adenine has been researched along with guanine in 3167 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1136 (35.87) | 18.7374 |
| 1990's | 405 (12.79) | 18.2507 |
| 2000's | 785 (24.79) | 29.6817 |
| 2010's | 747 (23.59) | 24.3611 |
| 2020's | 94 (2.97) | 2.80 |
| Authors | Studies |
|---|---|
| Duffy, EM; Jorgensen, WL | 1 |
| Carlson, EE; Goswami, M; Wilke, KE | 1 |
| Housset, P; Nagy, M; Schwencke, J | 1 |
| Di Prisco, G | 1 |
| Gehrke, CW; Lakings, DR; Waalkes, TP | 1 |
| Lakings, DB; Mrochek, JE; Waalkes, TP | 1 |
| Divekar, AY | 1 |
| Trevelyan, WE | 1 |
| Housset, P; Nagy, M | 1 |
| Beck, MT; Dózsa, L | 1 |
| Wong, JL; Zady, MF | 1 |
| Schnedl, W | 1 |
| Tsai, WC; Westby, CA | 1 |
| Berech, J; Keegan, FP | 1 |
| Magill, CW; Magill, JM | 1 |
| Stuart, WD; Woodward, DO | 1 |
| Irvin, AD; Stagg, DA | 1 |
| Pendyala, L; Wellman, AM | 1 |
| McBurney, MW; Whimore, GF | 1 |
| Davison, CL; Gilbert, RM; Papirmeister, B; Rowland, S | 1 |
| Plagemann, PG; Zylka, JM | 1 |
| Hayano, K; Ishida, N; Mizuno, K; Sakaguchi, K; Tsujino, M | 1 |
| Jarman, M; Lawley, PD; Orr, DJ | 1 |
| Arimura, H | 1 |
| Visser, DW; Yang, YH | 1 |
| Albach, RA; Booden, T; Boonlayangoor, P; Stern, ML | 1 |
| Bornkamm, GW; Delius, H | 1 |
| Sivan, O; Sperling, O; Zoref, E | 1 |
| Sperling, O; Zoref-Shani, E | 1 |
| McGhee, JD; von Hippel, PH | 1 |
| Budowsky, EI; Ivanchenko, VA; Simukova, NA; Titschenko, AI; Wulfson, NS | 1 |
| Gilbert, W; Maxam, AM | 1 |
| Burlingame, AL; Calvin, M; Meehan, T; Straub, KM | 1 |
| Baisch, H; Garbrecht, M; Heller-Schöch, G; Leifer, W; Schöch, G | 1 |
| Felsenfeld, G; McGhee, JD | 1 |
| Hovi, T; Raivio, KO | 1 |
| Ko, RC; Wong, PC | 1 |
| Burridge, PW; Henderson, JF; Woods, RA | 3 |
| Kocharian, ShM | 1 |
| Beabealashvilli, R; Melnikova, AF; Mirzabekov, AD | 1 |
| Chanishvili, TG; Debov, SS; Nikol'skaia, II; Tediashvili, MI | 1 |
| Chang, SH; Chia, LL; Gupta, RC; Randerath, E; Randerath, K | 1 |
| Caldas, RD; Ceron, CR; Felix, CR; Mundim, MH; Roitman, I | 1 |
| Armbruster, AM; Pullman, A | 1 |
| de Bruyn, CH; Oei, TL | 2 |
| Bongaerts, GP; Peters, AL; Sin, IL; Vogels, GD | 1 |
| Ikenaga, M; Ishii, Y; Takebe, H | 1 |
| Ikenaga, M; Kakunaga, T | 1 |
| Donis-Keller, H; Gilbert, W; Maxam, AM | 1 |
| Milner, JA | 1 |
| Liszewski, MK; Munns, TW; Oberst, RJ; Sims, HF | 1 |
| Akintonwa, A; Auditore, JV; Ballard, BR; Green, LD | 1 |
| Müller, MM; Pischek, G; Scheiner, O; Stemberger, H; Wiedermann, G | 1 |
| McGavin, S | 2 |
| Thielmann, HW | 1 |
| Clifford, AJ; Crane, RT; Ericson, KA; Ho, CY; Miller, KV; Savaiano, DA | 1 |
| Bohácek, J | 1 |
| Simashkevich, PM; Stotish, RL; Wang, CC | 1 |
| Crathorn, AR; Shooter, KV; Warren, W | 1 |
| Geerdes, HA; Hilbers, CW | 1 |
| Craig, AW; Curtin, NJ; Margison, GP; Snell, K | 1 |
| Bolte, J; Demuynck, C; Fournié-Zaluski, MC; Lhomme, J; Roques, BP | 1 |
| Bakay, B; Francke, U; Nissinen, E; Nyhan, WL; Sweetman, L | 1 |
| Ciompi, ML; Lucacchini, A; Mazzoni, MR; Segnini, D | 1 |
| Birnboim, HC; Mitchel, RE | 1 |
| Brown, DD; Fedoroff, NV | 1 |
| Mayfield, JE; McKenna, JF | 1 |
| Baisch, H; Heller-Schöch, G; Schöch, G; Winkler, K | 1 |
| Iwahashi, H; Kyogoku, Y | 1 |
| Ferm, VH; Willhite, CC | 1 |
| Hui, G; Pegg, AE | 1 |
| Blagoĭ, IuP; Gladchenko, GO; Sorokin, VA; Valeev, VA | 1 |
| Blagoĭ, IuP; Radchenko, ED; Sheina, GG; Verkin, BI | 1 |
| Patterson, D; Tu, AS | 1 |
| Dewey, VC; Kidder, GW; Nolan, LL | 1 |
| Goldblum, A; Perahia, D; Pullman, A | 1 |
| Kenny, GE; McIvor, RS | 1 |
| Fraser, AR; Ganoza, MC; Neilson, T | 1 |
| Campbell, JW; Carnes, DL | 1 |
| Akutsu, H; Kawano, K; Kyogoku, Y; Watanabe, M; Yu, BS | 1 |
| Dousset, N; Douste-Blazy, L; Solera, ML; Valdiguie, P | 1 |
| Hui, G; Pegg, AE; Rogers, KJ | 1 |
| Bücheler, J; Cooper, HK; Kleihues, P; Swenberg, JA | 1 |
| Ichihara, A; Konishi, Y | 1 |
| Lawley, PD; Warren, W | 3 |
| Hutchinson, F; Krasin, F; Ley, RD; Person, S | 1 |
| Benson, CE; Gots, JS | 1 |
| Hershfield, MS; Seegmiller, JE | 2 |
| Jyssum, K; Jyssum, S | 1 |
| Krämer, J | 1 |
| Nagao, M; Sugimura, T | 1 |
| Harriman, PD; Holden, JA; Wall, JD | 1 |
| Barr, EW; Issaq, HJ | 1 |
| Bolte, J; Demuynck, C; Lhomme, J | 1 |
| Balis, ME; Maschio, FA; Tscherne, JS; Wainfan, E | 1 |
| Salas, CE; Sellinger, OZ | 1 |
| Carpenter, JM; Kassanis, B; White, RF | 1 |
| Barr, EW; Issaq, HJ; Zielinski, WL | 1 |
| Raivio, KO; Rovamo, L; Smith, C | 1 |
| Inubushi, T; Kyogoku, Y; Morishima, I; Yonezawa, T | 1 |
| Cavallone, F; Clementi, E; Scordamaglia, R | 1 |
| Kochakian, CD; Roberts, P | 1 |
| Lancelot, G | 1 |
| Daune, MP; Fuchs, RP; Lang, MC | 1 |
| Christman, CL; McKee, JR; O'Brien, WD; Wang, SY | 1 |
| Margison, GP; Margison, JM; Montesano, R | 2 |
| Kekomäki, MP; Raivio, KO; Rovamo, LM; Smith, CM | 1 |
| Robin, J; Rodrigue, A | 1 |
| Seegmiller, JE; Skaper, SD | 1 |
| Schnabl, H | 1 |
| Kilbourne, ED; Palese, P; Ritchey, MB | 1 |
| Giessner-Prettre, C; Pullman, B | 2 |
| Ianson, IK; Sukhodub, LF; Verkin, BI | 1 |
| Budowsky, EI; Mazurenko, NN; Tikchonenko, TI | 1 |
| Desostoa, A; Levinson, JW; Liebes, LF; McCormick, JJ | 1 |
| Perry, RP; Schibler, U | 1 |
| Desai, TS; Sane, PV; Tatake, VG | 1 |
| Raska, K; Varricchio, F | 1 |
| Badenoch-Jones, P; Buttery, PJ | 1 |
| Brown, DD; Carroll, D | 1 |
| Bresil, H; Margison, GP; Margison, JM; Montensano, R | 1 |
| Sekiya, M; Suzuki, J; Terao, Y | 1 |
| Brox, LW; Henderson, JF; Hryniuk, WM; Tamaoki, T | 1 |
| Henderson, JF; Smith, CM; Snyder, FF; Zombor, G | 1 |
| Naimy, NK; Scribner, JD | 1 |
| Campbell, JW; Vorhaben, JE; Wong, L | 1 |
| Fouts, DL; Manning, JE; Wolstenholme, DR | 1 |
| Seiler, JP | 1 |
| Elton, RA | 1 |
| Guilford, H; Mosbach, K | 1 |
| Blinov, MN; Egorova, VA | 1 |
| Bakanova, NV; Leutskií, KM | 1 |
| Frei, JV; Lawley, PD | 1 |
| Agarwal, DP; Goedde, HW; Schloot, W; Singh, S; Willers, I | 1 |
| Drach, JC; Schwartz, PM | 1 |
| Gruber, BA; Leonard, NJ; Mutai, K | 1 |
| Caneva, R; Hanania, N; Harel, J; Tapiero, H | 1 |
| Blume, AJ; Foster, CJ | 1 |
| Bańkowski, E; Gindzieński, A; Pawlicka, E; Rzeczycki, W | 1 |
| Mel'gunov, VI | 1 |
| Brox, LW; Fraser, JH; Henderson, JF; McCoy, EE; Meyers, H | 1 |
| Eguchi, Y; Ochi, D; Yashima, S | 1 |
| Glick, JM; Leboy, PS; Ross, S | 1 |
| Margison, GP; O'Connor, PJ | 1 |
| Kaspersen, FM; Pandit, UK | 1 |
| Clerx, JP; Horzinek, MC; van der Zelist, BA | 1 |
| Barnett, WA; Jones, EC; Wise, ML | 1 |
| Kurisu, M; Nozu, Y; Ohno, T; Okada, Y | 1 |
| Henderson, JF; Smith, CM | 1 |
| Beland, FA; Brookes, P; Harvey, RG; Osborne, MR; Tarmy, EM; Thompson, MH | 1 |
| Chilson, OP | 1 |
| Close, DM; Hole, EO; Nelson, WH; Sagstuen, E | 1 |
| Andrei, G; De Clercq, E; Desmyter, J; Goubau, P; Snoeck, R | 1 |
| Awan, AR; de la Fuente, R; Field, HJ | 1 |
| Brown, T; Ebel, S; Lane, A; Martin, SR | 1 |
| Antonarakis, SE; Economou, EP; Maumenee, IH; Zhu, DP | 1 |
| Foley, BT; Moehring, JM; Moehring, TJ | 1 |
| Coates, PM; Hale, DE; Rinaldo, P; Tanaka, K; Yokota, I | 1 |
| Nese, C; Schuchmann, MN; Von Sonntag, C; Yuan, Z | 1 |
| Baysal, E; Beris, P; Dimovski, AJ; Huisman, TH; Kitundu, MN; Kutlar, F; Lanclos, KD; Oner, C | 1 |
| Izuta, S; Kitagawa, M; Kojima, K; Shimada, N; Suzuki, M; Yoshida, S | 1 |
| Brown, T; Guy, A; Hunter, WN; Leonard, GA; Téoule, R | 1 |
| Berman, HM; Cohen, D; Schneider, B | 1 |
| Görner, H; Gurzadyan, GG | 1 |
| Brown, T; Ebel, S; Lane, AN | 1 |
| Essigmann, JM; Esteve, A; Kuziemko, GM; Morningstar, ML; Wood, ML | 1 |
| Davidson, M; Dean, JC; Haites, NE; Kelly, KF; Little, S; Miedzybrodzka, ZH; Shrimpton, AE | 1 |
| Inana, G; Kennaway, NG; Mashima, Y; Weleber, RG | 1 |
| Davey, RA; Duffield, GA; Ey, PL | 1 |
| Becka, R; Reilly, KE; Thomas, GJ | 1 |
| Andrews, NC; Higgs, DR; Orkin, SH; Strauss, EC | 1 |
| Alexiou, M; Leese, HJ | 1 |
| Rao, SN | 1 |
| Baralle, FE; Casari, G; Melo, C; Tuteja, N; Tuteja, R | 1 |
| Komarov, VM; Konoplev, GG; Polozov, RV | 1 |
| Bhan, P; Cushman, CD; Miller, PS; Trapane, TL | 1 |
| Elfferich, P; Laird-Offringa, IA; van der Eb, AJ | 1 |
| Haimanot, R; Malins, DC | 1 |
| Ishii, T; Karasawa, Y; Kubota, T | 1 |
| Holý, A; Hrebabecký, H; Merta, A; Otmar, M; Rosenberg, I; Trávnícek, M; Votruba, I | 1 |
| Cerný, J; Holý, A; Hrebabecký, H; Merta, A; Otmar, M; Rosenberg, I; Sedivá, K; Veselý, J; Vlach, J; Votruba, I | 1 |
| Chen, EC; Chen, ES; Ehdaie, S; Robinson, JM; Wentworth, WE; Wiley, JR | 1 |
| Cinci, G; Di Stefano, A; Marinello, E; Pagani, R; Pizzichini, M; Vannoni, D | 1 |
| Camiña, F; Castro-Gago, M; Lojo, S; Rodríguez-Núñez, A; Rodríguez-Segade, S | 1 |
| Barch, DH; Brasitus, TA; Carney, WP; Iannaccone, PM; Jacoby, RF; Radosevich, JA | 1 |
| Andresen, B; Blakemore, AI; Bolund, L; Curtis, D; Engel, PC; Gregersen, N; Kølvraa, S; Winter, V | 1 |
| Kojima, M; Okuda, H; Suzuki, M; Tada, M; Watabe, T | 1 |
| Araullo-Cruz, T; De Clercq, E; Erzurum, S; Gordon, YJ; Romanowski, E; Seaberg, L; Tolman, R | 1 |
| Brown, DM; Lin, PK | 1 |
| Bhatia, G; Brumbaugh, AE; Hung, LF; Hung, PP; Marion, PL; Norbeck, DW; Plattner, JJ; Robinson, WS | 1 |
| Ahnström, G; Eizirik, DL; Sandler, S; Welsh, M | 1 |
| Chatterjee, A; Henle, E; Holley, WR; Roots, R | 1 |
| Li, Y; Wilson, WD; Zon, G | 2 |
| Cushnir, JR; Farmer, PB; Lamb, JH; Parry, A | 1 |
| Correa, P; Glogowski, J; Stillwell, WG; Tannenbaum, SR; Wishnok, JS; Xu, HX | 1 |
| De Clercq, E | 3 |
| Chakravarti, D; Ibeanu, GC; Mitra, S; Tano, K | 1 |
| Kamiya, H; Miura, K; Nishimura, S; Ohtomo, N; Ohtsuka, E | 1 |
| Cahill, DS; Cheng, KC; Dosanjh, MK; Loeb, LA; Preston, BD; Singer, B | 1 |
| Berninger, TA; Kormann, BA; Leo-Kottler, B; Schuster, H | 1 |
| Cheung, KS; Hedstrom, L; Wang, CC | 1 |
| Anin, MF; Corda, Y; Job, C; Job, D; Leng, M | 1 |
| Correa, P; Glogowski, J; Montes, G; Stillwell, WG; Tannenbaum, SR; Wishnok, JS; Xu, HX; Zavala, D | 1 |
| Baran, N; Lapidot, A; Manor, H | 1 |
| Maeda, M; Yoshida, A | 1 |
| Gross, CJ; Savaiano, DA | 1 |
| Bolt, HM; Foest, U; Gansewendt, B; Hallier, E; Peter, H; Xu, D | 1 |
| Kant, J; Reed, JC; Tanaka, S | 1 |
| Zhang, CT; Zhang, R | 1 |
| Panigrahi, GB; Walker, IG | 1 |
| Bernelot-Moens, C; Glickman, BW; Gordon, AJ | 1 |
| Ballinger, SW; Lezza, AM; Lott, MT; Seibel, P; Shoffner, JM; Wallace, DC | 1 |
| Bottiglieri, T; Chanarin, I; Deacon, R; Lumb, M; Perry, J | 1 |
| Abbondandolo, A; Bonatti, S; Cercignani, G; Rocco, M | 1 |
| Akli, S; Chelly, J; Gandy, S; Kahn, A; Mezard, C; Poenaru, L | 1 |
| Cons, BM; Fox, KR | 1 |
| Cuipa, MJ; Ip, MS; Lu, AL; Shanabruch, WG | 1 |
| Kim, CU; Luh, BY; Martin, JC | 1 |
| Akhrem, AA; Aslanian, VM; Dalian, EB; Haroutiunian, SG | 1 |
| Henderson, L; O'Donovan, MR; Waters, R; Wilcox, P | 1 |
| Booth, ED; Brown, T; Leonard, GA | 1 |
| Akman, SA; Dizdaroglu, M; Doroshow, JH | 1 |
| Berman, J; Lefebvre, PA; Petracek, ME; Silflow, CD | 1 |
| Berdal, KG; Bjelland, S; Bjørås, M; Seeberg, E | 1 |
| Carlson, RM; Samanta, AK; Xue, WL | 1 |
| Csanády, G; Peter, H | 1 |
| Hannink, M; Temin, HM | 1 |
| Barr, M; Bonadio, J; Ramirez, F | 1 |
| Kim, SH; Pearlman, DA | 1 |
| Doi, M; Inoue, M; Ishida, T; Segawa, K; Ueda, H | 1 |
| Broder, S; Fine, RL; Hayashi, S; Matsukura, M; Mitsuya, H; Norbeck, DW; Plattner, JJ; Rosenbrook, W | 1 |
| Clement, J; Erickson, J; Hayashi, S; Herrin, T; Kern, E; Norbeck, DW; Plattner, JJ; Rosenbrook, W; Sham, H; Swanson, R | 1 |
| Bethlenfalvay, NC; Chadwick, E; Lima, JE; White, JC | 1 |
| Kontusaari, S; Kuivaniemi, H; Prockop, DJ; Sabol, C; Tromp, G; Zhao, MJ | 1 |
| Christophe, D; Compère, T; Gérard, C; Vassart, G | 1 |
| Li, BF; Neidle, S; Sanderson, MR; Skelly, JV; Swann, PF; Tickle, IJ; Webster, GD | 1 |
| Weiner, AM; Zhuang, Y | 1 |
| Glässer, D; Iwig, M | 1 |
| Barankiewicz, J; Cohen, A | 3 |
| Kalaizis, A; Rowe, PB | 1 |
| Jouany, JP; Lassalas, B; Ushida, K | 1 |
| Klaar, J; Kula, MR | 1 |
| Kato, S; Kitada, T; Morichi, T; Suzuki, I; Yano, N | 1 |
| Cheong, C; Clark, LB; Tinoco, I; Williams, AL | 1 |
| Braymer, HD; Shinabarger, DL | 1 |
| Laib, RJ | 1 |
| Krenitsky, TA; LaFon, SW; Miller, RL; Miller, WH; Nelson, DJ | 1 |
| Harris, HF; Huang, HJ; Huisman, TH; Kutlar, F; Stoming, TA | 1 |
| Ebbole, DJ; Zalkin, H | 1 |
| Eadie, JS; Farrance, IK; Ivarie, R | 1 |
| Fujioka, H; Nishiyama, Y; Shimada, N; Takahashi, K; Yamada, Y; Yamamoto, N | 1 |
| Dervan, PB; Griffin, LC | 1 |
| Hüttermann, J; Sieber, K | 1 |
| Gehring, AG; Hudson, RD; Hyde, CT; Jurman, LA; Masselink, JK; Trumbore, CN | 1 |
| Boyd, MR; Harnden, MR; Jarvest, RL; Sutton, D; Vere Hodge, RA | 2 |
| Leng, M; Marrot, L; Schwartz, A | 1 |
| Beck, J; Ullman, B | 1 |
| Khramtsova, SN; Pimenov, AM; Potapova, GI; Shapot, VS; Tikhonov, IuV; Toguzov, RT | 1 |
| Bigger, CA; Dipple, A; Jerina, DM; Strandberg, J; Yagi, H | 1 |
| Akiyama, M; Horiuchi, T; Maki, H; Sekiguchi, M | 1 |
| Au, KG; Clark, S; Miller, JH; Modrich, P | 1 |
| Drinkwater, NR; Eckert, KA; Ingle, CA | 1 |
| Misra, TN; Sarkar, D | 2 |
| Hedstrom, L; Wang, CC | 1 |
| Brown, TC; Corman, N; Jiricny, J; Rudkin, BB | 1 |
| Booth, ED; Brown, T; Chambers, J; Leonard, GA | 1 |
| Hanawalt, PC; Scicchitano, DA | 1 |
| Beaumont, C; de Rooij, F; Deybach, JC; Grandchamp, B; Nordmann, Y; Picat, C; Wilson, P | 1 |
| Nishiyama, Y; Shimada, N; Takahash, K; Yamamoto, N | 1 |
| Lo, HS; Wang, CC | 1 |
| Hoffman, R; Jayaram, HN; Lapis, E; Natsumeda, Y; Tricot, GJ; Weber, G; Yamada, Y; Yamaji, Y | 1 |
| Bochert, G; Neubert, D; Platzek, T; Rahm, U | 1 |
| Clark, EA; Fox, MS; Radicella, JP | 1 |
| Holmes, EW; Manfredi, JP | 1 |
| Brennan, CA; Gumport, RI; Van Cleve, MD | 2 |
| Brandes, R; Ehrenberg, A | 1 |
| Hua, M; Korkowski, PM; Vince, R | 1 |
| Téoule, R | 1 |
| Au, KG; Cabrera, M; Miller, JH; Modrich, P | 1 |
| Fliess, A; Pingoud, A; Seela, F; Wolfes, H | 1 |
| Berens, RL; Marr, JJ | 1 |
| Nygaard, P; Saxild, HH | 1 |
| Ghomi, M; Letellier, R; Taillandier, E | 1 |
| Ohno, S | 1 |
| Katsaros, N; Tselepi-Kalouli, E | 1 |
| Saito, T; Yamaguchi, J | 1 |
| Poltev, VI; Steinberg, SV | 1 |
| Bonekamp, F; Jensen, KF | 1 |
| Guimarães, RC; Gutteridge, WE | 2 |
| Domin, BA; Mahony, WB; Zimmerman, TP | 1 |
| Domin, BA; Mahony, WB; McConnell, RT; Zimmerman, TP | 1 |
| Gross, CJ; Savaiano, DA; Stiles, JE | 1 |
| Aronow, B; Hollingsworth, P; McCartan, K; Patrick, J; Toll, D; Ullman, B | 1 |
| Duan, DS; Sadée, W | 1 |
| Lawrence, CW; Nisson, PE | 1 |
| Jiricny, J; Martin, D; Ubasawa, A; Wood, SG | 1 |
| Fix, DF; Glickman, BW | 1 |
| Barbin, A; Bartsch, H | 1 |
| Murray, V | 1 |
| McCartan, K; Patrick, J; Ullman, B | 1 |
| Baba, M; De Clercq, E; Mori, S; Shigeta, S | 1 |
| Backendorf, C; Kaina, B; Thielmann, HW; Van de Putte, P; Van Zeeland, AA | 1 |
| Di Stefano, A; Marinello, E; Pizzichini, M | 1 |
| Bailey, E; Farmer, PB; Shuker, DE | 1 |
| Franzus, MJ; Malcolm, GB; Pine, L | 1 |
| D'Ambrosio, SM; Wani, AA | 1 |
| Chetsanga, CJ; Mavunga, I | 1 |
| Kennard, O | 1 |
| Kent, S; Ludlum, DB; Mehta, JR | 1 |
| Di Stefano, A; Marinello, E; Pizzichini, M; Pompucci, G | 1 |
| Callis, PR | 1 |
| Everett, DW; Kundu, SK; Shapiro, R; Sodum, RS | 1 |
| Bartsch, H | 1 |
| Adler, S; Doerjer, G; Oesch, F; Rettelbach, R | 1 |
| Linn, S; Samson, L | 1 |
| Phadtare, S; Zemlicka, J | 1 |
| Amarnath, V; Hall, IH; Lee, KH; Rice, GK | 1 |
| Colaço, CB; Harris, G; Irving, W; Lawley, PD; Lydyard, PM; Phillips, E; Roitt, IM | 1 |
| Helland, DE; Kleppe, K; Male, R | 1 |
| Mishra, PC | 1 |
| Goodman, MF; Hopkins, RL; Lasken, R; Mhaskar, DN | 1 |
| Farley, BA; Ohlsson-Wilhelm, BM; Rowley, PT; Rudolph, NS | 1 |
| Jacobsen, SJ; Mangum, JH; Nyhan, WL; Page, T; Robins, RK; Scheele, J; Smejkal, RM | 1 |
| Briscoe, WT; Cotter, LE | 1 |
| Segal, A; Solomon, JJ | 1 |
| Brenci, G; Gedda, L | 1 |
| Jain, SC; Sobell, HM | 1 |
| Haidle, CW; Kuo, MT; Weiss, KK | 1 |
| Wisseman, CL | 1 |
| Bitensky, MW; Keirns, JJ; Wheeler, MA | 1 |
| Burny, A; Marbaix, G | 1 |
| Castellani, PC; Coleman, JO; Shapira, J | 1 |
| Brunfaut, M; Errera, M; Miller-Faurès, A; Szapary-Winckelmans, D | 1 |
| Katagiri, K; Sato, K; Shiratori, O | 1 |
| Priegnitz, A; Sikorska, EJ | 1 |
| Krsmanovic, V; Montreuil, J; Sergeant, A; Verbert, A | 1 |
| Agabian-Keshishian, N; Shapiro, L | 1 |
| Katchalsky, A; Neumann, E; Revzin, A | 1 |
| Yeh, J | 1 |
| Agris, PF; Brown, GM; Spremulli, LL | 1 |
| Constantin, T | 1 |
| Dean, JA | 1 |
| Balwin, RL; Martin, RJ | 1 |
| Doskocil, J; Hradecná, Z; Pillich, J | 1 |
| Chauchard, J; Chauchard, P; Lecoq, R; Mazoué, H | 1 |
| Koide, T; Rabinowitz, M | 1 |
| Omori, M | 1 |
| Adiga, PR; Sarma, PS | 1 |
| Wessman, G; Wessman, GE | 2 |
| Krüger, FW; Rücker, U; Wiessler, M | 1 |
| Benson, PF | 1 |
| Isshiki, G; Oura, T; Tada, K; Uesaki, T | 1 |
| Goth, R; Rajewsky, MF | 2 |
| Pihl, A; Sanner, T | 1 |
| Bishop, JM; Levintow, L; Summers, DF | 1 |
| Matsuzaki, F; Raben, MS | 1 |
| Cook, JB; Wyard, SJ | 1 |
| Bersohn, M; Jones, JB; Niece, GC | 1 |
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| Cotticelli, MG; Hauser, LA; Himes, BE; Ho, ES; Lynch, DR; Mesaros, C; Napierala, JS; Napierala, M; Wang, D; Wilson, RB; Xu, P | 1 |
| Cui, X; Duan, L; Meng, Q; Zhang, C; Zhang, X; Zhao, Y | 1 |
| Bentivoglio, AR; Calabresi, P; Di Tella, S; Lo Monaco, MR; Petracca, M; Piano, C; Silveri, MC; Solito, M; Zinzi, P | 1 |
| Ahn, SH; Jung, CY; Kim, BS; Kim, HW; Kim, SU; Lee, HW; Lee, JI | 1 |
| Brož, B; Huang, SR; Liu, Y; Marek, A; Tureček, F; Wan, J | 1 |
| Mandal, S; Srinivasan, V | 1 |
| Walhidayah, T | 1 |
| Gan, Z; Hua, W; Wu, Y; Zhao, L | 1 |
| Afshar, V; Karimian, R | 1 |
| Dietschreit, JCB; Kussmann, J; Laqua, H; Ochsenfeld, C | 1 |
| Czeleń, P; Jezierska, A; Szefler, B; Wojtkowiak, K | 1 |
| Akahane, T; Inoue, J; Iwata, T; Kisara, N; Kobayashi, T; Masamune, A; Ninomiya, M; Onuki, M; Sano, A; Sato, K; Sato, S; Tsuruoka, M | 1 |
| Altalhi, T; Huang, Y; Penev, ES; Yakobson, BI | 1 |
| Lee, AL; Mooney, DT; Moore, PR | 1 |
| Abramov, G; Pozdnyakova, Y; Shakeev, K; Shestakov, D; Tankibaeva, N; Tusupbekova, M | 1 |
| Huang, Q; Li, S; Liu, X; Tan, C; Wang, S; Yang, H; Ye, H; Zhang, G | 1 |
| Błażej, P; Mackiewicz, D; Mackiewicz, P; Pawlak, K | 1 |
| Bishop, AR; Hillebrand, M; Kalosakas, G; Skokos, C | 1 |
| Basterretxea, FJ; Camiruaga, A; Fernández, JA; Martínez, R; Pinillos, P; Usabiaga, I | 1 |
| Lambropoulos, K; Mantela, M; Simserides, C | 1 |
| Fei, JF; Liang, F; Liu, Y; Qin, W; Zhang, Y; Zheng, S | 1 |
| Angeloni, C; Borghi, C; Cicero, AFG; Di Micoli, V; Fogacci, F; Giovannini, M | 1 |
| Bulko, TV; Kostryukova, LV; Pronina, VV; Shumyantseva, VV | 1 |
| Pavesi, A; Romerio, F | 1 |
| Hua, CX; Lim, CR; New, SY; Ng, JF; Ooi, JSY | 1 |
201 review(s) available for adenine and guanine
| Article | Year |
|---|---|
Structure and variability of human chromosomes analyzed by recent techniques.
Topics: Adenine; Amino Acid Sequence; Chromosomes, Human; Cytidine; Fluorescent Dyes; Guanine; Heterochromatin; Humans; Staining and Labeling; Thymine | 1978 |
Gout and the regulation of purine biosynthesis.
Topics: Adenine; Amidophosphoribosyltransferase; Cell Line; Gout; Guanine; Humans; Hypoxanthines; Kinetics; Phosphoribosyl Pyrophosphate; Purine Nucleotides; Purines | 1976 |
Molecular biology of the carcinogen, 4-nitroquinoline 1-oxide.
Topics: 4-Nitroquinoline-1-oxide; Adenine; Animals; Bacteria; Bacteriophages; Base Sequence; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Chemical Phenomena; Chemistry; Chromosome Aberrations; DNA; DNA Repair; Guanine; Immunity; Mice; Mitosis; Mutagens; Neoplasms, Experimental; Nitroquinolines; Oncogenic Viruses; Plants; Polyploidy; Quinolines; Rats; Ultraviolet Rays; Xeroderma Pigmentosum; Yeasts | 1976 |
Broad-spectrum anti-DNA virus and anti-retrovirus activity of phosphonylmethoxyalkylpurines and -pyrimidines.
Topics: Adenine; Animals; Antiviral Agents; Cidofovir; Cytosine; DNA Viruses; DNA, Viral; Guanine; Humans; Organophosphonates; Organophosphorus Compounds; Retroviridae; Virus Replication | 1991 |
Purine salvage pathways in myocardium.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine; Adenosine Kinase; Adenosine Monophosphate; Animals; Guanine; Guanosine; Guanosine Monophosphate; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Inosine Monophosphate; Myocardium; Purine Nucleosides; Purine Nucleotides | 1985 |
The role of the membrane in the utilization of nucleic acid precursors.
Topics: Adenine; Adenosine; Bacillus subtilis; Biological Transport; Cell Membrane; Chromatography, Gel; Cytosine; DNA; Escherichia coli; Guanine; Guanosine; Hydrogen-Ion Concentration; Hypoxanthines; Inosine; Kinetics; Pentosephosphates; Pentosyltransferases; Phosphoric Acids; Purines; Pyrimidines; RNA; Thymine; Uracil; Xanthines | 1974 |
High-performance ion-exchange chromatography with narrow-bore columns: rapid analysis of nucleic acid constituents at the subnanomole level.
Topics: Adenine; Chromatography, Ion Exchange; Cytosine; Evaluation Studies as Topic; Glucose; Guanine; Hexokinase; Ion Exchange Resins; Mathematics; Methods; Microchemistry; Microscopy, Electron, Scanning; Phosphorus Radioisotopes; Ribonucleosides; Ribonucleotides; Spectrophotometry, Ultraviolet; Temperature; Time Factors; Uracil | 1973 |
Radiation damage and repair phenomena.
Topics: Adenine; Animals; Cell Line; Chromosome Aberrations; Cobalt Radioisotopes; Cytosine; DNA; DNA Repair; DNA Replication; Dose-Response Relationship, Radiation; Escherichia coli; Guanine; Humans; Radiation Dosage; Radiation Genetics; Radiation Injuries; Thymine | 1973 |
Genetic aspects of gout.
Topics: Adenine; Allopurinol; Carbon Radioisotopes; Erythrocytes; Fibroblasts; Glucosephosphate Dehydrogenase; Glutamine; Glutathione Reductase; Gout; Guanine; Humans; Hypoxanthines; Lesch-Nyhan Syndrome; Liver; Metabolic Diseases; Molecular Weight; Orotic Acid; Pentosyltransferases; Purines; Uric Acid; Xanthine Oxidase | 1974 |
New paths in the molecular orbital approach to solvation of biological molecules.
Topics: Acetamides; Adenine; Cresols; Cytosine; Dipeptides; Ethanol; Ethanolamines; Ethylamines; Formamides; Formates; Guanine; Histamine; Molecular Conformation; Peptides; Phenethylamines; Proteins; Quantum Theory; Quaternary Ammonium Compounds; Serotonin; Solutions; Solvents; Thymine; Water | 1974 |
[Gas chromatography of nucleic acid components].
Topics: Adenine; Chromatography, Gas; Cytosine; DNA; Guanine; Methods; Nucleic Acids; Nucleotides; Purines; Pyrimidines; RNA; Thymine; Uracil | 1968 |
The molecular basis of embryonic development.
Topics: Adenine; Amino Acid Sequence; Animals; DNA; Embryology; Enzymes; Genetic Code; Glucose; Guanine; Humans; Isoenzymes; L-Lactate Dehydrogenase; Mice; Protein Biosynthesis; Ribosomes; RNA, Messenger; RNA, Transfer; Thymine; Uracil | 1969 |
An introduction to some concepts of molecular biology.
Topics: Adenine; Amino Acid Sequence; Bacteriophages; Cell Differentiation; Cytosine; DNA; DNA Nucleotidyltransferases; Embryonic and Fetal Development; Enzyme Induction; Enzyme Repression; Escherichia coli; Galactosidases; Genetic Code; Guanine; RNA; RNA Nucleotidyltransferases; RNA, Messenger; Thymine; Uracil; Viruses | 1969 |
[Chemical and physical changes produced in DNA by action of ionizing radiation in vitro].
Topics: Adenine; Chemical Phenomena; Chemistry; DNA; Free Radicals; Guanine; Nucleic Acid Denaturation; Peroxides; Purines; Pyrimidines; Radiation Effects | 1969 |
Rickettsiae (as organisms).
Topics: Adenine; Adenosine Triphosphate; Bacteriological Techniques; Cell Division; Citrulline; Cytosine; DNA Replication; DNA, Bacterial; Genetics, Microbial; Guanine; Nucleotides; Rickettsia; Serine; Thymine | 1969 |
The evolution of base sequences in polynucleotides.
Topics: Adenine; Biological Evolution; Cytosine; DNA; DNA, Bacterial; DNA, Viral; Guanine; Molecular Biology; Polynucleotides; RNA; Thymine | 1965 |
Inhibition of animal and invertebrate cell growth by naturally occurring purine bases and ribonucleosides.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Biotransformation; Cattle; Cell Division; Chromosomes; Cricetinae; Cyclic AMP; Deoxyribonucleotides; Guanine; Guanosine; Humans; Invertebrates; Mice; Mitosis; Purine Nucleosides; Purines; Pyrimidines; Rats; RNA; S-Adenosylhomocysteine; Uridine | 1980 |
E. coli RNA polymerase interacts homologously with two different promoters.
Topics: Adenine; Base Sequence; DNA-Directed RNA Polymerases; DNA, Bacterial; DNA, Viral; Escherichia coli; Exonucleases; Guanine; Models, Structural; Operon; Phosphates; T-Phages; Thymine | 1980 |
Nucleoside analogues as antiviral agents.
Topics: Acyclovir; Adenine; Animals; Antiviral Agents; Arabinonucleosides; Bromodeoxyuridine; Chemical Phenomena; Chemistry; Cytarabine; Deoxyuridine; Guanine; Herpesviridae Infections; Humans; Idoxuridine; Nucleosides; Ribavirin; Thymidine; Virus Diseases; Viruses | 1981 |
Enzymes involved in the repair of damaged DNA.
Topics: Adenine; Animals; Base Composition; Chemical Phenomena; Chemistry; Deoxyribonuclease IV (Phage T4-Induced); Deoxyribonucleases; Deoxyribonucleotides; DNA; DNA Glycosylases; DNA Replication; DNA Transposable Elements; DNA-(Apurinic or Apyrimidinic Site) Lyase; DNA-Directed DNA Polymerase; Endonucleases; Escherichia coli; Escherichia coli Proteins; Exonucleases; Guanine; Humans; Methylation; Mutation; N-Glycosyl Hydrolases; Pyrimidine Dimers; Ribonucleotide Reductases; Substrate Specificity; Transcription, Genetic; Ultraviolet Rays; Uracil-DNA Glycosidase | 1981 |
Enhanced repair of O6-alkylguanine in mammalian tissues.
Topics: 2-Acetylaminofluorene; Adenine; Aflatoxin B1; Aflatoxins; Alkylating Agents; Alkylation; Animals; Carcinogens; Cricetinae; Dimethylnitrosamine; DNA; DNA Repair; Dose-Response Relationship, Drug; Gerbillinae; Guanine; Hepatectomy; Liver; Methylnitrosourea; Mice; Rats; Rodentia; Species Specificity | 1984 |
Metabolism of 4-nitroquinoline 1-oxide and related compounds.
Topics: 4-Nitroquinoline-1-oxide; Adenine; Amino Acyl-tRNA Synthetases; Animals; Binding Sites; Biotransformation; Carcinogens; Chemical Phenomena; Chemistry; DNA; Enzyme Activation; Guanine; Nitroquinolines; Nucleic Acids; Oxidation-Reduction | 1981 |
[Oxidative reactions of the base moiety in purine nucleosides and their applications].
Topics: Adenine; Adenosine; Cyclic N-Oxides; Guanine; Oxidation-Reduction | 1995 |
Mechanisms of formation of 1,N6-ethenoadenine, 3,N4-ethenocytosine, 1,N2-ethenoguanine and N2,3-ethenoguanine DNA adducts from substituted oxiranes.
Topics: Adenine; Cytosine; DNA Adducts; Ethylene Oxide; Guanine; Guanosine; Mutagens | 1994 |
[DNA oxidative damages--free radical modification of bases and sugar moieties].
Topics: Adenine; Anaerobiosis; Carbohydrate Metabolism; Cytosine; DNA; Free Radicals; Guanine; Hydroxyl Radical; Mutagenesis; Oxidation-Reduction; Purines; Pyrimidines | 1997 |
Molecular dynamic simulations of environment and sequence dependent DNA conformations: the development of the BMS nucleic acid force field and comparison with experimental results.
Topics: Adenine; Computer Simulation; Crystallography, X-Ray; Cytosine; Deoxyribose; DNA; Guanine; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Conformation; Oligonucleotides; Organophosphates; Thymine | 1998 |
Facts about the artifacts in the measurement of oxidative DNA base damage by gas chromatography-mass spectrometry.
Topics: Adenine; Animals; Artifacts; Base Pairing; Cattle; Cytosine; DNA; DNA Damage; DNA Repair; Gas Chromatography-Mass Spectrometry; Guanine; Humans; Oxidation-Reduction; Oxidative Stress; Pentoxyl; Pyrimidines; Temperature; Thymus Gland | 1998 |
Molecular precursor lesions in oesophageal cancer.
Topics: Adenine; Adenocarcinoma; Base Pairing; Carcinoma, Squamous Cell; Clone Cells; Disease Progression; Esophageal Neoplasms; Genes, p53; Guanine; Humans; Mutation; Precancerous Conditions; Survival Rate; Thymine | 1998 |
Structural studies of atom-specific anticancer drugs acting on DNA.
Topics: Adenine; Antibiotics, Antineoplastic; Anticarcinogenic Agents; Binding Sites; DNA; Guanine; Intercalating Agents; Structure-Activity Relationship | 1999 |
[Autosomal dominant spinocerebellar ataxia].
Topics: Adenine; Cell Death; Cytosine; Genes, Dominant; Guanine; Humans; Inclusion Bodies; Peptides; Point Mutation; Repetitive Sequences, Nucleic Acid; Spinocerebellar Degenerations | 1999 |
Review and management of patients with the prothrombin G20210A polymorphism.
Topics: 3' Untranslated Regions; Adenine; Brain Ischemia; Coronary Disease; Guanine; Humans; Ischemic Attack, Transient; Point Mutation; Polymorphism, Genetic; Prothrombin; Thromboembolism; Venous Thrombosis | 2000 |
G to A 20210 prothrombin polymorphism and venous thrombosis: simple association or causal relationship?
Topics: Adenine; Blood Coagulation; Guanine; Humans; Point Mutation; Polymorphism, Genetic; Prothrombin; Venous Thrombosis | 2000 |
Therapeutic developments in cytomegalovirus retinitis.
Topics: Adenine; Antibodies, Monoclonal; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drugs, Investigational; Foscarnet; Ganciclovir; Guanine; Humans; Organophosphonates; Organophosphorus Compounds; Thionucleotides; Valganciclovir | 2000 |
Involvement of astrocytes in purine-mediated reparative processes in the brain.
Topics: Adenine; Adenosine Triphosphate; Animals; Astrocytes; Brain; Brain Diseases; Brain Injuries; Cell Division; Chickens; Energy Metabolism; Extracellular Space; Guanine; Guanosine Triphosphate; Humans; Ion Transport; Mice; Nerve Growth Factors; Nerve Tissue Proteins; Neuroprotective Agents; Nucleosides; Nucleotides; Rats; Receptors, Purinergic P1; Receptors, Purinergic P2; Signal Transduction; Transforming Growth Factor beta | 2001 |
[From gene to disease; mutation in mitochondrial DNA and maternally inherited diabetes mellitus with deafness (MIDD)].
Topics: Adenine; Adult; Deafness; Diabetes Complications; Diabetes Mellitus; DNA, Mitochondrial; Female; Guanine; Hearing Loss, High-Frequency; Humans; Insulin; Insulin Secretion; Male; Mutation; Netherlands; Pancreas; Prevalence; RNA, Transfer | 2001 |
Base excision repair in nuclear and mitochondrial DNA.
Topics: Adenine; Aging; Animals; Base Sequence; Cell Line; Cell Nucleus; Cell-Free System; DNA; DNA Damage; DNA Glycosylases; DNA Polymerase beta; DNA Repair; DNA-Formamidopyrimidine Glycosylase; DNA, Mitochondrial; Guanine; Hypoxanthine; Lymphocytes; Mammals; Mice; Mitochondria; Molecular Sequence Data; N-Glycosyl Hydrolases; Oxidants; Oxidation-Reduction; Oxidative Stress; Point Mutation; Proliferating Cell Nuclear Antigen; Rats; Thymine | 2001 |
Potential double-flipping mechanism by E. coli MutY.
Topics: Adenine; Amino Acid Sequence; Bacterial Proteins; Base Pair Mismatch; Carbon-Oxygen Lyases; Catalysis; Catalytic Domain; Deoxyribonuclease IV (Phage T4-Induced); DNA Damage; DNA Glycosylases; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Guanine; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; N-Glycosyl Hydrolases; Phosphoric Monoester Hydrolases; Protein Conformation; Protein Structure, Tertiary; Pyrophosphatases; Sequence Alignment; Sequence Homology, Amino Acid; Structure-Activity Relationship; Substrate Specificity | 2001 |
Nucleoside analogues for chronic hepatitis B.
Topics: 2-Aminopurine; Adenine; Antiviral Agents; Famciclovir; Ganciclovir; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Organophosphonates; Reverse Transcriptase Inhibitors | 2001 |
[New management strategies for hepatitis B].
Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Deoxycytidine; Emtricitabine; Guanine; Hepatitis B; Humans; Lamivudine; Organophosphonates | 2002 |
Long-distance electron transfer through DNA.
Topics: Adenine; Base Pair Mismatch; Dimerization; DNA; DNA-Binding Proteins; Electron Transport; Flavins; Gamma Rays; Guanine; Molecular Structure; Nucleic Acid Conformation; Oxidative Stress | 2002 |
Molecular biology of the androgen receptor.
Topics: Adenine; Animals; Cytosine; Guanine; Humans; Male; Prostatic Neoplasms; Receptors, Androgen; Risk; Transcription, Genetic; Trinucleotide Repeats | 2002 |
Prevention of recurrent hepatitis B post-liver transplantation.
Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B; Humans; Immunoglobulins; Lamivudine; Liver Transplantation; Organophosphonates; Postoperative Complications; Reverse Transcriptase Inhibitors; Secondary Prevention; Viral Hepatitis Vaccines | 2002 |
Electron transfer in DNA.
Topics: Adenine; Base Sequence; DNA; DNA-Binding Proteins; Electron Transport; Guanine; Kinetics; Nucleic Acid Conformation; Oxidation-Reduction; Static Electricity; Thermodynamics | 2002 |
Prevention of and treatment for hepatitis B virus infection after liver transplantation in the nucleoside analogues era.
Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B; Hepatitis B virus; Humans; Lamivudine; Liver Transplantation; Nucleosides; Organophosphonates; Postoperative Complications; Recurrence; Time Factors; Transplantation Immunology | 2003 |
[Antiviral therapy for chronic viral hepatitis B and C].
Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B, Chronic; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Interferon-beta; Lamivudine; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Treatment Outcome | 2003 |
ENZYMATIC ALTERATION OF NUCLEIC ACID STRUCTURE.
Topics: Adenine; Biochemical Phenomena; Biochemistry; Carbon Isotopes; Cytosine; DNA; DNA, Bacterial; Enzymes; Escherichia coli; Guanine; Metabolism; Methionine; Phosphorus Isotopes; Proteins; Research; RNA; RNA, Messenger; Species Specificity; Thymine; Tritium | 1964 |
ALKYLATING AGENTS.
Topics: Adenine; Alkylating Agents; Carcinogens; Chemical Phenomena; Chemistry; Cytosine; DNA; Ethers; Ethers, Cyclic; Guanine; Humans; Imines; Lactones; Mechlorethamine; Methane; Mutation; Nucleic Acids; Research; Thymine | 1964 |
Enzymology of repair of etheno-adducts.
Topics: Adenine; Animals; Cytosine; DNA Adducts; DNA Damage; DNA Glycosylases; DNA Repair; Guanine; Humans; Lipid Peroxidation; Reactive Oxygen Species; Thymine DNA Glycosylase | 2003 |
Doctor to patient transmission of hepatitis B virus: implications of HBV DNA levels and potential new solutions.
Topics: Adenine; Antiviral Agents; DNA, Viral; Guanine; Hepatitis B; Hepatitis B e Antigens; Hepatitis B virus; Humans; Infectious Disease Transmission, Professional-to-Patient; Interferon-alpha; Lamivudine; Organophosphonates; Organophosphorus Compounds; Physicians; Risk Factors; Risk Management; Tenofovir; Viral Load | 2003 |
Treatment of HBeAg negative chronic hepatitis B with new drugs (adefovir and others).
Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Deoxycytidine; Emtricitabine; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Nucleosides; Organophosphonates | 2003 |
Editorial comment: HIV and HBV coinfection--a coming-of-age in treatment strategies.
Topics: Adenine; Antiviral Agents; Comorbidity; Deoxycytidine; Drug Resistance, Viral; Emtricitabine; Guanine; Hepatitis B, Chronic; HIV Infections; Humans; Lamivudine; Organophosphonates; Organophosphorus Compounds; Tenofovir | 2004 |
[New approaches in the treatment of hepatitis B].
Topics: 2-Aminopurine; Adenine; Antiviral Agents; Arabinofuranosyluracil; Carcinoma, Hepatocellular; Contraindications; Deoxycytidine; Emtricitabine; Famciclovir; Guanine; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Liver Neoplasms; Organophosphonates; Organophosphorus Compounds; Polyethylene Glycols; Prodrugs; Prognosis; Recombinant Proteins; Tenofovir; Zalcitabine | 2004 |
Molecular virology of hepatitis B virus.
Topics: Adenine; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Genotype; Guanine; Hepatitis B; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Lamivudine; Mutation; Organophosphonates; Reverse Transcriptase Inhibitors; Transcription, Genetic; Viral Proteins; Virus Replication | 2004 |
New treatment of chronic hepatitis B.
Topics: Adenine; Animals; Antiviral Agents; Arabinofuranosyluracil; Deoxycytidine; Drug Resistance, Viral; Emtricitabine; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Organophosphorus Compounds; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Treatment Outcome | 2004 |
Nucleobases as supramolecular motifs.
Topics: Adenine; Cytosine; DNA; Guanine; Nucleic Acid Conformation; Purines; Pyrimidines; RNA; Thymine; Uracil; Zinc; Zinc Fingers | 2005 |
Riboswitch structures: purine ligands replace tertiary contacts.
Topics: Adenine; Base Pairing; Crystallography, X-Ray; Guanine; Hypoxanthine; Ligands; Nucleic Acid Conformation; Purines; Regulatory Sequences, Ribonucleic Acid; RNA | 2005 |
Drugs in development for hepatitis B.
Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Deoxycytidine; Emtricitabine; Guanine; Hepatitis B; Humans; Interferon alpha-2; Interferon-alpha; Nucleosides; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Tenofovir | 2005 |
[Aggregation and toxicity of the proteins with polyQ repeats].
Topics: Adenine; Apoptosis; Cytosine; Gene Expression Regulation; Guanine; Humans; Molecular Chaperones; Mutation; Neurodegenerative Diseases; Peptides; Repetitive Sequences, Amino Acid; Transglutaminases; Trinucleotide Repeat Expansion | 2005 |
Measuring DNA nucleobase adducts using neutral hydrolysis and liquid chromatography-mass spectrometry.
Topics: Adenine; Animals; Chromatography, Liquid; DNA; DNA Adducts; Forecasting; Guanine; Humans; Hydrolysis; Mass Spectrometry | 2005 |
[Treatment of chronic hepatitis B].
Topics: Adenine; Administration, Oral; Antiviral Agents; Biopsy; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Drug Tolerance; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Interferons; Lamivudine; Liver; Mutation; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Reverse Transcriptase Inhibitors; Time Factors; Virus Replication | 2006 |
[Liver transplantation for complications of hepatitis B].
Topics: Adenine; Antiviral Agents; Clinical Trials as Topic; Drug Resistance, Viral; Drug Therapy, Combination; Follow-Up Studies; Guanine; Hepatitis B Vaccines; Hepatitis B virus; Hepatitis B, Chronic; Humans; Immunoglobulins; Lamivudine; Liver Cirrhosis; Liver Transplantation; Mutation; Organophosphonates; Recurrence; Reverse Transcriptase Inhibitors; Tenofovir; Time Factors; Vaccination; Viral Load; Virus Replication | 2006 |
Hoogsteen base-pairing revisited: resolving a role in normal biological processes and human diseases.
Topics: Adenine; Base Pairing; DNA; DNA Replication; G-Quadruplexes; Gene Expression Regulation; Genetic Diseases, Inborn; Guanine; Humans; Recombination, Genetic; Thymidine | 2006 |
Medical therapy of patients affected by HBeAg-negative chronic hepatitis B.
Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Organophosphonates; Polyethylene Glycols; Recombinant Proteins | 2006 |
Personal view: the management of chronic hepatitis B infection.
Topics: Adenine; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interferons; Lamivudine; Organophosphonates; Tenofovir | 2006 |
Prevention and treatment of recurrent Hepatitis B after liver transplantation: the current role of nucleoside and nucleotide analogues.
Topics: Adenine; Antiviral Agents; Drug Therapy, Combination; Guanine; Hepatitis B; Humans; Immunoglobulins; Lamivudine; Liver Transplantation; Nucleosides; Nucleotides; Organophosphonates; Recurrence; Tenofovir | 2006 |
Hepatitis B: the pathway to recovery through treatment.
Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Guanine; Hepatitis B; Hepatitis C, Chronic; Humans; Interferon-alpha; Lamivudine; Organophosphonates; Reverse Transcriptase Inhibitors | 2006 |
New developments in the treatment of chronic hepatitis B.
Topics: Adenine; Animals; Antiviral Agents; Clinical Trials as Topic; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Organophosphonates; Patient Selection; Polyethylene Glycols; Recombinant Proteins | 2006 |
Antiretroviral therapy for hepatitis B virus-HIV-coinfected patients: promises and pitfalls.
Topics: Adenine; Antiretroviral Therapy, Highly Active; Antiviral Agents; Deoxycytidine; Drug Combinations; Emtricitabine; Guanine; Hepatitis B; Hepatitis B virus; HIV Infections; HIV-1; Humans; Lamivudine; Organophosphonates; Preventive Medicine; Tenofovir | 2006 |
[Therapy of hepatitis B virus infection].
Topics: Adenine; Antiviral Agents; Drug Antagonism; Drug Resistance, Viral; Drug Synergism; Drug Therapy, Combination; Forecasting; Guanine; Hepatitis B; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Immunosuppressive Agents; Interferon alpha-2; Interferon-alpha; Lamivudine; Liver Cirrhosis; Organophosphonates; Polyethylene Glycols; Prognosis; Recombinant Proteins; Reverse Transcriptase Inhibitors; Time Factors | 2006 |
Analysis of association between maternal tumor necrosis factor-alpha promoter polymorphism (-308), tumor necrosis factor concentration, and preterm birth.
