adenine has been researched along with mercaptopurine in 79 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 68 (86.08) | 18.7374 |
1990's | 3 (3.80) | 18.2507 |
2000's | 6 (7.59) | 29.6817 |
2010's | 2 (2.53) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
Seegmiller, JE; Shreier, MH; Waldmann, TA; Watanabe, T | 1 |
Agris, PF; Tompson, JG | 1 |
Dusanic, DG | 1 |
Gabrielsen, AE; Meuwissen, HJ; Moore, JJ; Pickering, RJ; Pollara, B | 1 |
Chenon, MT; Grant, DM; Panzica, RP; Pugmire, RJ; Townsend, LB | 2 |
Akiyama, Y; Hashimoto, H; Kitoh, T; Kubota, M; Mikawa, H; Shimizu, T; Takimoto, T | 1 |
Brajter-Toth, A; Volk, KJ; Yost, RA | 1 |
Ribeiro, LP | 1 |
Krepelka, J; Melka, M; Miko, M | 1 |
Kummer, D | 1 |
Hewson, K; Montgomery, JA | 1 |
Brown, GB; Sugiura, K | 1 |
Loeffler, JE; Mason, MI; Van Overbeek, J | 1 |
Coonrod, JD; Eickhoff, TC | 1 |
Holmes, EW; Kelley, WN; Pehlke, DM | 1 |
Flosdorf, J; Marutzky, R; Peterssen-Borstel, H | 1 |
Jezewska, MM | 1 |
Moiseenko, EV; Shust, AI; Tolstykh, LY | 1 |
Königk, E; Walter, RD | 1 |
Rosman, M; Williams, HE | 1 |
Creasey, WA; Lee, MH; Rosman, M; Sartorelli, AC | 1 |
Wilmanns, W | 1 |
Pickering, WR; Woods, RA | 1 |
Murphy, AJ | 1 |
Caldwell, IC; Chan, MC; Henderson, JF; Lau, KF; Paterson, AR; Paul, B | 1 |
Bragonier, JR; Carver, MJ | 1 |
Chirvasie, R; Dincă, A; Păuşescu, E | 1 |
Doctor, VM | 1 |
Benke, PJ; Herrick, N | 1 |
Mendonça, LC; Travassos, LR | 1 |
Chao, DL; Kimball, AP | 1 |
Sims, L | 1 |
Aaron, JJ; Winefordner, JD | 1 |
Davidson, JD | 1 |
Caldwell, IC | 1 |
Brown, GB; Parham, JC; Sugiura, K; Teller, MN | 1 |
Allan, PW; Hill, DL; Straight, S | 1 |
Hill, DL | 1 |
Blair, DG; Cross, DC; Peesker, SJ | 1 |
Oriuchi, T | 1 |
Brockman, RW; Dixon, GJ; Dulmadge, EA; Shaddix, SC | 1 |
Caldwell, IC; Henderson, JF; Kelley, WN; Rosenbloom, FM; Seegmiller, JE | 1 |
Henderson, JF; Kelly, WN; Rosenbloom, FM; Seegmiller, JE | 1 |
Kano, A | 1 |
St Geme, JW | 1 |
Cook, JM; Franklin, TJ | 1 |
Cruz, FS; Moreira, Mdo C; Travassos, LR | 1 |
Burchenal, JH; Butterbaugh, J; Dollinger, M; Giner-Sorolla, A; Stoll, D | 1 |
Baker, BR; Erickson, EH | 1 |
Al-Safi, SA; Maddocks, JL | 1 |
Gordon, PB; Seglen, PO | 1 |
Inui, N; Sato, S; Takizawa, H | 1 |
Bökkerink, JP; De Abreu, RA; Keizer-Garritsen, JJ; Lambooy, LH; Stet, EH; Trijbels, FJ; Vogels-Mentink, TM | 1 |
Innocenti, F; Iyer, L; Ratain, MJ | 1 |
LAW, LW | 1 |
FJELDE, A | 1 |
BALIS, ME; PECORA, P; SALSER, JS | 1 |
JEFFREY, JJ; SCHANKER, LS; TOCCO, DJ | 1 |
KALYANKAR, GD; MANSOOR, M; TALWAR, GP | 1 |
MAGASANIK, B; ZIMMERMAN, EF | 1 |
KARNOFSKY, DA; SIMMEL, EB | 1 |
BRAGONIER, JR; CARVER, MJ; ROESKY, N | 1 |
BIEBER, AL; BOOTH, BA; SARTORELLI, AC; UPCHURCH, HF | 1 |
BRINDLE, SD; HIRSCHBERG, E; SEMENTE, G | 1 |
LEVY, RN; RUOHANI, J; SAWITSKY, A | 1 |
GUTHRIE, R; LU, WC | 1 |
JUNGA, IG; LEPAGE, GA | 1 |
HOEHN, RJ | 1 |
ATKINSON, MR; MURRAY, AW | 2 |
BROCKMAN, RW; CHUMLEY, S | 1 |
Rappaport, HP | 1 |
Jena, G; Kalra, S; Mukhopadhyay, AK; Tikoo, K | 1 |
Closs, EI; Fischer, C; Fritz, P; Fromm, MF; Gödtel-Armbrust, U; Gradhand, U; Habermeier, A; Janke, D; Lang, T; Mehralivand, S; Nürnberg, P; Schwab, M; Strand, D; Toliat, MR; Wojnowski, L; Zanger, UM | 1 |
Cole, SP; Hoque, MT | 1 |
Tang, W; Zeng, X; Zhang, M | 1 |
4 review(s) available for adenine and mercaptopurine
Article | Year |
---|---|
Immunological aspects of purine metabolism.
