adenine and mercaptopurine

adenine has been researched along with mercaptopurine in 79 studies

Research

Studies (79)

TimeframeStudies, this research(%)All Research%
pre-199068 (86.08)18.7374
1990's3 (3.80)18.2507
2000's6 (7.59)29.6817
2010's2 (2.53)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Seegmiller, JE; Shreier, MH; Waldmann, TA; Watanabe, T1
Agris, PF; Tompson, JG1
Dusanic, DG1
Gabrielsen, AE; Meuwissen, HJ; Moore, JJ; Pickering, RJ; Pollara, B1
Chenon, MT; Grant, DM; Panzica, RP; Pugmire, RJ; Townsend, LB2
Akiyama, Y; Hashimoto, H; Kitoh, T; Kubota, M; Mikawa, H; Shimizu, T; Takimoto, T1
Brajter-Toth, A; Volk, KJ; Yost, RA1
Ribeiro, LP1
Krepelka, J; Melka, M; Miko, M1
Kummer, D1
Hewson, K; Montgomery, JA1
Brown, GB; Sugiura, K1
Loeffler, JE; Mason, MI; Van Overbeek, J1
Coonrod, JD; Eickhoff, TC1
Holmes, EW; Kelley, WN; Pehlke, DM1
Flosdorf, J; Marutzky, R; Peterssen-Borstel, H1
Jezewska, MM1
Moiseenko, EV; Shust, AI; Tolstykh, LY1
Königk, E; Walter, RD1
Rosman, M; Williams, HE1
Creasey, WA; Lee, MH; Rosman, M; Sartorelli, AC1
Wilmanns, W1
Pickering, WR; Woods, RA1
Murphy, AJ1
Caldwell, IC; Chan, MC; Henderson, JF; Lau, KF; Paterson, AR; Paul, B1
Bragonier, JR; Carver, MJ1
Chirvasie, R; Dincă, A; Păuşescu, E1
Doctor, VM1
Benke, PJ; Herrick, N1
Mendonça, LC; Travassos, LR1
Chao, DL; Kimball, AP1
Sims, L1
Aaron, JJ; Winefordner, JD1
Davidson, JD1
Caldwell, IC1
Brown, GB; Parham, JC; Sugiura, K; Teller, MN1
Allan, PW; Hill, DL; Straight, S1
Hill, DL1
Blair, DG; Cross, DC; Peesker, SJ1
Oriuchi, T1
Brockman, RW; Dixon, GJ; Dulmadge, EA; Shaddix, SC1
Caldwell, IC; Henderson, JF; Kelley, WN; Rosenbloom, FM; Seegmiller, JE1
Henderson, JF; Kelly, WN; Rosenbloom, FM; Seegmiller, JE1
Kano, A1
St Geme, JW1
Cook, JM; Franklin, TJ1
Cruz, FS; Moreira, Mdo C; Travassos, LR1
Burchenal, JH; Butterbaugh, J; Dollinger, M; Giner-Sorolla, A; Stoll, D1
Baker, BR; Erickson, EH1
Al-Safi, SA; Maddocks, JL1
Gordon, PB; Seglen, PO1
Inui, N; Sato, S; Takizawa, H1
Bökkerink, JP; De Abreu, RA; Keizer-Garritsen, JJ; Lambooy, LH; Stet, EH; Trijbels, FJ; Vogels-Mentink, TM1
Innocenti, F; Iyer, L; Ratain, MJ1
LAW, LW1
FJELDE, A1
BALIS, ME; PECORA, P; SALSER, JS1
JEFFREY, JJ; SCHANKER, LS; TOCCO, DJ1
KALYANKAR, GD; MANSOOR, M; TALWAR, GP1
MAGASANIK, B; ZIMMERMAN, EF1
KARNOFSKY, DA; SIMMEL, EB1
BRAGONIER, JR; CARVER, MJ; ROESKY, N1
BIEBER, AL; BOOTH, BA; SARTORELLI, AC; UPCHURCH, HF1
BRINDLE, SD; HIRSCHBERG, E; SEMENTE, G1
LEVY, RN; RUOHANI, J; SAWITSKY, A1
GUTHRIE, R; LU, WC1
JUNGA, IG; LEPAGE, GA1
HOEHN, RJ1
ATKINSON, MR; MURRAY, AW2
BROCKMAN, RW; CHUMLEY, S1
Rappaport, HP1
Jena, G; Kalra, S; Mukhopadhyay, AK; Tikoo, K1
Closs, EI; Fischer, C; Fritz, P; Fromm, MF; Gödtel-Armbrust, U; Gradhand, U; Habermeier, A; Janke, D; Lang, T; Mehralivand, S; Nürnberg, P; Schwab, M; Strand, D; Toliat, MR; Wojnowski, L; Zanger, UM1
Cole, SP; Hoque, MT1
Tang, W; Zeng, X; Zhang, M1

Reviews

4 review(s) available for adenine and mercaptopurine

ArticleYear
Immunological aspects of purine metabolism.
    Advances in experimental medicine and biology, 1977, Volume: 76A

    Topics: Adenine; Adenosine; Adenosine Deaminase; Antibody Formation; Hormones; Humans; Immunity, Cellular; Immunologic Deficiency Syndromes; Immunosuppression Therapy; Inosine; Lesch-Nyhan Syndrome; Liver; Lymphocyte Activation; Lymphocytes; Mercaptopurine; Models, Biological; Nucleoside Deaminases; Pentosyltransferases; Purine-Nucleoside Phosphorylase; Purines; Synaptic Transmission; Uridine

