Compounds > adenine

adenine and indazoles

adenine has been researched along with indazoles in 14 studies

Research

Studies (14)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (7.14)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (14.29)	29.6817
2010's	9 (64.29)	24.3611
2020's	2 (14.29)	2.80

Authors

Authors	Studies
Bamborough, P; Brown, MJ; Christopher, JA; Chung, CW; Mellor, GW	1
de Serres, FJ; Ong, T	1
Bookman, RJ; Frei, CW; Frohock, JI; Lieb, T; Salathe, M	1
Almeida, S; Gil, J; Oliveira, CR; Rego, AC	1
Borda, E; Busch, L; Miozza, V; S-Borda, L	1
Chen, Z; Lin, H; Liu, H; Sun, Q; Yuan, G; Zhang, L; Zhou, Q	1
Chrysikos, D; Dimopoulos, MA; Papadimitriou, CA; Psaltopoulou, T; Sergentanis, TN; Zagouri, F	1
Bruserud, Ø; Hatfield, KJ; Nepstad, I; Reikvam, H	1
Dixon, SJ; Jirik, FR; Kashishian, A; Lannutti, BJ; Pereverzev, A; Puri, KD; Shugg, RP; Sims, SM; Steiner, BH; Tanabe, N; Thomson, A	1
Cao, B; Hou, T; Li, D; Li, Y; Mao, X; Pan, P; Wang, M; Zhu, J	1
Akare, UR; Bandaru, S; Dunna, NR; Gutlapalli, VR; Nayarisseri, A; Rajadhyax, S; Yadav, M	1
Akritidou, MA; Anagnostopoulos, A; Belloni, D; Chartomatsidou, E; Ferrero, E; Ghia, P; Kotta, K; Ntoufa, S; Papakonstantinou, N; Rosenquist, R; Rovida, A; Stamatopoulos, K; Stavroyianni, N; Trangas, T	1
Cho, YK; Choi, MG; Huh, JH; Ihm, SH; Kang, JG; Kim, SH; Lee, SJ	1
Alinari, L; Baiocchi, RA; Byrd, JC; Chen, TL; Harrington, B; Hertlein, E; Lehman, AM; Orlemans, E; Prouty, A; Sampath, D; Sloan, S; Truxall, J; Wasmuth, R; Woyach, JA	1

Reviews

1 review(s) available for adenine and indazoles

Article	Year
Hsp90 inhibitors in breast cancer: a systematic review. Breast (Edinburgh, Scotland), 2013, Volume: 22, Issue:5 Topics: Adenine; Antineoplastic Agents; Benzamides; Benzoquinones; Biomarkers, Tumor; Female; Glycine; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; Indazoles; Isoxazoles; Lactams, Macrocyclic; Pyridines; Resorcinols; Triazoles; Triple Negative Breast Neoplasms	2013