Topics: Adenine; Adenosine; Adenosine Deaminase; Antibody Formation; Hormones; Humans; Immunity, Cellular; Immunologic Deficiency Syndromes; Immunosuppression Therapy; Inosine; Lesch-Nyhan Syndrome; Liver; Lymphocyte Activation; Lymphocytes; Mercaptopurine; Models, Biological; Nucleoside Deaminases; Pentosyltransferases; Purine-Nucleoside Phosphorylase; Purines; Synaptic Transmission; Uridine | 1977 |
Immunosuppression and ablastin.
Topics: Adenine; Animals; Antibodies; Antibody Formation; Antilymphocyte Serum; Cyclophosphamide; Dexamethasone; DNA; Female; Immunosuppression Therapy; Male; Mercaptopurine; Mice; Mononuclear Phagocyte System; Pregnancy; Rats; Reproduction; Sodium Salicylate; Spleen; T-Lymphocytes; Thymus Gland; Trypanosoma; Trypanosomiasis | 1975 |
Pharmacogenetics: a tool for individualizing antineoplastic therapy.
Topics: Adenine; Antineoplastic Agents; Camptothecin; Dihydrouracil Dehydrogenase (NADP); Fluorouracil; Genotype; Glucuronosyltransferase; Humans; Imides; Irinotecan; Isoquinolines; Mercaptopurine; Methyltransferases; Naphthalimides; Organophosphonates; Oxidoreductases; Pharmacogenetics; Phenotype | 2000 |
EFFECTS OF GROWTH-INHIBITING CHEMICALS ON THE SAND-DOLLAR EMBRYO, ECHINARACHNIUS PARMA.
Topics: Adenine; Animals; Azaguanine; Bromodeoxyuridine; Colchicine; Dinitrophenols; Echinodermata; Embryo, Mammalian; Embryo, Nonmammalian; Enzyme Inhibitors; Floxuridine; Fluorouracil; Growth; Idoxuridine; Mercaptopurine; Pharmacology; Pyrimidines; Sea Urchins | 1963 |
75 other study(ies) available for adenine and mercaptopurine
Article | Year |
---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Production of specific site probes of tRNA structure by enrichment with carbon 13 at particular locations.
Topics: Adenine; Carbon Isotopes; Escherichia coli; Isotope Labeling; Kinetics; Magnetic Resonance Spectroscopy; Mercaptopurine; Methionine; Molecular Conformation; Nucleic Acid Conformation; Purines; RNA, Transfer; Uracil | 1979 |
Combined immunodeficiency disease: an inborn error of purine metabolism.
Topics: Adenine; Adenosine Deaminase; Chromosomes, Human, 19-20; Enzyme Inhibitors; Erythrocytes; Humans; Immunogenetics; Immunologic Deficiency Syndromes; Inosine; Isoenzymes; Lesch-Nyhan Syndrome; Liver; Lung; Lymphocytes; Mercaptopurine; Molecular Weight; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Tissue Extracts | 1975 |
Carbon-13 magnetic resonance. XXV. A basic set of parameters for the investigation of tautomerism im purines. Established from carbon-13 magnetic resonance studies using certain purines and pyrrolo[2,3-d]pyrimidines.
Topics: Adenine; Hypoxanthines; Magnetic Resonance Spectroscopy; Mercaptopurine; Purines; Pyrimidines; Pyrroles | 1975 |
Carbon-13 magnetic resonance. XXVI. A quantitative determination of the tautomeric populations of certain purines.
Topics: Adenine; Hypoxanthines; Isomerism; Magnetic Resonance Spectroscopy; Mercaptopurine; Purines | 1975 |
Biochemical basis of the prevention of 6-thiopurine toxicity by the nucleobases, hypoxanthine and adenine.
Topics: 2-Aminopurine; Adenine; Adenine Phosphoribosyltransferase; Antineoplastic Agents; Biological Transport; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Inosine Monophosphate; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Promyelocytic, Acute; Mercaptopurine; Thioguanine; Thionucleotides; Tumor Cells, Cultured | 1990 |
Characterization of solution-phase and gas-phase reactions in on-line electrochemistry-thermospray tandem mass spectrometry.