1977
Immunosuppression and ablastin.
    Experimental parasitology, 1975, Volume: 38, Issue:3

    Topics: Adenine; Animals; Antibodies; Antibody Formation; Antilymphocyte Serum; Cyclophosphamide; Dexamethasone; DNA; Female; Immunosuppression Therapy; Male; Mercaptopurine; Mice; Mononuclear Phagocyte System; Pregnancy; Rats; Reproduction; Sodium Salicylate; Spleen; T-Lymphocytes; Thymus Gland; Trypanosoma; Trypanosomiasis

1975
Pharmacogenetics: a tool for individualizing antineoplastic therapy.
    Clinical pharmacokinetics, 2000, Volume: 39, Issue:5

    Topics: Adenine; Antineoplastic Agents; Camptothecin; Dihydrouracil Dehydrogenase (NADP); Fluorouracil; Genotype; Glucuronosyltransferase; Humans; Imides; Irinotecan; Isoquinolines; Mercaptopurine; Methyltransferases; Naphthalimides; Organophosphonates; Oxidoreductases; Pharmacogenetics; Phenotype

2000
EFFECTS OF GROWTH-INHIBITING CHEMICALS ON THE SAND-DOLLAR EMBRYO, ECHINARACHNIUS PARMA.
    Progress in experimental tumor research, 1963, Volume: 3

    Topics: Adenine; Animals; Azaguanine; Bromodeoxyuridine; Colchicine; Dinitrophenols; Echinodermata; Embryo, Mammalian; Embryo, Nonmammalian; Enzyme Inhibitors; Floxuridine; Fluorouracil; Growth; Idoxuridine; Mercaptopurine; Pharmacology; Pyrimidines; Sea Urchins

1963

Other Studies

75 other study(ies) available for adenine and mercaptopurine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Production of specific site probes of tRNA structure by enrichment with carbon 13 at particular locations.
    Nucleic acids research, 1979, Oct-10, Volume: 7, Issue:3

    Topics: Adenine; Carbon Isotopes; Escherichia coli; Isotope Labeling; Kinetics; Magnetic Resonance Spectroscopy; Mercaptopurine; Methionine; Molecular Conformation; Nucleic Acid Conformation; Purines; RNA, Transfer; Uracil

1979
Combined immunodeficiency disease: an inborn error of purine metabolism.
    Birth defects original article series, 1975, Volume: 11, Issue:1

    Topics: Adenine; Adenosine Deaminase; Chromosomes, Human, 19-20; Enzyme Inhibitors; Erythrocytes; Humans; Immunogenetics; Immunologic Deficiency Syndromes; Inosine; Isoenzymes; Lesch-Nyhan Syndrome; Liver; Lung; Lymphocytes; Mercaptopurine; Molecular Weight; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Tissue Extracts

1975
Carbon-13 magnetic resonance. XXV. A basic set of parameters for the investigation of tautomerism im purines. Established from carbon-13 magnetic resonance studies using certain purines and pyrrolo[2,3-d]pyrimidines.
    Journal of the American Chemical Society, 1975, Aug-06, Volume: 97, Issue:16

    Topics: Adenine; Hypoxanthines; Magnetic Resonance Spectroscopy; Mercaptopurine; Purines; Pyrimidines; Pyrroles

1975
Carbon-13 magnetic resonance. XXVI. A quantitative determination of the tautomeric populations of certain purines.
    Journal of the American Chemical Society, 1975, Aug-06, Volume: 97, Issue:16

    Topics: Adenine; Hypoxanthines; Isomerism; Magnetic Resonance Spectroscopy; Mercaptopurine; Purines

1975
Biochemical basis of the prevention of 6-thiopurine toxicity by the nucleobases, hypoxanthine and adenine.
    Leukemia research, 1990, Volume: 14, Issue:11-12

    Topics: 2-Aminopurine; Adenine; Adenine Phosphoribosyltransferase; Antineoplastic Agents; Biological Transport; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Inosine Monophosphate; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Promyelocytic, Acute; Mercaptopurine; Thioguanine; Thionucleotides; Tumor Cells, Cultured

1990
Characterization of solution-phase and gas-phase reactions in on-line electrochemistry-thermospray tandem mass spectrometry.
    Journal of chromatography, 1989, Jul-14, Volume: 474, Issue:1

    Topics: Adenine; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Electrochemistry; Gases; Hypoxanthine; Hypoxanthines; Mass Spectrometry; Mercaptopurine; Purines; Solutions

1989
Inhibition of xanthine dehydrogenase from Triatoma infestans by some purine analogues.
    Biomedica biochimica acta, 1988, Volume: 47, Issue:2

    Topics: Adenine; Animals; Disease Vectors; Ketone Oxidoreductases; Mercaptopurine; Purines; Triatoma; Triatominae; Trypanosoma cruzi; Xanthine Dehydrogenase; Xanthines

1988
Inhibition of biosynthetic processes in P388 and Ehrlich ascites cells by cloturin.
    Drugs under experimental and clinical research, 1988, Volume: 14, Issue:9

    Topics: Adenine; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; DNA, Neoplasm; Kinetics; Leukemia P388; Mercaptopurine; Mice; Mustard Compounds; Neoplasm Proteins; Neoplasms, Experimental; RNA, Neoplasm; Thymidine; Tumor Cells, Cultured; Uridine

