adenine has been researched along with hydroxyurea in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (52.94) | 18.7374 |
| 1990's | 8 (23.53) | 18.2507 |
| 2000's | 6 (17.65) | 29.6817 |
| 2010's | 2 (5.88) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fox, IH; Halsey, DL; Kaminska, J; Wortmann, RL | 1 |
| Kelley, WN; Mitchell, BS; Wilson, JM | 1 |
| Pardee, AB; Shilo, B; Simchen, G | 1 |
| Ikenaga, M; Kakunaga, T | 1 |
| Fraser, RS; Moreno, F | 1 |
| McClarty, G; Tipples, G | 1 |
| Howell, ML; Mathews, CK; Slabaugh, MB; Wang, Y | 1 |
| Carter, GL; Cory, JG | 1 |
| Grunow, R; Jahn, S; Kiessig, ST; Schäfer, H; Volk, HD; von Baehr, R | 1 |
| Burroughs, MA; Derge, JG; Hampar, B; Martos, LM; Tagamets, MA | 1 |
| Odmark, G | 1 |
| Cleaver, JE | 1 |
| Fangman, WL; Hill, WE | 1 |
| Kumar, HD; Singh, MK | 1 |
| Degnen, ST; Newton, A | 1 |
| Brockman, RW; Laster, WR; Schabel, FM; Shaddix, S | 1 |
| Granoff, A; Kucera, LS | 1 |
| Sung, SC | 1 |
| Bacon, PE; Carter, GL; Cory, JG; Sato, A | 2 |
| Kozubek, S; Mlejnek, P | 1 |
| Elson, P; Hsieh, P; Oken, MM; Trump, DL; Witte, RS | 1 |
| Merigan, TC; Palmer, S; Shafer, RW | 1 |
| Anton, KE; Cherrington, JM; Lamy, PD; Margot, NA; Miller, MD; Mulato, AS; Quan, Y; Salomon, H; Wainberg, MA | 1 |
| Crabbs, C; Greenhouse, J; Lewis, MG; Lisziewicz, J; Lori, F; Silvera, P; Tinelli, C; Varga, G; Wagner, W; Xu, J; Yalley-Ogunro, J; Zinn, DE | 1 |
| Fakuda, D | 1 |
| Carr, A; Chuah, J; Cooper, DA; Doong, N; French, M; Hoy, J; Hudson, J; Law, M; Mallal, S; Smith, D | 1 |
| Barditch-Crovo, P; Coakley, DF; Collier, A; Deeks, SG; McGowan, I; Miller, M; Smith, A | 1 |
| Bendele, RA; Richardson, FC | 1 |
| Kast, RE | 1 |
| Blank, A; Bobola, MS; D Kolstoe, D; Gold, B; Loeb, LA; Meade, EH; Rabinovitch, PS; Silber, JR; Varadarajan, S | 1 |
| Bernstein, KA; Godin, SK; Herken, BW; Lee, AG; Mihalevic, MJ; Resnick, MA; Sobol, RW; Westmoreland, JW; Yu, Z; Zhang, Z | 1 |
4 trial(s) available for adenine and hydroxyurea
| Article | Year |
|---|---|
A phase II trial of amonafide, caracemide, and homoharringtonine in the treatment of patients with advanced renal cell cancer.
Topics: Adenine; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Female; Harringtonines; Homoharringtonine; Humans; Hydroxyurea; Imides; Isoquinolines; Kidney Neoplasms; Male; Middle Aged; Naphthalimides; Organophosphonates; Survival Rate; Treatment Outcome | 1996 |
PMPA trials recruiting.
Topics: Adenine; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; HIV Infections; Humans; Hydroxyurea; Organophosphonates; Organophosphorus Compounds; Tenofovir; Viral Load | 1998 |
HIV protease inhibitor substitution in patients with lipodystrophy: a randomized, controlled, open-label, multicentre study.
Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Body Composition; Carnitine; Dideoxynucleosides; Drug Administration Schedule; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Hydroxyurea; Insulin Resistance; Lipodystrophy; Male; Middle Aged; Nevirapine; Organophosphonates; Quality of Life; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome | 2001 |
Hydroxyurea does not enhance the anti-HIV activity of low-dose tenofovir disoproxil fumarate.
