adenine has been researched along with orotic acid in 136 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 124 (91.18) | 18.7374 |
1990's | 10 (7.35) | 18.2507 |
2000's | 1 (0.74) | 29.6817 |
2010's | 1 (0.74) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Dragún, M; Rada, B | 1 |
Bhargava, PM; Bornecque, CA; Szafarz, D; Zajdela, F | 1 |
Christopherson, RI; Finch, LR | 1 |
Milner, JA | 1 |
Cox, RP; Holland, MJ; Klein, NC | 1 |
Cameron, JS; McBurney, A; Simmonds, HA; Van Acker, KJ | 1 |
Geshanova, E; Zhivkov, V | 1 |
Bakanova, NV; Leutskií, KM | 1 |
Henderson, GI; Schenker, S | 1 |
Kumar, A; Malt, RA; Ouellette, AJ | 1 |
Balavoine, S; Feldmann, G; Lardeux, B; Rogier, E | 1 |
Nelson, J; Qureshi, IA; Vasudevan, S | 1 |
Kato, S; Kitada, T; Morichi, T; Suzuki, I; Yano, N | 1 |
Fairbanks, LD; Simmonds, HA; Webster, DR | 1 |
Lee, GS; Ritzel, RG; Savage, EA; von Borstel, RC | 1 |
Ord, MG; Stocken, LA | 2 |
Carr, J; Hollingsworth, JW | 1 |
Hosono, R; Kuno, S | 1 |
Kummer, D | 1 |
Fox, IH; Kelley, WN | 3 |
Sidransky, H; Verney, E; Wagle, DS | 1 |
Sprecher-Goldberger, S | 1 |
Doremus, HM; Jaffe, JJ | 1 |
Fox, IH; Greene, ML; Kelley, WN; Levy, RI; Rosenbloom, FM; Seegmiller, JE | 1 |
Chudinova, IA; Davidova, SY; Gorozhanskaya, EG; Krechetova, GD; Shapot, VS; Vornovitskaya, GI; Zhubanova, AA | 1 |
Beardmore, TD; Kelley, WN; Meade, JC | 1 |
Bagnara, AS; Finch, LR | 1 |
Hüttermann, J; Müller, A | 1 |
Bagnara, AS; Brox, LW; Henderson, JF | 1 |
Feigelson, M; Feigelson, P | 1 |
Christow, CP | 1 |
Brykina, EV; Chernovskaya, TV; Lerman, MI; Podobed, OV | 1 |
Bociat, T; Capusan, I; Lazar, V; Moisi, IG; Opincaru, E | 1 |
Farber, JL; Farmar, R; Serroni, A; Shinozuka, H | 1 |
Jacobs, RL; Koontz, LC; Miller, LH | 1 |
Riede, UN; Rohr, HP | 1 |
Becker, MA; Seegmiller, JE | 1 |
Exinger, F; Korch, CT; Lacroute, F | 1 |
Gleeson, RA; Hill, RN; Smith, SJ; Vesell, ES | 1 |
Howell, BA; Kizer, DE | 1 |
Booden, T; Hull, RW | 1 |
Dewey, VC; Kidder, GW | 1 |
Coleman, RD; Hardy, D; Hurlbert, RB; Stankovich, M | 1 |
Elaev, NR | 1 |
Farber, JL; Konishi, Y; Shinozuka, H | 1 |
Camakaris, J; Cotton, RG; Danks, DM | 1 |
Clouse, JA; Kizer, DE | 2 |
Barr, CF; Polet, H | 1 |
Mandel, HG; Szapáry, D; Triester, SR | 1 |
Cerna, I; Fay, PJ; Klubes, P | 1 |
Chlumský, J; Hyncík, V | 1 |
Trager, W | 1 |
Gelderman, AH; Keister, DB; Perrotto, J | 1 |
Koenig, E | 1 |
Buchowicz, J; Grzelczak, Z | 1 |
Chou, JY; Dickman, SR | 1 |
Heath, RL | 1 |
Kaneko, T; LePage, GA | 1 |
Kelley, WN; Wyngaarden, JB | 1 |
Marchetti, M; Moruzzi, G | 1 |
Fox, RM; O'Sullivan, WJ; Wood, MH | 1 |
Hori, M; Kunimoto, T; Sawa, T; Umezawa, H; Wakashiro, T | 1 |
Dianzani, MU; Torrielli, MV; Ugazio, G | 1 |
Matolcsy, G; Pozsár, BI | 1 |
Hempstead, KW; Kopp, LE; Miech, RP; Santos, JN | 1 |
Harris, EJ; Manchester, KL | 1 |
Farber, E; Stewart, GA | 1 |
Drews, J | 1 |
Klatskin, G; Scheig, R; Simon, JB | 2 |
Held, I; Koenig, H; Wells, W | 1 |
Adams, WR; Handschumacher, RE; Rajalakshmi, S | 1 |
Fausto, N | 1 |
Gillette, JR; Holtzman, JL | 1 |
Caldarera, CM; Marchetti, M; Puddu, P | 1 |
Busch, H; Muramatsu, M | 1 |
Spaeth, AE; Windmueller, HG | 1 |
Farber, E; Shull, KH; Villa-Trevino, S | 1 |
Groth, DP; Jiang, N | 1 |
Adams, DH | 1 |
Sartorelli, AC; Tsunamura, S | 1 |
Georg, D; Mähr, G; Rommel, K; Török, M | 1 |
Arion, VJ; Georgiev, GP; Mantieva, VL | 1 |
Barry, JM; Leader, DP | 1 |
Cachin, M; Charbonnier, A; Lafille, C; Rousselot, P | 1 |
Manchester, KL | 1 |
Cain, DF | 1 |
Dennis, J; Kisilevsky, R | 1 |
Cortes, P; Levin, NW; Schoenberger, AM; Venkatachalam, KK; Verghese, CP | 1 |
Bernstein, J; Cortes, P; Dumler, F; Goldman, J; Levin, NW; Sastry, KS; Venkatachalam, H; Venkatachalam, KK | 1 |
Gröbner, W; Löffler, W; Reiter, S; Zöllner, N | 1 |
Ifft, KH; Kari, FW; Ulman, EA; Visek, WJ | 1 |
Furuta, S; Hashimoto, T; Miyazawa, S | 1 |
Aoyama, Y; Ashida, K; Yoshida, A | 1 |
Bashkite, EA; Fridrikh, A; Khovĭka, LA; Vaniushin, BF | 1 |
Boer, P; Jerushalmy, Z; Patya, M; Sperling, O | 1 |
Allshire, RC; Cranston, G; Nimmo, ER | 1 |
Laconi, E; Rajalakshmi, S; Rao, PM; Sarma, DS; Sheikh, A; Yusuf, A | 1 |
Blachowski, S; Grzelkowska, K; Kasterka, M; Motyl, T | 1 |
Nelson, J; Qureshi, IA; Sarma, DS; Vasudevan, S | 1 |
Narasimhan, S; Pascale, RM; Rajalakshmi, S; Sharma, RK | 1 |
Kidouchi, K; Ohba, S; Sumi, S; Wada, Y | 1 |
Hariguchi, F; Hayashi, T; Kobayashi, N; Matsuno, T; Okada, Y; Okamoto, T | 1 |
Zimmer, HG | 1 |
Gautsch, J; Hoekstra, D; Saghbini, M | 1 |
BECKMANN, K; BRUGEL, H; MERTZ, DP | 1 |
ROGERS, S | 1 |
ALLODI, A; MURATORI, F | 1 |
KOENIG, H | 2 |
KIPPING, H | 1 |
NAYFEH, SN; SCHNEIDER, JH | 1 |
KLETHI, J; MANDEL, P; VIRMAUX, N | 1 |
WINDMUELLER, HG | 3 |
GAJDOS, A; GAJDOS-TOEROEK, M | 2 |
AOKI, A; IBUKI, F; MATSUSHITA, S | 1 |
BORKOWSKA, I; MANDEL, L; MANDEL, P; WINTZERITH, M | 1 |
AMMANN, EC; LYNCH, VH | 1 |
BENNETT, LL; SMITHERS, D; WARD, CT | 1 |
TARR, HL | 1 |
AKAMATSU, N; COHEN, PP; LINDSAY, RH | 1 |
RAJALAKSHMI, S; SARMA, DS; SARMA, PS; SRIRAMACHARI, S | 1 |
MANDEL, P; MICHAELIDIS, P | 1 |
ADAMS, HR; BUSCH, H | 1 |
GORDON, CN; SHIGEURA, HT | 1 |
LEPAGE, GA; SATO, K | 1 |
JAFFE, JJ; MOMPARLER, RL | 1 |
BHARGAVA, PM; JACOB, ST | 1 |
5 review(s) available for adenine and orotic acid
Article | Year |
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Phosphoribosylpyrophosphate in man: biochemical and clinical significance.