1988
[Effects of cytostatics and x-rays on nucleic acid metabolism of solid, malignant tumors in vitro].
    Zeitschrift fur Krebsforschung, 1970, Volume: 74, Issue:1

    Topics: Adenine; Animals; Antineoplastic Agents; Carbon Isotopes; Dactinomycin; Depression, Chemical; DNA, Neoplasm; Estriol; Fluorouracil; Formates; Glycine; Hypoxanthines; In Vitro Techniques; Leucine; Mercaptopurine; Methotrexate; Methylprednisolone; Neoplasm Proteins; Neoplasms, Experimental; Nucleosides; Orotic Acid; Radiation Effects; RNA, Neoplasm; Testosterone; Thymidine; Triaziquone; Uracil; Uridine

1970
Nucleosides from homoribose.
    Journal of medicinal chemistry, 1966, Volume: 9, Issue:2

    Topics: Adenine; Chemical Phenomena; Chemistry; Chemistry, Organic; Electron Spin Resonance Spectroscopy; Mercaptopurine; Nucleosides; Organic Chemistry Phenomena; Purines

1966
Purine N-oxides. XIX. On the oncogenic N-oxide derivatives of guanine and xanthine and a nononcogenic isomer of xanthine N-oxide.
    Cancer research, 1967, Volume: 27, Issue:5

    Topics: Adenine; Animals; Carcinoma, Hepatocellular; Guanine; Liver Neoplasms; Mercaptopurine; Neoplasms; Neoplasms, Experimental; Oxides; Rats; Xanthines

1967
Dormin (Abscisin II), inhibitor of plant DNA synthesis?
    Science (New York, N.Y.), 1967, Jun-16, Volume: 156, Issue:3781

    Topics: Adenine; Antimetabolites; Benzene Derivatives; Culture Techniques; Depression, Chemical; DNA; Mercaptopurine; Phosphorus Isotopes; Plant Growth Regulators; Plants; Ribosomes; RNA; Silicon Dioxide

1967
Combined action of 6-mercaptopurine and antibiotics on gram-negative bacteria in vitro.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1972, Volume: 140, Issue:2

    Topics: Adenine; Ampicillin; Anti-Bacterial Agents; Cephalothin; Chloramphenicol; Culture Media; Drug Synergism; Enterobacteriaceae; Escherichia coli; Gentamicins; Hypoxanthines; Kanamycin; Klebsiella; Mercaptopurine; Penicillin Resistance; Polymyxins; Pseudomonas; Streptomycin; Tetracycline; Time Factors; Xanthines

1972
Human IMP dehydrogenase. Kinetics and regulatory properties.
    Biochimica et biophysica acta, 1974, Oct-17, Volume: 364, Issue:2

    Topics: Adenine; Adenosine; Carbon Radioisotopes; Cell Fractionation; Chromatography, DEAE-Cellulose; Chromatography, Paper; Cytosol; Female; Guanine; Guanosine; Humans; Inosine Nucleotides; Ketone Oxidoreductases; Kinetics; Mercaptopurine; Mitochondria; NAD; Placenta; Pregnancy; Purine Nucleotides; Pyrimidine Nucleotides; Structure-Activity Relationship; Ultracentrifugation

1974
Large scale enzymatic synthesis of nucleoside-5'-monophosphates using a phosphotransferase from carrots.
    Biotechnology and bioengineering, 1974, Volume: 16, Issue:11

    Topics: Adenine; Aza Compounds; Chromatography, DEAE-Cellulose; Chromatography, Gel; Deoxyadenosines; Mercaptopurine; Nitrophenols; Nucleosides; Nucleotides; Oxidative Phosphorylation; Phosphates; Phosphoric Monoester Hydrolases; Phosphotransferases; Plants, Edible; Purine Nucleosides; Pyrimidines; Pyrroles; Ribonucleosides; Vegetables

1974
Effect of allopurinol (4-hydroxyprazolo(3,4-d)pyrimidine) on xanthine accumulation by milk xanthine oxidase in vitro.
    European journal of biochemistry, 1974, Jul-15, Volume: 46, Issue:2

    Topics: Adenine; Allopurinol; Animals; Antimetabolites; Aza Compounds; Azaguanine; Hypoxanthines; In Vitro Techniques; Mercaptopurine; Milk; Oxidoreductases; Purines; Spectrophotometry; Uric Acid; Xanthine Oxidase; Xanthines

1974
Characteristics of mutant clones of Chinese hamster cells resistant to purine analogues.
    Soviet genetics, 1974, Dec-01, Volume: 9, Issue:2

    Topics: Adenine; Animals; Azaguanine; Carbon Radioisotopes; Cell Division; Cell Survival; Clone Cells; Cricetinae; Drug Resistance; Hydrogen-Ion Concentration; Hypoxanthines; Mercaptopurine; Mutation; Pentosyltransferases; Phenotype

1974
Hypoxanthine-guanine phosphoribosyltransferase and adenine phosphoribosyltransferase from Plasmodium chabaudi, purification and properties.
    Tropenmedizin und Parasitologie, 1974, Volume: 25, Issue:2

    Topics: Adenine; Guanine; Hypoxanthines; Isoelectric Focusing; Isoenzymes; Mercaptopurine; Molecular Weight; Pentosyltransferases; Plasmodium; Thioguanine