Topics: Adenine; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Electrochemistry; Gases; Hypoxanthine; Hypoxanthines; Mass Spectrometry; Mercaptopurine; Purines; Solutions | 1989 |
Inhibition of xanthine dehydrogenase from Triatoma infestans by some purine analogues.
Topics: Adenine; Animals; Disease Vectors; Ketone Oxidoreductases; Mercaptopurine; Purines; Triatoma; Triatominae; Trypanosoma cruzi; Xanthine Dehydrogenase; Xanthines | 1988 |
Inhibition of biosynthetic processes in P388 and Ehrlich ascites cells by cloturin.
Topics: Adenine; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; DNA, Neoplasm; Kinetics; Leukemia P388; Mercaptopurine; Mice; Mustard Compounds; Neoplasm Proteins; Neoplasms, Experimental; RNA, Neoplasm; Thymidine; Tumor Cells, Cultured; Uridine | 1988 |
[Effects of cytostatics and x-rays on nucleic acid metabolism of solid, malignant tumors in vitro].
Topics: Adenine; Animals; Antineoplastic Agents; Carbon Isotopes; Dactinomycin; Depression, Chemical; DNA, Neoplasm; Estriol; Fluorouracil; Formates; Glycine; Hypoxanthines; In Vitro Techniques; Leucine; Mercaptopurine; Methotrexate; Methylprednisolone; Neoplasm Proteins; Neoplasms, Experimental; Nucleosides; Orotic Acid; Radiation Effects; RNA, Neoplasm; Testosterone; Thymidine; Triaziquone; Uracil; Uridine | 1970 |
Nucleosides from homoribose.
Topics: Adenine; Chemical Phenomena; Chemistry; Chemistry, Organic; Electron Spin Resonance Spectroscopy; Mercaptopurine; Nucleosides; Organic Chemistry Phenomena; Purines | 1966 |
Purine N-oxides. XIX. On the oncogenic N-oxide derivatives of guanine and xanthine and a nononcogenic isomer of xanthine N-oxide.
Topics: Adenine; Animals; Carcinoma, Hepatocellular; Guanine; Liver Neoplasms; Mercaptopurine; Neoplasms; Neoplasms, Experimental; Oxides; Rats; Xanthines | 1967 |
Dormin (Abscisin II), inhibitor of plant DNA synthesis?
Topics: Adenine; Antimetabolites; Benzene Derivatives; Culture Techniques; Depression, Chemical; DNA; Mercaptopurine; Phosphorus Isotopes; Plant Growth Regulators; Plants; Ribosomes; RNA; Silicon Dioxide | 1967 |
Combined action of 6-mercaptopurine and antibiotics on gram-negative bacteria in vitro.
Topics: Adenine; Ampicillin; Anti-Bacterial Agents; Cephalothin; Chloramphenicol; Culture Media; Drug Synergism; Enterobacteriaceae; Escherichia coli; Gentamicins; Hypoxanthines; Kanamycin; Klebsiella; Mercaptopurine; Penicillin Resistance; Polymyxins; Pseudomonas; Streptomycin; Tetracycline; Time Factors; Xanthines | 1972 |
Human IMP dehydrogenase. Kinetics and regulatory properties.
Topics: Adenine; Adenosine; Carbon Radioisotopes; Cell Fractionation; Chromatography, DEAE-Cellulose; Chromatography, Paper; Cytosol; Female; Guanine; Guanosine; Humans; Inosine Nucleotides; Ketone Oxidoreductases; Kinetics; Mercaptopurine; Mitochondria; NAD; Placenta; Pregnancy; Purine Nucleotides; Pyrimidine Nucleotides; Structure-Activity Relationship; Ultracentrifugation | 1974 |
Large scale enzymatic synthesis of nucleoside-5'-monophosphates using a phosphotransferase from carrots.
Topics: Adenine; Aza Compounds; Chromatography, DEAE-Cellulose; Chromatography, Gel; Deoxyadenosines; Mercaptopurine; Nitrophenols; Nucleosides; Nucleotides; Oxidative Phosphorylation; Phosphates; Phosphoric Monoester Hydrolases; Phosphotransferases; Plants, Edible; Purine Nucleosides; Pyrimidines; Pyrroles; Ribonucleosides; Vegetables | 1974 |
Effect of allopurinol (4-hydroxyprazolo(3,4-d)pyrimidine) on xanthine accumulation by milk xanthine oxidase in vitro.
Topics: Adenine; Allopurinol; Animals; Antimetabolites; Aza Compounds; Azaguanine; Hypoxanthines; In Vitro Techniques; Mercaptopurine; Milk; Oxidoreductases; Purines; Spectrophotometry; Uric Acid; Xanthine Oxidase; Xanthines | 1974 |
Characteristics of mutant clones of Chinese hamster cells resistant to purine analogues.
