adenine and hydroxyl radical

adenine has been researched along with hydroxyl radical in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19902 (5.56)18.7374
1990's18 (50.00)18.2507
2000's6 (16.67)29.6817
2010's9 (25.00)24.3611
2020's1 (2.78)2.80

Authors

AuthorsStudies
Bailly, C; Bailly, F; Hénichart, JP; Waring, MJ1
Ding, ZM; Hurley, LH1
Haimanot, R; Malins, DC1
Churchill, ME; Suzuki, M1
Burkhoff, AM; Tullius, TD1
Aruoma, OI; Chimel, K; Cross, CE; Halliwell, B; Jenner, A; Spencer, JP; Wu, R1
Fuciarelli, AF; Miller, DL; Sisk, EC; Thomas, RM1
Carpenter, ML; Cassidy, SA; Fox, KR1
Ide, H; Kimura, Y; Yamaoka, T1
Price, MA; Tullius, TD1
Astier, A; Charloux, C; Loisance, D; Paul, M1
Carmical, JR; Dizdaroglu, M; Lloyd, RS; Zastawny, TH1
Khatchikian, G; Xia, Y; Zweier, JL1
Filutowicz, M; Levchenko, I1
Harshey, RM; Hurley, LH; Sun, D1
Ahmad, J; Ali, R; Ashok, BT1
Zastawny, TH1
Buc, H; Lavigne, M1
Dias, RM; Telo, JP; Vieira, AJ1
Fox, KR; Gong, B; Yan, Y1
Malins, DC; Ostrander, GK; Polissar, NL; Vinson, MA1
Brenowitz, M; Jamison, E; Pastor, N; Weinstein, H1
Barker, EA; Johnson, PM; Malins, DC; Polissar, NL; Vinson, MA; Wheeler, TM1
Kim, M; Minamoto, S; Nakagawa, T; Sano, M; Takeuchi, S; Yokozawa, T1
Astot, C; Dolezal, K; Moritz, T; Nordström, A; Sandberg, G; Tarkowska, D; Tarkowski, P1
Czyznikowska, Z1
Cheng, Q; Compaan, KR; Gu, J; Schaefer, HF1
Cagnin, M; Castino, R; Fiorentino, I; Giovia, A; Isidoro, C1
Chen, S; Fan, S; Ikejima, T; Li, L; Onodera, S; Qi, M; Tashiro, S; Yu, Y1
Milhøj, BO; Sauer, SP3
Adhikary, A; Banyasz, A; Improta, R; Ketola, TM; Markovitsi, D; Martinez-Fernandez, L; Muñoz-Losa, A; Rishi, S; Sevilla, MD1
Francés-Monerris, A; Merchán, M; Roca-Sanjuán, D1
Egan, RW; Misra, SK; Persoff, JJ; Sharp, JS; Weinberger, SR1
Leupold, MS; Lutze, HV; Merkus, VI; Rockel, SP; Schmidt, TC1

Reviews

1 review(s) available for adenine and hydroxyl radical

ArticleYear
[DNA oxidative damages--free radical modification of bases and sugar moieties].
    Postepy biochemii, 1997, Volume: 43, Issue:4

    Topics: Adenine; Anaerobiosis; Carbohydrate Metabolism; Cytosine; DNA; Free Radicals; Guanine; Hydroxyl Radical; Mutagenesis; Oxidation-Reduction; Purines; Pyrimidines

1997

Other Studies

35 other study(ies) available for adenine and hydroxyl radical

ArticleYear
Selective binding to AT sequences in DNA by an acridine-linked peptide containing the SPKK motif.
    Biochemical and biophysical research communications, 1992, Apr-30, Volume: 184, Issue:2

    Topics: Acridines; Adenine; Amino Acid Sequence; Base Sequence; Binding Sites; Deoxyribonuclease I; DNA; Edetic Acid; Ferric Compounds; Free Radicals; Hydroxides; Hydroxyl Radical; Iron Chelating Agents; Molecular Sequence Data; Nucleic Acid Conformation; Oligopeptides; Osmium Tetroxide; Thymine