Topics: Adenine; Adrenocorticotropic Hormone; Allopurinol; Animals; Glycogen; Gout; Humans; Lesch-Nyhan Syndrome; Methylene Blue; Orotic Acid; Pentosephosphates; Phosphoric Acids; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Ribose; Thiadiazoles; Thyrotropin; Transferases; Urate Oxidase; Uric Acid | 1971 |
Notes on some peculiarities of enzymic processes in malignant tumours and tissues of the host.
Topics: Adenine; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Catalase; Cholesterol; DNA, Neoplasm; Humans; Isoenzymes; L-Lactate Dehydrogenase; Leukemia, Lymphoid; Leukemia, Myeloid; Leukocytes; Liver; Liver Neoplasms; Lymphocytes; Neoplasms; Neoplasms, Experimental; Orotic Acid; Pyrimidine Nucleotides; Rats; RNA, Neoplasm; Uracil | 1972 |
[The reaction pattern of liver-peroxysomes (equal microbodies) during cell-injury (author's transl)].
Topics: Adenine; Aspirin; Chloramphenicol; Cycloheximide; Epinephrine; Folic Acid; Liver; Microbodies; Mitochondria; Mitochondria, Liver; Mitochondrial Swelling; Organoids; Orotic Acid; Penicillamine; Vitamin D Deficiency | 1974 |
Genetic aspects of gout.
Topics: Adenine; Allopurinol; Carbon Radioisotopes; Erythrocytes; Fibroblasts; Glucosephosphate Dehydrogenase; Glutamine; Glutathione Reductase; Gout; Guanine; Humans; Hypoxanthines; Lesch-Nyhan Syndrome; Liver; Metabolic Diseases; Molecular Weight; Orotic Acid; Pentosyltransferases; Purines; Uric Acid; Xanthine Oxidase | 1974 |
Significance of the 5-phosphoribosyl-1-pyrophosphate pool for cardiac purine and pyrimidine nucleotide synthesis: studies with ribose, adenine, inosine, and orotic acid in rats.
Topics: Adenine; Animals; Inosine; Myocardium; Orotic Acid; Phosphoribosyl Pyrophosphate; Purine Nucleotides; Pyrimidine Nucleotides; Rats; Ribose | 1998 |
131 other study(ies) available for adenine and orotic acid
Article | Year |
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Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Inhibition of Newcastle disease virus replication by 6-azauridine. II. Combination of 6-azauridine and adenine derivatives.
Topics: Adenine; Azauridine; Culture Techniques; Drug Synergism; Newcastle disease virus; Orotic Acid; Purine Nucleosides; Purine Nucleotides; Pyrimidine Nucleosides; Pyrimidine Nucleotides; Virus Replication | 1976 |
Uptake in vitro of nucleic acid precursors and nucleic acids by Zajdela ascitic hepatoma cells.
Topics: Adenine; Animals; Biological Transport, Active; Carcinoma, Hepatocellular; Cell Line; DNA; DNA, Bacterial; Liver; Liver Neoplasms; Orotic Acid; Rats; Ribonucleosides; RNA; RNA, Bacterial; Uracil; Uridine | 1975 |
Response of the pyrimidine pathway of Escherichia coli K 12 to exogenous adenine and uracil.
Topics: Adenine; Aspartate Carbamoyltransferase; Aspartic Acid; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Carbamyl Phosphate; Escherichia coli; Kinetics; Orotate Phosphoribosyltransferase; Orotic Acid; Pyrimidines; Uracil | 1978 |
Mechanism for fatty liver induction in rats fed arginine deficient diets.
Topics: Adenine; Animals; Arginine; Body Weight; Cholesterol; Citrates; Fatty Liver; Female; Guanine; Lipid Metabolism; Male; Orotic Acid; Phospholipids; Rats; Triglycerides; Urea | 1979 |
Experimental modulation of PRPP availability for ribonucleotide synthesis from hypoxanthine in human skin fibroblast cultures.
Topics: Adenine; Adenosine; Cell Line; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Kinetics; Methylene Blue; Orotic Acid; Pentosephosphates; Phosphoribosyl Pyrophosphate; Ribonucleotides | 1978 |
Purine excretion in complete adenine phosphoribosyltransferase deficiency: effect of diet and allopurinol therapy.
Topics: Adenine; Adenine Phosphoribosyltransferase; Allopurinol; Child, Preschool; Diet; Humans; Male; Orotic Acid; Pentosyltransferases; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Uric Acid | 1977 |
(14C)-precursors incorporation into adenine and uridine nucleotides of the liver of some vertebrates.
Topics: Adenine; Adenosine Monophosphate; Animals; Carbon Radioisotopes; Chickens; Columbidae; Glycine; Guinea Pigs; Liver; Male; Orotic Acid; Phosphates; Phosphorus Radioisotopes; Rats; Species Specificity; Uracil Nucleotides | 1975 |
[The effect of orotic acid and vitamin A on 2C-14-orotic acid incorporation into the acid-soluble fraction and nucleic acids of white rat tissues].
Topics: Adenine; Animals; Brain; Brain Chemistry; Carbon Radioisotopes; DNA; Guanine; Kidney; Liver; Male; Orotic Acid; Rats; RNA; Spleen; Testis; Uracil; Vitamin A | 1975 |
Reversible impairment of cerebral DNA synthesis in thiamine deficiency.
Topics: Adenine; Animals; Brain; Brain Diseases; Carbon Radioisotopes; DNA; Female; Hypothermia; Organ Size; Orotic Acid; Proteins; Rats; RNA; Thiamine; Thiamine Deficiency; Thymidine; Tritium | 1975 |
Physical aspects and cytoplasmic distribution of messenger RNA in mouse kidney.
Topics: Adenine; Animals; Centrifugation, Density Gradient; Cytoplasm; Kidney; Male; Mice; Molecular Weight; Orotic Acid; Poly A; Polyribosomes; Rats; RNA, Messenger | 1976 |
Responsiveness of RNA degradation to amino acids in cultured rat hepatocytes: comparison with isolated rat hepatocytes.
Topics: Adenine; Amino Acids; Animals; Cell Count; Cells, Cultured; Culture Media; Kinetics; Liver; Male; Microscopy, Electron; Orotic Acid; Radioactivity; Rats; RNA | 1992 |
[Mechanism of the effect of serine and threonine on ammoniagenesis and biosynthesis of orotate in the mouse].
Topics: Adenine; Ammonia; Animals; Aspartic Acid; Cycloheximide; Male; Mice; Mice, Inbred ICR; Orotic Acid; Phosphonoacetic Acid; Serine; Threonine | 1992 |
Growth of Lactobacillus bulgaricus in milk. 2. Characteristics of purine nucleotides, pyrimidine nucleotides, and nucleic acid synthesis.
Topics: Adenine; Adenosine Monophosphate; Animals; Cattle; DNA, Bacterial; Guanine; Guanosine Monophosphate; In Vitro Techniques; Lactobacillus; Milk; Orotic Acid; Purine Nucleotides; RNA, Bacterial | 1986 |
Usefulness of intact erythrocyte studies in the diagnosis of inherited purine and pyrimidine defects.