Topics: Adenine; Amniotic Fluid; Female; Genetic Predisposition to Disease; Guanine; Humans; Osmolar Concentration; Polymorphism, Single Nucleotide; Pregnancy; Premature Birth; Promoter Regions, Genetic; Tumor Necrosis Factor-alpha | 2006 |
[Treating chronic lamivudine-resistant hepatitis B in HIV co-infected patients].
Topics: Adenine; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Outcome | 2006 |
Cross-study analysis of the relative efficacies of oral antiviral therapies for chronic hepatitis B infection in nucleoside-naive patients.
Topics: Adenine; Administration, Oral; Algorithms; Antiviral Agents; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Randomized Controlled Trials as Topic; Treatment Outcome | 2007 |
Improving outcomes for patients with chronic hepatitis B.
Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Guanine; Hepatitis B Vaccines; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Polyethylene Glycols; Pyrimidinones; Recombinant Proteins; Telbivudine; Thymidine; Treatment Outcome; Viral Load | 2007 |
Angiokeratoma corporis diffusum in human beta-mannosidosis: Report of a new case and a novel mutation.
Topics: Adenine; Adult; Arabs; Base Sequence; beta-Mannosidase; beta-Mannosidosis; Codon, Nonsense; Codon, Terminator; Cytoplasm; Exons; Fabry Disease; Female; Guanine; Humans; Microscopy, Electron; Molecular Sequence Data; Skin; Vacuoles | 2007 |
[Drugs for hepatitis B and C infection].
Topics: Adenine; Antiviral Agents; Drug Therapy, Combination; Guanine; Hepatitis B; Hepatitis B virus; Hepatitis C; Humans; Lamivudine; Mutation; Oligopeptides; Organophosphonates; Proline; Ribavirin; Serine Proteinase Inhibitors | 2007 |
[Mechanisms of drug resistance in hepatitis viruses B and C].
Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Gene Products, pol; Guanine; Hepacivirus; Hepatitis B; Hepatitis B virus; Hepatitis C; Humans; Interferons; Lamivudine; Mutation; Organophosphonates; Ribavirin; Viral Nonstructural Proteins | 2007 |
Treatment paradigms on hepatitis B e antigen-negative chronic hepatitis B patients.
Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Thymidine | 2007 |
Drug resistance in antiviral treatment for infections with hepatitis B and C viruses.
Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Guanine; Hepacivirus; Hepatitis B; Hepatitis B virus; Hepatitis C; Humans; Lamivudine; Organophosphonates | 2007 |
Treatment of chronic hepatitis B in HIV-infected patients in 2007.
Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B, Chronic; HIV Infections; Humans; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine | 2007 |
Chronic hepatitis B with advanced fibrosis or cirrhosis: impact of antiviral therapy.
Topics: Adenine; Antiviral Agents; Disease Progression; DNA, Viral; Drug Resistance, Viral; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Liver Cirrhosis; Organophosphonates | 2007 |
Electronic spectra, excited state structures and interactions of nucleic acid bases and base assemblies: a review.
Topics: Adenine; Base Pairing; Cytosine; DNA; Guanine; Molecular Structure; Nucleic Acid Conformation; Nucleic Acids; Spectrophotometry; Thymine; Uracil | 2007 |
[Indications for antiviral therapy for chronic hepatitis B].
Topics: Adenine; Antiviral Agents; Biomarkers; Carrier State; Consensus Development Conferences as Topic; DNA, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferons; Japan; Lamivudine; Organophosphonates; Societies, Medical | 2007 |
[Therapy for chronic hepatitis B: relationship between HBV genotype and efficacy or resistance of anti-viral therapy].
Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Genotype; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferons; Lamivudine; Organophosphonates | 2007 |
[Attention-getting sexually transmitted diseases: Hepatitis B].
Topics: Adenine; Adenosine; Antiviral Agents; Comorbidity; Drug Therapy, Combination; Genotype; Guanine; Guanosine; Hepatitis B; Hepatitis B virus; HIV Infections; Humans; Lamivudine; Organophosphonates; Reverse Transcriptase Inhibitors; Sexually Transmitted Diseases, Viral | 2007 |
Review article: Success and failure of nucleoside and nucleotide analogues in chronic hepatitis B.
Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Nucleotides; Organophosphonates; Reverse Transcriptase Inhibitors; Risk Factors; Virus Replication | 2007 |
[Pharmacological agents for the treatment of chronic hepatitis B].
Topics: Adenine; Antiviral Agents; Clinical Trials as Topic; Drug Therapy, Combination; Follow-Up Studies; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Polyethylene Glycols; Pyrimidinones; Recombinant Proteins; Reverse Transcriptase Inhibitors; Telbivudine; Thymidine; Time Factors; Treatment Outcome | 2008 |
Evaluating anti-viral drug selection and treatment duration in HBeAg-negative chronic hepatitis B: a cost-effectiveness analysis.
Topics: Adenine; Antiviral Agents; Cost-Benefit Analysis; Epidemiologic Methods; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Organophosphonates | 2008 |
Review article: current antiviral therapy of chronic hepatitis B.
Topics: Adenine; Antiviral Agents; Carcinoma, Hepatocellular; Deoxycytidine; Drug Resistance, Viral; Emtricitabine; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Liver Cirrhosis; Nucleosides; Organophosphonates; Polyethylene Glycols; Pyrimidinones; Recombinant Proteins; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine; Virus Replication | 2008 |
[Treatment recommendations of chronic hepatitis B. Did the world escape us?].
Topics: Adenine; Antiviral Agents; Disease Management; Drug Therapy, Combination; Guanine; Health Planning Guidelines; Health Services Accessibility; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; National Health Programs; Organophosphonates; Poland; Polyethylene Glycols; Randomized Controlled Trials as Topic; Recombinant Proteins; Treatment Outcome | 2008 |
Treatment of chronic hepatitis B infection: an update of Swedish recommendations.
Topics: Adenine; Antiviral Agents; Carcinoma, Hepatocellular; Deoxycytidine; Drug Therapy, Combination; Emtricitabine; Guanine; Hepatitis B, Chronic; HIV Infections; Humans; Immunocompromised Host; Interferon alpha-2; Interferon-alpha; Lamivudine; Liver Cirrhosis; Liver Transplantation; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Sweden; Tenofovir | 2008 |
[Management of chronic hepatitis B in treatment-naive patients].
Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Guanine; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Korea; Lamivudine; Organophosphonates; Polyethylene Glycols; Practice Guidelines as Topic; Recombinant Proteins | 2008 |
[Management of antiviral-resistant chronic hepatitis B virus infection].
Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Drug Resistance, Multiple, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Mutation; Nucleosides; Organophosphonates; Practice Guidelines as Topic; Pyrimidinones; Telbivudine; Thymidine; Treatment Outcome | 2008 |
Cytokine gene polymorphisms in periodontal disease: a meta-analysis of 53 studies including 4178 cases and 4590 controls.
Topics: Adenine; Alleles; Chronic Periodontitis; Cytosine; Genotype; Guanine; Humans; Interleukin-1alpha; Interleukin-1beta; Interleukin-6; Interleukins; Periodontitis; Polymorphism, Genetic; Thymine; Tumor Necrosis Factor-alpha | 2008 |
LB80380: a promising new drug for the treatment of chronic hepatitis B.
Topics: Adenine; Alanine Transaminase; Antiviral Agents; DNA, Viral; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Immunologic Factors; Organophosphonates; Practice Guidelines as Topic | 2008 |
Hepatitis B and liver transplantation: 2008 update.
Topics: Adenine; Antiviral Agents; Drug Therapy, Combination; Guanine; Hepatitis B; Hepatitis B Vaccines; Humans; Immunoglobulins; Lamivudine; Liver Transplantation; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine | 2009 |
A treatment algorithm for the management of chronic hepatitis B virus infection in the United States: 2008 update.
Topics: Adenine; Antiviral Agents; Case Management; DNA, Viral; Guanine; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Tenofovir; Treatment Outcome; United States | 2008 |
[Acyclic nucleoside phosphonates as potential antineoplastic agents].
Topics: Adenine; Alanine; Animals; Antineoplastic Agents; Cell Line, Tumor; Guanine; Humans; Lymphoma, Non-Hodgkin; Nucleosides; Organophosphonates; Organophosphorus Compounds; Purines | 2008 |
[Interferon in hepatitis B].
Topics: Adenine; Antiviral Agents; Clinical Trials as Topic; Drug Therapy, Combination; Genotype; Guanine; Hepatitis B; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Multicenter Studies as Topic; Nucleosides; Organophosphonates; Polyethylene Glycols; Pyrimidinones; Randomized Controlled Trials as Topic; Recombinant Proteins; Telbivudine; Thymidine; Treatment Outcome | 2008 |
[Nucleoside and nucleotide analogs in the treatment of chronic hepatitis B].
Topics: Adenine; Antiviral Agents; Clinical Trials as Topic; Deoxycytidine; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine; Genotype; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Multicenter Studies as Topic; Nucleosides; Organophosphonates; Pyrimidinones; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine; Treatment Outcome; Virus Replication | 2008 |
[Entecavir].
Topics: Adenine; Anti-HIV Agents; Antiviral Agents; Clinical Trials as Topic; Drug Resistance, Viral; Drug Therapy, Combination; Genotype; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; HIV Infections; Humans; Lamivudine; Liver Cirrhosis; Liver Transplantation; Multicenter Studies as Topic; Organophosphonates; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Treatment Outcome; Viral Load; Virus Replication | 2008 |
[Resistance in hepatitis B virus].
Topics: Adenine; Antiviral Agents; Drug Resistance, Multiple, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Gene Products, pol; Genotype; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Models, Molecular; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Outcome; Virus Replication | 2008 |
[Clinical management of patients with chronic hepatitis B virus infection].
Topics: Adenine; Antiviral Agents; Biopsy; Combined Modality Therapy; Deoxycytidine; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine; Female; Genotype; Guanine; Hepatitis B Antibodies; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Liver; Liver Transplantation; Male; Nucleosides; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine; Virus Replication | 2008 |
[Hepatitis B in patients with HIV infection].
Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Antiviral Agents; Comorbidity; Deoxycytidine; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine; Guanine; Hepatitis B; Hepatitis B Vaccines; Hepatitis B virus; HIV; HIV Infections; Humans; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Practice Guidelines as Topic; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine; Virus Replication | 2008 |
Role of combination therapy in chronic hepatitis B.
Topics: Adenine; Antiviral Agents; Deoxycytidine; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine; Guanine; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferons; Lamivudine; Organophosphonates; Salvage Therapy; Treatment Outcome | 2009 |
Nucleos(t)ide analogues for hepatitis B virus: strategies for long-term success.
Topics: Adenine; Adenine Nucleotides; Alanine Transaminase; Carcinoma, Hepatocellular; DNA, Viral; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver Cirrhosis; Liver Neoplasms; Nucleosides; Organophosphonates; Pyrimidinones; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Telbivudine; Thymidine; Treatment Outcome; Virus Replication | 2008 |
Peginterferon for the treatment of chronic hepatitis B in the era of nucleos(t)ide analogues.
Topics: Adenine; Antiviral Agents; DNA, Viral; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Polyethylene Glycols; Practice Guidelines as Topic; Pyrimidinones; Randomized Controlled Trials as Topic; Recombinant Proteins; Telbivudine; Tenofovir; Thymidine; Treatment Outcome | 2008 |
HBeAg-negative chronic hepatitis B: why do I treat my patients with nucleos(t)ide analogues.
Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Virus Replication | 2009 |
Probing RNA conformational dynamics and heterogeneity using femtosecond time-resolved fluorescence spectroscopy.
Topics: 2-Aminopurine; Adenine; Anisotropy; Equipment Design; Guanine; Models, Molecular; Models, Statistical; Molecular Conformation; Molecular Structure; Nucleic Acid Conformation; RNA; RNA, Viral; Spectrometry, Fluorescence; Time Factors | 2009 |
Post-liver transplant hepatitis B prophylaxis: the role of oral nucleos(t)ide analogues.
Topics: Adenine; Administration, Oral; Antiviral Agents; Drug Administration Schedule; Drug Therapy, Combination; Graft Survival; Guanine; Hepatitis B; Humans; Immunoglobulins; Injections, Intramuscular; Lamivudine; Liver Transplantation; Nucleosides; Nucleotides; Organophosphonates; Secondary Prevention; Tenofovir; Treatment Outcome | 2009 |
[Chronic hepatitis B: current therapy].
Topics: Adenine; Antiviral Agents; Carcinoma, Hepatocellular; Disease Progression; Guanine; Hepatitis B Vaccines; Hepatitis B virus; Hepatitis B, Chronic; Hepatocytes; Humans; Immunotherapy, Active; Interferon alpha-2; Interferon-alpha; Lamivudine; Liver Neoplasms; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Tenofovir; Treatment Outcome | 2008 |
Avoiding and managing lamivudine resistance in chronic hepatitis B: current approaches and potential strategies including pegylated interferon.
Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Tenofovir | 2010 |
Effect of newer oral antiviral agents on future therapy of chronic hepatitis B.
Topics: Adenine; Administration, Oral; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B, Chronic; Humans; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Treatment Outcome | 2010 |
Current therapeutic strategies for recurrent hepatitis B virus infection after liver transplantation.
Topics: Adenine; Antiviral Agents; Asia; Guanine; Hepatitis B; Hepatitis B virus; Humans; Interferons; Lamivudine; Liver Transplantation; Organophosphonates; Recurrence; Reverse Transcriptase Inhibitors; Tenofovir | 2010 |
On-treatment monitoring of chronic hepatitis B virus infection: an Asian-Pacific perspective.
Topics: Adenine; Antiviral Agents; Asia; Biomarkers; DNA, Viral; Drug Monitoring; Drug Resistance, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Time Factors; Treatment Outcome; Viral Load; Virus Replication | 2010 |
Tenofovir and entecavir are the most effective antiviral agents for chronic hepatitis B: a systematic review and Bayesian meta-analyses.
Topics: Adenine; Antiviral Agents; Drug Therapy, Combination; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Organophosphonates; Tenofovir | 2010 |
Mixed treatment comparison meta-analysis evaluating the relative efficacy of nucleos(t)ides for treatment of nucleos(t)ide-naive patients with chronic hepatitis B.
Topics: Adenine; Antiviral Agents; Drug Therapy, Combination; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Nucleotides; Organophosphonates; Tenofovir; Treatment Outcome; Viral Load | 2010 |
Review article: chronic hepatitis B - anti-viral or immunomodulatory therapy?
Topics: Adenine; Antiviral Agents; Decision Making; Guanine; Hepatitis B, Chronic; Humans; Immunomodulation; Interferon alpha-2; Interferon-alpha; Nucleosides; Organophosphonates; Polyethylene Glycols; Randomized Controlled Trials as Topic; Recombinant Proteins; Tenofovir; Treatment Outcome | 2011 |
Chronic hepatitis B: peginterferon or nucleos(t)ide analogues?
Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Tenofovir; Treatment Outcome | 2011 |
Treatment of HBeAg-positive chronic hepatitis B with nucleos(t)ide analogues.
Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Treatment Outcome | 2011 |
Hepatitis B virus resistance to antiviral drugs: where are we going?
Topics: Adenine; Antiviral Agents; Capsid; Clinical Protocols; Drug Resistance, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Virus Internalization; Virus Replication | 2011 |
The impact of human immunodeficiency virus on viral hepatitis.
Topics: Adenine; Antiviral Agents; Deoxycytidine; Disease Progression; Drug Therapy, Combination; Emtricitabine; Guanine; Hepatitis B; Hepatitis C; Hepatitis Viruses; HIV Infections; Humans; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine | 2011 |
[Treatment of patients with lamivudine-resistant chronic hepatitis B].
Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Organophosphonates | 2011 |
Comparison of the 48-week efficacy between entecavir and adefovir in HBeAg-positive nucleos(t)ide-naïve Asian patients with chronic hepatitis B: a meta-analysis.
Topics: Adenine; Antiviral Agents; Asia; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Organophosphonates; Randomized Controlled Trials as Topic | 2011 |
Novel nephrotoxins.
Topics: Adenine; Alcohols; Angiogenesis Inhibitors; Anticonvulsants; Antipsychotic Agents; Dasatinib; Diphosphonates; Glutamates; Guanine; HIV Protease Inhibitors; Humans; Indoles; Kidney Diseases; Organophosphonates; Oxalates; Pamidronate; Pemetrexed; Phenindione; Plants, Toxic; Proton Pump Inhibitors; Pyrimidines; Pyrroles; Selective Serotonin Reuptake Inhibitors; Sunitinib; Tenofovir; Thiazoles; Triazines | 2011 |
[Interferon-based versus direct antiviral therapy in patients with chronic hepatitis B].
Topics: Adenine; Antiviral Agents; DNA, Viral; Drug Therapy, Combination; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Nucleosides; Nucleotides; Organophosphonates; Polyethylene Glycols; Pyrimidinones; Recombinant Proteins; Telbivudine; Tenofovir; Thymidine; Treatment Outcome | 2011 |
[Progress and perspectives in treatment of chronic hepatitis B].
Topics: Adenine; Anti-HIV Agents; Antiviral Agents; Guanine; Hepatitis B, Chronic; Humans; Interferons; Lamivudine; Organophosphonates | 2011 |
Antiviral therapy for hepatitis B infection during pregnancy and breastfeeding.
Topics: Adenine; Antiviral Agents; Breast Feeding; Female; Guanine; Hepatitis B; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Placenta; Pregnancy; Pregnancy Complications, Infectious; Pyrimidinones; Telbivudine; Tenofovir; Thymidine | 2011 |
Lamivudine plus adefovir combination therapy versus entecavir monotherapy for lamivudine-resistant chronic hepatitis B: a systematic review and meta-analysis.
Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Liver Function Tests; Organophosphonates; Salvage Therapy; Time Factors; Treatment Outcome; Viral Load | 2011 |
Antiviral drugs for viruses other than human immunodeficiency virus.
Topics: Acyclovir; Adenine; Amantadine; Antiviral Agents; Comorbidity; Drug Therapy, Combination; Foscarnet; Ganciclovir; Guanine; Hepatitis; Hepatitis B, Chronic; Hepatitis C; Herpesviridae Infections; HIV Infections; Humans; Influenza, Human; Interferons; Lamivudine; Nucleosides; Oligopeptides; Organophosphonates; Oseltamivir; Proline; Protease Inhibitors; Pyrimidinones; Ribavirin; Telbivudine; Thymidine; Valacyclovir; Valganciclovir; Valine; Virus Replication; Zanamivir | 2011 |
[The past, present and future treatment for chronic hepatitis B].
Topics: Adenine; Adult; Antiviral Agents; Guanine; Hepatitis B, Chronic; Humans; Interferons; Lamivudine; Organophosphonates; Practice Guidelines as Topic | 2011 |
Management of severe acute to fulminant hepatitis B: to treat or not to treat or when to treat?
Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B; Humans; Interferons; Lamivudine; Liver Failure, Acute; Organophosphonates; Tenofovir | 2012 |
[Pharmacological treatment of acute hepatitis B].
Topics: Acute Disease; Adenine; Antiviral Agents; Guanine; Hepatitis B; Humans; Lamivudine; Nucleosides; Organophosphonates; Practice Guidelines as Topic; Pyrimidinones; Spain; Telbivudine; Tenofovir; Thymidine; Treatment Outcome | 2012 |
Quantification of serum hepatitis B surface antigen: is it useful for the management of chronic hepatitis B?
Topics: Adenine; Antiviral Agents; Biomarkers; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Tenofovir; Viral Load | 2012 |
Emerging pipeline drugs for hepatitis B infection.
Topics: Adenine; Antiviral Agents; Clinical Trials as Topic; Drug Design; Drugs, Investigational; Guanine; Hepatitis B Antigens; Hepatitis B Vaccines; Hepatitis B virus; Hepatitis B, Chronic; Humans; Organophosphonates; Tenofovir; Treatment Outcome; Virus Replication | 2011 |
A-6G and A-20C polymorphisms in the angiotensinogen promoter and hypertension risk in Chinese: a meta-analysis.
Topics: Adenine; Angiotensinogen; China; Ethnicity; Genetic Predisposition to Disease; Guanine; Humans; Hypertension; Polymorphism, Genetic; Promoter Regions, Genetic | 2011 |
Meta-analysis: oral anti-viral agents in adults with decompensated hepatitis B virus cirrhosis.
Topics: Adenine; Administration, Oral; Adult; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver Cirrhosis; Nucleosides; Organophosphonates; Pyrimidinones; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine; Time Factors; Treatment Outcome; Viral Load | 2012 |
New advances in chronic hepatitis B.
Topics: Adenine; Antiviral Agents; Coinfection; Disease Progression; Drug Resistance, Viral; Female; Guanine; Guidelines as Topic; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Hepatitis D; HIV Infections; Humans; Interferons; Liver Cirrhosis; Organophosphonates; Pregnancy; Pregnancy Complications, Infectious; Risk Factors; Tenofovir | 2012 |
New perspectives in the therapy of chronic hepatitis B.
Topics: Adenine; Antiviral Agents; Drug Monitoring; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interferons; Interleukins; Organophosphonates; Polymorphism, Genetic; Prognosis; Tenofovir | 2012 |
First-line treatment of chronic hepatitis B with entecavir or tenofovir in 'real-life' settings: from clinical trials to clinical practice.
Topics: Adenine; Antiviral Agents; Clinical Trials as Topic; Guanine; Hepatitis B, Chronic; Humans; Nucleosides; Nucleotides; Organophosphonates; Tenofovir; Treatment Outcome; Viral Load | 2012 |
High genetic barrier nucleos(t)ide analogue(s) for prophylaxis from hepatitis B virus recurrence after liver transplantation: a systematic review.
Topics: Adenine; Antiviral Agents; DNA, Viral; Guanine; Hepatitis B; Hepatitis B virus; Humans; Immunoglobulins; Liver Failure; Liver Transplantation; Nucleotides; Organophosphonates; Recurrence; Tenofovir; Time Factors; Treatment Outcome | 2013 |
Long-term therapy with nucleoside/nucleotide analogues for chronic hepatitis B in Asian patients.
Topics: Adenine; Antiviral Agents; Asian People; Carcinoma, Hepatocellular; Disease Progression; Drug Resistance, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Liver Neoplasms; Organophosphonates; Tenofovir; Treatment Outcome | 2013 |
Considerations for the long-term treatment of chronic hepatitis B with nucleos(t)ide analogs.
Topics: Adenine; Age Factors; Antiviral Agents; Comorbidity; DNA, Viral; Drug Resistance, Viral; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Life Style; Organophosphonates; Severity of Illness Index; Telbivudine; Tenofovir; Thymidine; Time Factors | 2012 |
Diagnostic and therapeutic progress of multi-drug resistance with anti-HBV nucleos(t)ide analogues.
Topics: Adenine; Antiviral Agents; Drug Resistance, Multiple; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferons; Lamivudine; Liver Transplantation; Mutation; Nucleosides; Nucleotides; Organophosphonates; Prognosis; Tenofovir; Viral Load | 2012 |
Cost effectiveness of first-line oral antiviral therapies for chronic hepatitis B : a systematic review.
Topics: Adenine; Antiviral Agents; Cost-Benefit Analysis; Guanine; Health Care Costs; Hepatitis B, Chronic; Humans; Models, Economic; Organophosphonates; Reproducibility of Results; Tenofovir | 2013 |
Letter: First-line monotherapies for chronic hepatitis B - indirect comparison between entecavir and tenofovir.
Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B, Chronic; Humans; Organophosphonates; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Outcome | 2013 |
Solid state structures of cadmium complexes with relevance for biological systems.
Topics: Adenine; Amino Acids; Animals; Cadmium; Edetic Acid; Guanine; Humans; Molecular Structure; Vitamin B Complex | 2013 |
Update in the management of chronic hepatitis B.
Topics: Adenine; Antiviral Agents; Drug Monitoring; Guanine; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Interferon Type I; Organophosphonates; Practice Guidelines as Topic; Tenofovir | 2013 |
Meta-analysis: the impact of oral anti-viral agents on the incidence of hepatocellular carcinoma in chronic hepatitis B.
Topics: Adenine; Administration, Oral; Age Factors; Antiviral Agents; Carcinoma, Hepatocellular; Guanine; Hepatitis B, Chronic; Humans; Incidence; Liver Neoplasms; Organophosphonates; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine; Treatment Outcome | 2013 |
Viral hepatitis and HIV: update and management.
Topics: Adenine; Antiretroviral Therapy, Highly Active; Antiviral Agents; Coinfection; Drug Therapy, Combination; Guanine; Hepatitis C; HIV Infections; Humans; Interferon-alpha; Organophosphonates; Polyethylene Glycols; Protease Inhibitors; Recombinant Proteins; Ribavirin; Tenofovir | 2013 |
[Interdisciplinary aspects of and new drugs for chronic hepatitis B].
Topics: Adenine; Antiviral Agents; Comorbidity; Drug Interactions; Drug Therapy, Combination; Female; Gastroenterology; Guanine; Hematology; Hepatitis B, Chronic; Humans; Hungary; Infant, Newborn; Infant, Newborn, Diseases; Infectious Disease Transmission, Vertical; Interdisciplinary Communication; Interferons; Lamivudine; Medical Oncology; Organophosphonates; Pregnancy; Pregnancy Complications, Infectious; Rheumatology; Tenofovir | 2013 |
Long-term results of treatment with nucleoside and nucleotide analogues (entecavir and tenofovir) for chronic hepatitis B.
Topics: Adenine; Alanine Transaminase; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Organophosphonates; Tenofovir; Treatment Outcome; Virus Replication | 2013 |
[Reactivation of chronic hepatitis B].
Topics: Adenine; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Antiviral Agents; Biomarkers; Guanine; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Immunocompromised Host; Immunosuppressive Agents; Inflammation; Lamivudine; Organophosphonates; Rituximab; Tenofovir; Virus Activation | 2013 |
Efficacy of lamivudine combined with adefovir dipivoxil versus entecavir monotherapy in patients with hepatitis B-associated decompensated cirrhosis: A meta-analysis.
Topics: Adenine; Alanine Transaminase; Antiviral Agents; Creatinine; DNA, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Liver Cirrhosis; Male; Middle Aged; Organophosphonates; Randomized Controlled Trials as Topic; Treatment Outcome | 2014 |
Comparison of the efficacy of Lamivudine plus adefovir versus entecavir in the treatment of Lamivudine-resistant chronic hepatitis B: a systematic review and meta-analysis.
Topics: Adenine; Antiviral Agents; Clinical Trials as Topic; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Organophosphonates; Treatment Outcome | 2013 |
Excitation of nucleobases from a computational perspective I: reaction paths.
Topics: Adenine; Base Pairing; Cytosine; Electrons; Energy Transfer; Guanine; Models, Theoretical; Molecular Structure; Photochemical Processes; Quantum Theory; Thymine; Ultraviolet Rays; Uracil | 2015 |
Review article: nucleos(t)ide analogues in patients with chronic hepatitis B virus infection and chronic kidney disease.
Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Renal Insufficiency, Chronic; Telbivudine; Tenofovir; Thymidine | 2014 |
Regression of fibrosis after HBV antiviral therapy. Is cirrhosis reversible?
Topics: Adenine; Administration, Oral; Antiviral Agents; Carcinoma, Hepatocellular; Fibrosis; Guanine; Hepatitis B; Hepatitis B virus; Humans; Lamivudine; Liver Cirrhosis; Liver Neoplasms; Nucleosides; Organophosphonates; Telbivudine; Tenofovir; Thymidine | 2014 |
HBeAg-positive chronic hepatitis B: why do i treat my patients with Nucleos(t)ide analogs?
Topics: Adenine; Age Factors; Antiviral Agents; Biomarkers; Drug Therapy, Combination; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Polyethylene Glycols; Precision Medicine; Recombinant Proteins; Sex Factors; Telbivudine; Tenofovir; Thymidine; Treatment Outcome | 2014 |
HBeAg-negative chronic hepatitis B: why do I treat my patients with nucleos(t)ide analogues?
Topics: Adenine; Age Factors; Antiviral Agents; Biomarkers; Drug Therapy, Combination; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-alpha; Nucleosides; Organophosphonates; Polyethylene Glycols; Precision Medicine; Recombinant Proteins; Sex Factors; Tenofovir; Treatment Outcome | 2014 |
Impact of HBV therapy on the incidence of hepatocellular carcinoma.
Topics: Adenine; Antiviral Agents; Carcinoma, Hepatocellular; Drug Therapy, Combination; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Liver Cirrhosis; Liver Neoplasms; Nucleosides; Organophosphonates; Tenofovir | 2014 |
New therapeutic perspectives in HBV: when to stop NAs.
Topics: Adenine; Algorithms; Antiviral Agents; Biomarkers; DNA, Viral; Drug Therapy, Combination; Guanine; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Telbivudine; Tenofovir; Thymidine | 2014 |
Peginterferon alpha versus other antiviral regimes for Chinese HBeAg-positive chronic hepatitis B patients.
Topics: Adenine; Antiviral Agents; China; Drug Therapy, Combination; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Interferon-alpha; Organophosphonates; Polyethylene Glycols | 2013 |
An update on hepatitis B, D, and E viruses.
Topics: Adenine; Drug Therapy, Combination; Guanine; Hepatitis B, Chronic; Hepatitis D, Chronic; Hepatitis E; Humans; Interferon-alpha; Liver Cirrhosis; Liver Failure; Organophosphonates; Tenofovir; Treatment Outcome | 2014 |
Managing hepatitis B to prevent liver cancer: recent advances.
Topics: Adenine; Antiviral Agents; Carcinoma, Hepatocellular; Guanine; Hepatitis B, Chronic; Humans; Liver Neoplasms; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir | 2014 |
Excited states behavior of nucleobases in solution: insights from computational studies.
Topics: Adenine; Cytosine; Electrons; Energy Transfer; Guanine; Models, Chemical; Models, Molecular; Photochemical Processes; Quantum Theory; Solutions; Solvents; Thymine; Uracil | 2015 |
Efficacy and resistance in de novo combination lamivudine and adefovir dipivoxil therapy versus entecavir monotherapy for the treatment-naive patients with chronic hepatitis B: a meta-analysis.
Topics: Adenine; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver Function Tests; Organophosphonates; Treatment Outcome | 2014 |
Modified nucleobases.
Topics: Adenine; Cytosine; Energy Transfer; Fluorescent Dyes; Guanine; Models, Molecular; Molecular Structure; Photochemical Processes; Thymine; Uracil | 2015 |
Advances in the treatment of hepatitis B virus/hepatitis C virus coinfection.
Topics: Adenine; Antiviral Agents; Coinfection; DNA, Viral; Drug Therapy, Combination; Guanine; Hepacivirus; Hepatitis B; Hepatitis B virus; Hepatitis C; Hepatitis C, Chronic; HIV Infections; Humans; Organophosphonates; Ribavirin; RNA, Viral; Tenofovir; Virus Replication | 2014 |
Management of chronic hepatitis B in children: an unresolved issue.
Topics: Adenine; Antiviral Agents; Carcinoma, Hepatocellular; Carrier State; Child; Databases, Bibliographic; Guanine; Hepatitis B, Chronic; Humans; Immune Tolerance; Incidence; Interferons; Lamivudine; Liver Cirrhosis; Liver Neoplasms; Nucleosides; Organophosphonates; Risk; Tenofovir | 2014 |
Management of chronic hepatitis B infection: current treatment guidelines, challenges, and new developments.
Topics: Adenine; Antiviral Agents; Disease Management; DNA, Viral; Drug Delivery Systems; Drug Resistance, Viral; Genotype; Guanine; Hepatitis B, Chronic; Humans; Interferons; Organophosphonates; Polyethylene Glycols; Practice Guidelines as Topic; Tenofovir; Viral Load | 2014 |
Comparison of efficacy and safety of tenofovir and entecavir in chronic hepatitis B virus infection: a systematic review and meta-analysis.
Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B, Chronic; Humans; Organophosphonates; Safety; Tenofovir | 2014 |
TNF-α gene promoter polymorphisms contribute to periodontitis susceptibility: evidence from 46 studies.
Topics: Adenine; Cytosine; Genetic Predisposition to Disease; Genotype; Guanine; Humans; Periodontitis; Polymorphism, Genetic; Promoter Regions, Genetic; Tumor Necrosis Factor-alpha | 2014 |
Management of patients with overt or resolved hepatitis B virus infection undergoing rituximab therapy.
Topics: Adenine; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Antibodies, Monoclonal, Murine-Derived; Antiviral Agents; Arthritis, Rheumatoid; Autoimmune Diseases; Carrier State; Disease Management; DNA, Viral; Guanine; Hepatitis B; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Lymphoproliferative Disorders; Organophosphonates; Rituximab; Tenofovir; Virus Activation | 2014 |
Molecular diagnosis and treatment of drug-resistant hepatitis B virus.
Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Molecular Diagnostic Techniques; Mutation; Nucleic Acid Hybridization; Organophosphonates; Phenotype; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; RNA-Directed DNA Polymerase; Sequence Analysis, DNA; Tenofovir; Treatment Outcome | 2014 |
Entecavir plus adefovir combination therapy versus lamivudine add-on adefovir for lamivudine-resistant chronic hepatitis B: A meta-analysis.
Topics: Adenine; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Organophosphonates; Treatment Outcome | 2014 |
Treatment of chronic hepatitis B in clinical practice with entecavir or tenofovir.
Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Organophosphonates; Tenofovir; Treatment Outcome | 2014 |
Prevention of hepatitis B virus reinfection in liver transplant recipients.
Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B; Hepatitis B virus; Humans; Immunoglobulins; Liver; Liver Cirrhosis; Liver Transplantation; Organophosphonates; Recurrence; Reverse Transcriptase Inhibitors; Tenofovir; Transplant Recipients; Virus Replication | 2014 |
Photoionization spectroscopy of nucleobases and analogues in the gas phase using synchrotron radiation as excitation light source.
Topics: Adenine; Cytosine; Electrons; Energy Transfer; Guanine; Mass Spectrometry; Models, Theoretical; Molecular Structure; Phase Transition; Photochemical Processes; Photoelectron Spectroscopy; Radiation, Ionizing; Synchrotrons; Thymine; Uracil | 2015 |
Photochemistry of nucleic acid bases and their thio- and aza-analogues in solution.
Topics: Adenine; Aza Compounds; Cytosine; Guanine; Molecular Structure; Photochemical Processes; Solutions; Sulfur Compounds; Thymine; Ultraviolet Rays; Uracil | 2015 |
Is a polymorphism in 10q25 associated with non-syndromic cleft lip with or without cleft palate? A meta-analysis based on limited evidence.
Topics: Adenine; Chromosomes, Human, Pair 10; Cleft Lip; Cleft Palate; Genetic Predisposition to Disease; Genetic Variation; Guanine; Humans; Polymorphism, Genetic; Risk Factors | 2015 |
Excited states in DNA strands investigated by ultrafast laser spectroscopy.
Topics: Adenine; Base Pairing; Cytosine; DNA; DNA, Single-Stranded; Energy Transfer; Guanine; Lasers; Nucleic Acid Conformation; Photochemical Processes; Protons; Spectrum Analysis; Thymine; Time Factors; Ultraviolet Rays; Uracil | 2015 |
UV-excitation from an experimental perspective: frequency resolved.
Topics: Adenine; Base Pairing; Cytosine; Electrons; Energy Transfer; Guanine; Hydrogen Bonding; Molecular Structure; Photochemical Processes; Spectrum Analysis; Stereoisomerism; Thymine; Ultraviolet Rays; Uracil | 2015 |
Optimal therapy of chronic hepatitis B: how do I treat HBeAg-positive patients?
Topics: Adenine; Antiviral Agents; Drug Therapy, Combination; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interferon-alpha; Long-Term Care; Organophosphonates; Tenofovir; Treatment Outcome | 2015 |
Optimal therapy of chronic hepatitis B: how do I treat my HBeAg-negative patients?
Topics: Adenine; Antiviral Agents; Drug Therapy, Combination; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interferon-alpha; Long-Term Care; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Tenofovir; Treatment Outcome; Virus Replication | 2015 |
Monotherapy for hepatitis B infection: a review of treatment options.
Topics: Adenine; Animals; Antiviral Agents; Carcinoma, Hepatocellular; Guanine; Hepatitis B, Chronic; Humans; Interferons; Lamivudine; Liver Neoplasms; Organophosphonates; Telbivudine; Thymidine; Treatment Outcome | 2015 |
Systematic review with network meta-analysis: Comparative efficacy of oral nucleos(t)ide analogues for the prevention of chemotherapy-induced hepatitis B virus reactivation.
Topics: Adenine; Antineoplastic Agents; Antiviral Agents; Controlled Clinical Trials as Topic; Guanine; Hepatitis B; Hepatitis B virus; Host-Pathogen Interactions; Humans; Lamivudine; Organophosphonates; Telbivudine; Thymidine; Virus Activation | 2016 |
Chronic hepatitis B in children: Therapeutic challenges and perspectives.
Topics: Adenine; Alanine Transaminase; Antigens, Viral; Antiviral Agents; Child; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Immune Tolerance; Interferon-alpha; Lamivudine; Molecular Targeted Therapy; Organophosphonates; Practice Guidelines as Topic; Seroconversion; Telbivudine; Tenofovir; Thymidine; Viral Envelope Proteins | 2017 |
Synthesis of chemically modified DNA.
Topics: Adenine; Cytosine; DNA; DNA Ligases; DNA-Directed DNA Polymerase; Guanine; Oligonucleotides; Polymerase Chain Reaction; Thymine | 2016 |
A Meta-Analysis of the Efficacy of Interferon Monotherapy or Combined with Different Nucleos(t)ide Analogues for Chronic Hepatitis B.
Topics: Adenine; Antiviral Agents; DNA, Viral; Drug Therapy, Combination; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferons; Lamivudine; Odds Ratio; Organophosphonates; Treatment Outcome | 2016 |
Management of Antiviral Resistance in Chronic Hepatitis B.
Topics: Adenine; Antiviral Agents; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; Guanine; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Organophosphonates; Tenofovir | 2017 |
Nucleos(t)ide analogues for preventing HBV reactivation in immunosuppressed patients with hematological malignancies: a network meta-analysis.
Topics: Adenine; Antiviral Agents; Controlled Clinical Trials as Topic; Guanine; Hematologic Neoplasms; Hepatitis B virus; Hepatitis B, Chronic; Humans; Immunocompromised Host; Lamivudine; Organophosphonates; Survival Analysis; Telbivudine; Tenofovir; Thymidine; Treatment Outcome; Virus Activation | 2017 |
Efficacy of Nucleot(s)ide Analogs Therapy in Patients with Unresectable HBV-Related Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis.
Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Carcinoma, Hepatocellular; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver Neoplasms; Organophosphonates; Retrospective Studies; Survival Analysis; Telbivudine; Tenofovir; Thymidine | 2017 |
Site-Specific Self-Catalyzed DNA Depurination: A Biological Mechanism That Leads to Mutations and Creates Sequence Diversity.
Topics: Adenine; beta-Globins; Biological Evolution; Bloom Syndrome; Catalysis; DNA Repair; DNA, Catalytic; DNA, Cruciform; DNA, Single-Stranded; Guanine; Humans; Hydrolysis; Inverted Repeat Sequences; Mutation; Polymorphism, Genetic; Werner Syndrome | 2017 |
Association between MPO-463G > A polymorphism and cancer risk: evidence from 60 case-control studies.
Topics: Adenine; Asian People; Gene Frequency; Genetic Predisposition to Disease; Genotype; Guanine; Humans; Neoplasms; Odds Ratio; Peroxidase; Polymorphism, Single Nucleotide; Prognosis; Risk Factors; White People | 2017 |
Long-term safety and efficacy of nucleo(t)side analogue therapy in hepatitis B.
Topics: Adenine; Administration, Oral; Alanine; Antiviral Agents; Drug-Related Side Effects and Adverse Reactions; Guanine; Hepatitis B, Chronic; Humans; Nucleosides; Randomized Controlled Trials as Topic; Tenofovir; Time Factors; Treatment Outcome | 2018 |
Bayesian Network Meta-Analysis for Assessing Adverse Effects of Anti-hepatitis B Drugs.
Topics: Adenine; Antiviral Agents; Bayes Theorem; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Network Meta-Analysis; Organophosphonates; Prospective Studies; Telbivudine; Tenofovir | 2019 |
New Nucleoside Analogues for the Treatment of Hemorrhagic Fever Virus Infections.
Topics: Adenine; Adenosine; Alanine; Amides; Antiviral Agents; Base Pairing; Ebolavirus; Guanine; Hemorrhagic Fevers, Viral; Humans; Nucleotides; Phosphoric Acids; Pyrazines; Triazines | 2019 |
Polymorphic Cytosine-Adenine-Guanine Repeat Length of Androgen Receptor Gene and Gender Incongruence in Trans Women: A Systematic Review and Meta-Analysis of Case-Control Studies.
Topics: Adenine; Case-Control Studies; Cytosine; Female; Guanine; Humans; Male; Polymorphism, Genetic; Pregnancy; Receptors, Androgen; Signal Transduction; Transgender Persons; Trinucleotide Repeats | 2020 |
Functional Systems Derived from Nucleobase Self-assembly.
Topics: Adenine; Base Pairing; Coordination Complexes; Cytosine; DNA; Electron Transport; Energy Transfer; Guanine; Molecular Conformation; Oxidation-Reduction; Surface Properties; Thymine; Uracil | 2020 |
Combination of Entecavir or Tenofovir with Pegylated Interferon-α for Long-Term Reduction in Hepatitis B Surface Antigen Levels: Simultaneous, Sequential, or Add-on Combination Therapy.
Topics: Adenine; Antiviral Agents; DNA, Viral; Drug Therapy, Combination; Genotype; Guanine; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Interferon-alpha; Lamivudine; Organophosphonates; Randomized Controlled Trials as Topic; Reproducibility of Results; Tenofovir; Treatment Outcome; Viral Load | 2021 |
Purine Metabolism Dysfunctions: Experimental Methods of Detection and Diagnostic Potential.
Topics: Adenine; Animals; Guanine; Humans; Mammals; Purines; Uric Acid; Xanthine Dehydrogenase | 2023 |
60 trial(s) available for adenine and guanine
| Article | Year |
|---|---|
Use of first nucleotide change technology to determine the frequency of factor V Leiden in a population of Australian blood donors.
Topics: Adenine; Australia; Blood Donors; Factor V; Genetic Testing; Genetic Variation; Guanine; Humans; Mutation; Prevalence; Risk Factors; Thrombophilia | 1997 |
New sensitive method for the detection of the A3243G mutation of human mitochondrial deoxyribonucleic acid in diabetes mellitus patients by ligation-mediated polymerase chain reaction.
Topics: Adenine; Adult; Aged; Aged, 80 and over; Cell Line; Diabetes Mellitus; DNA, Mitochondrial; Female; Guanine; Humans; Leukocytes; Male; Middle Aged; Point Mutation; Polymerase Chain Reaction; Sensitivity and Specificity | 1998 |
Oxidative DNA base damage in lymphocytes of HIV-infected drug users.
Topics: Adenine; Adolescent; Adult; Chromatin; Cytosine; DNA Damage; Guanine; HIV Infections; Humans; Lymphocytes; Male; Oxidation-Reduction; Oxidative Stress; Substance Abuse, Intravenous; Uracil | 1999 |
Polymorphisms of the SUR1 (ABCC8) and Kir6.2 (KCNJ11) genes predict the conversion from impaired glucose tolerance to type 2 diabetes. The Finnish Diabetes Prevention Study.
Topics: Adenine; Adult; Alleles; ATP-Binding Cassette Transporters; Confidence Intervals; Diabetes Mellitus, Type 2; Disease Progression; Genetic Predisposition to Disease; Glucose Intolerance; Guanine; Haplotypes; Humans; Linkage Disequilibrium; Lysine; Middle Aged; Odds Ratio; Polymorphism, Genetic; Potassium Channels; Potassium Channels, Inwardly Rectifying; Promoter Regions, Genetic; Receptors, Drug; Sulfonylurea Receptors | 2004 |
Obese subjects carrying the 11482G>A polymorphism at the perilipin locus are resistant to weight loss after dietary energy restriction.
Topics: Adenine; Adult; Aged; Alleles; Caloric Restriction; Carrier Proteins; Diabetes Mellitus, Type 2; Female; Guanine; Heterozygote; Humans; Male; Middle Aged; Obesity; Perilipin-1; Phosphoproteins; Polymorphism, Genetic; Prevalence; Weight Loss | 2005 |
The effect of MDR1 G2677T/A polymorphism on pharmacokinetics of gabapentin in healthy Korean subjects.
Topics: Adenine; Administration, Oral; Adult; Amines; Anticonvulsants; Area Under Curve; Asian People; ATP Binding Cassette Transporter, Subfamily B, Member 1; Capsules; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Exons; Gabapentin; gamma-Aminobutyric Acid; Genotype; Guanine; Half-Life; Humans; Korea; Male; Metabolic Clearance Rate; Phenotype; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Reference Values; Reproducibility of Results; Thymine | 2007 |
Absence of a pharmacokinetic interaction between entecavir and adefovir.
Topics: Adenine; Adolescent; Adult; Antiviral Agents; Area Under Curve; Cross-Over Studies; Drug Interactions; Female; Guanine; Humans; Male; Organophosphonates | 2007 |
Cost effectiveness of entecavir versus lamivudine with adefovir salvage in HBeAg-positive chronic hepatitis B.
Topics: Adenine; Anti-HIV Agents; Antiviral Agents; Cohort Studies; Cost-Benefit Analysis; Disease Progression; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Markov Chains; Organophosphonates; Quality of Life; Salvage Therapy | 2007 |
Early hepatitis B virus DNA reduction in hepatitis B e antigen-positive patients with chronic hepatitis B: A randomized international study of entecavir versus adefovir.
Topics: Adenine; Adolescent; Adult; Alanine Transaminase; Antiviral Agents; DNA, Viral; Female; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Organophosphonates; Viral Load | 2009 |
[A study on the treatment of chronic hepatitis B with YMDD mutation].
Topics: Adenine; Adult; Alanine Transaminase; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Follow-Up Studies; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Reverse Transcriptase Inhibitors; Young Adult | 2009 |
Efficacy of entecavir in patients with chronic hepatitis B resistant to both lamivudine and adefovir or to lamivudine alone.
Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Dose-Response Relationship, Drug; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Multivariate Analysis; Organophosphonates; Treatment Outcome | 2009 |
Rescue monotherapy in lamivudine-resistant hepatitis B e antigen-positive chronic hepatitis B: adefovir versus entecavir.
Topics: Adenine; Adult; Aged; Antiviral Agents; Drug Resistance, Viral; Female; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Retrospective Studies; Reverse Transcriptase Inhibitors; Salvage Therapy; Treatment Outcome; Young Adult | 2009 |
[Comparison of efficacy between adefovir dipivoxil and entecavir in patients with chronic hepatitis B].
Topics: Adenine; Administration, Oral; Alanine Transaminase; Antiviral Agents; DNA, Viral; Female; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Male; Organophosphonates; Polymerase Chain Reaction; Prospective Studies; Treatment Outcome; Virus Replication | 2010 |
Antiviral effect of entecavir in chronic hepatitis B: influence of prior exposure to nucleos(t)ide analogues.
Topics: Adenine; Adult; Antiviral Agents; Drug Resistance, Viral; Female; Follow-Up Studies; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Kaplan-Meier Estimate; Lamivudine; Male; Middle Aged; Organophosphonates; Proportional Hazards Models; Prospective Studies; Reverse Transcriptase Inhibitors; Virus Replication | 2010 |
[Comparison of the efficacy of 48 week-Entecavir therapy with that of Adefovir therapy for chronic hepatitis B patients].
Topics: Adenine; Adolescent; Adult; Antiviral Agents; DNA, Viral; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates; Treatment Outcome; Young Adult | 2010 |
Adenine, guanine and pyridine nucleotides in blood during physical exercise and restitution in healthy subjects.
Topics: Adenine; Adenine Nucleotides; Adult; Erythrocytes; Exercise; Guanine; Guanine Nucleotides; Health; Humans; Male; Purine Nucleotides; Pyridines; Rest; Young Adult | 2010 |
Long-term therapy with tenofovir is effective for patients co-infected with human immunodeficiency virus and hepatitis B virus.
Topics: Adenine; Adult; Anti-HIV Agents; Antiviral Agents; CD4 Lymphocyte Count; DNA, Viral; Drug Resistance, Viral; Female; Follow-Up Studies; Guanine; Hepatitis B virus; Hepatitis B, Chronic; HIV Infections; Humans; Kaplan-Meier Estimate; Kidney; Male; Middle Aged; Organophosphonates; Prospective Studies; Tenofovir; Time Factors; Virus Replication | 2010 |
Efficacy of adefovir add-on lamivudine rescue therapy compared with switching to entecavir monotherapy in patients with lamivudine-resistant chronic hepatitis B.
Topics: Adenine; Adult; Aged; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Treatment Outcome; Young Adult | 2010 |
Tenofovir disoproxil fumarate (TDF), emtricitabine/TDF, and entecavir in patients with decompensated chronic hepatitis B liver disease.
Topics: Adenine; Adolescent; Adult; Aged; Creatinine; Deoxycytidine; DNA, Viral; Drug Combinations; Emtricitabine; Female; Guanine; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates; Tenofovir; Viral Load | 2011 |
Association of intrahepatic cccDNA reduction with the improvement of liver histology in chronic hepatitis B patients receiving oral antiviral agents.
Topics: Adenine; Adult; Antiviral Agents; Blood; DNA, Circular; DNA, Viral; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Histocytochemistry; Humans; Liver; Male; Middle Aged; Organophosphonates; Placebos; Treatment Outcome; Viral Load | 2011 |
Efficacy and safety of entecavir versus adefovir in chronic hepatitis B patients with hepatic decompensation: a randomized, open-label study.
Topics: Adenine; Antiviral Agents; DNA, Viral; Dose-Response Relationship, Drug; Drug Resistance, Viral; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver Failure; Male; Middle Aged; Organophosphonates; Survival Rate; Treatment Outcome | 2011 |
[Safety and efficacy of Entecavir combined with Adefovir in patients with chronic hepatitis B who fail to respond to nucleoside analog treatment].
Topics: Adenine; Adult; Antiviral Agents; Drug Therapy, Combination; Female; Guanine; Hepatitis B, Chronic; Humans; Male; Middle Aged; Nucleosides; Organophosphonates; Treatment Failure | 2011 |
Simple scoring system predicting genotypic resistance during rescue therapy for Lamivudine-resistant chronic hepatitis B.
Topics: Adenine; Adult; Aged; Antiviral Agents; Cohort Studies; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Predictive Value of Tests; Retrospective Studies; Survival Analysis; Treatment Outcome; Young Adult | 2012 |
[Efficacy of two nucleoside analogs to treat resistant HBeAg-negative chronic hepatitis B].
Topics: Adenine; Adolescent; Adult; Antiviral Agents; Child; Child, Preschool; Drug Resistance, Viral; Female; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates; Treatment Outcome; Young Adult | 2011 |
[Clinical antiviral effects of Peg-IFNa-2a in patients with chronic hepatitis B].
Topics: Adenine; Adult; Antiviral Agents; Female; Guanine; Hepatitis B, Chronic; Humans; Interferon-alpha; Male; Middle Aged; Organophosphonates; Treatment Outcome | 2011 |
Treatment response and evolution of HBV resistance during lamivudine plus adefovir or entecavir therapy in patients with adefovir-resistant mutants.
Topics: Adenine; Adult; Aged; Antiviral Agents; Base Sequence; Cloning, Molecular; DNA, Viral; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; Guanine; Hepatitis B; Hepatitis B virus; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates | 2012 |
Randomized trial of entecavir plus adefovir in patients with lamivudine-resistant chronic hepatitis B who show suboptimal response to lamivudine plus adefovir.
Topics: Adenine; Adolescent; Adult; Aged; Antiviral Agents; Drug Resistance, Viral; Female; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Young Adult | 2012 |
[Entecavir 1.0mg monotherapy or entecavir plus adefovir dipivoxil for patients with lamivudine-resistant chronic hepatitis B had suboptimal response to lamivudine plus adefovir dipivoxil].
Topics: Adenine; Adult; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Treatment Outcome | 2011 |
Efficacy of entecavir with or without tenofovir disoproxil fumarate for nucleos(t)ide-naïve patients with chronic hepatitis B.
Topics: Adenine; Adult; Alanine Transaminase; Antiviral Agents; Biomarkers; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Linear Models; Organophosphonates; Phosphorous Acids; Time Factors; Treatment Outcome; Viral Load | 2012 |
Virologic responses to add-on adefovir dipivoxil treatment versus entecavir monotherapy in children with lamivudine-resistant chronic hepatitis B.
Topics: Adenine; Adolescent; Antiviral Agents; Child; Child, Preschool; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Organophosphonates; Treatment Outcome; Viral Load | 2012 |
Rescue therapy for lamivudine-resistant chronic hepatitis B: adefovir monotherapy, adefovir plus lamivudine or entecavir combination therapy.
Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Time Factors | 2012 |
Clonal analysis of the quasispecies of antiviral-resistant HBV genomes in patients with entecavir resistance during rescue treatment and successful treatment of entecavir resistance with tenofovir.
Topics: Adenine; Adult; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genome, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Tenofovir; Treatment Outcome; Young Adult | 2013 |
Comparison of the antiviral effects of entecavir and adefovir dipivoxil in chronic HBV infection: a randomized control trial.
Topics: Adenine; Adult; Aged; Alanine Transaminase; Antiviral Agents; Bilirubin; DNA, Viral; Female; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates; Virus Replication; Young Adult | 2012 |
Adding adefovir vs. switching to entecavir for lamivudine-resistant chronic hepatitis B (ACE study): a 2-year follow-up randomized controlled trial.
Topics: Adenine; Adult; Analysis of Variance; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Female; Follow-Up Studies; Guanine; Hepatitis B; Hepatitis B, Chronic; Humans; Immunoassay; Lamivudine; Male; Middle Aged; Oligonucleotides; Organophosphonates; Prospective Studies; Republic of Korea; Reverse Transcriptase Inhibitors; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Treatment Outcome | 2013 |
Efficacy and safety of telbivudine plus adefovir dipivoxil combination therapy and entecavir monotherapy for HBeAg-positive chronic hepatitis B patients with resistance to adefovir dipivoxil.
