOSYNTHESIS OF PORPHYRINS BY RHODOPSEUDOMONASSPHEROIDES.
    Nature, 1963, Sep-14, Volume: 199

    Topics: Adenine; Adenine Nucleotides; Adenosine Triphosphate; Antimetabolites; Chlorophyll; Levulinic Acids; Metabolism; Nucleosides; Nucleotides; Orotic Acid; Pharmacology; Porphyrins; Research; Rhodopseudomonas; Thymine; Uracil

1963
CHEMICAL REACTIVITY OF THE NUCLEIC ACID BASES. I. ANTIOXIDATIVE ABILITY OF THE NUCLEIC ACIDS AND THEIR RELATED SUBSTANCES ON THE OXIDATION OF UNSATURATED FATTY ACIDS.
    Archives of biochemistry and biophysics, 1963, Volume: 102

    Topics: Adenine; Antioxidants; Catechols; Citrates; Copper; Diphosphates; Fats, Unsaturated; Fatty Acids, Unsaturated; Linoleic Acid; Lipid Metabolism; Nucleic Acids; Nucleosides; Orotic Acid; Oxidation-Reduction; Research; RNA; Uracil; Uric Acid; Vitamin E; Xanthines

1963
[INHIBITORY ACTION OF NUCLEOSIDES AND ADENINE NUCLEOTIDES ON THE BIOSYNTHESIS OF PORPHYRINS BY RHODOPSEUDOMONAS SPHEROUIDES].
    Bulletin de la Societe de chimie biologique, 1963, Oct-04, Volume: 45

    Topics: Adenine; Adenine Nucleotides; Adenosine Triphosphate; Antimetabolites; Glycine; Ketoglutaric Acids; Levulinic Acids; Nucleosides; Orotic Acid; Pharmacology; Porphyrins; Research; Rhodopseudomonas; Succinates; Thymidine; Thymine; Uracil

1963
[ON THE EXISTENCE OF RAPIDLY LABELED DESOXYRIBONUCLEIC FRACTION IN ANIMAL CELLS].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1964, Feb-10, Volume: 258

    Topics: Adenine; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; DNA; Liver; Liver Neoplasms; Neoplasm Proteins; Neoplasms, Experimental; Orotic Acid; Radiometry; Research; Thymidine; Tritium

1964
PURINE METABOLISM OF UNICELLULAR ALGAE. I. CHROMATOGRAPHIC DETECTION OF SOME PURINES, PYRIMIDINES, AND IMIDAZOLES BY THEIR MERCURIC COMPLEXES.
    Analytical biochemistry, 1964, Volume: 7

    Topics: Adenine; Alloxan; Chromatography; Creatine; Creatinine; Eukaryota; Guanine; Hydantoins; Hypoxanthines; Imidazoles; Mercury; Orotic Acid; Purines; Pyrimidines; Research; Ultraviolet Rays; Uric Acid; Xanthines

1964
INHIBITION OF DNA SYNTHESIS IN MAMMALIAN CELLS BY ACTIDIONE.
    Biochimica et biophysica acta, 1964, May-18, Volume: 87

    Topics: Adenine; Adenine Nucleotides; Anti-Bacterial Agents; Aspartic Acid; Carbon Isotopes; Carcinoma, Squamous Cell; Cycloheximide; Cytosine Nucleotides; DNA; DNA Replication; DNA, Neoplasm; Formates; Glycine; Guanine Nucleotides; Leucine; Metabolism; Neoplasms; Nucleosides; Nucleotides; Nucleotidyltransferases; Orotic Acid; Pharmacology; Research; RNA; RNA, Neoplasm; Thymidine; Tissue Culture Techniques; Tritium

1964
AN OROTIC ACID-INDUCED, ADENINE-REVEREED INHIBITION OF HEPATIC LIPOPROTEIN SECRETION IN THE RAT.
    The Journal of biological chemistry, 1964, Volume: 239

    Topics: Adenine; Adipose Tissue; Antimetabolites; Cholesterol; Fatty Acids; Fatty Liver; Glycerides; Intestines; Lipid Metabolism; Lipoproteins; Liver; Mesentery; Orotic Acid; Pharmacology; Phospholipids; Rats; Research; Surface-Active Agents; Tritium

1964
FORMATION OF RIBOMONONUCLEOTIDES FROM PURINE AND PYRIMIDINE BASES AND 5'-PHOSPHORIBOSYLPYROPHOSPHATE BY A SALMON MILT EXTRACT.
    Canadian journal of biochemistry, 1964, Volume: 42

    Topics: Adenine; Adenine Nucleotides; Animals; Carbon Isotopes; Chromatography; Cytosine; Cytosine Nucleotides; Diphosphates; Fishes; Guanine; Guanine Nucleotides; Metabolism; Nucleotides; Orotic Acid; Phosphoribosyl Pyrophosphate; Purines; Pyrimidines; Research; Salmon; Thymine; Tissue Extracts; Tritium; Uracil; Uracil Nucleotides; Xanthines