1974
Leukocyte purine phosphoribosyltransferases in human leukemias sensitive and resistant to 6-thiopurines.
    Cancer research, 1973, Volume: 33, Issue:6

    Topics: Adenine; Adolescent; Adult; Aged; Antimetabolites; Drug Resistance; Female; Guanine; Humans; Hypoxanthines; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Male; Mercaptopurine; Mutation; Pentosyltransferases; Remission, Spontaneous; Thioguanine

1973
Mechanisms of resistance to 6-thiopurines in human leukemia.
    Cancer research, 1974, Volume: 34, Issue:8

    Topics: Adenine; Alkaline Phosphatase; Drug Resistance; Guanine; Humans; Hypoxanthines; Leukemia; Leukemia, Lymphoid; Lymphocytes; Mercaptopurine; Pentosyltransferases; Thioguanine

1974
Synthesis of purine nucleotides in human and leukemic cells. Interaction of 6-mercaptopurine and allopurinol.
    Advances in experimental medicine and biology, 1973, Volume: 41

    Topics: Adenine; Allopurinol; Bone Marrow; Bone Marrow Cells; Carbon Radioisotopes; Cell-Free System; Chromatography, Paper; Formates; Guanine Nucleotides; Humans; Hypoxanthines; Kinetics; Leucovorin; Leukemia; Leukemia, Myeloid, Acute; Leukocytes; Ligases; Mercaptopurine; Pentosephosphates; Pentosyltransferases; Spectrophotometry, Ultraviolet; Tetrahydrofolates

1973
Genetics of resistance to 4-aminopyrazolo-(3,4-d)-pyrimidine in Saccharomyces cerevisiae.
    Molecular & general genetics : MGG, 1973, May-09, Volume: 122, Issue:3

    Topics: Adenine; Aza Compounds; Chromosome Mapping; Crosses, Genetic; Drug Resistance, Microbial; Genes, Dominant; Genes, Recessive; Genetic Linkage; Genetics, Microbial; Guanine; Hypoxanthines; Mercaptopurine; Methylation; Purines; Pyrazoles; Pyrimidines; Saccharomyces cerevisiae; Suppression, Genetic

1973
Circular dichroism of the adenine and 6-mercaptopurine nucleotide complexes of heavy meromyosin.
    Archives of biochemistry and biophysics, 1974, Volume: 163, Issue:1

    Topics: Adenine; Animals; Binding Sites; Circular Dichroism; Mathematics; Mercaptopurine; Molecular Weight; Myosin Subfragments; Myosins; Protein Binding; Protein Conformation; Rabbits; Spectrophotometry, Ultraviolet

1974
Inhibitors of nucleoside and nucleotide metabolism.
    Cancer chemotherapy reports. Part 2, 1972, Volume: 3, Issue:1

    Topics: Adenine; Adenine Nucleotides; Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Erythrocytes; Guanine; Humans; Hypoxanthines; Mercaptopurine; Neoplasms; Nucleosides; Nucleotides; Pentosyltransferases; Phosphotransferases; Purines; Pyrimidines; Thioguanine

1972
The influence of 6-mercaptopurine on rat placenta and fetus.
    Biochemical pharmacology, 1968, Volume: 17, Issue:8

    Topics: Abnormalities, Drug-Induced; Adenine; Animals; Chromatography; DNA; Female; Fetus; Glycine; Guanine; Mercaptopurine; Placenta; Pregnancy; Pregnancy, Animal; Rats; RNA; Spinal Dysraphism; Spine

1968
[On the effects of immunosuppressive and cytostatic substances on the oxidative metabolism of leukocytes during the rejection of kidney homotransplants].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1968, Jan-15, Volume: 23, Issue:2

    Topics: Adenine; Animals; Antigen-Antibody Reactions; Antineoplastic Agents; Citric Acid Cycle; Cyclophosphamide; Dogs; Immunosuppressive Agents; In Vitro Techniques; Ketoglutaric Acids; Kidney Transplantation; Leukocytes; Mercaptopurine; Oxidation-Reduction; Succinates; Time Factors; Transplantation Immunology; Transplantation, Homologous; Triaziquone

1968
Inhibition of methotrexate resistant mutant of Streptococcus faecalis by analogs of purine and pyrimidine.
    Chemotherapy, 1970, Volume: 15, Issue:1

    Topics: Adenine; Adenine Nucleotides; Azaguanine; Drug Resistance, Microbial; Enterococcus faecalis; Guanine; Kinetics; Mercaptopurine; Methotrexate; Mutation; Nucleosides; Purines; Pyrimidines; Thioguanine; Thymine

1970
Azaguanine-resistance as a manifestation of a new form of metabolic overproduction of uric acid.
    The American journal of medicine, 1972, Volume: 52, Issue:4

    Topics: Adenine; Adolescent; Aminopterin; Azaguanine; Blood Urea Nitrogen; Carbon Isotopes; Cell Line; Creatinine; Drug Resistance; Electrophoresis, Starch Gel; Erythrocytes; Fibroblasts; Gout; Guanine; Humans; Hypoxanthines; Lesch-Nyhan Syndrome; Male; Mercaptopurine; Pentosyltransferases; Purines; Uric Acid

1972
Metabolism of ethionine in ethionine-sensitive and ethionine-resistant cells of the enteric yeast Candida slooffii.
    Journal of bacteriology, 1972, Volume: 110, Issue:2