Topics: Adenine; Adult; Antiviral Agents; China; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Organophosphonates; Prospective Studies; Telbivudine; Thymidine; Treatment Outcome | 2013 |
Antiviral efficacies of currently available rescue therapies for multidrug-resistant chronic hepatitis B.
Topics: Adenine; Adult; Aged; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Follow-Up Studies; Genotype; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Treatment Outcome | 2013 |
Randomized trial of the virologic response during up to two years of entecavir-adefovir combination therapy in multiple-drug-refractory chronic hepatitis B virus patients.
Topics: Adenine; Adolescent; Adult; Aged; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Treatment Outcome; Viral Load; Young Adult | 2013 |
De novo combined lamivudine and adefovir dipivoxil therapy vs entecavir monotherapy for hepatitis B virus-related decompensated cirrhosis.
Topics: Adenine; Adult; Alanine Transaminase; Analysis of Variance; Antiviral Agents; Biomarkers; Chi-Square Distribution; China; DNA, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B; Hepatitis B e Antigens; Hepatitis B virus; Humans; Lamivudine; Liver Cirrhosis; Male; Middle Aged; Organophosphonates; Prospective Studies; Time Factors; Treatment Outcome | 2013 |
Add-on peg-interferon leads to loss of HBsAg in patients with HBeAg-negative chronic hepatitis and HBV DNA fully suppressed by long-term nucleotide analogs.
Topics: Adenine; Adult; Aged; Antiviral Agents; DNA, Viral; Female; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Interferon-alpha; Male; Middle Aged; Organophosphonates; Polyethylene Glycols; Prospective Studies; Recombinant Proteins | 2013 |
[Therapeutic effect of antiviral regimens for chronic hepatitis B refractory to lamivudine plus adefovir].
Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Mutation; Organophosphonates; Real-Time Polymerase Chain Reaction; Recombinant Proteins | 2013 |
Entecavir 1mg versus combined lamivudine/adefovir dipivoxil in chronic HBV Egyptian patients resistant to LAM monotherapy, non-randomised controlled study.
Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Egypt; Female; Guanine; Hepatitis B Antibodies; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Young Adult | 2014 |
Non-interventional study AI463-12 of real-world chronic HBV infection management--baseline characteristics and treatment patterns of Polish patients kohort.
Topics: Adenine; Adult; Antiviral Agents; Cohort Studies; Europe; Female; Guanine; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Longitudinal Studies; Male; Middle Aged; Organophosphonates; Poland; Practice Guidelines as Topic; Retrospective Studies; Socioeconomic Factors; Treatment Outcome | 2013 |
First-line monotherapies of tenofovir and entecavir have comparable efficacies in hepatitis B treatment.
Topics: Adenine; Adolescent; Adult; Antiviral Agents; Cohort Studies; Drug Resistance, Viral; Female; Follow-Up Studies; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Outcome; Young Adult | 2014 |
Kinetics and prediction of HBsAg loss during long-term therapy with nucleos(t)ide analogues of different potency in patients with chronic hepatitis B.
Topics: Adenine; Adult; Antiviral Agents; Female; Guanine; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates | 2014 |
Tenofovir monotherapy versus tenofovir and entecavir combination therapy in adefovir-resistant chronic hepatitis B patients with multiple drug failure: results of a randomised trial.
Topics: Adenine; Adult; Aged; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates; Republic of Korea; Tenofovir; Treatment Outcome | 2016 |
Delayed Reduction of Hepatitis B Viral Load and Dynamics of Adefovir-Resistant Variants during Adefovir plus Entecavir Combination Rescue Therapy.
Topics: Adenine; Adult; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Mutation; Organophosphonates; Treatment Outcome; Viral Load; Young Adult | 2015 |
Cost-effectiveness analysis of lamivudine, telbivudine, and entecavir in treatment of chronic hepatitis B with adefovir dipivoxil resistance.
Topics: Adenine; Adult; Antiviral Agents; Cost-Benefit Analysis; Double-Blind Method; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Prospective Studies; Telbivudine; Thymidine | 2015 |
[Treatment options in HBeAg-positive chronic hepatitis B patients with a poor response to 24-week interferon monotherapy].
Topics: Adenine; Alanine Transaminase; Antiviral Agents; DNA, Viral; Drug Therapy, Combination; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interferons; Organophosphonates | 2015 |
Hepatitis B Virus Pregenomic RNA Is Present in Virions in Plasma and Is Associated With a Response to Pegylated Interferon Alfa-2a and Nucleos(t)ide Analogues.
Topics: Adenine; Adult; Amantadine; Antiviral Agents; Biomarkers; DNA, Viral; Drug Therapy, Combination; Female; Guanine; Hep G2 Cells; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-alpha; Male; Middle Aged; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Reproducibility of Results; RNA, Viral; Tenofovir; Virion | 2016 |
[A randomized controlled trial on 240-week monotherapy with entecavir or adefovir in patients with chronic hepatitis B and cirrhosis].
Topics: Adenine; Aged; Alanine Transaminase; alpha-Fetoproteins; Antiviral Agents; Aspartate Aminotransferases; Biomarkers; Carcinoma, Hepatocellular; Female; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Organophosphonates; Time Factors | 2015 |
Cost-effectiveness of Lamivudine, Telbivudine, Adefovir Dipivoxil and Entecavir on decompensated hepatitis B virus-related cirrhosis.
Topics: Adenine; Adult; Antiviral Agents; Cost-Benefit Analysis; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver Cirrhosis; Male; Middle Aged; Organophosphonates; Telbivudine; Thymidine; Treatment Outcome | 2016 |
Effect of nucleoside analogues in the treatment of hepatitis B cirrhosis and its effect on Th17 cell.
Topics: Adenine; Adult; Aged; Antiviral Agents; Female; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Liver Cirrhosis; Male; Middle Aged; Organophosphonates; Th17 Cells; Treatment Outcome | 2017 |
Addition of nucleoside analogues to peg-IFNα-2a enhances virological response in chronic hepatitis B patients without early response to peg-IFNα-2a: a randomized controlled trial.
Topics: Adenine; Adult; Antiviral Agents; Drug Therapy, Combination; Female; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interferon-alpha; Liver Cirrhosis; Male; Middle Aged; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Sustained Virologic Response | 2017 |
Effects of the combined administration of entecavir and adefovir dipivoxil to improve hepatic fibrosis in hepatitis B patients with interferon resistance.
Topics: Adenine; Aged; Alanine Transaminase; Antiviral Agents; Aspartate Aminotransferases; Bilirubin; Creatinine; Drug Resistance, Viral; Drug Therapy, Combination; End Stage Liver Disease; Female; Gene Products, pol; Guanine; Hepatitis B, Chronic; Humans; Interferons; Liver Cirrhosis; Male; Middle Aged; Organophosphonates; Reverse Transcriptase Inhibitors; Severity of Illness Index | 2017 |
Phase IV randomized clinical study: Peginterferon alfa-2a with adefovir or entecavir pre-therapy for HBeAg-positive chronic hepatitis B.
Topics: Adenine; Adult; Alanine Transaminase; Antiviral Agents; DNA, Viral; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-alpha; Male; Middle Aged; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Taiwan | 2018 |
Switching from entecavir to tenofovir alafenamide versus maintaining entecavir for chronic hepatitis B.
Topics: Adenine; Adult; Aged; Alanine; Antiviral Agents; Female; Guanine; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Male; Middle Aged; Tenofovir | 2019 |
Mitochondrial toxicity and body shape changes during nucleos(t)ide analogues administration in patients with chronic hepatitis B.
Topics: Adenine; Adiposity; Antiviral Agents; Cross-Sectional Studies; DNA, Mitochondrial; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Middle Aged; Mitochondria; Organophosphonates; RNA, Mitochondrial; Tenofovir | 2020 |
Entecavir+tenofovir vs. lamivudine/telbivudine+adefovir in chronic hepatitis B patients with prior suboptimal response.
Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Prospective Studies; Sustained Virologic Response; Telbivudine; Tenofovir | 2020 |
Short-term and long-term safety and efficacy of tenofovir alafenamide, tenofovir disoproxil fumarate and entecavir treatment of acute-on-chronic liver failure associated with hepatitis B.
Topics: Acute-On-Chronic Liver Failure; Adenine; Adult; Alanine; Antiviral Agents; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Tenofovir; Treatment Outcome | 2021 |
Switching to tenofovir alafenamide versus continued therapy in chronic hepatitis B patients who were treated with entecavir: A prospective, multicenter, randomized controlled study.
Topics: Adenine; Alanine; Antiviral Agents; DNA, Viral; Female; Fumarates; Guanine; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Male; Middle Aged; Prospective Studies; Tenofovir; Treatment Outcome | 2022 |
2906 other study(ies) available for adenine and guanine
| Article | Year |
|---|---|
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
Rational Design of Selective Adenine-Based Scaffolds for Inactivation of Bacterial Histidine Kinases.
Topics: Adenine; Adenosine Triphosphate; Anti-Bacterial Agents; Aspartic Acid; Bacteria; Drug Design; Histidine Kinase; HSP90 Heat-Shock Proteins; Models, Molecular; Molecular Docking Simulation; Structure-Activity Relationship | 2017 |
Protoplasts of Schizosaccharomyces pombe: an improved method for their preparation and the study of their guanine uptake.
Topics: Adenine; Ascomycota; Azaguanine; Azides; Cell Wall; Culture Media; Glycoside Hydrolases; Growth; Guanine; Hydrogen-Ion Concentration; Hypoxanthines; Polysaccharides; Protoplasts; Saccharomyces; Schizosaccharomyces; Snails | 1975 |
Effect of pH and ionic strength on the catalytic and allosteric properties of native and chemically modified ox liver mitochondrial glutamate dehydrogenase.
Topics: Adenine; Adenine Nucleotides; Adenosine; Allosteric Regulation; Allosteric Site; Animals; Cattle; Dinitrophenols; Glutamate Dehydrogenase; Guanine; Guanine Nucleotides; Guanosine; Hydrogen-Ion Concentration; Kinetics; Mitochondria, Liver; Osmolar Concentration; Protein Binding | 1975 |
Determination of trimethylsilyl methylated nucleic acid bases in urine by gas-liquid chromatography.
Topics: Adenine; Adsorption; Chromatography, Gas; Guanine; Humans; Hydrogen-Ion Concentration; Hydrolysis; Methods; Neoplasms; RNA, Transfer; Trimethylsilyl Compounds; tRNA Methyltransferases | 1976 |
High-resolution liquid chromatographic analysis of methylated purine and pyrimidine bases in transfer RNA.
Topics: Adenine; Animals; Cattle; Chemical Phenomena; Chemistry; Chromatography, Liquid; Cytosine; Guanine; Hydrogen-Ion Concentration; Hypoxanthines; Liver; Methylation; Neoplasms; Rats; RNA, Transfer | 1976 |
Adenosine phosphyorylase activity as distinct from inosine-guanosine phosphorylase activity in Sarcoma 180 cells and rat liver.
Topics: Adenine; Adenosine; Animals; Chloromercuribenzoates; Guanine; Hydrogen-Ion Concentration; Inosine; Kinetics; Liver; Pentosyltransferases; Rats; Sarcoma 180 | 1976 |
Chemical methods for the reduction of the purine content of baker's yeast, a form of single-cell protein.
Topics: Adenine; Dietary Proteins; Food; Guanine; Hot Temperature; Hydrogen-Ion Concentration; Osmolar Concentration; Purines; RNA; Saccharomyces cerevisiae | 1976 |
Study of the role of puring phosphoribosyltransferases in the uptake of adenine and guanine by Schizosaccharomyces pombe cells.
Topics: Adenine; Adenine Phosphoribosyltransferase; Ascomycota; Biological Transport; Formycins; Guanine; Hydrogen-Ion Concentration; Hypoxanthine Phosphoribosyltransferase; Kinetics; Pentosyltransferases; Ribose-Phosphate Pyrophosphokinase; Schizosaccharomyces; Species Specificity | 1977 |
Selective reactions of nucleobases under biological conditions.
Topics: Adenine; Chemical Phenomena; Chemistry; Color; Escherichia coli; Guanine; Hydrogen-Ion Concentration; Kinetics; Nitroso Compounds | 1977 |
Kinetics and mechanism of carbon-8 methylation of purine bases and nucleosides by methyl radical.
Topics: Adenine; Adenosine; Caffeine; Guanine; Guanosine; Hot Temperature; Hydrogen-Ion Concentration; Hypoxanthines; Inosine; Kinetics; Methods; Methylation; Photochemistry; Purine Nucleosides | 1977 |
Synthesis and salvage of purines during cellular morphogenesis of Myxococcus xanthus.
Topics: Adenine; Adenosine Triphosphate; Glycine; Guanine; Morphogenesis; Myxococcales; Spores, Bacterial | 1978 |
The methylated purines of Tetrahymena pyriformis transfer ribonucleic acid.
Topics: Adenine; Animals; Chromatography; Guanine; Methylation; Purines; RNA, Transfer; Tetrahymena pyriformis | 1979 |
Purine base transport in Neurospora crassa.
Topics: Adenine; Adenosine; Biological Transport, Active; Cytosine; Guanine; Hypoxanthines; Kinetics; Mutation; Neurospora; Neurospora crassa; Purines; Recombination, Genetic; Spores, Fungal | 1975 |
New class of ribonucleic acid in Neurospora associated with the outer cell envelope.
Topics: Adenine; Cell Membrane; Cytosine; Electrophoresis, Polyacrylamide Gel; Guanine; Methylation; Molecular Weight; Neurospora; Neurospora crassa; Nucleic Acid Denaturation; RNA; Uracil | 1977 |
Theileria parva: purine and pyrimidine metabolism and the action of folate antagonists in parasitized bovine lymphoid cells.
Topics: Adenine; Aminopterin; Animals; Azaguanine; Cattle; Cells, Cultured; Culture Media; Eukaryota; Floxuridine; Folic Acid Antagonists; Guanine; Hypoxanthines; Lymphocytes; Methotrexate; Purines; Pyrimidine Nucleosides; Theileriasis; Thymidine; Uridine | 1977 |
Uptake and efflux of adenine and its derivatives in Neurospora crassa.
Topics: Adenine; Adenosine Triphosphate; Biological Transport, Active; Cell Membrane; Dinitrophenols; Guanine; Hypoxanthines; Kinetics; Neurospora; Neurospora crassa; Xanthines | 1977 |
Mutants of chinese hamster cells resistant to adenosine.
Topics: Adenine; Adenosine; Aminohydrolases; Animals; Carbon Radioisotopes; Cell Count; Cell Division; Cell Line; Cell-Free System; Cricetinae; Drug Resistance; Female; Guanine; Hypoxanthines; Inosine; Inosine Nucleotides; Ketone Oxidoreductases; Mutation; Ovary; Pentosyltransferases; Phosphotransferases; Pyrimidines; Tritium | 1975 |
Involvement of separate pathways in the repair of mutational and lethal lesions induced by a monofunctional sulfur mustard.
Topics: Adenine; Alkylation; Cell Survival; DNA Nucleotidyltransferases; DNA Repair; DNA Replication; DNA, Bacterial; Endonucleases; Escherichia coli; Guanine; Mesylates; Mustard Compounds; Mutagens; Mutation | 1975 |
Purine and pyrimidine transport by cultured Novikoff cells. Specificities and mechanism of transport and relationship to phosphoribosylation.
Topics: Adenine; Animals; Biological Transport, Active; Calorimetry; Carcinoma, Hepatocellular; Cell Line; Centrifugation, Density Gradient; Chloromercuribenzoates; Cytochalasin B; Cytosine; Dipyridamole; Dithiothreitol; Guanine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Kinetics; Liver Neoplasms; Neoplasms, Experimental; Pentosyltransferases; Purines; Pyrimidines; Rats; Thermodynamics; Time Factors; Uracil | 1975 |
Effect of bredinin and its aglycone on L5178Y cells.
Topics: Adenine; Adenosine; Animals; Antibiotics, Antineoplastic; Antifungal Agents; Candida albicans; Cell Line; DNA, Neoplasm; Dose-Response Relationship, Drug; Guanine; Guanine Nucleotides; Guanosine; Guanosine Monophosphate; Imidazoles; Mice; Rats; Ribonucleosides; RNA, Neoplasm | 1975 |
Isolation and identification of products from alkylation of nucleic acids: ethyl- and isopropyl-purines.
Topics: 1-Propanol; Adenine; Alkylation; DNA; Ethanol; Guanine; Mass Spectrometry; Mesylates; Purines | 1975 |
Induction of antiviral activity in vivo and in vitro by human placenta ribonucleic acid treated with nitrous acid.
Topics: Adenine; Animals; Cell Division; Cell Line; Cytosine; Female; Guanine; Humans; Hypoxanthines; Interferons; Mice; Nitrites; Nitrous Acid; Placenta; Pregnancy; Rabbits; RNA; Uracil; Vesicular stomatitis Indiana virus; Xanthines | 1976 |
Purine transport in cultured-normal and mouse sarcoma virus-transformed rat kidney cells.
Topics: Adenine; Animals; Binding, Competitive; Biological Transport; Cell Line; Cell Transformation, Neoplastic; Diffusion; Gammaretrovirus; Guanine; Hypoxanthines; Kinetics; Mice; Purines; Rats; Sarcoma Viruses, Murine | 1977 |
Entamoeba histolytica: uptake of purine bases and nucleosides during axenic growth.
Topics: Adenine; Adenosine; Animals; Culture Media; Entamoeba histolytica; Guanine; Guanosine; Hypoxanthines; Inosine; Purine Nucleosides; Purines | 1978 |
Heterogeneity of Epstein-Barr virus. III. Comparison of a transforming and a nontransforming virus by partial denaturation mapping of their DNAs.
Topics: Adenine; Cell Transformation, Viral; Cytosine; DNA, Viral; Guanine; Herpesvirus 4, Human; Nucleic Acid Denaturation; Thymine | 1978 |
Synthesis and metabolic fate of purine nucleotides in cultured fibroblasts from normal subjects and from purine overproducing mutants.
Topics: Adenine; Cells, Cultured; Fibroblasts; Formates; Guanine; Humans; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Purine Nucleotides; Purine-Pyrimidine Metabolism, Inborn Errors; Ribose-Phosphate Pyrophosphokinase; Skin | 1978 |
Alterations in purine metabolism in cultured fibroblasts with HGPRT deficiency and with PRPP synthetase superactivity.
Topics: Adenine; Cells, Cultured; Fibroblasts; Gout; Guanine; Humans; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Mutation; Phosphotransferases; Purines; Ribose-Phosphate Pyrophosphokinase; Skin | 1979 |
Formaldehyde as a probe of DNA structure. I. Reaction with exocyclic amino groups of DNA bases.
Topics: Adenine; Amines; Chemical Phenomena; Chemistry; Cytosine; Deoxyribonucleosides; Deoxyribonucleotides; DNA; Formaldehyde; Guanine; Hydrogen-Ion Concentration; Kinetics; Ribonucleotides; Thermodynamics | 1975 |
The photochemistry of purine components of nucleic acids. I. The efficiency of photolysis of adenine and guanine derivatives in aqueous solution.
Topics: Adenine; Adenine Nucleotides; Adenosine; Guanine; Guanine Nucleotides; Guanosine; Hydrogen-Ion Concentration; Oxygen; Partial Pressure; Photolysis; Quantum Theory; Spectrophotometry, Ultraviolet; Temperature; Time Factors | 1975 |
A new method for sequencing DNA.
Topics: Adenine; Base Sequence; Biochemical Phenomena; Biochemistry; Cytosine; DNA; DNA Restriction Enzymes; Guanine; Hydrazines; Methods; Nucleic Acid Hybridization; Thymine | 1977 |
Identification of the major adducts formed by reaction of benzo(a)pyrene diol epoxide with DNA in vitro.
Topics: Adenine; Animals; Benzopyrenes; Cattle; Chemical Phenomena; Chemistry; Cytosine; DNA; Epoxy Compounds; Guanine; In Vitro Techniques; Mass Spectrometry | 1977 |
[Normal and modified nucleobases excreted in urine of patients with chronic nyeloproliferative disorders (author's transl)].
Topics: Adenine; Adult; Aged; Female; Guanine; Humans; Leukemia, Myeloid; Leukocyte Count; Male; Middle Aged; Myeloproliferative Disorders; Pancytopenia; Polycythemia Vera | 1979 |
Reaction of nucleosome DNA with dimethyl sulfate.
Topics: Adenine; Animals; Chromatin; DNA; Guanine; Male; Methylation; Nucleic Acid Conformation; Sulfuric Acid Esters | 1979 |
Purine reutilization in phytohemagglutinin-stimulated human T-lymphocytes.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine; Adenosine Deaminase; Adenosine Kinase; Guanine; Humans; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Kinetics; Lectins; Lymphocyte Activation; Nucleotides; T-Lymphocytes | 1978 |
De novo purine ribonucleotide biosynthesis in adult Angiostrongylus cantonensis (Nematoda: Metastrongyloidea).
Topics: Adenine; Adenosine; Angiostrongylus; Animals; Female; Guanine; Hypoxanthine; Hypoxanthines; Inosine; Kinetics; Male; Metastrongyloidea; Purine Nucleotides | 1979 |
Altered synthesis and catabolism of purine nucleotides in regulatory mutants of Saccharomyces cerevisiae.
Topics: Adenine; Energy Metabolism; Glycine; Guanine; Hypoxanthines; Mutation; Purine Nucleotides; Purines; Saccharomyces cerevisiae | 1977 |
Purine metabolism in Saccharomyces cerevisiae.
Topics: Adenine; Glycine; Guanine; Hypoxanthines; Inosine; Purines; Ribonucleosides; Ribonucleotides; RNA; Saccharomyces cerevisiae; Xanthines | 1977 |
[Genetic control of Escherichia coli K-12 strains' assimilation of 2,6-diaminopurine as a purine source].
Topics: 2-Aminopurine; Adenine; Adenine Phosphoribosyltransferase; Escherichia coli; Guanine; Hypoxanthines; Mutation; Transduction, Genetic | 1977 |
A study of unwinding of DNA and shielding of the DNA grooves by RNA polymerase by using methylation with dimethylsulphate.
Topics: Adenine; Binding Sites; Coliphages; DNA-Directed RNA Polymerases; DNA, Viral; Escherichia coli; Guanine; Methane; Methylation; Oligodeoxyribonucleotides; Poly dA-dT; Sulfuric Acids; Uridine Monophosphate | 1978 |
[Study of the methylation process and DNA methylase specificity in Shigella].
Topics: Adenine; Bacteriophages; DNA (Cytosine-5-)-Methyltransferases; DNA, Bacterial; DNA, Viral; Guanine; Methyltransferases; Shigella; Shigella sonnei; Substrate Specificity | 1978 |
Yeast tRNA Leu UAG. Purification, properties and determination of the nucleotide sequence by radioactive derivative methods.
Topics: Adenine; Base Sequence; Guanine; Leucine; Nucleic Acid Conformation; Oligoribonucleotides; Ribonucleases; Ribonucleotides; RNA, Transfer; Saccharomyces cerevisiae; Uracil | 1979 |
Purine metabolism in trypanosomatids.
Topics: Adenine; Adenine Nucleotides; Animals; Crithidia; Glycine; Guanine; Guanine Nucleotides; Purine Nucleotides; Purines; Pyrimidine Nucleotides; Species Specificity; Trypanosoma cruzi | 1979 |
[Reactions of protonation and alkylation of nucleic acid bases].
Topics: Adenine; Alkylation; Guanine; Protons | 1977 |
Incorporation of purine bases by intact red blood cells.
Topics: Adenine; Biological Transport; Erythrocytes; Guanine; Humans; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Kinetics; Phosphoribosyl Pyrophosphate; Purine-Nucleoside Phosphorylase | 1977 |
Purine degradation in Pseudomonas aeruginosa and Pseudomonas testosteroni.
Topics: Adenine; Adenosine Monophosphate; Allantoin; Aminohydrolases; Aspartate Kinase; Cell Division; Guanine; Pseudomonas; Pseudomonas aeruginosa; Purines; Species Specificity; Urate Oxidase; Xanthine Dehydrogenase | 1977 |
Excision repair of DNA base damage in human cells treated with the chemical carcinogen 4-nitroquinoline 1-oxide.
Topics: 4-Nitroquinoline-1-oxide; Adenine; Amnion; Cell Line; DNA; DNA Repair; DNA, Neoplasm; Guanine; Humans; Nitroquinolines; Xeroderma Pigmentosum | 1977 |
Excision of 4-nitroquinoline 1-oxide damage and transformed in mouse cells.
Topics: 4-Nitroquinoline-1-oxide; Adenine; Cell Transformation, Neoplastic; Cells, Cultured; DNA Repair; DNA, Neoplasm; Guanine; Hydroxyurea; Nitroquinolines; Thymidine; Xeroderma Pigmentosum | 1977 |
Mapping adenines, guanines, and pyrimidines in RNA.
Topics: Adenine; Base Sequence; Chemical Phenomena; Chemistry; Cytosine; Guanine; Hydrolysis; Oligoribonucleotides; Ribonuclease T1; Ribonucleases; RNA, Ribosomal; Saccharomyces cerevisiae; Uracil | 1977 |
Mechanism for fatty liver induction in rats fed arginine deficient diets.
Topics: Adenine; Animals; Arginine; Body Weight; Cholesterol; Citrates; Fatty Liver; Female; Guanine; Lipid Metabolism; Male; Orotic Acid; Phospholipids; Rats; Triglycerides; Urea | 1979 |
Antibody-nucleic acid complexes. Immunospecific recognition of 7-methylguanine- and N6-methyladenine-containing 5'-terminal oligonucleotides of mRNA.
Topics: Adenine; Adenoviruses, Human; Antigen-Antibody Complex; Cell Line; Cell Transformation, Viral; Guanine; Humans; Oligoribonucleotides; RNA, Messenger | 1979 |
Adenine induced granulocytosis in the rabbit.
Topics: Adenine; Animals; Granulocytes; Guanine; Leukocyte Count; Male; Rabbits | 1979 |
Purine metabolism in human lymphocytes.
Topics: Adenine; Adenine Nucleotides; Guanine; Humans; Hypoxanthines; Lymphocytes; Purines | 1979 |
A reconsideration of the possibility of the specific pairing of base pairs.
Topics: Adenine; Base Sequence; Cytosine; Deoxyribonucleotides; Guanine; Hydrogen Bonding; Models, Chemical; Nucleic Acid Conformation; Thymine | 1979 |
Rapid determination of methylated purines in DNA treated with N-methyl-N-nitrosourea using high-performance liquid chromatography.
Topics: Adenine; Chromatography, High Pressure Liquid; DNA; Guanine; Methylation; Methylnitrosourea; Nitrosourea Compounds | 1979 |
Absorption and metabolism of orally administered purines in fed and fasted rats.
Topics: Adenine; Allantoin; Animals; Diet; Fasting; Guanine; Hypoxanthines; Intestinal Absorption; Male; Purines; Rats; Tissue Distribution; Xanthines | 1979 |
Isocratic separation of DNA bases and deoxyribonucleosides by high-performance liquid chromatography on anex OSTION.
Topics: Adenine; Anion Exchange Resins; Chromatography, High Pressure Liquid; Cytosine; Deoxyribonucleosides; Guanine; Methods; Thymine | 1979 |
Mode of anticoccidial action of arprinocid.
Topics: Adenine; Animals; Benzyl Compounds; Chick Embryo; Chickens; Coccidiostats; Eimeria; Folic Acid Antagonists; Formates; Glucosephosphate Dehydrogenase; Guanine; HeLa Cells; Hypoxanthines; Inosine; Male | 1979 |
The stability of methylated purines and of methylphosphotriesters in the DNA of V79 cells after treatment with N-methyl-N-nitrosourea.
Topics: Adenine; Animals; Cells, Cultured; Cricetinae; Cricetulus; DNA; DNA Repair; Esters; Guanine; Methylnitrosourea; Nitrosourea Compounds; Purines | 1979 |
Ring current shifts in GU base pairs.
Topics: Adenine; Base Composition; Chemical Phenomena; Chemistry; DNA; Guanine; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; RNA, Transfer | 1979 |
Effect of chronic N,N-diethylnitrosamine on the excision of O6-ethylguanine from rat liver DNA.
Topics: Adenine; Alkylation; Animals; Diethylnitrosamine; DNA; DNA Repair; Guanine; Liver; Male; Nitrosamines; Rats | 1979 |
Synthetic models of deoxyribonucleic acid complexes with antimalarial compounds. Comparative ultraviolet and proton magnetic resonance study of quinoline-base, quinoline-quinoline, and base-base stacking interactions.
Topics: Adenine; Chemical Phenomena; Chemistry; Chloroquine; DNA; Guanine; Magnetic Resonance Spectroscopy; Molecular Conformation; Quinolines; Spectrophotometry, Ultraviolet | 1979 |
Utilization of purines by an HPRT variant in an intelligent, nonmutilative patient with features of the Lesch-Nyhan syndrome.
Topics: Adenine; Adult; Carbon Radioisotopes; Fibroblasts; Guanine; Humans; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Lesch-Nyhan Syndrome; Male; Purines | 1979 |
Urate-binding proteins in plasma studied by affinity chromatography.
Topics: Adenine; Carrier Proteins; Chromatography, Affinity; Guanine; Humans; Indicators and Reagents; Uric Acid; Xanthines | 1979 |
Prevention of G:C pairing in mouse DNA by complete blocking of guanine residues with glyoxal. Availability of cytosine, adenine and thymine for hydrogen bonding with added unmodified polynucleotides.
Topics: Adenine; Aldehydes; Animals; Cytosine; DNA, Single-Stranded; Glyoxal; Guanine; Hydrogen Bonding; Mice; Molecular Weight; Polynucleotides; Thymine | 1978 |
The nucleotide sequence of oocyte 5S DNA in Xenopus laevis. I. The AT-rich spacer.
Topics: Adenine; Animals; Base Sequence; Cytosine; DNA; Female; Genes; Guanine; Oocytes; Ovum; RNA, Ribosomal; Thymine; Xenopus | 1978 |
A-T rich sequences in vertebrate DNA. A possible explanation of q-banding in metaphase chromosomes.
Topics: Adenine; Animals; Cattle; Chickens; Chromosome Banding; Chromosomes; Cytosine; DNA; Guanine; Mice; Microscopy, Electron; Nucleic Acid Conformation; Nucleic Acid Denaturation; Thymine | 1978 |
[Analysis of normal and methylated urinary nucleobases: a new criterion for diagnosis and follow-up of malignancies (author's transl)].
Topics: Adenine; Adolescent; Adult; Child; Child, Preschool; Creatinine; Guanine; Humans; Infant; Neoplasms; Purines | 1979 |
Direct proton exchange between complementary nucleic acid bases.
Topics: Adenine; Bromouracil; Chemical Phenomena; Chemistry; Cytosine; Guanine; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Nucleic Acids; Protons; Purines; Pyrimidines | 1978 |
Potentiation of ribavirin-induced teratogenesis by natural purines.
Topics: Abnormalities, Drug-Induced; Adenine; Animals; Cricetinae; Dose-Response Relationship, Drug; Drug Synergism; Embryo Loss; Female; Guanine; Mesocricetus; Pregnancy; Purines; Ribavirin; Ribonucleosides | 1978 |
Removal of methylated purines from rat liver DNA after administration of dimethylnitrosamine.
Topics: Adenine; Animals; Chromatin; Deoxyribonucleases; Dimethylnitrosamine; DNA; Dose-Response Relationship, Drug; Female; Guanine; Liver; Methylation; Nitrosamines; Rats | 1978 |
[Characteristics of the spiral sphere transition in DNA in a region of inversion of the relative stability of GC- and AT-pairs caused by Cu2+ and Mn2+ ions].
Topics: Adenine; Animals; Base Sequence; Cations, Divalent; Cattle; Chromosome Inversion; Copper; Cytosine; DNA; Dose-Response Relationship, Drug; Guanine; Manganese; Nucleic Acid Denaturation; Temperature; Thymine; Time Factors | 1978 |
[Complexes with transfer of the nucleic acid base charge].
Topics: Adenine; Base Sequence; Crystallization; Cytosine; Drug Interactions; Electrons; Guanine; Nitriles; Nucleic Acid Conformation; Nucleic Acids; Spectrophotometry, Infrared | 1978 |
Characterization of a guanine-sensitive mutant defective in adenylo-succinate synthetase activity.
Topics: Adenine; Aspartic Acid; Cell Line; Culture Media; Drug Resistance; Genetic Complementation Test; Guanine; Inosine Monophosphate; Ligases; Mutation | 1978 |
Transport and accumulation of purine bases by Crithidia fasciculata.
Topics: Adenine; Adenine Nucleotides; Animals; Azides; Biological Transport; Cyanides; Dinitrophenols; Eukaryota; Guanine; Guanine Nucleotides; Hypoxanthines; Kinetics | 1978 |
Hydration scheme of the complementary base-pairs of DNA.
Topics: Adenine; Chemical Phenomena; Chemistry; Cytosine; DNA; Guanine; Hydrogen Bonding; Nucleic Acid Conformation; Thymine | 1978 |
Differences in incorporation of nucleic acid bases and nucleosides by various Mycoplasma and Acholeplasma species.
Topics: Acholeplasma laidlawii; Adenine; Cytosine; Deoxyribonucleosides; Guanine; Mycoplasma; Nucleosides; Purines; Pyrimidinones; Ribonucleosides; Uracil | 1978 |
Nucleotides contiguous to AUG affect translational initiation.
Topics: Adenine; Base Sequence; Cell Line; Codon; Guanine; Kinetics; Oligoribonucleotides; Peptide Chain Initiation, Translational; Ribosomes; RNA, Messenger; Uracil | 1978 |
Incorporation of purines and purine precursors into the nucleotide pool of isolated bone cells.
Topics: Adenine; Animals; Animals, Newborn; Bone and Bones; Formates; Glycine; Guanine; Hypoxanthines; Purine Nucleotides; Purines; Rats; RNA; Skull | 1978 |
Stereospecific binding of triostin A to nucleic acid purine base derivatives.
Topics: Adenine; Anti-Bacterial Agents; Chemical Phenomena; Chemistry; DNA; Guanine; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Molecular Conformation; Nucleic Acid Conformation; Purines; Quinoxalines; Spectrophotometry, Infrared | 1978 |
The influence of purines on plasma lecithin: cholesterole acyltransferase activity in the rat.
Topics: Acyltransferases; Adenine; Animals; Guanine; Hypoxanthines; Microsomes, Liver; Purines; Rats; Sterol O-Acyltransferase; Uric Acid; Xanthines | 1978 |
Effect of hypophysectomy on persistence of methylated purines in rat liver deoxyribonucleic acid after administration of dimethylnitrosamine.
Topics: Adenine; Animals; Dimethylnitrosamine; DNA; DNA Repair; Female; Growth Hormone; Guanine; Hypophysectomy; Liver; Methylation; Nitrosamines; Rats | 1978 |
1,2-Dimethylhydrazine-induced methylation of DNA bases in various rat organs and the effect of pretreatment with disulfiram.
Topics: Adenine; Animals; Colon; Dimethylhydrazines; Disulfiram; DNA; Female; Guanine; Methylation; Methylhydrazines; Organ Specificity; Rats | 1979 |
Transfer of purines from liver to erythrocytes. In vivo and in vitro studies.
Topics: Adenine; Animals; Biological Transport; Erythrocytes; Glycine; Guanine; Hypoxanthines; Kinetics; Liver; Liver Regeneration; Male; Purines; Rats | 1979 |
Removal of minor methylation products 7-methyladenine and 3-methylguanine from DNA of Escherichia coli treated with dimethyl sulphate.
Topics: Adenine; DNA (Cytosine-5-)-Methyltransferases; DNA, Bacterial; Escherichia coli; Guanine; Sulfuric Acids | 1976 |
DNA crosslinks, single-strand breaks and effects on bacteriophage T4 survival from tritium decay of (2-3H)adenine, (8-3H)adenine and (8-3H)guanine.
Topics: Adenine; Binding Sites; Coliphages; DNA, Bacterial; DNA, Single-Stranded; DNA, Viral; Escherichia coli; Freezing; Guanine; Isotope Labeling; Mathematics; Molecular Weight; Nucleic Acid Conformation; Nucleic Acid Renaturation; Tritium | 1976 |
Occurrence of a regulatory deficiency in purine biosynthesis among pur A mutants of Salmonella typhimurium.
Topics: Adenine; Genes, Regulator; Genetic Complementation Test; Genetic Linkage; Guanine; Mutation; Phenotype; Purine Nucleotides; Salmonella typhimurium | 1976 |
Utilization of dietary nucleic acid purines for nucleotide and nucleic acid synthesis in the mouse.
Topics: Adenine; Administration, Oral; Animals; DNA; Female; Guanine; Intestine, Small; Kinetics; Liver; Mice; Mice, Inbred ICR; Muscles; Organ Specificity; Purines; RNA; Saccharomyces cerevisiae | 1976 |
Purine metabolism in neisseria meningitidis. 4. Interconversion of purine ribonucleotides.
Topics: Adenine; DNA, Bacterial; Guanine; Histidine; Ketone Oxidoreductases; Ligases; Lyases; Neisseria meningitidis; Proline; Purine Nucleotides; RNA, Bacterial | 1975 |
[Studies on the growth requirements of enterococci (author's transl)].
Topics: Adenine; Amino Acids, Essential; Culture Media; Enterococcus faecalis; Glutamates; Guanine; Species Specificity; Threonine; Uracil | 1975 |
Escherichia coli mutants deficient in guanine-xanthine phosphoribosyltransferase.
Topics: Adenine; Cell-Free System; Escherichia coli; Genes; Guanine; Hypoxanthines; Mutation; Pentosyltransferases; Purine Nucleotides; Purine-Nucleoside Phosphorylase; Xanthines | 1976 |
Detection reagent for adenine, guanine, uracil, cytosine and their alkylated bases, nucleotides and nucleosides on thin-layer plates.
Topics: Adenine; Alkylation; Chlorine; Chromatography, Thin Layer; Cytosine; Guanine; Indicators and Reagents; Nucleosides; Nucleotides; Uracil | 1977 |
Synthetic models of DNA complexes with antimalarial compounds. 2. The problem of guanine specificity in chloroquine binding.
Topics: Adenine; Binding Sites; Chemical Phenomena; Chemistry; Chloroquine; DNA; Guanine; Models, Chemical; Spectrophotometry, Ultraviolet; Temperature; Water | 1977 |
Time dependence of ethionine-induced changes in rat liver transfer RNA methylation.
Topics: Adenine; Animals; Cytosine; Drug Interactions; Ethionine; Female; Guanine; Liver; Methylation; Rats; RNA, Transfer; S-Adenosylmethionine; tRNA Methyltransferases; Uracil | 1977 |
Rapid, quantitative separation by high-performance liquid chromatography of methylated bases in transfer RNA.
Topics: Adenine; Buffers; Chromatography, High Pressure Liquid; Cytosine; Guanine; Methylation; RNA, Transfer; Temperature; Time Factors; Uracil | 1977 |
The protein and nucleic acid of beet yellows virus.
Topics: Adenine; Amino Acids; Capsid; Cytosine; Electrophoresis, Polyacrylamide Gel; Guanine; Molecular Weight; Plant Viruses; RNA, Viral; Spectrophotometry, Ultraviolet; Uracil; Viral Proteins | 1977 |
Separation of alkylated guanines, adenines, uracils and cytosines by thin-layer chromatography.
Topics: Adenine; Alkylation; Ammonia; Chromatography, Thin Layer; Cytosine; Guanine; Methods; Uracil | 1977 |
Coordinate regulation of the proximal and distal steps of the pathway of purine synthesis de nono in WI-L2 human lymphoblasts.
Topics: Adenine; Adenine Nucleotides; Adenosine Kinase; Azaserine; Cell Line; Feedback; Formates; Guanine; Hypoxanthines; Inosine Nucleotides; Kinetics; Ligases; Lymphocytes; Phosphoribosyl Pyrophosphate; Purine Nucleotides; Purines; Thioinosine | 1977 |
Isolated rat liver cells - purine metabolism and effects of fructose.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Animals; Fructose; Guanine; Guanine Nucleotides; Hypoxanthines; Liver; Oxygen Consumption; Phosphates; Purines; Rats | 1977 |
Proton magnetic resonance studies of specific association of nucleic acid constitutent bases in a nonaqueous solvent. Utility of DTBN radical to probe the affinity of hydrogen bonding involved in complementary base pairs1.
Topics: Adenine; Cytosine; Guanine; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Nitrogen Oxides; Solvents; Uracil | 1977 |
Analytical potentials from "ab initio" computations for the interaction between biomolecules. 2. Water with the bases of DNA.
Topics: Adenine; Cytosine; Electrochemistry; Guanine; Mathematics; Thymine; Water | 1977 |
Simple micro ion-exchange chromatography procedures for the individual groups of pyrimidines and purines.
Topics: Adenine; Chromatography, Ion Exchange; Cytosine; Guanine; Purines; Pyrimidines | 1977 |
Hydrogen bonding between nucleic acid bases and carboxylic acids.
Topics: Adenine; Butyrates; Cytosine; Guanine; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Spectrophotometry, Ultraviolet; Uracil | 1977 |
Secondary structural modifications as a consequence of in vitro acetylation and phenanthrylation of DNA by the ultimate carcinogen N-acetoxy-N-2-acetylaminophenanthrene.
Topics: Acetylation; Adenine; Carcinogens; DNA; Guanine; In Vitro Techniques; Nucleic Acid Conformation; Nucleic Acid Denaturation; Phenanthrenes; Thermodynamics | 1977 |
Effects of ultrasound on nucleic acid bases.
Topics: Adenine; Cytosine; Gases; Guanine; Kinetics; Structure-Activity Relationship; Thymine; Time Factors; Ultrasonics; Uracil | 1977 |
Accumulation of O6-methylguanine in non-target-tissue deoxyribonucleic acid during chronic administration of dimethylnitrosamine.
Topics: Adenine; Animals; Dimethylnitrosamine; DNA; Guanine; Kidney; Liver; Lung; Male; Nitrosamines; Purines; Rats; Tissue Distribution | 1977 |
Purine metabolism in isolated rat hepatocytes.
Topics: Adenine; Adenine Nucleotides; Adenosine; Allantoin; Animals; Guanine; Guanine Nucleotides; Hypoxanthines; Liver; Oxygen Consumption; Purines; Rats | 1977 |
Purification and biochemical properties of Egtved viral RNA.
Topics: Adenine; Centrifugation, Density Gradient; Cytosine; Guanine; Nucleic Acid Conformation; Rhabdoviridae; Ribonucleases; RNA, Viral; Uracil | 1977 |
Purine metabolism in thioguanine-resistant glioma cells.
Topics: Adenine; Amidophosphoribosyltransferase; Cell Line; Guanine; Hypoxanthine Phosphoribosyltransferase; Neuroglia; Phosphoribosyl Pyrophosphate; Purines | 1976 |
Letter: An interpretation of radiation damage measurements in DNA bases.
Topics: Adenine; Cytosine; DNA; Electrons; Guanine; Microscopy, Electron, Scanning; Radiation Effects; Thymine | 1976 |
RNAs of influenza A, B, and C viruses.
Topics: Adenine; Animals; Chick Embryo; Culture Techniques; Cytidine; Deoxyribonucleases; Guanine; Molecular Weight; Orthomyxoviridae; Ribonucleases; RNA, Viral; Uracil | 1976 |
On the atomic or "local" contributions to proton chemical shifts due to the anisotropy of the diamagnetic susceptibility of the nucleic acid base.
Topics: Adenine; Animals; Cytosine; Guanine; Magnetics; Molecular Conformation; Nucleic Acid Conformation; Purines; Pyrimidines; Ranidae; Uracil | 1976 |
[Ionization potentials of nucleic acid nitrogenous bases].
Topics: Adenine; Cytosine; Guanine; Ions; Methylation; Thymine; Uracil | 1976 |
Peculiarities of the secondary structure of bacteriophage DNA in situ. VI. The reaction of SD phage with glyoxal.
Topics: Adenine; Aldehydes; Bacteriophages; Chemical Phenomena; Chemistry; Circular Dichroism; Cytosine; DNA, Viral; Formaldehyde; Glyoxal; Guanine; Magnesium; Nucleic Acid Conformation; Nucleic Acid Renaturation; Optical Rotatory Dispersion; Sodium; Spectrophotometry, Ultraviolet; Temperature | 1976 |
Fluorescent labeling of DNA in solution with covalently bound acriflavin.
Topics: Acridines; Acriflavine; Adenine; Binding Sites; DNA; Fibroblasts; Guanine; Humans; Hypoxanthines; Polydeoxyribonucleotides; Spectrometry, Fluorescence; Sulfites; Temperature | 1976 |
Characterization of the 5' termini of hn RNA in mouse L cells: implications for processing and cap formation.
Topics: Adenine; Cytosine; Guanine; L Cells; Models, Biological; RNA, Messenger; RNA, Neoplasm; Transcription, Genetic; Uracil | 1976 |
Isothermal luminescence and thermoluminescence of nucleic acid bases following gamma-irradiation.
Topics: Adenine; Cytosine; Gamma Rays; Guanine; Luminescence; Models, Chemical; Purines; Pyrimidines; Radiation, Ionizing; Spectrum Analysis; Temperature | 1976 |
Synthesis of VA RNA in productive and abortive infections with adenovirus type 12.
Topics: Adenine; Adenoviridae; Cell Line; Cytosine; Guanine; Oligonucleotides; RNA; RNA, Viral; Uracil | 1976 |
Methylated purines in the deoxyribonucleic acid of various Syrian-golden-hamster tissues after administration of a hepatocarcinogenic dose of dimethylnitrosamine.
Topics: Adenine; Animals; Cricetinae; Dimethylnitrosamine; DNA; Guanine; Kidney; Liver; Liver Neoplasms; Lung; Male; Mesocricetus; Neoplasms, Experimental; Nitrosamines; Purines | 1976 |
The effects of added purines on urate and purine synthesis de novo by isolated chick liver, kidney and lymphoid cells.
Topics: Adenine; Adenosine Monophosphate; Animals; Chickens; Formates; Glycine; Guanine; Guanine Nucleotides; In Vitro Techniques; Inosine; Inosine Monophosphate; Kidney; Liver; Lymphoid Tissue; Phosphoribosyl Pyrophosphate; Purines; Stimulation, Chemical; Uric Acid | 1976 |
Repeating units of Xenopus laevis oocyte-type 5S DNA are heterogeneous in length.
Topics: Adenine; Animals; Cytosine; DNA; DNA Restriction Enzymes; Electrophoresis, Polyacrylamide Gel; Female; Guanine; Nucleic Acid Denaturation; Oocytes; Ovum; Thymine; Xenopus | 1976 |
Effect of chronic administration of dimethylnitrosamine on the excision of O6-methylguanine from rat liver DNA.
Topics: Adenine; Alkylation; Animals; Dimethylnitrosamine; DNA; DNA Repair; Guanine; Liver; Male; Methylnitrosourea; Nitrosamines; Rats | 1976 |
One step syntheses of adenine, xanthine and guanine from phenylazomalonic acid derivatives.
Topics: Adenine; Guanine; Malonates; Methods; Xanthines | 1976 |
Consequences of methotrexate inhibition of purine biosynthesis in L5178Y cells.
Topics: Adenine; Adenosine Triphosphate; Animals; Cell Line; Cytosine Nucleotides; Depression, Chemical; DNA; Guanine; Guanosine Triphosphate; Hypoxanthines; Leucine; Leukemia, Lymphoid; Methotrexate; Mice; Purines; RNA; Thymidine; Time Factors; Uracil Nucleotides; Uridine | 1975 |
Effects of nucleoside analogs on purine nucleotide metabolism.
Topics: Adenine; Animals; Anti-Bacterial Agents; Carcinoma, Ehrlich Tumor; Guanine; Hypoxanthines; IMP Dehydrogenase; Mice; Nucleosides; Phosphoribosyl Pyrophosphate; Purine Nucleotides; Ribonucleotides; Structure-Activity Relationship | 1975 |
Adducts between the carcinogen 2-acetamidophenanthrene and adenine and guanine of DNA.
Topics: Acetamides; Adenine; Carcinogens; Chemical Phenomena; Chemistry; Chromatography, Gel; Deoxyadenosines; Deoxyribonucleosides; DNA; Esters; Guanine; Guanosine; Hydroxamic Acids; Phenanthrenes; Structure-Activity Relationship; Sulfates | 1975 |
Purine metabolism in vertebrate blood cells.
Topics: Adenine; Amphibians; Animals; Anura; Birds; Dogs; Erythrocytes; Fishes; Glycine; Guanine; Hypoxanthine Phosphoribosyltransferase; Imidazoles; Purines; Rana catesbeiana; Reptiles; Species Specificity | 1975 |
Specific excision of ethylated purines from DNA of Escherichia coli treated with N-ethyl-N-nitrosourea.
Topics: Adenine; DNA Replication; DNA, Bacterial; Escherichia coli; Ethanol; Ethylnitrosourea; Guanine; Methylnitronitrosoguanidine; Methylnitrosourea; Nitrosourea Compounds | 1975 |
Physicochemical properties of kinetoplast DNA from Crithidia acanthocephali. Crithidia luciliae, and Trypanosoma lewisi.
Topics: Adenine; Alkalies; Animals; Base Sequence; Cytosine; DNA; DNA, Circular; Eukaryota; Guanine; Nucleic Acid Conformation; Nucleic Acid Denaturation; Nucleic Acid Hybridization; Nucleic Acid Renaturation; Thymine; Trypanosoma lewisi | 1975 |
The molecular mechanism of benzimidazole mutagenicity: in vitro studies on transcription and translation.
Topics: Adenine; Amino Acids; Benzimidazoles; DNA-Directed RNA Polymerases; Escherichia coli; Guanine; Mutagens; Peptide Biosynthesis; Protein Biosynthesis; Ribonucleotides; Templates, Genetic; Transcription, Genetic | 1975 |
Doublet frequencies in sequenced nucleic acids.
Topics: Adenine; Animals; Base Sequence; Biological Evolution; Cell Line; Coliphages; Cytosine; DNA; Escherichia coli; Guanine; Humans; Markov Chains; Models, Chemical; Rabbits; Rats; RNA, Bacterial; RNA, Ribosomal; RNA, Transfer; RNA, Viral; Species Specificity; Statistics as Topic; Uracil | 1975 |
1-Amino-omega-trifluoroacetamidoalkanes: new reagents for use in preparing ligands for affinity chromatography.
Topics: Acetamides; Adenine; Alkanes; Chromatography, Affinity; Guanine; Ligands | 1975 |
[Oligonucleotides of human thrombocytes and their participation in the release reaction induced by thrombin].
Topics: Adenine; Blood Coagulation; Blood Platelets; Cytosine; Guanine; Humans; Oligonucleotides; Thrombin; Uracil | 1975 |
[The effect of orotic acid and vitamin A on 2C-14-orotic acid incorporation into the acid-soluble fraction and nucleic acids of white rat tissues].
Topics: Adenine; Animals; Brain; Brain Chemistry; Carbon Radioisotopes; DNA; Guanine; Kidney; Liver; Male; Orotic Acid; Rats; RNA; Spleen; Testis; Uracil; Vitamin A | 1975 |
Methylation of DNA in various organs of C57B1 mice by a carcinogenic dose of N-methyl-N-nitrosourea and stabiltty of some methylation products up to 18 hours.
Topics: Adenine; Animals; Bone Marrow; Carbon Radioisotopes; Chromatography, Affinity; Chromatography, Paper; DNA; Female; Guanine; Injections, Intraperitoneal; Intestine, Small; Kidney; Liver; Lung; Methylation; Methylnitrosourea; Mice; Mice, Inbred C57BL; Nitrosourea Compounds; Spleen; Thymus Gland; Time Factors; Tritium | 1975 |
Rapid determination of hypoxanthine-guanine-phosphoribosyl transferase in human fibroblasts and amniotic cells.
Topics: Adenine; Amniotic Fluid; Carbon Radioisotopes; Chromatography, Thin Layer; Fibroblasts; Guanine; Humans; Hypoxanthines; Lesch-Nyhan Syndrome; Methods; Pentosyltransferases | 1975 |
Separation of arabinosyl, ribosyl, and deoxyribosyl purine nucleotides by thin-layer chromatography.
Topics: Adenine; Arabinose; Chromatography, Thin Layer; Deoxyribonucleotides; Guanine; Hypoxanthines; Methods; Purine Nucleotides; Ribonucleotides | 1975 |
Synthetic spectroscopic models. Intramolecular stacking interactions between indole and connected nucleic acid bases. Hypochromism and fluorescence.
Topics: Adenine; Base Sequence; Cytosine; Guanine; Models, Chemical; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Thymine; Tryptophan | 1975 |
Distribution of repetitious DNA in randomly growing and synchronized Chinese hamster cells.
Topics: Adenine; Animals; Base Sequence; Blood Proteins; Cell Division; Cell Fractionation; Cell Line; Centrifugation, Density Gradient; Chromatography; Cricetinae; Culture Media; Cytosine; DNA; DNA, Single-Stranded; Electrophoresis, Paper; Guanine; Hydroxyapatites; Lung; Nucleic Acid Denaturation; Nucleic Acid Renaturation; Phosphorus Radioisotopes; Thymidine; Thymine; Tritium | 1975 |
Mouse neuroblastoma adenylate cyclase. Adenosine and adenosine analogues as potent effectors of adenylate cyclase activity.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Adenylyl Cyclases; Animals; Clone Cells; Cytidine; Guanine; Guanosine; Kinetics; Mice; Neuroblastoma; Phosphorus Radioisotopes; Prostaglandins E; Ribose; Theophylline; Tolazoline; Uridine; Yohimbine | 1975 |
Insoluble collagen of methylcholanthrene induced sarcoma.
Topics: Adenine; Amino Acids; Animals; Carbohydrates; Collagen; Guanine; Methylcholanthrene; Rats; Sarcoma, Experimental; Solubility; Spectrophotometry, Ultraviolet | 1975 |
[Adsorption chromatography of the nitrogenous bases of nucleic acids and their derivatives on sephadex G-10 columns].
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Azaguanine; Chromatography; Cytosine; Cytosine Nucleotides; Guanine; Hypoxanthines; Nucleic Acids; Nucleotides; Pyrimidine Nucleotides; Uracil; Xanthines | 1975 |
Individual variation in inosine triphosphate accumulation in human erythrocytes.
