adenine and n 0861

adenine has been researched along with n 0861 in 20 studies

Research

Studies (20)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	18 (90.00)	18.2507
2000's	2 (10.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Hurt, CM; Pelleg, A	1
Martin, PL	1
Barrett, RJ; Droppleman, DA; Wright, KF	1
Belardinelli, L; Shryock, JC; Travagli, HC	1
Barrett, RJ; Beller, GA; Glover, DK; Ruiz, M; Sansoy, V	1
Iskandrian, AS	1
Marala, RB; Mustafa, SJ	1
Martin, PL; May, JM	1
Barrett, R; Belardinelli, L; Rush, W; Sidi, A; Wesley, R	1
Barrett, RJ; Wright, KF	1
Porzio, D; Sadeghi, M; Wesley, RC	1
Hurt, CM; Pelleg, A; Tong, H; Wang, L; Xu, J	1
Martin, PL; McKenna, DG; Potts, AA; Sykes, AM	1
Barrett, RJ; Linden, J; Martin, PL; May, JM; Wysocki, RJ	1
Belardinelli, L; Bertolet, BD; Franco, EA; Hill, JA; Kerensky, RA; Nichols, WW	1
Barrett, RJ	1
Giannella, E; Levi, R; Mochmann, HC	1
Barbey, JT; Benton, RE; Douyon, E; Nagashima, S; Woosley, RL; Yasuda, SU	1
Auchampach, JA; Bhattacharya, S; Black, RG; Bolli, R; Kodani, E; Takano, H; Tang, XL; Yang, Z	1
Fahim, M; Mustafa, SJ	1

Reviews

1 review(s) available for adenine and n 0861

Article	Year
Realizing the potential of adenosine-receptor-based therapeutics. Proceedings of the Western Pharmacology Society, 1996, Volume: 39 Topics: Adenine; Animals; Clinical Trials as Topic; Humans; Norbornanes; Pain; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrazoles; Pyridines; Receptors, Purinergic P1; Renal Insufficiency; Theophylline	1996

Trials

1 trial(s) available for adenine and n 0861

Article	Year
Adenosine A1-receptor occupancy predicts A1-receptor antagonist effects of N-0861. Clinical pharmacology and therapeutics, 1998, Volume: 64, Issue:5 Topics: Adenine; Adult; Aged; Atrioventricular Node; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Administration Schedule; Electrocardiography; Female; Humans; Infusions, Intravenous; Injections, Intravenous; Male; Middle Aged; Norbornanes; Purinergic P1 Receptor Antagonists	1998

Article

Year

Adenosine A1-receptor occupancy predicts A1-receptor antagonist effects of N-0861.

Clinical pharmacology and therapeutics, 1998, Volume: 64, Issue:5

Topics: Adenine; Adult; Aged; Atrioventricular Node; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Administration Schedule; Electrocardiography; Female; Humans; Infusions, Intravenous; Injections, Intravenous; Male; Middle Aged; Norbornanes; Purinergic P1 Receptor Antagonists