Topics: Adenine; Animals; Azaguanine; Carbon Radioisotopes; Cell Division; Cell Survival; Clone Cells; Cricetinae; Drug Resistance; Hydrogen-Ion Concentration; Hypoxanthines; Mercaptopurine; Mutation; Pentosyltransferases; Phenotype | 1974 |
Hypoxanthine-guanine phosphoribosyltransferase and adenine phosphoribosyltransferase from Plasmodium chabaudi, purification and properties.
Topics: Adenine; Guanine; Hypoxanthines; Isoelectric Focusing; Isoenzymes; Mercaptopurine; Molecular Weight; Pentosyltransferases; Plasmodium; Thioguanine | 1974 |
Leukocyte purine phosphoribosyltransferases in human leukemias sensitive and resistant to 6-thiopurines.
Topics: Adenine; Adolescent; Adult; Aged; Antimetabolites; Drug Resistance; Female; Guanine; Humans; Hypoxanthines; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Male; Mercaptopurine; Mutation; Pentosyltransferases; Remission, Spontaneous; Thioguanine | 1973 |
Mechanisms of resistance to 6-thiopurines in human leukemia.
Topics: Adenine; Alkaline Phosphatase; Drug Resistance; Guanine; Humans; Hypoxanthines; Leukemia; Leukemia, Lymphoid; Lymphocytes; Mercaptopurine; Pentosyltransferases; Thioguanine | 1974 |
Synthesis of purine nucleotides in human and leukemic cells. Interaction of 6-mercaptopurine and allopurinol.
Topics: Adenine; Allopurinol; Bone Marrow; Bone Marrow Cells; Carbon Radioisotopes; Cell-Free System; Chromatography, Paper; Formates; Guanine Nucleotides; Humans; Hypoxanthines; Kinetics; Leucovorin; Leukemia; Leukemia, Myeloid, Acute; Leukocytes; Ligases; Mercaptopurine; Pentosephosphates; Pentosyltransferases; Spectrophotometry, Ultraviolet; Tetrahydrofolates | 1973 |
Genetics of resistance to 4-aminopyrazolo-(3,4-d)-pyrimidine in Saccharomyces cerevisiae.
Topics: Adenine; Aza Compounds; Chromosome Mapping; Crosses, Genetic; Drug Resistance, Microbial; Genes, Dominant; Genes, Recessive; Genetic Linkage; Genetics, Microbial; Guanine; Hypoxanthines; Mercaptopurine; Methylation; Purines; Pyrazoles; Pyrimidines; Saccharomyces cerevisiae; Suppression, Genetic | 1973 |
Circular dichroism of the adenine and 6-mercaptopurine nucleotide complexes of heavy meromyosin.
Topics: Adenine; Animals; Binding Sites; Circular Dichroism; Mathematics; Mercaptopurine; Molecular Weight; Myosin Subfragments; Myosins; Protein Binding; Protein Conformation; Rabbits; Spectrophotometry, Ultraviolet | 1974 |
Inhibitors of nucleoside and nucleotide metabolism.
Topics: Adenine; Adenine Nucleotides; Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Erythrocytes; Guanine; Humans; Hypoxanthines; Mercaptopurine; Neoplasms; Nucleosides; Nucleotides; Pentosyltransferases; Phosphotransferases; Purines; Pyrimidines; Thioguanine | 1972 |
The influence of 6-mercaptopurine on rat placenta and fetus.
Topics: Abnormalities, Drug-Induced; Adenine; Animals; Chromatography; DNA; Female; Fetus; Glycine; Guanine; Mercaptopurine; Placenta; Pregnancy; Pregnancy, Animal; Rats; RNA; Spinal Dysraphism; Spine | 1968 |
[On the effects of immunosuppressive and cytostatic substances on the oxidative metabolism of leukocytes during the rejection of kidney homotransplants].
Topics: Adenine; Animals; Antigen-Antibody Reactions; Antineoplastic Agents; Citric Acid Cycle; Cyclophosphamide; Dogs; Immunosuppressive Agents; In Vitro Techniques; Ketoglutaric Acids; Kidney Transplantation; Leukocytes; Mercaptopurine; Oxidation-Reduction; Succinates; Time Factors; Transplantation Immunology; Transplantation, Homologous; Triaziquone | 1968 |
Inhibition of methotrexate resistant mutant of Streptococcus faecalis by analogs of purine and pyrimidine.
Topics: Adenine; Adenine Nucleotides; Azaguanine; Drug Resistance, Microbial; Enterococcus faecalis; Guanine; Kinetics; Mercaptopurine; Methotrexate; Mutation; Nucleosides; Purines; Pyrimidines; Thioguanine; Thymine | 1970 |
Azaguanine-resistance as a manifestation of a new form of metabolic overproduction of uric acid.