Topics: Adenine; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Deoxyadenosines; Erythrocytes; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Orotic Acid; Phosphoribosyl Pyrophosphate; Purine-Pyrimidine Metabolism, Inborn Errors; Radioisotope Dilution Technique | 1986 |
The base-alteration spectrum of spontaneous and ultraviolet radiation-induced forward mutations in the URA3 locus of Saccharomyces cerevisiae.
Topics: Adenine; Base Sequence; Cyclobutanes; DNA Mutational Analysis; DNA, Fungal; Genes, Fungal; Genetic Vectors; Orotic Acid; Plasmids; Pyrimidine Dimers; Saccharomyces cerevisiae; Ultraviolet Rays | 1988 |
Uptake of amino acids and nucleic acid precursors by regenerating rat liver.
Topics: Adenine; Adrenalectomy; Amino Acids; Animals; Dactinomycin; Hepatectomy; Liver; Liver Regeneration; Lysine; Male; Ornithine; Orotic Acid; Phenylalanine; Rats; RNA; Thymidine; Tritium; Tyrosine; Uridine; Valine | 1972 |
3H-uridine incorporation as a T lymphocyte indicator in the rat.
Topics: Adenine; Adenosine; Animals; Ascitic Fluid; Autoradiography; Cycloheximide; Cytidine; Dactinomycin; Female; Lymphocyte Depletion; Lymphopenia; Male; Orotic Acid; Phosphorus Isotopes; Polyethylenes; Puromycin; Rats; Rats, Inbred Strains; T-Lymphocytes; Thoracic Duct; Tritium; Uridine | 1973 |
Mechanism of inhibition of bacterial growth by adenine.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Bacterial Proteins; Carbon Radioisotopes; Culture Media; Depression, Chemical; DNA, Bacterial; Edetic Acid; Escherichia coli; Guanosine; Inosine; Orotic Acid; Oxygen Consumption; Phosphorus Radioisotopes; Purine Nucleotides; Pyrimidine Nucleotides; RNA, Bacterial; Uridine | 1974 |
[Effects of cytostatics and x-rays on nucleic acid metabolism of solid, malignant tumors in vitro].
Topics: Adenine; Animals; Antineoplastic Agents; Carbon Isotopes; Dactinomycin; Depression, Chemical; DNA, Neoplasm; Estriol; Fluorouracil; Formates; Glycine; Hypoxanthines; In Vitro Techniques; Leucine; Mercaptopurine; Methotrexate; Methylprednisolone; Neoplasm Proteins; Neoplasms, Experimental; Nucleosides; Orotic Acid; Radiation Effects; RNA, Neoplasm; Testosterone; Thymidine; Triaziquone; Uracil; Uridine | 1970 |
Pharmacological alterations of intracellular phosphoribosylpyrophosphate (PP-ribose-P) in human tissues.
Topics: Adenine; Allopurinol; Deoxy Sugars; Erythrocytes; Fibroblasts; Glucose; Guanine Nucleotides; Humans; Inosine Nucleotides; Methylene Blue; Niacinamide; Nicotinic Acids; Orotic Acid; Pentosephosphates; Pentosyltransferases; Purines; Skin; Time Factors | 1973 |
Effect of dietary orotic acid on liver glycogen.
Topics: Adenine; Animals; Epinephrine; Fatty Liver; Glucose-6-Phosphatase; Glucosidases; Glycine; In Vitro Techniques; Liver; Liver Glycogen; Orotic Acid; Phosphotransferases; Rats; Sucrose | 1965 |
The existence of two different metabolic patterns for the synthesis of RNA viruses.
Topics: Adenine; Animals; Antimetabolites; Chick Embryo; Culture Media; Dactinomycin; Enterovirus; Fibroblasts; Formates; Histones; Influenza A virus; Methotrexate; Nucleosides; Orotic Acid; Phenylalanine; Puromycin; Radiation Effects; RNA Viruses; RNA, Viral; Thymidine; Ultraviolet Rays; Uridine | 1966 |
Metabolic patterns of Dirofilaria immitis microfilariae in vitro.
Topics: Adenine; Amino Acids; Animals; Benzenesulfonates; Carbon Dioxide; Carbon Isotopes; Diethylcarbamazine; Dithiazanine; DNA; Filarioidea; Formates; Glucose; Glycine; Glycogen; In Vitro Techniques; Lipid Metabolism; Orotic Acid; Proteins; RNA; Uracil; Uridine | 1970 |
Effects of orotic acid on purine and lipoprotein metabolism in man.
Topics: Adenine; Administration, Oral; Carbon Isotopes; Cholesterol; Diphosphates; Erythrocytes; Glycine; Guanine; Humans; Kidney; Lipoproteins; Metabolic Clearance Rate; Nitrogen; Orotic Acid; Purines; Radioisotopes; Ribose; Transferases; Triglycerides; Uric Acid | 1970 |
Increased activity of two enzymes of pyrimidine biosynthesis de novo in erythrocytes from patients with the Lesch-Nyhan syndrome.
Topics: Adenine; Adolescent; Allopurinol; Carbon Isotopes; Carboxy-Lyases; Child; Child, Preschool; Diphosphates; Erythrocyte Aging; Erythrocytes; Hot Temperature; Humans; Infant; Lesch-Nyhan Syndrome; Orotic Acid; Pentosyltransferases | 1973 |
The effects of bases and nucleosides on the intracellular contents of nucleotides and 5-phosphoribosyl 1-pyrophosphate in Escherichia coli.
Topics: Adenine; Adenine Nucleotides; Adenosine; Carbon Radioisotopes; Cytosine Nucleotides; Escherichia coli; Guanine; Guanine Nucleotides; Guanosine; Hypoxanthines; Inosine; Inosine Nucleotides; Kinetics; Organophosphorus Compounds; Orotic Acid; Pentosephosphates; Phosphoric Acids; Ribonucleosides; Ribonucleotides; Time Factors; Uracil; Uracil Nucleotides; Uridine | 1974 |
Structure and formation of free radicals in irradiated single crystals of nucleic acid constituents.
Topics: Adenine; Barbiturates; Bromodeoxyuridine; Crystallization; Electron Spin Resonance Spectroscopy; Free Radicals; Guanine; Idoxuridine; Molecular Conformation; Orotic Acid; Purines; Pyrimidines; Radiation Effects; Structure-Activity Relationship; Thymine; Uracil | 1973 |
Observations of altered intracellular phosphoribosylpyrophosphate (PP-ribose-P) in human disease.
Topics: Adenine; Carbon Radioisotopes; Erythrocytes; Fibroblasts; Formates; Gout; Guanine Nucleotides; Heterozygote; Homozygote; Humans; Inosine Nucleotides; Methylene Blue; Orotic Acid; Pentosephosphates; Pentosyltransferases; Phosphoric Acids; Ribonucleotides; Uric Acid | 1974 |
Kinetics of amidophosphoribosyltransferase in intact tumor cells.
Topics: Adenine; Animals; Azo Compounds; Carbon Radioisotopes; Carcinoma, Ehrlich Tumor; Chromatography, Ion Exchange; Chromatography, Paper; Glutamine; Kinetics; Orotic Acid; Pentosephosphates; Pentosyltransferases; Phosphoric Acids; Spectrophotometry; Time Factors | 1974 |
Relationships between hepatic enzyme induction, glutamate formation, and purine nucleotide biosynthesis in glucocorticoid action.
Topics: Adenine; Animals; Cortisone; Enzyme Induction; Glutamates; Glycine; In Vitro Techniques; Liver; Nucleotides; Orotic Acid; Rats; RNA; Spleen; Thymus Gland; Transaminases; Tyrosine Transaminase; Uracil Nucleotides | 1966 |
[Experiments on the influence of metabolites and antimetabolites on the model of Trichomonas vaginalis. V. Relationship between vitamin-B-complexes and Trichomonas vaginalis].