Topics: Adenine; Adolescent; Adult; Child; Child, Preschool; Erythrocytes; Female; Guanine; Humans; Hypoxanthines; Infant; Inosine Nucleotides; Intellectual Disability; Leukocytes; Male; Middle Aged; Purine Nucleosides | 1975 |
Biosynthesis of formycin. Formation of formycin from formycin B.
Topics: Adenine; Adenosine; Amino Acids; Antibiotics, Antineoplastic; Aspartic Acid; Fluorides; Formycins; Fumarates; Guanine; Guanosine; Inosine Nucleotides; Ligases; Lyases; Streptomyces | 1975 |
S-adenosylhomocysteine inhibition of three purified tRNA methyltransferases from rat liver.
Topics: Adenine; Animals; Guanine; Homocysteine; Isoenzymes; Kinetics; Liver; Male; Rats; S-Adenosylhomocysteine; Structure-Activity Relationship; tRNA Methyltransferases | 1975 |
Role of apurinic sites in the resistance of methylated oligodeoxyribonucleotides to degradation by spleen exonuclease.
Topics: Adenine; Binding Sites; Binding, Competitive; Chromatography, Gel; Chromatography, Paper; DNA; Exonucleases; Guanine; Kinetics; Methylation; Oligodeoxyribonucleotides; Oligonucleotides; Spleen; Time Factors | 1975 |
Unconventional nucleotide analogues. Part XIII. (2S,4S)-2-hydroxymethyl- and 2-carboxy-4-(purin-9-yl)pyrrolidines.
Topics: Adenine; Antineoplastic Agents; Guanine; Hydroxylation; Hypoxanthines; Methylation; Proline; Purine Nucleosides; Pyrrolidines | 1975 |
Some physicochemical properties of pike fry rhabdovirus RNA.
Topics: Adenine; Animals; Centrifugation, Density Gradient; Cytosine; Fishes; Guanine; Molecular Weight; RNA Viruses; RNA, Viral; Uracil | 1975 |
Cathodoluminescence of biological molecules, macromolecules and cells.
Topics: Adenine; Animals; Beta Particles; Cytosine; DNA; Female; Guanine; Luminescent Measurements; Mice; Microscopy, Electron, Scanning; Proteins; Quinacrine; Radiation, Ionizing; Thymine; Vagina | 1975 |
Biochemical characterization of cucumber green mottle mosaic virus ribonucleic acid.
Topics: Adenine; Base Sequence; Cytosine; Guanine; Mosaic Viruses; Plant Viruses; RNA, Viral; Tobacco Mosaic Virus; Uracil; Vegetables; Viral Proteins | 1976 |
Relative importance of alternative pathways of purine nucleotide biosynthesis in Ehrlich ascites tumor cells in vivo.
Topics: Adenine; Adenosine; AMP Deaminase; Animals; Carcinoma, Ehrlich Tumor; Glycine; Guanine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Mice; Pentosyltransferases; Purine Nucleotides | 1976 |
The reaction of 7,8-dihydro-7,8-dihydroxybenzo (a) pyrene-9,10-oxide with DNA in relation to the benzo (a) pyrene-DNA products isolated from cells.
Topics: Adenine; Benzopyrenes; Binding Sites; Cell Line; DNA; Guanine | 1976 |
Contrast in adenine uptake by chicken and rabbit erythrocytes in vitro.
Topics: Adenine; Adenine Nucleotides; Adenine Phosphoribosyltransferase; Animals; Blood Proteins; Cell Membrane Permeability; Chickens; Chromatography, Thin Layer; Erythrocytes; Guanine; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Phosphoribosyl Pyrophosphate; Rabbits; Temperature | 1992 |
On the proton transfer behavior of the primary oxidation product in irradiated DNA.
Topics: Adenine; DNA; Guanine; Hydrogen Bonding; Oxidation-Reduction; Protons | 1992 |
Comparative activity of various compounds against clinical strains of herpes simplex virus.
Topics: Acyclovir; Adenine; Animals; Antiviral Agents; Cidofovir; Cytopathogenic Effect, Viral; Cytosine; Dextran Sulfate; Guanine; HeLa Cells; Heparin; Humans; Nucleosides; Organophosphonates; Organophosphorus Compounds; Rabbits; Simplexvirus; Virus Replication | 1992 |
The acyclic nucleoside analogue penciclovir is a potent inhibitor of equine herpesvirus type 1 (EHV-1) in tissue culture and in a murine model.
Topics: Acyclovir; Adenine; Animals; Antiviral Agents; Cell Line; Drug Resistance, Microbial; Female; Guanine; Herpesviridae Infections; Herpesvirus 1, Equid; Lung; Mice; Mice, Inbred BALB C; Mutation; Organophosphonates; Organophosphorus Compounds; Rabbits; Thymidine Kinase | 1992 |
Solution conformation of a deoxynucleotide containing tandem G.A mismatched base pairs and 3'-overhanging ends in d(GTGAACTT)2.
Topics: Adenine; Base Sequence; Circular Dichroism; Deoxyribonucleotides; Guanine; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Nucleic Acid Conformation; Nucleic Acid Heteroduplexes; Phosphorus Isotopes; Protons; Solutions; Temperature | 1992 |
Mitochondrial DNA mutation and heteroplasmy in type I Leber hereditary optic neuropathy.
Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; Base Sequence; Blotting, Southern; DNA Mutational Analysis; DNA, Mitochondrial; Female; Follow-Up Studies; Guanine; Humans; Male; Middle Aged; Molecular Sequence Data; Mutation; NADH Dehydrogenase; Optic Atrophies, Hereditary; Pedigree; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length | 1992 |
A mutation in codon 717 of the CHO-K1 elongation factor 2 gene prevents the first step in the biosynthesis of diphthamide.
Topics: Adenine; Amino Acid Sequence; Animals; Arginine; Base Sequence; CHO Cells; Codon; Cricetinae; Glycine; Guanine; Histidine; Homozygote; Molecular Sequence Data; Mutation; Peptide Elongation Factor 2; Peptide Elongation Factors; Polymorphism, Restriction Fragment Length | 1992 |
The molecular basis of medium chain acyl-CoA dehydrogenase deficiency: survey and evolution of 985A----G transition, and identification of five rare types of mutation within the medium chain acyl-CoA dehydrogenase gene.
Topics: Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenases; Adenine; Alleles; Base Sequence; Biological Evolution; Cells, Cultured; Ethnicity; Fibroblasts; Genetic Variation; Guanine; Homozygote; Humans; Metabolism, Inborn Errors; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Skin Physiological Phenomena; Surveys and Questionnaires | 1992 |
Electron transfer from nucleobase electron adducts to 5-bromouracil. Is guanine an ultimate sink for the electron in irradiated DNA?
Topics: Adenine; Bromouracil; Cytosine; DNA; Electrons; Guanine; Hydrogen-Ion Concentration; Pulse Radiolysis; Thymidine; Thymine; Uracil | 1992 |
Black beta-thalassemia homozygotes with specific sequence variations in the 5' hypersensitive site-2 of the locus control region have high levels of fetal hemoglobin.
Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; Base Sequence; beta-Thalassemia; Black People; Child; Chromosomes, Human, Pair 11; Cytosine; DNA; Female; Fetal Hemoglobin; Genes; Genetic Variation; Globins; Guanine; Haplotypes; Homozygote; Humans; Male; Middle Aged; Mutation; Promoter Regions, Genetic; Thymine | 1992 |
Inhibitory effects of triphosphate derivatives of oxetanocin G and related compounds on eukaryotic and viral DNA polymerases and human immunodeficiency virus reverse transcriptase.
Topics: Adenine; Adenosine Triphosphate; Animals; Antiviral Agents; Base Sequence; Cattle; Guanine; Guanosine Triphosphate; HIV Reverse Transcriptase; Humans; Kinetics; Male; Molecular Sequence Data; Nucleic Acid Synthesis Inhibitors; Rats; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Viral Proteins | 1992 |
Conformation of guanine-8-oxoadenine base pairs in the crystal structure of d(CGCGAATT(O8A)GCG).
Topics: Adenine; Base Sequence; Guanine; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Oligodeoxyribonucleotides; X-Ray Diffraction | 1992 |
Hydration of DNA bases: analysis of crystallographic data.
Topics: Adenine; Base Sequence; Cytosine; DNA; Guanine; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Oligodeoxyribonucleotides; Thymine; Water | 1992 |
Base release from DNA and polynucleotides upon 193 nm laser excitation.
Topics: Adenine; Animals; Cattle; Cytosine; DNA; Dose-Response Relationship, Radiation; Guanine; Lasers; Poly A; Poly C; Poly G; Polyribonucleotides; Thymine | 1992 |
Very stable mismatch duplexes: structural and thermodynamic studies on tandem G.A mismatches in DNA.
Topics: Adenine; Base Sequence; DNA; Guanine; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Nucleic Acid Heteroduplexes; Thermodynamics | 1992 |
Genetic effects of oxidative DNA damage: comparative mutagenesis of 7,8-dihydro-8-oxoguanine and 7,8-dihydro-8-oxoadenine in Escherichia coli.
Topics: Adenine; Bacteriophage M13; Base Sequence; Chromatography, High Pressure Liquid; DNA Damage; DNA, Recombinant; Escherichia coli; Guanine; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutagenicity Tests; Mutagens; Oligodeoxyribonucleotides; Oxidation-Reduction; Restriction Mapping; Transformation, Bacterial | 1992 |
Prenatal diagnosis for the cystic fibrosis mutation 1717-1, G-->A using arms.
Topics: Adenine; Base Sequence; Chorionic Villi Sampling; Cystic Fibrosis; DNA Mutational Analysis; Female; Fetal Diseases; Guanine; Humans; Male; Molecular Sequence Data; Polymerase Chain Reaction; Pregnancy | 1992 |
A single-base change at a splice acceptor site in the ornithine aminotransferase gene causes abnormal RNA splicing in gyrate atrophy.
Topics: Adenine; Base Sequence; DNA; Female; Guanine; Gyrate Atrophy; Humans; Molecular Sequence Data; Mutation; Ornithine-Oxo-Acid Transaminase; Polymerase Chain Reaction; RNA Splicing | 1992 |
A low-affinity nucleobase transporter in the protozoan parasite Giardia intestinalis.
Topics: Adenine; Adenosine; Animals; Binding, Competitive; Carrier Proteins; Giardia lamblia; Guanine; Kinetics; Membrane Proteins; Nucleoside Transport Proteins; Temperature; Thymine | 1992 |
Deuterium exchange of operator 8CH groups as a Raman probe of repressor recognition: interactions of wild-type and mutant lambda repressors with operator OL1.
Topics: Adenine; Adenine Nucleotides; Amino Acid Sequence; Bacteriophage lambda; Base Sequence; Deuterium; DNA Probes; DNA-Binding Proteins; Guanine; Guanine Nucleotides; Kinetics; Molecular Sequence Data; Mutation; Nucleic Acid Conformation; Operator Regions, Genetic; Purines; Repressor Proteins; Spectrum Analysis, Raman; Temperature; Transcription Factors; Viral Proteins; Viral Regulatory and Accessory Proteins | 1992 |
In vivo footprinting of the human alpha-globin locus upstream regulatory element by guanine and adenine ligation-mediated polymerase chain reaction.
Topics: Adenine; Animals; Base Sequence; Binding Sites; Cell Line; DNA; DNA Fingerprinting; DNA-Binding Proteins; Globins; Guanine; Humans; Hybrid Cells; Methylation; Mice; Molecular Sequence Data; Polymerase Chain Reaction; Promoter Regions, Genetic; Regulatory Sequences, Nucleic Acid | 1992 |
Purine utilisation, de novo synthesis and degradation in mouse preimplantation embryos.
Topics: Adenine; Animals; Azaserine; Blastocyst; Cells, Cultured; Chromatography, High Pressure Liquid; Guanine; Hypoxanthines; Mice; Mice, Inbred Strains; Mycophenolic Acid; Purines; Xanthine; Xanthines | 1992 |
Conformations of Cyclobut-A and Cyclobut-G: structural resemblance to nucleosides and incorporation into double helical DNA.
Topics: Adenine; Antiviral Agents; Deoxyribonucleosides; DNA; Guanine; Models, Molecular; Nucleic Acid Conformation | 1992 |
Transcription efficiency of human apolipoprotein A-I promoter varies with naturally occurring A to G transition.
Topics: Adenine; Apolipoprotein A-I; Base Composition; Base Sequence; DNA; Guanine; Humans; Molecular Sequence Data; Mutation; Promoter Regions, Genetic; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1992 |
Non-planar structure of nitrous bases and non-coplanarity of Watson-Crick pairs.
Topics: Adenine; Aniline Compounds; Base Composition; Cytosine; Formamides; Guanine; Hydrogen Bonding; Models, Molecular; Molecular Conformation | 1992 |
Recognition of a guanine-cytosine base pair by 8-oxoadenine.
Topics: Adenine; Base Composition; Base Sequence; Cytosine; Guanine; Hydrogen Bonding; Models, Structural; Molecular Sequence Data; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Thermodynamics | 1992 |
Rapid c-myc mRNA degradation does not require (A + U)-rich sequences or complete translation of the mRNA.
Topics: Adenine; Animals; Base Composition; Cells, Cultured; Codon; Guanine; Half-Life; Humans; Mutation; Protein Biosynthesis; Proto-Oncogene Mas; Proto-Oncogene Proteins c-myc; Rats; Restriction Mapping; RNA, Messenger; Simian virus 40 | 1991 |
Major alterations in the nucleotide structure of DNA in cancer of the female breast.
Topics: Adenine; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cell Transformation, Neoplastic; Chromatography, Gas; DNA; Female; Guanine; Humans; Hydroxylation; Mass Spectrometry; Pyrimidines | 1991 |
Absorption and metabolism of purines by the lower intestine of the chicken.
Topics: Adenine; Animals; Chickens; Guanine; Hypoxanthine; Hypoxanthines; Intestinal Absorption; Intestinal Mucosa; Intestines; Male; Purines; Uric Acid; Xanthine; Xanthines | 1991 |
Inhibition of avian myeloblastosis virus reverse transcriptase by diphosphates of acyclic phosphonylmethyl nucleotide analogues.
Topics: Adenine; Animals; Antiviral Agents; Avian Myeloblastosis Virus; Chickens; Cytosine; Guanine; Nucleotides; Phosphates; Reverse Transcriptase Inhibitors; Thymidine; Uracil | 1990 |
Acyclic nucleotide analogues: synthesis, antiviral activity and inhibitory effects on some cellular and virus-encoded enzymes in vitro.
Topics: Adenine; Adenosine; Antiviral Agents; Cidofovir; Cytosine; DNA Viruses; Guanine; In Vitro Techniques; Nucleic Acid Synthesis Inhibitors; Nucleotides; Organophosphonates; Organophosphorus Compounds; Purine-Nucleoside Phosphorylase; Reverse Transcriptase Inhibitors; Ribonucleotide Reductases; Structure-Activity Relationship; Tubercidin | 1990 |
The determination of absolute electron affinities of the purines and pyrimidines in DNA and RNA from reversible reduction potentials.
Topics: Adenine; Cytosine; DNA; Guanine; Potentiometry; Purines; Pyrimidines; RNA; Thymine; Uracil | 1991 |
Incorporation of purine ribonucleotides into nucleic acids of rat liver after castration.
Topics: Adenine; Animals; DNA; Guanine; Kinetics; Liver; Male; Nucleic Acids; Orchiectomy; Purine Nucleotides; Rats; Rats, Inbred Strains; RNA; Testis; Testosterone | 1991 |
Purine metabolites and pyrimidine bases in cerebrospinal fluid of children with simple febrile seizures.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Child, Preschool; Cytosine; Female; Guanine; Guanosine; Humans; Hypoxanthine; Hypoxanthines; Infant; Inosine; Inosine Monophosphate; Male; Purines; Pyrimidine Nucleosides; Seizures, Febrile; Thymine; Uracil; Uric Acid; Xanthine; Xanthines | 1991 |
Incidence of Harvey ras oncogene point mutations and their expression in methylbenzylnitrosamine-induced esophageal tumorigenesis.
Topics: Adenine; Animals; Base Sequence; Carcinogens; Codon; Dimethylnitrosamine; Esophageal Neoplasms; Esophagus; Gene Expression Regulation, Neoplastic; Genes, ras; Guanine; Immunohistochemistry; Male; Molecular Sequence Data; Mutation; Oncogene Protein p21(ras); Papilloma; Rats; Rats, Inbred Strains | 1991 |
Specific diagnosis of medium-chain acyl-CoA dehydrogenase (MCAD) deficiency in dried blood spots by a polymerase chain reaction (PCR) assay detecting a point-mutation (G985) in the MCAD gene.
Topics: Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenases; Adenine; Base Sequence; DNA; Guanine; Humans; Lipid Metabolism, Inborn Errors; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Sensitivity and Specificity | 1991 |
DNA polymerase action blocked by adenine adducts induced by 5-hydroxymethylchrysene sulfate.
Topics: Adenine; Base Sequence; Carcinogens; Chromatography, High Pressure Liquid; Chrysenes; DNA; DNA Damage; DNA Polymerase I; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Guanine; Molecular Sequence Data | 1991 |
Inhibitory effect of (S)-HPMPC, (S)-HPMPA, and 2'-nor-cyclic GMP on clinical ocular adenoviral isolates is serotype-dependent in vitro.
Topics: Adenine; Adenovirus Infections, Human; Adenoviruses, Human; Antiviral Agents; Cidofovir; Conjunctivitis, Viral; Cytosine; DNA; Guanine; Humans; Organophosphonates; Organophosphorus Compounds; Serotyping; Tumor Cells, Cultured; Viral Plaque Assay | 1991 |
Synthesis and duplex stability of oligonucleotides containing adenine-guanine analogues.
Topics: Adenine; Base Composition; Base Sequence; DNA; DNA Probes; Genetic Code; Guanine; Molecular Sequence Data; Molecular Structure; Nucleic Acid Heteroduplexes; Oligodeoxyribonucleotides | 1991 |
Effects of purine nucleoside analogues with a cyclobutane ring and erythromycin A oxime derivatives on duck hepatitis B virus replication in vivo and in cell culture and HIV-1 in cell culture.
Topics: Adenine; Animals; Antiviral Agents; Cells, Cultured; Ducks; Erythromycin; Guanine; Hepatitis B Virus, Duck; HIV-1; Virus Replication | 1991 |
Exposure of pancreatic islets to different alkylating agents decreases mitochondrial DNA content but only streptozotocin induces long-lasting functional impairment of B-cells.
Topics: Adenine; Alkylating Agents; Animals; Cytochrome b Group; DNA; Dose-Response Relationship, Drug; Glucagon; Glucose; Guanine; Immunoblotting; Insulin; Islets of Langerhans; Male; Methyl Methanesulfonate; Methylnitrosourea; Mice; Mitochondria; RNA, Messenger; Streptozocin | 1991 |
Measurements of nucleic bases released after gamma irradiation of DNA in solution in air.
Topics: Adenine; Air; Animals; Cytosine; DNA; DNA, Viral; Gamma Rays; Guanine; Male; Salmon; Simian virus 40; Solutions; Spermatozoa; Thymine; Water | 1991 |
Thermodynamics of DNA duplexes with adjacent G.A mismatches.
Topics: Adenine; Base Composition; Base Sequence; DNA; Guanine; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Nucleic Acid Heteroduplexes; Oligonucleotides; Temperature; Thermodynamics | 1991 |
Tandem mass spectrometric approaches for determining exposure to alkylating agents.
Topics: Adenine; Alkylating Agents; Environmental Monitoring; Guanine; Humans; Mass Spectrometry | 1991 |
Comparison of urinary nitrate, N-nitrosoproline, 7-methylguanine and 3-methyladenine levels in a human population at risk for gastric cancer.
Topics: Adenine; Guanine; Humans; Nitrates; Nitrosamines; Risk; Stomach Neoplasms | 1991 |
Cloning and expression in Escherichia coli of a human cDNA encoding the DNA repair protein N-methylpurine-DNA glycosylase.
Topics: Adenine; Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Blotting, Southern; Cloning, Molecular; DNA; DNA Glycosylases; DNA Repair; Escherichia coli; Genes, Bacterial; Guanine; HeLa Cells; Humans; Molecular Sequence Data; N-Glycosyl Hydrolases; Rats; Restriction Mapping; RNA, Messenger; Sequence Homology, Nucleic Acid | 1991 |
Transforming activity of a synthetic c-Ha-ras gene containing O6-methylguanine in codon 12.
Topics: 3T3 Cells; Adenine; Amino Acid Sequence; Animals; Base Sequence; Cell Transformation, Neoplastic; Codon; Genes, ras; Genes, Synthetic; Genetic Vectors; Guanine; Humans; Mice; Molecular Sequence Data; Mutagenesis, Insertional; Mutation; Oligonucleotides; Transfection | 1991 |
The vinyl chloride DNA derivative N2,3-ethenoguanine produces G----A transitions in Escherichia coli.
Topics: Adenine; Base Composition; Base Sequence; DNA Polymerase II; DNA Replication; DNA, Bacterial; Escherichia coli; Guanine; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutagens; Oligodeoxyribonucleotides; Uracil; Vinyl Chloride | 1991 |
Detection of the G to A mitochondrial DNA mutation at position 11778 in German families with Leber's hereditary optic neuropathy.
Topics: Adenine; Base Sequence; DNA Mutational Analysis; DNA, Mitochondrial; Female; Germany; Guanine; Humans; Male; Molecular Sequence Data; Mutation; Optic Atrophies, Hereditary; Pedigree; Polymerase Chain Reaction | 1991 |
A novel mechanism of mycophenolic acid resistance in the protozoan parasite Tritrichomonas foetus.
Topics: Adenine; Animals; Cloning, Molecular; Drug Resistance; Guanine; Guanine Nucleotides; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; IMP Dehydrogenase; Ketone Oxidoreductases; Mutation; Mycophenolic Acid; Tritrichomonas; Xanthine; Xanthines | 1990 |
NMR and molecular modeling evidence for a G.A mismatch base pair in a purine-rich DNA duplex.
Topics: Adenine; Base Composition; Base Sequence; DNA; Guanine; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Oligodeoxyribonucleotides | 1991 |
Transcription by eucaryotic and procaryotic RNA polymerases of DNA modified at a d(GG) or a d(AG) site by the antitumor drug cis-diamminedichloroplatinum(II).
Topics: Adenine; Base Sequence; Cisplatin; DNA; DNA-Directed RNA Polymerases; Escherichia coli; Guanine; Molecular Sequence Data; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Templates, Genetic; Transcription, Genetic; Triticum | 1991 |
Urinary excretion of nitrate, N-nitrosoproline, 3-methyladenine, and 7-methylguanine in a Colombian population at high risk for stomach cancer.
Topics: Adenine; Colombia; Guanine; Humans; Nitrates; Nitrosamines; Regression Analysis; Risk Factors; Stomach Neoplasms | 1991 |
Formation of DNA triplexes accounts for arrests of DNA synthesis at d(TC)n and d(GA)n tracts.
Topics: Adenine; Base Sequence; DNA Replication; DNA-Binding Proteins; DNA-Directed DNA Polymerase; DNA, Single-Stranded; Escherichia coli; Guanine; Hydrogen Bonding; Kinetics; Models, Structural; Molecular Sequence Data; Nucleic Acid Conformation; Polydeoxyribonucleotides; Polymerase Chain Reaction; Templates, Genetic; Thermodynamics | 1991 |
Molecular defect of a phosphoglycerate kinase variant (PGK-Matsue) associated with hemolytic anemia: Leu----Pro substitution caused by T/A----C/G transition in exon 3.
Topics: Adenine; Anemia, Hemolytic; Base Sequence; Cytosine; DNA; Exons; Female; Guanine; Humans; Leucine; Male; Molecular Sequence Data; Mutation; Phosphoglycerate Kinase; Proline; Thymine | 1991 |
The effect of nutritional state and allopurinol on nucleotide formation in enterocytes from the guinea pig small intestine.
Topics: Adenine; Adenine Phosphoribosyltransferase; Allopurinol; Animals; Biological Transport; Fasting; Food; Guanine; Guanosine; Guinea Pigs; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Inosine; Inosine Monophosphate; Intestinal Mucosa; Intestine, Small; Male; Nucleotides; Xanthine Oxidase | 1991 |
DNA binding of methyl iodide in male and female F344 rats.
Topics: Adenine; Administration, Inhalation; Administration, Oral; Animals; Carbon Radioisotopes; Chromatography, High Pressure Liquid; DNA; Female; Gastric Mucosa; Guanine; Hydrocarbons, Iodinated; Hydrolysis; Liver; Lung; Male; Purines; Rats; Rats, Inbred F344 | 1991 |
G to A polymorphism in the second exon of the BCL2 gene.
Topics: Adenine; Base Sequence; Chromosomes, Human, Pair 18; Exons; Female; Guanine; Humans; Male; Molecular Sequence Data; Oligodeoxyribonucleotides; Pedigree; Polymerase Chain Reaction; Polymorphism, Genetic; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogenes | 1991 |
Diagrammatic representation of the distribution of DNA bases and its applications.
Topics: Adenine; Animals; Bacteria; Base Composition; Biological Evolution; Codon; Cytosine; DNA; Genetic Variation; Guanine; Humans; Linear Models; Mathematics; Plants; RNA, Messenger; Thymine; Uracil | 1991 |
The N2-guanine adduct but not the C8-guanine or N6-adenine adducts formed by 4-nitroquinoline 1-oxide blocks the 3'-5' exonuclease action of T4 DNA polymerase.
Topics: 4-Nitroquinoline-1-oxide; Adenine; Aminoquinolines; Animals; Cattle; DNA; DNA-Directed DNA Polymerase; Exodeoxyribonuclease V; Exodeoxyribonucleases; Guanine; Hydrolysis; Nitroquinolines; T-Phages; Ultraviolet Rays | 1990 |
Induction of specific frameshift and base substitution events by benzo[a]pyrene diol epoxide in excision-repair-deficient Escherichia coli.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adenine; Base Composition; Base Sequence; Cytosine; Dihydroxydihydrobenzopyrenes; DNA Damage; DNA Repair; DNA, Bacterial; Escherichia coli; Guanine; Molecular Sequence Data; Mutation; Thymine | 1990 |
Myoclonic epilepsy and ragged-red fiber disease (MERRF) is associated with a mitochondrial DNA tRNA(Lys) mutation.
Topics: Adenine; Base Sequence; DNA, Mitochondrial; Epilepsies, Myoclonic; Female; Guanine; Humans; Male; Mitochondria, Muscle; Molecular Sequence Data; Mutation; Nucleic Acid Conformation; Oligonucleotide Probes; Pedigree; RNA, Transfer, Amino Acid-Specific; RNA, Transfer, Lys | 1990 |
Methylthioadenosine serves as a single carbon source to the folate co-enzyme pool in rat bone marrow cells.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Bone Marrow; Carbon; Deoxyadenosines; Folic Acid; Formates; Glycine; Guanine; Male; Methionine; Methionine Adenosyltransferase; Oxidation-Reduction; Rats; Rats, Inbred Strains; Serine; Thionucleosides | 1990 |
Aneuploidy induction by alkylated bases and nucleosides in mammalian cells.
Topics: Adenine; Adenosine Deaminase; Alkylation; Aneuploidy; Animals; Cells, Cultured; Cricetinae; Cricetulus; DNA Damage; Guanine; Guanosine; Humans; Hypoxanthine Phosphoribosyltransferase; Methyltransferases; Models, Biological; Nucleosides; O(6)-Methylguanine-DNA Methyltransferase; Purine-Nucleoside Phosphorylase; Structure-Activity Relationship | 1990 |
A "G" to "A" mutation at position -1 of a 5' splice site in a late infantile form of Tay-Sachs disease.
Topics: Adenine; Base Sequence; beta-N-Acetylhexosaminidases; Blotting, Northern; Cells, Cultured; DNA; Exons; Fibroblasts; Guanine; Humans; Infant; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Polymerase Chain Reaction; Restriction Mapping; RNA Splicing; Tay-Sachs Disease; Transcription, Genetic | 1990 |
The GC-selective ligand mithramycin alters the structure of (AT)n sequences flanking its binding sites.
Topics: Adenine; Base Composition; Base Sequence; Cloning, Molecular; Cytosine; Deoxyribonucleases; DNA; Guanine; Molecular Sequence Data; Nucleotide Mapping; Plasmids; Plicamycin; Thymine | 1990 |
Specific A/G-to-C.G mismatch repair in Salmonella typhimurium LT2 requires the mutB gene product.
Topics: Adenine; Bacterial Proteins; Base Composition; Base Sequence; Cytosine; DNA Repair; DNA Transposable Elements; DNA-Binding Proteins; Escherichia coli; Genotype; Guanine; Molecular Sequence Data; Mutation; N-Glycosyl Hydrolases; Oligonucleotide Probes; Salmonella typhimurium; Transduction, Genetic | 1990 |
Synthesis and antiviral activity of (S)-9-[4-hydroxy-3-(phosphonomethoxy)butyl]guanine.
Topics: Adenine; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; Guanine; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Viral Plaque Assay | 1990 |
A method for determining the relative effect of ligands on A-T and G-C base pairs in DNA: applications to metal ions, protons and two amino acids.
Topics: Adenine; Aminobutyrates; Base Composition; beta-Alanine; Calorimetry; Cytosine; DNA; Guanine; Ligands; Metals; Nucleic Acid Denaturation; Protons; Thymine | 1990 |
DNA alkylations and mutation after exposure to ethyl methanesulphonate in mammalian cell lines routinely used in mutagenicity testing.
Topics: Adenine; Alkylation; Animals; Cell Line; Chromatography, High Pressure Liquid; DNA; DNA Damage; Ethyl Methanesulfonate; Guanine; Humans; Mutagenicity Tests; Mutagens; Mutation; Tritium | 1990 |
Structural and thermodynamic studies on the adenine.guanine mismatch in B-DNA.
Topics: Adenine; Base Composition; Base Sequence; DNA; Guanine; Hydrogen Bonding; Hydrogen-Ion Concentration; Molecular Sequence Data; Molecular Structure; Nucleic Acid Conformation; Solvents; Thermodynamics; X-Ray Diffraction | 1990 |
Base modifications in plasmid DNA caused by potassium permanganate.
Topics: Adenine; Cytosine; DNA Damage; Escherichia coli; Gas Chromatography-Mass Spectrometry; Guanine; Mutation; Plasmids; Potassium Permanganate; Thymine | 1990 |
Chlamydomonas telomere sequences are A+T-rich but contain three consecutive G-C base pairs.
Topics: Adenine; Base Composition; Chlamydomonas; Chromosomes; Cloning, Molecular; Cytosine; Escherichia coli; Guanine; Molecular Sequence Data; Repetitive Sequences, Nucleic Acid; Sequence Homology, Nucleic Acid; Thymine | 1990 |
Cloning and expression in Escherichia coli of a gene for an alkylbase DNA glycosylase from Saccharomyces cerevisiae; a homologue to the bacterial alkA gene.
Topics: Adenine; Amino Acid Sequence; Base Sequence; Cloning, Molecular; DNA Glycosylases; DNA Repair; Drug Resistance; Escherichia coli; Gene Expression; Genes, Bacterial; Genes, Fungal; Guanine; Methyl Methanesulfonate; Molecular Sequence Data; N-Glycosyl Hydrolases; Open Reading Frames; Restriction Mapping; Saccharomyces cerevisiae; Sequence Homology, Nucleic Acid | 1990 |
The identification and quantitation of alkylated nucleobases by high-performance liquid chromatography with UV photodiode array detection.
Topics: Adenine; Alkylation; Chromatography, High Pressure Liquid; Guanine; Reference Standards; Spectrophotometry, Ultraviolet; Thymine; Uracil | 1990 |
Note on the preference of aliphatic epoxides for the N-7 position of guanine in DNA.
Topics: Adenine; Alkylating Agents; Alkylation; DNA; Epoxy Compounds; Ethylene Oxide; Guanine; Hydrogen Bonding | 1990 |
Structure and autoregulation of the c-rel promoter.
Topics: Adenine; Animals; Base Sequence; Chickens; Chromosome Deletion; Cloning, Molecular; Cytosine; DNA; Exons; Guanine; Homeostasis; Luciferases; Molecular Sequence Data; Promoter Regions, Genetic; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-rel; RNA, Messenger; Thymine; Transcription, Genetic | 1990 |
An intron mutation in the human alpha 1(I) collagen gene alters the efficiency of pre-mRNA splicing and is associated with osteogenesis imperfecta type II.
Topics: Adenine; Base Sequence; Collagen; Cyanogen Bromide; Genes; Guanine; Humans; Introns; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Osteogenesis Imperfecta; Peptide Mapping; Polymerase Chain Reaction; Reference Values; Restriction Mapping; RNA Precursors; RNA Splicing | 1990 |
Atomic charges for DNA constituents derived from single-crystal X-ray diffraction data.
Topics: Adenine; Cytosine; Deoxyribose; DNA; Guanine; Models, Molecular; Nucleic Acid Conformation; Thymine; X-Ray Diffraction | 1990 |
Prominent stacking interaction with aromatic amino acid by N-quarternization of nucleic acid base: X-ray crystallographic characteristics and biological implications.
Topics: Adenine; Amino Acids; Chemical Phenomena; Chemistry; Crystallization; Cytidine Monophosphate; Cytosine; Cytosine Nucleotides; Guanine; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Nucleic Acid Conformation; Tryptamines; X-Ray Diffraction | 1990 |
Cyclobut-A and cyclobut-G, carbocyclic oxetanocin analogs that inhibit the replication of human immunodeficiency virus in T cells and monocytes and macrophages in vitro.
Topics: Adenine; Antiviral Agents; Blotting, Southern; Cell Line; Cytopathogenic Effect, Viral; Guanine; HIV-1; HIV-2; Humans; Macrophage Activation; Macrophages; Mitogens; Monocytes; Nucleosides; T-Lymphocytes; Virus Replication | 1990 |
Cyclobut-A and cyclobut-G: broad-spectrum antiviral agents with potential utility for the therapy of AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adenine; Animals; Antiviral Agents; Guanine; Herpesviridae; HIV; Humans; Mice; Microbial Sensitivity Tests | 1990 |
Studies on the energy metabolism of opossum (Didelphis virginiana) erythrocytes: V. Utilization of hypoxanthine for the synthesis of adenine and guanine nucleotides in vitro.
Topics: Adenine; Adenosine Triphosphate; Animals; Energy Metabolism; Erythrocytes; Guanine; Guanosine Triphosphate; Hemoglobins; Hypoxanthines; Nucleotides; Opossums; Oxidation-Reduction; Tritium | 1990 |
Identical G+1 to A mutations in three different introns of the type III procollagen gene (COL3A1) produce different patterns of RNA splicing in three variants of Ehlers-Danlos syndrome. IV. An explanation for exon skipping some mutations and not others.
Topics: Adenine; Adult; Calorimetry; Cloning, Molecular; Ehlers-Danlos Syndrome; Exons; Female; Genes; Genetic Variation; Guanine; Humans; Introns; Male; Mutation; Polymerase Chain Reaction; Pregnancy; Procollagen; RNA Probes; RNA Splicing; RNA, Small Nuclear; Templates, Genetic | 1990 |
The poly (purine) poly (pyrimidine) sequence in the 5' end of the thyroglobulin gene used as a probe, identifies a DNA fingerprint in man.
Topics: Adenine; Base Sequence; DNA; DNA Probes; Genes; Guanine; Humans; Molecular Sequence Data; Nucleotide Mapping; Repetitive Sequences, Nucleic Acid; Thyroglobulin | 1990 |
Crystal structure and sequence-dependent conformation of the A.G mispaired oligonucleotide d(CGCAAGCTGGCG).
Topics: Adenine; Base Composition; Base Sequence; Crystallization; Guanine; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Oligodeoxyribonucleotides | 1990 |
The conserved dinucleotide AG of the 3' splice site may be recognized twice during in vitro splicing of mammalian mRNA precursors.
Topics: Adenine; Base Sequence; Exons; Globins; Guanine; Humans; In Vitro Techniques; Introns; Molecular Sequence Data; Mutation; RNA Precursors; RNA Splicing; RNA, Messenger; Thalassemia | 1990 |
Partial purification of an adenine-dependent serum factor which retards the reactivation of lens epithelial cells in primary culture by inhibiting protein synthesis and cell spreading.
Topics: Adenine; Animals; Cattle; Cell Adhesion; Cells, Cultured; Drug Synergism; Epithelium; Eye Proteins; Growth Inhibitors; Guanine; Hypoxanthine; Hypoxanthines; Lens, Crystalline; Protein Synthesis Inhibitors | 1990 |
Purine nucleotide metabolism in resident and activated rat macrophages in vitro.
Topics: Adenine; Adenosine; Animals; Cells, Cultured; Guanine; Guanosine; Hypoxanthine; Hypoxanthines; Inosine; Macrophage Activation; Macrophages; Pentosephosphates; Phosphoribosyl Pyrophosphate; Purine Nucleotides; Rats; Thioglycolates | 1985 |
Serine metabolism in rat embryos undergoing organogenesis.
Topics: Adenine; Amino Acids; Animals; DNA; Embryo, Mammalian; Guanine; Rats; RNA; Serine; Thymine; Yolk Sac | 1985 |
Nomenclature for incompletely specified bases in nucleic acid sequences. Recommendations 1984. Nomenclature Committee of the International Union of Biochemistry (NC-IUB).
Topics: Adenine; Base Sequence; Codon; Cytosine; DNA; DNA Restriction Enzymes; Guanine; Nucleotides; Protein Biosynthesis; RNA; Substrate Specificity; Terminology as Topic; Thymine | 1986 |
Determination of assay parameters for RNA analysis in bacterial and duodenal samples by spectrophotometry. Influence of sample treatment and preservation.
Topics: Adenine; Animals; Bacteria; Chromatography, High Pressure Liquid; Diet; Duodenum; Guanine; Male; RNA; Rumen; Sheep; Sulfur Radioisotopes | 1985 |
Isolation and fractionation of CHO chromosomes in aqueous two phase systems using charged polymers and base specific macroligands.
Topics: Adenine; Animals; Base Composition; Cell Fractionation; Cell Line; Cell Nucleus; Chromosomes; Cricetinae; Cytosine; Dextrans; DNA; Female; Guanine; Ligands; Metaphase; Mitotic Index; Ovary; Polyethylene Glycols; Thymidine | 1986 |
Growth of Lactobacillus bulgaricus in milk. 2. Characteristics of purine nucleotides, pyrimidine nucleotides, and nucleic acid synthesis.
Topics: Adenine; Adenosine Monophosphate; Animals; Cattle; DNA, Bacterial; Guanine; Guanosine Monophosphate; In Vitro Techniques; Lactobacillus; Milk; Orotic Acid; Purine Nucleotides; RNA, Bacterial | 1986 |
Vacuum ultraviolet circular dichroism as an indicator of helical handedness in nucleic acids.
Topics: Adenine; Circular Dichroism; Cytosine; DNA; Guanine; Nucleic Acid Conformation; RNA; Spectrophotometry, Ultraviolet; Thymine; Uracil | 1986 |
Glyphosate catabolism by Pseudomonas sp. strain PG2982.
Topics: Adenine; Bacterial Proteins; Formaldehyde; Formates; Glycine; Glyphosate; Guanine; Methionine; Oxidoreductases, N-Demethylating; Pseudomonas; Sarcosine; Sarcosine Oxidase; Serine | 1986 |
The role of cyclic base adducts in vinyl-chloride-induced carcinogenesis: studies on nucleic acid alkylation in vivo.
Topics: Acetaldehyde; Adenine; Alkylation; Animals; Carcinogens; Cytosine; DNA; DNA Damage; Ethylene Oxide; Guanine; Microsomes, Liver; Rats; RNA; Vinyl Chloride; Vinyl Compounds | 1986 |
Antigiardial activity of guanine arabinoside. Mechanism studies.
Topics: Adenine; Adenosine; Animals; Arabinonucleotides; Deoxyadenosines; Deoxyguanosine; DNA Replication; Giardia; Guanine; Guanosine; Guanosine Triphosphate; Protein Biosynthesis; RNA | 1987 |
The Greek A gamma beta+-HPFH observed in a large black family.
Topics: Adenine; Base Sequence; Black People; Chromatography, High Pressure Liquid; Chromosome Mapping; DNA Restriction Enzymes; Female; Fetal Hemoglobin; Globins; Guanine; Haploidy; Hemoglobin A2; Hemoglobinopathies; Humans; Male; Pedigree | 1987 |
Purine nucleotide metabolism in phytohemagglutinin-induced human T lymphocytes.
Topics: Adenine; Adenine Nucleotides; DNA; Guanine; Guanine Nucleotides; Humans; Hypoxanthine; Hypoxanthines; Inosine Monophosphate; Pentosephosphates; Phosphoribosyl Pyrophosphate; Phytohemagglutinins; Purine Nucleotides; RNA; T-Lymphocytes | 1987 |
Interaction of a putative repressor protein with an extended control region of the Bacillus subtilis pur operon.
Topics: Adenine; Bacillus subtilis; Base Sequence; Binding Sites; Chromatography, Ion Exchange; Deoxyribonuclease I; DNA Topoisomerases, Type II; DNA, Bacterial; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation; Guanine; Molecular Sequence Data; Operon; Promoter Regions, Genetic; Purine Nucleotides; Repressor Proteins; Transcription Factors; Transcription, Genetic | 1989 |
Improved chemistry for oligodeoxyribonucleotide synthesis substantially improves restriction enzyme cleavage of a synthetic 35mer.
Topics: Adenine; Base Composition; Cloning, Molecular; DNA; DNA Modification Methylases; DNA Restriction Enzymes; Guanine; Oligodeoxyribonucleotides; Organophosphorus Compounds; Piperidines; Restriction Mapping; Substrate Specificity; Thymine | 1989 |
Efficacy of oxetanocin G against herpes simplex virus type 2 and murine cytomegalovirus infections in mice.
Topics: Acyclovir; Adenine; Animals; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Disease Models, Animal; Ganciclovir; Guanine; Herpes Simplex; Male; Mice; Mice, Inbred ICR; Prodrugs | 1989 |
Recognition of thymine adenine.base pairs by guanine in a pyrimidine triple helix motif.
Topics: Adenine; Base Sequence; DNA; DNA, Viral; Guanine; HIV; Hydrogen Bonding; Models, Structural; Molecular Sequence Data; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Simian virus 40; Thymine | 1989 |
Matrix-isolation of H-induced free radicals from purines in acidic glasses.
Topics: Adenine; Electron Spin Resonance Spectroscopy; Free Radicals; Glass; Guanine; Hydrogen; Hypoxanthine; Hypoxanthines; Purines; Sulfuric Acids; Xanthine; Xanthines | 1989 |
Ultraviolet difference spectral studies in the gamma radiolysis of DNA and model compounds. I. Aqueous solutions of DNA bases.
Topics: Adenine; Cobalt Radioisotopes; Cytosine; Gamma Rays; Guanine; Solutions; Spectrophotometry, Ultraviolet; Thymine; Water | 1989 |
Selection of an oral prodrug (BRL 42810; famciclovir) for the antiherpesvirus agent BRL 39123 [9-(4-hydroxy-3-hydroxymethylbut-l-yl)guanine; penciclovir].
Topics: 2-Aminopurine; Acyclovir; Adenine; Animals; Antiviral Agents; Bile; Biological Availability; Chromatography, High Pressure Liquid; Duodenum; Famciclovir; Guanine; Humans; In Vitro Techniques; Intestinal Mucosa; Liver; Male; Prodrugs; Rats; Tissue Distribution | 1989 |
Conformation of DNA modified at a d(GG) or a d(AG) site by the antitumor drug cis-diamminedichloroplatinum(II).
Topics: Adenine; Base Sequence; Cisplatin; DNA; DNA Damage; Electrophoresis; Guanine; Molecular Sequence Data; Nucleic Acid Conformation; Nucleic Acid Heteroduplexes; Oligonucleotide Probes | 1989 |
Expression of a novel high affinity purine base transport system in mutant mouse S49 cells does not require a functional nucleoside transporter.
Topics: Adenine; Animals; Biological Transport; Clone Cells; Dipyridamole; Dose-Response Relationship, Drug; Gene Expression; Guanine; Hybridization, Genetic; Hypoxanthine; Hypoxanthines; Inosine; Lymphoma; Mice; Mice, Inbred BALB C; Mutation; Phenotype; T-Lymphocytes; Thioinosine; Tumor Cells, Cultured | 1989 |
[The pool of free purine and pyrimidine nucleosides and bases in the thymocytes, and splenic T- and B-lymphocytes of C3HA mice during the growth of solid hepatoma 22a].
Topics: Adenine; Adenosine; Animals; B-Lymphocytes; Deoxycytidine; DNA, Neoplasm; Guanine; Hypoxanthine; Hypoxanthines; Inosine; Liver Neoplasms, Experimental; Mice; Mice, Inbred C3H; Purine Nucleosides; Pyrimidine Nucleosides; Spleen; T-Lymphocytes; Thymus Gland; Time Factors; Xanthine; Xanthines | 1989 |
Mutagenic specificity of a potent carcinogen, benzo[c]phenanthrene (4R,3S)-dihydrodiol (2S,1R)-epoxide, which reacts with adenine and guanine in DNA.
Topics: Adenine; Base Composition; Base Sequence; Carcinogens; DNA, Bacterial; Escherichia coli; Genes, Bacterial; Genetic Vectors; Guanine; Molecular Sequence Data; Mutagens; Nucleic Acid Conformation | 1989 |
A specific role of MutT protein: to prevent dG.dA mispairing in DNA replication.
Topics: Adenine; Bacterial Proteins; Base Composition; Deoxyguanine Nucleotides; DNA Replication; Escherichia coli; Escherichia coli Proteins; Genes; Genes, Bacterial; Guanine; Kinetics; Mutation; Phosphoric Monoester Hydrolases; Pyrophosphatases | 1989 |
Escherichia coli mutY gene encodes an adenine glycosylase active on G-A mispairs.
Topics: Adenine; Base Composition; DNA Glycosylases; DNA Repair; DNA, Bacterial; Escherichia coli; Genes, Bacterial; Guanine; N-Glycosyl Hydrolases | 1989 |
N-ethyl-N-nitrosourea induces A:T to C:G transversion mutations as well as transition mutations in SOS-induced Escherichia coli.
Topics: Adenine; Base Composition; Base Sequence; Chromosome Deletion; Cytosine; DNA Damage; DNA Repair; DNA, Bacterial; Escherichia coli; Ethylnitrosourea; Genes, Bacterial; Guanine; Molecular Sequence Data; Mutation; SOS Response, Genetics; Thymine | 1989 |
Electrical conduction in some nucleic acid base complexes with acridine orange dye: study of localized levels.
Topics: Acridine Orange; Adenine; Electric Conductivity; Guanine; Models, Chemical; Nucleic Acids; Semiconductors; Thymine; Uracil | 1989 |
Purine base transport in wild-type and mycophenolic acid-resistant Tritrichomonas foetus.
Topics: Adenine; Allopurinol; Animals; Biological Transport; Diffusion; Drug Resistance; Guanine; Hypoxanthines; Kinetics; Mycophenolic Acid; Purine Nucleosides; Purines; Tritrichomonas; Xanthines | 1989 |
Different patterns of G/T and A/C mismatch repair in simian cells correspond to the specificity of a mismatch binding protein isolated from simian and HeLa cells.
Topics: Adenine; Animals; Base Composition; Cells, Cultured; Chlorocebus aethiops; Cytosine; DNA Repair; DNA-Binding Proteins; Guanine; HeLa Cells; Humans; Thymine | 1989 |
Prodrugs of the selective antiherpesvirus agent 9-[4-hydroxy-3-(hydroxymethyl)but-1-yl]guanine (BRL 39123) with improved gastrointestinal absorption properties.
Topics: 2-Aminopurine; Acyclovir; Adenine; Animals; Antiviral Agents; Chemical Phenomena; Chemistry; Famciclovir; Guanine; Intestinal Absorption; Mice; Prodrugs | 1989 |
Crystal structure and stability of a DNA duplex containing A(anti).G(syn) base-pairs.
Topics: Adenine; Base Composition; Base Sequence; Guanine; Molecular Sequence Data; Nucleotides; X-Ray Diffraction | 1989 |
Repair of N-methylpurines in specific DNA sequences in Chinese hamster ovary cells: absence of strand specificity in the dihydrofolate reductase gene.
Topics: Adenine; Animals; Cell Line; Cricetinae; Deoxyribonucleases, Type II Site-Specific; Dimethyl Sulfoxide; DNA; DNA Damage; DNA Probes; DNA Repair; Electrophoresis, Agar Gel; Exons; Guanine; Hot Temperature; Hydrolysis; Nucleic Acid Hybridization; RNA Probes; Sulfuric Acid Esters; Tetrahydrofolate Dehydrogenase; Transcription, Genetic | 1989 |
A point mutation G----A in exon 12 of the porphobilinogen deaminase gene results in exon skipping and is responsible for acute intermittent porphyria.
Topics: Acute Disease; Adenine; Amino Acid Sequence; Ammonia-Lyases; B-Lymphocytes; Base Sequence; Calorimetry; Cells, Cultured; Codon; DNA; Exons; Gene Amplification; Genes; Guanine; Humans; Hydroxymethylbilane Synthase; Introns; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Porphyrias | 1989 |
Selective inhibition of human cytomegalovirus replication by a novel nucleoside, oxetanocin G.
Topics: Adenine; Antiviral Agents; Cell Cycle; Cytomegalovirus; DNA, Viral; Fibroblasts; Guanine; Humans; Simplexvirus; Viral Proteins; Virus Replication | 1988 |
Purine salvage in Entamoeba histolytica.
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Chromatography, High Pressure Liquid; Entamoeba histolytica; Guanine; Guanine Nucleotides; Guanosine; Inosine Monophosphate; Kinetics; Ribose | 1985 |
Enzyme-pattern-targeted chemotherapy with tiazofurin and allopurinol in human leukemia.
Topics: Adenine; Aged; Allopurinol; Animals; Drug Evaluation; Female; Guanine; Guanosine Triphosphate; Humans; IMP Dehydrogenase; Ketone Oxidoreductases; Leukemia; Leukemia, Myeloid, Acute; Liver Neoplasms, Experimental; Male; Middle Aged; Rats; Ribavirin; Ribonucleosides; Tumor Cells, Cultured | 1988 |
Embryotoxicity induced by alkylating agents. Some methodological aspects of DNA alkylation studies in murine embryos using ethylmethanesulfonate.
Topics: Adenine; Alkylation; Animals; DNA; Embryo, Mammalian; Ethyl Methanesulfonate; Female; Guanine; Liver; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred Strains; Pregnancy; Spectrophotometry, Infrared; Structure-Activity Relationship | 1987 |
Some mismatch repair activities in Escherichia coli.
Topics: Adenine; Bacteriophage lambda; Base Sequence; Chromosome Mapping; Cytidine; DNA Repair; Escherichia coli; Guanine; Methylation; Mutation; Phenotype; Recombination, Genetic | 1988 |
The effects of base analogue substitutions on the cleavage by the EcoRI restriction endonuclease of octadeoxyribonucleotides containing modified EcoRI recognition sequences.
Topics: Adenine; Base Sequence; Binding Sites; Cytosine; Deoxyribonuclease EcoRI; DNA Restriction Enzymes; Guanine; Hydrolysis; Hypoxanthine; Hypoxanthines; Kinetics; Methylation; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Structure-Activity Relationship; Temperature; Thymine | 1986 |
The effects of base analogue substitutions on the methylation by the EcoRI modification methylase of octadeoxyribonucleotides containing modified EcoRI recognition sequences.
Topics: Adenine; Base Sequence; Binding Sites; Cytosine; Deoxyribonuclease EcoRI; DNA; DNA Restriction Enzymes; Guanine; Kinetics; Methylation; Methyltransferases; Oligodeoxyribonucleotides; Site-Specific DNA-Methyltransferase (Adenine-Specific); Structure-Activity Relationship; Thymine | 1986 |
Kinetics of the proton-deuteron exchange at position H8 of adenine and guanine in DNA.
Topics: Adenine; Deuterium; DNA; Guanine; Kinetics; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Protons; Sodium Chloride; Temperature | 1986 |
Synthesis and biological evaluation of acyclic neplanocin analogues.
Topics: Adenine; Animals; Antineoplastic Agents; Antiviral Agents; Drug Evaluation, Preclinical; Guanine; Indicators and Reagents; Leukemia P388; Magnetic Resonance Spectroscopy; Mice; Simplexvirus; Spectrophotometry, Infrared; Structure-Activity Relationship | 1987 |
Radiation-induced DNA damage and its repair.
Topics: Adenine; Cytosine; DNA; DNA Damage; DNA Glycosylases; DNA Repair; Endonucleases; Escherichia coli; Exonucleases; Gamma Rays; Guanine; N-Glycosyl Hydrolases; Superoxides; Thymine | 1987 |
Escherichia coli mutY gene product is required for specific A-G----C.G mismatch correction.
Topics: Adenine; Base Composition; Cytosine; DNA Repair; Escherichia coli; Genes, Bacterial; Genotype; Guanine; Mutation; Phenotype | 1988 |
Analysis of the recognition mechanism involved in the EcoRV catalyzed cleavage of DNA using modified oligodeoxynucleotides.
Topics: Adenine; Base Sequence; Catalysis; Cytosine; Deoxyribonucleases, Type II Site-Specific; DNA; Escherichia coli; Guanine; Kinetics; Molecular Sequence Data; Nucleic Acid Conformation; Oligonucleotide Probes; Thymine | 1988 |
Adenosine analog metabolism in Giardia lamblia. Implications for chemotherapy.
Topics: Adenine; Adenosine; Formycins; Giardia; Giardiasis; Guanine; Phosphorylation; Purine-Nucleoside Phosphorylase; Tubercidin | 1986 |
Gene-enzyme relationships of the purine biosynthetic pathway in Bacillus subtilis.
Topics: Adenine; Bacillus subtilis; Bacterial Proteins; Chromosome Mapping; Cloning, Molecular; Genes, Bacterial; Genetic Linkage; Guanine; Hypoxanthines; Mutation; Purines; Transduction, Genetic | 1988 |
Particular behavior of the adenine and guanine ring-breathing modes upon the DNA conformational transitions.
Topics: Adenine; Chemical Phenomena; Chemistry; DNA; Guanine; Nucleic Acid Conformation; Spectrum Analysis, Raman; Vibration | 1988 |
Universal rule for coding sequence construction: TA/CG deficiency-TG/CT excess.
