Compounds > adenine

adenine and melphalan

adenine has been researched along with melphalan in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19902 (18.18)18.7374
1990's2 (18.18)18.2507
2000's2 (18.18)29.6817
2010's5 (45.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Karuzina, NP; Timofeevskaia, EA1
Lawley, PD; Osborne, MR1
Berry, DA; Cirrincione, C; Costanza, ME; Frei, E; Henderson, IC; McIntyre, OR; Norton, L; Schilsky, RL; Weiss, RB; Winer, E; Wood, WC1
COSTAKEL, O1
Balcome, S; Hafner, L; Park, S; Phillips, L; Quirk Dorr, DR; Tretyakova, N1
Chen, L; Chen, X; Dong, B; Dong, H; Gao, G; Gao, Y; Pan, Y; Yang, Y1
Baik, MH; Polavarapu, A; Stillabower, JA; Stubblefield, SG; Taylor, WM1
Chen, X; He, W; Jiao, Z; Li, Y; Liu, T; Liu, X; Ma, H; Wang, F; Zeng, X; Zhang, J1

Trials

1 trial(s) available for adenine and melphalan

ArticleYear
Safety and efficacy of using a single agent or a phase II agent before instituting standard combination chemotherapy in previously untreated metastatic breast cancer patients: report of a randomized study--Cancer and Leukemia Group B 8642.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1999, Volume: 17, Issue:5

    Topics: Adenine; Adult; Aged; Aminoglycosides; Analysis of Variance; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carboplatin; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Imides; Isoquinolines; Melphalan; Middle Aged; Naphthalimides; Neoplasm Staging; Organophosphonates; Prospective Studies; Survival Analysis; Trimetrexate

1999

Other Studies

10 other study(ies) available for adenine and melphalan

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
[The effect of sarcolysin on nucleic acid synthesis in monolayer cultures of human tumor cells].
    Biulleten' eksperimental'noi biologii i meditsiny, 1970, Volume: 69, Issue:6

    Topics: Adenine; Carbon Isotopes; Culture Techniques; Female; Hemangiosarcoma; Humans; Lysine; Melphalan; Mesenchymoma; Neoplasm Proteins; Ovarian Neoplasms; Pancreatic Neoplasms; RNA, Neoplasm; Stomach Neoplasms; Uridine

1970
Alkylation of DNA by melphalan with special reference to adenine derivatives and adenine-guanine cross-linking.
    Chemico-biological interactions, 1993, Volume: 89, Issue:1

    Topics: Adenine; Adenosine Monophosphate; Alkylation; Animals; Cross-Linking Reagents; Deoxyadenosines; DNA; Guanine; In Vitro Techniques; Magnetic Resonance Spectroscopy; Mass Spectrometry; Melphalan; Salmon

1993
THE CHEMOTHERAPY OF CANCER WITH MASSIVE DOSES UNDER THE PROTECTION OF PERFUSION OF AUTOGENOUS HEMATOPOIETIC TISSUE.
    Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20

    Topics: Adenine; Bone Marrow Transplantation; Breast Neoplasms; DNA; Female; Folic Acid; Humans; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Melphalan; Neoplasms; Ovarian Neoplasms; Perfusion; Sarcoma; Thiotepa; Triethylenemelamine

1964
Adenine-containing DNA-DNA cross-links of antitumor nitrogen mustards.
    Chemical research in toxicology, 2004, Volume: 17, Issue:7

    Topics: Adenine; Animals; Antineoplastic Agents, Alkylating; Cattle; Chromatography, High Pressure Liquid; Cross-Linking Reagents; DNA; DNA Damage; Mechlorethamine; Melphalan; Spectrometry, Mass, Electrospray Ionization

2004
Targeting autophagy augments in vitro and in vivo antimyeloma activity of DNA-damaging chemotherapy.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2011, May-15, Volume: 17, Issue:10

    Topics: Adenine; Animals; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Cell Line, Tumor; DNA Damage; Doxorubicin; Drug Synergism; Humans; Melphalan; Mice; Mice, Inbred C57BL; Mice, SCID; Molecular Targeted Therapy; Multiple Myeloma; Xenograft Model Antitumor Assays

2011
The mechanism of guanine alkylation by nitrogen mustards: a computational study.
    The Journal of organic chemistry, 2012, Jul-20, Volume: 77, Issue:14

    Topics: Adenine; Alkylation; Antineoplastic Agents, Alkylating; Guanine; Kinetics; Mechlorethamine; Melphalan; Molecular Structure; Quantum Theory; Thermodynamics

2012
Protective role of autophagy in matrine‑induced gastric cancer cell death.
    International journal of oncology, 2013, Volume: 42, Issue:4

    Topics: Adenine; Alkaloids; Apoptosis; Autophagy; Cell Line, Tumor; Cell Nucleus; Cell Shape; Cell Survival; Drug Synergism; Humans; Immunoglobulin G; Macrolides; Matrines; Melphalan; Microtubule-Associated Proteins; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Quinolizines; Stomach Neoplasms

2013