    Topics: Adenine; Amino Acids; Candida; Carbon Isotopes; Cell Fractionation; Choline; Chromatography, Paper; Culture Media; Depression, Chemical; Drug Resistance, Microbial; Ethionine; Genetics, Microbial; Mercaptopurine; Methionine; Mutation; Phenylalanine; Purines; Pyrimidines; Stereoisomerism; Tritium

1972
Deamination of arabinosyladenine by adenosine deaminase and inhibition by arabinosyl-6-mercaptopurine.
    Cancer research, 1972, Volume: 32, Issue:8

    Topics: Adenine; Adenosine; Aminohydrolases; Animals; Antibiotics, Antineoplastic; Arabinose; Cell Fractionation; Cell Line; Deamination; Drug Resistance; Female; Leukemia L1210; Mercaptopurine; Mice; Mice, Inbred Strains; Mutation; Nucleosides

1972
Drugs used in radiotherapy.
    Radiography, 1972, Volume: 38, Issue:448

    Topics: Adenine; Alkylating Agents; Analgesics; Anemia; Anti-Bacterial Agents; Antiemetics; Antimetabolites; Antineoplastic Agents; Drug Therapy; Expectorants; Folic Acid; Humans; Mercaptopurine; Methotrexate; Neoplasms; Pharmaceutical Preparations; Radiotherapy; Steroids; Tranquilizing Agents; Vitamins

1972
Analytical study of the phosphorescence of purines in aqueous solution at 77 degrees K.
    Analytical chemistry, 1972, Volume: 44, Issue:13

    Topics: Adenine; Fluorescence; Hydrogen-Ion Concentration; Mercaptopurine; Purines; Spectrometry, Fluorescence; Temperature; Water

1972
Formal discussion on resistance to purine antagonists in experimental leukemia systems.
    Cancer research, 1965, Volume: 25, Issue:9

    Topics: Adenine; Animals; Guanine; Humans; Hypoxanthines; In Vitro Techniques; Leukemia, Lymphoid; Leukemia, Myeloid; Mercaptopurine; Mice; Nucleotidyltransferases

1965
Ion-exchange chromatography of tissue nucleotides.
    Journal of chromatography, 1969, Oct-28, Volume: 44, Issue:2

    Topics: Adenine; Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Chromatography, Ion Exchange; Guanine; Liver; Mercaptopurine; Mice; Nucleosides; Nucleotides; Spectrophotometry; Tissue Extracts

1969
A comparison of the oncogenicities of 3-hydroxyxanthine, guanine 3-N-oxide, and some related compounds.
    Cancer research, 1970, Volume: 30, Issue:1

    Topics: Adenine; Animals; Chemical Phenomena; Chemistry; Female; Granuloma; Guanine; Injections, Subcutaneous; Liver Neoplasms; Male; Mercaptopurine; Neoplasms, Experimental; Oxides; Purines; Rats; Xanthines

1970
Use of Tetrahymena pyriformis to evaluate the effects of purine and pyrimidine analogs.
    The Journal of protozoology, 1970, Volume: 17, Issue:4

    Topics: Adenine; Animals; Antimetabolites; Culture Media; Mercaptopurine; Nucleosides; Purines; Pyrimidines; Tetrahymena; Thioguanine

1970
Hypoxanthine phosphoribosyltransferase and guanine metabolism of adenocarcinoma 755 cells.
    Biochemical pharmacology, 1970, Volume: 19, Issue:2

    Topics: Adenine; Adenocarcinoma; Buffers; Carbon Isotopes; Guanine; Hydrogen-Ion Concentration; Hypoxanthines; In Vitro Techniques; Kinetics; Mercaptopurine; Neoplasms, Experimental; Nucleotides; Purines; Thioguanine; Transferases

1970
The toxicity of adenine and of purine-analogs to 2,6-diamino-purine-sensitive and -resistant L-strain mouse cells.
    Canadian journal of microbiology, 1970, Volume: 16, Issue:8

    Topics: Adenine; Albumins; Amino Acids; Aminobenzoates; Animals; Culture Media; Hypoxanthines; Imidazoles; L Cells; Mercaptopurine; Mice; Nucleosides; Pantothenic Acid; Purines; Pyrimidines; Thiamine; Thioguanine; Triazoles

1970
[On uptake of 5-FU, 6-MP and methotrexate by ehrlich ascites tumor cells in vitro].
    Sapporo igaku zasshi. The Sapporo medical journal, 1970, Volume: 37, Issue:6

    Topics: Adenine; Animals; Carcinoma, Ehrlich Tumor; Cell Membrane; Fluorouracil; In Vitro Techniques; Male; Mercaptopurine; Methotrexate; Mice; Sulfur Isotopes; Time Factors; Tritium; Uracil

1970
Feedback inhibition of purine biosynthesis in adenocarcinoma 755 and sarcoma 180 cells in culture.
    Journal of the National Cancer Institute, 1970, Volume: 45, Issue:4

    Topics: Adenine; Adenocarcinoma; Animals; Azaserine; Carbon Isotopes; Cell Line; Feedback; Hypoxanthines; Mercaptopurine; Methotrexate; Neoplasms, Experimental; Nucleotides; Phosphotransferases; Purines; Sarcoma 180; Thioguanine

1970
Biochemical bases of accelerated purine biosynthesis de novo in human fibroblasts lacking hypoxanthine-guanine phosphoribosyltransferase.
    The Journal of biological chemistry, 1968, Mar-25, Volume: 243, Issue:6

