adenine has been researched along with mdl-201112 in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (55.56) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Borcherding, DR; Edwards, CK; Linnik, MD; Long, RE; Parmely, MJ; Watts, LM | 1 |
| Borcherding, DR; Edwards, CK; Morrison, DC; Parmely, MJ; Silverstein, R; Zhou, WW | 1 |
| Bluethmann, H; Bonventre, PF; Cullen, CM; Edwards, CK; Heeg, H; Mountz, JD | 1 |
| Borcherding, DR; Bowlin, TL; Edwards, CK; McWhinney, CD | 1 |
| Al-Humidan, A; Al-Sedairy, ST; Al-Sofi, A; Dzimiri, M; Edwards, CK; Khabar, KS | 1 |
| Parmely, MJ; Wang, F; Xia, D | 1 |
| Benda, B; Holstad, M; Korsgren, O; Lycke, N | 1 |
| Holstad, M; Sandler, S | 1 |
| Holstad, M; Sandler, S; Thorvaldson, L | 1 |
9 other study(ies) available for adenine and mdl-201112
| Article | Year |
|---|---|
Effect of the carbocyclic nucleoside analogue MDL 201,112 on inhibition of interferon-gamma-induced priming of Lewis (LEW/N) rat macrophages for enhanced respiratory burst and MHC class II Ia+ antigen expression.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Bordetella pertussis; Brain; Dipyridamole; Down-Regulation; Female; Histocompatibility Antigens Class II; Interferon-gamma; Kinetics; Lipopolysaccharides; Macrophage Activation; Macrophages, Peritoneal; Mycobacterium tuberculosis; Rats; Rats, Inbred Lew; Receptors, Purinergic P1; Receptors, Purinergic P2; Recombinant Proteins; Respiratory Burst; Stimulation, Chemical; Superoxides; Tumor Necrosis Factor-alpha; Zymosan | 1994 |
Adenosine and a related carbocyclic nucleoside analogue selectively inhibit tumor necrosis factor-alpha production and protect mice against endotoxin challenge.
Topics: Adenine; Adenosine; Animals; Cytokines; Endotoxins; Female; Interleukin-1; Macrophage Activation; Macrophages; Mice; Tumor Necrosis Factor-alpha | 1993 |
A fas antigen receptor mutation allows development of toxic shock syndrome toxin-1-induced lethal shock in V beta 8.2 T-cell receptor transgenic mice.
Topics: Adenine; Animals; Bacterial Toxins; Base Sequence; Cells, Cultured; Cyclosporine; Enterotoxins; fas Receptor; Female; Heterozygote; Interleukin-2; Interleukin-6; Isoquinolines; Lipopolysaccharides; Liver; Lymphocyte Activation; Mice; Mice, Transgenic; Molecular Sequence Data; Mutation; Nitrogen Oxides; Receptors, Antigen, T-Cell, alpha-beta; Recombinant Proteins; Shock, Septic; Spleen; Superantigens; Tumor Necrosis Factor-alpha | 1995 |
Adenosine A3 receptor agonists inhibit murine macrophage tumor necrosis factor-alpha production in vitro and in vivo.
Topics: Adenine; Animals; Cell Line; Dose-Response Relationship, Drug; Female; Gene Expression; Genes, Reporter; In Vitro Techniques; Lethal Dose 50; Lipopolysaccharide Receptors; Lipopolysaccharides; Luciferases; Macrophages; Mice; Purinergic P1 Receptor Agonists; Receptors, Purinergic P1; RNA, Messenger; Signal Transduction; Tumor Necrosis Factor-alpha | 1997 |
A carbocyclic nucleoside analogue is a TNF-alpha inhibitor with immunosuppressive action: role of prostaglandin E2 and protein kinase C and comparison with pentoxifylline.
Topics: Adenine; Dinoprostone; Humans; Immunosuppressive Agents; Interleukin-8; Isoantigens; Leukocytes, Mononuclear; Lymphocyte Culture Test, Mixed; Pentoxifylline; Phosphodiesterase Inhibitors; Protein Kinase C; Superantigens; T-Lymphocytes; Tumor Necrosis Factor-alpha | 1998 |
Inhibition of nuclear factor-kappab activation in mouse macrophages and the RAW 264.7 cell line by a synthetic adenyl carbocyclic nucleoside.
Topics: Adenine; Animals; Cell Nucleus; Cells, Cultured; I-kappa B Proteins; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Nucleoproteins; Peptides; Transcriptional Activation; Tumor Necrosis Factor-alpha | 2000 |
Delayed type hypersensitivity-associated cytokines in islet xenotransplantation: limited efficacy of interleukin-2- and tumor necrosis factor-alpha-blockade in interferon-gamma receptor-deficient mice.
Topics: Adenine; Animals; Cyclosporine; Cytokines; Female; Fetal Tissue Transplantation; Graft Rejection; Hypersensitivity, Delayed; Immunosuppressive Agents; Interferon gamma Receptor; Interleukin-2; Islets of Langerhans Transplantation; Lymphocytes; Mice; Mice, Inbred Strains; Mice, Knockout; Receptors, Interferon; Swine; Transplantation, Heterologous; Tumor Necrosis Factor-alpha | 2000 |
A transcriptional inhibitor of TNF-alpha prevents diabetes induced by multiple low-dose streptozotocin injections in mice.
Topics: Adenine; Animals; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Injections; Male; Mice; Mice, Inbred C57BL; RNA, Messenger; Streptozocin; Transcription, Genetic; Tumor Necrosis Factor-alpha | 2001 |
Cytokine release by murine spleen cells following multiple low dose streptozotocin-induced diabetes and treatment with a TNFalpha transcriptional inhibitor.
Topics: Adenine; Animals; Blood Glucose; Carboxymethylcellulose Sodium; Cells, Cultured; Concanavalin A; Cytokines; Diabetes Mellitus, Experimental; Interferon-gamma; Interleukin-10; Male; Mice; Mice, Inbred C57BL; Spleen; Tumor Necrosis Factor-alpha | 2003 |