adenine has been researched along with leupeptins in 38 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (21.05) | 18.7374 |
| 1990's | 3 (7.89) | 18.2507 |
| 2000's | 10 (26.32) | 29.6817 |
| 2010's | 16 (42.11) | 24.3611 |
| 2020's | 1 (2.63) | 2.80 |
| Authors | Studies |
|---|---|
| Heikoop, JC; Just, WW; Meijer, AJ; Strijland, A; Tager, JM; van den Berg, M; Weijers, PJ | 1 |
| Ballard, FJ; Hopgood, MF; Knowles, SE | 1 |
| Hoshi, M; Sawada, H; Sawada, MT; Someno, T | 1 |
| Ballard, FJ; Chandler, CS | 1 |
| Kirwin, P; Mayer, RJ; O'Hare, M; Razooki-Hasan, H; White, DA; Wilde, C | 1 |
| Bernstein, PL; Etlinger, JD; Ludemann, R; Zeman, RJ | 1 |
| Ballard, FJ | 1 |
| Wakeland, JR; Wildenthal, K | 1 |
| Dybedal, MA; Munthe-Kaas, AC; Seglen, PO | 1 |
| Bakke, O; Stang, E | 1 |
| Chiba, K; Hoshi, M; Sato, E | 1 |
| Kovacs, AL; Telbisz, A | 1 |
| Ohshita, T | 1 |
| O'Brien, PJ; Pourahmad, J; Ross, S | 1 |
| Mezey, E; Potter, JJ; Rennie-Tankersley, L | 1 |
| Chau, YP; Chen, JH; Lin, SY; Tai, MH | 1 |
| Brunk, UT; Dalen, H; Stroikin, Y; Terman, A | 1 |
| Brown, NS; Dice, JF; Finn, PF; Franch, HA; Shen, W | 1 |
| Correia, MA; Faouzi, S; Hefner, C; Maher, JJ; Medzihradszky, KF | 1 |
| Cho, CH; Li, ZJ; Sung, JJ; Wu, WK; Wu, YC; Yu, L | 1 |
| Fujiwara, H; Fujiwara, T; Goto, K; Horie, T; Kanamori, H; Maruyama, R; Minatoguchi, S; Miyata, S; Nagao, K; Nagashima, K; Ono, K; Takemura, G; Tsujimoto, A; Ushikoshi, H | 1 |
| Fan, H; Li, B; Wang, G; Wang, H; Wang, X; Ying, Z | 1 |
| Beljanski, V; Knaak, C; Smith, CD | 1 |
| Allamand, V; Carmignac, V; Durbeej, M; Elowsson, L; Gawlik, KI; Körner, Z; Matsumura, C; Svensson, M | 1 |
| Chang, PA; Chen, YY; Long, DX; Mou, XL; Qin, WZ | 1 |
| Ding, ZB; Fan, J; Gu, CY; Hui, B; Liu, WR; Peng, YF; Shi, GM; Shi, YH; Yang, H; Zhou, J | 1 |
| Boncoraglio, A; Carra, S; Crippa, V; Cristofani, R; Giorgetti, E; Poletti, A; Rusmini, P | 1 |
| Angeletti, M; Bonfili, L; Cecarini, V; Cuccioloni, M; Eleuteri, AM; Keller, JN; Mozzicafreddo, M; Rossi, G | 1 |
| Chatterjee, C; Sparks, DL | 1 |
| Lan, D; Wang, W; Zhao, Z; Zhuang, J | 1 |
| Bresgen, N; Eckl, PM; Krenn, MA; Schürz, M; Teufl, B; Uchida, K | 1 |
| Cui, B; Hu, ZW; Hua, F; Huang, B; Jiang, JD; Li, K; Lin, H; Lv, XX; Mu, R; Shang, S; Sun, W; Wang, F; Yan, J; Yu, JJ; Zhang, XW | 1 |
| Chen, G; Fan, W; Lai, Y; Long, Y; Wang, X; Zhu, B | 1 |
| Bao, W; Gu, Y; Ta, L; Wang, K; Xu, Z | 1 |
| Chen, L; Fan, T; Geng, Q; Hu, H; Huang, Z; Mao, Z; Pan, S; Wang, W; Xu, Y; Zhang, B | 1 |
| Bennett, MV; Court-Vazquez, B; Gertner, M; Hwang, JY; Ofengeim, D; Pontarelli, F; Zukin, RS | 1 |
| Kovacevic, Z; Park, KC; Richardson, DR; Sahni, S | 1 |
| Banerjee, A; Bhutda, S; Ghosh, S; Hiray, A; Santra, S; Sinha, AR | 1 |
38 other study(ies) available for adenine and leupeptins
| Article | Year |
|---|---|
Turnover of peroxisomal vesicles by autophagic proteolysis in cultured fibroblasts from Zellweger patients.