Topics: Adenine; Adenosine Monophosphate; Bacteriological Techniques; Biotin; Carnitine; Choline; Hydrogen-Ion Concentration; Inositol; Models, Biological; Orotic Acid; Pyridoxine; Riboflavin; Thiamine; Thioctic Acid; Trichomonas vaginalis; Vitamin B Complex; Xanthopterin | 1971 |
Lack of correlation between the lifetimes of mRNA and the initial lengths of their poly A segments.
Topics: Adenine; Adenosine Monophosphate; Animals; Base Sequence; Carbon Radioisotopes; Dactinomycin; Drug Stability; Electrophoresis, Polyacrylamide Gel; Isotope Labeling; Kinetics; Liver; Mice; Molecular Weight; Orotic Acid; Pancreas; Polyribosomes; Ribonucleases; Ribonucleotides; RNA, Messenger; Time Factors | 1974 |
[Purinor in the treatment of porphyria cutanea tarda].
Topics: Adenine; Adult; Alanine Transaminase; Aspartate Aminotransferases; Drug Combinations; Fructosephosphates; Humans; Hypoxanthines; Inositol; Magnesium; Male; Middle Aged; Orotic Acid; Porphyrias; Porphyrins; Purines; Xanthines | 1974 |
Reversal of the ethionine-induced inhibition of rat liver ribonucleic acid polymerases in vivo by adenine.
Topics: Adenine; Animals; Carbon Radioisotopes; Cell Nucleus; Chromatography, DEAE-Cellulose; Cycloheximide; Depression, Chemical; DNA; DNA-Directed RNA Polymerases; Enzyme Inhibitors; Ethionine; Female; Leucine; Liver; Methionine; Mycotoxins; Oligopeptides; Orotic Acid; Peptides, Cyclic; Rats; RNA; Solubility; Tritium | 1974 |
Labeling of sporozoites of Plasmodium berghei with tritiated purines.
Topics: Adenine; Adenosine; Animals; Anopheles; Blood; Deoxyadenosines; Deoxyribonucleosides; Guanosine; Isotope Labeling; Malaria; Mice; Orotic Acid; Plasmodium berghei; Purines; Salivary Glands; Thymidine; Tritium | 1974 |
A regulatory interaction between pyrimidine and purine biosyntheses via ureidosuccinic acid.
Topics: Adenine; Aspartic Acid; Carbamates; Cytosine; Drug Resistance, Microbial; Mutation; Orotic Acid; Phenotype; Purines; Pyrimidines; Saccharomyces cerevisiae; Uracil | 1974 |
Evidence for post-transcriptional stabilization of ribosomal precursor ribonucleic acid by phenobarbital.
Topics: Adenine; Animals; Carbon Isotopes; Cell Nucleolus; Cell Nucleus; Centrifugation, Density Gradient; Chromatography; DNA; Drug Stability; Guanine; Liver; Male; Microsomes, Liver; Orotic Acid; Phenobarbital; Rats; RNA, Ribosomal; Sucrose; Transcription, Genetic; Tritium; Uracil Nucleotides | 1972 |
Nucleic acid precursor uptake into normal and regenerating rat liver.
Topics: Adenine; Animals; Carbon Isotopes; DNA; Inulin; Liver; Liver Regeneration; Orotic Acid; Rats; RNA; Thymidine; Tritium; Uracil Nucleotides | 1972 |
Synchrony between DNA synthesis and thymidine incorporation into DNA in regenerating rat liver.
Topics: Adenine; Animals; Aspartic Acid; Carbon Isotopes; Chromatography, DEAE-Cellulose; DNA; Female; Formates; Hydrocortisone; Hydrolysis; In Vitro Techniques; Liver; Liver Regeneration; Orotic Acid; Proteins; Rats; Stress, Physiological; Thymidine; Thymidine Kinase; Time Factors; Tritium | 1973 |
Nucleic acid precursor synthesis by Plasmodium lophurae parasitizing chicken erythrocytes.
Topics: Adenine; Animals; Autoradiography; Carbon Radioisotopes; Chickens; Culture Media; DNA; Erythrocytes; Formates; Glycine; Malaria, Avian; Male; Orotic Acid; Plasmodium; Purine Nucleotides; Pyrimidine Nucleotides; RNA; Spectrophotometry; Thymidine; Tritium; Uracil; Uridine | 1973 |
The sites of action of allopurinol in Crithidia fasciculata.
Topics: Adenine; Allopurinol; Animals; Carbon Radioisotopes; Cell-Free System; Chemical Phenomena; Chemistry; Chromatography, Paper; Colorimetry; Cytosine; Dose-Response Relationship, Drug; Eukaryota; Folic Acid; Guanine; Hypoxanthines; Orotic Acid; Pentosyltransferases; Pterins; Spectrophotometry; Uracil; Xanthines | 1973 |
Mechanism of turnover of rapidly labeled RNA in rat liver nuclei.
Topics: Adenine; Animals; Carbon Radioisotopes; Cell Nucleus; Cytoplasm; Female; In Vitro Techniques; Liver; Methods; Orotic Acid; Phosphorus Radioisotopes; Phosphotransferases; Rats; RNA; Tritium; Uracil Nucleotides; Uridine | 1973 |
[Relation of RNA and protein synthesis in the brain to the state of the cholino- and adrenoreceptors].
Topics: Adenine; Amphetamine; Animals; Arecoline; Benactyzine; Brain; Carbon Radioisotopes; Female; Glycine; Haloperidol; Nerve Tissue Proteins; Orotic Acid; Rats; Receptors, Drug; RNA; Tritium; Uridine | 1974 |
The inhibition of rat liver nuclear ribonucleic acid synthesis by galactosamine and its reversal by uridine.
Topics: Adenine; Animals; Cell Nucleus; Chromatography, Gel; Depression, Chemical; DNA; Dose-Response Relationship, Drug; Female; Galactosamine; In Vitro Techniques; Liver; Orotic Acid; Rats; RNA; Solubility; Stimulation, Chemical; Time Factors; Tritium; Uracil Nucleotides; Uridine | 1974 |
A screening test for urinary purines and pyrimidines and related compounds using auxotrophic mutants of Escherichia coli K12.
Topics: Adenine; Alanine; Aspartic Acid; Biological Assay; Carbamates; Child; Chromatography, Paper; Cytosine; Escherichia coli; Glycosides; Humans; Imidazoles; Inosine; Mutation; Orotic Acid; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Purinones; Pyrimidines; Ribose; Thymine; Uracil; Uric Acid | 1970 |
Effects of hepatocarcinogens on the synthesis and content of rat liver nuclear RNA.
Topics: Adenine; Amides; Animals; Carbon Isotopes; Carcinogens; Cell Nucleus; Female; Liver; Orotic Acid; p-Dimethylaminoazobenzene; Precancerous Conditions; Rats; RNA; Sulfhydryl Compounds | 1968 |
DNA, RNA , and protein synthesis in erythrocytic forms of Plasmodium knowlesi.
Topics: Adenine; Animals; Antimalarials; Carbon Isotopes; Culture Media; DNA; Erythrocytes; Glycine; Haplorhini; Isoleucine; Methionine; Orotic Acid; Phenylalanine; Plasmodium; Protein Biosynthesis; RNA; Sulfur Isotopes; Thymidine; Tritium; Tryptophan; Uracil; Uridine | 1968 |
Interference of barbiturates with pyrimidine incorporation. 3. Studies on the mechanism of the amobarbital-orotate relationship.
Topics: Adenine; Alcohols; Amobarbital; Animals; Arsenic; Azides; Bacillus cereus; Bacillus megaterium; Bacillus subtilis; Biological Transport; Carbon Isotopes; Cell Membrane; Chlorpromazine; Chromatography, Paper; Cyanides; Dinitrophenols; Drug Synergism; Inulin; Kinetics; Mice; Nucleic Acids; Orotic Acid; Oxygen Consumption; Pentobarbital; Potassium; Potassium Isotopes; Pyrimidines; Radioisotopes; Rubidium; Species Specificity; Sucrose; Temperature; Uracil | 1970 |
Effect of chlorpromazine on cell wall biosynthesis and incorporation of orotic acid into nucleic acids in Bacillus megaterium.
