adenine has been researched along with hypoxanthine in 237 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 86 (36.29) | 18.7374 |
| 1990's | 65 (27.43) | 18.2507 |
| 2000's | 52 (21.94) | 29.6817 |
| 2010's | 28 (11.81) | 24.3611 |
| 2020's | 6 (2.53) | 2.80 |
| Authors | Studies |
|---|---|
| Carlson, EE; Goswami, M; Wilke, KE | 1 |
| Balaska, S; Diallinas, G; Dimitrakis, S; Gavriil, ES; Lambrinidis, G; Lougiakis, N; Marakos, P; Mikros, E; Papadaki, G; Pouli, N | 1 |
| Ko, RC; Wong, PC | 1 |
| Chilson, OP | 1 |
| Brèthes, D; Chevallier, J; Napias, C; Torchut, E | 1 |
| Alamillo, JM; Cárdenas, J; Pérez-Vicente, R; Pineda, M | 1 |
| Brulé, D; Sarwar, G; Savoie, L | 1 |
| Ishii, T; Karasawa, Y; Kubota, T | 1 |
| Bianchi, V; Pontis, E; Reichard, P | 1 |
| Camiña, F; Castro-Gago, M; Lojo, S; Rodríguez-Núñez, A; Rodríguez-Segade, S | 1 |
| Baghestanian, M; Chiba, P; Kommer, W; Kraupp, M; Marz, R; Prager, G; Razavi, M | 1 |
| Marlewski, M; Rutkowski, B; Smolenski, RT; Swierczynski, J; Zydowo, MM | 1 |
| Berman, PA; Human, L | 1 |
| Conroy, MC; Dong, MK; Gilbertsen, RB; Kossarek, LM; Kostlan, CR; Sircar, JC | 1 |
| Cheung, KS; Hedstrom, L; Wang, CC | 1 |
| Gross, CJ; Savaiano, DA | 1 |
| Marlewski, M; Smoleński, RT | 1 |
| Mori, K; Noguchi, M; Ozawa, K; Wada, Y; Zaima, M | 1 |
| de Jong, JW; Den Boer, PJ; Grootegoed, JA; Mackenbach, P | 1 |
| Behrman, HR; Lavy, G; Polan, ML | 1 |
| Aalto, TK; Raivio, KO | 1 |
| Akiyama, Y; Hashimoto, H; Kitoh, T; Kubota, M; Mikawa, H; Shimizu, T; Takimoto, T | 1 |
| Brandová, J; Novák, L; Stípek, S; Trojan, S | 1 |
| Glässer, D; Iwig, M | 1 |
| Bowditch, J; Brown, AK; Dow, JW; Raeside, DL | 1 |
| Barankiewicz, J; Cohen, A | 3 |
| Fairbanks, LD; Simmonds, HA; Webster, DR | 1 |
| Cabrera, EJ; Sergio, SL | 1 |
| Hüttermann, J; Sieber, K | 1 |
| Beck, J; Ullman, B | 1 |
| Crifò, C; Gerber, G; Giacomello, A; Salerno, C; Siems, W; Werner, A | 1 |
| Hanson, S; Ullman, B | 1 |
| Khramtsova, SN; Pimenov, AM; Potapova, GI; Shapot, VS; Tikhonov, IuV; Toguzov, RT | 1 |
| Brajter-Toth, A; Volk, KJ; Yost, RA | 1 |
| Jira, TB; Michaelis, D; Rjasanowski, IM; Schäfer, JH | 1 |
| Holmes, EW; Manfredi, JP | 1 |
| Brennan, CA; Gumport, RI; Van Cleve, MD | 1 |
| Capuozzo, E; Crifò, C; Gigante, MC; Salerno, C | 1 |
| Beck, JT; Ullman, B | 1 |
| Plagemann, PG; Woffendin, C; Wohlhueter, RM | 1 |
| Duran, M; Rijkers, GT; Scharenberg, JG; Spaapen, LJ; Staal, GE; Zegers, BJ | 1 |
| Laten, HM; Valentine, PJ; van Kast, CA | 1 |
| Andersen, PT; Bacher, T; Stentoft, J | 1 |
| Daly, JW; Eger, K; Padgett, WL | 1 |
| Abd-Elfattah, AS; Brunsting, LA; Doherty, NE; Jessen, ME; Lekven, J; Wechsler, AS | 1 |
| Vettenranta, K | 1 |
| Allan, PW; Bennett, LL; Brockman, RW; Rose, LM; Shaddix, SC | 1 |
| Domin, BA; Mahony, WB; Zimmerman, TP | 2 |
| Domin, BA; Mahony, WB; McConnell, RT; Zimmerman, TP | 1 |
| Gross, CJ; Savaiano, DA; Stiles, JE | 1 |
| Yoshino, M | 1 |
| Aronow, B; Ullman, B | 1 |
| Bontemps, F; Hers, HG; Van den Berghe, G | 1 |
| Aronow, B; Hollingsworth, P; McCartan, K; Patrick, J; Toll, D; Ullman, B | 1 |
| Murray, V | 1 |
| McCartan, K; Patrick, J; Ullman, B | 1 |
| Di Stefano, A; Marinello, E; Pizzichini, M | 1 |
| Spector, R | 1 |
| Kamatani, N; Kitamura, M; Kojima, T; Nishina, T; Nishioka, K | 1 |
| Franzus, MJ; Malcolm, GB; Pine, L | 1 |
| Arnold, ST; Cysyk, RL | 1 |
| Fischer, AG; Post, GR | 1 |
| Barankiewicz, J; Cohen, A; Kaplinsky, C; Yeger, H | 1 |
| Müller, MM; Rumpold, H; Schopf, G | 1 |
| Klem, J; Kopff, M; Zachara, B; Zakrzewska, I | 1 |
| Ehinger, BE; Fredholm, BB; Lindström, K; Perez, MT | 1 |
| Abidi, TF; Plagemann, PG; Stollar, V; Woffendin, C | 1 |
| Fox, IH; Jiménez, ML; Mateos, FA; Puig, JG | 1 |
| Betz, AL | 1 |
| Plagemann, PG; Wohlhueter, RM | 1 |
| Flodgaard, H; Klenow, H | 1 |
| Farley, BA; Ohlsson-Wilhelm, BM; Rowley, PT; Rudolph, NS | 1 |
| Lewis, S; Yudkoff, M | 1 |
| Griffin, K; Sutherland, JC | 1 |
| Adamson, DJ; Bennett, LL; Brockman, RW; Rose, LM; Smithers, D | 1 |
| Cybulski, RL; Fry, DW; Goldman, ID | 1 |
| Honeysett, JM; Howell, SB; King, ME | 1 |
| Canellakis, ES; Vitkauskas, G | 1 |
| Al-Safi, SA; Maddocks, JL | 1 |
| Kessler-Icekson, G; Sperling, O; Wasserman, L; Zoref-Shani, E | 1 |
| Boliska, SA; Bols, NC; Mosser, DD; Snyder, FF | 1 |
| Beaman, TC; Endo, T; Freese, E; Hitchins, AD; Ochi, K; Vasantha, N | 1 |
| Sheehan, TG; Tully, ER | 1 |
| Fox, IH; Puig, JG | 1 |
| Disteche, CM; Horn, PL; Martin, GM; Ogburn, CE; Turker, MS | 1 |
| Holliss, DG; Humphrey, SM; Seelye, RN | 1 |
| Holland, MJ; Murphy, E; Schein, R | 1 |
| Gross, CJ; Henderson, LM; Salati, LM; Savaiano, DA | 1 |
| Gröbner, W; Löffler, W; Reiter, S; Zöllner, N | 1 |
| Murphy, JM; Tully, ER | 1 |
| Shainberg, A; Sperling, O; Zoref-Shani, E | 1 |
| Hansen, BD; Hendricks, LD; Pappas, MG; Webster, HK | 1 |
| Engström, W; Zetterberg, A | 1 |
| Fredholm, BB; Lerner, U | 1 |
| Clifford, AJ; Savaiano, DA | 1 |
| Aruoma, OI; Chimel, K; Cross, CE; Halliwell, B; Jenner, A; Spencer, JP; Wu, R | 1 |
| Abbondandolo, A; Aprile, A; Arena, G; Bonatti, S; Cavalieri, Z; Pellerano, P; Rocco, M; Sailer, K; Viaggi, S | 1 |
| Eklof, B; Jabs, CM; Neglen, P | 1 |
| Hayek, G; Jacomelli, G; Micheli, V; Pescaglini, M; Pompucci, G; Rocchigiani, M; Sestini, S | 1 |
| de Miguel, E; Gil, A; Mateos, FA; Miranda, ME; Pérez de Ayala, C; Puig, JG; Torres, RJ | 1 |
| Baumgarten, I; Harley, EH | 1 |
| Ceballos, G; Rubio, R | 1 |
| Fujino, Y; Hiraoka, K; Ku, Y; Kuroda, Y; Matsumoto, S; Morita, A; Saitoh, Y; Tanioka, Y | 1 |
| Bianchi, V; Bonvini, P; Borella, S; Ferraro, P; Reichard, P | 1 |
| Bromberg, Y; Brosh, S; Sidi, Y; Sperling, O; Zoref-Shani, E | 1 |
| Liras, A; Llorente, P; Rotllan, P | 1 |
| Sciotti, VM; Van Wylen, DG | 1 |
| Meno, JR; Ngai, AC; Winn, HR | 1 |
| Christensen, U; Dissing, J; Rangaard, B | 1 |
| Melton, DW; Wu, CL | 1 |
| Grauel, EL; Grune, T; Schmidt, H; Siems, WG | 1 |
| Melton, DW; Redhead, NJ; Selfridge, J; Wu, CL | 1 |
| Krasuski, A; Marlewski, M; Smoleński, RT | 1 |
| Brèthes, D; Chevallier, J; Ferreira, T; Napias, C | 3 |
| Barankiewicz, J; Mitchell, BS; Spychala, J | 1 |
| Acevedo, CG; Bravo, I; Ramírez, M; Rojas, S | 1 |
| Dubois, S; Eritja, R; Guschlbauer, W; Thielking, V | 1 |
| Cascante, M; Curto, R; Sorribas, A; Voit, EO | 1 |
| Grune, T; Holzhütter, HG; Schwendel, A; Siems, WG | 1 |
| Oliveira, CR; Rego, AC; Santos, MS | 1 |
| Elder, RH; Hang, B; Margison, GP; Singer, B | 1 |
| Hazell, SL; Mendz, GL; Shepley, AJ; Smith, MA | 1 |
| Arvidson, DN; Brennan, RG; Haldimann, A; Lu, F; Schumacher, MA; Wanner, BL; Zalkin, H | 1 |
| Kobayashi, T; Okada, Y; Yamada, T | 1 |
| Manthei, SA; Reiling, CM; Van Wylen, DG | 1 |
| Griesmacher, A; Müller, MM; Weigel, G | 1 |
| Doyle, PS; Kanaani, J; Wang, CC | 1 |
| Halliwell, B; Ince, PG; Jenner, A; Jenner, P; Lyras, L; Perry, EK; Perry, RH | 1 |
| Chow, M; Koo, J; Ng, P; Rubin, H | 1 |
| Jovin, TM; Klement, R; Liquier, J; Mohammadi, S; Shchyolkina, AK; Taillandier, E | 1 |
| Richardt, G; Schreieck, J | 1 |
| Brèthes, D; Chevallier, J; Ferreira, T; Napias, C; Paumard, P | 1 |
| Levy, M; Miller, SL | 1 |
| Dogliotti, E; Fortini, P; Laval, J; Parlanti, E; Sidorkina, OM | 1 |
| Bromberg, Y; Feinstein, S; Frishberg, Y; Sperling, O; Zoref-Shani, E | 1 |
| Asaeda, A; Asagoshi, K; Ide, H; Kubo, K; Matsuyama, S; Murakami, A; Takamori, Y; Tano, K | 1 |
| Samson, LD; Wyatt, MD | 1 |
| Eng, KH; Min, HW; Moochhala, S | 1 |
| Bain, D; Castro, MG; Fairbanks, LD; Larregina, AT; Löwenstein, PR; Morelli, AE; Simmonds, HA; Southgate, TD | 1 |
| Bohr, VA; Ganunis, R; Machwe, A; Orren, DK | 1 |
| Aden, U; Berman, RF; Fredholm, BB; O'Connor, WT | 1 |
| Camp, DM; Harel, E; Juneau, PL; LeWitt, PA; Loeffler, DA | 1 |
| Baldwin, SA; Cass, CE; LaRivière, CG; Parkinson, FE; Sinclair, CJ; Young, JD | 1 |
| Baranyi, M; Dóda, M; Haskó, G; Sperlágh, B | 1 |
| Cohn, CA; Heckl, WM; Holm, NG; Sowerby, SJ | 1 |
| Abe, Y; Fujisawa, Y; Fukui, T; He, H; Kimura, S; Miura, K; Nishiyama, A; Rahman, M | 1 |
| Winter, D; Zubay, G | 1 |
| Bohr, VA; Dianov, GL; Nyaga, SG; Souza-Pinto, N; Stevnsner, T; Thybo, T | 1 |
| Amillis, S; Diallinas, G; Koukaki, M | 1 |
| Barsotti, C; Ipata, PL; Tozzi, MG | 1 |
| Bain, D; Castro, M; Fairbanks, LD; Larregina, A; Lowenstein, P; Morelli, A; Simmonds, HA; Southgate, T | 1 |
| Gasic, JM; Isakovic, AJ; Markovic, ID; Rakic, LM; Rakic, MLj; Redzic, ZB; Segal, MB; Thomas, SA | 1 |
| Holm, NG; Petersen, GB; Sowerby, SJ | 1 |
| Bohr, VA; de Souza-Pinto, NC; Stevnsner, T | 1 |
| Andrew, CM; Ciccarelli, R; Crocker, CE; Di Iorio, P; Kleywegt, S; Rathbone, MP; Traversa, U; Werstiuk, ES | 1 |
| Candlish, D; De Koning, HP; Wallace, LJ | 1 |
| Ayres, BE; Imura, H; Suleiman, MS | 1 |
| Chen, YH; Huang, XL; Li, LQ; Zhang, HY | 1 |
| Al-Salabi, MI; De Koning, HP; Wallace, LJ | 1 |
| DUNCAN, RE; SETTERFIELD, G | 1 |
| JORGENSEN, S | 1 |
| GREGOIRE, J | 1 |
| BLAIR, AE; LASTER, L; SEEGMILLER, JE; WYNGAARDEN, JB | 1 |
| WHITTAM, R | 1 |
| ARAS, AJ; BECKER, M; BROWN, AL; HASS, GM | 1 |
| BIEBER, AL; CHANG, PK; FISCHER, GA; SARTORELLI, AC | 1 |
| DEMAIN, AL | 1 |
| AMMANN, EC; LYNCH, VH | 1 |
| HENDESS, RW; TAYLOR, EC | 1 |
| Self, WT; Stadtman, TC; Wolfe, MD | 1 |