Topics: Adenine; Autophagy; Cell Line; Fibroblasts; Fluorescent Antibody Technique; Humans; Hydrolases; Leupeptins; Lysosomes; Membrane Proteins; Microbodies; Zellweger Syndrome | 1992 |
Effects of inhibitors on aldolase breakdown after its microinjection into HeLa cells.
Topics: Adenine; Ammonium Chloride; Ethylmaleimide; Fructose-Bisphosphate Aldolase; HeLa Cells; Humans; Insulin; Leupeptins; Microinjections | 1989 |
Inhibition of starfish oocyte maturation by leupeptin analogs, potent trypsin inhibitors.
Topics: Adenine; Animals; Leupeptins; Oligopeptides; Oocytes; Starfish; Structure-Activity Relationship; Trypsin Inhibitors | 1989 |
Regulation of the breakdown rates of biotin-containing proteins in Swiss 3T3-L1 cells.
Topics: Adenine; Biotin; Cell Line; Electrophoresis, Polyacrylamide Gel; Insulin; Leucine; Leupeptins; Proteins | 1988 |
Secretion-coupled protein degradation: studies on mammary casein.
Topics: Adenine; Amino Acids; Animals; Biological Transport; Caseins; Colchicine; Cytochalasin B; Female; Leupeptins; Mammary Glands, Animal; Organ Culture Techniques; Rabbits; Tunicamycin | 1986 |
Regulation of Ca2+-dependent protein turnover in skeletal muscle by thyroxine.
Topics: Adenine; Animals; Calcium; Dantrolene; Female; Leupeptins; Methylamines; Muscle Proteins; Muscles; Potassium; Rats; Rats, Inbred Strains; Thyroxine | 1986 |
Regulation of protein breakdown by epidermal growth factor in A431 cells.
Topics: Adenine; Ammonium Chloride; Autolysis; Carcinoma, Squamous Cell; Cell Line; Cycloheximide; Epidermal Growth Factor; Fibroblasts; Humans; Hydrogen-Ion Concentration; Insulin; Leupeptins; Lung; Proteins; Time Factors; Vinblastine | 1985 |
The role of lysosomes in the degradation of myofibrillar and non-myofibrillar proteins in heart.
Topics: Adenine; Animals; Chloroquine; Fetus; Insulin; Kinetics; Leupeptins; Lysosomes; Mice; Myocardium; Myofibrils; Proteins | 1985 |
Amino acid control of protein degradation in normal and leukemic human lymphocytes.
Topics: Adenine; Amino Acids; Autophagy; Humans; Leukemia, Lymphoid; Leupeptins; Lymphocytes; Lysosomes; Neoplasm Proteins; Phagocytosis; Propylamines; Proteins | 1984 |
MHC class II-associated invariant chain-induced enlarged endosomal structures: a morphological study.
Topics: Adenine; Antigens, CD; Brefeldin A; Cell Line; Chloroquine; Cyclopentanes; Endocytosis; Endosomes; Fibroblasts; HLA-DR alpha-Chains; HLA-DR Antigens; Humans; Immunohistochemistry; Leupeptins; Lysosomal Membrane Proteins; Lysosomes; Macromolecular Substances; Membrane Glycoproteins; Receptor, IGF Type 2; Recombinant Proteins; Transfection | 1997 |
Detection of in vivo proteasome activity in a starfish oocyte using membrane-impermeant substrate.
Topics: Adenine; Aminopeptidases; Animals; Cell Membrane Permeability; Coumarins; Cyclins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytosol; Fluorescent Dyes; Hydrolysis; Kinetics; Leucine; Leupeptins; Meiosis; Mesylates; Multienzyme Complexes; Oligopeptides; Oocytes; Proteasome Endopeptidase Complex; Spectrometry, Fluorescence; Starfish | 1997 |
Intracellular protein degradation and autophagy in isolated pancreatic acini of the rat.
Topics: Adenine; Amines; Amino Acids; Animals; Autophagy; Cells, Cultured; Enzyme Inhibitors; Kinetics; Leupeptins; Lysosomes; Male; Microscopy, Electron; Pancreas; Protein Biosynthesis; Proteins; Rats; Rats, Long-Evans; Vinblastine | 2000 |
Suppression of autophagy by ethionine administration in male rat liver in vivo.