Topics: Adenine; Bacillus megaterium; Bacterial Proteins; Carbon Isotopes; Cell Wall; Chlorpromazine; DNA, Bacterial; Formates; Lysine; Models, Biological; Nucleic Acids; Orotic Acid; Pimelic Acids; Promazine; RNA; RNA, Bacterial; Sulfoxides; Thymidine; Time Factors; Trifluoperazine; Uridine | 1971 |
[Problem of active therapeutic procedure in chronic liver disease].
Topics: Adenine; Adult; Aged; Chronic Disease; Diet Therapy; Female; Humans; Inositol; Liver Diseases; Male; Middle Aged; Orotic Acid; Xanthines | 1972 |
Malaria parasites (Plasmodium lophurae) developing extracellularly in vitro: incorporation of labeled precursors.
Topics: Adenine; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Birds; Carbon Isotopes; Cell Nucleus; Choline; Coenzyme A; Culture Media; Erythrocytes; Germ-Free Life; Methionine; Methods; Orotic Acid; Plasmodium; Proline; Pyruvates; Time Factors; Tissue Extracts | 1971 |
Incorporation of precursors into Toxoplasma DNA.
Topics: Adenine; Animals; Carbon Isotopes; Cytidine; DNA; Guanine; Hot Temperature; Mice; Mice, Inbred Strains; Nucleic Acid Denaturation; Nucleotides; Orotic Acid; Purines; Pyrimidines; Thymidine; Time Factors; Toxoplasma; Tritium | 1971 |
Synthetic mechanisms in the axon. IV. In vitro incorporation of [3H]precursors into axonal protein and RNA.
Topics: Adenine; Animals; Axons; Chloramphenicol; Dactinomycin; In Vitro Techniques; Leucine; Microscopy, Phase-Contrast; Nerve Tissue Proteins; Orotic Acid; Photomicrography; Rabbits; Ribonucleases; RNA; Spinal Nerves; Tritium | 1967 |
Pyrimidine and purine bases and nucleosides in wheat plants.
Topics: Adenine; Carbon Isotopes; Chromatography; Cytosine; Nucleosides; Orotic Acid; Purines; Pyrimidines; Radioisotope Dilution Technique; Triticum; Uracil; Uridine | 1967 |
On relationships between induction of liver cancer with azo dyes and changes in nuclear RNA metabolism during carcinogenesis.
Topics: Adenine; Animals; Azo Compounds; Carbon Isotopes; Cell Nucleus; Diet; Female; Liver; Liver Neoplasms; Orotic Acid; Rats; RNA | 1969 |
Effects of urecholine and atropine on canine pancreas slices. On incorporation of 14C-adenine and 14C-orotic acid into acid-soluble metabolites and RNA.
Topics: Adenine; Adenine Nucleotides; Adenosine Triphosphate; Animals; Atropine; Bethanechol Compounds; Carbon Isotopes; Cell Nucleus; Centrifugation, Density Gradient; Choline; Chromatography, Thin Layer; Cytoplasm; Depression, Chemical; Dogs; Hydrogen-Ion Concentration; Hypoxanthines; In Vitro Techniques; Nucleotides; Orotic Acid; Pancreas; RNA; Secretin; Spectrophotometry; Time Factors; Ultraviolet Rays | 1969 |
Biosynthesis de novo of purines and pyrimidines in Mesocestoides (Cestoda). I.
Topics: Adenine; Carbon Isotopes; Cestoda; Chromatography, Thin Layer; Glycine; Isoleucine; Nucleic Acids; Orotic Acid; Purines; Pyrimidines; Uracil | 1970 |
Studies on beta-D-xylofuranosyl-6-thioguanine in mice.
Topics: Adenine; Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cell Line; Chromatography; DNA, Neoplasm; Female; Furans; Glycine; Guanine; Immunosuppressive Agents; Male; Mice; Neoplasms, Experimental; Orotic Acid; Protein Biosynthesis; Purines; Pyrimidines; RNA, Neoplasm; Sulfur Isotopes; Thioguanine; Xylose | 1970 |
Effect of dietary purine restriction, allupurinol, and oxipurinol on urinary excretion of ultraviolet-absorbing compounds.
Topics: Adenine; Allopurinol; Chromatography, Ion Exchange; Diet; Humans; Hypoxanthines; Orotic Acid; Purines; Pyrimidines; Spectrophotometry; Ultraviolet Rays; Uric Acid; Uridine; Xanthine Oxidase | 1970 |
[Biochemical mechanisms of steatosis as sequelae of "nucleotide imbalance"].
Topics: Acetates; Adenine; Adenine Nucleotides; Adenosine Triphosphate; Animals; Azaserine; Biotin; Carbon Isotopes; Cholesterol; Disease Models, Animal; Ethionine; Fatty Liver; Lipid Metabolism; Lipids; Nucleotides; Orotic Acid; Phospholipids; Pyrazoles; Pyrimidines; Rats; Triglycerides | 1970 |
Studies on the coordinate activity and liability of orotidylate phosphoribosyltransferase and decarboxylase in human erythrocytes, and the effects of allopurinol administration.
Topics: Adenine; Allopurinol; Carbon Isotopes; Carboxy-Lyases; Centrifugation, Density Gradient; Depression, Chemical; Erythrocytes; Humans; Hypoxanthines; Lesch-Nyhan Syndrome; Nucleosides; Orotic Acid; Transferases; Uracil Nucleotides | 1971 |
Biosynthesis of the formycin family.
Topics: Adenine; Adenine Nucleotides; Anti-Bacterial Agents; Aspartic Acid; Carbon Isotopes; Formates; Glutamates; Glycine; Nocardia; Orotic Acid; Ribose; RNA, Bacterial; Serine; Uracil | 1971 |
Behaviour of lipoperoxidation in rat liver during orotic acid treatment.
Topics: Adenine; Aldehydes; Animals; Arachidonic Acids; Cytoplasm; In Vitro Techniques; Lipid Metabolism; Lipids; Liver; Malonates; Microsomes, Liver; Mitochondria, Liver; Orotic Acid; Oxidation-Reduction; Peroxides; Phospholipids; Rats; Spectrophotometry; Ultraviolet Rays | 1971 |
Regulatory effect of N6-benzyladenine and pseudothymine (6-methyluracyl) on the synthesis of nucleic acids.
Topics: Adenine; Carbon Isotopes; Orotic Acid; Plants; Purines; Pyrimidines; RNA; Thymine; Uracil | 1968 |
Nucleotide metabolism in rat brain.
Topics: Adenine; Animals; Aspartic Acid; Carbon Isotopes; Cerebral Cortex; Chromatography, Paper; DNA; Glucosyltransferases; Glycine; Guanine; Hypoxanthines; In Vitro Techniques; Nerve Tissue Proteins; Nucleosides; Nucleotides; Orotic Acid; Oxidoreductases; Phosphotransferases; Rats; RNA; Uridine; Xanthine Oxidase; Xanthines | 1968 |
Effect of denervation on the synthesis of ribonucleic acid and deoxyribonucleic acid in rat diaphragm muscle.
Topics: Adenine; Animals; Carbon Isotopes; Diaphragm; DNA; DNA Replication; Hypertrophy; Muscle Denervation; Muscles; Orotic Acid; Rats; RNA; Thymidine; Time Factors; Tritium | 1968 |
The rapid acceleration of hepatic nuclear ribonucleic acid breakdown by actinomycin but not by ethionine.
Topics: Adenine; Animals; Carbon Isotopes; Dactinomycin; Ethionine; Liver; Methionine; Orotic Acid; Rats; RNA | 1968 |
3 nuclear RNA fractions and their relationship to polysomal mRNA.
Topics: Adenine; Animals; Cell Nucleus; Cytosine; Guanine; Hybridization, Genetic; Liver; Liver Extracts; Orotic Acid; Phosphorus Isotopes; Rats; Ribosomes; RNA; RNA, Messenger; Tritium; Uracil | 1968 |
Protection by orotic acid against the renal necrosis and fatty liver of choline deficiency.