| Barrett, MP; Brun, R; Burchmore, RJ; de Koning, HP; Enyaru, JC; Geiser, F; Kaminsky, R; Mäser, P; Matovu, E; Seebeck, T; Stewart, ML; Wallace, LJ | 1 |
| Bryant, RE; Crawford, CR | 1 |
| Amillis, S; Cecchetto, G; Diallinas, G; Drevet, C; Scazzocchio, C | 1 |
| Cheng, BM; Guo, FQ; Huang, LF; Liang, YZ; Zhou, ZF | 1 |
| Aamodt, RM; Bjørås, M; Falnes, PØ; Johansen, RF; Seeberg, E | 1 |
| Gaeva, EB; Kornienko, IV; Narezhnaia, EV | 1 |
| Rappaport, HP | 1 |
| SHAW, E | 1 |
| Leoncini, R; Marinello, E; Porcelli, B; Resconi, G; Terzuoli, L; Vannoni, D | 1 |
| Bench, G; Birck, MR; Evans, GB; Furneaux, RH; Kim, K; Lewandowicz, A; Madrid, DC; Mwakingwe, A; Ringia, EA; Schramm, VL; Shi, W; Singh, V; Ting, LM; Tyler, PC | 1 |
| Lescoute, A; Westhof, E | 1 |
| Roberts, EL | 1 |
| Akaike, T; Kato, R; Maeda, T; Tamai, I | 1 |
| Adhikari, S; Roy, R; Toretsky, JA; Yuan, L | 1 |
| Rolfes, RJ | 1 |
| Dietz, C; Fairbanks, L; Henkel, R; Löeffler, M; Niemeyer, T; Schroeder-Printzen, I | 1 |
| Cecchetto, G; Diallinas, G; Drevet, C; Hatzinikolaou, DG; Lemuh, ND; Pantazopoulou, A; Scazzocchio, C | 1 |
| Bentancor, L; Iribarren, AM; Lewkowicz, ES; Porro, S; Schoijet, A; Sinisterra, JV; Trelles, JA | 1 |
| Herdewijn, P; Lagoja, IM | 1 |
| Gao, JL; Hu, LF; Jiang, ZH; Lai, CM; Leung, KS; Li, SP; Lu, GH; Wang, YT; Yu, ZL | 1 |
| Albalos, M; Battersby, TR; Friesenhahn, MJ | 1 |
| Parry, TE | 1 |
| Bröer, S; Downie, MJ; Howitt, SM; Kirk, K; Saliba, KJ | 1 |
| Dencic, SM; Isakovic, AJ; Redzic, ZB; Segal, MB | 1 |
| Chen, J; Deng, T; Du, G; Liao, X; Zhu, Y | 1 |
| Matsika, S; Mburu, E | 1 |
| Almendros, M; Carlos, JB; Gago, JV | 1 |
| Koch, HP; Landfear, SM; Larsson, HP; Ortiz, D; Sanchez, MA | 1 |
| Adhikari, S; Roy, R; Uren, A | 1 |
| Hunter, CN; McLean, S | 1 |
| Balaram, H; Bopanna, MP; Bulusu, V; Mehrotra, S | 1 |
| Barks, HL; Buckley, R; Di Mauro, E; Grieves, GA; Hud, NV; Orlando, TM | 1 |
| Alexandrova, AN | 1 |
| Arakawa, C; Dairi, T; Furihata, K; Hiratsuka, T; Itoh, N; Kuratsu, M; Seto, H | 1 |
| Li, HM; Li, YY; Liu, P; Tang, YJ; Wan, DJ | 1 |
| Cho, BK; Embree, M; Federowicz, SA; Kim, D; Palsson, BØ; Park, YS | 1 |
| Chi, Y; Lu, D; Luo, F; Wu, H | 1 |
| Fu, WW; Jia, YR; Liu, P; Sun, LX; Sun, MY; Zhang, WM | 1 |
| Byram, R; Jain, S; Jewett, MW; Rosa, PA; Sutchu, S | 1 |
| Amillis, S; Diallinas, G; Kosti, V; Krypotou, E; Mikros, E; Myrianthopoulos, V | 1 |
| Chen, CP; Dupradeau, FY; Gray, BD; Sanders, JM; Sethi, D; Singh, A; Thakur, ML; Wampole, ME; Wang, F; Wickstrom, E | 1 |
| Chen, CH; Lin, MS; Lin, YT | 1 |
| Baronian, K; Bode, R; Cordes, A; Hoferichter, P; Jankowska, D; Klein, C; Kunze, G; Matros, A; Mock, HP; Trautwein-Schult, A | 1 |
| Christoffersen, S; Hansen, MR; Jensen, KF; Jensen, KS; Kadziola, A; Rasmussen, MS | 1 |
| Dimandja, JM; Jeilani, YA; Newallo, D; Nguyen, HT; Nguyen, MT | 1 |
| Song, JP; Zhu, M | 1 |
| Cui, JW; Gao, GG; Li, JL; Qiu, HB; Wu, DM; Xu, GB | 1 |
| Brinkmann, NR; Cantrell, WA; Dawley, MM; Denifl, S; Plattner, P; Ptasińska, S; Scheier, P; Tanzer, K | 1 |
| Eng, WS; Guddat, LW; Keough, DT; Pohl, R; Poštová Slavětínská, L; Rejman, D | 1 |
| Furukawa, J; Inoue, K; Kanai, Y; Maeda, J; Matsuo, H; Ohta, K; Takada, T; Yasujima, T; Yuasa, H | 1 |
| Chen, Y; Huang, BL; Huang, LY; Lin, SE; Zheng, LH | 1 |
| Bacher, M; Chiang, YM; Faehnrich, B; Hellinger, R; Kluger, B; Rychli, K; Strauss, J; Wagner, M; Zutz, C | 1 |
| Benner, SA; Kim, HJ | 1 |
| Alzahrani, KJ; Campagnaro, GD; De Koning, HP; Munday, JC | 1 |
| Hornum, M; Kumar, P; Nielsen, P; Nielsen, RB; Petersen, M; Sharma, PK; Stendevad, J | 1 |
| Kouchi, A; Naraoka, H; Oba, Y; Takano, Y; Watanabe, N | 1 |
| Botou, M; Charalambous, V; Flemetakis, E; Frillingos, S; Lazou, P; Mikros, E; Papakostas, K; Yalelis, V; Zantza, I | 1 |
| Angelov, I; Dincheva, I; Enchev, V; Markova, N; Rangelov, M; Slavova, S; Stoyanova, N | 1 |
| Cabaj, MK; Dominiak, PM | 1 |
| Dong, K; Gong, Y; Jiang, D; Oger, P; Zhang, L | 1 |
| Hosoyamada, M; Shibata, S; Tomioka, NH; Uchida, S; Watanabe, T; Yasuno, N | 1 |
| Abramov, G; Pozdnyakova, Y; Shakeev, K; Shestakov, D; Tankibaeva, N; Tusupbekova, M | 1 |
5 review(s) available for adenine and hypoxanthine
| Article | Year |
|---|---|
Purine salvage pathways in myocardium.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine; Adenosine Kinase; Adenosine Monophosphate; Animals; Guanine; Guanosine; Guanosine Monophosphate; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Inosine Monophosphate; Myocardium; Purine Nucleosides; Purine Nucleotides | 1985 |
Nucleoside and nucleobase transport in animal cells.
Topics: Adenine; Algorithms; Animals; Biological Transport; Dilazep; Dipyridamole; Hypoxanthine; Hypoxanthines; Kinetics; Lidoflazine; Monosaccharide Transport Proteins; Nucleosides; Temperature; Thioinosine; Thionucleosides | 1988 |
Base excision repair in nuclear and mitochondrial DNA.
Topics: Adenine; Aging; Animals; Base Sequence; Cell Line; Cell Nucleus; Cell-Free System; DNA; DNA Damage; DNA Glycosylases; DNA Polymerase beta; DNA Repair; DNA-Formamidopyrimidine Glycosylase; DNA, Mitochondrial; Guanine; Hypoxanthine; Lymphocytes; Mammals; Mice; Mitochondria; Molecular Sequence Data; N-Glycosyl Hydrolases; Oxidants; Oxidation-Reduction; Oxidative Stress; Point Mutation; Proliferating Cell Nuclear Antigen; Rats; Thymine | 2001 |
Riboswitch structures: purine ligands replace tertiary contacts.
Topics: Adenine; Base Pairing; Crystallography, X-Ray; Guanine; Hypoxanthine; Ligands; Nucleic Acid Conformation; Purines; Regulatory Sequences, Ribonucleic Acid; RNA | 2005 |
On the mutagenic action of adenine.
Topics: Adenine; Cytosine; Deamination; DNA; Humans; Hypoxanthine; Mutagenesis; Point Mutation | 2007 |
232 other study(ies) available for adenine and hypoxanthine
| Article | Year |
|---|---|
Rational Design of Selective Adenine-Based Scaffolds for Inactivation of Bacterial Histidine Kinases.
Topics: Adenine; Adenosine Triphosphate; Anti-Bacterial Agents; Aspartic Acid; Bacteria; Drug Design; Histidine Kinase; HSP90 Heat-Shock Proteins; Models, Molecular; Molecular Docking Simulation; Structure-Activity Relationship | 2017 |
Structure-activity relationships in fungal nucleobases transporters as dissected by the inhibitory effects of novel purine analogues.
Topics: Antifungal Agents; Aspergillosis; Aspergillus nidulans; Biological Transport; Drug Design; Fungal Proteins; Humans; Molecular Docking Simulation; Nucleobase Transport Proteins; Purines; Structure-Activity Relationship | 2018 |
De novo purine ribonucleotide biosynthesis in adult Angiostrongylus cantonensis (Nematoda: Metastrongyloidea).
Topics: Adenine; Adenosine; Angiostrongylus; Animals; Female; Guanine; Hypoxanthine; Hypoxanthines; Inosine; Kinetics; Male; Metastrongyloidea; Purine Nucleotides | 1979 |
Contrast in adenine uptake by chicken and rabbit erythrocytes in vitro.
Topics: Adenine; Adenine Nucleotides; Adenine Phosphoribosyltransferase; Animals; Blood Proteins; Cell Membrane Permeability; Chickens; Chromatography, Thin Layer; Erythrocytes; Guanine; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Phosphoribosyl Pyrophosphate; Rabbits; Temperature | 1992 |
Purine-cytosine permease of Saccharomyces cerevisiae. Effect of external pH on nucleobase uptake and binding.
Topics: Adenine; Biological Transport; Carrier Proteins; Cell Membrane; Chromosome Deletion; Cloning, Molecular; Cytosine; Genes, Fungal; Hydrogen-Ion Concentration; Hypoxanthine; Hypoxanthines; Kinetics; Ligands; Membrane Transport Proteins; Nucleobase Transport Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 1992 |
Purification and substrate inactivation of xanthine dehydrogenase from Chlamydomonas reinhardtii.
Topics: Acetaldehyde; Adenine; Animals; Chlamydomonas reinhardtii; Enzyme Activation; Hypoxanthine; Hypoxanthines; NAD; NADP; Spectrophotometry; Xanthine; Xanthine Dehydrogenase; Xanthines | 1992 |
Changes in serum and urinary uric acid levels in normal human subjects fed purine-rich foods containing different amounts of adenine and hypoxanthine.
Topics: Adenine; Adult; Diet; Food Analysis; Glycine max; Humans; Hypoxanthine; Hypoxanthines; Liver; Male; Middle Aged; Purines; Uric Acid | 1992 |
Absorption and metabolism of purines by the lower intestine of the chicken.
Topics: Adenine; Animals; Chickens; Guanine; Hypoxanthine; Hypoxanthines; Intestinal Absorption; Intestinal Mucosa; Intestines; Male; Purines; Uric Acid; Xanthine; Xanthines | 1991 |
Dynamics of the dATP pool in cultured mammalian cells.
Topics: 3T3 Cells; Adenine; Animals; Aphidicolin; Cell Line; Cytarabine; Deoxyadenine Nucleotides; Deoxyadenosines; DNA; Hypoxanthine; Hypoxanthines; Kinetics; Mice; Pentostatin; Substrate Cycling; Thymine Nucleotides | 1992 |
Purine metabolites and pyrimidine bases in cerebrospinal fluid of children with simple febrile seizures.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Child, Preschool; Cytosine; Female; Guanine; Guanosine; Humans; Hypoxanthine; Hypoxanthines; Infant; Inosine; Inosine Monophosphate; Male; Purines; Pyrimidine Nucleosides; Seizures, Febrile; Thymine; Uracil; Uric Acid; Xanthine; Xanthines | 1991 |
Adenine and hypoxanthine transport in human erythrocytes: distinct substrate effects on carrier mobility.