Topics: Adenine; Adolescent; Aminopterin; Azaguanine; Blood Urea Nitrogen; Carbon Isotopes; Cell Line; Creatinine; Drug Resistance; Electrophoresis, Starch Gel; Erythrocytes; Fibroblasts; Gout; Guanine; Humans; Hypoxanthines; Lesch-Nyhan Syndrome; Male; Mercaptopurine; Pentosyltransferases; Purines; Uric Acid | 1972 |
Metabolism of ethionine in ethionine-sensitive and ethionine-resistant cells of the enteric yeast Candida slooffii.
Topics: Adenine; Amino Acids; Candida; Carbon Isotopes; Cell Fractionation; Choline; Chromatography, Paper; Culture Media; Depression, Chemical; Drug Resistance, Microbial; Ethionine; Genetics, Microbial; Mercaptopurine; Methionine; Mutation; Phenylalanine; Purines; Pyrimidines; Stereoisomerism; Tritium | 1972 |
Deamination of arabinosyladenine by adenosine deaminase and inhibition by arabinosyl-6-mercaptopurine.
Topics: Adenine; Adenosine; Aminohydrolases; Animals; Antibiotics, Antineoplastic; Arabinose; Cell Fractionation; Cell Line; Deamination; Drug Resistance; Female; Leukemia L1210; Mercaptopurine; Mice; Mice, Inbred Strains; Mutation; Nucleosides | 1972 |
Drugs used in radiotherapy.
Topics: Adenine; Alkylating Agents; Analgesics; Anemia; Anti-Bacterial Agents; Antiemetics; Antimetabolites; Antineoplastic Agents; Drug Therapy; Expectorants; Folic Acid; Humans; Mercaptopurine; Methotrexate; Neoplasms; Pharmaceutical Preparations; Radiotherapy; Steroids; Tranquilizing Agents; Vitamins | 1972 |
Analytical study of the phosphorescence of purines in aqueous solution at 77 degrees K.
Topics: Adenine; Fluorescence; Hydrogen-Ion Concentration; Mercaptopurine; Purines; Spectrometry, Fluorescence; Temperature; Water | 1972 |
Formal discussion on resistance to purine antagonists in experimental leukemia systems.
Topics: Adenine; Animals; Guanine; Humans; Hypoxanthines; In Vitro Techniques; Leukemia, Lymphoid; Leukemia, Myeloid; Mercaptopurine; Mice; Nucleotidyltransferases | 1965 |
Ion-exchange chromatography of tissue nucleotides.
Topics: Adenine; Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Chromatography, Ion Exchange; Guanine; Liver; Mercaptopurine; Mice; Nucleosides; Nucleotides; Spectrophotometry; Tissue Extracts | 1969 |
A comparison of the oncogenicities of 3-hydroxyxanthine, guanine 3-N-oxide, and some related compounds.
Topics: Adenine; Animals; Chemical Phenomena; Chemistry; Female; Granuloma; Guanine; Injections, Subcutaneous; Liver Neoplasms; Male; Mercaptopurine; Neoplasms, Experimental; Oxides; Purines; Rats; Xanthines | 1970 |
Use of Tetrahymena pyriformis to evaluate the effects of purine and pyrimidine analogs.
Topics: Adenine; Animals; Antimetabolites; Culture Media; Mercaptopurine; Nucleosides; Purines; Pyrimidines; Tetrahymena; Thioguanine | 1970 |
Hypoxanthine phosphoribosyltransferase and guanine metabolism of adenocarcinoma 755 cells.
Topics: Adenine; Adenocarcinoma; Buffers; Carbon Isotopes; Guanine; Hydrogen-Ion Concentration; Hypoxanthines; In Vitro Techniques; Kinetics; Mercaptopurine; Neoplasms, Experimental; Nucleotides; Purines; Thioguanine; Transferases | 1970 |
The toxicity of adenine and of purine-analogs to 2,6-diamino-purine-sensitive and -resistant L-strain mouse cells.
Topics: Adenine; Albumins; Amino Acids; Aminobenzoates; Animals; Culture Media; Hypoxanthines; Imidazoles; L Cells; Mercaptopurine; Mice; Nucleosides; Pantothenic Acid; Purines; Pyrimidines; Thiamine; Thioguanine; Triazoles | 1970 |
[On uptake of 5-FU, 6-MP and methotrexate by ehrlich ascites tumor cells in vitro].
Topics: Adenine; Animals; Carcinoma, Ehrlich Tumor; Cell Membrane; Fluorouracil; In Vitro Techniques; Male; Mercaptopurine; Methotrexate; Mice; Sulfur Isotopes; Time Factors; Tritium; Uracil | 1970 |
Feedback inhibition of purine biosynthesis in adenocarcinoma 755 and sarcoma 180 cells in culture.