1964
URACIL METABOLISM IN TADPOLES DURING THYROXINE-INDUCED METAMORPHOSIS.
    The Journal of biological chemistry, 1964, Volume: 239

    Topics: Adenine; Animals; Anura; Carbamates; Cytosine; Glucosyltransferases; Larva; Ligases; Liver; Metabolism; Metamorphosis, Biological; Nucleosides; Orotic Acid; Pharmacology; Phosphates; Ranidae; Research; Thyroxine; Uracil

1964
PERIPORTAL FATTY LIVER IN THE RAT INDUCED BY HIGH PROTEIN OROTIC ACID DIETS.
    The Indian journal of medical research, 1964, Volume: 52

    Topics: Adenine; Diet; Dietary Proteins; Fatty Liver; Orotic Acid; Pharmacology; Rats; Research; Toxicology

1964
[STUDY OF THE PASSAGE OF CERTAIN PRECURSORS OF NUCLEIC ACIDS FROM THE CEREBROSPINAL FLUID INTO THE CENTRAL NERVOUS SYSTEM].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1964, Volume: 158

    Topics: Adenine; Blood; Blood-Brain Barrier; Carbon Isotopes; Guanine; Nucleic Acids; Nucleosides; Nucleotides; Orotic Acid; Physiology; Radiometry; Rats; Research; Uracil; Uridine

1964
HEPATIC NUCLEOTIDE LEVELS AND NAD-SYNTHESIS AS INFLUENCED BY DIETARY OROTIC ACID AND ADENINE.
    The Journal of nutrition, 1965, Volume: 85

    Topics: Adenine; Adenine Nucleotides; Diet; Guanine Nucleotides; Lipids; Liver; Metabolism; NAD; Niacin; Niacinamide; Nicotinic Acids; Nucleotides; Orotic Acid; Rats; Research; Spectrum Analysis; Uracil Nucleotides

1965
EFFECTS OF THIOACETAMIDE ON NUCLEAR AND NUCLEOLAR RNA OF THE RAT LIVER.
    Texas reports on biology and medicine, 1965, Volume: 23

    Topics: Adenine; Amides; Anesthetics, Local; Carbon Isotopes; Cell Nucleolus; Cell Nucleus; Cytosine; Guanine; Liver; Metabolism; Orotic Acid; Rats; Research; RNA; Sulfhydryl Compounds; Thioacetamide; Uracil

1965
THE EFFECTS OF 3'-DEOXYADENOSINE ON THE SYNTHESIS OF RIBONUCLEIC ACID.
    The Journal of biological chemistry, 1965, Volume: 240

    Topics: Adenine; Adenosine Triphosphate; Antimetabolites; Antineoplastic Agents; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cytosine Nucleotides; Deoxyadenosines; Formates; Glycine; Guanine; Metabolism; Mice; Neoplasms; Nucleosides; Nucleotidyltransferases; Orotic Acid; Pharmacology; Polynucleotides; Research; RNA; RNA, Neoplasm; Tissue Culture Techniques; Uracil Nucleotides; Xanthines

1965
METABOLIC EFFECTS OF AN ANTIBIOTIC, NSC-51954, ON SUSCEPTIBLE AND RESISTANT TUMOR CELLS.
    Cancer research, 1965, Volume: 25

    Topics: Adenine; Animals; Anti-Bacterial Agents; Carbon Isotopes; Carcinoma, Ehrlich Tumor; DNA; DNA, Neoplasm; Guanine; Guanine Nucleotides; Leukemia; Leukemia, Experimental; Mice; Neoplasm Proteins; Neoplasms; Orotic Acid; Pharmacology; Phosphotransferases; Proteins; Radiometry; Research; RNA; RNA, Neoplasm; Sarcoma 180; Toxicology; Uracil

1965
EFFECT OF AZASERINE ON THE INCORPORATION OF 14-C-LABELED PURINES AND PYRIMIDINES INTO ACID-SOLUBLE AND NUCLEIC ACID FRACTIONS OF TRYPANOSOMA EQUIPERDUM.
    Biochemical pharmacology, 1965, Volume: 14

    Topics: Adenine; Amino Acids; Azaserine; Cytosine; Cytosine Nucleotides; DNA; Glutamine; Guanine; Hypoxanthines; Leucine; Metabolism; Nucleic Acids; Orotic Acid; Pharmacology; Purines; Pyrimidines; Research; RNA; Thymine; Trypanosoma; Tryptophan; Tyrosine; Uracil; Uracil Nucleotides

1965
METABOLISM OF TISSUE CELLS IN SUSPENSION. SYNTHESIS OF RIBONUCLEIC ACID BY LEIVER CELLS IN SUSPENSION.
    The Biochemical journal, 1965, Volume: 95

    Topics: Adenine; Liver; Metabolism; Orotic Acid; Phosphates; Rats; Research; RNA; Uracil

1965