Topics: Adenine; Biological Transport; Carrier Proteins; Erythrocytes; Humans; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Kinetics; Reference Values; Substrate Specificity | 1991 |
Adenine nucleotide catabolism in the erythrocytes of uraemic patients.
Topics: Adenine; Adenine Nucleotides; AMP Deaminase; Anemia; Erythrocytes; Humans; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Iodoacetates; Iodoacetic Acid; Kinetics; Uremia | 1991 |
Hypoxanthine depletion induced by xanthine oxidase inhibits malaria parasite growth in vitro.
Topics: Adenine; Adenosine Triphosphate; Animals; Carbon Radioisotopes; Catalase; Chloroquine; Erythrocytes; Glycine; Humans; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Kinetics; Plasmodium falciparum; Purines; Superoxide Dismutase; Xanthine Oxidase | 1991 |
Selective in vitro inhibition of human MOLT-4 T lymphoblasts by the novel purine nucleoside phosphorylase inhibitor, CI-972.
Topics: Adenine; Cell Division; Deoxycytidine; Deoxyguanine Nucleotides; DNA Replication; Guanosine Triphosphate; Humans; Hypoxanthine; Hypoxanthines; Kinetics; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Purine-Nucleoside Phosphorylase; Pyrimidines; T-Lymphocytes; Thiophenes | 1991 |
A novel mechanism of mycophenolic acid resistance in the protozoan parasite Tritrichomonas foetus.
Topics: Adenine; Animals; Cloning, Molecular; Drug Resistance; Guanine; Guanine Nucleotides; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; IMP Dehydrogenase; Ketone Oxidoreductases; Mutation; Mycophenolic Acid; Tritrichomonas; Xanthine; Xanthines | 1990 |
The effect of nutritional state and allopurinol on nucleotide formation in enterocytes from the guinea pig small intestine.
Topics: Adenine; Adenine Phosphoribosyltransferase; Allopurinol; Animals; Biological Transport; Fasting; Food; Guanine; Guanosine; Guinea Pigs; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Inosine; Inosine Monophosphate; Intestinal Mucosa; Intestine, Small; Male; Nucleotides; Xanthine Oxidase | 1991 |
Degradation of adenine nucleotides in the erythrocytes of patients with chronic renal failure.
Topics: Adenine; Adenine Nucleotides; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Erythrocytes; Humans; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Kidney Failure, Chronic; Reference Values | 1990 |
Sequential decrease in platelet energy charge after hepatic resection in cirrhotics.
Topics: Adenine; Adenosine Triphosphate; Aged; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Blood Platelets; Carcinoma, Hepatocellular; Critical Care; Energy Metabolism; Female; Hepatectomy; Humans; Hypoxanthine; Hypoxanthines; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Platelet Count | 1990 |
Effects of glucose and adenosine on the ATP content of hamster spermatids.
Topics: Adenine; Adenosine; Adenosine Kinase; Adenosine Triphosphate; Animals; Cricetinae; Cyclic AMP; Dipyridamole; Dose-Response Relationship, Drug; Fructose; Galactose; Glucose; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Male; Mannose; Spermatids; Tubercidin | 1990 |
Purine levels and metabolism in human follicular fluid.
Topics: Adenine; Adenosine; Adult; Chorionic Gonadotropin; Chromatography, High Pressure Liquid; Cyclic AMP; Female; Follicular Fluid; Humans; Hypoxanthine; Hypoxanthines; Inosine; Kinetics; Menotropins; Oocytes; Ovary; Purines | 1990 |
Adenine nucleotide depletion from endothelial cells exposed to xanthine oxidase.
Topics: Adenine; Adenine Nucleotides; Carbon Radioisotopes; Cells, Cultured; Endothelium, Vascular; Humans; Hypoxanthine; Hypoxanthines; Kinetics; Radioisotope Dilution Technique; Xanthine Oxidase | 1990 |
Biochemical basis of the prevention of 6-thiopurine toxicity by the nucleobases, hypoxanthine and adenine.
Topics: 2-Aminopurine; Adenine; Adenine Phosphoribosyltransferase; Antineoplastic Agents; Biological Transport; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Inosine Monophosphate; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Promyelocytic, Acute; Mercaptopurine; Thioguanine; Thionucleotides; Tumor Cells, Cultured | 1990 |
Influence of hypoxanthine, allopurinol and adenine on resistance of rats and hamsters to hypobaric hypoxia.
Topics: Adenine; Allopurinol; Animals; Cricetinae; Female; Hypoxanthine; Hypoxanthines; Hypoxia; Rats; Rats, Inbred Strains; Xanthine Oxidase | 1990 |
Partial purification of an adenine-dependent serum factor which retards the reactivation of lens epithelial cells in primary culture by inhibiting protein synthesis and cell spreading.
Topics: Adenine; Animals; Cattle; Cell Adhesion; Cells, Cultured; Drug Synergism; Epithelium; Eye Proteins; Growth Inhibitors; Guanine; Hypoxanthine; Hypoxanthines; Lens, Crystalline; Protein Synthesis Inhibitors | 1990 |
Metabolism and salvage of adenine and hypoxanthine by myocytes isolated from mature rat heart.
Topics: Adenine; Adenine Nucleotides; Adenosine Triphosphate; Animals; Enzymes; Guanosine Monophosphate; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine Monophosphate; Myocardium; Phosphoribosyl Pyrophosphate; Rats; Ribose | 1985 |
Purine nucleotide metabolism in resident and activated rat macrophages in vitro.
Topics: Adenine; Adenosine; Animals; Cells, Cultured; Guanine; Guanosine; Hypoxanthine; Hypoxanthines; Inosine; Macrophage Activation; Macrophages; Pentosephosphates; Phosphoribosyl Pyrophosphate; Purine Nucleotides; Rats; Thioglycolates | 1985 |
Usefulness of intact erythrocyte studies in the diagnosis of inherited purine and pyrimidine defects.
Topics: Adenine; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Deoxyadenosines; Erythrocytes; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Orotic Acid; Phosphoribosyl Pyrophosphate; Purine-Pyrimidine Metabolism, Inborn Errors; Radioisotope Dilution Technique | 1986 |
Differential effect of isoprinosine on lymphocyte proliferation: comparison of two tissue culture media.
Topics: Adenine; Adult; Culture Media; Humans; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Inosine Pranobex; Lymphocyte Activation; Middle Aged; Phytohemagglutinins | 1986 |
Purine nucleotide metabolism in phytohemagglutinin-induced human T lymphocytes.
Topics: Adenine; Adenine Nucleotides; DNA; Guanine; Guanine Nucleotides; Humans; Hypoxanthine; Hypoxanthines; Inosine Monophosphate; Pentosephosphates; Phosphoribosyl Pyrophosphate; Phytohemagglutinins; Purine Nucleotides; RNA; T-Lymphocytes | 1987 |
Matrix-isolation of H-induced free radicals from purines in acidic glasses.
Topics: Adenine; Electron Spin Resonance Spectroscopy; Free Radicals; Glass; Guanine; Hydrogen; Hypoxanthine; Hypoxanthines; Purines; Sulfuric Acids; Xanthine; Xanthines | 1989 |
Expression of a novel high affinity purine base transport system in mutant mouse S49 cells does not require a functional nucleoside transporter.
Topics: Adenine; Animals; Biological Transport; Clone Cells; Dipyridamole; Dose-Response Relationship, Drug; Gene Expression; Guanine; Hybridization, Genetic; Hypoxanthine; Hypoxanthines; Inosine; Lymphoma; Mice; Mice, Inbred BALB C; Mutation; Phenotype; T-Lymphocytes; Thioinosine; Tumor Cells, Cultured | 1989 |
Adenine uptake by human erythrocytes.
Topics: Adenine; Biological Transport; Erythrocytes; Humans; Hypoxanthine; Hypoxanthines; Xanthine Oxidase | 1989 |
AMP deaminase and thymidine kinase deficiencies in a mutant mouse S49 cell clone.
Topics: Adenine; AMP Deaminase; Animals; Cell Division; Clone Cells; Dose-Response Relationship, Drug; Hybrid Cells; Hypoxanthine; Hypoxanthines; Lymphoma; Mice; Mice, Inbred BALB C; Nucleotide Deaminases; Thymidine; Thymidine Kinase; Tumor Cells, Cultured | 1989 |
[The pool of free purine and pyrimidine nucleosides and bases in the thymocytes, and splenic T- and B-lymphocytes of C3HA mice during the growth of solid hepatoma 22a].
Topics: Adenine; Adenosine; Animals; B-Lymphocytes; Deoxycytidine; DNA, Neoplasm; Guanine; Hypoxanthine; Hypoxanthines; Inosine; Liver Neoplasms, Experimental; Mice; Mice, Inbred C3H; Purine Nucleosides; Pyrimidine Nucleosides; Spleen; T-Lymphocytes; Thymus Gland; Time Factors; Xanthine; Xanthines | 1989 |
Characterization of solution-phase and gas-phase reactions in on-line electrochemistry-thermospray tandem mass spectrometry.
Topics: Adenine; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Electrochemistry; Gases; Hypoxanthine; Hypoxanthines; Mass Spectrometry; Mercaptopurine; Purines; Solutions | 1989 |
Alterations of purine metabolism in mononuclear cells of individuals at risk of developing type I (insulin-dependent) diabetes mellitus.
Topics: Adenine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adolescent; Adult; Child; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Female; Glucose Tolerance Test; Humans; Hypoxanthine; Hypoxanthines; Male; Phagocytes; Risk Factors; Time Factors | 1989 |
The effects of base analogue substitutions on the cleavage by the EcoRI restriction endonuclease of octadeoxyribonucleotides containing modified EcoRI recognition sequences.
Topics: Adenine; Base Sequence; Binding Sites; Cytosine; Deoxyribonuclease EcoRI; DNA Restriction Enzymes; Guanine; Hydrolysis; Hypoxanthine; Hypoxanthines; Kinetics; Methylation; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Structure-Activity Relationship; Temperature; Thymine | 1986 |
Hypoxanthine transport through human erythrocyte membranes.
Topics: Adenine; Biological Transport; Erythrocyte Membrane; Humans; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine Monophosphate; Phosphates; Receptors, Cell Surface | 1986 |
Genetic demonstration of bidirectionality in the high affinity purine base transporter of mutant mouse S49 cells.
Topics: Adenine; Adenosine Monophosphate; Animals; Azaserine; Carrier Proteins; Cell Line; Guanosine Monophosphate; Hypoxanthine; Hypoxanthines; Inosine Monophosphate; Membrane Proteins; Mice; Mutation; Nucleoside Transport Proteins | 1987 |
Functional and mechanistic studies on the toxicity of deoxyguanosine for the in vitro proliferation and differentiation of human peripheral blood B lymphocytes.
Topics: Adenine; B-Lymphocytes; Cell Cycle; Cell Differentiation; Cells, Cultured; Deoxycytidine; Deoxyguanosine; Deoxyribonucleotides; Humans; Hypoxanthine; Hypoxanthines; Lymphocyte Activation; Purine-Nucleoside Phosphorylase; Staphylococcus aureus | 1986 |
Adenosine accumulation in Saccharomyces cerevisiae cultured in medium containing low levels of adenine.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Monophosphate; Aspergillus; Chromatography, High Pressure Liquid; Hypoxanthine; Hypoxanthines; Inosine; Models, Chemical; Purine-Nucleoside Phosphorylase; Saccharomyces cerevisiae | 1986 |
Hypoxanthine and xanthine in stored SAGM-blood.
Topics: Adenine; Blood Preservation; Glucose; Humans; Hypoxanthine; Hypoxanthines; Mannitol; Sodium Chloride; Time Factors; Xanthine; Xanthines | 1986 |
7-Deaza-9-phenyladenines. A new class of adenosine receptor antagonists.
Topics: Adenine; Adenosine; Animals; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Rats; Receptors, Purinergic; Structure-Activity Relationship | 1988 |
Myocardial reperfusion injury. Role of myocardial hypoxanthine and xanthine in free radical-mediated reperfusion injury.
Topics: Adenine; Adenine Nucleotides; Animals; Coronary Disease; Dogs; Female; Free Radicals; Heart; Heart Ventricles; Hypoxanthine; Hypoxanthines; Male; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; Thioinosine; Xanthine; Xanthines | 1988 |
Pathways of purine nucleotide synthesis in the human trophoblast early and late in gestation.
Topics: Adenine; Adenosine Triphosphate; Cells, Cultured; Female; Humans; Hypoxanthine; Hypoxanthines; Pregnancy; Purine Nucleotides; Trophoblasts | 1988 |
Alterations in nucleotide pools induced by 3-deazaadenosine and related compounds. Role of adenylate deaminase.
Topics: Adenine; Adenosine Kinase; Alanine; Aminoglycosides; AMP Deaminase; Animals; Anti-Bacterial Agents; Cell Survival; Coformycin; Hypoxanthine; Hypoxanthines; Mice; Nucleotide Deaminases; Nucleotides; Time Factors; Tubercidin | 1988 |
Purine nucleobase transport in human erythrocytes. Reinvestigation with a novel "inhibitor-stop" assay.
Topics: Adenine; Biological Transport; Erythrocytes; Guanine; Humans; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Kinetics; Papaverine | 1988 |
Acyclovir transport into human erythrocytes.
Topics: Acyclovir; Adenine; Biological Transport; Carbon Radioisotopes; Erythrocytes; Guanine; Humans; Hypoxanthine; Hypoxanthines; Idoxuridine; Iodine Radioisotopes; Kinetics; Nucleosides; Purines; Pyrimidines; Sucrose; Tritium | 1988 |
Effect of nutritional state and allopurinol on purine metabolism in the rat small intestine.
Topics: Adenine; Allopurinol; Animals; Eating; Fasting; Guanine; Hypoxanthine; Hypoxanthines; Inosine; Intestine, Small; Male; Nutritional Status; Purines; Rats; Rats, Inbred Strains | 1988 |
A graphical method for determining inhibition parameters for partial and complete inhibitors.