Topics: Adenine; Adenocarcinoma; Animals; Azaserine; Carbon Isotopes; Cell Line; Feedback; Hypoxanthines; Mercaptopurine; Methotrexate; Neoplasms, Experimental; Nucleotides; Phosphotransferases; Purines; Sarcoma 180; Thioguanine | 1970 |
Biochemical bases of accelerated purine biosynthesis de novo in human fibroblasts lacking hypoxanthine-guanine phosphoribosyltransferase.
Topics: Adenine; Adenine Nucleotides; Adolescent; Adult; Athetosis; Biopsy; Carbon Isotopes; Child; Child, Preschool; Chorea; Chromatography, Gel; Culture Techniques; Feedback; Female; Fibroblasts; Formates; Guanine; Guanine Nucleotides; Humans; Hypoxanthines; Intellectual Disability; Male; Mercaptopurine; Nucleotides; Purines; Self Mutilation; Spasm; Transferases; Tritium | 1968 |
Accelerated purine biosynthesis de novo in skin fibroblasts deficient in hypoxanthine--guanine phosphoribosyltransferase activity.
Topics: Adenine; Adenine Nucleotides; Carbon Isotopes; Depression, Chemical; Erythrocytes; Feedback; Fibroblasts; Formates; Guanine; Humans; Hypoxanthines; Mercaptopurine; Metabolic Diseases; Nucleosides; Purines; Skin; Stimulation, Chemical; Transferases; Tritium | 1968 |
[Nucleic acid metabolism of leukemic leukocytes. 2. The effect of 6-mercaptopurine on nucleic acid metabolism of leukemic leukocytes].
Topics: Adenine; Carbon Isotopes; Guanine; Humans; Hypoxanthines; Leukemia; Leukocytes; Mercaptopurine; Nucleic Acids; Purines | 1968 |
The action of 6-mercaptopurine in human heteroploid cells.
Topics: Adenine; Antiviral Agents; Biological Assay; Culture Techniques; Hypoxanthines; Imidazoles; Imides; Mercaptopurine; Nucleosides; Vaccinia virus | 1969 |
The inhibition of nucleic acid synthesis by mycophenolic acid.
Topics: Adenine; Animals; Antibiotics, Antineoplastic; Caproates; DNA, Neoplasm; Guanine; Guanine Nucleotides; Hypoxanthines; In Vitro Techniques; L Cells; Mercaptopurine; Mice; Neoplasms, Experimental; Oxidoreductases; Rats; Sarcoma, Yoshida; Thymidine | 1969 |
[Action of ethylic urethane on the growth of Candida slooffii].
Topics: Adenine; Amino Acids; Candida; Mercaptopurine; Urethane | 1965 |
Studies of 6-N-hydroxylamino-9-beta-D-ribofuranosylpurine in mouse leukemia.
Topics: Adenine; Animals; Body Weight; Cytarabine; Drug Antagonism; Drug Synergism; Fluorouracil; Guanine; Leukemia; Leukemia L1210; Mercaptopurine; Methotrexate; Mice; Nucleosides; Phosphotransferases; Purines; Vincristine | 1967 |
Irreversible enzyme inhibitors. 98. Hydrophobic interactions with succinoadenylate kinosynthetase and 9-substituted adenines.
Topics: Adenine; Chemical Phenomena; Chemistry; Ligases; Mercaptopurine | 1967 |
Azathioprine and 6-mercaptopurine (6-MP) suppress the human mixed lymphocyte reaction (MLR) by different mechanisms.
Topics: Adenine; Adenosine; Aminoimidazole Carboxamide; Azathioprine; DNA; Guanine; Humans; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Lymphocyte Culture Test, Mixed; Lymphocytes; Mercaptopurine; Xanthine; Xanthines | 1984 |
6-substituted purines: a novel class of inhibitors of endogenous protein degradation in isolated rat hepatocytes.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Liver; Lysosomes; Male; Mercaptopurine; Proteins; Purines; Puromycin Aminonucleoside; Rats; Rats, Inbred Strains | 1982 |
Mouse strain differences in induction of micronuclei by base analogues and nucleosides.
Topics: Adenine; Animals; Bromodeoxyuridine; Bromouracil; Cytarabine; Erythrocytes; Female; Floxuridine; Guanosine; Mercaptopurine; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Micronucleus Tests; Mitogens; Nucleosides; Purines; Pyrimidines; Species Specificity; Thymidine; Uridine | 1993 |
Reversal of methylmercaptopurine ribonucleoside cytotoxicity by purine ribonucleosides and adenine.
Topics: Adenine; Adenosine; Antineoplastic Agents; Cell Division; Cell Survival; Cells, Cultured; Guanosine; Humans; Inosine; Mercaptopurine; Methylthioinosine; Nucleosides; Nucleotides; Purine Nucleosides; Ribonucleosides; T-Lymphocytes; Thioinosine; Thionucleotides | 1995 |
Resistance in leukemic cells to an adenine antagonist, 6-mercaptopurine.