Topics: Adenine; Amino Acid Sequence; Animals; Base Composition; Base Sequence; Cytidine; Glycoproteins; Guanine; Histones; Humans; Phosphoglycerate Kinase; Receptors, Estrogen; Thymidine; Trout | 1988 |
Ruthenium(III) ion complexes with nucleic acid bases and nucleosides.
Topics: Adenine; Adenosine; Cytosine; Guanine; Guanosine; Inosine; Ruthenium; Ruthenium Compounds; Spectrophotometry; Spectrophotometry, Infrared | 1988 |
Enucleation of phagocytic cells with adenine, guanine, and their nucleosides in combination with centrifugation.
Topics: Adenine; Animals; Cell Nucleus; Centrifugation; Cytochalasin B; Female; Guanine; Macrophages; Mice; Mice, Inbred ICR; Mice, Inbred Strains; Microscopy, Electron, Scanning; Nucleosides; Phagocytes | 1988 |
The role of structural water in the formation of nucleotide mispairs.
Topics: Adenine; Base Composition; Computer Simulation; Cytosine; DNA Damage; DNA Replication; Guanine; Magnetic Resonance Spectroscopy; Mutation; Nucleic Acid Conformation; Thermodynamics; Uracil; Water | 1987 |
The AGG codon is translated slowly in E. coli even at very low expression levels.
Topics: Adenine; Base Sequence; Cloning, Molecular; Codon; Escherichia coli; Gene Expression Regulation; Guanine; Isopropyl Thiogalactoside; Lac Operon; Molecular Sequence Data; Protein Biosynthesis; RNA, Messenger | 1988 |
Uptake of purine bases by Trypanosoma cruzi culture epimastigotes.
Topics: Adenine; Animals; Culture Media; Guanine; Hypoxanthines; Pentosyltransferases; Purines; Trypanosoma cruzi | 1986 |
Purine base uptake in Trypanosoma cruzi: adaptations and effects of inhibitors.
Topics: Adenine; Animals; Cell Membrane; Guanine; Hypoxanthines; Pentosyltransferases; Purines; Trypanosoma cruzi | 1987 |
Purine nucleobase transport in human erythrocytes. Reinvestigation with a novel "inhibitor-stop" assay.
Topics: Adenine; Biological Transport; Erythrocytes; Guanine; Humans; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Kinetics; Papaverine | 1988 |
Acyclovir transport into human erythrocytes.
Topics: Acyclovir; Adenine; Biological Transport; Carbon Radioisotopes; Erythrocytes; Guanine; Humans; Hypoxanthine; Hypoxanthines; Idoxuridine; Iodine Radioisotopes; Kinetics; Nucleosides; Purines; Pyrimidines; Sucrose; Tritium | 1988 |
Effect of nutritional state and allopurinol on purine metabolism in the rat small intestine.
Topics: Adenine; Allopurinol; Animals; Eating; Fasting; Guanine; Hypoxanthine; Hypoxanthines; Inosine; Intestine, Small; Male; Nutritional Status; Purines; Rats; Rats, Inbred Strains | 1988 |
Adenine and guanine complexes with acridine orange dye: study of semiconductive properties.
Topics: Acridine Orange; Adenine; Electric Conductivity; Guanine; Semiconductors | 1987 |
Expression of a novel high-affinity purine nucleobase transport function in mutant mammalian T lymphoblasts.
Topics: Adenine; Animals; Azaserine; Biological Transport, Active; Cell Line; Dipyridamole; Guanine; Hypoxanthine; Hypoxanthines; Kinetics; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Mutation; Phenotype; Purine Nucleosides; T-Lymphocytes; Thioinosine | 1986 |
Distinct effects of adenine and guanine starvation on DNA synthesis associated with different pool sizes of nucleotide precursors.
Topics: Adenine; Animals; Cell Compartmentation; Cell Cycle; Cell Line; Deoxyadenosines; DNA Replication; DNA, Neoplasm; Guanine; Lymphoma; Mice; Nucleotides; RNA, Neoplasm; T-Lymphocytes | 1987 |
The isolation and characterization of an alkylating-agent-sensitive yeast mutant, ngs1.
Topics: Adenine; Alkylating Agents; DNA Repair; Genes, Fungal; Guanine; Methylnitronitrosoguanidine; Mutation; Saccharomyces cerevisiae; Sulfuric Acid Esters | 1986 |
Guanine and adenine analogues as tools in the investigation of the mechanisms of mismatch repair in E. coli.
Topics: Adenine; Base Sequence; Codon; Coliphages; DNA Repair; Escherichia coli; Guanine; Methylation; Mutation | 1986 |
Differential enhancement of spontaneous transition mutations in the lacI gene of an Ung- strain of Escherichia coli.
Topics: Adenine; Cytosine; Deamination; DNA Glycosylases; Escherichia coli; Guanine; Lac Operon; Mutation; N-Glycosyl Hydrolases; Thymine; Uracil-DNA Glycosidase | 1986 |
Mutagenic and promutagenic properties of DNA adducts formed by vinyl chloride metabolites.
Topics: Acetaldehyde; Adenine; Alkylating Agents; Animals; Carcinogens; Cytosine; DNA Damage; DNA Replication; Dose-Response Relationship, Drug; Escherichia coli; Ethylene Oxide; Guanine; Mutagens; Vinyl Chloride; Vinyl Compounds | 1986 |
O6-methylguanine specifically induces AT----GC transition mutations.
Topics: 5-Methylcytosine; Adenine; Alkylation; Base Composition; Cytosine; DNA Damage; DNA, Bacterial; Escherichia coli; Guanine; Hypoxanthine; Hypoxanthines; Mutation | 1987 |
Expression of the high-affinity purine nucleobase transporter in mutant mouse S49 cells does not require a functional wild-type nucleoside-nucleobase transporter.
Topics: Adenine; Animals; Carrier Proteins; Cell Division; Cell Line; Guanine; Hypoxanthine; Hypoxanthines; Kinetics; Membrane Proteins; Membrane Transport Proteins; Mice; Mutation; Nucleobase Transport Proteins; Nucleoside Transport Proteins; Nucleosides; Phenotype | 1987 |
Selective inhibitory effect of (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine and 2'-nor-cyclic GMP on adenovirus replication in vitro.
Topics: Adenine; Adenoviruses, Human; Antiviral Agents; Cells, Cultured; Cytopathogenic Effect, Viral; Fibroblasts; Guanine; Humans; Organophosphonates; Organophosphorus Compounds; Virus Replication | 1987 |
Transfer of human genes conferring resistance to methylating mutagens, but not to UV irradiation and cross-linking agents, into Chinese hamster ovary cells.
Topics: Adenine; Alkylating Agents; Animals; Cricetinae; Cross-Linking Reagents; DNA Repair; Genes; Guanine; Humans; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Transfection; Ultraviolet Rays | 1987 |
Effect of testosterone on purine synthesis de novo in rat perineal muscle in vivo.
Topics: Adenine; Animals; Carbon Radioisotopes; Formates; Guanine; Hypoxanthine; Hypoxanthines; Male; Muscle, Smooth; Muscles; Orchiectomy; Purines; Rats; Rats, Inbred Strains; Sexual Maturation; Testosterone | 1987 |
Excretion of methylated nucleic acid bases as an indicator of exposure to nitrosatable drugs.
Topics: Adenine; Animals; Female; Guanine; Methylation; Nitroso Compounds; Nucleic Acids; Rats | 1987 |
Guanine is a growth factor for Legionella species.
Topics: Adenine; Culture Media; Cytosine; Growth Substances; Guanine; Hydrogen-Ion Concentration; Hypoxanthine; Hypoxanthines; Legionella; Nucleosides; Nucleotides; Thymine; Uracil; Xanthine; Xanthines | 1986 |
Specific DNA alkylation damage and its repair in carcinogen-treated rat liver and brain.
Topics: Adenine; Alkylating Agents; Animals; Brain; Carcinogens; DNA; DNA Repair; Guanine; Hydrogen-Ion Concentration; Hydrolysis; Liver; Male; Methyl Methanesulfonate; Methylnitrosourea; Rats; Rats, Inbred Strains | 1986 |
Chemical reclosure of opened imidazole ring of guanine.
Topics: Adenine; Buffers; Chemical Phenomena; Chemistry; DNA; Guanine; Hydrochloric Acid; Hydrogen-Ion Concentration; Imidazoles; Kinetics | 1986 |
Base-pair mismatches in DNA fragments.
Topics: Adenine; Base Sequence; Crystallization; DNA; Guanine; Models, Molecular; Nucleic Acid Conformation; Thymidine; X-Ray Diffraction | 1986 |
Formation of O6-ethylthioethylguanine in DNA by reaction with the sulfur mustard, chloroethyl sulfide, and its apparent lack of repair by O6-alkylguanine-DNA alkyltransferase.
Topics: Adenine; Alkylation; Animals; Cattle; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA; DNA Repair; Guanine; Methyltransferases; Mustard Compounds; Mustard Gas; O(6)-Methylguanine-DNA Methyltransferase | 1986 |
The hormonal regulation of purine biosynthesis: control of the inosinic acid branch point.
Topics: Adenine; Animals; Guanine; Inosine Monophosphate; Inosine Nucleotides; Male; Muscles; Orchiectomy; Organ Size; Purines; Rats; Testosterone | 1986 |
An extended semi-empirical molecular orbital study of the pi pi excited states of nucleic acid bases.
Topics: Adenine; Cytosine; Guanine; Nucleic Acid Conformation; Spectrophotometry, Ultraviolet; Uracil; Vacuum | 1986 |
Reactions of nucleosides with glyoxal and acrolein.
Topics: Acrolein; Adenine; Aldehydes; Chemical Phenomena; Chemistry; Cytosine; Glyoxal; Guanine; Guanosine; Nucleosides | 1986 |
The role of cyclic nucleic acid base adducts in carcinogenesis and mutagenesis.
Topics: Adenine; Alkylating Agents; Carcinogens; Cytosine; DNA; DNA Damage; Guanine; Heterocyclic Compounds; Mutagens | 1986 |
Repair of etheno DNA adducts by N-glycosylases.
Topics: Acetaldehyde; Adenine; Adenosine; DNA Glycosylases; DNA Repair; Guanine; Guanosine; N-Glycosyl Hydrolases; Substrate Specificity | 1986 |
DNA alkylation repair and the induction of cell death and sister chromatid exchange in human cells.
Topics: Adenine; Alkylating Agents; Alkylation; Cell Survival; DNA Repair; Guanine; HeLa Cells; Humans; Methylnitronitrosoguanidine; Purines; Sister Chromatid Exchange | 1987 |
Synthesis and biological properties of 9-(trans-4-hydroxy-2-buten-1-yl)adenine and guanine: open-chain analogues of neplanocin A.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Antibiotics, Antineoplastic; Guanine; Indicators and Reagents; Leukemia L1210; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 1987 |
Antitumor agents. 86. Synthesis and cytotoxicity of alpha-methylene-gamma-lactone-bearing purines.
Topics: Adenine; Animals; Antineoplastic Agents; Cell Survival; Guanine; Humans; Hypoxanthines; Indicators and Reagents; KB Cells; Lactones; Leukemia L1210; Leukemia P388; Mice; Structure-Activity Relationship | 1987 |
Repair of chemical carcinogen-induced damage in DNA of human lymphocytes and lymphoid cell lines--studies of the kinetics of removal of O6-methylguanine and 3-methyladenine.
Topics: Adenine; Autoimmune Diseases; Carcinogens; Cell Line; DNA Repair; Guanine; Humans; Kinetics; Lymphocytes; Mathematics; Models, Chemical | 1986 |
Purification and characterization of 3-methyladenine-DNA glycosylase from calf thymus.
Topics: Adenine; Animals; Cattle; Chemical Phenomena; Chemistry, Physical; Chromatin; DNA Glycosylases; Guanine; Hot Temperature; Isoelectric Point; Kinetics; Molecular Weight; N-Glycosyl Hydrolases; Substrate Specificity; Sulfhydryl Compounds; Thymus Gland | 1985 |
Flexibility of nucleic acid bases and its possible relationship with carcinogenesis.
Topics: Adenine; Animals; Cytosine; DNA; Guanine; Humans; Hydrogen Bonding; Neoplasms; Nucleic Acid Conformation; Uracil | 1985 |
The biochemical basis of 5-bromouracil- and 2-aminopurine-induced mutagenesis.
Topics: 2-Aminopurine; Adenine; Base Composition; Bromouracil; Cytosine; Deoxycytosine Nucleotides; Deoxyribonucleotides; Deoxyuracil Nucleotides; Guanine; Mutation; Nucleic Acid Heteroduplexes; Thymine | 1985 |
Erythroid induction of K562 human leukemia cells: enhancement by purines.
Topics: Adenine; Cell Cycle; Cell Division; Cell Line; Drug Synergism; Guanine; Hemoglobins; Humans; Hypoxanthine; Hypoxanthines; Leukemia; Mycophenolic Acid; Thymidine; Xanthine; Xanthines | 1985 |
Studies on the mechanism of cytotoxicity of 3-deazaguanosine in human cancer cells.
Topics: Adenine; Cell Division; Cells, Cultured; DNA; Formates; GMP Reductase; Guanine; Guanosine; Humans; NADH, NADPH Oxidoreductases; Neoplasms; Purines | 1985 |
DNA sequence has an effect on the extent and kinds of alkylation of DNA by a potent carcinogen.
Topics: Adenine; Alkylation; Animals; Base Sequence; Cattle; DNA; Guanine; Methylnitrosourea; Polydeoxyribonucleotides; Structure-Activity Relationship; Thymus Gland; Tritium | 1985 |
Direct alkylation of calf thymus DNA by acrylonitrile. Isolation of cyanoethyl adducts of guanine and thymine and carboxyethyl adducts of adenine and cytosine.
Topics: Acrylonitrile; Adenine; Alkylation; Animals; Cattle; Cytosine; DNA; Guanine; Mass Spectrometry; Nitriles; Structure-Activity Relationship; Thymidine; Thymus Gland | 1985 |
Mechanisms of ageing.
Topics: Adenine; Aging; Cytosine; Genetic Code; Genetics, Medical; Guanine; Humans; Thymine | 1970 |
Stereochemistry of actinomycin binding to DNA. II. Detailed molecular model of actinomycin-DNA complex and its implications.
Topics: Adenine; Base Sequence; Binding Sites; Computers; Cytosine; Dactinomycin; DNA; Guanine; Guanosine; Hydrogen; Macromolecular Substances; Models, Chemical; Models, Structural; Nucleotides; Purines; Pyrimidines; Thymine | 1972 |
Release of free bases from deoxyribonucleic acid after reaction with bleomycin.
Topics: Adenine; Animals; Antibiotics, Antineoplastic; Bacillus subtilis; Bleomycin; Carbon Isotopes; Cattle; Centrifugation, Density Gradient; Chemical Phenomena; Chemistry; Chromatography, Paper; Cytosine; Deoxyribonucleases; DNA, Bacterial; Guanine; Hydrolysis; Molecular Weight; Nucleic Acid Conformation; Pancreas; Phosphoric Diester Hydrolases; Phosphorus Isotopes; Snakes; Thymine; Tritium; Ultracentrifugation; Venoms | 1972 |
DNA composition in Rickettsia mooseri by base analysis.
Topics: Adenine; Chromatography, Paper; Cytosine; DNA, Bacterial; Guanine; Hydrolysis; Rickettsia; Spectrophotometry, Ultraviolet; Thymine | 1973 |
Isolation of cyclic AMP and cyclic GMP by thin-layer chromatography. Application to assay of adenylate cyclase, guanylate cyclase, and cyclic nucleotide phosphodiesterase.
Topics: Adenine; Adenosine Triphosphate; Adenylyl Cyclases; Alloxan; Animals; Anura; Carbon Radioisotopes; Cell Membrane; Chromatography, Ion Exchange; Chromatography, Thin Layer; Cyclic AMP; Cyclic GMP; Evaluation Studies as Topic; Glucagon; Guanine; Guanosine Triphosphate; Guanylate Cyclase; Kinetics; Liver; Lung; Methods; Phosphoric Diester Hydrolases; Photoreceptor Cells; Rats; Time Factors; Tritium | 1974 |
[Some properties of messenger ribonucleic acid isolated from rabbit reticulocytes].
Topics: Adenine; Animals; Chemical Phenomena; Chemistry; Chromatography; Cytosine; Genetic Code; Guanine; In Vitro Techniques; Rabbits; Reticulocytes; Ribosomes; RNA; RNA, Messenger; Ultracentrifugation; Uracil | 1965 |
Incorporation of protein and nucleic acid precursors into frog nervous tissue in vitro.
Topics: Adenine; Animals; Antithyroid Agents; Anura; Azides; Brain; Cyanides; Dinitrophenols; DNA; Ganglia; Guanine; In Vitro Techniques; Nucleosides; RNA; Thymidine; Uridine; Valine | 1966 |
[Initial stages of ribonucleic acid synthesis in HeLa cells].
Topics: Adenine; Culture Techniques; Cytosine; DNA; Guanine; HeLa Cells; Phosphates; Phosphorus Isotopes; RNA; Tritium; Uracil; Uridine | 1966 |
The mode of action of quinoxaline antibiotics. Interaction of quinomycin A with deoxyribonucleic acid.
Topics: Adenine; Anti-Bacterial Agents; Chromatography; Dactinomycin; DNA; DNA, Bacterial; Escherichia coli; Guanine; Nucleotides; Protein Biosynthesis; Purines; RNA; RNA, Bacterial; Serum Albumin; Spectrum Analysis; Staphylococcus; Sulfates; Uracil | 1967 |
The deoxyribonucleic acids of some BCG substrains.
Topics: Adenine; Chromatography, Paper; Cytosine; DNA, Bacterial; Guanine; Mycobacterium bovis; Thymine | 1968 |
[Guanosine 5'-triphosphate (GTP) in 5'-terminal position of RNA during synthesis in HeLa cells and rat liver].
Topics: Adenine; Animals; Dialysis; Guanine; Guanine Nucleotides; HeLa Cells; Liver; Phosphorus Isotopes; Rats; RNA; Tritium | 1969 |
Stalked bacteria: properties of deoxriybonucleic acid bacteriophage phiCbK.
Topics: Adenine; Bacteria; Bacteriophages; Carbon Isotopes; Centrifugation, Density Gradient; Centrifugation, Zonal; Cesium; Chlorides; Cytosine; DNA, Viral; Guanine; Hot Temperature; Microscopy, Electron; Nucleic Acid Denaturation; Phosphorus Isotopes; Phosphotungstic Acid; Staining and Labeling; Thymine | 1970 |
Metastable secondary structures in ribosomal RNA molecular hysteresis in the acid-base titration of Escherichia coli ribosomal RNA.
Topics: Adenine; Edetic Acid; Escherichia coli; Guanine; Hydrogen-Ion Concentration; Kinetics; Magnesium; Nucleic Acid Conformation; Osmolar Concentration; Potentiometry; RNA, Bacterial; RNA, Ribosomal; RNA, Transfer; Sodium; Spectrophotometry, Ultraviolet; Time Factors | 1973 |
Characterization of virus-specific RNAs from subacute sclerosing panencephalitis virus-infected CV-1 cells.
Topics: Adenine; Animals; Carbon Radioisotopes; Cell Line; Cells, Cultured; Centrifugation, Density Gradient; Cesium; Cytosine; Electrophoresis, Polyacrylamide Gel; Encephalitis Viruses; Guanine; Haplorhini; Kidney; Measles virus; Nucleic Acid Hybridization; Phosphorus Radioisotopes; RNA, Ribosomal; RNA, Viral; Subacute Sclerosing Panencephalitis; Sucrose; Time Factors; Tritium; Uridine | 1973 |
tRNA methylases from HeLa cells: purification and properties of an adenine-1-methylase and a guanine-N2-methylase.
Topics: Adenine; Bacillus subtilis; Carbon Radioisotopes; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Escherichia coli; Guanine; HeLa Cells; Humans; Kinetics; RNA, Bacterial; RNA, Transfer; Species Specificity; Spectrophotometry, Ultraviolet; Time Factors; tRNA Methyltransferases | 1974 |
[Action of highly polymerized nucleic acids and their bases on the survival of thymocytes of rats irradiated in vitro].
Topics: Adenine; Animals; Cytosine; DNA; Guanine; In Vitro Techniques; Purines; Pyrimidines; Radiation Effects; Rats; RNA; Thymine; Thymus Gland; Uracil | 1966 |
Use of nuclear magnetic resonance in determining molecular structure of urinary constituents of low molecular weight.
Topics: Adenine; Aniline Compounds; Creatinine; Guanine; Hypoxanthines; Magnetic Resonance Spectroscopy; Niacinamide; Phenacetin; Uracil; Uridine; Urine | 1968 |
Protein and nucleic acid synthesis in rat mammary glands during early lactation.
Topics: Adenine; Aldehyde-Lyases; Animals; Aspartate Aminotransferases; Caseins; Cytosine; DNA; Female; Glucosephosphate Dehydrogenase; Guanine; Hydrocortisone; Hypophysectomy; Lactation; Leucine; Malate Dehydrogenase; Mammary Glands, Animal; Phosphofructokinase-1; Phosphoglucomutase; Phosphogluconate Dehydrogenase; Pregnancy; Prolactin; Protein Biosynthesis; Rats; RNA; Uridine | 1968 |
Inactivation of the phages of Staphylococcus aureus by hydroxylamine.
Topics: Adenine; Bacteriological Techniques; Cytosine; Depression, Chemical; DNA, Viral; Guanine; Hydroxylamines; Serotyping; Species Specificity; Staphylococcus Phages; Thymine | 1968 |
[Reciprocal modifications of nervous excitability under the effect of purine and pyrimidine bases].
Topics: Adenine; Animals; Cytosine; Guanine; Nervous System; Purines; Pyrimidines; Rats; Thymine; Uracil | 1968 |
Biochemical correlates of cardiac hypertrophy. II. Increased rate of RNA synthesis in experimental cardiac hypertrophy in the rat.
Topics: Adenine; Adenine Nucleotides; Animals; Cardiomegaly; Centrifugation, Density Gradient; Cytosine; Female; Guanine; Myocardium; Organ Size; Phosphorus Isotopes; Rats; RNA; Tritium; Uracil Nucleotides; Uridine | 1969 |
Base composition of DNA in adenovirus-12-induced tumor.
Topics: Abdominal Neoplasms; Adenine; Adenoviridae; Animals; Brain; Chromatography, Paper; Cricetinae; Cytosine; DNA; DNA, Neoplasm; Guanine; Humans; Infant, Newborn; Liver; Microscopy, Electron; Neoplasms, Experimental; Nucleic Acid Denaturation; Temperature; Thymine | 1969 |
The influence of ribonucleic acid & some of its structural constituents on metal toxicities in Corcyra cephalonica St.
Topics: Adenine; Animals; Cobalt; Guanine; Insecta; Larva; Nickel; RNA; Zinc | 1970 |
Chemically defined media for Pasteurella multocida and Pasteurella ureae, and a comparison of their thiamine requirements with those of Pasteurella haemolytica.
Topics: Adenine; Amino Acids; Bacteriological Techniques; Chromatography, Paper; Citrates; Culture Media; Densitometry; Glucose; Guanine; Niacinamide; Pantothenic Acid; Pasteurella; Species Specificity; Sucrose; Thiamine; Uracil | 1970 |
[Influence of S-adenosylmethionine on the methylation of the RNA by dimethylnitrosamine in vivo].
Topics: Adenine; Animals; Body Weight; Carbon Isotopes; Chromatography, Ion Exchange; Female; Guanine; Hydrochloric Acid; Hydrolysis; Injections, Intravenous; Liver; Male; Methionine; Methylation; Mice; Nitrosamines; Nucleosides; Rats; RNA; S-Adenosylmethionine; Spectrophotometry; Tritium | 1970 |
RNA ssynthesis by Down's syndrome Leucocytes.
Topics: Adenine; Centrifugation, Density Gradient; Child; Cytosine; Down Syndrome; Female; Guanine; Humans; Leukocytes; Male; RNA; Time Factors; Tritium; Uracil; Uridine | 1971 |
Requirements for growth of Pasteurella ureae in a chemically defined medium.
Topics: Adenine; Amino Acids; Carbohydrate Metabolism; Culture Media; Guanine; Hypoxanthines; Niacinamide; Pantothenic Acid; Pasteurella; Uracil; Xanthines | 1972 |
Activities of hypoxanthine-guanine phosphoribosyltransferase and adenine phosphoribosyltransferase in erythrocytes from patients with Down's syndrome.
Topics: Adenine; Child; Chromosomes, Human, 21-22 and Y; Down Syndrome; Erythrocytes; Guanine; Humans; Hypoxanthines; Pentosyltransferases; Uric Acid | 1972 |
Molecular and cellular mechanisms associated with pulse-carcinogenesis in the rat nerbous system by ethyinitrosourea: ethylation of nucleic acids and elimination rates of ethylated bases from the DNA of different tissues.
Topics: Adenine; Alkylation; Animals; Autoradiography; Brain Chemistry; Brain Neoplasms; Carbon Radioisotopes; Cell Transformation, Neoplastic; Chemical Phenomena; Chemistry; Chromatography; DNA; DNA Replication; Female; Fetus; Guanine; In Vitro Techniques; Liver; Male; Maternal-Fetal Exchange; Neoplasms, Experimental; Nervous System; Nitrosamines; Nitrosourea Compounds; Nucleic Acids; Pregnancy; Rats; Rats, Inbred Strains; Tritium | 1974 |
Radiation sensitivity of cells and base composition of DNA: an electron spin resonance study.
Topics: Adenine; Animals; Bacteria; Cytosine; DNA; DNA, Bacterial; Electron Spin Resonance Spectroscopy; Guanine; In Vitro Techniques; Radiation Effects; Ribose; RNA; Thymine; Thymus Gland; Uracil; Yeasts | 1966 |
Characterization of ribonuclease-resistant RNA from poliovirus-infected HeLa cells.
Topics: Adenine; Centrifugation; Cytosine; Guanine; HeLa Cells; Hot Temperature; Humans; In Vitro Techniques; Neoplasms, Experimental; Poliovirus; Ribonucleases; RNA, Viral; Spectrophotometry; Uracil | 1965 |
Effect of purines on epinephrine-induced lipolysis in adipose tissue.
Topics: Adenine; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Caffeine; Enzymes; Epinephrine; Fatty Acids; Guanine; Hypoxanthines; In Vitro Techniques; Lipid Metabolism; Purines; Rats; Uric Acid; Xanthines | 1966 |
Radical yields in some nucleic acid constituents.
Topics: Adenine; Cytosine; Electron Spin Resonance Spectroscopy; Guanine; Nucleic Acids; Thymine; Uracil | 1966 |
Electron spin resonance examination of charge transfer complexes of polycyclic carcinogens and nucleic acid bases.
Topics: Acridines; Adenine; Benz(a)Anthracenes; Benzopyrenes; Chemical Phenomena; Chemistry; Cytosine; Diethylstilbestrol; Electron Spin Resonance Spectroscopy; Estradiol; Estrone; Fluorenes; Guanine; Iodine; Methylcholanthrene; Uracil | 1966 |
Biochemical effects of formycin, an adenosine analog.
Topics: Adenine; Animals; Anti-Bacterial Agents; Antineoplastic Agents; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Diphosphates; Glucose; Glucosyltransferases; Glutamine; Glycine; Guanine; Hypoxanthines; Lysine; Methionine; Nucleosides; Nucleotides; Phosphates; Phosphotransferases; Proteins; Purines | 1967 |
Purine N-oxides. XIX. On the oncogenic N-oxide derivatives of guanine and xanthine and a nononcogenic isomer of xanthine N-oxide.
Topics: Adenine; Animals; Carcinoma, Hepatocellular; Guanine; Liver Neoplasms; Mercaptopurine; Neoplasms; Neoplasms, Experimental; Oxides; Rats; Xanthines | 1967 |
Studies of nucleotide sequences in tobacco mosaic virus ribonucleic acid. IV. Use of aniline in stepwise degradation.
Topics: Adenine; Alkaline Phosphatase; Aniline Compounds; Chemical Phenomena; Chemistry; Cytosine; Guanine; Periodic Acid; RNA, Viral; Tobacco Mosaic Virus; Uracil | 1966 |
Base sequence at the 5'-linked terminus of tobacco mosaic virus ribonucleic acid.
Topics: Adenine; Carbon Isotopes; Chemical Phenomena; Chemistry, Physical; Chromatography, Ion Exchange; Cytosine; Guanine; Phosphoric Monoester Hydrolases; Ribonucleases; RNA, Viral; Semicarbazides; Spleen; Tobacco Mosaic Virus | 1967 |
[Purine synthesis in the mouse hepatoma and liver tissue].
Topics: Adenine; Adenine Nucleotides; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Formates; Guanine; Liver; Liver Neoplasms; Mice; Nucleic Acids; Serine | 1966 |
Studies on a 32S component of nuclear RNA.
Topics: Adenine; Animals; Carcinoma, Hepatocellular; Cell Nucleus; Centrifugation, Zonal; Chromatography, Gel; Cytosine; Guanine; Liver; Liver Neoplasms; Neoplasms, Experimental; Phosphorus Isotopes; Rats; Ribosomes; RNA; RNA, Neoplasm; Uridine | 1967 |
[Separation of nucleic acids by thin layer chromatography].
Topics: 1-Propanol; Adenine; Cellulose; Chromatography, Thin Layer; Cytosine; Guanine; Nucleic Acids; Perchlorates; Thymine; Uracil | 1966 |
Analysis of the 5'-terminal nucleotide sequences of ribonucleic acids. II. Comparison of the 5'-terminal nucleotide sequences of ribosomal RNA's from different organisms.
Topics: Adenine; Adenosine Triphosphate; Bacillus cereus; Bacillus subtilis; Centrifugation, Density Gradient; Chromatography, Gel; Cytosine; Guanine; Nucleotides; Pancreas; Phosphoric Monoester Hydrolases; Phosphotransferases; Polynucleotides; Ribonucleases; Ribosomes; RNA; RNA, Bacterial; Saccharomyces; Sarcina; Thymine | 1967 |
[Study of radical stages of low-temperature radiolysis of some heteroaromatic compounds-components of nucleic acids].
Topics: Adenine; Cytosine; DNA; Electron Spin Resonance Spectroscopy; Free Radicals; Guanine; Radiochemistry; Temperature; Thymine; Uracil | 1966 |
Analysis of nearest neighbour base frequencies in the RNA of a mammalian virus: encephalomyocarditis virus.
Topics: Adenine; Animals; Cytosine; DNA; DNA, Viral; Encephalomyocarditis virus; Guanine; Mice; Polyomavirus; RNA, Viral; Uracil | 1968 |
Kinetic and spectrophotometric studies on the renaturation of deoxyribonucleic acid.
Topics: Adenine; Animals; Bordetella pertussis; Chemical Phenomena; Chemistry; Coliphages; Cytosine; DNA, Bacterial; DNA, Viral; Escherichia coli; Guanine; Kinetics; Spectrophotometry; Spectrum Analysis; Temperature; Thymine; Time Factors | 1968 |
Effect of gamma-radiation on aqueous solutions of DNA's of different base composition.
Topics: Adenine; Animals; Bacteria; Cattle; Clostridium perfringens; Cytosine; DNA; Enterobacter; Escherichia coli; Guanine; Hot Temperature; Mathematics; Micrococcus; Nucleic Acid Denaturation; Pseudomonas; Radiation Effects; Species Specificity; Spectrum Analysis; Staphylococcus; Thymine; Thymus Gland; Ultraviolet Rays | 1968 |
Determination of melting sequences in DNA and DNA-protein complexes by difference spectra.
Topics: Adenine; Animals; Cattle; Chromatography, Ion Exchange; Clostridium perfringens; Cytosine; DNA; DNA, Bacterial; Escherichia coli; Guanine; Hot Temperature; Light; Methods; Mice; Nucleic Acid Denaturation; Nucleoproteins; Spectrophotometry; Thymine | 1969 |
A convenient spectrophotometric assay for phosphodiesterases, using dinucleoside-monophosphates as substrates.
Topics: Adenine; Aminohydrolases; Animals; Guanine; Kinetics; Methods; Models, Biological; Nucleotides; Phosphoric Monoester Hydrolases; Ribonucleases; Snakes; Spectrophotometry; Spleen; Venoms | 1969 |
Analysis of nucleic acid derivatives at the subnanomole level. 3. A tritium labeling procedure for quantitative analysis of ribose derivatives.
Topics: Adenine; Boron Compounds; Chromatography, Thin Layer; Cytosine; Guanine; Methods; Microchemistry; Nucleosides; Oxidation-Reduction; Periodic Acid; Polynucleotides; Ribose; Spectrophotometry; Tritium; Uracil | 1969 |
Analysis of poliovirus-specific RNA in infected HeLa cells by polyacrylamide gel electrophoresis.
Topics: Adenine; Centrifugation, Density Gradient; Centrifugation, Zonal; Chemistry Techniques, Analytical; Cytosine; Electrophoresis, Disc; Guanine; HeLa Cells; Methods; Phenols; Poliovirus; Ribonucleases; RNA, Viral; Surface-Active Agents; Uracil | 1969 |
[Perfusion of the isolated liver. Changes in the time of tissue electronic paramagnetic resonance (or ESR, electrospin resonance)].
Topics: Adenine; Animals; Electron Spin Resonance Spectroscopy; Guanine; Histocytochemistry; Liver; Perfusion; Purines; Pyrimidines; Rats | 1969 |
Metallocinium cations, nucleic acids and proteins.
Topics: Adenine; Chemical Phenomena; Chemistry, Physical; Chromium; Cobalt; Cobalt Isotopes; Electron Spin Resonance Spectroscopy; Electrons; Guanine; Hydrogen; Iron; Magnetic Resonance Spectroscopy; Nucleic Acids; Organometallic Compounds; Oxidation-Reduction; Proteins; RNA; Spectrum Analysis; Tryptophan; Tyrosine | 1969 |
Ribonucleic acid content of encephalomyocarditis virus.
Topics: Adenine; Chromatography; Cytosine; Encephalomyocarditis virus; Guanine; Nitrogen; Phosphorus; Proteins; RNA, Viral; Spectrophotometry; Ultraviolet Rays; Uracil | 1970 |
Specific acylation of the guanine residues of ribonucleic acid.
Topics: Adenine; Aldehydes; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Cytosine; Guanine; Magnetic Resonance Spectroscopy; Nitrites; Periodic Acid; Phosphoric Monoester Hydrolases; Propionates; RNA; Yeasts | 1970 |
Possibility of anion formation in irradiated frozen solutions of nucleic acid bases.
Topics: Adenine; Cytosine; DNA; Electron Spin Resonance Spectroscopy; Free Radicals; Freezing; Guanine; Hydrogen-Ion Concentration; Kinetics; Light; Nucleic Acids; Purines; Pyrimidines; Radiation Effects; Sodium Hydroxide; Solutions; Temperature; Thymine | 1970 |
Characterization of the Kilham rat virus.
Topics: Adenine; Animals; Carbon Isotopes; Cell Line; Centrifugation, Density Gradient; Cesium; Chlorides; Cytosine; Densitometry; DNA Viruses; DNA, Viral; Formaldehyde; Guanine; Hemagglutination Inhibition Tests; Hemagglutination Tests; Hot Temperature; Microscopy, Electron; Molecular Weight; Nucleic Acid Denaturation; Rats; Spectrophotometry; Sucrose; Thymidine; Thymine; Tritium; Viruses, Unclassified; Wilms Tumor | 1970 |
Base sequence and evolution of guinea-pig alpha-satellite DNA.
Topics: Adenine; Animals; Biological Evolution; Cytosine; DNA; Electrophoresis; Guanine; Guinea Pigs; Molecular Biology; Mutation; Nucleotides; Phosphoric Monoester Hydrolases; Thymine | 1970 |
A new rapid electrophoretic method for determination of deoxyribonucleic acid base composition.
Topics: Adenine; Agar; DNA; Electrophoresis; Guanine; Hydrogen-Ion Concentration; Methods; Nucleosides; Nucleotides; Perchlorates; Pressure; Spectrophotometry; Thymine; Time Factors | 1969 |
Effects of orotic acid on purine and lipoprotein metabolism in man.
Topics: Adenine; Administration, Oral; Carbon Isotopes; Cholesterol; Diphosphates; Erythrocytes; Glycine; Guanine; Humans; Kidney; Lipoproteins; Metabolic Clearance Rate; Nitrogen; Orotic Acid; Purines; Radioisotopes; Ribose; Transferases; Triglycerides; Uric Acid | 1970 |
Molecular orbital calculations on the conformation of nucleic acids and their constituents. I. Conformational energies of beta-nucleosides with C(3')-and C(2')-endo sugars.
Topics: Adenine; Adenine Nucleotides; Bromine; Chemical Phenomena; Chemistry; Coenzymes; Cyclic AMP; Floxuridine; Glycosides; Guanine; Guanine Nucleotides; Isomerism; Mathematics; Nucleosides; Nucleotides; Pentoses; Purines; Pyrimidines; Ribose; Rotation; Thermodynamics; Thymine Nucleotides; Uracil Nucleotides; Uridine; Vitamin B 12; X-Ray Diffraction | 1971 |
Criticism of the use of methylated albumin-kieselguhr chromatography for the isolation of metabolically labile DNA.
Topics: Adenine; Centrifugation, Density Gradient; Cesium; Chemical Precipitation; Chlorides; Chromatography; Cytosine; DNA; Drug Stability; Guanine; Hot Temperature; Hydrolysis; Methylation; Nucleic Acid Denaturation; Perchlorates; Plants; Ribonucleases; RNA; Serum Albumin; Silicon Dioxide; Uracil | 1971 |
Effects of 5'-AMP and its related compounds on the ATP-induced contraction of isolated guinea-pig ileum.
Topics: Acetylcholine; Adenine; Adenine Nucleotides; Adenosine Triphosphate; Animals; Bradykinin; Cyclic AMP; Cytosine; Drug Synergism; Glycerol; Guanine; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Nucleosides; Potassium; Rabbits; Uracil; Xanthines | 1971 |
Methylation of deoxyribonucleic acid during hormonal stimulation of mammary cells in vitro.
Topics: Adenine; Alkaline Phosphatase; Animals; Bromodeoxyuridine; Carbon Isotopes; Cell Differentiation; Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; Chromatography, Paper; Cytosine; DNA; DNA Replication; Epithelial Cells; Female; Formates; Guanine; Hydrocortisone; Insulin; Kinetics; Mammary Glands, Animal; Methionine; Methylation; Mice; Organ Culture Techniques; Pancreas; Peptide Hydrolases; Phosphoric Monoester Hydrolases; Pregnancy; Prolactin; Ribonucleases; Sheep; Sodium; Thymidine; Thymine; Tritium; Venoms | 1971 |
The regulation of purine utilization in bacteria. III. The involvement of purine phosphoribosyltransferases in the uptake of adenine and other nucleic acid precursors by intact resting cells.
Topics: Acetamides; Adenine; Adenine Nucleotides; Adenosine Monophosphate; Bacteriolysis; Biological Transport; Carbon Isotopes; Culture Media; Cytosine; Escherichia coli; Fructosephosphates; Glucose; Guanine; Guanine Nucleotides; Hypoxanthines; Inosine Nucleotides; Iodoacetates; Kinetics; Nucleotides; Pentosephosphates; Pentosyltransferases; Phosphoric Acids; Purines; Ribose; Uracil | 1971 |
Studies in prebiotic synthesis. IV. Conversion of 4-aminoimidazole-5-carbonitrile derivatives to purines.
Topics: Adenine; Amides; Amidines; Amines; Carbonates; Chemical Phenomena; Chemistry; Chromatography, Paper; Cyanates; Guanine; Hydrogen Cyanide; Hydrogen-Ion Concentration; Hydrolysis; Imidazoles; Nitriles; Photochemistry; Purines; Quaternary Ammonium Compounds; Temperature; Time Factors; Urea | 1968 |
Specific RNA methylase associated with avian myeloblastosis virus.
Topics: Adenine; Autoradiography; Avian Leukosis Virus; Centrifugation; Chromatography; Chromatography, Ion Exchange; Cytosine Nucleotides; Freezing; Guanine; Hot Temperature; Hydrolysis; Methylation; Methyltransferases; Microscopy, Electron; RNA; RNA, Transfer; Tritium; Uracil Nucleotides | 1971 |
Chemical structural requirements for induction of oocyte maturation and spawning in starfishes.
Topics: Adenine; Adenosine Triphosphate; Animals; Cyclic AMP; Cytidine; Cytosine; Female; Guanine; Guanine Nucleotides; Guanosine; Hypoxanthines; Inosine; Inosine Nucleotides; Ovum; Starfish; Stimulation, Chemical; Xanthines | 1971 |
Mechanisms of radical formation in irradiated purine bases and derivatives: an E.P.R. study using computer technique.
Topics: Adenine; Adenosine Monophosphate; Computers; Deoxyribonucleosides; Electron Spin Resonance Spectroscopy; Free Radicals; Guanine; Guanine Nucleotides; Radiochemistry; Ribonucleotides | 1972 |
The uptake and incorporation of purines by wild-type Saccharomyces cerevisiae and a mutant resistant to 4-aminopyrazolo (3,4-d) pyrimidine.
Topics: Adenine; Amines; Aza Compounds; Carbon Isotopes; Diphosphates; Drug Resistance, Microbial; Genetics, Microbial; Guanine; Hypoxanthines; Kinetics; Membrane Transport Proteins; Mutation; Pentosephosphates; Pentosyltransferases; Purines; Pyrazoles; Pyrimidines; Ribose; Saccharomyces; Saccharomyces cerevisiae | 1972 |
Enzymatic DNA modifications in isolated nuclei from developing sea urchin embryos.
Topics: Adenine; Aminohydrolases; Animals; Carbon Isotopes; Cell Fractionation; Cell Nucleus; Chromatography, Paper; Cytosine; Cytosine Nucleotides; DNA; Electron Transport Complex IV; Formates; Guanine; Hot Temperature; Methionine; Methylation; Methyltransferases; Proteins; S-Adenosylmethionine; Sea Urchins; Thymidine; Thymine; Tritium | 1972 |
Studies in prebiotic synthesis. VI. Synthesis of purine nucleosides.
Topics: Adenine; Adenosine; Chemical Phenomena; Chemistry; Chromatography, Paper; Diphosphates; Electrophoresis, Paper; Guanine; Guanosine; Hot Temperature; Hypoxanthines; Inosine; Kinetics; Magnesium; Nucleosides; Phosphates; Ribonucleosides; Ribose | 1972 |
Polymorphonuclear leukocyte motility in vitro. VI. Effect of purine and pyrimidine analogues: possible role of cyclic AMP.
Topics: Adenine; Caffeine; Cyclic AMP; Epinephrine; Guanine; Guanosine; Humans; Hypoxanthines; Imidazoles; Leukocytes; Movement; Purines; Pyrimidines; Reserpine; Structure-Activity Relationship; Theophylline; Thymine; Uracil; Uric Acid; Xanthines | 1972 |
Liver nucleotide metabolism in relation to amino acid supply.
Topics: Adenine; Adenine Nucleotides; Amino Acids; Animals; Carbon Isotopes; Circadian Rhythm; Dietary Proteins; Fasting; Glutamine; Glycine; Guanine; Guanine Nucleotides; Liver; Male; Nucleotides; Organ Size; Pentosephosphates; Pentosyltransferases; Phosphoric Acids; Polyribosomes; Purine Nucleotides; Rats; RNA | 1972 |
Lesch-Nyhan mutation: the influence of population density on purine phosphoribosyltransferase activities and exogenous purine utilization in monolayer cultures of skin fibroblasts.
Topics: Adenine; Carbon Isotopes; Cells, Cultured; Female; Fibroblasts; Genotype; Guanine; Heterozygote; Homozygote; Humans; Hypoxanthines; Inosine Nucleotides; Lesch-Nyhan Syndrome; Male; Mutation; Pentosephosphates; Pentosyltransferases; Phosphoric Acids; Purines; Skin; Tritium | 1972 |
MOdified nucleosides of nuclear and nucleolar low molecular weight ribonucleic acid.
Topics: Adenine; Animals; Carcinoma, Hepatocellular; Cell Nucleolus; Cell Nucleus; Chromatography, Gel; Chromatography, Thin Layer; Cytosine; Electrophoresis, Polyacrylamide Gel; Glycols; Guanine; Hypoxanthines; Liver Neoplasms; Male; Molecular Weight; Neoplasms, Experimental; Nucleosides; Rats; RNA, Neoplasm; Thymine; Uracil | 1972 |
The prostatic cell DNA-steroid association: a hypothesis of nuclear events and cytoplasmic consequences.
Topics: Adenine; Amino Acids; Base Sequence; Cytosine; DNA; DNA-Directed RNA Polymerases; DNA, Single-Stranded; Estradiol; Feedback; Fructosephosphates; Genetic Code; Guanine; Humans; Male; Models, Chemical; Peptide Initiation Factors; Peptide Termination Factors; Phosphoric Monoester Hydrolases; Prostate; Protein Biosynthesis; RNA, Messenger; RNA, Transfer; Sulfatases; Testosterone; Thymine; Transcription, Genetic | 1972 |
[Isolation and characterization of a new T4-induced nuclease].
Topics: Adenine; Chemical Phenomena; Chemistry; Coliphages; Cytosine; DNA, Viral; Guanine; Magnesium; Nucleic Acids; Phosphates; Phosphoric Monoester Hydrolases; Thymine | 1972 |
The molecular basis of mutagenesis by methyl and ethyl methanesulfonates.
Topics: Adenine; Alkanesulfonates; Alkylation; Amines; Bacillus subtilis; Bromodeoxyuridine; Chemical Phenomena; Chemistry; DNA, Bacterial; Guanine; Kinetics; Mutagens; Mutation; Nitrosoguanidines; Purines; Transformation, Genetic | 1973 |
Separation of methylated bases of ribonucleic acid by two-dimensional thin-layer chromatography.
Topics: Adenine; Adsorption; Cellulose; Chromatography, Thin Layer; Gels; Guanine; Hydrogen-Ion Concentration; Hypoxanthines; Methylation; Purines; Pyrimidines; RNA, Transfer; Silicon Dioxide; Solvents; Thymidine | 1973 |
Molecular complexity of Paramecium symbiont lambda deoxyribonucleic acid: evidence for the presence of a multicopy genome.
Topics: Adenine; Animals; Centrifugation, Density Gradient; Cytosine; DNA; Formaldehyde; Guanine; Hot Temperature; Inclusion Bodies; Kinetics; Microscopy, Electron; Microscopy, Phase-Contrast; Molecular Weight; Nucleic Acid Denaturation; Nucleic Acid Renaturation; Paramecium; Rickettsiaceae; Spectrophotometry; Thymine | 1973 |
Bases methylated in vitro by cell-free extracts of adenovirus-18-induced tumours.
Topics: Adenine; Adenoviridae Infections; Animals; Cell-Free System; Chromatography, Paper; Cricetinae; Escherichia coli; Guanine; Methylation; Methyltransferases; Neoplasms, Experimental; RNA, Bacterial; RNA, Transfer; Tumor Virus Infections | 1972 |
Differences in the patterns of methylation in rat liver ribosomal ribonucleic acid after reaction in vivo with methyl methanesulphonate and NN-dimethylnitrosamine.
Topics: Adenine; Alkanes; Alkylating Agents; Animals; Carbon Isotopes; Chromatography, Ion Exchange; Cytosine; Electrophoresis, Polyacrylamide Gel; Guanine; Hydrolysis; Liver; Methylation; Nitrosamines; Phosphoric Diester Hydrolases; Rats; Ribonucleases; RNA, Ribosomal; Sulfonic Acids | 1972 |
A new electrophoretic-autoradiographic method for the visual detection of phosphotransferases.
Topics: Adenine; Animals; Autoradiography; Carbon Isotopes; Cell Line; Chemical Precipitation; Cricetinae; Diphosphates; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Glycerol; Guanine; Hexokinase; Humans; Hybrid Cells; Hypoxanthines; Lanthanum; Liver; Lung; Methods; Mice; Pentosephosphates; Pentosyltransferases; Phosphotransferases; Ribose | 1973 |
E.P.R. of free radicals formed in DNA and its constituents after exposure to discharge-excited inert gases. II. Purines and DNA.
Topics: Adenine; Argon; Deoxyadenosines; DNA; Electron Spin Resonance Spectroscopy; Free Radicals; Guanine; Helium; Nitrogen; Radiation Effects | 1973 |
The pattern of methylated purines formed in DNA of intact and regenerating liver of rats treated with the carcinogen dimethylnitrosamine.
Topics: Adenine; Alkanesulfonates; Animals; Carbon Isotopes; Carcinogens; Chromatography, Gel; Chromatography, Ion Exchange; Dimethylamines; DNA; DNA Replication; Female; Guanine; Half-Life; Hepatectomy; Kidney; Liver; Liver Regeneration; Methylation; Nitrosamines; Rats; RNA; Spectrophotometry, Ultraviolet; Time Factors; Transcription, Genetic | 1973 |
A sensitive method for estimating 5-phosphoribosyl 1-pyrophosphate in Escherichia coli.
Topics: Adenine; Ammonium Sulfate; Carbon Isotopes; Chemical Precipitation; Chromatography, Gel; Chromatography, Thin Layer; Diphosphates; Escherichia coli; Guanine; Hot Temperature; Kinetics; Methods; Pentosephosphates; Pentosyltransferases; Ribose | 1973 |
Folate deficiency in rats bearing the Walker tumor 256 and the Novikoff hepatoma.
Topics: Adenine; Animals; Carcinoma 256, Walker; Carcinoma, Hepatocellular; Choline; Diet; FIGLU Test; Folic Acid; Folic Acid Deficiency; Formates; Glycine; Guanine; Liver Neoplasms; Male; Methionine; Neoplasms, Experimental; Rats; Serine; Thymidine; Vitamin B 12 | 1973 |
Confirmation of UAG as a nonsense codon in bakers' yeast by amino acid replacements of glutamic acid 71 in iso-1-cytochrome c.
Topics: Adenine; Amino Acid Sequence; Amino Acids; Chromatography; Cytochrome c Group; Electrophoresis; Genetic Code; Glutamates; Guanine; Leucine; Lysine; Peptide Chain Termination, Translational; Saccharomyces cerevisiae; Serine; Tryptophan; Tyrosine; Uracil | 1973 |
Conformational studies on guanosine nucleotides and polynucleotides. The effect of the base on the glycosyl and backbone conformations.
Topics: Adenine; Chemical Phenomena; Chemistry; Cyclic GMP; Energy Transfer; Guanine; Guanine Nucleotides; Hydrogen-Ion Concentration; Molecular Conformation; Optical Rotatory Dispersion; Polynucleotides; Ribonucleotides; Surface Properties; Temperature | 1973 |
Mutagenic specificity: reversion of iso-1-cytochrome c mutants of yeast.
Topics: Adenine; Alkanesulfonates; Amino Acid Sequence; Base Sequence; Cytochrome c Group; Cytosine; Genetic Code; Guanine; Imidazoles; Lactones; Mechlorethamine; Mesylates; Mutation; Nitrites; Nitrosoguanidines; Radiation Effects; Saccharomyces cerevisiae; Sulfuric Acids; Thymine; Ultraviolet Rays; Uridine | 1973 |
A comparative study of purine metabolism by human and pig erythrocytes in vitro.
Topics: Adenine; Adult; Allopurinol; Animals; Blood Glucose; Carbon Radioisotopes; Diphosphates; Erythrocytes; Guanine; Hemolysis; Humans; Hypoxanthines; Inosine; Purines; Ribose; Species Specificity; Swine; Time Factors | 1973 |
Inhibition of purine ribonucleotide and phosphoribosyl pyrophosphate synthesis by 6-cyclopentylthio-9-hydroxymethylpurine and structurally related compounds.
Topics: Adenine; Animals; Carbon Radioisotopes; Carcinoma, Ehrlich Tumor; Cell Line; Cells, Cultured; Cyclopentanes; Guanine; Hypoxanthines; Leukemia; Organophosphorus Compounds; Pentosephosphates; Phosphoric Acids; Purine Nucleotides; Purines; Ribonucleotides | 1974 |
Differences in in vivo methylation patterns of tyrosine and histidine transfer ribonucleic acids from rat liver and Novikoff hepatoma.
Topics: Adenine; Amino Acyl-tRNA Synthetases; Animals; Carcinoma, Hepatocellular; Chromatography, DEAE-Cellulose; Cytosine; Guanine; Histidine; Hypoxanthines; Liver; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Rats; Ribonucleotides; RNA, Neoplasm; RNA, Transfer; Tritium; Tyrosine | 1974 |
The effects of bases and nucleosides on the intracellular contents of nucleotides and 5-phosphoribosyl 1-pyrophosphate in Escherichia coli.
Topics: Adenine; Adenine Nucleotides; Adenosine; Carbon Radioisotopes; Cytosine Nucleotides; Escherichia coli; Guanine; Guanine Nucleotides; Guanosine; Hypoxanthines; Inosine; Inosine Nucleotides; Kinetics; Organophosphorus Compounds; Orotic Acid; Pentosephosphates; Phosphoric Acids; Ribonucleosides; Ribonucleotides; Time Factors; Uracil; Uracil Nucleotides; Uridine | 1974 |
Adenosine-mediated elevation of cyclic 3':5'-adenosine monophosphate concentrations in cultured mouse neuroblastoma cells.
Topics: Acetylcholine; Adenine; Adenosine; Animals; Benzyl Compounds; Clone Cells; Cyclic AMP; Ethers; Guanine; Guanosine; Histamine; Imidazoles; Isoproterenol; Mice; Neuroblastoma; Phosphodiesterase Inhibitors; Stimulation, Chemical; Theophylline | 1973 |
Structure and formation of free radicals in irradiated single crystals of nucleic acid constituents.
Topics: Adenine; Barbiturates; Bromodeoxyuridine; Crystallization; Electron Spin Resonance Spectroscopy; Free Radicals; Guanine; Idoxuridine; Molecular Conformation; Orotic Acid; Purines; Pyrimidines; Radiation Effects; Structure-Activity Relationship; Thymine; Uracil | 1973 |
ESR studies of radiation damage in nucleic acids, bases, nucleosides and nucleotides.