Topics: Adenine; Animals; Choline Deficiency; Fatty Liver; Hemorrhage; Kidney; Liver; Male; Necrosis; Orotic Acid; Rats; Triglycerides | 1968 |
Metabolic effects of azaserine in rat brain.
Topics: Adenine; Animals; Azaserine; Brain; Carbon Isotopes; Centrifugation; Chromatography, Ion Exchange; Chromatography, Paper; Female; Glycine; Lysine; Nerve Tissue Proteins; Nucleotides; Orotic Acid; Paraplegia; Phenylalanine; Purines; Pyrimidines; Rats; RNA; Spectrum Analysis; Tritium | 1969 |
Isolation and characterization of low density structures from orotic acid-induced fatty livers.
Topics: Adenine; Animals; Carbon Isotopes; Centrifugation, Density Gradient; Endoplasmic Reticulum; Fatty Liver; Female; Lipids; Liver; Microscopy, Electron; Microsomes; Nucleotides; Orotic Acid; Proteins; Rats; Ribosomes; RNA | 1969 |
The control of RNA synthesis during liver regeneration. OMP pyrophosphorylase and decarboxylase activities in normal and regenerating liver.
Topics: Adenine; Animals; Carbon Isotopes; Carboxy-Lyases; Genetics; Hepatectomy; Liver; Liver Regeneration; Magnesium; Male; Microsomes; Nucleotides; Orotic Acid; Pentosephosphates; Rats; RNA; Time Factors; Transferases; Uracil Nucleotides | 1969 |
Hepatic ATP and triglyceride levels in choline-deficient rats with and without dietary orotic acid supplementation.
Topics: Adenine; Adenosine Triphosphate; Animals; Choline Deficiency; Diet; Dietary Fats; Fatty Liver; Liver; Male; Orotic Acid; Rats; Sulfates; Triglycerides | 1969 |
Effect of dietary orotic acid and adenine sulfate on hepatic microsomal enzymes in male and female rats.
Topics: Adenine; Aniline Compounds; Animals; Cytochromes; Diet; Female; Formaldehyde; Liver; Male; Microsomes; Mixed Function Oxygenases; Morphinans; Orotic Acid; Oxidoreductases; Phenols; Rats; Sex Factors; Uracil Nucleotides | 1969 |
Metabolic aspects of "orotic acid fatty liver". Nucleotide control mechanisms of lipid metabolism.
Topics: Adenine; Aminohydrolases; Animals; DNA; Fatty Liver; Lipid Metabolism; Nucleotides; Orotic Acid; Phospholipids; Rats; RNA; Transferases; Xanthine Oxidase | 1964 |
Studies on the nuclear and nucleolar ribonucleic acid of regenerating rat liver.
Topics: Adenine; Animals; Cell Nucleolus; Cell Nucleus; Chemistry Techniques, Analytical; Cytosine; Guanine; Hepatectomy; In Vitro Techniques; Liver; Liver Regeneration; Orotic Acid; Phosphates; Rats; RNA; Ultracentrifugation; Uracil | 1965 |
Stimulation of hepatic purine biosynthesis by orotic acid.
Topics: Adenine; Animals; Chromatography, Paper; Feedback; Formates; Glycine; Hippurates; In Vitro Techniques; Liver; Orotic Acid; Purines; Rats | 1965 |
The inhibition of liver ribonucleic acid synthesis by ethionine.
Topics: Adenine; Adenosine Triphosphate; Animals; Cell Nucleus; Ethionine; In Vitro Techniques; Liver; Methionine; Microsomes; Orotic Acid; Rats; RNA | 1966 |
The role of deoxyribose 5-phosphate aldolase in the synthesis of deoxyribonucleotide in mammalian cells.
Topics: Adenine; Aldehyde-Lyases; Animals; Aspartic Acid; Carcinoma, Ehrlich Tumor; Deoxyuridine; DNA; Glycine; In Vitro Techniques; Liver; Liver Regeneration; Mice; Nucleotides; Orotic Acid; Protein Biosynthesis; Rats; RNA; Subcellular Fractions; Threonine; Thymidine; Uridine | 1966 |
The relationship between cellular nucleic acids in the developing rat cerebral cortex.
Topics: Adenine; Animals; Animals, Newborn; Brain Chemistry; Cell Nucleus; Cerebral Cortex; Cytosine; DNA; Guanine; In Vitro Techniques; Microsomes; Orotic Acid; Rats; Ribosomes; RNA; Subcellular Fractions; Uracil | 1966 |
Studies on the biochemical mode of action of a cytotoxic methylhydrazine derivative, N-isopropyl-alpha-(2-methylhydrazino)-p-toluamide.
Topics: Adenine; Amines; Animals; Antineoplastic Agents; Carbon Isotopes; DNA; Formates; Guanine; Hydrazines; Imidazoles; Leucine; Lymphoma; Male; Mice; Neoplasms, Experimental; Nucleosides; Nucleotides; Orotic Acid; Protein Biosynthesis; Purines; RNA; Thymidine; Thymidine Kinase; Tritium | 1966 |
[Effects and side-effects of orotic acid].
Topics: Adenine; Animals; Drug Synergism; Fatty Liver; Galactosemias; Nucleotides; Orotic Acid; Purines; Rats | 1966 |
Metabolically stable and metabolically labile DNA-like RNA.
Topics: Adenine; Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cell Nucleus; Cytosine; DNA; DNA, Neoplasm; Guanine; In Vitro Techniques; Liver; Mice; Orotic Acid; RNA; RNA, Neoplasm; Ultracentrifugation; Uracil | 1967 |
Counter-current distribution of rapidly labelled RNA from rats treated with hormones.
Topics: Adenine; Animals; Carbon Isotopes; Countercurrent Distribution; Hydrocortisone; In Vitro Techniques; Insulin; Liver; Orotic Acid; Rats; RNA; Thyroxine; Tritium | 1967 |
[Orotic acid and hepatic regeneration after partial hepatectomy in the rat].
Topics: Adenine; Animals; Dietary Carbohydrates; Dietary Proteins; Hepatectomy; Lipids; Liver; Liver Regeneration; Orotic Acid; Rats; Sulfates | 1967 |
Re-evaluation of the effect of insulin on nucleic acid synthesis in muscle.
Topics: Adenine; Animals; Carbon Isotopes; Diaphragm; Insulin; Muscles; Orotic Acid; Rats; RNA; Uracil | 1967 |
Biosynthesis of RNA in slices of guinea pig cerebral cortex.
Topics: Adenine; Animals; Carbon Isotopes; Cerebral Cortex; Chromatography, Thin Layer; Dactinomycin; Electrophoresis; Guinea Pigs; In Vitro Techniques; Orotic Acid; Paper; Phosphorus Isotopes; RNA; Tritium; Uracil; Uracil Nucleotides; Uridine | 1967 |
Poly(A)-containing RNA in the livers of ethionine-treated rats.
Topics: Adenine; Animals; Ethionine; Fasting; Female; Liver; Orotic Acid; Poly A; Rats; RNA; Time Factors | 1980 |
Phosphoribosylpyrophosphate bioavailability in diabetic rat renal cortex in vivo.
Topics: Adenine; Adenosine Triphosphate; Animals; Biological Availability; Diabetes Mellitus, Experimental; Infusions, Parenteral; Kidney Cortex; Male; Orotic Acid; Pentosephosphates; Phosphoribosyl Pyrophosphate; Rats; RNA; Uridine Triphosphate | 1980 |
Alterations in glomerular RNA in diabetic rats: roles of glucagon and insulin.
Topics: Adenine; Animals; Biotransformation; Diabetes Mellitus, Experimental; Glucagon; Glucose; Insulin; Kidney Glomerulus; Male; Orotic Acid; Rats; RNA; Streptozocin | 1981 |
Influence of dietary purines on allopurinol metabolism and allopurinol induced oroticaciduria.
