adenine and mdl-201112

adenine has been researched along with mdl-201112 in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (55.56)18.2507
2000's4 (44.44)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Borcherding, DR; Edwards, CK; Linnik, MD; Long, RE; Parmely, MJ; Watts, LM1
Borcherding, DR; Edwards, CK; Morrison, DC; Parmely, MJ; Silverstein, R; Zhou, WW1
Bluethmann, H; Bonventre, PF; Cullen, CM; Edwards, CK; Heeg, H; Mountz, JD1
Borcherding, DR; Bowlin, TL; Edwards, CK; McWhinney, CD1
Al-Humidan, A; Al-Sedairy, ST; Al-Sofi, A; Dzimiri, M; Edwards, CK; Khabar, KS1
Parmely, MJ; Wang, F; Xia, D1
Benda, B; Holstad, M; Korsgren, O; Lycke, N1
Holstad, M; Sandler, S1
Holstad, M; Sandler, S; Thorvaldson, L1

Other Studies

9 other study(ies) available for adenine and mdl-201112

ArticleYear
Effect of the carbocyclic nucleoside analogue MDL 201,112 on inhibition of interferon-gamma-induced priming of Lewis (LEW/N) rat macrophages for enhanced respiratory burst and MHC class II Ia+ antigen expression.
    Journal of leukocyte biology, 1994, Volume: 56, Issue:2

    Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Bordetella pertussis; Brain; Dipyridamole; Down-Regulation; Female; Histocompatibility Antigens Class II; Interferon-gamma; Kinetics; Lipopolysaccharides; Macrophage Activation; Macrophages, Peritoneal; Mycobacterium tuberculosis; Rats; Rats, Inbred Lew; Receptors, Purinergic P1; Receptors, Purinergic P2; Recombinant Proteins; Respiratory Burst; Stimulation, Chemical; Superoxides; Tumor Necrosis Factor-alpha; Zymosan

1994
Adenosine and a related carbocyclic nucleoside analogue selectively inhibit tumor necrosis factor-alpha production and protect mice against endotoxin challenge.
    Journal of immunology (Baltimore, Md. : 1950), 1993, Jul-01, Volume: 151, Issue:1

    Topics: Adenine; Adenosine; Animals; Cytokines; Endotoxins; Female; Interleukin-1; Macrophage Activation; Macrophages; Mice; Tumor Necrosis Factor-alpha

1993
A fas antigen receptor mutation allows development of toxic shock syndrome toxin-1-induced lethal shock in V beta 8.2 T-cell receptor transgenic mice.
    Pathobiology : journal of immunopathology, molecular and cellular biology, 1995, Volume: 63, Issue:6

    Topics: Adenine; Animals; Bacterial Toxins; Base Sequence; Cells, Cultured; Cyclosporine; Enterotoxins; fas Receptor; Female; Heterozygote; Interleukin-2; Interleukin-6; Isoquinolines; Lipopolysaccharides; Liver; Lymphocyte Activation; Mice; Mice, Transgenic; Molecular Sequence Data; Mutation; Nitrogen Oxides; Receptors, Antigen, T-Cell, alpha-beta; Recombinant Proteins; Shock, Septic; Spleen; Superantigens; Tumor Necrosis Factor-alpha

1995
Adenosine A3 receptor agonists inhibit murine macrophage tumor necrosis factor-alpha production in vitro and in vivo.
    Cellular and molecular biology (Noisy-le-Grand, France), 1997, Volume: 43, Issue:3

    Topics: Adenine; Animals; Cell Line; Dose-Response Relationship, Drug; Female; Gene Expression; Genes, Reporter; In Vitro Techniques; Lethal Dose 50; Lipopolysaccharide Receptors; Lipopolysaccharides; Luciferases; Macrophages; Mice; Purinergic P1 Receptor Agonists; Receptors, Purinergic P1; RNA, Messenger; Signal Transduction; Tumor Necrosis Factor-alpha

1997
A carbocyclic nucleoside analogue is a TNF-alpha inhibitor with immunosuppressive action: role of prostaglandin E2 and protein kinase C and comparison with pentoxifylline.
    Cellular immunology, 1998, Aug-25, Volume: 188, Issue:1

    Topics: Adenine; Dinoprostone; Humans; Immunosuppressive Agents; Interleukin-8; Isoantigens; Leukocytes, Mononuclear; Lymphocyte Culture Test, Mixed; Pentoxifylline; Phosphodiesterase Inhibitors; Protein Kinase C; Superantigens; T-Lymphocytes; Tumor Necrosis Factor-alpha

1998
Inhibition of nuclear factor-kappab activation in mouse macrophages and the RAW 264.7 cell line by a synthetic adenyl carbocyclic nucleoside.
    Biochemical pharmacology, 2000, Sep-01, Volume: 60, Issue:5

    Topics: Adenine; Animals; Cell Nucleus; Cells, Cultured; I-kappa B Proteins; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Nucleoproteins; Peptides; Transcriptional Activation; Tumor Necrosis Factor-alpha

2000
Delayed type hypersensitivity-associated cytokines in islet xenotransplantation: limited efficacy of interleukin-2- and tumor necrosis factor-alpha-blockade in interferon-gamma receptor-deficient mice.
    Xenotransplantation, 2000, Volume: 7, Issue:3

    Topics: Adenine; Animals; Cyclosporine; Cytokines; Female; Fetal Tissue Transplantation; Graft Rejection; Hypersensitivity, Delayed; Immunosuppressive Agents; Interferon gamma Receptor; Interleukin-2; Islets of Langerhans Transplantation; Lymphocytes; Mice; Mice, Inbred Strains; Mice, Knockout; Receptors, Interferon; Swine; Transplantation, Heterologous; Tumor Necrosis Factor-alpha

2000
A transcriptional inhibitor of TNF-alpha prevents diabetes induced by multiple low-dose streptozotocin injections in mice.
    Journal of autoimmunity, 2001, Volume: 16, Issue:4

    Topics: Adenine; Animals; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Injections; Male; Mice; Mice, Inbred C57BL; RNA, Messenger; Streptozocin; Transcription, Genetic; Tumor Necrosis Factor-alpha

2001
Cytokine release by murine spleen cells following multiple low dose streptozotocin-induced diabetes and treatment with a TNFalpha transcriptional inhibitor.
    International immunopharmacology, 2003, Volume: 3, Issue:12

    Topics: Adenine; Animals; Blood Glucose; Carboxymethylcellulose Sodium; Cells, Cultured; Concanavalin A; Cytokines; Diabetes Mellitus, Experimental; Interferon-gamma; Interleukin-10; Male; Mice; Mice, Inbred C57BL; Spleen; Tumor Necrosis Factor-alpha

2003