Topics: Adenine; Adult; Anti-HIV Agents; Cohort Studies; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Hydroxyurea; Male; Organophosphonates; Organophosphorus Compounds; Tenofovir | 2001 |
30 other study(ies) available for adenine and hydroxyurea
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Deoxyadenosine inhibits DNA synthesis in cultured human fibroblasts.
Topics: Adenine; Adenosine Deaminase Inhibitors; Cells, Cultured; Deoxyadenine Nucleotides; Deoxyadenosines; DNA; Fibroblasts; Humans; Hydroxyurea; Lymphocyte Activation; RNA | 1979 |
Molecular mechanism(s) of deoxyribonucleoside toxicity in T-lymphoblasts.
Topics: Adenine; Deoxyadenosines; Deoxyguanosine; Deoxyribonucleosides; DNA; Humans; Hydroxyurea; Kinetics; T-Lymphocytes | 1979 |
Regulation of cell-cycle initiation in yeast by nutrients and protein synthesis.
Topics: Adenine; Cell Cycle; Cell Division; Cycloheximide; Fungal Proteins; Histidine; Hydroxyurea; Lysine; Methionine; Saccharomyces cerevisiae | 1978 |
Excision of 4-nitroquinoline 1-oxide damage and transformed in mouse cells.
Topics: 4-Nitroquinoline-1-oxide; Adenine; Cell Transformation, Neoplastic; Cells, Cultured; DNA Repair; DNA, Neoplasm; Guanine; Hydroxyurea; Nitroquinolines; Thymidine; Xeroderma Pigmentosum | 1977 |
Rates of synthesis of polyadenylated messenger RNA and ribosomal RNA during the cell cycle of Schizosaccharomyces pombe. With an appendix: calculation of the pattern of protein accumulation from observed changes in the rate of messenger RNA synthesis.
Topics: Adenine; Ascomycota; Cell Division; DNA; Fungal Proteins; Hydroxyurea; Kinetics; Mathematics; Poly A; RNA, Messenger; RNA, Ribosomal; Schizosaccharomyces | 1976 |
Isolation and initial characterization of a series of Chlamydia trachomatis isolates selected for hydroxyurea resistance by a stepwise procedure.
Topics: Adenine; Animals; Chlamydia trachomatis; Cytidine Diphosphate; DNA, Bacterial; Drug Resistance, Microbial; Guanazole; Hydroxyurea; L Cells; Mutation; Ribonucleotide Reductases; Selection, Genetic | 1991 |
Deoxyadenosine reverses hydroxyurea inhibition of vaccinia virus growth.
Topics: Adenine; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Antiviral Agents; Cells, Cultured; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Hydroxyurea; Ribonucleotide Reductases; Thymidine; Vaccinia virus; Viral Plaque Assay; Virus Replication | 1991 |
Cross-resistance patterns in hydroxyurea-resistant leukemia L1210 cells.
Topics: Adenine; Animals; Cell Line; Drug Resistance; Electron Spin Resonance Spectroscopy; Guanidines; Hydroxyurea; Isoquinolines; Leukemia L1210; Pyrazoles; Ribonucleotide Reductases | 1988 |
Influence of hydroxyurea on lectin-induced early and late events in peripheral blood lymphocyte cultures.
Topics: Adenine; Animals; B-Lymphocytes; Cells, Cultured; Fluorescence; Humans; Hydroxyurea; Immunoglobulins; Lectins; Lymphocyte Activation; Lymphocytes; Mitogens; Thymidine; Uridine | 1987 |
Sequence of spontaneous Epstein-Barr virus activation and selective DNA synthesis in activated cells in the presence of hydroxyurea.
Topics: Adenine; Antigens, Viral; Autoradiography; Bromodeoxyuridine; Carbon Isotopes; Carcinoma; Cell Line; Cells, Cultured; Centrifugation, Density Gradient; Cytarabine; DNA, Viral; Fluorescent Antibody Technique; Herpesviridae; Herpesvirus 4, Human; Humans; Hydroxyurea; Nasopharyngeal Neoplasms; Thymidine; Thymidine Kinase; Tritium; Virus Replication | 1972 |
True or apparent inhibition of nucleic acid synthesis by the chromosome-breaking purine derivatives adenine and 8-ethoxycaffeine.
