adenine and o-(6)-methylguanine

adenine has been researched along with o-(6)-methylguanine in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199015 (48.39)18.7374
1990's9 (29.03)18.2507
2000's5 (16.13)29.6817
2010's2 (6.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, ST; Choong, KF; Hsieh, JF; Wu, SH; Yang, YL1
Ahnström, G; Eizirik, DL; Sandler, S; Welsh, M1
Kamiya, H; Miura, K; Nishimura, S; Ohtomo, N; Ohtsuka, E1
Abbondandolo, A; Bonatti, S; Cercignani, G; Rocco, M1
Poltev, VI; Steinberg, SV1
Murray, V1
Linn, S; Samson, L1
Colaço, CB; Harris, G; Irving, W; Lawley, PD; Lydyard, PM; Phillips, E; Roitt, IM1
Briscoe, WT; Cotter, LE1
Bresil, H; Cooper, DP; Margison, GP; Montesano, R; O'Connor, PJ; Planche-Martel, G; Smith, RA1
Chu, YH; Craig, AW; O'Connor, PJ1
Aurich, O; Heindorff, K; Kaina, B1
Sklar, RM; Strauss, BS1
Alekandrov, VA; Anisimov, VN; Bespalov, VG; Korsakov, MV; Likhachev, AJ; Napalkov, NP; Ovsyannikov, AI; Popovich, IG; Tomatis, L1
Barrows, LR; Magee, PN1
Kerler, R; Rabes, HM; Rode, G; Wilhelm, R1
Abanobi, SE; Columbano, A; Mulivor, RA; Rajalakshmi, S; Sarma, DS1
Abbondandolo, A; Aprile, A; Arena, G; Bonatti, S; Cavalieri, Z; Pellerano, P; Rocco, M; Sailer, K; Viaggi, S1
Berman, HM; Gaffney, B; Ginell, SL; Jones, R; Vojtechovsky, J1
Aquilina, G; Bignami, M; Biondo, R; Dogliotti, E1
Dunman, PM; Humayun, MZ; Murphy, HS; Rahman, MS; Wang, G1
Augusto, O; Hix, S1
Karran, P; Macpherson, P; O'Driscoll, M; Xu, YZ1
Osheroff, N; Sabourin, M1
Abbondandolo, A; Bonatti, S; Pigullo, S; Simili, M1
Brennand, J; Fox, M1
Chadt, J; Nilsson, R; Sykora, D; Vodicka, P1
Amegayibor, FS; Lee, JK; Liu, M; Sun, X; Zhachkina, A1
Lawley, PD; Warren, W1
Chao, MR; Chen, JL; Hu, CW; Lee, H; Li, YJ1
Belousova, EA; Boldinova, EO; Lavrik, OI; Makarova, AV1

Reviews

1 review(s) available for adenine and o-(6)-methylguanine

ArticleYear
Enhanced repair of O6-alkylguanine in mammalian tissues.
    Folia biologica, 1984, Volume: 30 Spec No

    Topics: 2-Acetylaminofluorene; Adenine; Aflatoxin B1; Aflatoxins; Alkylating Agents; Alkylation; Animals; Carcinogens; Cricetinae; Dimethylnitrosamine; DNA; DNA Repair; Dose-Response Relationship, Drug; Gerbillinae; Guanine; Hepatectomy; Liver; Methylnitrosourea; Mice; Rats; Rodentia; Species Specificity

1984

Other Studies

30 other study(ies) available for adenine and o-(6)-methylguanine

ArticleYear
The screening and characterization of 6-aminopurine-based xanthine oxidase inhibitors.
    Bioorganic & medicinal chemistry, 2007, May-15, Volume: 15, Issue:10

    Topics: Allopurinol; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; Enzyme Inhibitors; Kinetics; Magnetic Resonance Spectroscopy; Mass Spectrometry; Plant Leaves; Purines; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Triticum; Xanthine Oxidase

2007
Exposure of pancreatic islets to different alkylating agents decreases mitochondrial DNA content but only streptozotocin induces long-lasting functional impairment of B-cells.
    Biochemical pharmacology, 1991, Nov-27, Volume: 42, Issue:12

    Topics: Adenine; Alkylating Agents; Animals; Cytochrome b Group; DNA; Dose-Response Relationship, Drug; Glucagon; Glucose; Guanine; Immunoblotting; Insulin; Islets of Langerhans; Male; Methyl Methanesulfonate; Methylnitrosourea; Mice; Mitochondria; RNA, Messenger; Streptozocin