1992
DNA interstrand cross-linking, DNA sequence specificity, and induced conformational changes produced by a dimeric analog of (+)-CC-1065.
    Anti-cancer drug design, 1991, Volume: 6, Issue:5

    Topics: Adenine; Antibiotics, Antineoplastic; Base Sequence; Copper; Cross-Linking Reagents; DNA; DNA Damage; DNA Fingerprinting; Duocarmycins; Electrophoresis; Hydroxides; Hydroxyl Radical; Indoles; Leucomycins; Molecular Sequence Data; Nucleic Acid Conformation; Oligonucleotides; Phenanthrolines; Structure-Activity Relationship; Urea

1991
4,6-Diamino-5-formamidopyrimidine, 8-hydroxyguanine and 8-hydroxyadenine in DNA from neoplastic liver of English sole exposed to carcinogens.
    Biochemical and biophysical research communications, 1990, Dec-14, Volume: 173, Issue:2

    Topics: Adenine; Animals; Carcinogens; DNA, Neoplasm; Flatfishes; Free Radicals; Hydroxides; Hydroxyl Radical; Liver Neoplasms; Pyrimidines

1990
'SPKK' motifs prefer to bind to DNA at A/T-rich sites.
    The EMBO journal, 1989, Dec-20, Volume: 8, Issue:13

    Topics: Adenine; Amino Acid Sequence; Animals; Base Composition; Base Sequence; Binding Sites; DNA; Free Radicals; Histones; Hydroxides; Hydroxyl Radical; Male; Molecular Sequence Data; Nucleic Acid Conformation; Sea Urchins; Spermatozoa; Thymine

1989
The unusual conformation adopted by the adenine tracts in kinetoplast DNA.
    Cell, 1987, Mar-27, Volume: 48, Issue:6

    Topics: Adenine; Animals; Base Sequence; Crithidia; DNA, Circular; DNA, Kinetoplast; Hydroxides; Hydroxyl Radical; Models, Molecular; Nucleic Acid Conformation; Thermodynamics

1987
DNA damage in human respiratory tract epithelial cells: damage by gas phase cigarette smoke apparently involves attack by reactive nitrogen species in addition to oxygen radicals.
    FEBS letters, 1995, Nov-20, Volume: 375, Issue:3

    Topics: Adenine; Bronchi; Cell Line; DNA; DNA Damage; Epithelium; Guanine; Humans; Hydroxyl Radical; Hypoxanthine; Hypoxanthines; Smoke; Smoking; Xanthine; Xanthines

1995
Induction of base damage in DNA solutions by ultrasonic cavitation.
    Free radical biology & medicine, 1995, Volume: 18, Issue:2

    Topics: Adenine; Animals; Cattle; Cytosine; DNA Damage; Free Radicals; Gas Chromatography-Mass Spectrometry; Hydrogen Peroxide; Hydroxyl Radical; Purines; Pyrimidines; Thymine; Ultrasonics

1995
Interaction of mithramycin with isolated GC and CG sites.
    Journal of molecular recognition : JMR, 1994, Volume: 7, Issue:3

    Topics: Adenine; Base Sequence; Binding Sites; Carbohydrate Sequence; Cytosine; Deoxyribonuclease I; DNA; Electrophoresis, Polyacrylamide Gel; Guanine; Hydroxyl Radical; Molecular Sequence Data; Molecular Structure; Plicamycin; Thymine

1994
Replication of DNA templates containing the alpha-anomer of deoxyadenosine, a major adenine lesion produced by hydroxyl radicals.
    Biochemistry, 1994, Jun-14, Volume: 33, Issue:23

    Topics: Adenine; Base Sequence; Deoxyadenosines; DNA; DNA Damage; DNA Primers; DNA Replication; Escherichia coli; Hydroxyl Radical; Molecular Sequence Data; Templates, Genetic

1994
How the structure of an adenine tract depends on sequence context: a new model for the structure of TnAn DNA sequences.
    Biochemistry, 1993, Jan-12, Volume: 32, Issue:1