Other Studies

13 other study(ies) available for adenine and indazoles

Article	Year
Selectivity of kinase inhibitor fragments. Journal of medicinal chemistry, 2011, Jul-28, Volume: 54, Issue:14 Topics: Adenine; Adenosine Triphosphate; Aniline Compounds; Binding Sites; Enzyme Inhibitors; High-Throughput Screening Assays; Indazoles; Indoles; Isoenzymes; Models, Molecular; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphotransferases; Protein Binding; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-pim-1; Pyridines; Pyrimidines; Quantitative Structure-Activity Relationship; Small Molecule Libraries	2011
Genetic analysis of adenine-3 mutants induced by hycanthone, lucanthone and their indazole analogs in Neurospora crassa. Journal of environmental pathology and toxicology, 1980, Volume: 4, Issue:5-6 Topics: Adenine; Chromosomes; Genetic Complementation Test; Hycanthone; Indazoles; Lucanthone; Mutagens; Neurospora crassa; Pyrazoles; Thioxanthenes	1980
Prolonged increase in ciliary beat frequency after short-term purinergic stimulation in human airway epithelial cells. The Journal of physiology, 2002, Jan-15, Volume: 538, Issue:Pt 2 Topics: Adenine; Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Animals; Calcium; Cells, Cultured; Cilia; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Epithelial Cells; Extracellular Space; Humans; Indazoles; Intracellular Membranes; Nitric Oxide Synthase; Osmolar Concentration; Purines; Sheep; Time Factors; Trachea	2002
Cytosolic and mitochondrial ROS in staurosporine-induced retinal cell apoptosis. Free radical biology & medicine, 2003, Dec-01, Volume: 35, Issue:11 Topics: Adenine; Allopurinol; Animals; Antioxidants; Apoptosis; Arachidonic Acids; Benzoquinones; Blotting, Western; Calcium; Carbon; Caspase 3; Caspases; Cell Death; Cell Survival; Chick Embryo; Chromans; Coloring Agents; Cytosol; DNA Fragmentation; Enzyme Inhibitors; Glutathione; In Situ Nick-End Labeling; Indazoles; Metalloporphyrins; Mitochondria; Neurons; Nitric Oxide Synthase; Oligomycins; Protein Isoforms; Reactive Oxygen Species; Retina; Rotenone; Staurosporine; Tetrazolium Salts; Thiazoles; Time Factors; Ubiquinone; Uncoupling Agents; Xanthine Oxidase	2003
Increase nitric oxide synthase activity in parotid glands from rats with experimental periodontitis. Oral diseases, 2010, Volume: 16, Issue:8 Topics: Adenine; Amylases; Animals; Calcium; Cyclic AMP-Dependent Protein Kinase Catalytic Subunits; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Egtazic Acid; Enzyme Inhibitors; Guanidines; Indazoles; Indomethacin; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Organ Size; Ornithine; Parotid Gland; Periodontitis; Piperazines; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Salivary Proteins and Peptides; Thiazoles	2010
Adenosine monophosphate-activated protein kinase/mammalian target of rapamycin-dependent autophagy protects human dental pulp cells against hypoxia. Journal of endodontics, 2013, Volume: 39, Issue:6 Topics: Adenine; AMP-Activated Protein Kinases; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Autophagy-Related Protein 12; Autophagy-Related Protein 5; Beclin-1; Cell Culture Techniques; Cell Hypoxia; Cell Survival; Cells, Cultured; Dental Pulp; Genetic Vectors; Guanylate Cyclase; Humans; Hypoxia-Inducible Factor 1; Indazoles; Membrane Proteins; Microtubule-Associated Proteins; Plasmids; Proto-Oncogene Proteins; Small Ubiquitin-Related Modifier Proteins; TOR Serine-Threonine Kinases; Tumor Suppressor Proteins	2013
Pharmacological targeting of the PI3K/mTOR pathway alters the release of angioregulatory mediators both from primary human acute myeloid leukemia cells and their neighboring stromal cells. Oncotarget, 2013, Volume: 4, Issue:6 Topics: Adenine; Adult; Aged; Aged, 80 and over; Bone Marrow Cells; Cytogenetics; Cytokines; Female; Humans; Indazoles; Leukemia, Myeloid, Acute; Male; Middle Aged; Molecular Targeted Therapy; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; RNA, Messenger; Signal Transduction; Sirolimus; Stromal Cells; Sulfonamides; TOR Serine-Threonine Kinases; Young Adult	2013
Effects of isoform-selective phosphatidylinositol 3-kinase inhibitors on osteoclasts: actions on cytoskeletal organization, survival, and resorption. The Journal of biological chemistry, 2013, Dec-06, Volume: 288, Issue:49 Topics: Adenine; Androstadienes; Animals; Bone Resorption; Cell Survival; Chromones; Cytoskeleton; Indazoles; Isoenzymes; Morpholines; Osteoclasts; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Quinazolines; Rabbits; RANK Ligand; Rats; Sulfonamides; Wortmannin	2013
Theoretical studies on beta and delta isoform-specific binding mechanisms of phosphoinositide 3-kinase inhibitors. Molecular bioSystems, 2014, Mar-04, Volume: 10, Issue:3 Topics: Adenine; Binding Sites; Enzyme Inhibitors; Hydrogen Bonding; Indazoles; Models, Molecular; Molecular Conformation; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Binding; Protein Conformation; Protein Isoforms; Quinazolines; Sulfonamides	2014
Multiclass comparative virtual screening to identify novel Hsp90 inhibitors: a therapeutic breast cancer drug target. Current topics in medicinal chemistry, 2015, Volume: 15, Issue:1 Topics: Adenine; Anisoles; Antineoplastic Agents; Benzamides; Binding Sites; Breast Neoplasms; Catechin; Databases, Chemical; Drug Discovery; Female; Gene Expression; Glycine; Heterocyclic Compounds, 2-Ring; High-Throughput Screening Assays; HSP90 Heat-Shock Proteins; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Indazoles; Ligands; Molecular Docking Simulation; Protein Binding; Pyrazoles; Pyridines; Static Electricity; Structure-Activity Relationship; User-Computer Interface	2015
Inhibition of EZH2 and immune signaling exerts synergistic antitumor effects in chronic lymphocytic leukemia. Blood advances, 2019, 06-25, Volume: 3, Issue:12 Topics: Adenine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; B-Lymphocytes; Bridged Bicyclo Compounds, Heterocyclic; Down-Regulation; Drug Synergism; Enhancer of Zeste Homolog 2 Protein; Enzyme Inhibitors; Histones; Humans; Indazoles; Indoles; Leukemia, Lymphocytic, Chronic, B-Cell; Piperidines; Purines; Pyrazoles; Pyridones; Pyrimidines; Quinazolinones; Signal Transduction; Sulfonamides; Tumor Microenvironment	2019
Heat Shock Protein 90 Inhibitors AUY922, BIIB021 and SNX5422 Induce Bim-mediated Death of Thyroid Carcinoma Cells. Anticancer research, 2020, Volume: 40, Issue:11 Topics: Adenine; Apoptosis; Bcl-2-Like Protein 11; Benzamides; Cell Line, Tumor; Cell Survival; Extracellular Signal-Regulated MAP Kinases; Glycine; HSP90 Heat-Shock Proteins; Humans; Indazoles; Isoxazoles; Proto-Oncogene Proteins c-akt; Pyridines; Resorcinols; Signal Transduction; Thyroid Neoplasms	2020
Preclinical evaluation of the Hsp90 inhibitor SNX-5422 in ibrutinib resistant CLL. Journal of hematology & oncology, 2021, 02-24, Volume: 14, Issue:1 Topics: Adenine; Animals; Antineoplastic Agents; Benzamides; Cell Line, Tumor; Drug Resistance, Neoplasm; Glycine; HSP90 Heat-Shock Proteins; Humans; Indazoles; Leukemia, Lymphocytic, Chronic, B-Cell; Mice; Piperidines; Protein Kinase Inhibitors	2021