Topics: Adenine; Caffeine; Deoxyadenosines; DNA; Hydroxyurea; Phosphates; Phosphorus Isotopes; Plants; RNA; Thymidine; Tritium | 1972 |
DNA repair with purines and pyrimidines in radiation- and carcinogen-damaged normal and xeroderma pigmentosum human cells.
Topics: Adenine; Carcinogens; Carmustine; Cells, Cultured; Deoxyadenosines; DNA; DNA Repair; DNA, Neoplasm; Guanidines; Guanine; HeLa Cells; Humans; Hydroxyurea; Hypoxanthines; Nitroso Compounds; Quinolines; Radiation Effects; Skin; Ultraviolet Rays; Xeroderma Pigmentosum | 1973 |
Single-strand breaks in deoxyribonucleic acid and viability loss during deoxyribonucleic acid synthesis inhibition in Escherichia coli.
Topics: Adenine; Carbon Radioisotopes; Cell Survival; Chromosomes, Bacterial; DNA, Bacterial; DNA, Single-Stranded; Escherichia coli; Hydroxyurea; Molecular Weight; Mutation; Nalidixic Acid; Nucleic Acid Denaturation; Temperature; Thymidine; Tritium | 1973 |
Action of hydroxyurea on Anabaena variabilis. II. Effects of pre- and post-treatment with chloramphenicol and base analogues.
Topics: Adenine; Amines; Azaguanine; Chloramphenicol; Cyanobacteria; Depression, Chemical; DNA; Drug Antagonism; Hydroxyurea; Protein Biosynthesis; Uracil | 1969 |
Dependence of cell division on the completion of chromosome replication in Caulobacter.
Topics: Adenine; Bacteria; Cell Division; Chemical Precipitation; Chromosomes, Bacterial; DNA Replication; DNA, Bacterial; Filtration; Hydroxyurea; Mitomycins; RNA, Bacterial; Trichloroacetic Acid; Tritium | 1972 |
Inhibition of ribonucleotide reductase, DNA synthesis, and L1210 leukemia by guanazole.
Topics: Adenine; Animals; Azaguanine; Carbon Isotopes; Carcinoma, Squamous Cell; Culture Techniques; DNA, Neoplasm; Female; Formates; Hydroxyurea; Hypoxanthines; Leucine; Leukemia L1210; Male; Mice; Neoplasm Proteins; Oxidoreductases; RNA, Neoplasm; Thymidine; Tritium; Uridine | 1970 |
Viruses and renal carcinoma of Rana pipiens. VI. Interrelationships of macromolecular synthesis and infectious virus production in frog virus 3-infected BHK 21/13 cells.
Topics: Adenine; Animals; Anura; Carbon Isotopes; Culture Techniques; Cycloheximide; Cytarabine; Dactinomycin; DNA; DNA, Viral; Herpesviridae; Hydroxyurea; Idoxuridine; Inclusion Bodies, Viral; Kidney Neoplasms; Leucine; Neoplasms, Experimental; Oncogenic Viruses; Protein Biosynthesis; RNA; RNA, Viral; Thymidine; Tritium; Uridine; Viral Proteins; Virus Replication | 1968 |
DNA synthesis in the developing rat brain.
Topics: Adenine; Aging; Animals; Animals, Newborn; Brain; Brain Chemistry; Carbon Isotopes; Cell-Free System; Cerebellum; Cerebral Cortex; Dactinomycin; Depression, Chemical; DNA; Hydroxyurea; Hypothalamus; Limbic System; Medulla Oblongata; Organ Size; Pons; Rats; RNA; Thymidine | 1969 |
Effects of biochemical modulation of drug combinations directed at the ribonucleotide reductase site on leukemia L1210 cell growth in culture.
Topics: Adenine; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cells, Cultured; Deferoxamine; Deoxyadenosines; Drug Synergism; Hydroxyurea; Leukemia L1210; Pyrazoles; Ribonucleotide Reductases | 1983 |
Effects of combinations of drugs having different modes of action at the ribonucleotide reductase site on growth of L1210 cells in culture.
Topics: Adenine; Animals; Antineoplastic Agents; Deferoxamine; Deoxyadenosines; Hydroxyurea; Kinetics; Leukemia L1210; Mice; Pyrazoles; Ribonucleotide Reductases | 1982 |
Protective effect of adenine on DNA synthesis in irradiated Ehrlich ascites tumor cells.