Topics: Adenine; Adenosine Triphosphate; Enzyme Inhibitors; Hypoxanthine; Hypoxanthines; Kinetics; Methods; Models, Biological; N-Glycosyl Hydrolases | 1987 |
Role of the nucleoside transport function in the transport and salvage of purine nucleobases.
Topics: Adenine; Animals; Antimetabolites, Antineoplastic; Azaserine; Biological Transport; Cell Line; Dipyridamole; Hypoxanthine; Hypoxanthines; Mice; Nucleosides; Purines; T-Lymphocytes; Thioinosine | 1986 |
Pathways of adenine nucleotide catabolism in human erythrocytes.
Topics: Adenine; Adenine Nucleotides; Adenosine; Blood Glucose; Coformycin; Erythrocytes; Humans; Hydrogen-Ion Concentration; Hypoxanthine; Hypoxanthines; Pentostatin; Phosphates; Tubercidin | 1986 |
Expression of a novel high-affinity purine nucleobase transport function in mutant mammalian T lymphoblasts.
Topics: Adenine; Animals; Azaserine; Biological Transport, Active; Cell Line; Dipyridamole; Guanine; Hypoxanthine; Hypoxanthines; Kinetics; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Mutation; Phenotype; Purine Nucleosides; T-Lymphocytes; Thioinosine | 1986 |
O6-methylguanine specifically induces AT----GC transition mutations.
Topics: 5-Methylcytosine; Adenine; Alkylation; Base Composition; Cytosine; DNA Damage; DNA, Bacterial; Escherichia coli; Guanine; Hypoxanthine; Hypoxanthines; Mutation | 1987 |
Expression of the high-affinity purine nucleobase transporter in mutant mouse S49 cells does not require a functional wild-type nucleoside-nucleobase transporter.
Topics: Adenine; Animals; Carrier Proteins; Cell Division; Cell Line; Guanine; Hypoxanthine; Hypoxanthines; Kinetics; Membrane Proteins; Membrane Transport Proteins; Mice; Mutation; Nucleobase Transport Proteins; Nucleoside Transport Proteins; Nucleosides; Phenotype | 1987 |
Effect of testosterone on purine synthesis de novo in rat perineal muscle in vivo.
Topics: Adenine; Animals; Carbon Radioisotopes; Formates; Guanine; Hypoxanthine; Hypoxanthines; Male; Muscle, Smooth; Muscles; Orchiectomy; Purines; Rats; Rats, Inbred Strains; Sexual Maturation; Testosterone | 1987 |
Hypoxanthine transport through the blood-brain barrier.
Topics: Adenine; Animals; Blood-Brain Barrier; Hypoxanthine; Hypoxanthines; Inosine; Leucine; Probenecid; Rats; Rats, Inbred Strains; Theophylline; Thiamine; Uracil | 1987 |
Liquid chromatography with multichannel ultraviolet detection used for studying disorders of purine metabolism.
Topics: Adenine; Allopurinol; Chromatography, High Pressure Liquid; Humans; Hypoxanthine; Hypoxanthines; Inosine; Oxypurinol; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Spectrophotometry, Ultraviolet; Uric Acid; Uridine; Xanthine; Xanthines | 1987 |
Guanine is a growth factor for Legionella species.
Topics: Adenine; Culture Media; Cytosine; Growth Substances; Guanine; Hydrogen-Ion Concentration; Hypoxanthine; Hypoxanthines; Legionella; Nucleosides; Nucleotides; Thymine; Uracil; Xanthine; Xanthines | 1986 |
Adenosine export from the liver: oxygen dependency.
Topics: Adenine; Adenosine; Animals; Bicarbonates; Blood Substitutes; Chromatography, High Pressure Liquid; Fluorocarbons; Hypoxanthine; Hypoxanthines; Liver; Male; Oxygen; Perfusion; Purines; Rats; Rats, Inbred Strains | 1986 |
Hypoxanthine and adenine metabolism in bovine thyroid tissue.
Topics: Adenine; Adenine Phosphoribosyltransferase; Animals; Cattle; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; In Vitro Techniques; Kinetics; Spectrophotometry, Infrared; Thyroid Gland; Xanthine Oxidase | 1986 |
Purine metabolism in human neuroblastoma cell lines.
Topics: Adenine; Adenosine; Cell Line; Guanosine; Humans; Hypoxanthine; Hypoxanthines; Neuroblastoma; Nucleosides; Purine Nucleosides; Purine Nucleotides; Purines; Tubercidin | 1986 |
Purine salvage in rat heart myoblasts.
Topics: Adenine; Adenosine; Animals; Biological Transport; Hypoxanthine; Hypoxanthines; Inosine; Myocardium; Phosphates; Purine Nucleotides; Purines; Rats | 1986 |
Effect of dipyridamole on adenine incorporation into hypoxanthine nucleotides of fresh red blood cells.
Topics: Adenine; Biological Transport; Carbon Radioisotopes; Dipyridamole; Erythrocytes; Humans; Hypoxanthine; Hypoxanthines; Inosine Monophosphate; Inosine Nucleotides | 1986 |
Release of endogenous and radioactive purines from the rabbit retina.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Animals; Dipyridamole; Evoked Potentials; Female; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Male; Potassium; Purines; Rabbits; Retina; Tritium | 1986 |
Nucleoside and nucleobase transport and metabolism in wild type and nucleoside transport-deficient Aedes albopictus cells.
Topics: Adenine; Adenosine Triphosphate; Aedes; Animals; Biological Transport; Carrier Proteins; Hypoxanthine; Hypoxanthines; Kinetics; Membrane Proteins; Mutation; Nucleoside Transport Proteins; Nucleosides; Thioinosine; Thymidine; Uracil; Uridine | 1987 |
Hereditary xanthinuria. Evidence for enhanced hypoxanthine salvage.
Topics: Adenine; Adenine Nucleotides; Adolescent; Adult; Female; Fructose; Guanosine; Humans; Hypoxanthine; Hypoxanthines; Male; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Uric Acid; Xanthine; Xanthine Oxidase; Xanthines | 1987 |
Identification of hypoxanthine transport and xanthine oxidase activity in brain capillaries.
Topics: Adenine; Allopurinol; Animals; Biological Transport; Blood-Brain Barrier; Brain; Brain Ischemia; Capillaries; Cerebral Cortex; Hypoxanthine; Hypoxanthines; Kinetics; Rats; Uric Acid; Xanthine; Xanthine Oxidase; Xanthines | 1985 |
S49 mouse lymphoma cells are deficient in hypoxanthine transport.
Topics: Adenine; Animals; Biological Transport; Cell Line; Cricetinae; Cricetulus; Dipyridamole; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Lymphoma; Methotrexate; Mice; Permeability; Thymidine; Uridine; Uridine Kinase | 1986 |
On the mechanism of action of free purine bases on DNA synthesis in serum-starved L-cells treated with platelet extract.
Topics: Adenine; Adenosine Triphosphate; Animals; Blood; Blood Platelets; Cell Extracts; Cell Line; Culture Media; DNA; DNA Replication; Fibroblasts; Flow Cytometry; Hot Temperature; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Mice; Purines; Tissue Extracts | 1985 |
Erythroid induction of K562 human leukemia cells: enhancement by purines.
Topics: Adenine; Cell Cycle; Cell Division; Cell Line; Drug Synergism; Guanine; Hemoglobins; Humans; Hypoxanthine; Hypoxanthines; Leukemia; Mycophenolic Acid; Thymidine; Xanthine; Xanthines | 1985 |
Gas chromatographic-mass spectrometric determination of isotopic enrichment of 6-15NH2 in adenine nucleotides.
Topics: Adenine; Adenine Nucleotides; Ammonia; Animals; Gas Chromatography-Mass Spectrometry; Hypoxanthine; Hypoxanthines; Isotope Labeling; Liver; Nitrogen Isotopes; Rats | 1985 |
Magnetic circular dichroism of adenine, hypoxanthine, and guanosine 5'-diphosphate to 180 nm.
Topics: Adenine; Circular Dichroism; DNA; Guanine Nucleotides; Guanosine Diphosphate; Hypoxanthine; Hypoxanthines; Magnetics; Nucleic Acid Conformation; RNA | 1984 |
Mode of action of 2-amino-6-chloro-1-deazapurine.
Topics: 2-Aminopurine; Adenine; AMP Deaminase; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line; Cell Survival; Glycine; Humans; Hypoxanthine; Hypoxanthines; IMP Dehydrogenase; Laryngeal Neoplasms; Leukemia L1210; Macromolecular Substances; Mice; Nucleotides; Ribonucleotides; Structure-Activity Relationship | 1984 |
Approaches to the measurement of intracellular adenine and the discrimination between adenine transport and metabolism in L1210 leukemia cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Animals; Azides; Biological Transport; Glucose; Hypoxanthine; Hypoxanthines; Leukemia L1210; Mice; Phosphates; Temperature; Time Factors | 1982 |
Regulation of de novo purine synthesis in human bone marrow mononuclear cells by hypoxanthine.
Topics: Adenine; Bone Marrow; Bone Marrow Cells; DNA; Guanine; Humans; Hypoxanthine; Hypoxanthines; Leukemia, Myeloid, Acute; Leukocytes; Purines; RNA; Thymine | 1983 |
The regulation of hypoxanthine guanine phosphoribosyl transferase activity through transfer of PRPP by metabolic cooperation.
Topics: Adenine; Animals; Cell Communication; Cell Line; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Mice; Pentosephosphates; Phosphoribosyl Pyrophosphate; Tubercidin | 1984 |
Azathioprine and 6-mercaptopurine (6-MP) suppress the human mixed lymphocyte reaction (MLR) by different mechanisms.
Topics: Adenine; Adenosine; Aminoimidazole Carboxamide; Azathioprine; DNA; Guanine; Humans; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Lymphocyte Culture Test, Mixed; Lymphocytes; Mercaptopurine; Xanthine; Xanthines | 1984 |
Characterization of purine nucleotide metabolism in primary rat cardiomyocyte cultures.
Topics: 5'-Nucleotidase; Adenine; Adenosine; AMP Deaminase; Animals; Carbon Radioisotopes; Cells, Cultured; Fibroblasts; Formates; Humans; Hypoxanthine; Hypoxanthines; Kinetics; Muscles; Myocardium; Nucleotidases; Purine Nucleotides; Rats; Rats, Inbred Strains; Skin; Tritium | 1984 |
The transfer of 5'-methylthioadenosine from B82 cells through the medium to CHW-1102 cells.
Topics: Adenine; Adenosine; Animals; Cell Communication; Cell Line; Cricetinae; Culture Media; Deoxyadenosines; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Mitoguazone; Purine-Nucleoside Phosphorylase; Thionucleosides | 1983 |
Specificity and control of uptake of purines and other compounds in Bacillus subtilis.
Topics: Adenine; Adenosine; Aminoisobutyric Acids; Bacillus subtilis; Biological Transport; Guanine; Guanosine; Guanosine Triphosphate; Hypoxanthine; Hypoxanthines; Inosine; Kinetics; Methylglucosides; Methylglycosides; Purines; Spores, Bacterial; Uracil | 1983 |
Purine biosynthesis de novo in rat skeletal muscle.
Topics: Adenine; Adenosine; Animals; Azaserine; Cycloserine; Female; Formates; Glycine; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Male; Muscles; Purines; Rats; Rats, Inbred Strains; Serine | 1983 |
Ethanol-induced activation of adenine nucleotide turnover. Evidence for a role of acetate.
Topics: Acetates; Acetic Acid; Adenine; Adenine Nucleotides; Adenosine; Adult; Carbon Radioisotopes; Ethanol; Humans; Hypoxanthine; Hypoxanthines; Inosine; Kinetics; Time Factors; Xanthine; Xanthines | 1984 |
A cloning assay for 6-thioguanine resistance provides evidence against certain somatic mutational theories of aging.
Topics: Adenine; Adenine Phosphoribosyltransferase; Aging; Animals; Clone Cells; Drug Resistance; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Kidney; Male; Mice; Mice, Inbred Strains; Muscle Development; Muscles; Mutation; Thioguanine | 1984 |
Adenine pool catabolism in the ischemic, the calcium-depleted ischemic, and the substrate free anoxic isolated rat heart: relationship to contracture development.
Topics: Adenine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Chromatography, High Pressure Liquid; Contracture; Coronary Disease; Energy Metabolism; Hypoxanthine; Hypoxanthines; Hypoxia; Inosine; Inosine Monophosphate; Male; Myocardium; Rats; Rats, Inbred Strains; Uric Acid | 1984 |
Purine metabolism in rat macrophages.
Topics: Adenine; Adenine Nucleotides; Animals; Guanine; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Macrophages; Phosphorylation; Purines; Rats; Xanthine Oxidase | 1984 |
N6-Methyladenosine inhibition of hypoxanthine uptake by Chinese hamster ovary cells.
Topics: Adenine; Adenosine; Animals; Biological Transport; Cells, Cultured; Cricetinae; Cricetulus; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Kinetics | 1983 |
Absorption and metabolism of adenine, adenosine-5'-monophosphate, adenosine and hypoxanthine by the isolated vascularly perfused rat small intestine.
Topics: Absorption; Adenine; Adenosine; Adenosine Monophosphate; Animals; Carbon Radioisotopes; Hypoxanthine; Hypoxanthines; Intestine, Small; Male; Rats; Rats, Inbred Strains | 1984 |
Influence of dietary purines on allopurinol metabolism and allopurinol induced oroticaciduria.
Topics: Adenine; Adenosine; Allopurinol; Diet; Humans; Hypoxanthine; Hypoxanthines; Male; Orotic Acid; Purines | 1984 |
Adenine metabolism in rat skeletal muscle.