    Topics: Adenine; Adenine Nucleotides; Adolescent; Adult; Athetosis; Biopsy; Carbon Isotopes; Child; Child, Preschool; Chorea; Chromatography, Gel; Culture Techniques; Feedback; Female; Fibroblasts; Formates; Guanine; Guanine Nucleotides; Humans; Hypoxanthines; Intellectual Disability; Male; Mercaptopurine; Nucleotides; Purines; Self Mutilation; Spasm; Transferases; Tritium

1968
Accelerated purine biosynthesis de novo in skin fibroblasts deficient in hypoxanthine--guanine phosphoribosyltransferase activity.
    Biochimica et biophysica acta, 1968, Aug-23, Volume: 166, Issue:1

    Topics: Adenine; Adenine Nucleotides; Carbon Isotopes; Depression, Chemical; Erythrocytes; Feedback; Fibroblasts; Formates; Guanine; Humans; Hypoxanthines; Mercaptopurine; Metabolic Diseases; Nucleosides; Purines; Skin; Stimulation, Chemical; Transferases; Tritium

1968
[Nucleic acid metabolism of leukemic leukocytes. 2. The effect of 6-mercaptopurine on nucleic acid metabolism of leukemic leukocytes].
    Naika hokan. Japanese archives of internal medicine, 1968, Volume: 15, Issue:8

    Topics: Adenine; Carbon Isotopes; Guanine; Humans; Hypoxanthines; Leukemia; Leukocytes; Mercaptopurine; Nucleic Acids; Purines

1968
The action of 6-mercaptopurine in human heteroploid cells.
    Biochimica et biophysica acta, 1969, Mar-18, Volume: 179, Issue:1

    Topics: Adenine; Antiviral Agents; Biological Assay; Culture Techniques; Hypoxanthines; Imidazoles; Imides; Mercaptopurine; Nucleosides; Vaccinia virus

1969
The inhibition of nucleic acid synthesis by mycophenolic acid.
    The Biochemical journal, 1969, Volume: 113, Issue:3

    Topics: Adenine; Animals; Antibiotics, Antineoplastic; Caproates; DNA, Neoplasm; Guanine; Guanine Nucleotides; Hypoxanthines; In Vitro Techniques; L Cells; Mercaptopurine; Mice; Neoplasms, Experimental; Oxidoreductases; Rats; Sarcoma, Yoshida; Thymidine

1969
[Action of ethylic urethane on the growth of Candida slooffii].
    Anais de microbiologia, 1965, Volume: 13

    Topics: Adenine; Amino Acids; Candida; Mercaptopurine; Urethane

1965
Studies of 6-N-hydroxylamino-9-beta-D-ribofuranosylpurine in mouse leukemia.
    Biochemical pharmacology, 1967, Volume: 16, Issue:3

    Topics: Adenine; Animals; Body Weight; Cytarabine; Drug Antagonism; Drug Synergism; Fluorouracil; Guanine; Leukemia; Leukemia L1210; Mercaptopurine; Methotrexate; Mice; Nucleosides; Phosphotransferases; Purines; Vincristine

1967
Irreversible enzyme inhibitors. 98. Hydrophobic interactions with succinoadenylate kinosynthetase and 9-substituted adenines.
    Journal of pharmaceutical sciences, 1967, Volume: 56, Issue:9

    Topics: Adenine; Chemical Phenomena; Chemistry; Ligases; Mercaptopurine

1967
Azathioprine and 6-mercaptopurine (6-MP) suppress the human mixed lymphocyte reaction (MLR) by different mechanisms.
    British journal of clinical pharmacology, 1984, Volume: 17, Issue:4

    Topics: Adenine; Adenosine; Aminoimidazole Carboxamide; Azathioprine; DNA; Guanine; Humans; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Lymphocyte Culture Test, Mixed; Lymphocytes; Mercaptopurine; Xanthine; Xanthines

1984
6-substituted purines: a novel class of inhibitors of endogenous protein degradation in isolated rat hepatocytes.
    Archives of biochemistry and biophysics, 1982, Volume: 217, Issue:1

    Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Liver; Lysosomes; Male; Mercaptopurine; Proteins; Purines; Puromycin Aminonucleoside; Rats; Rats, Inbred Strains

1982
Mouse strain differences in induction of micronuclei by base analogues and nucleosides.
    Mutation research, 1993, Volume: 301, Issue:1

    Topics: Adenine; Animals; Bromodeoxyuridine; Bromouracil; Cytarabine; Erythrocytes; Female; Floxuridine; Guanosine; Mercaptopurine; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Micronucleus Tests; Mitogens; Nucleosides; Purines; Pyrimidines; Species Specificity; Thymidine; Uridine

1993
Reversal of methylmercaptopurine ribonucleoside cytotoxicity by purine ribonucleosides and adenine.
    Biochemical pharmacology, 1995, Jan-06, Volume: 49, Issue:1

    Topics: Adenine; Adenosine; Antineoplastic Agents; Cell Division; Cell Survival; Cells, Cultured; Guanosine; Humans; Inosine; Mercaptopurine; Methylthioinosine; Nucleosides; Nucleotides; Purine Nucleosides; Ribonucleosides; T-Lymphocytes; Thioinosine; Thionucleotides

1995
Resistance in leukemic cells to an adenine antagonist, 6-mercaptopurine.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1953, Volume: 84, Issue:2