Topics: Adenine; Animals; Carcinoma, Ehrlich Tumor; DNA Replication; DNA, Neoplasm; Gamma Rays; Hydroxyurea; Kinetics; Mice; Radiation Protection; Tumor Cells, Cultured | 1997 |
Hydroxyurea enhances the activities of didanosine, 9-[2-(phosphonylmethoxy)ethyl]adenine, and 9-[2-(phosphonylmethoxy)propyl]adenine against drug-susceptible and drug-resistant human immunodeficiency virus isolates.
Topics: Adenine; Anti-HIV Agents; Antineoplastic Agents; Didanosine; DNA, Viral; Drug Resistance, Microbial; HIV Reverse Transcriptase; HIV-1; Humans; Hydroxyurea; Inhibitory Concentration 50; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Tenofovir; Thymidine | 1999 |
In vitro selection and characterization of HIV-1 with reduced susceptibility to PMPA.
Topics: Adenine; Anti-HIV Agents; Drug Resistance; HIV Reverse Transcriptase; HIV-1; Hydroxyurea; Mutation; Organophosphonates; Organophosphorus Compounds; Tenofovir | 1999 |
Control of SIV rebound through structured treatment interruptions during early infection.
Topics: Adenine; Animals; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Didanosine; Drug Administration Schedule; Hydroxyurea; Lymphocyte Activation; Macaca mulatta; Organophosphonates; Organophosphorus Compounds; Random Allocation; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Tenofovir; Viral Load; Viremia; Virus Replication | 2000 |
What's new, what's next?
Topics: Adenine; Anti-HIV Agents; Antiviral Agents; Carbamates; Decision Making; Dideoxynucleosides; Drug Resistance, Microbial; Drug Therapy, Combination; Furans; HIV Infections; HIV Protease Inhibitors; Humans; Hydroxyurea; Patient Compliance; Saquinavir; Sulfonamides | 1998 |
Adefovir nephrotoxicity and mitochondrial DNA depletion.
Topics: Adenine; Antiviral Agents; Clinical Trials, Phase III as Topic; Cyclooxygenase Inhibitors; DNA, Mitochondrial; Drug Therapy, Combination; HIV Infections; Humans; Hydroxyurea; Kidney Tubules; Mitochondria; Organophosphonates; Renal Insufficiency; Stavudine | 2002 |
Tenofovir, COX inhibitors and zileuton during cancer immunotherapies: up-regulated TNF-alpha increases antigen driven lymphocyte proliferation.
Topics: Adenine; Adenylyl Cyclases; Anti-HIV Agents; Cell Division; Cyclooxygenase Inhibitors; Humans; Hydroxyurea; Immunotherapy; Lipoxygenase Inhibitors; Lymphocytes; Neoplasms; Organophosphonates; Organophosphorus Compounds; Tenofovir; Tumor Necrosis Factor-alpha; Up-Regulation | 2003 |
The Werner syndrome protein confers resistance to the DNA lesions N3-methyladenine and O6-methylguanine: implications for WRN function.
Topics: 4-Nitroquinoline-1-oxide; Adenine; Alkylating Agents; Antineoplastic Agents; Apoptosis; Camptothecin; Carcinogens; Cells, Cultured; DNA Damage; DNA Helicases; DNA Replication; Drug Resistance; Exodeoxyribonucleases; Fibroblasts; Glioma; Guanine; Humans; Hydroxyurea; Netropsin; O(6)-Methylguanine-DNA Methyltransferase; Oligonucleotides, Antisense; RecQ Helicases; Werner Syndrome; Werner Syndrome Helicase | 2004 |
The Shu complex promotes error-free tolerance of alkylation-induced base excision repair products.
Topics: Adenine; Alkylation; Camptothecin; Cisplatin; DNA Damage; DNA Polymerase beta; DNA Repair; DNA, Fungal; Epistasis, Genetic; Etoposide; Genes, Fungal; Genetic Loci; Homologous Recombination; Humans; Hydrogen Peroxide; Hydroxyurea; Methyl Methanesulfonate; Models, Biological; Mutation; Mutation Rate; Protein Binding; Radiation, Ionizing; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Ultraviolet Rays | 2016 |