Topics: Adenine; Adenosine Monophosphate; Crystallization; Cytosine; Cytosine Nucleotides; Deoxyribonucleosides; Deoxyribose; Electron Spin Resonance Spectroscopy; Free Radicals; Freezing; Guanine; Molecular Conformation; Nucleic Acid Conformation; Purines; Pyrimidines; Radiation Effects; Ribonucleosides; Structure-Activity Relationship; Temperature; Thymine | 1973 |
Patterns of excretion of methylated purines in hepatocellular carcinoma.
Topics: Adenine; Adult; Carcinoma, Hepatocellular; Chromatography, Paper; Creatine; Guanine; Humans; Hydrolysis; Liver Cirrhosis; Liver Neoplasms; Male; Methylation; Purines | 1974 |
[Constant ratio of purine and pyrimidine bases in desoxyribonucleic acid of bull spermatozoa before and after deep-freezing].
Topics: Adenine; Animals; Cattle; Chromatography, Ion Exchange; Cytosine; DNA; Freezing; Guanine; Hydrolysis; Male; Perchlorates; Purines; Pyrimidines; Spermatozoa; Thymine | 1973 |
Polyoma DNA: a physical map.
Topics: Adenine; Autoradiography; Catalysis; Chemical Phenomena; Chemistry; Chromosome Mapping; Cytosine; DNA Replication; DNA, Viral; Electrophoresis; Escherichia coli; Gels; Genotype; Guanine; Haemophilus; Haemophilus influenzae; Microscopy, Electron; Phosphorus Radioisotopes; Polyomavirus; Thymine | 1974 |
Uptake and accumulation of purine bases by stationary yeast cells pretreated with glucose.
Topics: Adenine; Biological Transport; Calorimetry; Carbon Radioisotopes; Cell Division; Chromatography, Thin Layer; Cycloheximide; Cytosine; Glucose; Guanine; Hypoxanthines; Inosine Nucleotides; Kinetics; Models, Biological; Pentosephosphates; Pentosyltransferases; Phosphoric Acids; Phosphotransferases; Saccharomyces cerevisiae; Temperature; Thermodynamics; Time Factors | 1974 |
Effect of pharmacological agents on human keratinocyte mitosis in vitro. I. Inhibition by adenine nucleotides.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Bucladesine; Cells, Cultured; Cyclic AMP; Cyclic GMP; Cytidine; Cytosine Nucleotides; Depression, Chemical; Guanine; Guanine Nucleotides; Guanosine; Guanosine Triphosphate; Humans; Hypoxanthines; Inosine; Inosine Nucleotides; Mitosis; Skin; Thymine Nucleotides; Uracil Nucleotides | 1974 |
Human IMP dehydrogenase. Kinetics and regulatory properties.
Topics: Adenine; Adenosine; Carbon Radioisotopes; Cell Fractionation; Chromatography, DEAE-Cellulose; Chromatography, Paper; Cytosol; Female; Guanine; Guanosine; Humans; Inosine Nucleotides; Ketone Oxidoreductases; Kinetics; Mercaptopurine; Mitochondria; NAD; Placenta; Pregnancy; Purine Nucleotides; Pyrimidine Nucleotides; Structure-Activity Relationship; Ultracentrifugation | 1974 |
Improved methods for the study of drug effects on purine metabolism and their application to nebularine and 7-deazanebularine.
Topics: Adenine; Animals; Carbon Radioisotopes; Carcinoma, Ehrlich Tumor; Cells, Cultured; Chromatography, DEAE-Cellulose; Diphosphates; Fibroblasts; Guanine; Hypoxanthines; Inosine; Kinetics; Nucleotides; Oxidoreductases; Purine Nucleosides; Purines; Pyrimidines; Pyrroles; Ribonucleosides; Stimulation, Chemical; Structure-Activity Relationship | 1974 |
The purine DNA base cation and anion radicals: an e.s.r. study.
Topics: Adenine; Anions; DNA; Electron Spin Resonance Spectroscopy; Guanine; Ions; Photolysis | 1974 |
Reaction of methyl methanesulphonate with nucleic acids of fetal and newborn rats in vivo.
Topics: Adenine; Adenosine; Animals; Animals, Newborn; Autoradiography; Carbon Radioisotopes; Cytidine; DNA; Female; Fetus; Gestational Age; Guanine; Guanosine; Hydrolysis; Injections, Intraperitoneal; Maternal-Fetal Exchange; Mesylates; Methylation; Nucleic Acids; Pregnancy; Rats; Rats, Inbred Strains; RNA; Time Factors | 1974 |
Acinomycin D and purine transport in cultured rat hepatoma cells.
Topics: Adenine; Animals; Biological Transport, Active; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cells, Cultured; Clone Cells; Culture Media; Cycloheximide; Dactinomycin; Guanine; Guanosine; Hypoxanthines; Kinetics; Liver Neoplasms; Neoplasms, Experimental; Pentosyltransferases; Purines; Rats | 1974 |
A predictable modification of enzyme specificity. Selective alteration of DNA bases by metal ions to promote cleavage specificity by deoxyribonuclease.
Topics: Adenine; Alkaline Phosphatase; Animals; Binding Sites; Cattle; Copper; Cytosine; Deoxyribonucleases; DNA; Guanine; Magnesium; Mercury; Nucleic Acid Conformation; Phosphoric Diester Hydrolases; Thymine; Thymus Gland | 1974 |
Multiple mechanisms of regulation of purine biosynthesis de novo in intact tumor cells.
Topics: Adenine; Adenosine Triphosphate; Amides; Animals; Carbon Radioisotopes; Carcinoma, Ehrlich Tumor; Chromatography, Ion Exchange; Glycine; Guanine; Guanosine Triphosphate; Mice; Pentosephosphates; Pentosyltransferases; Phosphoric Acids; Purines; Ribose; Time Factors | 1974 |
Inhibition of the tetrahydrofolic acid cycle in HeLa and LDR cells by parainfluenza virus 1 (Sendai).
Topics: Adenine; Adsorption; Animals; Carbon Radioisotopes; Cells, Cultured; Chromatography, Thin Layer; Culture Media; Dansyl Compounds; DNA; Fibroblasts; Formates; Guanine; HeLa Cells; Humans; Mice; Nucleotides; Parainfluenza Virus 1, Human; RNA; Serine; Spectrophotometry, Ultraviolet; Tetrahydrofolates; Thymidine; Tritium | 1974 |
Regulation of serine transhydroxymethylase activity in Salmonella typhimurium.
Topics: Adenine; Aspartic Acid; Cell-Free System; Enzyme Repression; Glucose; Glycine; Guanine; Inosine; Lyases; Methionine; Mutation; Phosphoric Monoester Hydrolases; Salmonella typhimurium; Serine; Spectrophotometry; Tetrahydrofolates; Thymine; Transferases; Trimethoprim; Vitamin B 12 | 1974 |
Comparative rates of spontaneous mutation.
Topics: Adenine; Animals; Coliphages; Cytosine; DNA Replication; DNA, Bacterial; DNA, Viral; Drosophila; Escherichia coli; Genetics, Microbial; Guanine; Mutation; Neurospora; Salmonella typhimurium; Selection, Genetic; Thymine | 1969 |
Acid-soluble metabolites of adenine-2-14C-adenine-8-14C in 2,6-diaminopurine-sensitive and 2,6-diaminopurine-resistant L strain mouse cells.
Topics: Adenine; Adenine Nucleotides; Animals; Carbon Isotopes; Chromatography, Ion Exchange; Chromatography, Paper; Guanine; Guanine Nucleotides; L Cells; Mice; NAD; NADP; Nucleosides; Perchlorates; Purines; Urea; Uric Acid; Xanthines | 1968 |
[Production of deficient mutants of Candida guilliermondii with methanesulfonic acid ethyl ester].
Topics: Adenine; Amino Acids; Candida; Culture Media; Esters; Genetics, Microbial; Guanine; Mutagens; Mutation; Sulfonic Acids; Thymine; Uracil; Vitamin B Complex | 1968 |
[On the mechanism of action of 1-nitroso-3-nitro-1-methylguanidine during induced mutation. II. Products of the reaction of 1-nitroso-3-nitro-1-methylguanidine with nucleic bases, nucleosides, nucleosidephosphatesmand homopolyribonucleic acids].
Topics: Adenine; Adenine Nucleotides; Carbon Isotopes; Chromatography, Thin Layer; Guanidines; Guanine; Guanine Nucleotides; Hydrogen-Ion Concentration; Hypoxanthines; Methylation; Mutagens; Mutation; Nitroso Compounds; Nucleosides; Purines; Pyrimidines; Xanthines | 1968 |
High protective action against gamma radiation damage, by a tryptophan-ethanol mixture.
Topics: Adenine; Cytosine; DNA; Ethanol; Guanine; Radiation; Radiation Effects; Radiation-Protective Agents; Seeds; Thymine; Tryptophan; Uracil | 1972 |
Purine and pyrimidine absorption by the gut of the chiton, Cryptochiton stelleri.
Topics: Adenine; Aerobiosis; Anaerobiosis; Animals; Biological Transport, Active; Cytosine; Female; Guanine; Hypoxanthines; Intestinal Absorption; Male; Mollusca; Purines; Thymine; Uracil; Uric Acid | 1972 |
Chlorpromazine and purine transport in cultured human skin epithelial cells.
Topics: Adenine; Biological Transport; Carbon Radioisotopes; Cells, Cultured; Chlorpromazine; Chromatography, Paper; Depression, Chemical; Dose-Response Relationship, Drug; Epithelial Cells; Epithelium; Guanine; Humans; Hypoxanthines; Methods; Pentosyltransferases; Purines; Skin | 1974 |
Calculation of the circular dichroism of double-helical nucleic acids. 3. Dependence of the results on the choice of wave functions for purines and pyrimidines.
Topics: Adenine; Animals; Cattle; Circular Dichroism; Cytosine; Guanine; Mathematics; Methods; Nucleic Acids; Purines; Pyrimidines; Spectrum Analysis; Thymine | 1974 |
Calculations of the circular dichroism of double-helical nucleic acids. II. Effects involving n leads to pi transitions.
Topics: Adenine; Circular Dichroism; Cytosine; Energy Transfer; Guanine; Mathematics; Methods; Nucleic Acids; Optical Rotation; Purines; Pyrimidines; Spectrum Analysis; Thymine | 1974 |
Purine carbon-8 substituent as probe of the electronic structures of adenine and guanine. A computational study.
Topics: Adenine; Chemical Phenomena; Chemistry, Physical; Electrons; Guanine; Methods; Protons; Spectrophotometry, Ultraviolet | 1974 |
Changes of RNA base composition in nerve cells of monkeys subjected to visual discrimination and delayed alternation performance.
Topics: Adenine; Animals; Behavior, Animal; Cytosine; Discrimination Learning; Female; Form Perception; Frontal Lobe; Guanine; Hippocampus; Macaca; Male; Memory; Neurons; RNA; Temporal Lobe; Time Factors; Uracil | 1974 |
On the second portonation of adenine and guanine.
Topics: Adenine; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Guanine; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Mathematics; Molecular Conformation; Regression Analysis; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Sulfuric Acids | 1974 |
Transcription and translation of the sex message in the smut fungus Ustilago violacea. II. The effects of inhibitors.
Topics: Adenine; Amphotericin B; Basidiomycota; Carbon Radioisotopes; Chloramphenicol; Conjugation, Genetic; Cycloheximide; Dactinomycin; DNA Replication; Fungal Proteins; Guanine; Lysine; Protein Biosynthesis; Rifampin; RNA; RNA, Messenger; Sex; Transcription, Genetic; Tritium | 1974 |
The RNA base composition of Amoeba proteus, Amoeba discoides and their heterospecific hybrids.
Topics: Adenine; Amoeba; Analysis of Variance; Animals; Cellulose; Cytosine; Electrophoresis; Guanine; Hybridization, Genetic; Ribonucleases; RNA; Species Specificity; Spectrophotometry, Ultraviolet; Uracil | 1974 |
Chemical alterations induced in DNA and DNA components by the mutagenic agent azide.
Topics: Adenine; Azides; Binding Sites; Centrifugation, Density Gradient; Cytosine; Deoxyribonucleotides; DNA; Electrophoresis, Paper; Guanine; Hydrogen-Ion Concentration; Kinetics; Mutagens; Ribonucleotides; Spectrophotometry, Ultraviolet; Thymine | 1974 |
Comparative studies of the antineoplastic activity of 5-hydroxy-2-formylpyridine thiosemicarbazone and its seleno-semicarbazone, guanylhydrazone and semicarbazone analogs.
Topics: Adenine; Animals; Antineoplastic Agents; Carbon Radioisotopes; Cobalt; Cytidine; DNA, Neoplasm; Guanine; Hydrazones; Leucine; Ligands; Metals; Mice; Neoplasm Proteins; Phosphorus Radioisotopes; Pyridines; Ribonucleotide Reductases; RNA, Neoplasm; Sarcoma 180; Selenium; Semicarbazones; Sulfur; Thiosemicarbazones; Thymidine; Tritium | 1974 |
Carcinogenicity of N-methyl-N-nitrosourea: possible role of excision repair of O6-methylguanine from DNA.
Topics: Adenine; Animals; Brain; Brain Neoplasms; Carcinogens; DNA; DNA Repair; Female; Guanine; Kidney; Kidney Neoplasms; Liver; Methylation; Neoplasms, Experimental; Nitrosourea Compounds; Purines; Rats | 1974 |
Presence of heterodisperse nuclear RNA in a plant: Zea mays.
Topics: Adenine; Adenosine; Cell Nucleus; Cytosine; Guanine; Molecular Weight; Plants; RNA; Tritium; Uracil; Zea mays | 1974 |
Hydrogen exchange rate in C(8)H groups of purine residues as a tool for estimation of their pKa values in nucleic acids.
Topics: Adenine; Benzimidazoles; Calorimetry; DNA; Guanine; Hydrogen-Ion Concentration; Imidazoles; Isotope Labeling; Kinetics; Mathematics; Purines; Structure-Activity Relationship; Temperature; Thermodynamics; Time Factors; Tritium; Xanthines | 1974 |
Interaction between proflavine and double stranded polynucleotides.
Topics: Acridines; Adenine; Binding, Competitive; Circular Dichroism; Cytosine; Diamines; DNA; Fluorescence; Guanine; Inosine; Molecular Weight; Nucleic Acid Conformation; Polymers; Polynucleotides; Temperature; Uridine; Viscosity | 1974 |
Purine metabolism pathways in Drosophila cells grown "in vitro" : Phosphoribosyl transferase activities.
Topics: Adenine; Animals; Autoradiography; Aza Compounds; Carbon Radioisotopes; Cell Line; Cells, Cultured; Drosophila; Drug Resistance; Embryo, Nonmammalian; Guanine; Hypoxanthines; Mutation; Pentosyltransferases | 1974 |
[Scury and purine catabolism].
Topics: Adenine; Allantoin; Animals; Ascorbic Acid Deficiency; Guanine; Guinea Pigs; Purines; Scurvy; Stimulation, Chemical; Urate Oxidase; Urea; Uric Acid; Xanthine Oxidase | 1974 |
Hypoxanthine-guanine phosphoribosyltransferase and adenine phosphoribosyltransferase from Plasmodium chabaudi, purification and properties.
Topics: Adenine; Guanine; Hypoxanthines; Isoelectric Focusing; Isoenzymes; Mercaptopurine; Molecular Weight; Pentosyltransferases; Plasmodium; Thioguanine | 1974 |
Inhibitors of inosinate dehydrogenase activity in Ehrlich ascites tumor cells in vitro.
Topics: Adenine; Animals; Carbon Radioisotopes; Carcinoma, Ehrlich Tumor; Cells, Cultured; Chromatography, DEAE-Cellulose; Chromatography, Paper; Guanine; Guanosine; Guanosine Triphosphate; Hypoxanthines; Inosine; Leukemia L1210; Mice; Mycophenolic Acid; Nucleotides; Oxidoreductases; Purines; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 1974 |
Incorporation of tritium from tritiated water into nucleic acids of Oryzias latipes eggs.
Topics: Adenine; Animals; Cyprinidae; Cytosine; DNA; Female; Guanine; Ovum; Radiation Dosage; RNA; Thymine; Time Factors; Tritium; Water Pollution, Radioactive | 1974 |
Precursor-product relationships between nucleotides and RNA during differentiation in Dictyostelium discoideum.
Topics: Adenine; Adenosine Triphosphate; Carbon Radioisotopes; Chromatography, Thin Layer; Guanine; Guanine Nucleotides; Guanosine Triphosphate; Models, Biological; Morphogenesis; Myxomycetes; Nucleotides; RNA; Uracil; Uracil Nucleotides | 1974 |
Nucleotide sequencing of DNA: preliminary characterization of the products of specific cleavages at guanine, cytosine, or adenine residues (bacteriophage M13-ribosubstitution-DNA polymerase I-electrophoresis-two-dimensional fingerprinting).
Topics: Adenine; Adenosine Triphosphate; Autoradiography; Bacteriophages; Base Sequence; Cytosine; Cytosine Nucleotides; DNA Nucleotidyltransferases; DNA, Viral; Electrophoresis; Guanine; Methods; Phosphorus Isotopes; Templates, Genetic; Thymine Nucleotides | 1972 |
Base composition of normal and megaloblastic bone marrow DNA.
Topics: Adenine; Anemia, Macrocytic; Bone Marrow; Bone Marrow Cells; Cytidine; Cytosine; DNA; Folic Acid Deficiency; Guanine; Humans; Nucleotides; Thymine; Tritium; Vitamin B 12 Deficiency | 1972 |
Virulent bacteriophage infection of Rhizobium leguminosarum.
Topics: Adenine; Bacteriophages; Carbon Isotopes; Cell-Free System; Cytosine; DNA, Bacterial; DNA, Viral; Guanine; Methyltransferases; Microscopy, Electron; Molecular Weight; Nucleotidases; Phosphotransferases; Rhizobium; RNA, Bacterial; Tetrahydrofolate Dehydrogenase; Thymidine; Thymine; Thymine Nucleotides; Uracil; Viral Proteins; Virus Replication | 1972 |
Identification of the enzymatic pathways of nucleotide metabolism in human lymphocytes and leukemia cells.
Topics: Adenine; Adenine Nucleotides; Adenosine; Aminohydrolases; Animals; Cell Fractionation; Cell Line; Child; Cytidine; Guanine; Guanine Nucleotides; Humans; Leukemia, Lymphoid; Lymphocytes; Male; Nucleotides; Pentosyltransferases; Phosphotransferases; Purine Nucleotides; Purines; Pyrimidines; Sarcoma 180; Xanthine Oxidase | 1973 |
Leukocyte purine phosphoribosyltransferases in human leukemias sensitive and resistant to 6-thiopurines.
Topics: Adenine; Adolescent; Adult; Aged; Antimetabolites; Drug Resistance; Female; Guanine; Humans; Hypoxanthines; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Male; Mercaptopurine; Mutation; Pentosyltransferases; Remission, Spontaneous; Thioguanine | 1973 |
Persistence of O6-ethylguanine in rat-brain DNA: correlation with nervous system-specific carcinogenesis by ethylnitrosourea.
Topics: Adenine; Alkylation; Animals; Animals, Newborn; Brain; Carbon Radioisotopes; Carcinogens; Cell Transformation, Neoplastic; Chromatography, Gel; DNA; DNA Replication; Guanine; Kinetics; Liver; Nitrosourea Compounds; Purine Nucleosides; Rats | 1974 |
Mechanisms of resistance to 6-thiopurines in human leukemia.
Topics: Adenine; Alkaline Phosphatase; Drug Resistance; Guanine; Humans; Hypoxanthines; Leukemia; Leukemia, Lymphoid; Lymphocytes; Mercaptopurine; Pentosyltransferases; Thioguanine | 1974 |
Purine and pyrimidine pool sizes and purine base utilization in human lymphocytes and cultured lymphoblasts.
Topics: Adenine; Adenine Nucleotides; Burkitt Lymphoma; Carbon Radioisotopes; Cell Line; Centrifugation, Density Gradient; Chromatography, Ion Exchange; Guanine; Guanine Nucleotides; Humans; Hypoxanthines; Leukemia, Myeloid, Acute; Lymphocytes; Pentosyltransferases; Pressure; Purines; Pyrimidines; Ribonucleotides | 1974 |
Reactions between organic nitroxyl free radicals and radiation-induced transients in the DNA bases.
Topics: Adenine; Chemical Phenomena; Chemistry; Cyclic N-Oxides; Cytosine; Free Radicals; Guanine; Nitrogen; Nitrous Oxide; Oxygen; Purines; Pyrimidines; Radiation Effects; Radiation-Sensitizing Agents; Spectrum Analysis; Thymine | 1972 |
DNA repair with purines and pyrimidines in radiation- and carcinogen-damaged normal and xeroderma pigmentosum human cells.
Topics: Adenine; Carcinogens; Carmustine; Cells, Cultured; Deoxyadenosines; DNA; DNA Repair; DNA, Neoplasm; Guanidines; Guanine; HeLa Cells; Humans; Hydroxyurea; Hypoxanthines; Nitroso Compounds; Quinolines; Radiation Effects; Skin; Ultraviolet Rays; Xeroderma Pigmentosum | 1973 |
Separation of nucleotides, nucleosides and bases of DNA with cation exchange columns.
Topics: Adenine; Animals; Cattle; Chromatography, Ion Exchange; Cytosine; Cytosine Nucleotides; Deoxyadenosines; Deoxycytidine; Deoxyribonucleases; Deoxyribonucleosides; Deoxyribonucleotides; DNA; Evaluation Studies as Topic; Formates; Guanine; Hydrolysis; Methods; Purines; Pyrimidinones; Quaternary Ammonium Compounds; Spectrophotometry, Ultraviolet; Thymidine; Thymine; Thymine Nucleotides; Thymus Gland | 1973 |
Adenosine aminohydrolase from Halobacterium cutirubrum.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Aminohydrolases; Ammonium Sulfate; Chemical Precipitation; Chromatography, Gel; Cytidine; Deoxyadenosines; Dextrans; Enzyme Activation; Glycols; Guanine; Halobacterium; Hydrogen-Ion Concentration; Kinetics; Molecular Weight; Nucleosides; Polyethylenes; Sodium Chloride; Structure-Activity Relationship | 1973 |
[Proceedings: The optimal blood conserve (author's transl)].
Topics: Adenine; Blood; Blood Preservation; Blood Transfusion; Blood Transfusion, Autologous; Citrates; Diphosphoglyceric Acids; Erythrocyte Aging; Erythrocytes; Freeze Drying; Glucose; Guanine; Humans; Hydrogen-Ion Concentration; Oxygen Consumption; Potassium; Time Factors | 1973 |
Base ratio determination using unpurified DNA.
Topics: Adenine; Adenine Nucleotides; Animals; Cattle; Chromatography, Ion Exchange; Clostridium; DNA; Escherichia coli; Guanine; Guanine Nucleotides; Hydrolysis; Liver; Male; Micrococcus; Nucleotides; Plants; Rats; Rhizobium; Ribonucleases; Salmon; Spectrophotometry; Spermatozoa; Thymus Gland; Ultraviolet Rays | 1972 |
Physiological factors in the regulation of alkaline phosphatase synthesis in Escherichia coli.
Topics: Adenine; Alkaline Phosphatase; Bacterial Proteins; Carbon Isotopes; Culture Media; Enzyme Induction; Escherichia coli; Genetics, Microbial; Guanine; Leucine; Mutation; Nucleotides; Phosphates; Phosphorus Isotopes; Thymine; Uracil | 1972 |
The mitochondrial genome of wild-type yeast cells. II. Investigations on the compositional heterogeneity of mitochondrial DNA.
Topics: Adenine; Base Sequence; Centrifugation, Density Gradient; Chromatography; Cytosine; Deoxyribonucleases; DNA; Guanine; Hydroxyapatites; Mitochondria; Molecular Weight; Nucleotides; Saccharomyces; Saccharomyces cerevisiae; Temperature; Thymine | 1972 |
The mitochondrial genome of wild-type yeast cells. 3. The pyrimidine tracts of mitochondrial DNA.
Topics: Adenine; Base Sequence; Chromatography, DEAE-Cellulose; Cytosine; DNA; Guanine; Mitochondria; Pyrimidines; Saccharomyces; Saccharomyces cerevisiae; Thymine | 1972 |
Purine phosphoribosyltransferases of Salmonella typhimurium.
Topics: Adenine; Carbon Isotopes; Cell-Free System; Chromatography, Thin Layer; Culture Media; Guanine; Guanine Nucleotides; Hypoxanthines; Inosine Nucleotides; Mutation; Pentosyltransferases; Salmonella typhimurium; Transduction, Genetic; Xanthines | 1972 |
Genetic separation of hypoxanthine and guanine-xanthine phosphoribosyltransferase activities by deletion mutations in Salmonella typhimurium.
Topics: Adenine; Azaguanine; Carbon Isotopes; Cell-Free System; Chromosome Mapping; Culture Media; Drug Resistance, Microbial; Genes, Regulator; Genetics, Microbial; Guanine; Guanine Nucleotides; Hypoxanthines; Mutation; Oxidoreductases; Pentosyltransferases; Salmonella typhimurium; Xanthines | 1972 |
Methylation pattern of lambda deoxyribonucleic acid.
Topics: Adenine; Autoradiography; Base Sequence; Carbon Isotopes; Centrifugation, Density Gradient; Chromatography, Thin Layer; Coliphages; Cytosine; DNA, Single-Stranded; DNA, Viral; Escherichia coli; Guanine; Methionine; Methylation; Molecular Weight; Nucleic Acid Denaturation; Nucleotides; Phosphorus Isotopes; Tritium | 1972 |
The control of ribonucleic acid synthesis in bacteria. Polymerization rates for ribonucleic acids in amino acid-starved relaxed and stringent auxotrophs of Escherichia coli.
Topics: Adenine; Amino Acids; Carbon Isotopes; Chloramphenicol; Chromatography, Ion Exchange; DNA, Bacterial; Escherichia coli; Guanine; Nucleic Acid Hybridization; Polymers; Purines; Rifampin; RNA, Bacterial; Trimethoprim; Tritium; Uracil | 1972 |
High resolution nuclear magnetic resonance study of base pairing in the native and denaturated conformers of transfer RNA Leu 3 .
Topics: Adenine; Base Sequence; Binding Sites; Cytosine; Guanine; Leucine; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Nucleic Acid Denaturation; RNA, Transfer; Saccharomyces cerevisiae; Uracil | 1973 |
Chlamydospore production and germ-tube formation by auxotrophs of Candida albicans.
Topics: Adenine; Agar; Amino Acids; Aminobutyrates; Candida albicans; Culture Media; Cysteine; Guanine; Humans; Immune Sera; Methionine; Mutation; Spores; Spores, Fungal; Stereoisomerism; Surface-Active Agents; Zea mays | 1973 |
Investigation of exchangeable protons and the extent of base pairings in yeast phenylalanine transfer RNA by high resolution nuclear magnetic resonance.
Topics: Adenine; Base Sequence; Binding Sites; Carbon Isotopes; Cytosine; Guanine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Models, Biological; Nucleic Acid Conformation; Phenylalanine; Protons; RNA, Transfer; Saccharomyces cerevisiae; Temperature; Tritium | 1972 |
The extent of base pairing in 5 s RNA. Yeast 5 s RNA.
Topics: Adenine; Base Sequence; Cytosine; Endonucleases; Guanine; Magnesium; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; RNA, Ribosomal; RNA, Transfer; Saccharomyces cerevisiae; Temperature; Uridine | 1972 |
The relationship between mismatched base pairs and the thermal stability of DNA duplexes. I. Effects of depurination and chain scission.
Topics: Adenine; Base Sequence; Binding Sites; Carbon Isotopes; Chromatography; Chromatography, Gel; Chromatography, Thin Layer; DNA, Bacterial; Drug Stability; Escherichia coli; Filtration; Guanine; Hot Temperature; Hydroxyapatites; Kinetics; Nucleic Acid Denaturation; Nucleic Acid Hybridization; Nucleic Acid Renaturation; Oligonucleotides | 1973 |
Genetics of resistance to 4-aminopyrazolo-(3,4-d)-pyrimidine in Saccharomyces cerevisiae.
Topics: Adenine; Aza Compounds; Chromosome Mapping; Crosses, Genetic; Drug Resistance, Microbial; Genes, Dominant; Genes, Recessive; Genetic Linkage; Genetics, Microbial; Guanine; Hypoxanthines; Mercaptopurine; Methylation; Purines; Pyrazoles; Pyrimidines; Saccharomyces cerevisiae; Suppression, Genetic | 1973 |
Purine-pyrimidine requirement for ribonucleic acid synthesis in an Escherichia coli mutant defective in potassium accumulation.
Topics: Adenine; Biological Transport; Carbon Isotopes; Cell Count; Cell Division; Chromatography, Thin Layer; Cytosine; Densitometry; Escherichia coli; Guanine; Isotope Labeling; Mutation; Potassium; Ribonucleotides; RNA, Bacterial; Sodium; Time Factors; Tritium; Uracil | 1973 |
Assignment of the low field proton nuclear magnetic resonance spectrum of yeast phenylalanine transfer RNA to specific base pairs.
Topics: Adenine; Base Sequence; Chromatography; Cytosine; Guanine; Magnesium; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Phenylalanine; RNA, Transfer; Saccharomyces cerevisiae; Uracil | 1973 |
Raman studies of nucleic acids. X. Conformational structures of Escherichia coli transfer RNAs in aqueous solution.
Topics: Adenine; Arginine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Esters; Glutamates; Guanine; Lasers; Magnesium; Methionine; Microchemistry; Molecular Weight; Nucleic Acid Conformation; Phenylalanine; Phosphates; RNA, Bacterial; RNA, Transfer; Solubility; Spectrum Analysis; Temperature; Uridine; Valine; Water | 1973 |
Yeast killer mutants with altered double-stranded ribonucleic acid.
Topics: Adenine; Centrifugation; Chemical Precipitation; Chromatography, Paper; Cycloheximide; Cytosine; Electrophoresis, Polyacrylamide Gel; Guanine; Molecular Weight; Mutation; Mycotoxins; Phenotype; Phosphorus Radioisotopes; RNA; Saccharomyces cerevisiae; Temperature; Uracil | 1974 |
Control of serine transhydroxymethylase synthesis in Escherichia coli K12.
Topics: Adenine; Culture Media; Escherichia coli; Formates; Glycine; Guanine; Histidine; Isoleucine; Methionine; Mutation; Serine; Thymidine; Transferases; Tritium; Valine | 1974 |
Alterations in structure and function of transfer ribonucleic acid on chemical methylation.
Topics: Adenine; Carbon Radioisotopes; Chemical Phenomena; Chemistry; Circular Dichroism; Cytosine; Guanine; Methylation; Peptide Biosynthesis; Phenylalanine; Poly U; Purines; Ribonucleotides; RNA, Transfer; Saccharomyces cerevisiae; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Sulfuric Acids; Temperature; Transfer RNA Aminoacylation; Tritium; Viscosity | 1974 |
The enzymatic release of O6-methylguanine and 3-methyladenine from DNA reacted with the carcinogen N-methyl-N-nitrosourea.
Topics: Adenine; Catalysis; Chemical Phenomena; Chemistry; Chromatography; Chromatography, Paper; Chromatography, Thin Layer; Deoxyribonucleases; DNA, Bacterial; Endonucleases; Escherichia coli; Guanine; Nitrosourea Compounds; Sulfates | 1974 |
Effects of methylation on the stability of nucleic acid conformations: studies at the monomer level.
Topics: Adenine; Calorimetry; Chromatography, Thin Layer; Computers; Cytosine; Deuterium; DNA; DNA, Bacterial; Escherichia coli; Fourier Analysis; Guanine; Kinetics; Magnetic Resonance Spectroscopy; Mathematics; Methylation; Models, Biological; Nitrogen Isotopes; Nucleic Acid Conformation; RNA; Temperature; Thermodynamics | 1974 |
Investigation of the secondary structure of Escherichia coli 5 S RNA by high-resolution nuclear magnetic resonance.
Topics: Adenine; Base Sequence; Binding Sites; Cytosine; Deuterium; Escherichia coli; Guanine; Magnesium; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; RNA, Bacterial; Temperature; Thermodynamics; Uracil | 1974 |
Reactions of polycyclic hydrocarbon epoxides with RNA and polyribonucleotides.
Topics: Adenine; Adenine Nucleotides; Alkaline Phosphatase; Alkylation; Benz(a)Anthracenes; Binding Sites; Chromatography, Ion Exchange; Chromatography, Thin Layer; Guanine; Guanine Nucleotides; Hydrolysis; Oxides; Polynucleotides; RNA; Saccharomyces cerevisiae; Spectrophotometry, Ultraviolet; Tritium | 1974 |
Dinucleotide sequences in the regions of T7 DNA coding for termination of early transcription.
Topics: Adenine; Base Sequence; Binding Sites; Coliphages; Cytosine; DNA-Directed RNA Polymerases; DNA, Single-Stranded; DNA, Viral; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Genetic Code; Genotype; Guanine; Nucleic Acid Conformation; Nucleic Acid Hybridization; RNA, Viral; Templates, Genetic; Transcription, Genetic; Ultracentrifugation | 1974 |
The metabolism of starch, glucose, amino acids, purines, pyrimidines and bacteria by the rumen ciliate Entodinium simplex.
Topics: Adenine; Amino Acids; Anaerobiosis; Animals; Bacteria; Bicarbonates; Carbon Isotopes; Ciliophora; Cytosine; Galactose; Glucose; Glutamates; Guanine; Klebsiella; Leucine; Nucleic Acids; Polysaccharides; Protein Biosynthesis; Proteus mirabilis; Purines; Pyrimidines; Rumen; Starch; Uracil | 1972 |
Fractionation of DNA from Bacillus subtilis and its transforming activity for various markers.
Topics: Adenine; Bacillus subtilis; Base Sequence; Cell Fractionation; Centrifugation, Density Gradient; Centrifugation, Zonal; Chromatography, Gel; Chromatography, Ion Exchange; Cytosine; DNA, Bacterial; Guanine; Leucine; Methionine; Molecular Weight; Phosphorus Isotopes; Spectrophotometry; Thymidine; Transformation, Genetic; Tritium | 1972 |
Double strandedness of ribonucleic acid of bovine ephemeral fever virus.
Topics: Adenine; Animals; Cattle; Cattle Diseases; Cells, Cultured; Centrifugation, Density Gradient; Cytidine; Fever; Guanine; Hot Temperature; Lithium; Microscopy, Electron; Nucleotides; Phosphates; Ribonucleases; RNA, Viral; Uracil; Uridine; Viruses, Unclassified | 1972 |
Effect of adenine on the riboflavin-sensitized photoreaction. 3. Effect of adenine on the photodegradation of guanine residues in deoxyribonucleic acid in the presence of riboflavin.
Topics: Adenine; Air; Bacillus subtilis; Chromatography; DNA, Bacterial; Guanine; Nitrogen; Nucleotides; Photochemistry; Radiation Effects; Riboflavin; Spectrum Analysis | 1972 |
[Effect of benziodaron on purine metabolism in gout patients and healthy subjects].
Topics: Adenine; Benzofurans; Gout; Guanine; Humans; Hypoxanthines; Iodobenzoates; Male; Pentosyltransferases; Purines; Uricosuric Agents | 1972 |
Evidence for post-transcriptional stabilization of ribosomal precursor ribonucleic acid by phenobarbital.
Topics: Adenine; Animals; Carbon Isotopes; Cell Nucleolus; Cell Nucleus; Centrifugation, Density Gradient; Chromatography; DNA; Drug Stability; Guanine; Liver; Male; Microsomes, Liver; Orotic Acid; Phenobarbital; Rats; RNA, Ribosomal; Sucrose; Transcription, Genetic; Tritium; Uracil Nucleotides | 1972 |
Stimulatory effects of purines on flavinogenesis by non-growing cell of Erethecium ashbyii.
Topics: Adenine; Ascomycota; Chromatography, Ion Exchange; Guanine; Hypoxanthines; Purines; Riboflavin; Spectrophotometry, Ultraviolet; Stimulation, Chemical; Xanthines | 1972 |
[On neighbourly relations in chemical mutagenesis].
Topics: Adenine; Cytosine; Guanine; Hydroxylamines; Mutagens; Nucleic Acids; Thymine; Uracil | 1972 |
[Purine transport in Pichia guilliermondii yeasts].
Topics: Adenine; Azides; Biological Transport; Cells, Cultured; Culture Media; Cycloheximide; Guanine; Guanosine; Hypoxanthines; Kinetics; Membrane Transport Proteins; Purines; Sodium; Spectrophotometry; Uric Acid; Xanthines; Yeasts | 1972 |
Communication between normal and enzyme deficient cells in tissue culture.
Topics: Adenine; Animals; Autoradiography; Cells, Cultured; Contact Inhibition; Cricetinae; Fibroblasts; Glucosephosphate Dehydrogenase; Guanine; HeLa Cells; Humans; Hypoxanthines; Kidney; L Cells; Lesch-Nyhan Syndrome; Mice; Mutation; Pentosyltransferases; Phenotype; Species Specificity; Sulfhydryl Compounds; Tritium | 1972 |
Methylation of ribonucleic acid by the carcinogens dimethyl sulphate, N-methyl-N-nitrosourea and N-methyl-N'-nitro-N-nitrosoguanidine. Comparisons of chemical analyses at the nucleoside and base levels.
Topics: Adenine; Animals; Carbon Isotopes; Carcinogens; Chromatography, Ion Exchange; Guanine; Guanosine; Hydrolysis; Methylation; Nitrosoguanidines; Nitrosourea Compounds; Nucleic Acid Denaturation; Nucleosides; Pyrimidine Nucleotides; Rabbits; RNA; Sulfuric Acids; Uracil | 1972 |
Inhibitors of nucleoside and nucleotide metabolism.
Topics: Adenine; Adenine Nucleotides; Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Erythrocytes; Guanine; Humans; Hypoxanthines; Mercaptopurine; Neoplasms; Nucleosides; Nucleotides; Pentosyltransferases; Phosphotransferases; Purines; Pyrimidines; Thioguanine | 1972 |
[The demonstration of hypoxanthine-guanine phosphoribosyl transferase enzyme protein in Lesch-Nyhan Syndrome].
Topics: Adenine; Erythrocytes; Guanine; Humans; Hypoxanthines; Lesch-Nyhan Syndrome; Phosphotransferases; Ribosomes | 1973 |
Pathways of nucleotide metabolism in Schistosoma mansoni. 3. Identification of enzymes in cell-free extracts.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Aminohydrolases; Animals; Carbon Isotopes; Cell-Free System; Chromatography, Thin Layer; Creatine Kinase; Cytidine; Freeze Drying; Guanine; Hypoxanthines; Mice; Mice, Inbred Strains; Nucleotides; Pentosyltransferases; Phosphotransferases; Purines; Schistosoma mansoni; Time Factors | 1973 |
Photoalkylation of purines in DNA.
Topics: Adenine; Alkylation; Chromatography; DNA; Guanine; Photochemistry; Purines; Radiation Effects; Ultraviolet Rays | 1973 |
Dietary-induced variation of hypoxanthine-guanine phosphoribosyl transferase activity in patients with the Lesch-Nyhan syndrome.
Topics: Adenine; Carbon Isotopes; Diet; Enzyme Activation; Guanine; Half-Life; Humans; Hypoxanthines; Lesch-Nyhan Syndrome; Pentosyltransferases; Purines | 1973 |
The uptake of purines by rat brain in vivo and in vitro.
Topics: Adenine; Aging; Animals; Biological Transport; Brain; Carbon Isotopes; Chromatography; Dinitrophenols; Female; Glucose; Guanine; Guanosine; Hypoxanthines; In Vitro Techniques; Inosine; Male; Ouabain; Purines; Rats; RNA; Uridine | 1973 |
Alkylation of rat brain nucleic acids by N-methyl-N-nitrosourea and methyl methanesulphonate.
Topics: Adenine; Alkylation; Animals; Brain; Brain Chemistry; Carbon Isotopes; Cytoplasm; DNA; Female; Guanine; Hydrolysis; Ileum; Kidney; Liver; Methylation; Nitrosourea Compounds; Nucleic Acids; Rats; RNA; RNA, Transfer; Sulfonic Acids | 1973 |
Adenine, hypoxanthine and guanine metabolism in fibroblasts from normal individuals and from patients with hypoxanthine phosphoribosyltransferase deficiency.
Topics: Adenine; Adenine Nucleotides; Carbon Isotopes; Cells, Cultured; Fibroblasts; Guanine; Humans; Hypoxanthines; Inosine Nucleotides; Kinetics; Lesch-Nyhan Syndrome; Models, Biological; Pentosephosphates; Pentosyltransferases; Time Factors | 1973 |
Quantum-mechanical studies of environmental effects of biomolecules. II. Hydration sites in purines and pyrimidines.
Topics: Adenine; Chemical Phenomena; Chemistry; Cytosine; Guanine; Purines; Pyrimidines; Quantum Theory; Thymine | 1973 |
Free energy of imperfect nucleic acid helices. II. Small hairpin loops.
Topics: Adenine; Base Sequence; Binding Sites; Guanine; Hot Temperature; Molecular Weight; Nucleic Acid Conformation; Oligonucleotides; RNA; Thermodynamics; Uracil | 1973 |
The influx of purines and pyrimidines across the brush border of Hymenolepis diminuta.
Topics: Absorption; Adenine; Animals; Binding Sites; Bromouracil; Carbon Isotopes; Cestoda; Culture Media; Guanine; Hymenolepiasis; Hypoxanthines; Purines; Pyrimidines; Thymine; Uracil | 1973 |
Electron beam excitation and damage of biological molecules; its implications for specimen damage in electron microscopy.
Topics: Acridines; Adenine; Cytosine; DNA; Dose-Response Relationship, Radiation; Electrons; Guanine; Microscopy, Electron, Scanning; Polynucleotides; Radiation Effects; Ribosomes; Thymine; Uracil | 1973 |
Quantitative changes in the content of nuclei acid bases and their derivatives in a culture of Penicillium sizowi.
Topics: Adenine; Cell-Free System; Chromatography, Ion Exchange; Chromatography, Thin Layer; Cytosine; Densitometry; Enzymes; Filtration; Guanine; Penicillium; Ribonucleosides; Ribonucleotides; Uracil | 1973 |
The effect of urethan on the incorporation of thymidine-3H into DNA and the activities of some enzymes required for DNA biosynthesis in rat regenerating liver.
Topics: Adenine; Alcohol Oxidoreductases; Animals; Depression, Chemical; DNA; DNA Nucleotidyltransferases; DNA Replication; Enzyme Induction; Guanine; Hepatectomy; Hypoxanthines; Liver; Liver Regeneration; Male; Pentosyltransferases; Rats; Ribonucleosides; Ribonucleotides; Thymidine; Thymidine Kinase; Time Factors; Tritium; Urethane | 1973 |
A rapid column chromatographic procedure for the assay of RNA methyltransferases.
Topics: Adenine; Chromatography, Ion Exchange; Evaluation Studies as Topic; Guanine; Methods; Methylation; Methyltransferases; RNA; Spectrophotometry, Ultraviolet; Time Factors; Tritium | 1973 |
Biosynthesis of riboflavin. The structure of the purine precursor.
Topics: Adenine; Alloxan; Carbon Isotopes; Culture Media; Darkness; Enterobacter; Guanine; Hypoxanthines; Mutation; Nucleosides; Purines; Riboflavin; Species Specificity; Xanthines | 1973 |
Nucleotide conformations in codon-anticodon interactions.
Topics: Adenine; Base Sequence; Computers; Guanine; Hypoxanthines; Models, Structural; Nucleic Acid Conformation; Pyrimidines; RNA; Uracil | 1973 |
Absence of demonstrable linkage of human genes for enzymes of the purine and pyrimidine salvage pathways in human-mouse somatic cell hybrids.
Topics: Adenine; Adenosine; Alkaline Phosphatase; Aminohydrolases; Animals; Cell Line; Cytidine; Diploidy; Electrophoresis; Fibroblasts; Guanine; HeLa Cells; Humans; Hybrid Cells; Hypoxanthines; Isoelectric Focusing; L Cells; Mice; Nucleotidases; Pentosyltransferases; Phosphotransferases; Purines; Pyrimidines; Thymidine Kinase | 1973 |
The content of 5-methylcytosine in animal DNA: the species and tissue specificity.
Topics: Adenine; Amphibians; Animals; Anura; Birds; Brain Chemistry; Chromatography, Paper; Chromatography, Thin Layer; Cytosine; DNA; Echinodermata; Fishes; Guanine; Kidney; Liver; Lung; Male; Methylation; Muscles; Rats; Species Specificity; Spermatozoa; Spleen; Thymine | 1973 |
Effects of elevated intracellular ATP and GTP concentrations on purine ribonucleotide synthesis and interconversion.
Topics: Adenine; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Guanine; Guanine Nucleotides; Hypoxanthines; Lyases; Nucleotides; Pentosyltransferases; Phosphotransferases; Purine Nucleotides; Time Factors | 1973 |
Factors effecting the initiation of mitosis in Allomyces neo-moniliformis.
Topics: Adenine; Calcium; Fungi; Glucose; Guanine; Magnesium; Mannitol; Membrane Potentials; Mitosis; Potassium; Ribose; Sodium; Time Factors | 1973 |
Ribosomes and ribonucleic acids of Coxiella burneti.
Topics: Adenine; Autoradiography; Chromatography, Thin Layer; Coxiella; Cytosine; Electrophoresis, Polyacrylamide Gel; Guanine; Magnesium; Microscopy, Electron; Molecular Weight; Ribosomes; RNA, Bacterial; RNA, Ribosomal; Spectrophotometry, Ultraviolet; Ultracentrifugation; Uracil | 1973 |
Molecular orbital (CNDO/2 and MINDO) calculations on protonated deoxyribonucleic acid bases. The effects of base protonation on intermolecular interactions.
Topics: Adenine; Cytosine; DNA; Electrochemistry; Electron Transport; Guanine; Hydrogen-Ion Concentration; Molecular Conformation; Molecular Weight; Protons; Structure-Activity Relationship; Thymine | 1973 |
Chlorination studies. IV. The reaction of aqueous hypochlorous acid with pyrimidine and purine bases.
Topics: Adenine; Bromouracil; Caffeine; Chemical Phenomena; Chemistry; Guanine; Mass Spectrometry; Purines; Pyrimidines; Sodium Hypochlorite; Spectrophotometry, Ultraviolet; Theophylline; Thymine; Uracil; Xanthines | 1973 |
The sites of action of allopurinol in Crithidia fasciculata.
Topics: Adenine; Allopurinol; Animals; Carbon Radioisotopes; Cell-Free System; Chemical Phenomena; Chemistry; Chromatography, Paper; Colorimetry; Cytosine; Dose-Response Relationship, Drug; Eukaryota; Folic Acid; Guanine; Hypoxanthines; Orotic Acid; Pentosyltransferases; Pterins; Spectrophotometry; Uracil; Xanthines | 1973 |
[Microelectrophoretic study of the characteristics of RNA metabolism in individual neurons of cultivated nerve tissue].
Topics: Adenine; Animals; Culture Techniques; Cytosine; Electrophoresis; Ganglia, Spinal; Guanine; Neurons; Rabbits; RNA; Uracil | 1973 |
[Methylation of DNA cytosine in lymphocytes of healthy subjects and in chronic lympholeukosis].
Topics: Adenine; Carbon Radioisotopes; Cytosine; DNA; DNA, Neoplasm; Guanine; Humans; Leukemia, Lymphoid; Lymphocytes; Methionine; Methylation; Thymine | 1973 |
[Adenosine monophosphate salvage synthesis in Plasmodium chabaudi].
Topics: Adenine; Adenosine Monophosphate; Aminohydrolases; Animals; Carbon Radioisotopes; Clinical Enzyme Tests; Glucokinase; Guanine; Hypoxanthines; Malaria; Mice; Pentosyltransferases; Peptide Synthases; Plasmodium; Purine Nucleotides | 1973 |
Development of defined media for growth of Trypanosoma brucei sspp.
Topics: Adenine; Adenosine; Bicarbonates; Buffers; Cell Count; Citrates; Culture Media; Glucosamine; Guanine; Guanosine; Hydrogen-Ion Concentration; Proline; Succinates; Trypanosoma brucei brucei | 1973 |
Purine salvage in spleen cells.
Topics: Adenine; Animals; Carbon Radioisotopes; Deoxyribose; Female; Guanine; Guanine Nucleotides; Humans; Hypoxanthines; Kinetics; Mice; Mice, Inbred Strains; Nucleotidases; Organ Specificity; Pentosephosphates; Pentosyltransferases; Purine Nucleotides; Purines; Species Specificity; Spleen; Time Factors; Tritium | 1973 |
Purine nucleotide synthesis, interconversion and catabolism in human leukocytes.
Topics: Adenine; Age Factors; Cells, Cultured; Computers; Drug Stability; Evaluation Studies as Topic; Guanine; Humans; Hypoxanthines; Lesch-Nyhan Syndrome; Leukocytes; Methods; Pentosyltransferases; Purine Nucleotides; Sex Factors; Temperature | 1973 |
Purine metabolism in intact erythrocytes from controls and HG-PRT deficient individuals.
Topics: Adenine; Adenosine; Carbon Radioisotopes; Cell Membrane; Erythrocytes; Guanine; Guanine Nucleotides; Humans; Hypoxanthines; Inosine Nucleotides; Kinetics; Pentosephosphates; Pentosyltransferases; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Time Factors | 1973 |
Regulation of de novo purine synthesis in the Lesch-Nyhan syndrome.
Topics: Adenine; Adult; Ammonia; Carbon Radioisotopes; Cell-Free System; Cells, Cultured; Child, Preschool; Female; Glutamine; Guanine; Humans; Hypoxanthines; Lesch-Nyhan Syndrome; Lymphocytes; Male; Pentosephosphates; Pentosyltransferases; Transaminases | 1973 |
Methylation of DNA by 3H-14C-methyl-labelled N-methyl-N-nitrosourea--evidence for transfer of the intact methyl group.
Topics: Adenine; Animals; Carbon Radioisotopes; Carcinogens; Chromatography; Cytidine; DNA; Guanine; Hydrolysis; Male; Methane; Methylation; Nitrosourea Compounds; Salmon; Spectrophotometry, Ultraviolet; Spermatozoa; Thymidine; Tritium | 1973 |
A kinetic analysis of purine nucleotide synthesis and interconversion in intact Ehrlich ascites tumor cells.
Topics: Adenine; Adenosine Triphosphate; Animals; Carbon Radioisotopes; Carcinoma, Ehrlich Tumor; Cells, Cultured; Chromatography, Thin Layer; Guanine; Guanosine Triphosphate; Hypoxanthines; Kinetics; Mice; Models, Biological; Purine Nucleotides | 1973 |
[Changes in brain cell genome structure under the influence of dexamethasone].
Topics: Adenine; Animals; Brain; Brain Chemistry; Cattle; Cell Nucleolus; Cell Nucleus; Cerebellum; Chromosomes; Cytoplasm; Cytosine; Dexamethasone; DNA; Dogs; Female; Genetic Code; Guanine; Male; Medulla Oblongata; Rats; RNA; Telencephalon; Thymine | 1973 |
Patterns of purine synthesis related to iridophore development in the wild type, melanoid, and axanthic strains of the Mexican axolotl, Ambystoma mexicanum Shaw.
Topics: Adenine; Ambystoma; Animals; Chromatography, Paper; Chromatophores; Culture Techniques; Genotype; Guanine; Hypoxanthines; Iris; Mutation; Phenotype; Pigmentation; Purines; Xanthines | 1974 |
[Isoenzymes of purine phosphoribosyltransferases in erythrocytes of Lesch-Nyhan patients (author's transl)].
Topics: Adenine; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Erythrocytes; Guanine; Humans; Hypoxanthines; Isoenzymes; Lesch-Nyhan Syndrome; Pentosyltransferases; Purines | 1974 |
[Mutation effect of x-rays. I. Mutagenesis and consequences].
Topics: Adenine; Chromosome Aberrations; Chromosomes; Cytosine; DNA; Female; Fertilization; Guanine; Humans; Mutation; Ovum; Radiation Genetics; Thymine | 1974 |
A combinatorial study of the effects of admitting non-Watson-Crick base pairings and of base composition on the helix-forming potential of polynucleotides of random sequence.
Topics: Adenine; Base Sequence; Cytosine; Genes, Regulator; Guanine; Nucleic Acid Conformation; Polynucleotides; Probability; RNA, Transfer; Uracil | 1974 |
Production of flavine-adenine dinucleotide from riboflavine by a mutant of Sarcina lutea.
Topics: Acetates; Adenine; Adenosine; Air; Aminohydrolases; Culture Media; Cycloserine; Fermentation; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Guanine; Hydrogen-Ion Concentration; Mutation; Penicillins; Riboflavin; Sarcina; Sodium; Streptomycin; Surface-Active Agents; Thiamine | 1974 |
Group separation of ribonucleotides, ribonucleosides, and purine and pyrimidine bases on polyacrylamide gel columns.
Topics: Acrylamides; Adenine; Chromatography, Gel; Cytosine; Guanine; Hydrogen-Ion Concentration; Methods; Polymers; Purines; Pyrimidines; Ribonucleosides; Ribonucleotides; Spectrophotometry, Ultraviolet; Uracil | 1974 |
Fluorescence of complexes of acridine dye with synthetic polydeoxyribonucleotides: a physical model of frameshift mutation.
Topics: Acridines; Adenine; Binding Sites; Coloring Agents; Cytosine; Deoxyribonucleotides; Ethidium; Guanine; Models, Biological; Mutation; Polynucleotides; Potassium Iodide; Rotation; Spectrometry, Fluorescence; Thiamine | 1974 |
The uptake of glycine-14C into the adenine and guanine of DNA and insoluble RNA of human leucocytes.
Topics: Adenine; Autoanalysis; Carbon Radioisotopes; Chromatography, Paper; DNA; Female; Glycine; Gout; Guanine; Humans; Kidney Failure, Chronic; Leukocytes; Male; RNA; Solubility; Uric Acid | 1974 |
Allopurinol and thiopurinol: effect in vivo on urinary oxypurine excretion and rate of synthesis of their ribonucleotides in different enzymatic deficiencies.
Topics: Adenine; Allopurinol; Erythrocytes; Female; Gout; Guanine; Humans; Hypoxanthines; Lesch-Nyhan Syndrome; Male; Pentosephosphates; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Pyrazoles; Pyrimidines; Sulfhydryl Compounds; Time Factors; Uric Acid; Xanthines | 1974 |
[DNA, rRNA and RNA partition isotherms rapidly labeled in a saline solvent system].