Topics: Adenine; Animals; Humans; Leukemia, Experimental; Mercaptopurine; Purines | 1953 |
The effect of two purine analogs on a human tumor in tissue culture.
Topics: Adenine; Animals; Antimetabolites; Carcinoma; Carcinoma, Squamous Cell; Humans; Mercaptopurine; Neoplasms; Neoplasms, Experimental | 1956 |
STUDIES OF COMPOUNDS THAT INHIBIT CELL GROWTH.
Topics: Acridines; Adenine; Animals; Carcinoma; Carcinoma, Ehrlich Tumor; DNA; DNA, Neoplasm; Guanine; Liver; Mercaptopurine; Mice; Neoplasms; Nucleotides; Pharmacology; Proteins; Research | 1963 |
INTERACTION OF PURINES WITH THE PYRIMIDINE TRANSPORT PROCESS OF THE SMALL INTESTINE.
Topics: Adenine; Caffeine; Carbon Isotopes; Guanine; Intestine, Small; Intestines; Mercaptopurine; Pharmacology; Physiology; Purines; Pyrimidines; Rats; Research; Theobromine; Theophylline; Uracil; Uric Acid; Xanthines | 1963 |
BRAIN GUANINE DEAMINASE: PURIFICATION, PROPERTIES AND REGIONAL DISTRIBUTION.
Topics: Adenine; Adenine Nucleotides; Aminohydrolases; Animals; Brain; Cerebral Cortex; Guanine; Guanine Deaminase; Guanine Nucleotides; Haplorhini; Hydrogen-Ion Concentration; Mercaptopurine; Nucleosides; Rats; Research; Sheep; Spectrum Analysis; Thalamus | 1963 |
UTILIZATION AND INTERCONVERSION OF PURINE BASES AND RIBONUCLEOSIDES BY SALMONELLA TYPHIMURIUM.
Topics: Adenine; Adenine Nucleotides; Carbon Isotopes; Chromatography; Culture Media; Guanine; Guanine Nucleotides; Histidine; Mercaptopurine; Metabolism; Nucleosides; Purines; Research; Ribonucleosides; Salmonella typhimurium; Spectrophotometry | 1964 |
TERATOGENESIS: EFFECTS OF SUBSTITUTED PURINES AND THE INFLUENCE OF 4-HYDROXYPYRAZOLOPYRIMIDINE IN THE RAT.
Topics: Abnormalities, Drug-Induced; Adenine; Female; Mercaptopurine; Neoplasms; Neoplasms, Experimental; Pharmacology; Placenta; Pregnancy; Purines; Pyrazoles; Pyrimidines; Rats; Research; Teratogenesis; Thioguanine; Toxicology | 1964 |
SOME METABOLIC EFFECTS EXERTED BY AZASERINE AND PURINE ANALOGS IN VIVO.
Topics: Adenine; Amino Acids; Animals; Antimetabolites; Antineoplastic Agents; Azaserine; Carbon Isotopes; Glycine; Guanine; Mercaptopurine; Metabolism; Mice; Neoplasm Transplantation; Nucleotides; Pharmacology; Purines; Research; Sarcoma 180 | 1964 |
DEVELOPMENT AND PROPERTIES OF MOUSE LEUKEMIA L1210 RESISTANT TO MIRACIL D.
Topics: Adenine; Animals; Azaguanine; Cyclophosphamide; Enzyme Inhibitors; Folic Acid; Glutamates; Guanine; Leucovorin; Leukemia L1210; Lucanthone; Mercaptopurine; Methotrexate; Mice; Pharmacology; Proadifen; Pyridoxine; Research; Thioguanine | 1964 |
DRUG FEVER PRODUCED BY SIX-MERCAPTOPURINE.
Topics: Adenine; Antineoplastic Agents; Drug Therapy; Fever; Hematocrit; Leukemia; Leukocyte Count; Mercaptopurine; Purines; Thioguanine; Toxicology | 1964 |
ANTAGONISM BETWEEN PURINES IN PURINE-REQUIRING BACILLUS SUBTILIS MUTANTS.
Topics: 2-Aminopurine; Adenine; Adenine Nucleotides; Azaguanine; Bacillus subtilis; Guanine; Guanine Nucleotides; Hypoxanthines; Mercaptopurine; Metabolism; Mutation; Nucleosides; Nucleotides; Pharmacology; Purines; Research; Xanthines | 1964 |
METABOLISM OF PURINE NUCLEOSIDE ANALOGS.
Topics: Adenine; Animals; Antimetabolites; Guanine; Mercaptopurine; Metabolism; Mice; Neoplasms; Neoplasms, Experimental; Nucleosides; Purine Nucleosides; Purines; Research | 1965 |
INDUCTION OF TOLERANCE TO MOUSE TAIL SKIN HOMOGRAFTS BY COMBINING PAIRED IMMUNOSUPPRESSIVE AGENTS AND CELLULAR ANTIGENS.