Topics: Adenine; Adenosine Triphosphate; Allopurinol; Animals; Electric Stimulation; Hypoxanthine; Hypoxanthines; Muscle Contraction; Muscles; Rats | 1984 |
Purine nucleotide metabolism in primary rat skeletal muscle cultures.
Topics: Adenine; Animals; Carbon Radioisotopes; Cells, Cultured; Embryo, Mammalian; Formates; Guanine; Hypoxanthine; Hypoxanthines; Muscles; Purine Nucleotides; Rats | 1984 |
Leishmania mexicana: purine metabolism in promastigotes, axenic amastigotes, and amastigotes derived from Vero cells.
Topics: Adenine; Adenine Nucleotides; Animals; Cell Line; Chlorocebus aethiops; Guanine; Guanine Nucleotides; Hypoxanthine; Hypoxanthines; Leishmania; Purine Nucleotides | 1984 |
The relationship between purines, pyrimidines, nucleosides, and glutamine for fibroblast cell proliferation.
Topics: Adenine; Adenosine; Animals; Cell Division; Cell Line; DNA; Fibroblasts; Glutamine; Hypoxanthine; Hypoxanthines; Inosine; Mice; Nucleosides; Purines; Pyrimidines | 1984 |
Metabolism of adenosine and 2'-deoxy-adenosine by fetal mouse calvaria in culture.
Topics: Adenine; Adenosine; Animals; Bone and Bones; Culture Media; Deoxyadenosines; Dilazep; Dipyridamole; Hypoxanthine; Hypoxanthines; Inosine; Mice; Organ Culture Techniques | 1982 |
Adenine, the precursor of nucleic acids in intestinal cells unable to synthesize purines de novo.
Topics: Adenine; Animals; Epithelium; Guanine; Hepatectomy; Hypoxanthine; Hypoxanthines; Intestinal Mucosa; Male; Purines; Rats; Xanthine; Xanthines | 1981 |
DNA damage in human respiratory tract epithelial cells: damage by gas phase cigarette smoke apparently involves attack by reactive nitrogen species in addition to oxygen radicals.
Topics: Adenine; Bronchi; Cell Line; DNA; DNA Damage; Epithelium; Guanine; Humans; Hydroxyl Radical; Hypoxanthine; Hypoxanthines; Smoke; Smoking; Xanthine; Xanthines | 1995 |
Induction of kinetochore-containing micronuclei by exogenous O6-methylguanine requires conversion of the methylated base to a nucleotide.
Topics: Adenine; Animals; Cell Line; Cricetinae; Cricetulus; Guanine; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Kinetochores; Methyl Methanesulfonate; Mice; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagens | 1995 |
Breakdown of adenine nucleotides, formation of oxygen free radicals, and early markers of cellular injury in endotoxic shock.
Topics: Adenine; Adenine Nucleotides; Adenosine Triphosphate; Animals; Biomarkers; Blood Pressure; Carbon Dioxide; Creatine; Endotoxins; Energy Metabolism; Escherichia coli Infections; Free Radicals; Hypoxanthine; Hypoxanthines; Lactates; Lipopolysaccharides; Muscles; Oxygen; Phosphocreatine; Platelet Count; Rabbits; Reactive Oxygen Species; Shock, Septic | 1995 |
Altered pyridine metabolism in the erythrocytes of a mentally retarded infant with partial HPRT deficiency.
Topics: Adenine; Carbon Radioisotopes; Child; Erythrocytes; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Infant; Intellectual Disability; Male; NAD; NADP; Purine-Pyrimidine Metabolism, Inborn Errors; Pyrimidines; Radioisotope Dilution Technique; Reference Values; Ribonucleotides | 1994 |
Purine metabolism in female patients with primary gout.
Topics: Adenine; Arthritis, Gouty; Creatinine; Female; Gout; Humans; Hypoxanthine; Hypoxanthines; Male; Purines; Radioisotope Dilution Technique; Reference Values; Sex Characteristics; Uric Acid; Xanthine; Xanthines | 1994 |
Uptake of purine substrates shows major physiological variations in mammalian skin fibroblasts.
Topics: Adenine; Adenoviridae; Animals; Buffaloes; Cell Transformation, Viral; Cells, Cultured; Fibroblasts; Humans; Hypoxanthine; Hypoxanthines; Kinetics; Perissodactyla; Simian virus 40; Skin; Species Specificity | 1995 |
Coculture of astroglial and vascular endothelial cells as apposing layers enhances the transcellular transport of hypoxanthine.
Topics: Adenine; Animals; Biological Transport; Cells, Cultured; Cricetinae; Endothelium, Vascular; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Kinetics; Neuroglia; Temperature | 1995 |
Adenosine is a key component in preservation of ischemically damaged canine pancreas by the two-layer cold storage method.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Cold Temperature; Dogs; Female; Graft Survival; Hypertonic Solutions; Hypoxanthine; Hypoxanthines; Inosine; Ischemia; Kinetics; Male; Organ Preservation; Pancreas; Pancreas Transplantation; Time Factors | 1994 |
Effects of mutational loss of nucleoside kinases on deoxyadenosine 5'-phosphate/deoxyadenosine substrate cycle in cultured CEM and V79 cells.
Topics: Adamantane; Adenine; Adenosine; Adenosine Kinase; Animals; Cell Division; Cell Line; Cricetinae; Deoxyadenosines; Deoxycytidine; Deoxycytidine Kinase; Deoxyribonucleotides; DNA; Fibroblasts; Humans; Hypoxanthine; Hypoxanthines; Kinetics; Lymphocytes; Thymidine; Time Factors; Tritium | 1994 |
Characterization of the alterations in purine nucleotide metabolism in hypoxanthine-guanine phosphoribosyltransferase-deficient rat neuroma cell line.
Topics: Adenine; Adenine Nucleotides; Animals; Formates; Guanine; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Lesch-Nyhan Syndrome; Neuroma; Purine Nucleotides; Rats; Tumor Cells, Cultured; Xanthine; Xanthines | 1993 |
Transport of 5-fluorouracil and uracil into human erythrocytes.
Topics: Adenine; Biological Transport; Erythrocytes; Fluorouracil; Humans; Hypoxanthine; Hypoxanthines; Kinetics; Nucleic Acids; Nucleosides; Papaverine; Tritium; Uracil | 1993 |
Salvage and interconversion of purines in developing Artemia.
Topics: Adenine; Adenine Nucleotides; Adenine Phosphoribosyltransferase; Animals; Artemia; Carbon Radioisotopes; Guanine Nucleotides; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Larva; Purines | 1993 |
Increases in interstitial adenosine and cerebral blood flow with inhibition of adenosine kinase and adenosine deaminase.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Brain; Cerebrovascular Circulation; Dialysis Solutions; Dose-Response Relationship, Drug; Extracellular Space; Hypoxanthine; Hypoxanthines; Inosine; Male; Rats; Rats, Wistar; Tubercidin | 1993 |
Changes in pial arteriolar diameter and CSF adenosine concentrations during hypoxia.
Topics: Adenine; Adenosine; Animals; Arterioles; Cerebrovascular Circulation; Dipyridamole; Hypoxanthine; Hypoxanthines; Hypoxia; Inosine; Male; Pia Mater; Rats; Rats, Sprague-Dawley; Vasodilation | 1993 |
Activity modulation of the fast and slow isozymes of human cytosolic low-molecular-weight acid phosphatase (ACP1) by purines.
Topics: Acid Phosphatase; Adenine; Alleles; Catalysis; Cytosol; Enzyme Activation; Humans; Hypoxanthine; Hypoxanthines; Isoenzymes; Kinetics; Molecular Weight; Purines | 1993 |
Production of a model for Lesch-Nyhan syndrome in hypoxanthine phosphoribosyltransferase-deficient mice.
Topics: Adenine; Adenine Phosphoribosyltransferase; Animals; Brain; Caffeine; Cell Division; Cells, Cultured; Disease Models, Animal; Embryo, Mammalian; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Lesch-Nyhan Syndrome; Mice; Mice, Mutant Strains; Purines; Self-Injurious Behavior; Stem Cells; Thymidine | 1993 |
Concentration of purine compounds in the cerebrospinal fluid of infants suffering from sepsis, convulsions and hydrocephalus.
Topics: Adenine; Bacterial Infections; Chromatography, High Pressure Liquid; Humans; Hydrocephalus; Hypoxanthine; Hypoxanthines; Infant; Infant, Newborn; Inosine; Predictive Value of Tests; Purines; Seizures; Uric Acid; Xanthine; Xanthines | 1995 |
Mice with adenine phosphoribosyltransferase deficiency develop fatal 2,8-dihydroxyadenine lithiasis.
Topics: Adenine; Adenine Phosphoribosyltransferase; Alleles; Allopurinol; Animals; Blotting, Southern; Chromatography, High Pressure Liquid; Cloning, Molecular; Crystallization; Disease Models, Animal; Genotype; Humans; Hypoxanthine; Kidney; Lesch-Nyhan Syndrome; Mice; Mice, Transgenic; Polymerase Chain Reaction; Purines | 1996 |
Diversity of adenine conversion in staphylococci.
Topics: Adenine; Adenine Nucleotides; Ammonia; Hypoxanthine; Species Specificity; Staphylococcus; Staphylococcus epidermidis | 1996 |
Functional analyses of yeast purine-cytosine permease mutants.
Topics: Adenine; Alleles; Amino Acids; Biological Transport; Cell Membrane; Cloning, Molecular; Cytosine; Hypoxanthine; Membrane Transport Proteins; Mutagenesis, Site-Directed; Nucleobase Transport Proteins; Plasmids; Saccharomyces cerevisiae; Sequence Deletion | 1996 |
Adenosine metabolism during phorbol myristate acetate-mediated induction of HL-60 cell differentiation: changes in expression pattern of adenosine kinase, adenosine deaminase, and 5'-nucleotidase.
Topics: 5'-Nucleotidase; Adenine; Adenosine; Adenosine Deaminase; Adenosine Kinase; B-Lymphocytes; Cell Differentiation; Extracellular Space; Gene Expression Regulation, Enzymologic; HL-60 Cells; Humans; Hypoxanthine; Purines; RNA, Messenger; Stress, Physiological; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1997 |
Hypoxanthine uptake at the fetal side of human placenta proceeds through a nucleobase-preferring carrier and a non-saturable process.
Topics: Adenine; Adenosine; Biological Transport; Blood Flow Velocity; Female; Fetus; Guanine; Humans; Hypoxanthine; Papaverine; Placenta; Pregnancy; Sodium; Tritium | 1997 |
Dam methyltransferase from Escherichia coli: kinetic studies using modified DNA oligomers: nonmethylated substrates.
Topics: 2-Aminopurine; Adenine; Base Sequence; DNA Methylation; DNA Probes; DNA, Bacterial; Enzyme Inhibitors; Escherichia coli; Escherichia coli Proteins; Guanine; Hypoxanthine; Kinetics; Molecular Sequence Data; Nucleic Acid Heteroduplexes; Oligonucleotide Probes; Site-Specific DNA-Methyltransferase (Adenine-Specific); Software; Substrate Specificity; Temperature; Thermodynamics; Thymine; Uracil | 1997 |
Validation and steady-state analysis of a power-law model of purine metabolism in man.
Topics: Adenine; Adenine Phosphoribosyltransferase; Guanine; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Kinetics; Models, Biological; Phosphoribosyl Pyrophosphate; Purines; Sensitivity and Specificity; Uric Acid; Xanthine; Xanthines | 1997 |
Models for the regulation of purine metabolism in rat hepatocytes: evaluation of tracer kinetic experiments.
Topics: Adenine; Animals; Carbon Radioisotopes; Cells, Cultured; Guanine; Guanine Nucleotides; Homeostasis; Hypoxanthine; Kinetics; Liver; Male; Mathematics; Models, Biological; Purine Nucleosides; Purines; Radioisotope Dilution Technique; Rats; Rats, Wistar | 1997 |
Adenosine triphosphate degradation products after oxidative stress and metabolic dysfunction in cultured retinal cells.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Cell Hypoxia; Cells, Cultured; Chick Embryo; Enzyme Inhibitors; Glucose; Hypoxanthine; Inosine; Iodoacetates; Iodoacetic Acid; Ischemia; Kinetics; Oligomycins; Oxidative Stress; Retina; Thioinosine | 1997 |
Targeted deletion of alkylpurine-DNA-N-glycosylase in mice eliminates repair of 1,N6-ethenoadenine and hypoxanthine but not of 3,N4-ethenocytosine or 8-oxoguanine.
Topics: Adenine; Animals; Cell-Free System; Cytosine; DNA Glycosylases; DNA Repair; Guanine; Hydrolysis; Hypoxanthine; Mice; Mice, Inbred BALB C; Mice, Knockout; N-Glycosyl Hydrolases; Recombinant Proteins; Substrate Specificity | 1997 |
Purine metabolism and the microaerophily of Helicobacter pylori.
Topics: Adenine; Aminohydrolases; Aminoimidazole Carboxamide; Catalase; Culture Media; Drug Synergism; Free Radical Scavengers; Growth Inhibitors; Helicobacter pylori; Hydrogen Peroxide; Hypoxanthine; Oxygen; Purine Nucleotides; Purines | 1997 |
Structure-based redesign of corepressor specificity of the Escherichia coli purine repressor by substitution of residue 190.
Topics: Adenine; Alanine; Arginine; Bacterial Proteins; Crystallography, X-Ray; Enzyme Repression; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Glutamine; Guanine; Hypoxanthine; Ligands; Mutagenesis, Site-Directed; Protein Conformation; Protein Engineering; Purines; Repressor Proteins | 1998 |
The levels of adenosine and its metabolites in the guinea pig and rat brain during complete ischemia-in vivo study.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Brain; Brain Chemistry; Brain Ischemia; Chromatography, High Pressure Liquid; Dyneins; Enzyme Inhibitors; Guinea Pigs; Hypoxanthine; Inosine; Male; Microwaves; Rats; Rats, Wistar; Spectrophotometry, Ultraviolet; Tissue Fixation | 1998 |
Dual cardiac microdialysis to assess drug-induced changes in interstitial purine metabolites: adenosine deaminase inhibition versus adenosine kinase inhibition.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Chromatography, High Pressure Liquid; Extracellular Space; Hypoxanthine; Inosine; Male; Microdialysis; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Rabbits; Tubercidin | 1998 |
Endothelial purine metabolism and reperfusion injury.