1998

Other Studies

18 other study(ies) available for adenine and n 0861

Article	Year
Effects of N6-endonorbornan-2-yl-9-methyladenine, N0861, on negative chronotropic and vasodilatory actions of adenosine in the canine heart in vivo. Canadian journal of physiology and pharmacology, 1992, Volume: 70, Issue:11 Topics: Adenine; Adenosine; Animals; Coronary Vessels; Depression, Chemical; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Injections, Intravenous; Male; Norbornanes; Purinergic Antagonists; Vasodilation	1992
Evidence that adenosine receptors in the dog left atrium are not of the typical A1 or A2 adenosine receptor subtypes. European journal of pharmacology, 1992, Apr-22, Volume: 214, Issue:2-3 Topics: Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Dogs; Female; Heart Atria; In Vitro Techniques; Male; Myocardium; Norbornanes; Receptors, Purinergic; Theophylline; Vasodilation; Xanthines	1992
N-0861 selectively antagonizes adenosine A1 receptors in vivo. European journal of pharmacology, 1992, May-27, Volume: 216, Issue:1 Topics: Adenine; Adenosine; Animals; Dose-Response Relationship, Drug; Heart Rate; Injections, Intravenous; Male; Norbornanes; Purinergic Antagonists; Rats; Rats, Inbred Strains; Theophylline; Vasodilation	1992
Evaluation of N-0861, (+-)-N6-endonorbornan-2-yl-9-methyladenine, as an A1 subtype-selective adenosine receptor antagonist in the guinea pig isolated heart. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:3 Topics: Adenine; Adenosine; Animals; Carrier Proteins; Coronary Vessels; Guinea Pigs; Heart; Heart Conduction System; Hypoxia; In Vitro Techniques; Membrane Proteins; Norbornanes; Nucleoside Transport Proteins; Perfusion; Receptors, Purinergic; Vasodilation	1992
Effect of N-0861, a selective adenosine A1 receptor antagonist, on pharmacologic stress imaging with adenosine. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1995, Volume: 36, Issue:2 Topics: Adenine; Adenosine; Animals; Coronary Circulation; Coronary Disease; Dogs; Exercise Test; Hemodynamics; Norbornanes; Purinergic P1 Receptor Antagonists; Radionuclide Imaging; Thallium Radioisotopes; Vasodilation	1995
New directions in pharmacologic stress imaging. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1995, Volume: 36, Issue:2 Topics: Adenine; Adenosine; Animals; Coronary Circulation; Coronary Disease; Dogs; Hemodynamics; Norbornanes; Purinergic P1 Receptor Antagonists	1995
Adenosine analogues prevent phorbol ester-induced PKC depletion in porcine coronary artery via A1 receptor. The American journal of physiology, 1995, Volume: 268, Issue:1 Pt 2 Topics: Adenine; Adenosine; Animals; Coronary Vessels; Dose-Response Relationship, Drug; Endothelins; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norbornanes; Phenethylamines; Phorbol 12,13-Dibutyrate; Protein Kinase C; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Receptors, Purinergic P2; Swine	1995
Identification and functional characterization of A1 and A2 adenosine receptors in the rat vas deferens: a comparison with A1 receptors in guinea pig left atrium and A2 receptors in guinea pig aorta. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 269, Issue:3 Topics: Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta; Guinea Pigs; Heart; In Vitro Techniques; Male; Norbornanes; Phenethylamines; Rats; Receptors, Purinergic P1; Theophylline; Vas Deferens; Xanthines	1994
Cardiovascular effects of a non-xanthine-selective antagonist of the A1 adenosine receptor in the anaesthetised pig: pharmacological and therapeutic implications. Cardiovascular research, 1994, Volume: 28, Issue:5 Topics: Adenine; Adenosine; Anesthesia; Animals; Atropine; Cardiovascular System; Coronary Vessels; Female; Heart; Male; Norbornanes; Propranolol; Purinergic P1 Receptor Antagonists; Regional Blood Flow; Swine; Theophylline	1994
A selective adenosine A1 receptor antagonist attenuates renal dysfunction during controlled hypotension with adenosine in rats. Anesthesia and analgesia, 1994, Volume: 79, Issue:3 Topics: Adenine; Adenosine; Animals; Blood Pressure; Hypotension, Controlled; Kidney; Male; Norbornanes; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley	1994
Effect of selective A1 adenosine receptor antagonism of postdefibrillation cardiovascular depression: evidence for an antiadrenergic role of endogenous adenosine. Cardiovascular research, 1993, Volume: 27, Issue:1 Topics: Adenine; Adenosine; Animals; Electric Countershock; Female; Heart; Male; Myocardial Contraction; Norbornanes; Propranolol; Purinergic Antagonists; Receptors, Adrenergic; Swine	1993
Endogenous adenosine, A1 adenosine receptor, and pertussis toxin sensitive guanine nucleotide binding protein mediate hypoxia induced AV nodal conduction block in guinea pig heart in vivo. Cardiovascular research, 1993, Volume: 27, Issue:1 Topics: Adenine; Adenosine; Animals; Female; GTP-Binding Proteins; Guinea Pigs; Heart; Heart Block; Male; Myocardial Ischemia; Norbornanes; Pertussis Toxin; Purinergic Antagonists; Receptors, Purinergic; Virulence Factors, Bordetella	1993
(+-)-N6-endonorbornan-2-yl-9-methyladenine (N-0861) and its enantiomers: selective antagonists of A1-adenosine receptors in guinea pig isolated atria. The Journal of pharmacology and experimental therapeutics, 1993, Volume: 265, Issue:1 Topics: Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta; Drug Antagonism; Guinea Pigs; Heart; Heart Atria; In Vitro Techniques; Male; Muscle Relaxation; Norbornanes; Purinergic Antagonists; Stereoisomerism; Vasodilator Agents	1993
Characterization of 8-(N-methylisopropyl)amino-N6-(5'-endohydroxy- endonorbornyl)-9-methyladenine (WRC-0571), a highly potent and selective, non-xanthine antagonist of A1 adenosine receptors. The Journal of pharmacology and experimental therapeutics, 1996, Volume: 276, Issue:2 Topics: Adenine; Animals; Cattle; Guinea Pigs; Heart Rate; Humans; In Vitro Techniques; Male; Norbornanes; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship	1996
Selective attenuation by N-0861 (N6-endonorboran-2-yl-9-methyladenine) of cardiac A1 adenosine receptor-mediated effects in humans. Circulation, 1996, May-15, Volume: 93, Issue:10 Topics: Adenine; Adenosine; Aged; Coronary Circulation; Dose-Response Relationship, Drug; Female; Heart; Humans; Male; Middle Aged; Norbornanes; Pain; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1	1996
Ischemic preconditioning prevents the impairment of hypoxic coronary vasodilatation caused by ischemia/reperfusion: role of adenosine A1/A3 and bradykinin B2 receptor activation. Circulation research, 1997, Volume: 81, Issue:3 Topics: Adenine; Adenosine; Animals; Bradykinin; Bradykinin Receptor Antagonists; Coronary Vessels; Guinea Pigs; Hypoxia; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Male; Myocardial Reperfusion Injury; Nitric Oxide; Nitric Oxide Synthase; Norbornanes; Receptor, Adenosine A3; Receptor, Bradykinin B2; Receptors, Bradykinin; Receptors, Purinergic P1; Vasodilation	1997
A(1) or A(3) adenosine receptors induce late preconditioning against infarction in conscious rabbits by different mechanisms. Circulation research, 2001, Mar-16, Volume: 88, Issue:5 Topics: Adenine; Adenosine; Animals; Binding, Competitive; Cell Line; Consciousness; Decanoic Acids; Humans; Hydroxy Acids; Iodine Radioisotopes; Ischemic Preconditioning, Myocardial; Membranes; Myocardial Infarction; Nitroarginine; Norbornanes; Phenethylamines; Rabbits; Radioligand Assay; Receptor, Adenosine A3; Receptors, Purinergic P1	2001
Evidence for the presence of A(1) adenosine receptors in the aorta of spontaneously hypertensive rats. British journal of pharmacology, 2001, Volume: 134, Issue:8 Topics: Adenine; Adenosine; Animals; Aorta; Culture Techniques; Dose-Response Relationship, Drug; Endothelium, Vascular; Free Radical Scavengers; Hypertension; Indomethacin; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norbornanes; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Theobromine; Vasodilation	2001