    Topics: Adenine; Base Sequence; Deoxyribonuclease HindIII; Deoxyribonucleases, Type II Site-Specific; DNA; Electrophoresis, Polyacrylamide Gel; Fourier Analysis; Hydroxides; Hydroxyl Radical; Models, Molecular; Molecular Sequence Data; Repetitive Sequences, Nucleic Acid

1993
Inhibition of hydroxyl radical production by lactobionate, adenine, and tempol.
    Free radical biology & medicine, 1995, Volume: 19, Issue:5

    Topics: Adenine; Adenosine; Antioxidants; Bicarbonates; Cardioplegic Solutions; Cyclic N-Oxides; Disaccharides; HEPES; Hydroxyl Radical; Kinetics; Phosphates; Spin Labels; Superoxides

1995
A novel DNA N-glycosylase activity of E. coli T4 endonuclease V that excises 4,6-diamino-5-formamidopyrimidine from DNA, a UV-radiation- and hydroxyl radical-induced product of adenine.
    Mutation research, 1996, Jan-02, Volume: 362, Issue:1

    Topics: Adenine; Animals; Cattle; Deoxyribonuclease (Pyrimidine Dimer); DNA; DNA Damage; DNA Glycosylases; DNA Repair; Endodeoxyribonucleases; Gamma Rays; Hydroxyl Radical; N-Glycosyl Hydrolases; Oxidative Stress; Pyrimidines; Substrate Specificity; Ultraviolet Rays; Viral Proteins

1996
Adenosine deaminase inhibition prevents free radical-mediated injury in the postischemic heart.
    The Journal of biological chemistry, 1996, Apr-26, Volume: 271, Issue:17

    Topics: Adenine; Adenine Nucleotides; Adenosine Deaminase Inhibitors; Animals; Coronary Circulation; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Female; Free Radicals; Hydroxyl Radical; Myocardial Ischemia; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxides; Xanthine Oxidase

1996
Initiator protein pi can bind independently to two domains of the gamma origin core of plasmid R6K: the direct repeats and the A+T-rich segment.
    Nucleic acids research, 1996, May-15, Volume: 24, Issue:10

    Topics: Adenine; Base Sequence; Binding Sites; Deoxyribonuclease EcoRI; Deoxyribonuclease I; Deoxyribonucleases, Type II Site-Specific; DNA; DNA Footprinting; DNA Helicases; DNA-Binding Proteins; Hydroxyl Radical; Molecular Sequence Data; Plasmids; Repetitive Sequences, Nucleic Acid; Thymine; Trans-Activators

1996
Structural distortions induced by integration host factor (IHF) at the H' site of phage lambda probed by (+)-CC-1065, pluramycin, and KMnO4 and by DNA cyclization studies.
    Biochemistry, 1996, Aug-20, Volume: 35, Issue:33

    Topics: Adenine; Aminoglycosides; Anti-Bacterial Agents; Bacterial Proteins; Bacteriophage lambda; Base Sequence; Consensus Sequence; DNA; DNA Footprinting; DNA-Binding Proteins; DNA, Circular; Duocarmycins; Hydroxyl Radical; Indoles; Integration Host Factors; Leucomycins; Molecular Probes; Molecular Sequence Data; Nucleic Acid Conformation; Potassium Permanganate

1996
Reactive oxygen species modified thymine and poly(dT) present unique epitope for human anti-DNA autoantibodies.
    Immunology letters, 1997, Volume: 58, Issue:2

    Topics: Adenine; Animals; Antibodies, Antinuclear; Antibody Specificity; Autoimmune Diseases; Cattle; Enzyme-Linked Immunosorbent Assay; Epitopes; Humans; Hydroxyl Radical; Lupus Erythematosus, Systemic; Poly A; Poly T; Thymine

1997
Compression of the DNA minor groove is responsible for termination of DNA synthesis by HIV-1 reverse transcriptase.
    Journal of molecular biology, 1999, Jan-22, Volume: 285, Issue:3

    Topics: 2-Aminopurine; Adenine; Base Sequence; DNA; DNA, Viral; HIV Reverse Transcriptase; HIV-1; Hydroxyl Radical; Molecular Sequence Data; Mutation; Nucleic Acid Conformation; RNA-Directed DNA Polymerase