Topics: Adenine; Adenosine; Benzene Derivatives; Cells, Cultured; Endothelium, Vascular; Humans; Hydrogen Peroxide; Hypoxanthine; Kinetics; Oxidants; Phosphocreatine; Purines; Reperfusion Injury; Umbilical Veins | 1998 |
Hypoxanthine, guanine, xanthine phosphoribosyltransferase activity in Cryptosporidium parvum.
Topics: Adenine; Animals; Autoradiography; Binding, Competitive; Cell Line; Cryptosporidium parvum; Dogs; Formates; Glycine; Guanine; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Pentosyltransferases; Spores; Xanthine | 1998 |
Oxidative damage to proteins, lipids, and DNA in cortical brain regions from patients with dementia with Lewy bodies.
Topics: Adenine; Aged; Aged, 80 and over; Alzheimer Disease; Brain Chemistry; Cerebral Cortex; Cytosine; DNA; Guanine; Humans; Hydantoins; Hypoxanthine; Lewy Bodies; Lipid Peroxidation; Middle Aged; Nerve Tissue Proteins; Oxidation-Reduction; Oxidative Stress; Thymine; Uracil; Xanthine | 1998 |
Random population-wide genetic damage induced in replicating cells treated with methotrexate.
Topics: 3T3 Cells; Adenine; Animals; Antimetabolites, Antineoplastic; Cell Cycle; Culture Media; DNA Damage; Folic Acid Antagonists; Hypoxanthine; Methotrexate; Mice; Mutagenicity Tests; Thymidine | 1998 |
Role of the proline residue 376 in the catalytic activity of purine-cytosine permease of Saccharomyces cerevisiae.
Topics: Adenine; Amino Acid Substitution; Blotting, Western; Carrier Proteins; Catalysis; Cell Membrane; Cytosine; Hydrogen-Ion Concentration; Hypoxanthine; Membrane Transport Proteins; Mutagenesis, Site-Directed; Nucleobase Transport Proteins; Proline; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 1998 |
FTIR and UV spectroscopy of parallel-stranded DNAs with mixed A*T/G*C sequences and their A*T/I*C analogues.
Topics: Adenine; Base Composition; Base Sequence; Cytosine; DNA; Guanine; Hot Temperature; Hydrogen Bonding; Hypoxanthine; Inosine; Models, Molecular; Nucleic Acid Denaturation; Nucleic Acid Heteroduplexes; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Thymine | 1998 |
Endogenous adenosine reduces the occurrence of ischemia-induced ventricular fibrillation in rat heart.
Topics: Adenine; Adenosine; Aminoimidazole Carboxamide; Animals; Caffeine; Creatine Kinase; Electrocardiography; Enzyme Inhibitors; Hypoxanthine; Inosine; Male; Myocardial Ischemia; Myocardium; Perfusion; Rats; Rats, Wistar; Reperfusion Injury; Ribonucleosides; Theophylline; Thioinosine; Thiophenes; Time Factors; Ventricular Fibrillation; Xanthines | 1999 |
Screening of an intragenic second-site suppressor of purine-cytosine permease from Saccharomyces cerevisiae. Possible role of Ser272 in the base translocation process.
Topics: Adenine; Amino Acid Sequence; Biological Transport; Carrier Proteins; Cytosine; Hydrogen-Ion Concentration; Hypoxanthine; Kinetics; Membrane Proteins; Membrane Transport Proteins; Molecular Sequence Data; Mutagenesis; Mutation; Nucleobase Transport Proteins; Plasmids; Protein Structure, Secondary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Suppression, Genetic; Transformation, Genetic | 1999 |
The prebiotic synthesis of modified purines and their potential role in the RNA world.
Topics: Adenine; Adenosine; Amines; Amino Acids; Guanine; Hydrogen-Ion Concentration; Hydrolysis; Hypoxanthine; Hypoxanthines; Purines; RNA; Temperature | 1999 |
The type of DNA glycosylase determines the base excision repair pathway in mammalian cells.
Topics: Adenine; Animals; Base Sequence; Cells, Cultured; DNA Glycosylases; DNA Repair; Guanine; HeLa Cells; Humans; Hypoxanthine; Mice; N-Glycosyl Hydrolases | 1999 |
Evidence for a dynamic role for proline376 in the purine-cytosine permease of Saccharomyces cerevisiae.
Topics: Adenine; Alleles; Amino Acid Sequence; Amino Acid Substitution; Base Sequence; Biological Transport, Active; Carrier Proteins; Cytosine; DNA, Fungal; Escherichia coli; Hydrogen-Ion Concentration; Hypoxanthine; Kinetics; Membrane Transport Proteins; Mutagenesis, Site-Directed; Nucleobase Transport Proteins; Point Mutation; Proline; Protein Conformation; Recombinant Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 1999 |
Kelley-Seegmiller syndrome due to a unique variant of hypoxanthine-guanine phosphoribosyltransferase: reduced affinity for 5-phosphoribosyl-1-pyrophosphate manifested only at low, physiological substrate concentrations.
Topics: Acute Kidney Injury; Adenine; Cells, Cultured; Child, Preschool; Culture Media, Conditioned; DNA Mutational Analysis; Fibroblasts; Gout; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Jews; Lymphocytes; Male; Nucleic Acids; Nucleotides; Phosphoribosyl Pyrophosphate; Purines; Syndrome; Uric Acid | 2000 |
Substrate specificity of human methylpurine DNA N-glycosylase.
Topics: Adenine; Binding, Competitive; DNA; DNA Glycosylases; DNA Repair; Guanine; Guanosine; Humans; Hypoxanthine; Kinetics; N-Glycosyl Hydrolases; Oligonucleotides; Recombinant Proteins; Substrate Specificity | 2000 |
Influence of DNA structure on hypoxanthine and 1,N(6)-ethenoadenine removal by murine 3-methyladenine DNA glycosylase.
Topics: Adenine; Animals; Base Pairing; Base Sequence; DNA; DNA Glycosylases; Hypoxanthine; Mice; N-Glycosyl Hydrolases; Nucleic Acid Conformation | 2000 |
Adenosine and its receptor agonists regulate nitric oxide production and RAW 264.7 macrophages via both receptor binding and its downstream metabolites-inosine.
Topics: Adenine; Adenosine; Bacterial Toxins; Cell Line; Dose-Response Relationship, Drug; Dyneins; Enterotoxins; Enzyme Inhibitors; Escherichia coli; Escherichia coli Proteins; Humans; Hypoxanthine; Inosine; Lipopolysaccharides; Macrophages; Nitric Oxide; Nitric Oxide Synthase; Purinergic P1 Receptor Agonists | 2000 |
Adenoviruses encoding HPRT correct biochemical abnormalities of HPRT-deficient cells and allow their survival in negative selection medium.
Topics: Adenine; Adenoviridae; Animals; Carbon Radioisotopes; Cell Survival; Cells, Cultured; Culture Media; Cytomegalovirus; DNA, Complementary; Fibroblasts; Genes, Immediate-Early; Genetic Therapy; Genetic Vectors; Glycine; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Lesch-Nyhan Syndrome; Mice; Promoter Regions, Genetic; Ribonucleotides; Time Factors; Transcription, Genetic | 1999 |
Selective blockage of the 3'-->5' exonuclease activity of WRN protein by certain oxidative modifications and bulky lesions in DNA.
Topics: Adenine; Base Sequence; DNA; DNA Adducts; DNA Helicases; DNA Polymerase I; Exodeoxyribonucleases; Exonucleases; Guanine; Hypoxanthine; Mutation; Oxidation-Reduction; RecQ Helicases; Substrate Specificity; Uracil; Werner Syndrome Helicase | 2000 |
Evidence for increased dorsal hippocampal adenosine release and metabolism during pharmacologically induced seizures in rats.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Bicuculline; Convulsants; Disease Models, Animal; Electroencephalography; Enzyme Inhibitors; Excitatory Amino Acid Agonists; GABA Antagonists; Guanosine; Hippocampus; Hypoxanthine; Inosine; Kainic Acid; Male; Microdialysis; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Seizures; Xanthine | 2000 |
Purine-induced alterations of dopamine metabolism in rat pheochromocytoma PC12 cells.
Topics: Adenine; Adenosine; Animals; Disease Models, Animal; Dopamine; Guanine; Guanosine; Hypoxanthine; Neostriatum; Neural Pathways; Neurons; Parkinson Disease; PC12 Cells; Purines; Rats; Substantia Nigra; Uric Acid; Xanthine | 2000 |
Purine uptake and release in rat C6 glioma cells: nucleoside transport and purine metabolism under ATP-depleting conditions.
Topics: Adenine; Adenosine; Adenosine Triphosphate; AMP Deaminase; Animals; Carrier Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Equilibrative Nucleoside Transport Proteins; Equilibrative-Nucleoside Transporter 2; Formycins; Glioma; Hypoxanthine; Inosine; Iodoacetates; Nucleosides; Phosphodiesterase Inhibitors; Purines; Rats; Reverse Transcriptase Polymerase Chain Reaction; Sodium; Sodium Cyanide; Thioinosine; Tumor Cells, Cultured | 2000 |
Ischemic-like condition releases norepinephrine and purines from different sources in superfused rat spleen strips.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Hypoxanthine; Inosine; Ischemia; Male; Norepinephrine; Rats; Rats, Wistar; Spleen; Sympathectomy; Sympathetic Nervous System; Sympathomimetics; Tetrodotoxin; Tritium; Vasodilator Agents; Xanthine | 2000 |
Differential adsorption of nucleic acid bases: Relevance to the origin of life.
Topics: Adenine; Adsorption; Cytosine; Guanine; Hypoxanthine; Origin of Life; Purines; Pyrimidines; RNA; Surface Properties; Thymine; Uracil | 2001 |
Renal interstitial adenosine metabolism during ischemia in dogs.
Topics: Adenine; Adenosine; Animals; Antibiotics, Antineoplastic; Dogs; Extracellular Space; Hypoxanthine; Inosine; Ischemia; Kidney; Tubercidin | 2001 |
Binding of adenine and adenine-related compounds to the clay montmorillonite and the mineral hydroxylapatite.
Topics: Adenine; Adenosine; Aminoimidazole Carboxamide; Bentonite; Binding Sites; Durapatite; Evolution, Chemical; Evolution, Molecular; Hydrogen-Ion Concentration; Hypoxanthine; Nucleosides; Nucleotides; Origin of Life; Purines; Pyrimidines; RNA | 1995 |
Substitution F569S converts UapA, a specific uric acid-xanthine transporter, into a broad specificity transporter for purine-related solutes.
Topics: Adenine; Alleles; Amino Acid Substitution; Aspergillus nidulans; Binding, Competitive; Biological Transport; Fungal Proteins; Genes, Fungal; Hypoxanthine; Kinetics; Membrane Transport Proteins; Purines; Solubility; Structure-Activity Relationship; Substrate Specificity; Suppression, Genetic; Uracil; Urea; Uric Acid; Xanthine | 2001 |
Purine and pyrimidine salvage in whole rat brain. Utilization of ATP-derived ribose-1-phosphate and 5-phosphoribosyl-1-pyrophosphate generated in experiments with dialyzed cell-free extracts.
Topics: Adenine; Adenosine Triphosphate; Animals; Brain; Cell-Free System; Cytosine; Dose-Response Relationship, Drug; Hypoxanthine; Ischemia; Models, Chemical; Pentoses; Phosphoribosyl Pyrophosphate; Purines; Pyrimidines; Rats; Reperfusion Injury; Ribosemonophosphates; Time Factors | 2002 |
Adenoviruses encoding HPRT correct the biochemical abnormalities fully only in HPRT-deficient human cell lines: importance of species differences.
Topics: Adenine; Adenoviruses, Human; Animals; Cell Line; Cell Survival; Gene Transfer Techniques; Genetic Vectors; Guanosine Triphosphate; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Mice; Uric Acid; Uridine Diphosphate Glucose; Xanthine | 2000 |
The kinetics of hypoxanthine transport across the perfused choroid plexus of the sheep.
Topics: Adenine; Allopurinol; Animals; Binding, Competitive; Biological Transport; Carbon Radioisotopes; Choroid Plexus; Dose-Response Relationship, Drug; Hypoxanthine; In Vitro Techniques; Mannitol; Perfusion; Sheep; Sodium; Thioinosine; Thymine; Tritium; Uracil; Xanthine Oxidase | 2002 |
Primordial coding of amino acids by adsorbed purine bases.
Topics: Adenine; Adsorption; Amino Acids; Chromatography; Crystallization; Evolution, Chemical; Genetic Code; Graphite; Hypoxanthine; Microscopy, Scanning Tunneling; Purines; Templates, Genetic | 2002 |
Mitochondrial DNA repair of oxidative damage in mammalian cells.
Topics: Adenine; Aging; Animals; Cell Nucleus; DNA Damage; DNA Glycosylases; DNA Ligases; DNA Repair; DNA-Binding Proteins; DNA-Formamidopyrimidine Glycosylase; DNA, Mitochondrial; Guanosine; Humans; Hypoxanthine; Mice; Mitochondria, Heart; Mitochondria, Liver; N-Glycosyl Hydrolases; Oxidative Stress; Rats; Reactive Oxygen Species; X-ray Repair Cross Complementing Protein 1 | 2002 |
Mechanisms of apoptosis induced by purine nucleosides in astrocytes.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Apoptosis; Astrocytes; Carrier Proteins; Cells, Cultured; Central Nervous System; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Guanine; Guanosine; Hypoxanthine; Inosine; Male; Purine Nucleosides; Purinergic P1 Receptor Antagonists; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A3; Receptors, Purinergic P1; RNA, Messenger | 2002 |
Different substrate recognition motifs of human and trypanosome nucleobase transporters. Selective uptake of purine antimetabolites.