Topics: Adenine; Adenosine; Allopurinol; Diet; Humans; Hypoxanthine; Hypoxanthines; Male; Orotic Acid; Purines | 1984 |
Fatty liver of growing rats fed excess lysine and its prevention by adenine or allopurinol.
Topics: Adenine; Allopurinol; Animals; Arginine; Diet; Fatty Liver; Lipid Metabolism; Liver; Lysine; Male; Orotic Acid; Rats | 1981 |
Reduction of beta-oxidation capacity of rat liver mitochondria by feeding orotic acid.
Topics: Acyl-CoA Dehydrogenases; Adenine; Animals; Clofibric Acid; Diet; Fatty Acids; Fatty Liver; Male; Mitochondria, Liver; Orotic Acid; Oxidation-Reduction; Pantetheine; Rats; Rats, Inbred Strains | 1982 |
Effect of some dietary additions to either an arginine-devoid diet or a diet supplemented with orotic acid refed after starvation on liver lipid content during essential fatty acid deficiency in rats.
Topics: Adenine; Allopurinol; Animals; Arginine; Diet; Fatty Acids, Essential; Food; Lipid Metabolism; Liver; Male; Orotic Acid; Rats; Starvation | 1981 |
[DNA methylation in wheat seedling and influence of phytohormones].
Topics: Adenine; Benzyl Compounds; Carbon Radioisotopes; Cytosine; DNA; Indoleacetic Acids; Kinetin; Methylation; Orotic Acid; Phenylacetates; Plant Growth Regulators; Plants; Purines; Triticum | 1981 |
De novo synthesis of purine nucleotides in human blood platelets.
Topics: Adenine; Allopurinol; Azaserine; Blood Platelets; Formates; Humans; Hypoxanthines; Orotic Acid; Phosphoribosyl Pyrophosphate; Purine Nucleotides | 1980 |
Telomere-associated chromosome breakage in fission yeast results in variegated expression of adjacent genes.
Topics: Adenine; Cell Division; Chromosome Aberrations; DNA, Recombinant; Electrophoresis, Gel, Pulsed-Field; Extrachromosomal Inheritance; Gene Expression Regulation, Fungal; Gene Rearrangement; Genes, Fungal; Leucine; Orotic Acid; RNA, Fungal; Schizosaccharomyces; Uracil | 1994 |
Effect of orotic acid on in vivo DNA synthesis in hepatocytes of normal rat liver and in hepatic foci/nodules.
Topics: Adenine; Animals; Diethylnitrosamine; DNA; DNA Replication; gamma-Glutamyltransferase; Glutathione Transferase; Hepatectomy; Kinetics; Liver; Liver Regeneration; Male; Orotic Acid; Rats; Rats, Inbred F344; Time Factors | 1993 |
Metabolic effect of orotic acid in rat L6 myoblasts.
Topics: Adenine; Adenosylmethionine Decarboxylase; Animals; Bucladesine; Cell Division; Cell Line; Culture Media; DNA; Fetal Blood; Muscle Proteins; Muscles; Ornithine Decarboxylase; Orotic Acid; Putrescine; Rats; Spermine | 1993 |
The effects of various inhibitors on the regulation of orotic acid excretion in sparse-fur mutant mice (spf/Y) deficient in ornithine transcarbamylase.
Topics: Adenine; Animals; Antimetabolites; Aspartic Acid; Creatinine; Cycloheximide; Injections, Intraperitoneal; Isoxazoles; Liver; Male; Mice; Mice, Mutant Strains; Ornithine; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Phosphonoacetic Acid | 1993 |
Effect of orotic acid on beta 1,4-galactosyltransferase during liver regeneration.
Topics: Adenine; Animals; Galactosyltransferases; Hepatectomy; Kinetics; Liver Regeneration; Male; Orotic Acid; Rats; Rats, Inbred F344; RNA, Messenger | 1993 |
Automated screening system for purine and pyrimidine metabolism disorders using high-performance liquid chromatography.
Topics: Adenine; Adenosine; Autoanalysis; Chromatography, High Pressure Liquid; Humans; Orotic Acid; Pseudouridine; Purine-Pyrimidine Metabolism, Inborn Errors; Uracil; Xanthine; Xanthines | 1995 |
Antagonistic effect of nucleic acid precursors on the anticoccidial activity of 6-azauracil.
Topics: Adenine; Adenosine; Animals; Chickens; Coccidiosis; Coccidiostats; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance; Eimeria; Food, Fortified; Male; Nucleic Acid Precursors; Orotic Acid; Poultry Diseases; Uracil; Uridine | 1996 |
Media formulations for various two-hybrid systems.
Topics: Adenine; Carbon; Culture Media; Cycloheximide; Fungal Proteins; Genes, Reporter; Genetic Techniques; Genetic Vectors; Mycology; Orotic Acid; Protein Processing, Post-Translational; RNA, Fungal; Saccharomyces cerevisiae; Two-Hybrid System Techniques | 2001 |
[Treatment of diseases of liver parenchyma; experiences with intravenous injections of a preparation containing a mixture of orotic acid and purines].
Topics: Adenine; Humans; Injections, Intravenous; Liver Diseases; Orotic Acid; Purines; Xanthines | 1956 |
Studies of the mechanism of action of urethane in initiating pulmonary adenomas in mice. II. Its relation to nucleic acid synthesis.
Topics: Adenine; Adenoma; Animals; DNA; Lung Neoplasms; Mice; Neoplasms; Nucleic Acids; Orotic Acid; Pyrimidines; RNA; Thymine; Urethane | 1957 |
[Effects of a new preparation of purinic and orotic acid base in chronic liver diseases].
Topics: Adenine; Alkalies; Humans; Liver Diseases; Organic Chemicals; Orotic Acid; Xanthines | 1957 |
Incorporation of adenine-8-C-14 and orotic-6-C-14 acid into nucleic acids of the feline neuraxis.
Topics: Adenine; Animals; Cats; Central Nervous System; Nervous System; Nucleic Acids; Orotic Acid | 1958 |
Uptake of adenine-8-C14 and orotic-6-C14 acid into nuclear DNA of non-dividing cells in the adult feline neuraxis.
Topics: Adenine; Animals; Biochemical Phenomena; Cats; Central Nervous System; DNA; Nervous System; Orotic Acid | 1958 |
[Experimental studies with liver-effective substances].
Topics: Adenine; Liver; Orotic Acid; Xanthines | 1958 |
The effect of deoxyribonuclease on the incorporation of precursors into nuclear ribonucleic acid in reconstituted rat-liver homogenates.
Topics: Adenine; Animals; Deoxyribonucleases; DNA; Liver; Orotic Acid; Rats; RNA | 1962 |
[Study of the reconstitution of nucleotides and ribonucleic acid in the crystalline lens].
Topics: Adenine; Glycine; Lens, Crystalline; Nucleotides; Orotic Acid; RNA | 1963 |
Depression of plasma lipids in the rat by orotic acid and its reversal by adenine.
Topics: Adenine; Animals; Depression; Lipids; Orotic Acid; Rats | 1963 |
INHIBITORY ACTION OF ADENINE, ADENINENUCLEOSIDES AND NUCLEOTIDES ON THE BIOSYNTHESIS OF PORPHYRINS BY RHODOPSEUDOMONASSPHEROIDES.
Topics: Adenine; Adenine Nucleotides; Adenosine Triphosphate; Antimetabolites; Chlorophyll; Levulinic Acids; Metabolism; Nucleosides; Nucleotides; Orotic Acid; Pharmacology; Porphyrins; Research; Rhodopseudomonas; Thymine; Uracil | 1963 |
CHEMICAL REACTIVITY OF THE NUCLEIC ACID BASES. I. ANTIOXIDATIVE ABILITY OF THE NUCLEIC ACIDS AND THEIR RELATED SUBSTANCES ON THE OXIDATION OF UNSATURATED FATTY ACIDS.