    Topics: Adenine; Animals; Humans; Leukemia, Experimental; Mercaptopurine; Purines

1953
The effect of two purine analogs on a human tumor in tissue culture.
    Zeitschrift fur Krebsforschung, 1956, Volume: 61, Issue:4

    Topics: Adenine; Animals; Antimetabolites; Carcinoma; Carcinoma, Squamous Cell; Humans; Mercaptopurine; Neoplasms; Neoplasms, Experimental

1956
STUDIES OF COMPOUNDS THAT INHIBIT CELL GROWTH.
    Experimental cell research, 1963, Volume: 24

    Topics: Acridines; Adenine; Animals; Carcinoma; Carcinoma, Ehrlich Tumor; DNA; DNA, Neoplasm; Guanine; Liver; Mercaptopurine; Mice; Neoplasms; Nucleotides; Pharmacology; Proteins; Research

1963
INTERACTION OF PURINES WITH THE PYRIMIDINE TRANSPORT PROCESS OF THE SMALL INTESTINE.
    Biochemical pharmacology, 1963, Volume: 12

    Topics: Adenine; Caffeine; Carbon Isotopes; Guanine; Intestine, Small; Intestines; Mercaptopurine; Pharmacology; Physiology; Purines; Pyrimidines; Rats; Research; Theobromine; Theophylline; Uracil; Uric Acid; Xanthines

1963
BRAIN GUANINE DEAMINASE: PURIFICATION, PROPERTIES AND REGIONAL DISTRIBUTION.
    Biochimica et biophysica acta, 1963, Oct-01, Volume: 77

    Topics: Adenine; Adenine Nucleotides; Aminohydrolases; Animals; Brain; Cerebral Cortex; Guanine; Guanine Deaminase; Guanine Nucleotides; Haplorhini; Hydrogen-Ion Concentration; Mercaptopurine; Nucleosides; Rats; Research; Sheep; Spectrum Analysis; Thalamus

1963
UTILIZATION AND INTERCONVERSION OF PURINE BASES AND RIBONUCLEOSIDES BY SALMONELLA TYPHIMURIUM.
    The Journal of biological chemistry, 1964, Volume: 239

    Topics: Adenine; Adenine Nucleotides; Carbon Isotopes; Chromatography; Culture Media; Guanine; Guanine Nucleotides; Histidine; Mercaptopurine; Metabolism; Nucleosides; Purines; Research; Ribonucleosides; Salmonella typhimurium; Spectrophotometry

1964
TERATOGENESIS: EFFECTS OF SUBSTITUTED PURINES AND THE INFLUENCE OF 4-HYDROXYPYRAZOLOPYRIMIDINE IN THE RAT.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1964, Volume: 116

    Topics: Abnormalities, Drug-Induced; Adenine; Female; Mercaptopurine; Neoplasms; Neoplasms, Experimental; Pharmacology; Placenta; Pregnancy; Purines; Pyrazoles; Pyrimidines; Rats; Research; Teratogenesis; Thioguanine; Toxicology

1964
SOME METABOLIC EFFECTS EXERTED BY AZASERINE AND PURINE ANALOGS IN VIVO.
    Cancer research, 1964, Volume: 24

    Topics: Adenine; Amino Acids; Animals; Antimetabolites; Antineoplastic Agents; Azaserine; Carbon Isotopes; Glycine; Guanine; Mercaptopurine; Metabolism; Mice; Neoplasm Transplantation; Nucleotides; Pharmacology; Purines; Research; Sarcoma 180

1964
DEVELOPMENT AND PROPERTIES OF MOUSE LEUKEMIA L1210 RESISTANT TO MIRACIL D.
    Cancer research, 1964, Volume: 24

    Topics: Adenine; Animals; Azaguanine; Cyclophosphamide; Enzyme Inhibitors; Folic Acid; Glutamates; Guanine; Leucovorin; Leukemia L1210; Lucanthone; Mercaptopurine; Methotrexate; Mice; Pharmacology; Proadifen; Pyridoxine; Research; Thioguanine

1964
DRUG FEVER PRODUCED BY SIX-MERCAPTOPURINE.
    Annals of internal medicine, 1964, Volume: 61

    Topics: Adenine; Antineoplastic Agents; Drug Therapy; Fever; Hematocrit; Leukemia; Leukocyte Count; Mercaptopurine; Purines; Thioguanine; Toxicology

1964
ANTAGONISM BETWEEN PURINES IN PURINE-REQUIRING BACILLUS SUBTILIS MUTANTS.
    Archives of biochemistry and biophysics, 1964, Volume: 108

    Topics: 2-Aminopurine; Adenine; Adenine Nucleotides; Azaguanine; Bacillus subtilis; Guanine; Guanine Nucleotides; Hypoxanthines; Mercaptopurine; Metabolism; Mutation; Nucleosides; Nucleotides; Pharmacology; Purines; Research; Xanthines

1964
METABOLISM OF PURINE NUCLEOSIDE ANALOGS.
    Cancer research, 1965, Volume: 25

    Topics: Adenine; Animals; Antimetabolites; Guanine; Mercaptopurine; Metabolism; Mice; Neoplasms; Neoplasms, Experimental; Nucleosides; Purine Nucleosides; Purines; Research

1965
INDUCTION OF TOLERANCE TO MOUSE TAIL SKIN HOMOGRAFTS BY COMBINING PAIRED IMMUNOSUPPRESSIVE AGENTS AND CELLULAR ANTIGENS.
    Transplantation, 1965, Volume: 3