Topics: Adenine; Adenosine Triphosphate; Animals; Antimetabolites; Centrifugation, Density Gradient; Cysteine Proteinase Inhibitors; Cytosol; Ethionine; L-Lactate Dehydrogenase; Leupeptins; Liver; Lysosomes; Male; Phagosomes; Rats; Rats, Wistar | 2000 |
Lysosomal involvement in hepatocyte cytotoxicity induced by Cu(2+) but not Cd(2+).
Topics: Acridine Orange; Adenine; Animals; Aurothioglucose; Cadmium; Cell Death; Chloroquine; Copper; Endopeptidases; Enzyme Activation; Gentamicins; Leupeptins; Lipid Peroxidation; Liver; Lysosomes; Male; Methylamines; Monensin; Oxidation-Reduction; Pepstatins; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2001 |
Liver alcohol dehydrogenase is degraded by the ubiquitin-proteasome pathway.
Topics: Acetylcysteine; Adenine; Alcohol Dehydrogenase; Animals; Calpain; Cells, Cultured; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dihydrotestosterone; Electrophoresis, Polyacrylamide Gel; Hepatocytes; Leupeptins; Liver; Lysosomes; Male; Multienzyme Complexes; Precipitin Tests; Proteasome Endopeptidase Complex; Rats; Rats, Sprague-Dawley; Ubiquitins | 2001 |
Endostatin induces autophagic cell death in EAhy926 human endothelial cells.
Topics: Acridine Orange; Adenine; Animals; Antineoplastic Agents; Apoptosis; Aprotinin; Blotting, Western; Caspases; Cell Death; Cells, Cultured; CHO Cells; Cloning, Molecular; Cricetinae; Cysteine; Cysteine Endopeptidases; Dose-Response Relationship, Drug; Endostatins; Endothelial Cells; Endothelium, Vascular; Enzyme Activation; Flow Cytometry; Glutathione Transferase; Humans; Immunohistochemistry; Leupeptins; Lysosomes; Microscopy, Electron; Microscopy, Phase-Contrast; Oxidative Stress; Reactive Oxygen Species; Recombinant Proteins; Serine; Time Factors | 2003 |
Testing the "garbage" accumulation theory of ageing: mitotic activity protects cells from death induced by inhibition of autophagy.
Topics: Adenine; Aging; Astrocytes; Autophagy; Cell Line; Cell Survival; Cellular Senescence; Cysteine Proteinase Inhibitors; Fibroblasts; Humans; Leupeptins; Mitosis; Phosphoinositide-3 Kinase Inhibitors | 2005 |
Akt and Mammalian target of rapamycin regulate separate systems of proteolysis in renal tubular cells.
Topics: Acetylcysteine; Adenine; Animals; Autophagy; Cell Line; Chromones; Epidermal Growth Factor; Glyceraldehyde-3-Phosphate Dehydrogenases; Kidney Tubules; Leupeptins; Lysosomes; Methylamines; Morpholines; PAX2 Transcription Factor; Peptide Hydrolases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proteasome Endopeptidase Complex; Protein Kinases; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases | 2006 |
Characterization of the physiological turnover of native and inactivated cytochromes P450 3A in cultured rat hepatocytes: a role for the cytosolic AAA ATPase p97?
Topics: Adenine; Adenosine Triphosphatases; Ammonium Chloride; Animals; Autophagy; Boronic Acids; Cell Cycle Proteins; Cross-Linking Reagents; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dexamethasone; Dicarbethoxydihydrocollidine; Formaldehyde; Hepatocytes; Leupeptins; Lysosomes; Male; Nuclear Proteins; Polymers; Proteasome Endopeptidase Complex; Rats; Rats, Sprague-Dawley; Saccharomyces cerevisiae Proteins; Troleandomycin; Ubiquitin; Valosin Containing Protein | 2007 |
Induction of autophagy by proteasome inhibitor is associated with proliferative arrest in colon cancer cells.
Topics: Adenine; Autophagy; Cell Division; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Cysteine Proteinase Inhibitors; Cytoplasmic Vesicles; G2 Phase; Humans; Leupeptins; Microtubule-Associated Proteins; Proteasome Inhibitors; Vacuoles | 2008 |
Morphological and biochemical characterization of basal and starvation-induced autophagy in isolated adult rat cardiomyocytes.
Topics: Adenine; Adenosine Triphosphate; Animals; Autophagy; Cell Shape; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Glucose; Leupeptins; Male; Microtubule-Associated Proteins; Myocytes, Cardiac; Necrosis; Rats; Rats, Sprague-Dawley; RNA Interference; RNA, Small Interfering; Sirolimus; Time Factors; Vacuoles | 2008 |
Degradation of TDP-43 and its pathogenic form by autophagy and the ubiquitin-proteasome system.