1999
Generation of hydroxyl radical by photolysis of mercaptopyridine N-oxides: application to redox chemistry of purines.
    Methods in enzymology, 1999, Volume: 300

    Topics: Adenine; Chromatography, High Pressure Liquid; Electron Spin Resonance Spectroscopy; Hydroxyl Radical; Oxidation-Reduction; Photolysis; Purines; Pyridines; Thiones; Xanthine

1999
DNA sequence recognition by a novel series of minor groove-binding ligands.
    Anti-cancer drug design, 1999, Volume: 14, Issue:3

    Topics: Adenine; Base Pairing; Base Sequence; Benzene Derivatives; Binding Sites; Deoxyribonuclease I; DNA; DNA Footprinting; Hydroxyl Radical; Ligands; Molecular Sequence Data; Nucleic Acid Conformation; Plasmids; Substrate Specificity; Thymidine

1999
Single 8-oxo-guanine and 8-oxo-adenine lesions induce marked changes in the backbone structure of a 25-base DNA strand.
    Proceedings of the National Academy of Sciences of the United States of America, 2000, Nov-07, Volume: 97, Issue:23

    Topics: Adenine; DNA; DNA Damage; Guanine; Hydroxyl Radical; Multivariate Analysis; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Spectroscopy, Fourier Transform Infrared

2000
A detailed interpretation of OH radical footprints in a TBP-DNA complex reveals the role of dynamics in the mechanism of sequence-specific binding.
    Journal of molecular biology, 2000, Nov-17, Volume: 304, Issue:1

    Topics: Adenine; Adenoviruses, Human; Arabidopsis; Base Sequence; Binding Sites; Computer Simulation; Crystallography, X-Ray; Dimerization; DNA; DNA-Binding Proteins; Genes, Viral; Hydrogen Bonding; Hydroxyl Radical; Models, Molecular; Nucleic Acid Conformation; Protein Conformation; Protein Footprinting; Solvents; Substrate Specificity; TATA Box; TATA-Box Binding Protein; Thermodynamics; Transcription Factors

2000
Age-related radical-induced DNA damage is linked to prostate cancer.
    Cancer research, 2001, Aug-15, Volume: 61, Issue:16

    Topics: Adenine; Age Factors; Cell Transformation, Neoplastic; DNA; DNA Damage; DNA, Neoplasm; Gas Chromatography-Mass Spectrometry; Guanine; Humans; Hydroxyl Radical; Logistic Models; Male; Middle Aged; Models, Biological; Prostate; Prostatic Neoplasms; Pyrimidines

2001
Activity of (-)-epigallocatechin 3-O-gallate against oxidative stress in rats with adenine-induced renal failure.
    Journal of agricultural and food chemistry, 2004, Apr-07, Volume: 52, Issue:7

    Topics: Adenine; Animals; Antioxidants; Blood Urea Nitrogen; Catechin; Creatinine; Hydroxyl Radical; Kidney Failure, Chronic; Male; Methylguanidine; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Wistar

2004
Derivatization for LC-electrospray ionization-MS: a tool for improving reversed-phase separation and ESI responses of bases, ribosides, and intact nucleotides.
    Analytical chemistry, 2004, May-15, Volume: 76, Issue:10

    Topics: Adenine; Anhydrides; Benzoates; Buffers; Chromatography, Liquid; Cytokinins; Glycosides; Hydrophobic and Hydrophilic Interactions; Hydroxyl Radical; Molecular Weight; Nucleotides; Plant Extracts; Propionates; Ribose; Spectrometry, Mass, Electrospray Ionization; Terpenes

2004
How does modification of adenine by hydroxyl radical influence the stability and the nature of stacking interactions in adenine-cytosine complex?
    Journal of molecular modeling, 2009, Volume: 15, Issue:6

    Topics: Adenine; Algorithms; Cytosine; DNA; Hydroxyl Radical; Models, Chemical; Nucleic Acid Conformation; Static Electricity; Thermodynamics