1991
Transforming activity of a synthetic c-Ha-ras gene containing O6-methylguanine in codon 12.
    Japanese journal of cancer research : Gann, 1991, Volume: 82, Issue:9

    Topics: 3T3 Cells; Adenine; Amino Acid Sequence; Animals; Base Sequence; Cell Transformation, Neoplastic; Codon; Genes, ras; Genes, Synthetic; Genetic Vectors; Guanine; Humans; Mice; Molecular Sequence Data; Mutagenesis, Insertional; Mutation; Oligonucleotides; Transfection

1991
Aneuploidy induction by alkylated bases and nucleosides in mammalian cells.
    Progress in clinical and biological research, 1990, Volume: 340B

    Topics: Adenine; Adenosine Deaminase; Alkylation; Aneuploidy; Animals; Cells, Cultured; Cricetinae; Cricetulus; DNA Damage; Guanine; Guanosine; Humans; Hypoxanthine Phosphoribosyltransferase; Methyltransferases; Models, Biological; Nucleosides; O(6)-Methylguanine-DNA Methyltransferase; Purine-Nucleoside Phosphorylase; Structure-Activity Relationship

1990
The role of structural water in the formation of nucleotide mispairs.
    Journal of biomolecular structure & dynamics, 1987, Volume: 5, Issue:2

    Topics: Adenine; Base Composition; Computer Simulation; Cytosine; DNA Damage; DNA Replication; Guanine; Magnetic Resonance Spectroscopy; Mutation; Nucleic Acid Conformation; Thermodynamics; Uracil; Water

1987
O6-methylguanine specifically induces AT----GC transition mutations.
    Mutation research, 1987, Volume: 190, Issue:4

    Topics: 5-Methylcytosine; Adenine; Alkylation; Base Composition; Cytosine; DNA Damage; DNA, Bacterial; Escherichia coli; Guanine; Hypoxanthine; Hypoxanthines; Mutation

1987
DNA alkylation repair and the induction of cell death and sister chromatid exchange in human cells.
    Carcinogenesis, 1987, Volume: 8, Issue:2

    Topics: Adenine; Alkylating Agents; Alkylation; Cell Survival; DNA Repair; Guanine; HeLa Cells; Humans; Methylnitronitrosoguanidine; Purines; Sister Chromatid Exchange

1987
Repair of chemical carcinogen-induced damage in DNA of human lymphocytes and lymphoid cell lines--studies of the kinetics of removal of O6-methylguanine and 3-methyladenine.
    Chemico-biological interactions, 1986, Volume: 57, Issue:1

    Topics: Adenine; Autoimmune Diseases; Carcinogens; Cell Line; DNA Repair; Guanine; Humans; Kinetics; Lymphocytes; Mathematics; Models, Chemical

1986
DNA sequence has an effect on the extent and kinds of alkylation of DNA by a potent carcinogen.
    Chemico-biological interactions, 1985, Dec-31, Volume: 56, Issue:2-3

    Topics: Adenine; Alkylation; Animals; Base Sequence; Cattle; DNA; Guanine; Methylnitrosourea; Polydeoxyribonucleotides; Structure-Activity Relationship; Thymus Gland; Tritium

1985
Repair of O6-methylguanine in rat liver DNA is enhanced by pretreatment with single or multiple doses of aflatoxin B1.
    British journal of cancer, 1981, Volume: 43, Issue:6

    Topics: Adenine; Aflatoxin B1; Aflatoxins; Animals; Dimethylnitrosamine; DNA Repair; Guanine; Liver; Male; Rats; Stimulation, Chemical

1981
O6-methylguanine, but not N7-methylguanine or N3-methyladenine, induces gene mutations, sister-chromatid exchanges and chromosomal aberrations in Chinese hamster cells.
    Mutation research, 1983, Volume: 108, Issue:1-3

    Topics: Adenine; Animals; Cells, Cultured; Chromosome Aberrations; Cricetinae; Crossing Over, Genetic; Dose-Response Relationship, Drug; Guanine; Karyotyping; Mutation; Sister Chromatid Exchange

1983
O6-Methylguanine removal by competent and incompetent human lymphoblastoid lines from the same male individual.
    Cancer research, 1983, Volume: 43, Issue:7