Topics: Adenine; Animals; Antimetabolites; Carrier Proteins; Erythrocytes; Guanine; Humans; Hydrogen Bonding; Hypoxanthine; Membrane Proteins; Nucleoside Transport Proteins; Protein Binding; Protein Conformation; Purines; Structure-Activity Relationship; Trypanosoma brucei brucei | 2002 |
Purine metabolism and release during cardioprotection with hyperkalemia and hypothermia.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Animals; Guinea Pigs; Heart; Hyperkalemia; Hypothermia; Hypoxanthine; Inosine; L-Lactate Dehydrogenase; Lactates; Myocardium; Purines; Reperfusion Injury; Temperature; Time Factors; Xanthine | 2002 |
[Separation and determination of purine bases and pyrimidine bases from nucleic acid hydrolysis by HPLC on BDS column].
Topics: Adenine; Chromatography, High Pressure Liquid; Cytosine; Guanine; Hypoxanthine; Nucleic Acids; Purines; Pyrimidines; Thymine; Uracil; Yeasts | 2000 |
A Leishmania major nucleobase transporter responsible for allopurinol uptake is a functional homolog of the Trypanosoma brucei H2 transporter.
Topics: Adenine; Allopurinol; Animals; Biological Transport; Hypoxanthine; Leishmania major; Nucleobase Transport Proteins; Structure-Activity Relationship; Tritium; Trypanosoma brucei brucei | 2003 |
Cytological studies on the antimetabolite action of 2, 6-diaminopurine in Vicia faba roots.
Topics: 2-Aminopurine; Adenine; Adenosine; Antimetabolites; Cell Division; Deoxyadenosines; DNA; Growth; Guanine; Hypoxanthine; Purines; Vicia faba | 1955 |
Breakdown of adenine and hypoxanthine nucleotides and nucleosides in human plasma.
Topics: Adenine; Blood; Humans; Hypoxanthine; Nucleosides; Nucleotides | 1956 |
[Fractionated precipitation of purine bases by silver oxide in a highly acid medium; application to the paper chromatographic determination of adenine, guanine and hypoxanthine in a hydrolysate].
Topics: Adenine; Chromatography; Guanine; Hypoxanthine; Oxides; Purines; Silver Compounds; Xanthines | 1956 |
Utilization of hypoxanthine, adenine and 4-amino-5-imidazole-carboxamide for uric acid synthesis in man.
Topics: Adenine; Amides; Humans; Hypoxanthine; Imidazoles; Male; Uric Acid; Xanthines | 1959 |
The high permeability of human red cells to adenine and hypoxanthine and their ribosides.
Topics: Adenine; Erythrocytes; Humans; Hypoxanthine; Nucleosides; Nucleotides; Permeability; Xanthines | 1960 |
Separation of adenine, hypoxanthine, and the 5'-(mono-,di-,and tri-)-phosphates of adenosine and inosine by one-dimensional paper chromatography.
Topics: Adenine; Adenine Nucleotides; Adenosine; Chromatography; Chromatography, Paper; Hypoxanthine; Inosine; Nucleosides; Nucleotides; Phosphates; Retinal Degeneration; Retinal Detachment | 1962 |
SOME INHIBITORY PROPERTIES OF 6-N-HYDROXYLAMINOPURINE: AN ANALOG OF ADENINE AND HYPOXANTHINE.
Topics: Adenine; Adenine Nucleotides; Animals; Antimetabolites; Carbon Isotopes; Glycine; Guanine Nucleotides; Hydroxylamines; Hypoxanthine; Hypoxanthines; Lymphoma; Mice; Neoplasms, Experimental; Nucleotidyltransferases; Pharmacology; Purines; Research; Sarcoma 180; Tissue Culture Techniques | 1964 |
NUTRITION OF "ADENINELESS" AUXOTROPHS OF YEASTS.
Topics: Adenine; Guanine; Guanosine; Hypoxanthine; Hypoxanthines; Inosine; Nucleosides; Nucleotides; Purines; Research; Ribonucleotides; Saccharomyces; Xanthines; Yeasts | 1964 |
PURINE METABOLISM BY UNICELLULAR ALGAE. II. ADENINE, HYPOXANTHINE, AND XANTHINE DEGRADATION BY CHORELLA PYRENOIDOSA.
Topics: Adenine; Allantoin; Biochemical Phenomena; Chromatography; Eukaryota; Hypoxanthine; Hypoxanthines; Metabolism; Research; Spectrophotometry; Uric Acid; Xanthine; Xanthines | 1964 |
STUDIES IN PURINE CHEMISTRY. 13. SYNTHESIS OF THE 5-AZA ANALOGS OF ADENINE AND HYPOXANTHINE.
Topics: Adenine; Antimetabolites; Chemical Phenomena; Chemistry; Hypoxanthine; Hypoxanthines; Organic Chemicals; Purines; Research | 1965 |
Cofactor determination and spectroscopic characterization of the selenium-dependent purine hydroxylase from Clostridium purinolyticum.
Topics: Adenine; Clostridium; Cyanides; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Flavin-Adenine Dinucleotide; Flavins; Hydrogen-Ion Concentration; Hydroxylation; Hypoxanthine; Iron; Isotopes; Kinetics; Molybdenum; NADH, NADPH Oxidoreductases; NADP; Purines; Selenium; Spectrophotometry; Xanthine Dehydrogenase | 2003 |
Mechanisms of arsenical and diamidine uptake and resistance in Trypanosoma brucei.
Topics: Adenine; Adenosine; Animals; Arsenicals; Benzamidines; Cell Death; Cell Division; Diminazene; Drug Resistance; Female; Gene Silencing; Hypoxanthine; Inhibitory Concentration 50; Inosine; Melarsoprol; Mice; Mutation; Nucleoside Transport Proteins; Pentamidine; Stilbamidines; Trypanosoma brucei brucei | 2003 |
Isolation of a Chinese hamster cell mutant with low intracellular phosphoribosylpyrophosphate concentration.
Topics: Adenine; Adenine Phosphoribosyltransferase; Animals; Cell Line; Cricetinae; Cricetulus; Guanine; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Mutation; Phosphoribosyl Pyrophosphate; Ribose-Phosphate Pyrophosphokinase; Tritium | 1982 |
The AzgA purine transporter of Aspergillus nidulans. Characterization of a protein belonging to a new phylogenetic cluster.
Topics: Adenine; Alleles; Amino Acid Sequence; Aspergillus nidulans; Biological Transport; Blotting, Northern; Carrier Proteins; Cell Membrane; Cloning, Molecular; DNA; Escherichia coli; Gene Deletion; Hypoxanthine; Membrane Transport Proteins; Models, Genetic; Molecular Sequence Data; Multigene Family; Mutagenesis; Mutation; Nitrogen; Phenotype; Phylogeny; Plasmids; Protein Structure, Tertiary; Quaternary Ammonium Compounds; Sequence Homology, Amino Acid; Time Factors; Transcription, Genetic; Ultraviolet Rays; Uric Acid | 2004 |
Simultaneous separation and determination of active components in Cordyceps sinensis and Cordyceps militarris by LC/ESI-MS.
Topics: Adenine; Adenosine; Cordyceps; Deoxyadenosines; Drugs, Chinese Herbal; Gas Chromatography-Mass Spectrometry; Hypoxanthine; Nucleosides; Principal Component Analysis; Spectrometry, Mass, Electrospray Ionization | 2003 |
The Bacillus subtilis counterpart of the mammalian 3-methyladenine DNA glycosylase has hypoxanthine and 1,N6-ethenoadenine as preferred substrates.
Topics: Adenine; Alkylation; Animals; Bacillus subtilis; Cloning, Molecular; Deamination; DNA Glycosylases; DNA Methylation; Escherichia coli; Hypoxanthine; Mammals; Molecular Sequence Data; Mutation; Open Reading Frames; Sequence Homology, Amino Acid; Substrate Specificity | 2004 |
[Analysis of the mutagenic activity examplified by interaction of DNA bases with nitrous acid].
Topics: Adenine; Chromatography, Thin Layer; Cytosine; DNA; Hypoxanthine; Mutagenicity Tests; Nitrous Acid; Spectrometry, Fluorescence; Uracil | 2004 |
The fidelity of replication of the three-base-pair set adenine/thymine, hypoxanthine/cytosine and 6-thiopurine/5-methyl-2-pyrimidinone with T7 DNA polymerase.
Topics: Adenine; Base Pairing; Cytosine; DNA Replication; DNA-Directed DNA Polymerase; Hypoxanthine; Kinetics; Mercaptopurine; Models, Genetic; Purines; Pyrimidinones; Research Design; Sensitivity and Specificity; Thymine | 2004 |
A new synthesis of the purines adenine, hypoxanthine, xanthine, and isoguanine.
Topics: Adenine; Guanine; Hypoxanthine; Purines; Xanthine; Xanthines | 1950 |
Effect of testosterone on purine nucleotide metabolism in rat liver.
Topics: Adenine; Androgens; Animals; Guanine; Hypoxanthine; Liver; Male; Models, Biological; Orchiectomy; Purine Nucleotides; Rats; Rats, Wistar; Testosterone | 2004 |
Targeting a novel Plasmodium falciparum purine recycling pathway with specific immucillins.
Topics: Adenine; Adenosine Deaminase; Amino Acid Sequence; Animals; Conserved Sequence; Escherichia coli; Humans; Hypoxanthine; Inosine; Methylthioinosine; Molecular Sequence Data; Plasmodium falciparum; Purine-Nucleoside Phosphorylase; Purines; Sequence Alignment; Sequence Homology, Amino Acid | 2005 |
Assay of adenosine deaminase isoforms by HPLC.
Topics: Adenine; Adenosine; Adenosine Deaminase; Benzyl Compounds; Chromatography, High Pressure Liquid; Hypoxanthine; Inosine; Isoenzymes | 2006 |
Characterization of novel Na+-dependent nucleobase transport systems at the blood-testis barrier.
Topics: Adenine; Animals; Biological Transport; Blood-Testis Barrier; Cytosine; Guanine; Hypoxanthine; Kinetics; Male; Meglumine; Nucleobase Transport Proteins; Nucleoside Transport Proteins; Purine Nucleosides; Pyrimidine Nucleosides; Rats; Rats, Inbred Strains; Sertoli Cells; Sodium; Thioinosine; Thymine; Uracil; Uridine | 2006 |
Magnesium, essential for base excision repair enzymes, inhibits substrate binding of N-methylpurine-DNA glycosylase.
Topics: Adenine; Animals; DNA Glycosylases; DNA Repair; Hypoxanthine; Magnesium; Mice; Protein Binding; Substrate Specificity | 2006 |
Regulation of purine nucleotide biosynthesis: in yeast and beyond.
Topics: Adenine; Bacillus subtilis; Escherichia coli; Guanine; Hypoxanthine; Lactococcus lactis; Models, Biological; Purine Nucleotides; Saccharomyces cerevisiae; Salmonella typhimurium; Signal Transduction; Transcriptional Activation | 2006 |
Evaluation of uridine metabolism in human and animal spermatozoa.
Topics: Adenine; Animals; Chromatography, High Pressure Liquid; Humans; Hypoxanthine; Image Processing, Computer-Assisted; Male; Nucleotides; Phosphorylation; Ribose; Semen; Sperm Motility; Spermatozoa; Uridine; Uridine Phosphorylase | 2006 |
Differential physiological and developmental expression of the UapA and AzgA purine transporters in Aspergillus nidulans.
Topics: Adenine; Aspergillus nidulans; Biological Transport; Carrier Proteins; Cell Membrane; Culture Media; Down-Regulation; Fungal Proteins; Guanine; Hyphae; Hypoxanthine; Immunoblotting; Membrane Transport Proteins; Purines; Quaternary Ammonium Compounds | 2007 |
Immobilized Escherichia coli BL21 as a catalyst for the synthesis of adenine and hypoxanthine nucleosides.
Topics: Adenine; Catalysis; Escherichia coli; Escherichia coli Proteins; Hypoxanthine; Nucleosides | 2004 |
A potential prebiotic route to adenine from hypoxanthine.
Topics: Adenine; Glycine; Guanine; Hypoxanthine; Molecular Structure; Urea; Xanthine | 2005 |
Qualitative and quantitative analyses of nucleosides and nucleobases in Ganoderma spp. by HPLC-DAD-MS.
Topics: Adenine; Chromatography, High Pressure Liquid; Fruiting Bodies, Fungal; Ganoderma; Guanine; Hypoxanthine; Mass Spectrometry; Molecular Structure; Nucleosides; Plant Extracts; Reference Standards; Reproducibility of Results; Species Specificity; Technology, Pharmaceutical; Thymine; Uracil | 2007 |
An unusual mode of DNA duplex association: Watson-Crick interaction of all-purine deoxyribonucleic acids.
Topics: Adenine; Base Pairing; Benzothiazoles; Circular Dichroism; Diamines; DNA; Electrophoresis, Polyacrylamide Gel; Guanine; Hypoxanthine; Oligodeoxyribonucleotides; Organic Chemicals; Purines; Quinolines; Ribonucleosides; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Thermodynamics | 2007 |
Purine nucleobase transport in the intraerythrocytic malaria parasite.
Topics: Adenine; Adenosine Triphosphate; Animals; Biological Transport; Cells, Cultured; Erythrocytes; Hypoxanthine; Malaria, Falciparum; Nucleobase Transport Proteins; Nucleobase, Nucleoside, Nucleotide, and Nucleic Acid Transport Proteins; Oocytes; Parasitology; Plasmodium falciparum; Protozoan Proteins; Xenopus laevis | 2008 |
Transport of [14C]hypoxanthine by sheep choroid plexus epithelium as a monolayer in primary culture: Na+-dependent and Na+-independent uptake by the apical membrane and rapid intracellular metabolic conversion to nucleotides.