Topics: Adenine; Chemical Phenomena; Chemistry; DNA; Guanine; Molecular Weight; RNA; RNA, Ribosomal; Sodium Chloride; Solvents; Temperature | 1974 |
Studies on the role of stimulated epidermal DNA synthesis in the initiation of skin tumors in mice by N-methyl-N'-nitro-N-nitrosoguanidine.
Topics: Acetone; Adenine; Animals; Autoradiography; Croton Oil; DNA; DNA Replication; Female; Guanine; Methylation; Mice; Neoplasms, Experimental; Nitrosoguanidines; Proteins; RNA; Skin; Skin Neoplasms; Thymidine; Tritium | 1974 |
Urinary excretion of methylated purines following inhalation of dimethyl sulphate.
Topics: Adenine; Aerosols; Animals; Chromatography, Ion Exchange; Chromatography, Paper; Guanine; Male; Methane; Methylation; Mice; Purines; Sulfuric Acids; Tritium | 1974 |
Semiconductographic determination of labelled substances in thin-layer chromatography.
Topics: Adenine; Carbon Radioisotopes; Chromatography, Thin Layer; Computers; Cytosine; Guanine; Isotope Labeling; Methods; Phosphorus Radioisotopes; Radionuclide Imaging; Scintillation Counting; Semiconductors; Sulfur Radioisotopes; Temperature; Tritium; Uracil; Uracil Nucleotides; Uridine | 1974 |
Oxidation of nucleic acid bases by potassium peroxodisulfate in alkaline aqueous solution.
Topics: Adenine; Alkalies; Cytosine; Guanine; Kinetics; Oxidation-Reduction; Peroxides; Potassium; Purines; Purinones; Sulfates; Thymine; Uracil | 1974 |
Mass spectrometric studies of the interaction of platinum complexes with nucleoside analogues.
Topics: Adenine; Binding Sites; Cytosine; Guanine; Ligands; Mass Spectrometry; Methylation; Molecular Conformation; Nucleic Acid Conformation; Platinum; Structure-Activity Relationship; Thymine; Time Factors | 1974 |
Studies on hair roots for carrier detection in hypoxanthine-quanine phosphoribosyl transferase deficiency.
Topics: Adenine; Autoradiography; Carbon Radioisotopes; Cells, Cultured; Chromatography, Paper; Electrophoresis; Female; Fibroblasts; Freezing; Genotype; Guanine; Hair; Heterozygote; Humans; Hypoxanthines; Lesch-Nyhan Syndrome; Male; Pedigree; Pentosyltransferases; Sex Chromosomes; Tritium | 1974 |
Chinese hamster cells exhibiting a temperature dependent alteration in purine transport.
Topics: Adenine; Adenosine; Animals; Antimetabolites; Azaguanine; Biological Transport; Carbon Radioisotopes; Cell Division; Cell Line; Cricetinae; Female; Guanine; Guanosine; Hybrid Cells; Hypoxanthines; Inosine Nucleotides; Kinetics; Ovary; Pentosephosphates; Pentosyltransferases; Phenotype; Purines; Temperature; Thymidine | 1974 |
Methylation properties of mitochondrion-specific transfer RNA from cultured hamster cells.
Topics: Adenine; Adenine Nucleotides; Animals; Biological Evolution; Carbon Radioisotopes; Cell Line; Chromatography, Paper; Cricetinae; Cytosine; Electrophoresis, Paper; Electrophoresis, Polyacrylamide Gel; Ethidium; Guanine; Kidney; Methionine; Methylation; Mitochondria; Phosphorus Radioisotopes; Ribose; RNA, Transfer; Species Specificity | 1974 |
Alteration of repression in purine biosynthesis.
Topics: Adenine; Culture Media; Enzyme Repression; Guanine; Hypoxanthines; Molecular Biology; Mutation; Oxidoreductases; Purines; Salmonella typhimurium; Xanthines | 1967 |
Base composition of rapidly-labelled RNA in E. coli undergoing thymineless death.
Topics: Adenine; Chromatography, Ion Exchange; Culture Media; Cytosine; Escherichia coli; Guanine; Molecular Biology; Mutation; RNA, Bacterial; Thymine; Uracil | 1967 |
Partial homology between RNA from rauscher mouse leukemia virus and cellular DNA.
Topics: Adenine; Animals; Chickens; Cytosine; DNA; DNA, Bacterial; Escherichia coli; Guanine; Mice; Rauscher Virus; Ribonucleases; RNA, Viral; Ultracentrifugation; Uracil | 1967 |
On the presence of minor bases in DNA of phages DD7 and Sd and their hosts.
Topics: Adenine; Amines; Coliphages; Cytosine; DNA, Bacterial; DNA, Viral; Escherichia coli; Guanine; Methylation; Purines; Spectrum Analysis; Thymine | 1968 |
Altered base ratios in the DNA of an Escherichia coli mutator strain.
Topics: Adenine; Arginine; Cellulose; Chromatography, Ion Exchange; Cytosine; Densitometry; DNA, Bacterial; Escherichia coli; Genes; Genetic Code; Genetics, Microbial; Glutamates; Guanine; Mutation; Nucleotides; Thymine; Tryptophan; Ultracentrifugation | 1967 |
Defective guanine uptake in an 8-azaguanine-resistant mutant of Salmonella typhimurium.
Topics: Adenine; Azaguanine; Biological Transport; Carbon Isotopes; Drug Resistance, Microbial; Genetics, Microbial; Guanine; Molecular Biology; Mutation; Salmonella typhimurium; Xanthines | 1968 |
In vitro translation of multistranded RNA from Escherichia coli infected by bacteriophage f-2.
Topics: Adenine; Carbon Isotopes; Chromatography, Gel; Coliphages; Electrophoresis; Escherichia coli; Genetic Code; Guanine; RNA, Bacterial; RNA, Messenger; RNA, Viral; Viral Proteins | 1968 |
[Dependent mutation against streptomycin induced by ethyl methanesulfonate in Escherichia coli].
Topics: Adenine; Alkylation; Animals; Chromatography; Culture Media; Cytosine; DNA, Bacterial; Escherichia coli; Genetics, Microbial; Guanine; Molecular Biology; Mutation; Nucleic Acid Denaturation; Ribosomes; Spectrophotometry; Streptomycin; Sulfonic Acids; Tritium; Ultracentrifugation | 1968 |
Mutant of Bacterium paracoli 5099 with an altered DNA: identification as a Flavobacterium.
Topics: Adenine; Centrifugation, Density Gradient; Cytosine; DNA, Bacterial; Enterobacteriaceae; Escherichia coli; Flavobacterium; Genetics, Microbial; Guanine; Molecular Biology; Mutation; Thymine | 1968 |
[On the mechanism of action of D- and L-penicillamine].
Topics: Adenine; Animals; Cell-Free System; Escherichia coli; Guanine; Histocytochemistry; Kidney; Liver; Male; Penicillamine; Peptide Biosynthesis; Rats; Uracil | 1966 |
How different are the DNAs from related animals?
Topics: Adenine; Animals; Biological Evolution; Centrifugation, Density Gradient; Chemical Phenomena; Chemistry; Cricetinae; Cytosine; Densitometry; DNA; DNA, Bacterial; Escherichia coli; Genetic Code; Genetics, Microbial; Guanine; Mice; Nucleic Acid Denaturation; Rats; Species Specificity; Thymine | 1968 |
The influence of 6-mercaptopurine on rat placenta and fetus.
Topics: Abnormalities, Drug-Induced; Adenine; Animals; Chromatography; DNA; Female; Fetus; Glycine; Guanine; Mercaptopurine; Placenta; Pregnancy; Pregnancy, Animal; Rats; RNA; Spinal Dysraphism; Spine | 1968 |
Conformation of ribosomal RNA of E. coli: an infrared analysis.
Topics: Adenine; Cytosine; Escherichia coli; Guanine; Infrared Rays; Methods; Optical Rotatory Dispersion; Polynucleotides; Ribosomes; RNA, Bacterial; Spectrophotometry; Spectrum Analysis; Uracil | 1969 |
Effect of amino acids and purine bases on thiamine synthesis by Escherichia coli.
Topics: Adenine; Amino Acids; Aspartic Acid; Culture Media; Cystine; Cytosine; Escherichia coli; Glutamates; Glycine; Guanine; Histidine; Hypoxanthines; Inositol; Isoleucine; Leucine; Methionine; Phenylalanine; Proline; Purines; Serine; Thiamine; Thiazoles; Threonine; Thymine; Tyrosine; Uracil; Valine | 1968 |
Spectrophotometric investigation of DNA in the ultraviolet. II.
Topics: Adenine; Chemical Phenomena; Chemistry; Cytosine; DNA; DNA, Bacterial; Escherichia coli; Guanine; Hydrogen-Ion Concentration; Nucleic Acid Denaturation; Nucleosides; Nucleotides; Purines; Pyrimidines; Spectrophotometry; Temperature; Thymidine; Thymine; Thymus Gland; Ultraviolet Rays | 1969 |
The degradation of DNA by hydrazine: a critical study of the suitability of the reaction for the quantitative determination of purine nucleotide sequences.
Topics: Adenine; Adenine Nucleotides; Aldehydes; Animals; Carbon Isotopes; Cattle; Chemical Phenomena; Chemistry; Chromatography, Paper; Cytosine Nucleotides; DNA; DNA, Bacterial; Escherichia coli; Guanine; Hydrazines; Nucleotides; Pentoses; Phosphates; Purines; Temperature; Thymus Gland; Time Factors | 1969 |
Studies on ribosomal RNA structure. I. The isolation of crystallizable fragments.
Topics: Adenine; Animals; Cattle; Chromatography, Gel; Crystallization; Escherichia coli; Guanine; Molecular Weight; Pancreas; Rabbits; Reticulocytes; Ribonucleases; Ribosomes; RNA; Saccharomyces; Sodium Hydroxide; Ultracentrifugation; X-Ray Diffraction | 1969 |
Demonstration of sequence differences in the ribonucleic acids of bacteriophage MS2, and a mutant of MS2.
Topics: Adenine; Chromatography, Ion Exchange; Coliphages; Escherichia coli; Genetics, Microbial; Guanine; Hydrogen-Ion Concentration; Methods; Mutation; Nitrites; Nucleotides; Ribonucleases; RNA, Viral; Temperature; Virus Cultivation | 1969 |
Studies on microbial RNA. Fractionation of tRNA methylases from Saccharomyces cerevisiae.
Topics: Adenine; Carbon Isotopes; Chemical Precipitation; Chromatography, Thin Layer; Cytosine; Escherichia coli; Guanine; Magnesium; Manganese; Methionine; Methylation; Nucleosides; Nucleotides; Ribose; RNA, Bacterial; RNA, Transfer; Saccharomyces; Thymine; Transferases | 1969 |
The binding of small cations to deoxyribonucleic acid. Nucleotide specificity.
Topics: Adenine; Amino Acids; Arginine; Calcium; Cesium; Chemical Phenomena; Chemistry; Cytosine; Dialysis; DNA, Bacterial; Escherichia coli; Guanine; Lithium; Lysine; Mathematics; Methods; Micrococcus; Nucleotides; Potassium; Proteus; Quaternary Ammonium Compounds; Serratia marcescens; Sodium; Spermine; Thymine | 1969 |
5S RNA. An analysis of possible base pairing schemes.
Topics: Adenine; Carcinoma; Cell Line; Chemical Phenomena; Chemistry; Computers; Cytosine; Escherichia coli; Guanine; Humans; Models, Chemical; Models, Structural; Mouth Neoplasms; Nucleotides; RNA, Bacterial; RNA, Neoplasm; Uracil | 1969 |
Specificity and efficiency of thymidine incorporation in Escherichia coli lacking thymidine phosphorylase.
Topics: Adenine; Carbon Isotopes; Cytosine; DNA, Bacterial; Escherichia coli; Guanine; Mutation; RNA, Bacterial; Thymidine; Thymine; Transferases; Tritium; Uridine | 1969 |
Genetic regulation of ribonucleoside and deoxyribonucleoside catabolism in Salmonella typhimurium.
Topics: Adenine; Aldehyde-Lyases; Culture Media; Enzyme Induction; Genes; Genetic Code; Genetics, Microbial; Guanine; Mutation; Nucleosides; Pentoses; Phosphotransferases; Ribose; Salmonella typhimurium; Transduction, Genetic; Transferases | 1970 |
[Preface to a grammar of biology. 100 years of nucleic acid research].
Topics: Adenine; Cytosine; DNA; Genetic Code; Guanine; History, 19th Century; History, 20th Century; Molecular Biology; RNA; Thymine | 1970 |
Differential inhibition of bacterial tRNA methylases by S-adenosylethionine and other adenine derivatives.
Topics: Adenine; Carbon Isotopes; Chromatography, Ion Exchange; Cytosine; Escherichia coli; Guanine; Methionine; Methylation; RNA, Bacterial; RNA, Transfer; Transferases; Uracil | 1970 |
The specificity of transfer ribonucleic acid methylases from rat liver.
Topics: Adenine; Animals; Autoradiography; Carbon Isotopes; Chromatography, DEAE-Cellulose; Escherichia coli; Guanine; Kinetics; Liver; Methionine; Methylation; Mutation; Nucleosides; Nucleotides; Pancreas; Rats; Ribonucleases; RNA, Transfer; Transferases; Ultracentrifugation | 1968 |
Ultraviolet light-induced purine modified DNA.
Topics: 1-Propanol; Adenine; Carbon Isotopes; Chromatography, Paper; DNA, Bacterial; Escherichia coli; Guanine; Photochemistry; Purines; Radiation Effects; Ultraviolet Rays | 1970 |
Ribonucleic acids from the mitochondria of bleached Euglena gracilis Z. II. Characterization of highly polymeric ribonucleic acids.
Topics: Adenine; Centrifugation, Density Gradient; Chromatography, Paper; Cytoplasm; Cytosine; Escherichia coli; Euglena; Guanine; Hot Temperature; Magnesium; Mitochondria; Nucleic Acid Denaturation; Nucleotides; Polymers; Ribonucleases; Ribosomes; RNA; Sodium Chloride; Spectrophotometry; Tritium; Uracil | 1970 |
Metabolism of exogenous purine bases and nucleosides by Salmonella typhimurium.
Topics: Adenine; Aminohydrolases; Carbon Isotopes; Culture Media; Guanine; Histidine; Hypoxanthines; Mutation; N-Glycosyl Hydrolases; Nucleosides; Nucleotides; Phosphates; Phosphorus Isotopes; Phosphotransferases; Purines; Salmonella typhimurium; Spectrophotometry; Transduction, Genetic; Transferases | 1971 |
Low-level reading of the UGA triplet in Salmonella typhimurium.
Topics: Adenine; Agar; Genetic Code; Genetics, Microbial; Guanine; Histidine; Lactose; Mutation; Salmonella typhimurium; Suppression, Genetic; Uracil | 1971 |
Electron energy loss spectra of the nucleic acid bases.
Topics: Adenine; Cytosine; Electrons; Energy Transfer; Guanine; Microscopy, Electron, Scanning; Spectrum Analysis; Thymine; Uracil | 1971 |
The effects of diamines and polyamines on enzymic methylation of nucleic acid.
Topics: Acridines; Adenine; Amines; Animals; Biphenyl Compounds; Carbon Isotopes; Chromatography, Paper; Cytosine; Depression, Chemical; Dialysis; Escherichia coli; Guanine; Kidney; Liver; Magnesium; Male; Metabolism; Methionine; Methyltransferases; Osmolar Concentration; Phenanthridines; Polyamines; Rats; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine; Spermine; Spleen; Stimulation, Chemical; Streptomycin; Thymine; Transferases | 1971 |
Auxotroph accumulation in deoxyribonucleic acid polymeraseless strains of Escherichia coli K-12.
Topics: Adenine; Amino Acids; Bacteriological Techniques; Culture Media; DNA Nucleotidyltransferases; Escherichia coli; Genetics, Microbial; Guanine; Mutation; Pantothenic Acid; Uracil | 1971 |
Mutants of T2gt with altered DNA methylase activity: relation to restriction by prophage P1.
Topics: Adenine; Bacteriophages; Carbon Isotopes; Cell-Free System; Chromosome Mapping; Coliphages; Crosses, Genetic; DNA; DNA, Bacterial; DNA, Viral; Escherichia coli; Filtration; Genetics, Microbial; Glucosyltransferases; Guanine; Methylation; Methyltransferases; Micrococcus; Mutation; Recombination, Genetic; Shigella dysenteriae; Trichloroacetic Acid; Tritium | 1971 |
Amino acid sequence of T2 phage lysozyme.
Topics: Adenine; Amino Acid Sequence; Amino Acids; Animals; Chromatography, Paper; Coliphages; Cytosine; Electrophoresis, Paper; Escherichia coli; Guanine; Immune Sera; Muramidase; Peptides; Rabbits; Trypsin; Uracil | 1968 |
Electron microscopic evidence for linear insertion of bacteriophage MU-1 in lysogenic bacteria.
Topics: Adenine; Centrifugation, Density Gradient; Cesium; Chlorides; Coliphages; Conjugation, Genetic; Cytosine; Deuterium; DNA, Bacterial; DNA, Viral; Escherichia coli; Guanine; Lysogeny; Microscopy, Electron; Molecular Weight; Mutation; Oxides; Sulfates; Thymidine; Tritium | 1971 |
Specific excision of methylation products from DNA of Escherichia coli treated with N-methyl-N'-nitro-N-nitrosoguanidine.
Topics: Adenine; Carcinogens; Chromatography, Paper; DNA, Bacterial; Drug Resistance, Microbial; Escherichia coli; Genetics, Microbial; Guanidines; Guanine; Methylation; Mutation; Nitro Compounds; Nitroso Compounds; Nitrosoguanidines; Tritium | 1970 |
The incorporation of glucose to Escherichia coli cells in the presence of noncarbohydrate carbon.
Topics: Adenine; Adenosine Triphosphate; Aerobiosis; Amino Acids; Calorimetry; Carbon; Carbon Dioxide; Carbon Isotopes; Culture Media; Escherichia coli; Glucose; Guanine; Hot Temperature; Manometry; Oxidation-Reduction; Oxygen Consumption; Purines; Pyrimidines; Thymine; Uracil; Vitamins | 1971 |
Some properties of purified cucumber mosaic virus (Q strain).
Topics: Adenine; Cytosine; Electrophoresis; Guanine; Hydrogen-Ion Concentration; Immunodiffusion; In Vitro Techniques; Microscopy, Electron; Molecular Weight; Plant Viruses; RNA, Viral; Sodium Chloride; Spectrum Analysis; Ultracentrifugation; Uracil | 1966 |
Simultaneous spectral determination of both base composition and concentration of DNA.
Topics: Adenine; Animals; Bacillus cereus; Bacillus megaterium; Bacillus subtilis; Cattle; Chemical Phenomena; Chemistry; Cytosine; DNA; DNA, Bacterial; Escherichia coli; Guanine; In Vitro Techniques; Sarcina; Spectrum Analysis; Thymine; Thymus Gland | 1966 |
Heterogeneity of the conserved ribosomal ribonucleic acid sequences of Bacillus subtilis.
Topics: Adenine; Bacillus; Bacillus cereus; Bacillus subtilis; Cytosine; DNA, Bacterial; Guanine; Hybridization, Genetic; In Vitro Techniques; RNA, Bacterial; Tritium; Uridine | 1966 |
Studies on the nucleotide arrangement in deoxyribonucleic acids. X. Frequency and composition of pyrimidine isostichs in microbial deoxyribonucleic acids and in the DNA of E. coli phage T3.
Topics: Adenine; Bacillus cereus; Chromatography; Chromatography, Paper; Coliphages; Cytosine Nucleotides; DNA, Bacterial; DNA, Viral; Escherichia coli; Guanine; Phosphorus; Pyrimidines; Rhodopseudomonas; Salmonella typhi; Salmonella typhimurium; Serratia marcescens; Thymine | 1966 |
Adenine plus thymine and guanine plus cytosine enriched fractions of animal DNA's as indicators of polynucleotide homologies.
Topics: Adenine; Animals; Carbon Isotopes; Centrifugation, Density Gradient; Cricetinae; Cytosine; DNA; Embryo, Mammalian; Guanine; Haplorhini; Hominidae; Hot Temperature; In Vitro Techniques; Mice; Nucleic Acid Denaturation; Phosphorus Isotopes; Polynucleotides; Thymine | 1967 |
Correlation of maximal growth temperature and ribosome heat stability.
Topics: Adenine; Bacillus; Bacillus megaterium; Bacillus subtilis; Bacteria; Cytosine; Desulfovibrio; DNA, Bacterial; Escherichia coli; Guanine; Hot Temperature; In Vitro Techniques; Ribosomes; RNA, Bacterial; Spirillum; Uracil; Vibrio | 1967 |
Unrelatedness of Bacillus amyloliquefaciens and Bacillus subtilis.
Topics: Adenine; Amylases; Bacillus; Bacillus subtilis; Culture Media; Cytosine; DNA, Bacterial; Fermentation; Guanine; Hybridization, Genetic; Lactates; Lactose; Mutation; Thymine; Transduction, Genetic; Transformation, Genetic | 1967 |
Use of exogenous adenine to label the nucleic acids of wild-type Neisseria meningitidis.
Topics: Adenine; Carbon Isotopes; Cytosine; DNA, Bacterial; Guanine; Neisseria meningitidis; Nucleosides; Ribose; RNA, Bacterial; Thymine; Tritium; Uracil | 1967 |
Chemical analysis of DNA alterations. I. Base liberation and backbone breakage of DNA and oligodeoxyadenylic acid induced by hydrogen peroxide and hydroxylamine.
Topics: Adenine; Bacillus subtilis; Carbon Isotopes; Chromatography, Paper; Cytosine; DNA, Bacterial; Guanine; Hydrogen Peroxide; Hydroxylamines; Oxidation-Reduction; Oxides; Oxygen; Pentosephosphates; Polynucleotides; Ribose; Spectrum Analysis; Temperature; Thymine; Ultraviolet Rays | 1968 |
Chemical analysis of DNA alterations. II. Alteration and liberation of bases of deoxynucleotides and deoxynucleosides induced by hydrogen peroxide and hydroxylamine.
Topics: Adenine; Bacillus subtilis; Carbon Isotopes; Chromatography, Paper; Cytosine; DNA, Bacterial; Glycosides; Guanine; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxylamines; Kinetics; Nucleosides; Nucleotides; Pentosephosphates; Phosphates; Spectrum Analysis; Thymine; Ultraviolet Rays | 1968 |
Template functions in the enzymic formation of polyribonucleotides. IV. Denatured DNA as template.
Topics: Adenine; Bacillus subtilis; Cytosine; Dialysis; DNA; DNA, Bacterial; Escherichia coli; Guanine; Hot Temperature; Nucleic Acid Denaturation; Polynucleotides; RNA Nucleotidyltransferases; Templates, Genetic; Thymine; Thymus Gland | 1967 |
Dependence of diaminopurine utilization on the mutational site of purine auxotrophy in Bacillus subtilis. 1. Nutritional experiments.
Topics: Adenine; Bacillus subtilis; Guanine; Hypoxanthines; Mutation; Purines; Xanthines | 1968 |
Dependence of diaminopurine utilization on the mutational site of purine auxotrophy in Bacillus subtilis. II. Tracer experiments.
Topics: Adenine; Adenine Nucleotides; Bacillus subtilis; Carbon Isotopes; Cell-Free System; Guanine; Mutation; Nucleotides; Purines; RNA, Bacterial | 1968 |
The purification and properties of chornic bee-paralysis virus.
Topics: Adenine; Animals; Bees; Centrifugation, Density Gradient; Chemical Precipitation; Cytosine; Guanine; Immunodiffusion; Insect Viruses; Microscopy, Electron; RNA, Viral; Uracil | 1968 |
Chemical analysis of DNA alterations. 3. Isolation and characterization of adenine oxidation products obtained from oligo- and monodeoxyadenylic acids treated with hydroxyl radicals.
Topics: Adenine; Adenine Nucleotides; Bacillus subtilis; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Paper; Coliphages; DNA; Guanine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Mutagens; Mutation; Oxides; Peroxides; Spectrophotometry; Spectrum Analysis; Ultraviolet Rays | 1968 |
Non-random variability in evolution of base compositions of ribosomal RNA.
Topics: Adenine; Amphibians; Animals; Bacillus; Bacillus subtilis; Biological Evolution; Birds; Chlamydia; Cytosine; Drosophila; Echinodermata; Enterobacter; Escherichia coli; Fungi; Guanine; Humans; Mammals; Mitochondria; Plants, Edible; Pseudomonas; Ribosomes; RNA; Species Specificity; Uracil; Zea mays | 1969 |
On the catabolism of deoxyribonucleosides in cells and cell extracts of Escherichia coli.
Topics: Adenine; Aldehyde-Lyases; Bacteriolysis; Carbon Isotopes; Cell Membrane; Cell-Free System; Edetic Acid; Enzyme Induction; Escherichia coli; Guanine; Hypoxanthines; Nucleosides; Osmosis; Pentoses; Purines; Thymidine; Thymine; Toluene; Transferases; Vibration | 1968 |
The metabolism of bacterial nucleic acid and of free components of nucleic acid by the rumen ciliate Entodinium caudatum.
Topics: Adenine; Animals; Carbon Isotopes; Ciliophora; Escherichia coli; Guanine; Nucleic Acids; Phosphorus Isotopes; Purines; Pyrimidines; Thymine; Uracil | 1968 |
Properties of a Pseudomonas aeruginosa bacteriophage phi-MC.
Topics: Adenine; Adsorption; Bacteriophages; Culture Media; Cytosine; DNA, Viral; Glucose; Guanine; Hot Temperature; Mitomycins; Nucleic Acid Denaturation; Pseudomonas aeruginosa; Thymine; Tritium | 1969 |
[Variations of chemical displacement of protons and formation purine-pyrimidine complementary pairs in non aqueous solution].
Topics: Adenine; Chemical Phenomena; Chemistry; Cytosine; Guanine; Magnetic Resonance Spectroscopy; Protons; Quantum Theory; Uracil | 1970 |
Inhibition of methotrexate resistant mutant of Streptococcus faecalis by analogs of purine and pyrimidine.
Topics: Adenine; Adenine Nucleotides; Azaguanine; Drug Resistance, Microbial; Enterococcus faecalis; Guanine; Kinetics; Mercaptopurine; Methotrexate; Mutation; Nucleosides; Purines; Pyrimidines; Thioguanine; Thymine | 1970 |
Template properties of complementary fractions of denatured microbial deoxyribonucleic acids.
Topics: Adenine; Bacillus; Bacillus megaterium; Bacillus subtilis; Coliphages; Cytosine; DNA, Bacterial; DNA, Viral; Escherichia coli; Genetic Code; Guanine; Nucleic Acid Denaturation; Nucleotides; Proteus; Salmonella typhimurium; Serratia marcescens; Templates, Genetic; Uracil | 1970 |
Radio-sensitization with iodine compounds. I. Examination of damage in deoxyribonucleic acid with Bacillus subtilis transformation system by irradiation in the presence of potassium iodide.
Topics: Adenine; Bacillus subtilis; Cobalt Isotopes; Cytosine; DNA Replication; DNA, Bacterial; Guanine; Hydrogen-Ion Concentration; Iodine; Iodoacetates; Potassium Iodide; Radiation Effects; Radiation-Sensitizing Agents; Thymine | 1970 |
[A gasless variant of S. paratyphi B and its epidemiologic significance].
Topics: Adenine; Cytosine; DNA, Bacterial; Guanine; Humans; Paratyphoid Fever; Salmonella paratyphi A; Thymine; Ukraine | 1970 |
Evidence against the folate-mediated formylation of formyl-accepting methionyl transfer ribonucleic acid in Streptococcus faecalis R.
Topics: Adenine; Aminopterin; Bacterial Proteins; Culture Media; Enterococcus faecalis; Folic Acid; Folic Acid Antagonists; Formates; Guanine; Methionine; Pyrimidines; RNA, Transfer; Serine; Thymine | 1970 |
Heterogeneity in nucleotide composition of Bacillus subtilis DNA.
Topics: Adenine; Bacillus subtilis; Centrifugation, Density Gradient; Cytosine; DNA, Bacterial; Guanine; Molecular Weight; Nucleotides; Phosphorus Isotopes; Thymine | 1971 |
[Fluorescence of purine and pyrimidine bases at room temperature].
Topics: Adenine; Cytosine; Fluorescence; Guanine; Hydrogen-Ion Concentration; Purines; Pyrimidines; Spectrum Analysis; Temperature; Thymine; Uracil | 1971 |
[Comparative study of the nucleic acids of 2 species of Spirulina: Spirulina platensis Geitler and Spirulina maxima Geitler].
Topics: Adenine; Chromatography; Cyanobacteria; Cytosine; DNA; Guanine; Purines; Pyrimidines; RNA; Spectrum Analysis; Uracil | 1971 |
Photodynamic mutagenic activity of riboflavin for transforming deoxyribonucleic acid and accelerative effect of adenine.
Topics: Adenine; Bacillus subtilis; DNA; DNA, Bacterial; Guanine; Mutagens; Mutation; Photochemistry; Radiation Genetics; Riboflavin | 1971 |
Thermal denaturation in acidic solutions of double-helical ribonucleic acid from virus-like particles found in Penicillium chrysogenum. A spectrophotometric study.
Topics: Acids; Adenine; Cytosine; Escherichia coli; Guanine; Hot Temperature; Hydrogen-Ion Concentration; Nucleic Acid Denaturation; Penicillium; Penicillium chrysogenum; Plant Viruses; RNA, Bacterial; RNA, Ribosomal; RNA, Viral; Spectrophotometry; Uridine | 1971 |
Inhibition of L-alanine-induced germination of Bacillus cereus spores by theophylline.
Topics: Adenine; Alanine; Bacillus cereus; Caffeine; Drug Synergism; Guanine; Hydrogen-Ion Concentration; Inosine; Spores, Bacterial; Temperature; Theophylline | 1971 |
The isolation and DNA-RNA hybridization of messenger RNA for globin.
Topics: Adenine; Animals; Centrifugation, Density Gradient; Centrifugation, Zonal; Cytosine; Edetic Acid; Electrophoresis, Disc; Genetic Code; Globins; Guanine; Methylation; Mice; Molecular Weight; Nucleic Acid Hybridization; Nucleoproteins; Rabbits; Reticulocytes; RNA, Messenger; RNA, Ribosomal; Sucrose; Time Factors; Uracil | 1971 |
Probable methylation of nucleic acids of mouse colon by 1,2-dimethylhydrazine in vivo.
Topics: Adenine; Alkylating Agents; Animals; Carbon Isotopes; Carcinogens; Chromatography, Ion Exchange; Colon; DNA; Female; Fossil Fuels; Guanine; Hydrazines; Liver; Methylation; Mice; Mice, Inbred Strains; Nucleic Acids; RNA | 1972 |
Populations of repeated DNA sequences in the human genome.
Topics: Adenine; Base Sequence; Centrifugation, Density Gradient; Chromatography; Chromosome Mapping; Chromosomes; Cytosine; DNA; DNA Replication; Guanine; Heterochromatin; Humans; Nucleic Acid Hybridization; Nucleotides; RNA; Temperature; Thymine; Tritium | 1972 |
Interactions between nucleic acid bases.
Topics: Adenine; Computers; Cytosine; Energy Transfer; Guanine; Mathematics; Nucleic Acids; Thymine | 1972 |
Azaguanine-resistance as a manifestation of a new form of metabolic overproduction of uric acid.
Topics: Adenine; Adolescent; Aminopterin; Azaguanine; Blood Urea Nitrogen; Carbon Isotopes; Cell Line; Creatinine; Drug Resistance; Electrophoresis, Starch Gel; Erythrocytes; Fibroblasts; Gout; Guanine; Humans; Hypoxanthines; Lesch-Nyhan Syndrome; Male; Mercaptopurine; Pentosyltransferases; Purines; Uric Acid | 1972 |
Origin of the small component of brome mosaic virus RNA.
Topics: Adenine; Base Sequence; Chromatography, DEAE-Cellulose; Electrophoresis, Disc; Guanine; Phosphorus Isotopes; Plant Viruses; Ribonucleases; RNA, Viral | 1972 |
The level of a relatively purine-specific ribonuclease increases in virus-infected hypersensitive or mechanically injured tobacco leaves.
Topics: Acid Phosphatase; Adenine; Alkaline Phosphatase; Ammonium Sulfate; Chemical Precipitation; Chromatography, DEAE-Cellulose; Chromatography, Gel; Deoxyribonucleases; Electrophoresis, Disc; Guanine; Nicotiana; Plant Diseases; Plant Extracts; Plants, Toxic; Purines; Ribonucleases; Time Factors; Tobacco Mosaic Virus; Virus Replication | 1972 |
Purine metabolism in wheat shoots treated with aminotriazole.
Topics: Adenine; Adenine Nucleotides; Amines; Carbon Isotopes; Chromatography, Ion Exchange; Chromatography, Paper; Glycine; Guanine; Histidine; Light; Plants; Polynucleotides; Purines; Radiation Effects; Triazoles | 1972 |
Adaptive significance of inosine and adenosine kinase activities in cultured human skin fibroblasts.
Topics: Adenine; Adenosine; Azaserine; Cells, Cultured; Fibroblasts; Guanine; Humans; Hypoxanthines; Inosine; Lesch-Nyhan Syndrome; Phosphotransferases; Skin; Thymidine; Tritium | 1972 |
A method for calculating codon frequencies in DNA.
Topics: Adenine; Amino Acid Sequence; Base Sequence; Cytosine; DNA; Genetic Code; Guanine; Mathematics; Models, Biological; Purines; Pyrimidines; Thymine | 1972 |
Isoenzymes of hypoxanthine-guanine-phosphoribosyl transferase in a family with partial deficiency of the enzyme.
Topics: Adenine; Blood Protein Electrophoresis; Carbon Isotopes; Electrophoresis, Disc; Erythrocytes; Female; Genetic Linkage; Guanine; Heterozygote; Hot Temperature; Humans; Hypoxanthines; Isoenzymes; Kinetics; Lesch-Nyhan Syndrome; Male; Metabolism, Inborn Errors; Methods; Pentosyltransferases; Sex Chromosomes; Time Factors | 1972 |
[Radiation-chemical synthesis of deoxynucleosides].
Topics: Adenine; Guanine; Nucleosides; Radiochemistry | 1972 |
Effect of adenine and guanine on glucose uptake of the heart.
Topics: Adenine; Animals; Glucose; Guanine; Heart; In Vitro Techniques; Insulin; Myocardium; Perfusion; Rats; Stimulation, Chemical | 1972 |
Mitoribosomes from Candida utilis. Morphological, physical, and chemical characterization of the monomer form and of its subunits.
Topics: Adenine; Candida; Carbon Isotopes; Centrifugation, Density Gradient; Chloramphenicol; Cytosine; Depression, Chemical; Guanine; Leucine; Microscopy, Electron; Mitochondria; Models, Structural; Phosphorus Isotopes; Protein Biosynthesis; Puromycin; Ribosomes; RNA, Ribosomal; Uracil | 1972 |
Studies on the mechanism of fructose-induced hyperuricemia in man.
Topics: Adenine; Adenosine Triphosphate; Aged; Allopurinol; Erythrocytes; Fasting; Fructose; Glucose; Gout; Guanine; Humans; Hypoxanthines; Lactates; Male; Metabolic Clearance Rate; Middle Aged; Pentosyltransferases; Phosphates; Purine Nucleotides; Purines; Ribose; Uric Acid | 1972 |
Reaction of nitrous acid with viral nucleic acids in stitu.
Topics: Absorption; Adenine; Centrifugation, Density Gradient; Cytosine Nucleotides; Deamination; Guanine; Hypoxanthines; Nicotiana; Nitrites; Plant Viruses; Plants, Edible; Plants, Toxic; RNA, Viral; Species Specificity; Spectrophotometry; Time Factors; Tobacco Mosaic Virus; Ultraviolet Rays; Uracil Nucleotides; Viral Proteins; Virus Cultivation; Xanthines | 1972 |
Deoxyribonucleic acid relationships among marine vibrios.
Topics: Adenine; Chemical Precipitation; Culture Media; Cytosine; DNA, Bacterial; Guanine; Hot Temperature; Nucleic Acid Denaturation; Nucleic Acid Hybridization; Seawater; Serotyping; Trichloroacetic Acid; Tritium; Vibrio; Water Microbiology | 1972 |
Replicative heterogeneity of mammalian DNA.
Topics: Adenine; Animals; Autoradiography; Carbon Isotopes; Cell Count; Cell Line; Centrifugation, Density Gradient; Cricetinae; Cytosine; DNA; DNA Replication; Guanine; Heterochromatin; Lung; Methods; Mitosis; Thymidine; Thymine; Time Factors; Tritium | 1972 |
Further studies of the enzyme composition of mutant cells in X-linked uric aciduria.
Topics: Adenine; Athetosis; Erythrocytes; Fibroblasts; Guanine; Humans; Hypoxanthines; Inosine; Intellectual Disability; Lesch-Nyhan Syndrome; Phosphotransferases; Purine-Pyrimidine Metabolism, Inborn Errors; Self Mutilation; Sex Chromosomes | 1972 |
Optimised parameters for RNA double-helices.
Topics: Adenine; Cytosine; Guanine; Models, Structural; Nucleic Acid Conformation; Phosphates; Poly A-U; Poly I-C; Polynucleotides; Ribose; RNA; Stereoisomerism; Uracil; X-Ray Diffraction | 1972 |
Anomeric configuration of nucleosides by application of the internal Nuclear Overhauser Effect.
Topics: Adenine; Chemical Phenomena; Chemistry; Deoxyribonucleosides; Fluorouracil; Furans; Guanine; Hypoxanthines; Magnetic Resonance Spectroscopy; Mathematics; Molecular Conformation; Nucleic Acid Conformation; Nucleosides; Spectrum Analysis; Stereoisomerism; Uracil | 1972 |
Factor-independent interaction of met-tRNA i and ApUpG with 40 S subunits of rat liver ribosomes.
Topics: Adenine; Animals; Anti-Bacterial Agents; Benzoates; Cyclohexanecarboxylic Acids; Genetic Code; Guanine; Liver; Magnesium; Methionine; Peptide Chain Initiation, Translational; Peptide Initiation Factors; Peptides; Phenols; Polynucleotides; Rats; Ribosomes; RNA, Transfer; Transfer RNA Aminoacylation; Tritium; Uridine | 1972 |
A molecular orbital study on the alkylation and depurination reactions of the base components of nucleic acids.
Topics: Adenine; Alkylating Agents; Alkylation; Binding Sites; Computers; Cytosine; DNA; Electrons; Guanine; Hydrogen; Models, Chemical; Nucleic Acids; Nucleotides; Protons; Purines; Structure-Activity Relationship | 1972 |
Concerning the mechanism of FSH action: rapid stimulation of testicular synthesis of nuclear RNA.
Topics: Adenine; Animals; Carbon Isotopes; Cell Nucleus; Chromosomes; Cytosine; Electrophoresis, Disc; Follicle Stimulating Hormone; Guanine; In Vitro Techniques; Male; Nucleosides; Peptides; Protein Biosynthesis; Rats; Ribosomes; RNA; Stimulation, Chemical; Templates, Genetic; Testis; Tritium; Uracil; Valine | 1971 |
A study of chemically methylated deoxyribonucleic acid.
Topics: Adenine; Animals; Binding Sites; Cattle; Circular Dichroism; Dialysis; DNA, Bacterial; Filtration; Guanine; Hot Temperature; Luminescent Measurements; Lysine; Methylation; Protein Denaturation; RNA Nucleotidyltransferases; Spermine; Viscosity | 1971 |
Action of the carcinogen 7-bromomethylbenz(a)anthracene on DNA.
Topics: Adenine; Animals; Benz(a)Anthracenes; Binding Sites; Bromine; Chemical Phenomena; Chemistry; DNA; DNA, Bacterial; Fluorescence; Guanine; Micrococcus; Optical Rotatory Dispersion; Ribonucleotides; Salmonidae | 1971 |
Inhibition of guanine metabolism of mammalian tumor cells by the carbocyclic analogue of adenosine.
Topics: Adenine; Adenocarcinoma; Adenosine; Carbon Isotopes; Cells, Cultured; Chromatography, Paper; Cyclopentanes; Guanine; Guanine Nucleotides; Hypoxanthines; Inosine Nucleotides; Kinetics; Neoplasms, Experimental; Pentosephosphates; Pentosyltransferases; Phosphotransferases | 1971 |
Effect of reserpine on sympathetic neuronal RNA.
Topics: Adenine; Animals; Cytosine; Ganglia, Autonomic; Guanine; Lumbosacral Region; Male; Micromanipulation; Neurons; Rats; Reserpine; Ribosomes; RNA; Sympathetic Nervous System; Time Factors; Uracil | 1971 |
Transfer ribonucleic acid methylases during the germination of Neurospora crassa.
Topics: Adenine; Carbon Isotopes; Cell-Free System; Chromatography, Thin Layer; Culture Media; Guanine; Hydrolysis; Methylation; Methyltransferases; Neurospora; Phenols; RNA, Transfer; S-Adenosylmethionine; Spores; Spores, Fungal | 1971 |
The substrate specificity of purine phosphoribosyltransferases in Schizosaccharomyces pombe.
Topics: Adenine; Adenosine Monophosphate; Ascomycota; Carbon Isotopes; Genotype; Guanine; Hydrogen-Ion Concentration; Hypoxanthines; Mutation; Pentosyltransferases; Purines; Temperature; Xanthines | 1971 |
[Several aspects of radiodenaturation of deoxyribonucleic acid (DNA)].
Topics: Adenine; Animals; Cattle; Circular Dichroism; Cytosine; Diffusion; DNA; Guanine; Molecular Weight; Nucleic Acid Denaturation; Nucleotides; Optical Rotatory Dispersion; Radiation Effects; Spectrum Analysis; Thymine; Thymus Gland | 1971 |
Deoxyribonucleic acid replication. A theoretical study of Löwdin's mechanism.
Topics: Adenine; Cytosine; DNA Replication; Electrochemistry; Guanine; Models, Chemical; Thymine | 1971 |
[Protonization of purine, adenine, and guanine. NMR spectra and structure of mono, di, and tri cations].
Topics: Adenine; Guanine; Ions; Magnetic Resonance Spectroscopy; Methylation | 1971 |
Incorporation of precursors into Toxoplasma DNA.
Topics: Adenine; Animals; Carbon Isotopes; Cytidine; DNA; Guanine; Hot Temperature; Mice; Mice, Inbred Strains; Nucleic Acid Denaturation; Nucleotides; Orotic Acid; Purines; Pyrimidines; Thymidine; Time Factors; Toxoplasma; Tritium | 1971 |
[Proton transfer in model systems for complementary base pairing in nucleic acids].
Topics: Adenine; Base Sequence; Cytosine; DNA; Energy Transfer; Guanine; Infrared Rays; Models, Structural; Protons; Spectrum Analysis; Thymine | 1971 |
Turnover of purine nucleotides in rabbit erythrocytes: lack of in vivo effect of the nucleoside transport inhibitor, p-nitrobenzyl-6-thioguanosine.
Topics: Adenine; Animals; Biological Transport; Carbon Isotopes; Chromatography, Paper; Erythrocytes; Guanine; Guanosine; Half-Life; Hypoxanthines; In Vitro Techniques; Inosine; Kinetics; Male; Nitrobenzenes; Nucleosides; Nucleotides; Purine Nucleotides; Rabbits; Thioguanine | 1971 |
The effect of adenine and guanine on the glucose uptake of the heart.
Topics: Adenine; Animals; Glucose; Guanine; Heart; In Vitro Techniques; Insulin; Myocardium; Perfusion; Rats | 1971 |
Nuclear and cytoplasmic RNA in normal and dystrophic neurons.
Topics: Adenine; Animals; Cell Nucleus; Cytoplasm; Cytosine; Guanine; Motor Neurons; Neuromuscular Diseases; Rats; RNA; Uracil; Vestibular Nuclei | 1971 |
The mechanism of aristeromycin. I. Growth inhibition of Xanthomonas oryzae by aristeromycin.
Topics: Adenine; Adenosine; Anti-Bacterial Agents; Cytidine; Cytosine; Deoxyuridine; Guanine; Guanosine; Hypoxanthines; Inosine; Nucleosides; Thymidine; Thymine; Uracil; Uridine; Xanthines; Xanthomonas | 1971 |
The action of mono- and di-functional sulphur mustards on the ribonucleic acid-containing bacteriophage mu2.
Topics: Adenine; Alkylation; Binding Sites; Chromatography; Coliphages; Cytosine; Formaldehyde; Guanine; Mustard Compounds; Nucleosides; Nucleotides; RNA, Viral; Sulfur Isotopes; Ultracentrifugation; Viral Proteins | 1971 |
Interaction of the carcinogen N-acetoxy-N-2-acetylaminofluorene with polyadenylic acid: dependence of reactivity on conformation.
Topics: Acetates; Adenine; Adenine Nucleotides; Adenosine Monophosphate; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography; Chromatography, Thin Layer; Fluorenes; Guanidines; Guanine; Hydrogen-Ion Concentration; Polynucleotides; Structure-Activity Relationship; Tritium; Uracil | 1971 |
Transcriptional mapping of ribosomal RNA genes of the chloroplast and nucleus of Chlamydomonas reinhardi.
Topics: Adenine; Binding Sites; Carbon Isotopes; Cell Nucleus; Chlamydomonas; Chloroplasts; Chromosome Mapping; Dactinomycin; DNA; Electrophoresis, Disc; Genetic Code; Guanine; Mitochondria; Operon; Rifampin; RNA; RNA, Ribosomal | 1971 |
Adenine as substrate for purine nucleoside phosphorylase.
Topics: Adenine; Animals; Brain; Carbon Isotopes; Chick Embryo; Chromatography, Gel; Chromatography, Paper; Erythrocytes; Female; Guanine; Humans; Kinetics; Liver; Mice; Pentosephosphates; Pentosyltransferases; Rats; Ribose; Sarcoma 180; Selenium; Spectrophotometry; Spleen | 1971 |
The nucleotide composition of labelled RNA synthesized by chick-embryo sensory ganglia during outgrowth of fibres in vitro.
Topics: Adenine; Animals; Chick Embryo; Chromatography; Cytosine; Ganglia; Guanine; Nucleotides; RNA, Ribosomal; Uridine | 1971 |
Pathways of purine ribonucleotide catabolism in Ehrlich ascites tumor cells in vitro.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cell Line; Guanine; Guanine Nucleotides; Guanosine; Hypoxanthines; Inosine; Inosine Nucleotides; Kinetics; Models, Biological; Nucleotides; Ribonucleosides; Ribonucleotides; Xanthines | 1971 |
Hydrolysis of adenosine monophosphates by acid phosphatases as measured by a continuous spectrophotometric assay.
Topics: Adenine; Adenine Nucleotides; Adenosine Monophosphate; Alkaline Phosphatase; Animals; Cattle; Enzyme Activation; Erythrocytes; Glycerophosphates; Guanine; Humans; Hydrolysis; Intestines; Kidney; Kinetics; Liver; Male; Plants; Prostate; Rats; Spectrophotometry; Stereoisomerism; Structure-Activity Relationship; Ultraviolet Rays | 1970 |
Analysis of base composition of RNA and DNA hydrolysates by gas-liquid chromatography.
Topics: Adenine; Animals; Base Sequence; Cattle; Charcoal; Chromatography, Gas; Chromatography, Ion Exchange; Cytosine; DNA; Guanine; Hydrogen-Ion Concentration; Hydrolysis; Ion Exchange Resins; Male; Methods; Methylation; Microchemistry; Purines; Pyrimidines; RNA; Salmonidae; Spermatozoa; Thymine; Thymus Gland; Tissue Extracts; Uracil; Yeasts | 1971 |
Precursor pools and RNA synthesis in preimplantation mouse embryos.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Animals; Chromatography, Paper; Embryo Implantation; Embryo, Mammalian; Female; Gestational Age; Guanine; Mice; Mice, Inbred Strains; Purines; Pyrimidines; RNA; Spectrophotometry; Tritium; Uridine | 1971 |
The relationship of Mycoplasma pneumoniae (Eaton agent) to Streptococcus MG: application of genetic tests to determine relatedness of L-forms and PPLO to bacteria.
Topics: Adenine; Chemical Phenomena; Chemistry; Cytosine; DNA, Bacterial; Guanine; In Vitro Techniques; L Forms; Molecular Biology; Mycoplasma; Streptococcus; Thymine | 1965 |
Formal discussion on resistance to purine antagonists in experimental leukemia systems.
Topics: Adenine; Animals; Guanine; Humans; Hypoxanthines; In Vitro Techniques; Leukemia, Lymphoid; Leukemia, Myeloid; Mercaptopurine; Mice; Nucleotidyltransferases | 1965 |
Van der Waals-London interactions and the configuration of hydrogen-bonded purine and pyrimidine pairs.
Topics: Adenine; Chemical Phenomena; Chemistry, Physical; Cytosine; Guanine; Hydrogen; Purines; Pyrimidines; Thymine | 1966 |
Production of antibodies to soluble RNA (sRNA).
Topics: Adenine; Animals; Antibody Formation; Complement Fixation Tests; Cytosine; Guanine; Haptens; Immune Sera; In Vitro Techniques; Kidney; Liver; Lung; Nucleosides; Nucleotides; Rabbits; Ribose; RNA, Transfer; Spleen; Thymus Gland; Uracil; Yeasts | 1965 |
Regional and temporal control of genetic transcription in phage lambda.
Topics: Adenine; Coliphages; Cytosine; Genetic Code; Guanine; Molecular Biology; RNA, Messenger; RNA, Viral; Uracil | 1966 |
A search for an intermediate involving a complement during synchronous synthesis by a purified RNA replicase.
Topics: Adenine; Chemical Phenomena; Chemistry; Coliphages; Cytosine; Guanine; Hot Temperature; Nucleotidyltransferases; Ribonucleases; RNA, Viral; Uracil | 1966 |
Interaction energies in hydrogen-bonded purine-pyrimidine triplets.
Topics: Adenine; Chemical Phenomena; Chemistry, Physical; Cytosine; Energy Transfer; Guanine; Hydrogen; Hypoxanthines; Purines; Pyrimidines; Uracil | 1967 |
Studies on macrophage RNA involved in antibody production.
Topics: Adenine; Animals; Antibody Formation; Centrifugation, Density Gradient; Coliphages; Culture Techniques; Cytosine; Guanine; Macrophages; Rats; RNA; Spleen; Uracil | 1967 |
RNA synthesis in reovirus-infected L929 mouse fibroblasts.
Topics: Adenine; Animals; Culture Techniques; Cytopathogenic Effect, Viral; Cytosine; Dactinomycin; Fibroblasts; Guanine; Mice; Phosphorus Isotopes; Reoviridae; RNA, Viral; Tritium; Uracil; Uridine | 1967 |
Base composition and metabolism of various RNA fractions in Acetabularia mediterranea.
Topics: Adenine; Cell Nucleolus; Cell Nucleus; Centrifugation, Density Gradient; Chloroplasts; Chromatography, Thin Layer; Cytosine; DNA; Electrophoresis; Eukaryota; Guanine; Ribosomes; RNA; RNA, Messenger; Sucrose; Tritium; Uracil; Uridine | 1968 |
Identification of guanosine triphosphate as the 5'-terminus of RNA from bacteriophage Q-beta and R23.
Topics: Adenine; Alkalies; Coliphages; Cytosine; Electrophoresis; Guanine; Guanine Nucleotides; Phosphorus Isotopes; RNA, Viral; Tritium; Uracil | 1968 |
Purine requirement of cells cultured from humans affected with Lesch-Nyhan syndrome (hypoxanthine-guanine phosphoribosyltransferase deficiency).
Topics: Adenine; Clone Cells; Culture Techniques; Female; Folic Acid; Guanine; Humans; Hypoxanthines; Phenotype; Purine-Pyrimidine Metabolism, Inborn Errors; Sex Chromosome Aberrations; Transferases | 1969 |
Alteration of gene conversion patterns in Sordaria fimicola by supplementation with DNA bases.
Topics: Adenine; Ascomycota; Crosses, Genetic; Cytosine; Guanine; Mutation; Thymine | 1970 |
IMP: and AMP:pyrophosphate phosphoribosyltransferase in leukemic and normal human leukocytes.
Topics: Adenine; Carbon Isotopes; Erythrocytes; Guanine; Humans; Hypoxanthines; In Vitro Techniques; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocytes; Transferases | 1971 |
Interaction between loops 1 and 3 in the tyrosine suppressor tRNA.
Topics: Adenine; Base Sequence; Chromatography, DEAE-Cellulose; Cytosine; Guanine; Hydroxylamines; Mutation; Phosphorus Isotopes; Polynucleotides; Ribonucleases; RNA, Transfer; Suppression, Genetic; Tyrosine | 1971 |
In vivo methylation of DNA in human leukocytes.
Topics: Adenine; Cytosine; DNA; Guanine; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocytes; Methionine; Methylation; Thymine; Tritium | 1971 |
Fluorescence of gamma-irradiated DNA and purines in aqueous soltuion.
Topics: Adenine; Chemical Phenomena; Chemistry; Cytosine; Cytosine Nucleotides; DNA; Fluorescence; Guanine; Guanine Nucleotides; Nucleotides; Purines; Radiation Effects; Spectrum Analysis; Thymine | 1968 |
The effect of histones on the enzymatic synthesis of ribonucleic acid.
Topics: Adenine; Animals; Arginine; Cattle; Cytosine; DNA; Escherichia coli; Guanine; Histones; In Vitro Techniques; Lysine; Nucleotidyltransferases; RNA; RNA, Bacterial; Thymine; Thymus Gland | 1966 |
Isolation and base composition of anticodon strand of DNA and its relation to rapidly labeled RNA.
Topics: Adenine; Chemical Phenomena; Chemistry; Cytosine; DNA, Bacterial; Escherichia coli; Genetic Code; Guanine; In Vitro Techniques; RNA, Bacterial; Thymine | 1965 |
The unusual mutagenic specificity of an E. Coli mutator gene.
Topics: Adenine; Cytosine; Escherichia coli; Genes; Genetic Code; Guanine; Hydro-Lyases; In Vitro Techniques; Molecular Biology; Mutation; RNA, Bacterial; Thymine | 1966 |
Inhibition of J-128 (Osgood) cell culture by azaserine.