    Topics: Adenine; Cell Division; Cell Line; Chromosome Aberrations; Guanine; Humans; Karyotyping; Lymphocyte Activation; Lymphocytes; Male; Methylnitronitrosoguanidine

1983
Persistence of methylated purines in the DNA of various rat fetal and maternal tissues and carcinogenesis in the offspring following a single transplacental dose of N-methyl-N-nitrosourea.
    International journal of cancer, 1983, Jun-15, Volume: 31, Issue:6

    Topics: Adenine; Animals; Brain; DNA; Female; Fetus; Guanine; Kidney; Liver; Methylation; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Placenta; Pregnancy; Purines; Rats; Time Factors

1983
Nonenzymatic methylation of DNA by S-adenosylmethionine in vitro.
    Carcinogenesis, 1982, Volume: 3, Issue:3

    Topics: Adenine; Animals; Cattle; Chromatography, High Pressure Liquid; DNA; DNA Repair; Guanine; In Vitro Techniques; Methylation; S-Adenosylmethionine; Scintillation Counting; Spectrophotometry, Ultraviolet

1982
Dose- and cell cycle-dependent O6-methylguanine elimination from DNA in regenerating rat liver after [14C]dimethylnitrosamine injection.
    Cancer research, 1982, Volume: 42, Issue:9

    Topics: Adenine; Animals; Dimethylnitrosamine; DNA; DNA Repair; Dose-Response Relationship, Drug; Guanine; Interphase; Liver; Liver Regeneration; Male; Rats

1982
In vivo replication of hepatic deoxyribonucleic acid of rats treated with dimethylnitrosamine: presence of dimethylnitrosamine-induced O6-methylguanine, N7-methylguanine, and N3-methyladenine in the replicated hybrid deoxyribonucleic acid.
    Biochemistry, 1980, Apr-01, Volume: 19, Issue:7

    Topics: Adenine; Animals; Dimethylnitrosamine; DNA Replication; Guanine; Liver; Male; Nucleic Acid Hybridization; Rats

1980
Induction of kinetochore-containing micronuclei by exogenous O6-methylguanine requires conversion of the methylated base to a nucleotide.
    Environmental and molecular mutagenesis, 1995, Volume: 26, Issue:3

    Topics: Adenine; Animals; Cell Line; Cricetinae; Cricetulus; Guanine; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Kinetochores; Methyl Methanesulfonate; Mice; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagens

1995
Crystal structure of a mispaired dodecamer, d(CGAGAATTC(O6Me)GCG)2, containing a carcinogenic O6-methylguanine.
    Biochemistry, 1994, Mar-29, Volume: 33, Issue:12

    Topics: Adenine; Base Composition; Base Sequence; Carcinogens; Crystallization; Crystallography, X-Ray; Guanine; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Molecular Structure; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Software

1994
Genetic consequences of tolerance to methylation DNA damage in mammalian cells.
    Carcinogenesis, 1993, Volume: 14, Issue:10

    Topics: Adenine; Adenine Phosphoribosyltransferase; Animals; Aza Compounds; Base Sequence; Cell Survival; CHO Cells; Cricetinae; DNA; DNA Damage; Drug Resistance; Guanine; Methylation; Methylnitrosourea; Molecular Sequence Data; Mutation; Ouabain; Thioguanine

1993
Effect of UVM induction on mutation fixation at non-pairing and mispairing DNA lesions.
    Molecular microbiology, 1996, Volume: 22, Issue:4

    Topics: Adenine; Bacteriophage M13; Cytosine; DNA, Single-Stranded; DNA, Viral; Escherichia coli; Guanine; Methylnitronitrosoguanidine; Mutagenesis; Mutagens; Transfection; Ultraviolet Rays

1996
DNA methylation by tert-butyl hydroperoxide-iron (II): a role for the transition metal ion in the production of DNA base adducts.
    Chemico-biological interactions, 1999, Apr-01, Volume: 118, Issue:2

    Topics: Adenine; Animals; Cattle; Chelating Agents; Copper; DNA Adducts; DNA Methylation; Electron Spin Resonance Spectroscopy; Free Radicals; Guanine; Iron; Molecular Structure; tert-Butylhydroperoxide

1999
The cytotoxicity of DNA carboxymethylation and methylation by the model carboxymethylating agent azaserine in human cells.
    Carcinogenesis, 1999, Volume: 20, Issue:9