Topics: Adenine; Allografts; Animals; Antigens; Azathioprine; Bromodeoxyuridine; Dactinomycin; Immune Tolerance; Immunosuppressive Agents; Lymph Nodes; Mercaptopurine; Metabolism; Mice; Nucleosides; Pharmacology; Research; Skin Transplantation; Spleen; Thioguanine; Transplantation Immunology; Transplantation, Homologous | 1965 |
INHIBITION OF PRUINE PHOSPHORIBOSYLTRANSFERASES OF EHRLICH ASCITES-TUMOUR CELLS BY 6-MERCAPTOPURINE.
Topics: Adenine; Adenine Nucleotides; Adenosine Monophosphate; Animals; Ascites; Carcinoma, Ehrlich Tumor; Diphosphates; Electrophoresis; Enzyme Inhibitors; Glucosyltransferases; Guanine; Guanine Nucleotides; Hypoxanthines; Kinetics; Mercaptopurine; Nucleotides; Pharmacology; Purines; Research; Spectrophotometry; Transferases; Xanthines | 1965 |
INHIBITION BY 6-MERCAPTOPURINE OF PURINE PHOSPHORIBOSYLTRANSFERASES FROM EHRLICH ASCITES-TUMOUR CELLS THAT ARE RESISTANT TO THE DRUG.
Topics: Adenine; Adenine Nucleotides; Animals; Ascites; Carcinoma, Ehrlich Tumor; Chromatography; Electrophoresis; Enzyme Inhibitors; Glucosyltransferases; Guanine; Guanine Nucleotides; Humans; Hypoxanthines; Ion Exchange Resins; Kinetics; Mercaptopurine; Metabolism; Nucleotides; Pentosyltransferases; Pharmacology; Research; Xanthines | 1965 |
INHIBITION OF FORMYLGLYCINAMIDE RIBONUCLEOTIDE SYNTHESIS IN NEOPLASTIC CELLS BY PURINES AND ANALOGS.
Topics: Adenine; Animals; Antimetabolites; Antineoplastic Agents; Azaserine; Carcinoma, Squamous Cell; Glycine; Hypoxanthines; Imidazoles; Leukemia L1210; Mercaptopurine; Nucleotides; Pharmacology; Purines; Research; Ribonucleotides; Thioguanine; Tissue Culture Techniques; Xanthines | 1965 |
The fidelity of replication of the three-base-pair set adenine/thymine, hypoxanthine/cytosine and 6-thiopurine/5-methyl-2-pyrimidinone with T7 DNA polymerase.
Topics: Adenine; Base Pairing; Cytosine; DNA Replication; DNA-Directed DNA Polymerase; Hypoxanthine; Kinetics; Mercaptopurine; Models, Genetic; Purines; Pyrimidinones; Research Design; Sensitivity and Specificity; Thymine | 2004 |
Preferential inhibition of xanthine oxidase by 2-amino-6-hydroxy-8-mercaptopurine and 2-amino-6-purine thiol.
Topics: Adenine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydroxylation; Kinetics; Mercaptopurine; Models, Chemical; Molecular Structure; Substrate Specificity; Thioguanine; Uric Acid; Xanthine; Xanthine Oxidase; Xanthines | 2007 |
6-mercaptopurine and 9-(2-phosphonyl-methoxyethyl) adenine (PMEA) transport altered by two missense mutations in the drug transporter gene ABCC4.
Topics: Adenine; Animals; Base Sequence; DNA Primers; Green Fluorescent Proteins; Humans; Mercaptopurine; Multidrug Resistance-Associated Proteins; Mutagenesis, Site-Directed; Mutation, Missense; Organophosphonates; Recombinant Fusion Proteins; Xenopus laevis | 2008 |
Down-regulation of Na+/H+ exchanger regulatory factor 1 increases expression and function of multidrug resistance protein 4.
Topics: Adenine; Antiviral Agents; Biological Transport; Cell Membrane; Down-Regulation; Fluorescent Antibody Technique, Indirect; Green Fluorescent Proteins; HeLa Cells; Humans; Immunoblotting; Immunoprecipitation; Immunosuppressive Agents; Kidney; Mercaptopurine; Multidrug Resistance-Associated Proteins; Organophosphonates; Phosphoproteins; Protein Transport; Recombinant Fusion Proteins; RNA, Small Interfering; Signal Transduction; Sodium-Hydrogen Exchangers; Transfection | 2008 |
Establishment of dsDNA/GNs/chit/GCE biosensor and electrochemical study on interaction between 6-mercaptopurine and DNA.
Topics: Adenine; Adsorption; Biosensing Techniques; Chitosan; DNA; DNA Damage; Drug Monitoring; Electric Impedance; Electrochemistry; Electrodes; Graphite; Guanine; Humans; Mercaptopurine; Oxidation-Reduction; Oxygen | 2014 |