Topics: Adenine; Animals; Carbon Radioisotopes; Cell Membrane; Cell Membrane Permeability; Cells, Cultured; Choroid Plexus; Epithelial Cells; Guanine; Hypoxanthine; Nucleotides; Protein Transport; Sheep; Sodium; Time Factors | 2008 |
Enhancement of glutathione production by altering adenosine metabolism of Escherichia coli in a coupled ATP regeneration system with Saccharomyces cerevisiae.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Bioreactors; Escherichia coli; Glucose; Glutathione; Glycolysis; Hypoxanthine; Industrial Microbiology; Saccharomyces cerevisiae | 2008 |
An ab initio study of substituent effects on the excited states of purine derivatives.
Topics: 2-Aminopurine; Adenine; Electrons; Gases; Guanine; Hypoxanthine; Isomerism; Purines; Quantum Theory; Xanthine | 2008 |
Thermus thermophilus strains active in purine nucleoside synthesis.
Topics: Adenine; Hypoxanthine; Kinetics; Pentosyltransferases; Purine Nucleosides; Pyrimidine Nucleosides; Thermus thermophilus | 2009 |
An acid-activated nucleobase transporter from Leishmania major.
Topics: Acids; Adenine; Allopurinol; Animals; Antimetabolites; Hydrogen-Ion Concentration; Hypoxanthine; Leishmania major; Membrane Transport Proteins; Nucleobase Transport Proteins; Oocytes; Patch-Clamp Techniques; Phagosomes; Tritium; Xenopus | 2009 |
Excised damaged base determines the turnover of human N-methylpurine-DNA glycosylase.
Topics: Adenine; Base Sequence; Binding Sites; DNA; DNA Damage; DNA Glycosylases; Enzyme Stability; Glycosides; Humans; Hypoxanthine; Kinetics; Molecular Sequence Data; Surface Plasmon Resonance | 2009 |
An enzyme-coupled continuous spectrophotometric assay for magnesium protoporphyrin IX methyltransferases.
Topics: Adenine; Aminohydrolases; Biological Assay; Cyanobacteria; Escherichia coli; Hypoxanthine; Kinetics; Methyltransferases; Molecular Structure; Protoporphyrins; Recombinant Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Spectrophotometry; Substrate Specificity; Synechocystis; Transformation, Bacterial | 2009 |
Adenine metabolism in Plasmodium falciparum.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine Monophosphate; Adenylosuccinate Synthase; Enzyme Inhibitors; Glycine; Hypoxanthine; Inhibitory Concentration 50; Plasmodium falciparum | 2010 |
Guanine, adenine, and hypoxanthine production in UV-irradiated formamide solutions: relaxation of the requirements for prebiotic purine nucleobase formation.
Topics: Adenine; Formamides; Guanine; Hot Temperature; Hypoxanthine; Prebiotics; Purine Nucleosides; Ultraviolet Rays | 2010 |
Promiscuous DNA alkyladenine glycosylase dramatically favors a bound lesion over undamaged adenine.
Topics: Adenine; Binding Sites; DNA; DNA Glycosylases; DNA Repair; Humans; Hypoxanthine; Monte Carlo Method; Protein Binding; Protein Structure, Tertiary; Thermodynamics | 2010 |
Diversity of the early step of the futalosine pathway.
Topics: Adenine; Bacteria; Chromatography, High Pressure Liquid; Helicobacter pylori; Hydrolases; Hypoxanthine; Nucleosides; Thermus thermophilus; Vitamin K 2 | 2011 |
Determination of the nucleosides and nucleobases in Tuber samples by dispersive solid-phase extraction combined with liquid chromatography-mass spectrometry.
Topics: Adenine; Adenosine; Agaricales; Chromatography, High Pressure Liquid; Chromatography, Liquid; Fermentation; Guanine; Guanosine; Hypoxanthine; Inosine; Mass Spectrometry; Nucleosides; Plant Extracts; Plant Tubers; Solid Phase Extraction; Tandem Mass Spectrometry; Uridine | 2011 |
The PurR regulon in Escherichia coli K-12 MG1655.
Topics: Adenine; Binding Sites; Chromatin Immunoprecipitation; Escherichia coli K12; Escherichia coli Proteins; Gene Deletion; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Genome, Bacterial; Hypoxanthine; Metabolic Networks and Pathways; Regulon; Repressor Proteins | 2011 |
[Determination of nucleosides in Rhizoma Pinelliae by high performance liquid chromatography].
Topics: Adenine; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Hypoxanthine; Nucleosides; Pinellia; Plant Tubers; Thymine | 2011 |
Simultaneous determination of five nucleosides and nucleobases of Rehmannia glutinosa Libosch. by high performance liquid chromatography.
Topics: Adenine; Adenosine; Chromatography, High Pressure Liquid; Guanosine; Hypoxanthine; Nucleosides; Plants, Medicinal; Rehmannia; Uridine | 2011 |
Borrelia burgdorferi harbors a transport system essential for purine salvage and mammalian infection.
Topics: Adenine; Animals; Borrelia burgdorferi; Disease Models, Animal; Female; Guanine; Hypoxanthine; Lyme Disease; Membrane Transport Proteins; Mice; Mice, Inbred C3H; Plasmids; Virulence Factors | 2012 |
Modeling, substrate docking, and mutational analysis identify residues essential for the function and specificity of a eukaryotic purine-cytosine NCS1 transporter.
Topics: Adenine; Amino Acid Motifs; Amino Acid Substitution; Aspergillus nidulans; Conserved Sequence; Cytosine; Fungal Proteins; Guanine; Hydrogen Bonding; Hypoxanthine; Kinetics; Molecular Docking Simulation; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Phenotype; Protein Binding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Structural Homology, Protein; Substrate Specificity; Symporters | 2012 |
Effects of hypoxanthine substitution in peptide nucleic acids targeting KRAS2 oncogenic mRNA molecules: theory and experiment.
Topics: Adenine; Algorithms; Base Pairing; Circular Dichroism; Guanine; Humans; Hypoxanthine; Models, Molecular; Molecular Dynamics Simulation; Nucleic Acid Denaturation; Peptide Nucleic Acids; Point Mutation; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; RNA, Messenger; Transition Temperature; Uracil | 2013 |
Low-potential amperometric determination of purine derivatives through surface oxide regeneration method.
Topics: Adenine; Copper; Electrochemical Techniques; Guanine; Hypoxanthine; Limit of Detection; Oxidation-Reduction; Purines; Uric Acid; Xanthine | 2013 |
Arxula adeninivorans recombinant urate oxidase and its application in the production of food with low uric acid content.
Topics: Adenine; DNA, Fungal; Enzyme Stability; Food Handling; Gene Expression Profiling; Hydrogen-Ion Concentration; Hypoxanthine; Molecular Sequence Data; Recombinant Proteins; Saccharomycetales; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Substrate Specificity; Temperature; Urate Oxidase; Uric Acid | 2013 |
Specificities and pH profiles of adenine and hypoxanthine-guanine-xanthine phosphoribosyltransferases (nucleotide synthases) of the thermoacidophile archaeon Sulfolobus solfataricus.
Topics: Adenine; Amino Acid Sequence; Archaeal Proteins; Base Sequence; Guanine; Hydrogen-Ion Concentration; Hypoxanthine; Molecular Sequence Data; Pentosyltransferases; Substrate Specificity; Sulfolobus solfataricus; Xanthine | 2014 |
Free radical routes for prebiotic formation of DNA nucleobases from formamide.
Topics: Adenine; Evolution, Chemical; Formamides; Free Radicals; Guanine; Hypoxanthine; Molecular Structure; Purines | 2013 |
[Determination of four kinds of purines in deer fetus soft capsule by HPLC].
Topics: Adenine; Animals; Capsules; Chromatography, High Pressure Liquid; Deer; Fetus; Guanine; Hypoxanthine; Materia Medica; Purines; Quality Control; Reproducibility of Results; Xanthine | 2014 |
Low-level expression of purine bases in BALB/3T3 cells monitored by ultrasensitive graphene-based glass carbon electrode.
Topics: Adenine; Animals; BALB 3T3 Cells; Biosensing Techniques; Carbon; Electrochemical Techniques; Electrodes; Glass; Graphite; Humans; Hypoxanthine; MCF-7 Cells; Mice; Oxidation-Reduction | 2014 |
Electron ionization of the nucleobases adenine and hypoxanthine near the threshold: a combined experimental and theoretical study.
Topics: Adenine; DNA; Electrons; Hypoxanthine; Mass Spectrometry; Models, Molecular; Molecular Conformation | 2014 |
Synthesis, conformational studies, and biological properties of phosphonomethoxyethyl derivatives of nucleobases with a locked conformation via a pyrrolidine ring.
Topics: Adenine; Animals; Antimalarials; Chemistry, Pharmaceutical; Drug Design; Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hypoxanthine; Kinetics; Magnetic Resonance Spectroscopy; Organophosphonates; Oxygen; Pentosyltransferases; Plasmodium falciparum; Protein Conformation; Pyrrolidines; Structure-Activity Relationship | 2015 |
Functional identification of SLC43A3 as an equilibrative nucleobase transporter involved in purine salvage in mammals.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine; Amino Acid Transport Systems; Animals; Biological Transport; Dogs; Equilibrative Nucleoside Transporter 1; HEK293 Cells; HeLa Cells; Hepatocytes; Humans; Hypoxanthine; Liver; Lung; Madin Darby Canine Kidney Cells; Mice; Protein Isoforms; Purines; RNA, Small Interfering; Thymidine; Uridine | 2015 |
[Determination of Nucleosides and Nucleobases in Natural, Cultured and Tissue Culture Anoectochilus roxburghii Using LC-MS].
Topics: Adenine; Adenosine; Chromatography, Liquid; Drugs, Chinese Herbal; Guanosine; Hypoxanthine; Mass Spectrometry; Nucleosides; Nucleotides; Orchidaceae; Uracil; Uridine | 2015 |
Butyrate influences intracellular levels of adenine and adenine derivatives in the fungus Penicillium restrictum.
Topics: Adenine; Adenosine; Anti-Infective Agents; Biomass; Butyrates; Chromatography, High Pressure Liquid; Cyclic AMP; Cytoplasm; Hypoxanthine; Microbial Sensitivity Tests; Penicillium; Spores, Fungal; Staphylococcus aureus | 2017 |
Prebiotic stereoselective synthesis of purine and noncanonical pyrimidine nucleotide from nucleobases and phosphorylated carbohydrates.
Topics: Adenine; Carbohydrates; Chromatography, High Pressure Liquid; Cytidine; Evolution, Chemical; Hypoxanthine; Magnetic Resonance Spectroscopy; Organophosphates; Origin of Life; Phosphorylation; Purine Nucleotides; Pyrimidine Nucleotides | 2017 |
Trypanosoma brucei bloodstream forms express highly specific and separate transporters for adenine and hypoxanthine; evidence for a new protozoan purine transporter family?
Topics: Adenine; Culture Media; Gene Deletion; Hypoxanthine; Kinetics; Nucleobase Transport Proteins; Substrate Specificity; Trypanosoma brucei brucei | 2018 |
Base-Pairing Properties of Double-Headed Nucleotides.
Topics: 2-Aminopurine; Adenine; Base Pair Mismatch; Base Pairing; Cytosine; DNA; Guanine; Hypoxanthine; Models, Molecular; Nucleic Acid Conformation; Nucleotides; Thymine | 2019 |
Nucleobase synthesis in interstellar ices.
Topics: Adenine; Ammonia; Carbon Monoxide; Cytosine; Evolution, Chemical; Extraterrestrial Environment; Hypoxanthine; Ice; Methanol; Molecular Structure; Photochemical Processes; Thymine; Ultraviolet Rays; Uracil; Water; Xanthine | 2019 |
Specificity profile of NAT/NCS2 purine transporters in Sinorhizobium (Ensifer) meliloti.
Topics: Adenine; Biological Transport, Active; Escherichia coli K12; Guanine; Hypoxanthine; Membrane Transport Proteins; Plant Root Nodulation; Rhizosphere; Root Nodules, Plant; Sinorhizobium meliloti; Symporters; Uric Acid; Xanthine | 2020 |
Chemical evolution: from formamide to nucleobases and amino acids without the presence of catalyst.
Topics: Adenine; Amino Acids; Catalysis; Formamides; Hypoxanthine | 2021 |
Frequency and hydrogen bonding of nucleobase homopairs in small molecule crystals.
Topics: Adenine; Base Pairing; Crystallography, X-Ray; Cytosine; Databases, Protein; Guanine; Hydrogen Bonding; Hypoxanthine; Molecular Structure; Protein Conformation; Proteins; Small Molecule Libraries; Thymine; Uracil | 2020 |
Biochemical characterization and mutational studies of a novel 3-methlyadenine DNA glycosylase II from the hyperthermophilic Thermococcus gammatolerans.
Topics: Adenine; Amino Acid Sequence; Bacterial Proteins; DNA Damage; DNA Glycosylases; DNA Repair; DNA, Bacterial; Hot Temperature; Hydrogen-Ion Concentration; Hypoxanthine; Kinetics; Mutation; Sequence Alignment; Substrate Specificity; Thermococcus | 2021 |
SLC23A3 is a renal hypoxanthine transporter.
Topics: Adenine; Animals; Biological Transport; Humans; Hypoxanthine; Kidney; Membrane Transport Proteins; Rats; Sodium; Xanthines | 2022 |
Intermediate products of purine metabolism in an experimental model of pancreatic necrosis.
Topics: Adenine; Animals; Guanine; Hypoxanthine; Models, Theoretical; Pancreatitis, Acute Necrotizing; Purines; Rabbits; Uric Acid; Xanthine | 2022 |