Topics: Adenine; Autophagy; Cell Line; DNA-Binding Proteins; Humans; Leupeptins; Pepstatins; Peptide Fragments; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Trehalose; Ubiquitin | 2010 |
A novel sphingosine kinase inhibitor induces autophagy in tumor cells.
Topics: Adamantane; Adenine; Animals; Apoptosis; Autophagy; Blotting, Western; Cell Cycle; Electrophoresis, Polyacrylamide Gel; Humans; Leupeptins; Mice; Mice, SCID; Microscopy, Confocal; Microtubule-Associated Proteins; Mitochondrial Membranes; Neoplasm Transplantation; Neoplasms, Experimental; Phosphotransferases (Alcohol Group Acceptor); Polymerase Chain Reaction; Pyridines; RNA, Small Interfering; Tumor Cells, Cultured; Unfolded Protein Response | 2010 |
Autophagy is increased in laminin α2 chain-deficient muscle and its inhibition improves muscle morphology in a mouse model of MDC1A.
Topics: Adenine; Animals; Apoptosis; Autophagy; Behavior, Animal; Disease Models, Animal; Drug Therapy, Combination; Fibrosis; Gene Expression Regulation; Injections; Laminin; Leupeptins; Mice; Motor Activity; Muscles; Muscular Atrophy; Muscular Dystrophies; Peripheral Nervous System Diseases; Phenotype; Phosphorylation; Proto-Oncogene Proteins c-akt; Regeneration; Survival Analysis | 2011 |
Degradation of mouse NTE-related esterase by macroautophagy and the proteasome.
Topics: Adenine; Animals; Autophagy; Carboxylic Ester Hydrolases; Cycloheximide; Green Fluorescent Proteins; HEK293 Cells; Humans; Leupeptins; Mice; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Biosynthesis; Protein Structure, Tertiary; Proteolysis; Recombinant Fusion Proteins | 2012 |
Proteasome inhibitor interacts synergistically with autophagy inhibitor to suppress proliferation and induce apoptosis in hepatocellular carcinoma.
Topics: Adenine; Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Boronic Acids; Bortezomib; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Chloroquine; Cysteine Proteinase Inhibitors; Humans; Leupeptins; Membrane Proteins; Microtubule-Associated Proteins; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines | 2012 |
Clearance of the mutant androgen receptor in motoneuronal models of spinal and bulbar muscular atrophy.
Topics: Adaptor Proteins, Signal Transducing; Adenine; Animals; Autophagy; Cell Line, Transformed; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Gene Expression Regulation; Green Fluorescent Proteins; Heat-Shock Proteins; HSP20 Heat-Shock Proteins; Humans; Leupeptins; Mice; Molecular Chaperones; Motor Neurons; Muscle Proteins; Mutation; Receptors, Androgen; RNA, Small Interfering; Sequestosome-1 Protein; Signal Transduction; Testosterone; Trehalose | 2013 |
Wild type and mutant amyloid precursor proteins influence downstream effects of proteasome and autophagy inhibition.
Topics: Adenine; Amino Acid Substitution; Amyloid beta-Protein Precursor; Autophagy; Blotting, Western; Cathepsin B; Cell Line, Tumor; Cell Survival; Cysteine Proteinase Inhibitors; Humans; Immunohistochemistry; Leupeptins; Mutant Proteins; Mutation; Proteasome Endopeptidase Complex; Proteolysis | 2014 |
Hepatic lipase release is inhibited by a purinergic induction of autophagy.
Topics: Adenine; Adenosine Diphosphate; Autophagy; Endocytosis; Hep G2 Cells; Hepatocytes; Humans; Leupeptins; Lipase; Microtubule-Associated Proteins; Protein Isoforms; Receptors, Purinergic P2; RNA Interference; RNA, Small Interfering; Time Factors | 2014 |
Proteasome inhibitor-induced autophagy in PC12 cells overexpressing A53T mutant α-synuclein.
Topics: Adenine; alpha-Synuclein; Animals; Autophagy; Cell Death; Gene Expression; Leupeptins; Mutation; PC12 Cells; Proteasome Inhibitors; Rats; TOR Serine-Threonine Kinases | 2015 |
Ferritin-stimulated lipid peroxidation, lysosomal leak, and macroautophagy promote lysosomal "metastability" in primary hepatocytes determining in vitro cell survival.