    Topics: Adenine; Alkylating Agents; Azaserine; Azo Compounds; Burkitt Lymphoma; Carcinogens; DNA Adducts; DNA Damage; DNA Methylation; Drug Resistance; Enzyme Induction; Genetic Complementation Test; Glycine; Guanine; Humans; Lymphocytes; Methylation; O(6)-Methylguanine-DNA Methyltransferase; Tumor Cells, Cultured; Xeroderma Pigmentosum

1999
Sensitivity of human type II topoisomerases to DNA damage: stimulation of enzyme-mediated DNA cleavage by abasic, oxidized and alkylated lesions.
    Nucleic acids research, 2000, May-01, Volume: 28, Issue:9

    Topics: Adenine; Alkylation; Apurinic Acid; Base Sequence; DNA; DNA Adducts; DNA Damage; DNA Repair; DNA Topoisomerases, Type II; DNA-Binding Proteins; Guanine; Humans; Isoenzymes; Mutation; Oligonucleotides; Oxidation-Reduction; Plasmids; Sensitivity and Specificity

2000
Induction of apoptosis and inhibition of signalling pathways by alkylated purines.
    Mutagenesis, 2000, Volume: 15, Issue:4

    Topics: Adenine; Alkylation; Androstadienes; Animals; Antibiotics, Antineoplastic; Apoptosis; Cell Line; Cricetinae; DNA Fragmentation; Electrophoresis, Agar Gel; Enzyme Inhibitors; Fibroblasts; G1 Phase; Genes, p53; Guanine; MAP Kinase Signaling System; Mutation; Phosphorylation; Purines; Resting Phase, Cell Cycle; Ribosomal Protein S6 Kinases; Signal Transduction; Sirolimus; Wortmannin

2000
Evidence for the involvement of lesions other than O6-alkylguanine in mammalian cell mutagenesis.
    Carcinogenesis, 1980, Volume: 1, Issue:9

    Topics: Adenine; Alkylating Agents; Animals; Carcinogens; Cricetinae; DNA; DNA Damage; Drug Resistance; Guanine; Hypoxanthine Phosphoribosyltransferase; Methyl Methanesulfonate; Methylnitrosourea; Mutagenesis; Mutagens; Sulfuric Acid Esters; Thioguanine

1980
Monitoring of dimethyl sulphate-induced N3-methyladenine, N7-methylguanine and O(6)-methylguanine DNA adducts using reversed-phase high performance liquid chromatography and mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008, May-01, Volume: 867, Issue:1

    Topics: Adenine; Animals; Chromatography, High Pressure Liquid; DNA; DNA Adducts; Guanine; Male; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Sulfuric Acid Esters; Testis

2008
Gas-phase thermochemical properties of the damaged base O(6)-methylguanine versus adenine and guanine.
    The Journal of organic chemistry, 2009, Oct-02, Volume: 74, Issue:19

    Topics: Adenine; Computer Simulation; Gases; Guanine; Kinetics; Models, Chemical; Thermodynamics

2009
The removal of alkylation products from the DNA of Escherichia coli cells treated with the carcinogens N-ethyl-N-nitrosourea and N-methyl-N-nitrosourea: influence of growth conditions and DNA repair defects.
    Carcinogenesis, 1980, Volume: 1, Issue:1

    Topics: Adenine; Alkylating Agents; Alkylation; Carcinogens; DNA Repair; DNA, Bacterial; Escherichia coli; Ethylnitrosourea; Guanine; Methylation; Methylnitrosourea

1980
Optimization of global DNA methylation measurement by LC-MS/MS and its application in lung cancer patients.
    Analytical and bioanalytical chemistry, 2013, Volume: 405, Issue:27

    Topics: Adenine; Adenocarcinoma; Aged; Carcinoma, Squamous Cell; Chromatography, Liquid; Deoxycytidine; DNA Methylation; DNA, Neoplasm; Female; Fungal Proteins; Guanine; Humans; Indicator Dilution Techniques; Limit of Detection; Lung Neoplasms; Male; Middle Aged; Reproducibility of Results; Single-Strand Specific DNA and RNA Endonucleases; Solid Phase Extraction; Tandem Mass Spectrometry; Tumor Microenvironment

2013
In vitro lesion bypass by human PrimPol.
    DNA repair, 2018, Volume: 70

    Topics: Adenine; DNA Damage; DNA Primase; DNA-Directed DNA Polymerase; Guanine; Humans; Magnesium; Multifunctional Enzymes; Uracil

2018