    Topics: Adenine; Allografts; Animals; Antigens; Azathioprine; Bromodeoxyuridine; Dactinomycin; Immune Tolerance; Immunosuppressive Agents; Lymph Nodes; Mercaptopurine; Metabolism; Mice; Nucleosides; Pharmacology; Research; Skin Transplantation; Spleen; Thioguanine; Transplantation Immunology; Transplantation, Homologous

1965
INHIBITION OF PRUINE PHOSPHORIBOSYLTRANSFERASES OF EHRLICH ASCITES-TUMOUR CELLS BY 6-MERCAPTOPURINE.
    The Biochemical journal, 1965, Volume: 94

    Topics: Adenine; Adenine Nucleotides; Adenosine Monophosphate; Animals; Ascites; Carcinoma, Ehrlich Tumor; Diphosphates; Electrophoresis; Enzyme Inhibitors; Glucosyltransferases; Guanine; Guanine Nucleotides; Hypoxanthines; Kinetics; Mercaptopurine; Nucleotides; Pharmacology; Purines; Research; Spectrophotometry; Transferases; Xanthines

1965
INHIBITION BY 6-MERCAPTOPURINE OF PURINE PHOSPHORIBOSYLTRANSFERASES FROM EHRLICH ASCITES-TUMOUR CELLS THAT ARE RESISTANT TO THE DRUG.
    The Biochemical journal, 1965, Volume: 94

    Topics: Adenine; Adenine Nucleotides; Animals; Ascites; Carcinoma, Ehrlich Tumor; Chromatography; Electrophoresis; Enzyme Inhibitors; Glucosyltransferases; Guanine; Guanine Nucleotides; Humans; Hypoxanthines; Ion Exchange Resins; Kinetics; Mercaptopurine; Metabolism; Nucleotides; Pentosyltransferases; Pharmacology; Research; Xanthines

1965
INHIBITION OF FORMYLGLYCINAMIDE RIBONUCLEOTIDE SYNTHESIS IN NEOPLASTIC CELLS BY PURINES AND ANALOGS.
    Biochimica et biophysica acta, 1965, Mar-15, Volume: 95

    Topics: Adenine; Animals; Antimetabolites; Antineoplastic Agents; Azaserine; Carcinoma, Squamous Cell; Glycine; Hypoxanthines; Imidazoles; Leukemia L1210; Mercaptopurine; Nucleotides; Pharmacology; Purines; Research; Ribonucleotides; Thioguanine; Tissue Culture Techniques; Xanthines

1965
The fidelity of replication of the three-base-pair set adenine/thymine, hypoxanthine/cytosine and 6-thiopurine/5-methyl-2-pyrimidinone with T7 DNA polymerase.
    The Biochemical journal, 2004, Aug-01, Volume: 381, Issue:Pt 3

    Topics: Adenine; Base Pairing; Cytosine; DNA Replication; DNA-Directed DNA Polymerase; Hypoxanthine; Kinetics; Mercaptopurine; Models, Genetic; Purines; Pyrimidinones; Research Design; Sensitivity and Specificity; Thymine

2004
Preferential inhibition of xanthine oxidase by 2-amino-6-hydroxy-8-mercaptopurine and 2-amino-6-purine thiol.
    BMC biochemistry, 2007, May-18, Volume: 8

    Topics: Adenine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydroxylation; Kinetics; Mercaptopurine; Models, Chemical; Molecular Structure; Substrate Specificity; Thioguanine; Uric Acid; Xanthine; Xanthine Oxidase; Xanthines

2007
6-mercaptopurine and 9-(2-phosphonyl-methoxyethyl) adenine (PMEA) transport altered by two missense mutations in the drug transporter gene ABCC4.
    Human mutation, 2008, Volume: 29, Issue:5

    Topics: Adenine; Animals; Base Sequence; DNA Primers; Green Fluorescent Proteins; Humans; Mercaptopurine; Multidrug Resistance-Associated Proteins; Mutagenesis, Site-Directed; Mutation, Missense; Organophosphonates; Recombinant Fusion Proteins; Xenopus laevis

2008
Down-regulation of Na+/H+ exchanger regulatory factor 1 increases expression and function of multidrug resistance protein 4.
    Cancer research, 2008, Jun-15, Volume: 68, Issue:12

    Topics: Adenine; Antiviral Agents; Biological Transport; Cell Membrane; Down-Regulation; Fluorescent Antibody Technique, Indirect; Green Fluorescent Proteins; HeLa Cells; Humans; Immunoblotting; Immunoprecipitation; Immunosuppressive Agents; Kidney; Mercaptopurine; Multidrug Resistance-Associated Proteins; Organophosphonates; Phosphoproteins; Protein Transport; Recombinant Fusion Proteins; RNA, Small Interfering; Signal Transduction; Sodium-Hydrogen Exchangers; Transfection

2008
Establishment of dsDNA/GNs/chit/GCE biosensor and electrochemical study on interaction between 6-mercaptopurine and DNA.
    Bio-medical materials and engineering, 2014, Volume: 24, Issue:1

    Topics: Adenine; Adsorption; Biosensing Techniques; Chitosan; DNA; DNA Damage; Drug Monitoring; Electric Impedance; Electrochemistry; Electrodes; Graphite; Guanine; Humans; Mercaptopurine; Oxidation-Reduction; Oxygen

2014