Topics: Adenine; Antioxidants; Catechols; Citrates; Copper; Diphosphates; Fats, Unsaturated; Fatty Acids, Unsaturated; Linoleic Acid; Lipid Metabolism; Nucleic Acids; Nucleosides; Orotic Acid; Oxidation-Reduction; Research; RNA; Uracil; Uric Acid; Vitamin E; Xanthines | 1963 |
[INHIBITORY ACTION OF NUCLEOSIDES AND ADENINE NUCLEOTIDES ON THE BIOSYNTHESIS OF PORPHYRINS BY RHODOPSEUDOMONAS SPHEROUIDES].
Topics: Adenine; Adenine Nucleotides; Adenosine Triphosphate; Antimetabolites; Glycine; Ketoglutaric Acids; Levulinic Acids; Nucleosides; Orotic Acid; Pharmacology; Porphyrins; Research; Rhodopseudomonas; Succinates; Thymidine; Thymine; Uracil | 1963 |
[ON THE EXISTENCE OF RAPIDLY LABELED DESOXYRIBONUCLEIC FRACTION IN ANIMAL CELLS].
Topics: Adenine; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; DNA; Liver; Liver Neoplasms; Neoplasm Proteins; Neoplasms, Experimental; Orotic Acid; Radiometry; Research; Thymidine; Tritium | 1964 |
PURINE METABOLISM OF UNICELLULAR ALGAE. I. CHROMATOGRAPHIC DETECTION OF SOME PURINES, PYRIMIDINES, AND IMIDAZOLES BY THEIR MERCURIC COMPLEXES.
Topics: Adenine; Alloxan; Chromatography; Creatine; Creatinine; Eukaryota; Guanine; Hydantoins; Hypoxanthines; Imidazoles; Mercury; Orotic Acid; Purines; Pyrimidines; Research; Ultraviolet Rays; Uric Acid; Xanthines | 1964 |
INHIBITION OF DNA SYNTHESIS IN MAMMALIAN CELLS BY ACTIDIONE.
Topics: Adenine; Adenine Nucleotides; Anti-Bacterial Agents; Aspartic Acid; Carbon Isotopes; Carcinoma, Squamous Cell; Cycloheximide; Cytosine Nucleotides; DNA; DNA Replication; DNA, Neoplasm; Formates; Glycine; Guanine Nucleotides; Leucine; Metabolism; Neoplasms; Nucleosides; Nucleotides; Nucleotidyltransferases; Orotic Acid; Pharmacology; Research; RNA; RNA, Neoplasm; Thymidine; Tissue Culture Techniques; Tritium | 1964 |
AN OROTIC ACID-INDUCED, ADENINE-REVEREED INHIBITION OF HEPATIC LIPOPROTEIN SECRETION IN THE RAT.
Topics: Adenine; Adipose Tissue; Antimetabolites; Cholesterol; Fatty Acids; Fatty Liver; Glycerides; Intestines; Lipid Metabolism; Lipoproteins; Liver; Mesentery; Orotic Acid; Pharmacology; Phospholipids; Rats; Research; Surface-Active Agents; Tritium | 1964 |
FORMATION OF RIBOMONONUCLEOTIDES FROM PURINE AND PYRIMIDINE BASES AND 5'-PHOSPHORIBOSYLPYROPHOSPHATE BY A SALMON MILT EXTRACT.
Topics: Adenine; Adenine Nucleotides; Animals; Carbon Isotopes; Chromatography; Cytosine; Cytosine Nucleotides; Diphosphates; Fishes; Guanine; Guanine Nucleotides; Metabolism; Nucleotides; Orotic Acid; Phosphoribosyl Pyrophosphate; Purines; Pyrimidines; Research; Salmon; Thymine; Tissue Extracts; Tritium; Uracil; Uracil Nucleotides; Xanthines | 1964 |
URACIL METABOLISM IN TADPOLES DURING THYROXINE-INDUCED METAMORPHOSIS.
Topics: Adenine; Animals; Anura; Carbamates; Cytosine; Glucosyltransferases; Larva; Ligases; Liver; Metabolism; Metamorphosis, Biological; Nucleosides; Orotic Acid; Pharmacology; Phosphates; Ranidae; Research; Thyroxine; Uracil | 1964 |
PERIPORTAL FATTY LIVER IN THE RAT INDUCED BY HIGH PROTEIN OROTIC ACID DIETS.
Topics: Adenine; Diet; Dietary Proteins; Fatty Liver; Orotic Acid; Pharmacology; Rats; Research; Toxicology | 1964 |
[STUDY OF THE PASSAGE OF CERTAIN PRECURSORS OF NUCLEIC ACIDS FROM THE CEREBROSPINAL FLUID INTO THE CENTRAL NERVOUS SYSTEM].
Topics: Adenine; Blood; Blood-Brain Barrier; Carbon Isotopes; Guanine; Nucleic Acids; Nucleosides; Nucleotides; Orotic Acid; Physiology; Radiometry; Rats; Research; Uracil; Uridine | 1964 |
HEPATIC NUCLEOTIDE LEVELS AND NAD-SYNTHESIS AS INFLUENCED BY DIETARY OROTIC ACID AND ADENINE.
Topics: Adenine; Adenine Nucleotides; Diet; Guanine Nucleotides; Lipids; Liver; Metabolism; NAD; Niacin; Niacinamide; Nicotinic Acids; Nucleotides; Orotic Acid; Rats; Research; Spectrum Analysis; Uracil Nucleotides | 1965 |
EFFECTS OF THIOACETAMIDE ON NUCLEAR AND NUCLEOLAR RNA OF THE RAT LIVER.
Topics: Adenine; Amides; Anesthetics, Local; Carbon Isotopes; Cell Nucleolus; Cell Nucleus; Cytosine; Guanine; Liver; Metabolism; Orotic Acid; Rats; Research; RNA; Sulfhydryl Compounds; Thioacetamide; Uracil | 1965 |
THE EFFECTS OF 3'-DEOXYADENOSINE ON THE SYNTHESIS OF RIBONUCLEIC ACID.
Topics: Adenine; Adenosine Triphosphate; Antimetabolites; Antineoplastic Agents; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cytosine Nucleotides; Deoxyadenosines; Formates; Glycine; Guanine; Metabolism; Mice; Neoplasms; Nucleosides; Nucleotidyltransferases; Orotic Acid; Pharmacology; Polynucleotides; Research; RNA; RNA, Neoplasm; Tissue Culture Techniques; Uracil Nucleotides; Xanthines | 1965 |
METABOLIC EFFECTS OF AN ANTIBIOTIC, NSC-51954, ON SUSCEPTIBLE AND RESISTANT TUMOR CELLS.
Topics: Adenine; Animals; Anti-Bacterial Agents; Carbon Isotopes; Carcinoma, Ehrlich Tumor; DNA; DNA, Neoplasm; Guanine; Guanine Nucleotides; Leukemia; Leukemia, Experimental; Mice; Neoplasm Proteins; Neoplasms; Orotic Acid; Pharmacology; Phosphotransferases; Proteins; Radiometry; Research; RNA; RNA, Neoplasm; Sarcoma 180; Toxicology; Uracil | 1965 |
EFFECT OF AZASERINE ON THE INCORPORATION OF 14-C-LABELED PURINES AND PYRIMIDINES INTO ACID-SOLUBLE AND NUCLEIC ACID FRACTIONS OF TRYPANOSOMA EQUIPERDUM.
Topics: Adenine; Amino Acids; Azaserine; Cytosine; Cytosine Nucleotides; DNA; Glutamine; Guanine; Hypoxanthines; Leucine; Metabolism; Nucleic Acids; Orotic Acid; Pharmacology; Purines; Pyrimidines; Research; RNA; Thymine; Trypanosoma; Tryptophan; Tyrosine; Uracil; Uracil Nucleotides | 1965 |
METABOLISM OF TISSUE CELLS IN SUSPENSION. SYNTHESIS OF RIBONUCLEIC ACID BY LEIVER CELLS IN SUSPENSION.
Topics: Adenine; Liver; Metabolism; Orotic Acid; Phosphates; Rats; Research; RNA; Uracil | 1965 |