Topics: Adenine; Aldehydes; Animals; Apoptosis; Autophagy; Culture Media, Conditioned; Endocytosis; Epidermal Growth Factor; Female; Ferritins; Glutathione; Glutathione Disulfide; Hepatocytes; Intracellular Membranes; Iron Chelating Agents; Leupeptins; Liver; Lysosomes; Molecular Imaging; Permeability; Primary Cell Culture; Protease Inhibitors; Protein Aggregates; Rats; Rats, Inbred F344 | 2015 |
TRB3 links insulin/IGF to tumour promotion by interacting with p62 and impeding autophagic/proteasomal degradations.
Topics: Adaptor Proteins, Signal Transducing; Adenine; Animals; Autophagy; Cell Cycle Proteins; Cell Movement; Gene Expression Regulation, Neoplastic; Humans; Insulin; Insulin Receptor Substrate Proteins; Insulin-Like Growth Factor I; Leupeptins; Male; Mice; Mice, Inbred C57BL; Mice, Nude; Neoplasm Metastasis; Neoplasms, Experimental; Proteasome Endopeptidase Complex; Protein Serine-Threonine Kinases; Repressor Proteins; Sequestosome-1 Protein; Tissue Array Analysis; Ubiquitin | 2015 |
NPAS4 Facilitates the Autophagic Clearance of Endogenous Tau in Rat Cortical Neurons.
Topics: Adenine; Animals; Autophagy; Basic Helix-Loop-Helix Transcription Factors; Cells, Cultured; Cerebral Cortex; Chloroquine; Cyclin-Dependent Kinase 5; Glycogen Synthase Kinase 3; Leupeptins; Neurons; Proteolysis; Rats; Rats, Sprague-Dawley; tau Proteins | 2016 |
Induction of autophagy by the MG‑132 proteasome inhibitor is associated with endoplasmic reticulum stress in MCF‑7 cells.
Topics: Adenine; Apoptosis; Autophagy; Cinnamates; Drug Synergism; Endoplasmic Reticulum Stress; Humans; Leupeptins; MCF-7 Cells; Proteasome Inhibitors; Thiourea | 2016 |
Associations between autophagy, the ubiquitin-proteasome system and endoplasmic reticulum stress in hypoxia-deoxygenation or ischemia-reperfusion.
Topics: Adenine; Animals; Apoptosis; Autophagy; Cell Hypoxia; Cell Line; Cell Survival; Doxorubicin; Endoplasmic Reticulum Stress; Histone Deacetylase 6; Histone Deacetylases; Leupeptins; Lung; Male; NF-kappa B; Oxygen; Proteasome Endopeptidase Complex; Rats; Reperfusion Injury; Sirolimus; Ubiquitin | 2016 |
Global ischemia induces lysosomal-mediated degradation of mTOR and activation of autophagy in hippocampal neurons destined to die.
Topics: Acetylcysteine; Adenine; AMP-Activated Protein Kinases; Animals; Autophagy; Autophagy-Related Protein-1 Homolog; Beclin-1; Cells, Cultured; Hippocampus; Ischemia; Leupeptins; Lysosomes; Male; Microtubule-Associated Proteins; Neurons; Phosphorylation; Rats; RNA Interference; Sirolimus; TOR Serine-Threonine Kinases | 2017 |
Two mechanisms involving the autophagic and proteasomal pathways process the metastasis suppressor protein, N-myc downstream regulated gene 1.
Topics: Adenine; Antineoplastic Agents; Autophagy; Benzoates; Bridged Bicyclo Compounds, Heterocyclic; Cell Cycle Proteins; Cell Line, Tumor; Cell Movement; Epithelial Cells; Gene Expression Regulation, Neoplastic; Glycogen Synthase Kinase 3 beta; Humans; Immediate-Early Proteins; Intracellular Signaling Peptides and Proteins; Iron Chelating Agents; Leupeptins; Macrolides; Microtubule-Associated Proteins; Pancreatic Ducts; Phosphorylation; Proteasome Endopeptidase Complex; Protein Isoforms; Protein Serine-Threonine Kinases; Proteolysis; Signal Transduction; Thiosemicarbazones | 2019 |
Differential Ubiquitination as an Effective Strategy Employed by the Blood-Brain Barrier for Prevention of Bacterial Transcytosis.
Topics: Adenine; Anti-Bacterial Agents; Autophagy; Biomarkers; Blood-Brain Barrier; Cell Line; Cell Survival; Endothelial Cells; Gene Expression Regulation, Bacterial; Gentamicins; Humans; Leupeptins; Optical Imaging; Penicillins; Proteasome Endopeptidase Complex; Streptococcus pneumoniae; Ubiquitination; Ubiquitins | 2022 |