2009
Hydroxyl radical reactions with adenine: reactant complexes, transition states, and product complexes.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2010, Oct-18, Volume: 16, Issue:39

    Topics: Adenine; Algorithms; Hydroxyl Radical; Models, Theoretical; Molecular Structure

2010
Chelation of lysosomal iron protects dopaminergic SH-SY5Y neuroblastoma cells from hydrogen peroxide toxicity by precluding autophagy and Akt dephosphorylation.
    Toxicological sciences : an official journal of the Society of Toxicology, 2011, Volume: 123, Issue:2

    Topics: Adenine; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Cell Line, Tumor; Deferoxamine; Free Radicals; Gene Silencing; Humans; Hydrogen Peroxide; Hydroxyl Radical; Lysosomes; Membrane Proteins; Mitochondria; Neuroblastoma; Oncogene Protein v-akt; Oxidants; Phosphorylation; RNA, Small Interfering; Siderophores

2011
Silibinin induced-autophagic and apoptotic death is associated with an increase in reactive oxygen and nitrogen species in HeLa cells.
    Free radical research, 2011, Volume: 45, Issue:11-12

    Topics: Acetylcysteine; Adenine; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Caspase 3; Cell Survival; Glutathione; HeLa Cells; Humans; Hydroxyl Radical; Membrane Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Reactive Nitrogen Species; Reactive Oxygen Species; Silybin; Silymarin

2011
Kinetics and Thermodynamics of the Reaction between the (•)OH Radical and Adenine: A Theoretical Investigation.
    The journal of physical chemistry. A, 2015, Jun-18, Volume: 119, Issue:24

    Topics: Adenine; Carbon; Hydrogen; Hydroxyl Radical; Kinetics; Models, Chemical; Models, Molecular; Thermodynamics

2015
Insight into the Mechanism of the Initial Reaction of an OH Radical with DNA/RNA Nucleobases: A Computational Investigation of Radiation Damage.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2015, Dec-01, Volume: 21, Issue:49

    Topics: Adenine; Computer Simulation; DNA; Guanine; Hydroxyl Radical; Kinetics; RNA; Thymine; Uracil

2015
The Effect of Solvation on the Radiation Damage Rate Constants for Adenine.
    Chemphyschem : a European journal of chemical physics and physical chemistry, 2016, Oct-05, Volume: 17, Issue:19

    Topics: Adenine; DNA Damage; Hydroxyl Radical; Quantum Theory; Solubility; Thermodynamics

2016
UV-Induced Adenine Radicals Induced in DNA A-Tracts: Spectral and Dynamical Characterization.
    The journal of physical chemistry letters, 2016, Oct-06, Volume: 7, Issue:19

    Topics: Adenine; DNA; Electron Spin Resonance Spectroscopy; Free Radicals; Hydroxyl Radical; Photons; Quantum Theory; Spectrophotometry; Ultraviolet Rays

2016
Mechanism of the OH Radical Addition to Adenine from Quantum-Chemistry Determinations of Reaction Paths and Spectroscopic Tracking of the Intermediates.
    The Journal of organic chemistry, 2017, 01-06, Volume: 82, Issue:1

    Topics: Adenine; Hydroxyl Radical; Nucleic Acid Conformation; Pyrimidines; Quantum Theory

2017
Real Time Normalization of Fast Photochemical Oxidation of Proteins Experiments by Inline Adenine Radical Dosimetry.
    Analytical chemistry, 2018, 11-06, Volume: 90, Issue:21

    Topics: Adenine; Fibrinopeptide B; Hydroxyl Radical; Myoglobin; Oxidation-Reduction; Protein Footprinting; Spectrophotometry, Ultraviolet; Ultraviolet Rays

2018
Effects of organic matter and alkalinity on the ozonation of antiviral purine derivatives as exemplary micropollutant motif.
    Water research, 2023, Sep-01, Volume: 243

    Topics: Adenine; Bicarbonates; Hydroxyl Radical; Oxidation-Reduction; Ozone; Purines; Water Pollutants, Chemical; Water Purification

2023