Topics: Adenine; Azaserine; Culture Techniques; DNA; Guanine; Imidazoles; Microscopy, Phase-Contrast; Nucleosides | 1966 |
The lethality of streptomycin and the stimulation of RNA synthesis in the absence of protein synthesis.
Topics: Adenine; Arginine; Bacterial Proteins; Carbon Isotopes; Chloramphenicol; Drug Resistance, Microbial; Escherichia coli; Fluorouracil; Guanine; Kanamycin; Neomycin; Phosphates; RNA, Bacterial; Streptomycin; Sulfur Isotopes; Thymine; Uracil | 1966 |
Studies on depurination and alkylation of DNA's of different base compositions.
Topics: Adenine; Alkylation; Animals; Cattle; Chromatography, Paper; DNA; DNA, Bacterial; Escherichia coli; Guanine; Hot Temperature; Hydrogen-Ion Concentration; Mutation; Purines; RNA; Sarcina; Thymus Gland | 1966 |
The preferential interactions of polylysine and polyarginine with specific base sequences in DNA.
Topics: Adenine; Arginine; Chemical Phenomena; Chemistry; Cytosine; DNA, Bacterial; Guanine; Lysine; Peptides; Phosphorus Isotopes; Polynucleotides; Proteus; Serratia marcescens; Spectrophotometry; Thymine | 1966 |
Further evidence that UGA does not code for tryptophan.
Topics: Adenine; Escherichia coli; Genetic Code; Guanine; Molecular Biology; Mutation; Nucleotides; Purines; Tryptophan; Uracil | 1967 |
Conversion of adenine to guanine and cytosine to uracil by chick embryo sensory ganglia in tissue culture.
Topics: Adenine; Animals; Chick Embryo; Culture Techniques; Electrophoresis; Ganglia, Autonomic; Guanine; Nerve Growth Factors; Neurons; Nucleosides; RNA; Tritium; Uracil | 1969 |
Ion-exchange chromatography of tissue nucleotides.
Topics: Adenine; Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Chromatography, Ion Exchange; Guanine; Liver; Mercaptopurine; Mice; Nucleosides; Nucleotides; Spectrophotometry; Tissue Extracts | 1969 |
Methylation of rat-liver RNA in vivo by methyl methanesulphonate.
Topics: Adenine; Animals; Carbon Isotopes; Chromatography, Ion Exchange; Chromatography, Paper; Guanine; Hydrogen-Ion Concentration; Liver; Male; Methylation; Nucleotides; Purinones; Rats; RNA; Solubility; Sulfonic Acids; Time Factors | 1969 |
[Purine metabolism and riboflavin formation in microorganisms. II. Purine metabolism and riboflavin synthesis of a purine deficiency mutant of Candida guilliermondii (Cast.) Lang. et G].
Topics: Absorption; Adenine; Candida; Carbon Isotopes; Culture Media; Guanine; Hypoxanthines; Mutation; Nucleosides; Nucleotides; Purines; Riboflavin; Spectrophotometry; Xanthines | 1969 |
[The mechanism of chemical mutagenesis in the light of the mutagenic action of hydroxylamine].
Topics: Adenine; Cytosine; DNA; Guanine; Hydroxylamines; Mutagens; Mutation; Nitrites; Polymers; RNA; Uracil | 1969 |
[Modification of light erythema of human skin by pyrimidine and purine bases (preliminary report)].
Topics: Adenine; Alkalies; Emulsions; Erythema; Guanine; Humans; Purines; Pyrimidines; Sunburn; Sunscreening Agents; Ultraviolet Rays; Uracil; Xanthines | 1969 |
Characterization and relatedness of marine vibrios pathogenic to fish: deoxyribonucleic acid homology and base composition.
Topics: Adenine; Animals; Carbon Isotopes; Cytosine; DNA, Bacterial; Fishes; Guanine; Nucleic Acid Denaturation; Uracil; Vibrio; Vibrio Infections | 1969 |
Purine nucleosides. XXIX. The synthesis of 2'-deoxy-L-adenosine and 2'-deoxy-L-guanosine and their alpha anomers.
Topics: Adenine; Amines; Chemical Phenomena; Chemistry; Guanine; Magnetic Resonance Spectroscopy; Nucleosides; Stereoisomerism | 1970 |
Kinetics and mechanism of the acid-catalyzed hydrolysis of some purine nucleosides.
Topics: Adenine; Catalysis; Chemical Phenomena; Chemistry; Guanine; Hydrogen-Ion Concentration; Kinetics; Nucleosides; Spectrophotometry | 1970 |
Nucleoside antibiotics. VI. Biosynthesis of the pyrrolopyrimidine nucleoside antibiotic toyocamycin by Streptomyces rimosus.
Topics: Adenine; Anti-Bacterial Agents; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Formates; Guanine; Nucleosides; Pyrimidines; Pyrroles; Streptomyces | 1970 |
Studies on beta-D-xylofuranosyl-6-thioguanine in mice.
Topics: Adenine; Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cell Line; Chromatography; DNA, Neoplasm; Female; Furans; Glycine; Guanine; Immunosuppressive Agents; Male; Mice; Neoplasms, Experimental; Orotic Acid; Protein Biosynthesis; Purines; Pyrimidines; RNA, Neoplasm; Sulfur Isotopes; Thioguanine; Xylose | 1970 |
Satellite DNAs in crustacea: 2 different components with the same density in neutral CsCl gradients.
Topics: Adenine; Centrifugation, Density Gradient; Crustacea; Cytosine; DNA; Guanine; Hot Temperature; Nucleic Acid Denaturation; Polynucleotides; Specific Gravity; Thymine | 1970 |
The reaction of phenyl isocyanate with purines, pyrimidines and deoxyribonucleic acid.
Topics: Adenine; Chemical Phenomena; Chemistry; Cyanates; Cytosine; DNA; Guanine; Infrared Rays; Purines; Pyrimidines; Spectrophotometry; Spectrum Analysis | 1970 |
Stereochemistry of nucleic acids and polynucleotides. II. Allowed conformations of the monomer unit for different ribose puckerings.
Topics: Adenine; Chemical Phenomena; Chemistry; Computers; Cytosine; Guanine; Nucleic Acids; Nucleosides; Nucleotides; Polynucleotides; Ribose; Stereoisomerism; Thymine | 1970 |
A comparison of the oncogenicities of 3-hydroxyxanthine, guanine 3-N-oxide, and some related compounds.
Topics: Adenine; Animals; Chemical Phenomena; Chemistry; Female; Granuloma; Guanine; Injections, Subcutaneous; Liver Neoplasms; Male; Mercaptopurine; Neoplasms, Experimental; Oxides; Purines; Rats; Xanthines | 1970 |
Metabolism of an antineoplastic methylhydrazine derivative in a P815 mouse neoplasm.
Topics: Adenine; Animals; Antineoplastic Agents; Benzoates; Carbon Isotopes; Cell Line; Chromatography, Paper; Chromatography, Thin Layer; Cytoplasm; Cytosine; Female; Guanine; Hydrazines; Male; Methionine; Mice; Neoplasms, Experimental; RNA, Neoplasm; Thymine; Tritium | 1970 |
[Enzymopathic gout. Dyspurinia due to hypoxanthine-guanine-phosphoribosyl-transferase deficiency. Occurrence and clinical characteristics of enzyme repression].
Topics: Adenine; Adult; Age Factors; Allopurinol; Enzyme Repression; Female; Gout; Guanine; Humans; Hypoxanthines; Kidney Calculi; Kidney Diseases; Male; Pedigree; Transferases; Uric Acid; Xanthines | 1970 |
[Conversion of histidine into urocaninic acid in the epidermis].
Topics: Acrylates; Adenine; Animals; Autoradiography; Chromatography; Epithelium; Guanine; Histidine; Imidazoles; Mice; Skin; Tritium | 1970 |
[Purine metabolism and riboflavin production in microorganisms. VII. Regulation of purine nucleotide synthesis through adenine in Candida guilliermondii (Cast.) Lang. et G].
Topics: Adenine; Adenine Nucleotides; Candida; Carbon Isotopes; Depression, Chemical; Glycine; Guanine; Imidazoles; Nucleic Acids; Nucleosides; Purines; Riboflavin | 1970 |
Phosphoribosyltransferase activity during early mammalian development.
Topics: Adenine; Animals; Embryo Implantation; Embryo, Mammalian; Female; Guanine; Hypoxanthines; Mice; Morphogenesis; Ovum; Rabbits; Transferases | 1970 |
Antagonism by adenine in the nutrition of Schizosaccharomyces pombe mutants. Inhibition at the level of guanine uptake.
Topics: Adenine; Carbon Isotopes; Guanine; Hypoxanthines; Kinetics; Mutation; Saccharomyces | 1970 |
Satellite DNA sequence.
Topics: Adenine; Animals; Chromosomes; Cytosine; DNA; Guanine; Guinea Pigs; Nucleic Acid Denaturation; Nucleotides; Specific Gravity; Thymine | 1970 |
Diagnosis of Lesch-Nyhan syndrome by direct study of skin specimens.
Topics: Adenine; Adolescent; Adult; Aged; Child; Clinical Enzyme Tests; Erythrocytes; Female; Fibroblasts; Guanine; Heterozygote; Humans; Hypoxanthines; Intellectual Disability; Male; Metabolism, Inborn Errors; Middle Aged; Movement Disorders; Self Mutilation; Skin; Transferases; Tritium; Uric Acid | 1970 |
[Problems of the chemotaxonomy of protozoa].
Topics: Adenine; Animals; Cytosine; DNA; Eukaryota; Guanine; Methods; Molecular Weight; RNA; RNA, Messenger; RNA, Transfer; Thymine; Uracil | 1970 |
Estrogen-mediated enhancement of rat liver sRNA methylase activity.
Topics: Adenine; Administration, Oral; Animals; Carbon Isotopes; Castration; Cell Nucleolus; Dactinomycin; Female; Guanine; Hypophysectomy; Injections, Subcutaneous; Liver; Male; Mestranol; Methylation; Nucleosides; Ovary; Pituitary Gland; RNA, Transfer; Sesame Oil; Stimulation, Chemical; Transferases; Uridine | 1970 |
Purines: supply by liver to tissues.
Topics: Adenine; Animals; Carbon Isotopes; Chromatography; Erythrocytes; Guanine; Hypoxanthines; In Vitro Techniques; Liver; Male; Perfusion; Purines; Rats | 1970 |
[About an atypical catabolism of purines during the epidermal keratinization].
Topics: Adenine; Allantoin; Animals; Carbon Isotopes; Chromatography; Chromatography, Paper; Guanine; Guinea Pigs; Humans; Hypoxanthines; Keratins; Mice; Purines; Skin; Urea; Uric Acid; Xanthines | 1970 |
Analytical study of the degradation of nucleohistone during calf thymus chromatin autolysis.
Topics: Adenine; Amino Acids; Animals; Autolysis; Cattle; Cytosine; DNA; Electrophoresis; Guanine; Histones; Molecular Weight; Nucleoproteins; Thymine; Thymus Gland | 1970 |
A new assay method for hypoxanthine-guanine phosphoribosyltransferase.
Topics: Adenine; Adenine Nucleotides; Athetosis; Carbon Isotopes; Chorea; Chromatography; Compulsive Behavior; Erythrocytes; Gout; Guanine; Guanine Nucleotides; Humans; Hypoxanthines; Intellectual Disability; Proteins; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Self Mutilation; Transferases; Uric Acid | 1970 |
Production of nucleic acid-related substances by fermentation processes. 33. Accumulation of inosine by a mutant of Brevibacterium ammoniagenes.
Topics: Adenine; Brevibacterium; Cell-Free System; Chromatography, Paper; Culture Media; Drug Resistance, Microbial; Fermentation; Genetics, Microbial; Guanine; Hypoxanthines; Ions; Manganese; Mutation; Nucleosides; Nucleotides; Purines; Spectrophotometry; Surface-Active Agents; Thioguanine; Time Factors | 1970 |
Phenolic content of sugarcane in relation to red rot disease.
Topics: Adenine; Animals; Carbon Isotopes; Cell Nucleus; Centrifugation, Density Gradient; Chlorides; Cytosine; Dactinomycin; Guanine; Hydrocortisone; Liver; Male; Manganese; Rats; RNA; RNA Nucleotidyltransferases; Stimulation, Chemical; Uracil; Uracil Nucleotides | 1970 |
Synthesis and storage of nucleotides in blood platelets.
Topics: Adenine; Animals; Blood Platelets; Carbon Isotopes; Centrifugation, Density Gradient; Chromatography; Guanine; In Vitro Techniques; Nucleosides; Nucleotides; Polynucleotides; Rabbits; Tritium; Vibration | 1970 |
Nutritional requirements for growth of Aerococcus viridans.
Topics: Adenine; Amino Acids; Bacteria; Biotin; Culture Media; Guanine; Nicotinic Acids; Pantothenic Acid; Surface-Active Agents; Xanthines | 1970 |
DNA methylation of T-even bacteriophages and of their nonglucosylated mutants: its role in P1-directed restriction.
Topics: Adenine; Chromatography, Paper; Coliphages; DNA, Viral; Filtration; Genetics, Microbial; Guanine; Methylation; Mutation; Spectrophotometry; Transferases; Tritium | 1970 |
Synthesis of RNA in developing rat brain in vitro.
Topics: Adenine; Adenine Nucleotides; Animals; Animals, Newborn; Brain; Carbon Isotopes; Cell Nucleus; Centrifugation; Chromatography; Cytoplasm; Dactinomycin; Guanine; In Vitro Techniques; Kinetics; Molecular Weight; Rats; RNA | 1970 |
Hypoxanthine phosphoribosyltransferase and guanine metabolism of adenocarcinoma 755 cells.
Topics: Adenine; Adenocarcinoma; Buffers; Carbon Isotopes; Guanine; Hydrogen-Ion Concentration; Hypoxanthines; In Vitro Techniques; Kinetics; Mercaptopurine; Neoplasms, Experimental; Nucleotides; Purines; Thioguanine; Transferases | 1970 |
[tRNA's from yeast having incorporated 5-fluorouracil arising from in vivo deamination of 5-fluorocytosine].
Topics: Adenine; Amino Acids; Aminohydrolases; Chromatography, Paper; Cytosine; Deamination; Fluorine; Fluorouracil; Guanine; Mutation; RNA, Transfer; Saccharomyces; Spectrophotometry; Ultraviolet Rays; Uracil | 1970 |
Alterations in the ribonucleic acids on digestion of liver microsomes with pancreatic ribonuclease.
Topics: Adenine; Animals; Centrifugation, Density Gradient; Chromatography, Ion Exchange; Cytosine; Guanine; HeLa Cells; Methods; Microsomes, Liver; Pancreas; Rabbits; Ribonucleases; RNA | 1970 |
A study of transfer RNA, toatl RNA and protein interrelationships in control and stressed isolated perfused rat hearts.
Topics: Adenine; Animals; Aorta, Thoracic; Coronary Circulation; DNA; Guanine; Guanosine; Heart; Ischemia; Leucine; Ligation; Male; Muscle Proteins; Myocardium; Myosins; Perfusion; Physical Exertion; Rats; RNA; RNA, Ribosomal; RNA, Transfer; Stress, Physiological; Tritium | 1970 |
Studies of the affinity of nuclear material for uroporphyrin. 3. Histones, nucleic acids, and bases.
Topics: Acetone; Adenine; Animals; Cattle; Chemical Precipitation; Chromatography, Gel; Cytosine; Dialysis; DNA; Fluorometry; Glutamates; Guanine; Histones; Humans; Hydrogen-Ion Concentration; Lysine; Peptides; Porphyrins; RNA; Saccharomyces; Serum Albumin; Spectrophotometry; Thymine; Thymus Gland; Uracil | 1970 |
Reversal of the growth inhibitory effects of 6-methylthiopurine ribonucleoside.
Topics: Adenine; Adenocarcinoma; Animals; Cell Division; Cell Line; Guanine; Hypoxanthines; Imidazoles; Mice; Nucleosides; Ribonucleosides; Sulfides | 1970 |
Fluorescence of the purine and pyrimidine bases of the nucleic acids in neutral aqueous solution at 300 degrees K.
Topics: Adenine; Cold Temperature; Cytosine; DNA; Energy Transfer; Fluorescence; Guanine; Photochemistry; Solutions; Spectrum Analysis; Uracil | 1971 |
Models of specifically paired like (homologous) nucleic acid structures.
Topics: Adenine; Cytosine; Guanine; Methods; Models, Chemical; Molecular Biology; Nucleic Acids; Protein Binding; Thymine; Uracil | 1971 |
Procedure for the base composition of RNA especially suited for samples containing relatively large amounts of DNA and protein.
Topics: Adenine; Chromatography, Ion Exchange; Cytosine; Cytosine Nucleotides; DNA; Guanine; Hydrogen-Ion Concentration; Hydrolysis; Methods; Nucleosides; Proteins; Purines; Pyrimidines; RNA; Serum Albumin, Bovine; Spectrophotometry; Temperature; Time Factors; Ultraviolet Rays; Uracil Nucleotides; Yeasts | 1971 |
Phosphoribosyl transferase activity in normal subjects, gout patients, and children with mental retardation.
Topics: Adenine; Adolescent; Adult; Child; Child, Preschool; Creatinine; Erythrocytes; Female; Gout; Guanine; Humans; Hypoxanthines; Intellectual Disability; Male; Metabolism, Inborn Errors; Radiochemistry; Transferases; Uric Acid | 1971 |
Purine base incorporation into erythrocyte nucleotides and erythrocyte phosphoribosyltransferase activity in primary gout.
Topics: Adenine; Adult; Aged; Erythrocytes; Glucose; Gout; Guanine; Humans; Hypoxanthines; Male; Middle Aged; Nucleotides; Purines; Transferases | 1971 |
Mass spectral analysis of modified ribonucleosides obtained by degradation of 14 alkali-stable dinucleotides isolated from yeast ribonucleic acid.
Topics: Adenine; Base Sequence; Chemical Phenomena; Chemistry; Cytosine; Glycosides; Guanine; Hydrogen-Ion Concentration; Mass Spectrometry; Methods; Methylation; Nucleosides; Pentoses; Polynucleotides; Ribonucleosides; RNA; Spectrum Analysis; Uridine; Yeasts | 1971 |
A simple paper chromatographic method for separation of methylated adenines and cytosine from the major bases found in nucleic acids.
Topics: Adenine; Base Sequence; Carbon Isotopes; Cellulose; Chromatography, Paper; Cytosine; DNA; Guanine; Hydrolysis; Methionine; Methods; Methylation; Nucleic Acids; Nucleotides; Phosphoric Acids; Purines; Pyrimidines; RNA; RNA, Ribosomal; Thymine; Tritium; Uracil | 1971 |
Isolation and characterization of epidermal DNA and RNA from guinea pig skin.
Topics: Adenine; Animals; Centrifugation, Density Gradient; Chemical Phenomena; Chemical Precipitation; Chemistry, Physical; Color; Cytosine; Densitometry; Deoxyribonucleases; DNA; Guanine; Guinea Pigs; Hydrolysis; Molecular Weight; Phosphorus; Ribonucleases; RNA; Skin; Spectrum Analysis; Thymine | 1971 |
Tissue-dependent differences in DNA methylation products of mice treated with methyl-labelled methylnitrosourea.
Topics: Adenine; Adenoma; Animals; Bone Marrow; Carbon Isotopes; DNA, Neoplasm; Guanine; Kidney; Liver; Lung; Lung Neoplasms; Lymphoma; Methylation; Mice; Neoplasms, Experimental; Nitroso Compounds; Spleen; Thymus Gland; Thymus Neoplasms; Urea | 1971 |
Indication of gene amplification in Rhynchosciara by RNA-DNA hybridization.
Topics: Adenine; Animals; Cytosine; Diptera; DNA; Female; Genes; Guanine; Hybridization, Genetic; Larva; Molecular Biology; Ovary; RNA; RNA, Ribosomal; Salivary Glands; Thymine; Tritium; Uracil | 1971 |
Pharmacology of captan: biochemical effects with special reference to macromolecular synthesis.
Topics: Adenine; Animals; Antifungal Agents; Candida; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cysteine; Depression, Chemical; DNA, Neoplasm; Drug Antagonism; Guanine; In Vitro Techniques; Indoles; Leucine; Macromolecular Substances; Neoplasm Proteins; RNA, Neoplasm; Serum Albumin, Bovine; Thymidine; Tritium; Uridine | 1971 |
Bacterial differentiation.
Topics: Adenine; Bacteria; Bacteriophages; Base Sequence; Cell Differentiation; Cell Division; Cytosine; Densitometry; DNA Viruses; DNA, Bacterial; DNA, Viral; Genetics, Microbial; Guanine; Microscopy, Electron; Morphogenesis; Recombination, Genetic; RNA Viruses; RNA, Bacterial; Thymine; Transduction, Genetic; Transformation, Genetic; Tritium | 1971 |
Control by feedback repression of the enzymes of purine biosynthesis in Aerobacter aerogenes.
Topics: Adenine; Adenine Nucleotides; Amino Sugars; Aspartic Acid; Cell-Free System; Enterobacter; Enzyme Repression; Feedback; Formates; Glutamine; Guanine; Guanine Nucleotides; Ligases; Lyases; Mutation; Nucleotides; Oxidoreductases; Pentosephosphates; Purines; Succinates; Transferases | 1971 |
Difference spectral studies on the interactions between ribonuclease T and its substrate analogues.
Topics: Adenine; Chemical Phenomena; Chemistry; Guanine; Hydrogen-Ion Concentration; Ribonucleases; Spectrophotometry | 1971 |
Purine nucleoside phosphorylase from human erythrocytes. V. Content and behavior of sulfhydryl groups.
Topics: Adenine; Benzoates; Carbon Isotopes; Chloromercuribenzoates; Detergents; Enzyme Activation; Erythrocytes; Guanine; Humans; Hypoxanthines; Kinetics; Molecular Weight; Nucleosides; Pentosephosphates; Phosphates; Protein Denaturation; Pyrimidines; Sulfhydryl Compounds; Sulfhydryl Reagents; Sulfides; Sulfuric Acids; Transferases | 1971 |
6-thioguanine: antimitotic effect on human lymphocytes in vitro prevented by adenine.
Topics: Adenine; Guanine; Humans; Hypoxanthines; In Vitro Techniques; Lectins; Lymphocyte Activation; Lymphocytes; Mitosis; Stimulation, Chemical; Thioguanine; Transferases | 1971 |
The separation of adenine and hypoxanthine-guanine phosphoribosyl transferases isoenzymes by disc gel electrophoresis.
Topics: Adenine; Animals; Child, Preschool; Electrophoresis, Disc; Erythrocytes; Guanine; Humans; Hypoxanthines; Isoenzymes; Lanthanum; Lesch-Nyhan Syndrome; Liver; Macaca; Male; Methods; Pentosephosphates; Sheep; Transferases | 1971 |
Metabolism of leptospires. II. The action of 8-azaguanine.
Topics: Adenine; Azaguanine; Carbon Isotopes; Glycine; Guanine; Leptospira; Leptospira interrogans; Palmitic Acids | 1967 |
Turnover of purine nucleotides in rabbit erythrocytes. I. Studies in vivo.
Topics: Adenine; Animals; Carbon Isotopes; Chromatography, Paper; Chromium Isotopes; Depression, Chemical; Erythrocytes; Glycine; Guanine; Hypoxanthines; Leucine; Nucleotides; Rabbits; Time Factors | 1967 |
Turnover of purine nucleotides in rabbit erythrocytes. II. Studies in vitro.
Topics: Adenine; Adenine Nucleotides; Animals; Carbon Isotopes; Chromatography, Paper; Electrophoresis; Erythrocytes; Feedback; Guanine; Guanine Nucleotides; Hydrogen-Ion Concentration; Hypoxanthines; Models, Biological; Nucleotides; Paper; Phosphates; Rabbits; Spectrophotometry; Stimulation, Chemical; Time Factors; Ultraviolet Rays; Xanthines | 1967 |
[Viral proteins, 3. On mutator mutants of the fd phage].
Topics: Acridines; Adenine; Coliphages; Cytosine; DNA Nucleotidyltransferases; DNA, Viral; Electrophoresis; Genetics, Microbial; Guanine; Molecular Biology; Mutagens; Mutation; Thymine; Viral Proteins | 1967 |
Biochemistry of the Salmonella. II. Metabolism of purine bases--adenine-8-C14 and guanine-8-C14 by Salmonella typhi, S. paratyphi A and S. paratyphi B under stationary condition of growth.
Topics: Adenine; Carbon Isotopes; Guanine; Salmonella; Salmonella paratyphi A; Salmonella typhi | 1967 |
[The electronic structure of pair bases of DNA in excited states, and Löwdin's mutation mechanism].
Topics: Adenine; Chemical Phenomena; Chemistry, Physical; Cytosine; DNA; Electrons; Guanine; Mutation; Thymine | 1967 |
[Variation in the ability to use exogenous purines in the biosynthesis of nucleic acids in various strains of the plague and pseudotuberculosis microbe].
Topics: Adenine; Carbon Isotopes; Culture Media; DNA, Bacterial; Guanine; Methods; Pasteurella; RNA, Bacterial | 1967 |
Isolation and partial characterization of nucleic acid of influenza virus.
Topics: Adenine; Animals; Centrifugation, Density Gradient; Chick Embryo; Chromatography; Culture Techniques; Cytosine; Genetics, Microbial; Guanine; Hemagglutination, Viral; Hemagglutinins, Viral; Horses; Orthomyxoviridae; Phosphorus Isotopes; RNA, Viral; Tritium; Uridine | 1967 |
Action of hydroxylamine on deoxyribonucleic acid in vitro.
Topics: Adenine; Animals; Cattle; Chemical Phenomena; Chemistry; Chromatography, Paper; Dialysis; DNA; Electrophoresis; Guanine; Hot Temperature; Hydrogen-Ion Concentration; Hydroxylamines; In Vitro Techniques; Kinetics; Molecular Weight; Mutagens; Spectrophotometry; Thymus Gland | 1967 |
[Primary structure of valine transfer RNA I of baker's yeast. Nucleotide content and oligonucleotides in ribonuclease hydrolysates].
Topics: Adenine; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Cytosine; Guanine; Ribonucleases; RNA, Transfer; Saccharomyces; Uracil | 1967 |
[Nucleotide content in the DNA of heterogametic strains of the fungus Blakeslea trispora].
Topics: Adenine; Chemical Phenomena; Chemistry; DNA; Fungi; Guanine; Thymine | 1967 |
Determination of the base composition of deoxyribonucleic acid by measurement of the adenine-granine ratio.
Topics: Adenine; Animals; Cattle; Chromatography, Ion Exchange; DNA; Guanine; Methods; Spectrophotometry; Thymus Gland | 1967 |
An enzymatic basis for variation in response to allopurinol. Hypoxanthine-guanine phosphoribosyltransferase deficiency.
Topics: Adenine; Adolescent; Adult; Aged; Allopurinol; Child; Creatinine; Glucosyltransferases; Gout; Guanine; Humans; Hypoxanthines; Male; Metabolism, Inborn Errors; Middle Aged; Purines; Uric Acid; Xanthines | 1968 |
Alterations in purine nucleotide biosynthesis induced by 2-amino-6-chloropurine.
Topics: Adenine; Adenine Nucleotides; Amides; Animals; Antineoplastic Agents; Carbon Isotopes; Chlorine; Female; Glycine; Guanine; Guanine Nucleotides; Hypoxanthines; Imidazoles; Iodine; Mice; Nucleic Acids; Nucleosides; Nucleotides; Oxidoreductases; Purines; Sarcoma 180; Xanthines | 1968 |
The chemical composition of the nucleic acids and the proteins of some mycoplasma strains.
Topics: Adenine; Amino Acids; Bacterial Proteins; Cytosine; DNA, Bacterial; Guanine; Mycoplasma; RNA, Bacterial; Thymine; Uracil | 1968 |
Purine metabolism in the chick embryo; effects of uricogenesis and xanthine oxidase inhibition.
Topics: Adenine; Amines; Animals; Carbon Isotopes; Chick Embryo; Formates; Glycine; Guanine; Nucleic Acids; Nucleotides; Purines; Pyrazoles; Pyrimidines; Thiazoles; Uric Acid; Xanthine Oxidase | 1968 |
Effects of exogenous purines on growth rates and other properties of Staphyloccus aureus strains including a pyrimidineless mutant of the Wood 46 strain.
Topics: Adenine; Guanine; Hypoxanthines; Mutation; Nucleosides; Purines; Staphylococcus; Thymine | 1968 |
Nuclear uptake of exogenous DNA by mammalian cells in culture.
Topics: Adenine; Animals; Carbon Isotopes; Cell Nucleus; Chromosomes; Culture Techniques; DNA; Guanine; Lymphoma; Statistics as Topic; Thymidine; Thymine; Tritium | 1968 |
Base composition of ribosomal RNA precursors in the HeLa cell nucleolus: further evidence of non-conservative processing.
Topics: Acrylic Resins; Adenine; Carbon Isotopes; Cell Nucleolus; Centrifugation, Zonal; Cytoplasm; Cytosine; Electrophoresis; Gels; Guanine; HeLa Cells; Phosphorus Isotopes; Ribosomes; RNA; Ultraviolet Rays; Uracil | 1968 |
Independent translation of the genes of bacteriophage f2 RNA.
Topics: Adenine; Adenine Nucleotides; Autoradiography; Carbon Isotopes; Coliphages; Genetics, Microbial; Guanine; Guanine Nucleotides; Histidine; Methionine; Methods; Mutation; Phenylalanine; Protein Biosynthesis; RNA, Messenger; RNA, Viral; Sulfur Isotopes; Tritium; Ultracentrifugation; Viral Proteins | 1968 |
The synthesis of one-carbon units from CO2 in Clostridium kluyveri.
Topics: Acetates; Adenine; Bicarbonates; Carbon Dioxide; Carbon Isotopes; Clostridium; Ethanol; Formates; Glycerol; Glycine; Guanine; Histidine; Methionine; Ribose; Serine; Thymine | 1968 |
[Effect of purines and pyrimidines on the growth of Corynebacterium sepedonicum (Spiek. & Kott.) Skapt. & Burkh].
Topics: Adenine; Corynebacterium; Cytosine; Guanine; Hypoxanthines; Purines; Pyrimidines; Thymine; Uracil; Xanthines | 1968 |
Effect of thyroid-stimulating hormone on ribonucleic acid synthesis in the calf thyroid in vitro in the presence of puromycin.
Topics: Adenine; Analysis of Variance; Animals; Carbon Isotopes; Cattle; Cell Nucleus; Cytoplasm; Formates; Glucose; Guanine; Hypoxanthines; In Vitro Techniques; Leucine; Protein Biosynthesis; Puromycin; RNA; Thyroid Gland; Thyrotropin | 1968 |
Reaction of nitrosoguanidine (N-methyl-N'-nitro-N-nitrosoguanidine) with tobacco mosaic virus and its RNA.
Topics: Adenine; Carbon Isotopes; Chemical Phenomena; Chemistry; Cytosine; Guanidines; Guanine; Methylation; Mutagens; Nitroso Compounds; Phosphorus Isotopes; Purines; Pyrimidines; RNA, Viral; Solutions; Tobacco Mosaic Virus; Uracil | 1968 |
Nucleotide metabolism in rat brain.
Topics: Adenine; Animals; Aspartic Acid; Carbon Isotopes; Cerebral Cortex; Chromatography, Paper; DNA; Glucosyltransferases; Glycine; Guanine; Hypoxanthines; In Vitro Techniques; Nerve Tissue Proteins; Nucleosides; Nucleotides; Orotic Acid; Oxidoreductases; Phosphotransferases; Rats; RNA; Uridine; Xanthine Oxidase; Xanthines | 1968 |
Competitive inhibition of adenosine deaminase by purine and pyrimidine bases.
Topics: Adenine; Aminohydrolases; Guanine; Hypoxanthines; Kinetics; Nucleosides; Purines; Pyrimidines; Xanthines | 1968 |
A two-dimensional thin-layer chromatographic technique for the separation of admixtures of 5-bromouracil and DNA bases.
Topics: Adenine; Bromine; Chromatography, Thin Layer; Cytosine; DNA; Guanine; Methods; Thymine; Uracil | 1968 |
Biochemical bases of accelerated purine biosynthesis de novo in human fibroblasts lacking hypoxanthine-guanine phosphoribosyltransferase.
Topics: Adenine; Adenine Nucleotides; Adolescent; Adult; Athetosis; Biopsy; Carbon Isotopes; Child; Child, Preschool; Chorea; Chromatography, Gel; Culture Techniques; Feedback; Female; Fibroblasts; Formates; Guanine; Guanine Nucleotides; Humans; Hypoxanthines; Intellectual Disability; Male; Mercaptopurine; Nucleotides; Purines; Self Mutilation; Spasm; Transferases; Tritium | 1968 |
Absence of nucleotide sequence complementarity between Sindbis virus and Newcastle disease virus genomes.
Topics: Adenine; Animals; Centrifugation, Density Gradient; Chemical Phenomena; Chemistry; Chick Embryo; Culture Techniques; Cytopathogenic Effect, Viral; Cytosine; Encephalitis Viruses; Genetics, Microbial; Guanine; Molecular Biology; Newcastle disease virus; Nucleotides; RNA, Viral; Tritium; Uracil | 1968 |
Ion induced coil to helix transition of dialyzed poly d(A-T) from Cancer borealis.
Topics: Adenine; Animals; Calcium; Chemical Phenomena; Chemistry, Physical; Chromatography; Crustacea; Cytosine; Dialysis; DNA; Guanine; Hydrogen-Ion Concentration; Magnesium; Male; Microscopy, Electron; Photomicrography; RNA; Spectrophotometry; Testis; Thymine | 1968 |
The determination of base ratios of very small samples of ribonucleic acid using thin layer chromatography.
Topics: Adenine; Cellulose; Chromatography, Thin Layer; Cytosine Nucleotides; Guanine; RNA; Spectrophotometry; Thymine; Uracil Nucleotides | 1968 |
Comparative electrophoresis of cytidines, adenines, uracils and guanines.
Topics: Adenine; Electrophoresis; Guanine; Hydrogen-Ion Concentration; Nucleosides; Uracil; Uric Acid | 1968 |
Ultraviolet microscopy of purines and amino acids in the vacuole of Candida albicans.
Topics: Adenine; Amino Acids; Candida; Culture Media; Cytoplasm; Guanine; Microscopy; Purines; Pyrimidines; Spectrophotometry; Tyrosine; Ultraviolet Rays; Uric Acid; Xanthines | 1968 |
Methylated bases in liver acids from rats treated with dimethylnitrosamine.
Topics: Adenine; Animals; Autoradiography; Carbon Isotopes; Chromatography, Paper; Cytosine; DNA; Guanine; Liver; Male; Methylation; Nitrosamines; Rats; RNA | 1968 |
On the hydration of DNA. II. Base composition dependence of the net hydration of DNA.
Topics: Adenine; Centrifugation, Density Gradient; Chemical Phenomena; Chemistry; Cytosine; DNA, Bacterial; Guanine; Thymine; Water | 1968 |
Relative reactivities for monofunctional nitrogen mustard alkylation of nucleic acid components.
Topics: Adenine; Alkylation; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Chromatography, Paper; DNA; Guanine; Kinetics; Magnetic Resonance Spectroscopy; Nitrogen Mustard Compounds; Nucleic Acid Denaturation; Nucleosides; Spectrum Analysis; Temperature; Thymidine; Thymine; Time Factors | 1968 |
Optical rotatory dispersion, tryptophan location, and base distribution in tobacco moscic virus.
Topics: Adenine; Chemical Phenomena; Chemistry; Guanine; Nucleotides; Optical Rotatory Dispersion; Polymers; RNA, Viral; Time Factors; Tobacco Mosaic Virus; Tryptophan; Ultracentrifugation; Viral Proteins | 1968 |
The pathway of catabolism of cytotoxic purinyl-6-substituted amines in vivo.
Topics: Adenine; Amines; Animals; Antineoplastic Agents; Carbon Dioxide; Carbon Isotopes; Chromatography; Female; Guanine; Histamine; Mice; Purines; Time Factors | 1968 |
Mode of action of alanosine.
Topics: Adenine; Animals; Antifungal Agents; Antiviral Agents; Aspartic Acid; Azaserine; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Depression, Chemical; Formates; Glutamine; Glycine; Guanine; Leucine; Nitrosamines; Nucleotides; Propionates; RNA, Neoplasm; Thymidine; Tritium; Uridine | 1968 |
RNA metabolism of fertilized Ascaris lumbricoides eggs during uterine development.
Topics: Adenine; Ascaris; DNA; Embryo, Nonmammalian; Female; Fertilization; Guanine; Microscopy, Electron; Ovum; Phosphorus Isotopes; Pregnancy; Protein Biosynthesis; RNA; Templates, Genetic; Tritium; Uridine; Uterus | 1968 |
Nucleic acids of bovine lymphosarcoma and normal thymus.
Topics: Adenine; Animals; Carbon Isotopes; Cattle; Cytosine; DNA, Neoplasm; Electrophoresis; Guanine; Lymphoma, Non-Hodgkin; Nucleic Acids; RNA, Neoplasm; Spectrophotometry; Thymine; Thymus Gland | 1968 |
Biochemistry of Friend virus-infected cells. I. Virion-specific RNA.
Topics: Adenine; Animals; Carbon Isotopes; Centrifugation, Density Gradient; Choline; Cytosine; Friend murine leukemia virus; Genetics, Microbial; Guanine; Leucine; Lipids; Mice; Phosphorus Isotopes; Ribosomes; RNA, Transfer; RNA, Viral; Spleen; Tritium; Uracil; Viral Proteins | 1968 |
[Studies on the alkylating effect of 14C-methylnitrosourea and 1-14C-ethylnitrosurea].
Topics: Adenine; Alkylating Agents; Alkylation; Animals; Brain; Carbon Isotopes; Chromatography, Ion Exchange; Cytosine Nucleotides; Guanine; Kidney; Liver; Male; Nitroso Compounds; Purines; Rats; RNA; Uracil Nucleotides; Urea | 1968 |
Accelerated purine biosynthesis de novo in skin fibroblasts deficient in hypoxanthine--guanine phosphoribosyltransferase activity.
Topics: Adenine; Adenine Nucleotides; Carbon Isotopes; Depression, Chemical; Erythrocytes; Feedback; Fibroblasts; Formates; Guanine; Humans; Hypoxanthines; Mercaptopurine; Metabolic Diseases; Nucleosides; Purines; Skin; Stimulation, Chemical; Transferases; Tritium | 1968 |
Effect of erythropoietin on nucleic acid metabolism from polycythemic rat bone marrow.
Topics: Adenine; Animals; Bone Marrow; Carbon Isotopes; DNA; Erythropoietin; Formates; Guanine; Polycythemia; Rats; RNA; Thymine | 1968 |
[The effect of iron on the purine metabolism and the formation of riboflavin of Candida guiliermondii (Cast.) Lang. et G].
Topics: Adenine; Candida; Carbon Isotopes; Glycine; Guanine; Hypoxanthines; Iron; Proteins; Purines; Riboflavin; RNA; Uric Acid; Xanthines | 1968 |
3 nuclear RNA fractions and their relationship to polysomal mRNA.
Topics: Adenine; Animals; Cell Nucleus; Cytosine; Guanine; Hybridization, Genetic; Liver; Liver Extracts; Orotic Acid; Phosphorus Isotopes; Rats; Ribosomes; RNA; RNA, Messenger; Tritium; Uracil | 1968 |
Infrared spectrum of deoxyribonucleic acid. Effects of base composition and of N15-substitution.
Topics: Adenine; Chemical Phenomena; Chemistry; Cytosine; DNA; DNA, Bacterial; Guanine; Infrared Rays; Nitrogen; Radioisotopes; Spectrum Analysis; Thymine | 1968 |
Purine and pyrimidine synthesis by the avian malaria parasite, Plasmodium lophurae.
Topics: Adenine; Animals; Bicarbonates; Carbon Isotopes; Cytosine; Ducks; Erythrocytes; Formates; Guanine; Ligases; Malaria, Avian; Plasmodium; Purines; Pyrimidines; Thymine; Transferases; Uracil | 1968 |
Theory of thermal transitions in low molecular weight RNA chains.
Topics: Adenine; Alanine; Chemical Phenomena; Chemistry, Physical; Cytosine; Guanine; Models, Structural; Molecular Weight; RNA; Thermodynamics; Tyrosine; Uracil | 1968 |
Physicochemical studies on x-ray inactivation of bacteriophage.
Topics: Adenine; Coliphages; Cytopathogenic Effect, Viral; Cytosine; DNA, Viral; Guanine; Molecular Weight; Radiation Genetics | 1968 |
Ribosomal binding of AUG by formyl-methionyl-sRNA.
Topics: Adenine; Formates; Guanine; Kinetics; Magnesium; Methionine; Phosphorus Isotopes; Polynucleotides; Ribosomes; RNA, Transfer; Sulfur Isotopes; Uracil | 1968 |
On the mechanism of mutagenic action of hydroxylamine.
Topics: Adenine; Cytosine; DNA Replication; Guanine; Hydroxylamines; Molecular Biology; Mutagens; Mutation; Quantum Theory; Thymine | 1968 |
An examination of the energetics of Crick's wobble hypothesis.
Topics: Adenine; Amino Acid Sequence; Cytosine; Energy Transfer; Genetic Code; Guanine; Models, Biological; Uracil | 1968 |
Iterative extended Hückel study of nucleic acid bases.
Topics: Adenine; Chemical Phenomena; Chemistry; Cytosine; Guanine; Mathematics; Thymine; Uracil | 1968 |
[Quantitative estimation of RNA and DNA contents in mammalian organs].
Topics: Adenine; Adenine Nucleotides; Animals; Brain Chemistry; Cats; Chromatography, Ion Exchange; Cytosine; Cytosine Nucleotides; DNA; Dogs; Guanine; Guanine Nucleotides; Kidney; Liver; Male; Myocardium; Pancreas; Rabbits; Rats; RNA; Testis | 1968 |
[Nucleic acid metabolism of leukemic leukocytes. 2. The effect of 6-mercaptopurine on nucleic acid metabolism of leukemic leukocytes].
Topics: Adenine; Carbon Isotopes; Guanine; Humans; Hypoxanthines; Leukemia; Leukocytes; Mercaptopurine; Nucleic Acids; Purines | 1968 |
Influence of aminopterin administration to dams upon single carbon transfer into purines of fetal brains.
Topics: Adenine; Aminopterin; Animals; Brain; Carbon Isotopes; Female; Fetus; Formates; Gestational Age; Guanine; Histidine; Injections, Intraperitoneal; Maternal-Fetal Exchange; Pregnancy; Purines; Rats; Serine | 1968 |
A new technique of pH gradient electrophoresis as applied to the separation of nucleic acid bases.
Topics: Adenine; Cytosine; Electrophoresis; Guanine; Hydrogen-Ion Concentration; Methods; Thymine; Uracil | 1968 |
Hypoxanthine-guanine phosphoribosyltransferase: further evidence for the identity of the binding sites for hypoxanthine and guanine.
Topics: Adenine; Adenine Nucleotides; Binding Sites; Carbon Isotopes; Dialysis; Erythrocytes; Guanine; Guanine Nucleotides; Hemolysis; Humans; Hypoxanthines; Inositol; Nucleotides; Transferases | 1969 |
Purines: active transport by isolated choroid plexus.
Topics: Adenine; Allopurinol; Animals; Biological Transport, Active; Blood-Brain Barrier; Choroid Plexus; Female; Guanine; Hypoxanthines; In Vitro Techniques; Kinetics; Purines; Rabbits; Uracil; Uric Acid; Xanthines | 1969 |
Reaction of nitrous acid with alkylaminopurines.
Topics: Adenine; Chemical Phenomena; Chemistry; Guanine; Nitrites; Nitroso Compounds; Purines; Spectrophotometry | 1969 |
The effects of intermedin on the ultrastructure of amphibian iridophores.
Topics: Adenine; Amphibians; Animals; Anura; Chromatophores; Guanine; Hypoxanthines; Melanocyte-Stimulating Hormones; Microscopy, Electron | 1969 |
Studies on ribosomal RNA structure. II. Secondary structures in solution of rRNA and crystallizable fragments.
Topics: Adenine; Chemical Phenomena; Chemistry; Crystallization; Cytosine; Deuterium; Guanine; Hot Temperature; Infrared Rays; Nucleic Acid Denaturation; Nucleosides; Reticulocytes; Ribosomes; RNA; RNA, Transfer; Saccharomyces; Spectrophotometry; Tobacco Mosaic Virus; Ultraviolet Rays; Uracil; X-Ray Diffraction | 1969 |
Glycine-C-14 incorporation into nucleic acid purine by leucocytes obtained from normal and gouty subjects.
Topics: Adenine; Carbon Isotopes; Cyanides; Depression, Chemical; DNA; Female; Glycine; Gout; Guanine; Humans; Hypoxanthines; In Vitro Techniques; Iodoacetates; Leukocytes; Male; Purines; RNA; Uric Acid | 1969 |
Base composition of DNA from chloroplasts and nuclei of Phaseolus vulgaris.
Topics: Adenine; Cell Nucleus; Chloroplasts; Chromatography, Ion Exchange; Cytosine; DNA; Guanine; Plants, Edible; Pyrimidines | 1969 |
Rapid column chromatographic determination of ribonucleotides in soup preparations.
Topics: Adenine; Chromatography, Ion Exchange; Creatinine; Food Analysis; Guanine; Hypoxanthines; Meat; Nucleotides; Yeasts | 1969 |
An infrared study of the hydrogen-bonding specificity of hypoxanthine and other nucleic acid derivatives.
Topics: Adenine; Chemical Phenomena; Chemistry; Cytosine; Guanine; Hydrogen; Hypoxanthines; Infrared Rays; Spectrum Analysis; Thermodynamics; Thymine; Uracil | 1969 |
Gene duplication and nucleotide substitution in evolution.
Topics: Adenine; Animals; Biological Evolution; Cytosine; DNA; Genetic Code; Genetics, Population; Guanine; Molecular Biology; Mutation; Nucleotides; Peptide Biosynthesis; Polyploidy; Probability; Thymine; Vertebrates | 1969 |
A new disorder of purine metabolism with behavioral manifestations.
Topics: Adenine; Allopurinol; Autistic Disorder; Carbon Isotopes; Child Behavior Disorders; Child, Preschool; Erythrocytes; Glucosyltransferases; Glycine; Gout; Guanine; Humans; Hypoxanthines; Intellectual Disability; Male; Mutism; Nucleotides; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Uric Acid; Xanthenes | 1969 |
Study of the methylation and lack of deamination of deoxyribonucleic acid by N-methyl-N'-nitro-N-nitrosoguanidine.
Topics: Adenine; Animals; Animals, Newborn; Carbon Isotopes; Chemical Phenomena; Chemistry; Cysteine; DNA; Female; Guanidines; Guanine; Hypoxanthines; Methylation; Nitroso Compounds; Rats; Xanthines | 1969 |
Deoxyribonucleic acid base composition and homology studies of Leptospira.
Topics: Adenine; Agglutination Tests; Chemical Phenomena; Chemistry, Physical; Cytosine; DNA, Bacterial; Guanine; Leptospira; Nucleic Acid Denaturation; Serotyping; Tritium | 1969 |
[Comparison of pyrimidine sequences from different insect DNA's].
Topics: Adenine; Animals; Bees; Biological Evolution; Bombyx; Cytosine; Diptera; DNA; Guanine; Insecta; Male; Nucleotides; Pyrimidines; Species Specificity; Thymine | 1969 |
The DNA base composition of individual chromosomes and chromosome segments from Chironomus tentans.
Topics: Adenine; Animals; Chromosomes; Cytosine; Diptera; DNA; Electrophoresis; Guanine; Micromanipulation | 1969 |
Role of extracellular ribonuclease in growth of Corynebacterium acnes.
Topics: Adenine; Colorimetry; Corynebacterium; Culture Media; Cytosine; Guanine; Nucleotides; Ribonucleases; RNA; Xanthines | 1969 |
Rapid analysis of ribonucleosides and bases at the picomole level using pellicular cation exchange resin in narrow bore columns.
Topics: Adenine; Chromatography, Ion Exchange; Guanine; Hydrogen-Ion Concentration; Microchemistry; Nucleosides; Temperature; Uracil | 1969 |
Nuclear magnetic resonance studies of the interaction of chloroquine diphosphate with adenosine 5'-phosphate and other nucleotides.
Topics: Adenine; Adenine Nucleotides; Chemical Phenomena; Chemistry; Chloroquine; Cytosine; Guanine; Magnetic Resonance Spectroscopy; Protons; Spectrum Analysis; Temperature; Thymine | 1969 |
The inhibition of nucleic acid synthesis by mycophenolic acid.
Topics: Adenine; Animals; Antibiotics, Antineoplastic; Caproates; DNA, Neoplasm; Guanine; Guanine Nucleotides; Hypoxanthines; In Vitro Techniques; L Cells; Mercaptopurine; Mice; Neoplasms, Experimental; Oxidoreductases; Rats; Sarcoma, Yoshida; Thymidine | 1969 |
Poly-N-vinyl pyrrolidone chromatography. Effect of pH on elution of bases and a proposed mechanism for the adsorption of purines.
Topics: Adenine; Adsorption; Chromatography; Cytosine; Guanine; Hydrogen-Ion Concentration; Povidone; Purines; Thymine | 1969 |
Chemical modification of viral ribonucleic acid. VII. The action of methylating agents and nitrosoguanidine on polynucleotides including tobacco mosaic virus ribonucleic acid.
Topics: Adenine; Alkylating Agents; Chemical Phenomena; Chemistry; Chromatography, Paper; Cytosine; Guanidines; Guanine; Nitroso Compounds; Nucleotides; Polynucleotides; Purines; RNA, Viral; Spectrophotometry; Sulfates; Sulfonic Acids; Tobacco Mosaic Virus | 1969 |
Chemical modification of viral ribonucleic acid. 8. The chemical and biological effects of methylating agents and nitrosoguanidine on tobacco mosaic virus.
Topics: Adenine; Alkylating Agents; Carbon Isotopes; Cytosine; Guanidines; Guanine; Methylation; Mutation; Nitroso Compounds; RNA, Viral; Temperature; Time Factors; Tobacco Mosaic Virus | 1969 |
[Some aspects of radio-denaturation of various nucleic components. I. Radio-denaturation of purine and pyrimidine bases].
Topics: Adenine; Chemical Phenomena; Chemistry; Cobalt Isotopes; Cytosine; Guanine; Hydrogen-Ion Concentration; Purines; Pyrimidines; Radiation Effects; Spectrophotometry; Thymine | 1969 |
[Some aspects of the radio-denaturation of various nucleic components. II. Radio-denaturation of deoxynucleosides of DNA].
Topics: Adenine; Adenine Nucleotides; Chemical Phenomena; Chemistry; Cobalt Isotopes; Cytosine; DNA; Guanine; Hydrogen-Ion Concentration; Nucleosides; Purines; Pyrimidines; Radiation Effects; Spectrophotometry; Thymine | 1969 |
Interaction of oxidized polyamines with DNA. 3. Association with nucleosides, mono- and polynucleotides.
Topics: Adenine; Adenine Nucleotides; Aldehydes; Amines; Animals; Carbon Isotopes; Cattle; Chemical Phenomena; Chemistry; Cytosine; DNA; Electrophoresis; Guanine; Guanine Nucleotides; Imines; Nucleic Acid Denaturation; Nucleosides; Nucleotides; Polynucleotides; Spectrophotometry; Spermine; Thymine; Thymus Gland; Tritium; Uracil | 1969 |
Base alterations of nucleic acids in stomach wall after prolonged atropine treatment.
Topics: Adenine; Animals; Atropine; Chromatography, Paper; Cytosine; DNA; Gastric Mucosa; Guanine; Purines; Pyrimidines; Rats; RNA; Spectrophotometry; Thymine; Uracil | 1969 |
Linear regression on proportions.
Topics: Adenine; Cytosine; Densitometry; DNA; Guanine; Statistics as Topic; Thymine | 1969 |
Charge transfer between nucleic acid bases and chloranil.
Topics: Adenine; Chemical Phenomena; Chemistry; Cytosine; Guanine; Quinones; Solubility; Solutions; Spectrophotometry; Thymine | 1965 |
Studies on the properties of factors elevating the activity of mouse-plasma lactate dehydrogenase.
Topics: Adenine; Animals; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Enzymes; Guanine; In Vitro Techniques; L-Lactate Dehydrogenase; Mice; Nucleosides; Oncogenic Viruses; RNA; Sarcoma 180; Uridine | 1964 |
Turnover of nucleic acids in a multiplying animal cell. 2. Retention studies.
Topics: Adenine; Cell Division; Cell Nucleus; Culture Techniques; Cytoplasm; Guanine; HeLa Cells; Macrophages; Nucleosides; Phosphates; Phosphorus Isotopes; RNA; Uracil Nucleotides | 1964 |
Binding of purines and pyrimidines by bentonite, an inhibitor of nucleases.
Topics: Adenine; Aluminum Silicates; Chemical Phenomena; Chemistry; Cytosine; Enzymes; Guanine; Hypoxanthines; Nucleosides; Xanthines | 1965 |
Ribonucleic acid base composition in the developing amphibian optic cup-lens system.
Topics: Adenine; Animals; Anura; Cell Differentiation; Chemical Phenomena; Chemistry; Embryo, Nonmammalian; Eye; Guanine; Lens, Crystalline; Nucleosides; RNA; Uridine | 1965 |
Studies on the nuclear and nucleolar ribonucleic acid of regenerating rat liver.
Topics: Adenine; Animals; Cell Nucleolus; Cell Nucleus; Chemistry Techniques, Analytical; Cytosine; Guanine; Hepatectomy; In Vitro Techniques; Liver; Liver Regeneration; Orotic Acid; Phosphates; Rats; RNA; Ultracentrifugation; Uracil | 1965 |
Purine N-oxides. XVI. Oncogenic derivatives of xanthine and guanine.
Topics: Adenine; Adenocarcinoma; Animals; Carcinogens; Carcinoma, Squamous Cell; Female; Fibroblasts; Fibrosarcoma; Guanine; Liposarcoma; Mammary Neoplasms, Experimental; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Rhabdomyosarcoma; Xanthines | 1965 |
Effect of 8-azaguanine on phosphorylation of purines in Astasia and Euglena.
Topics: Adenine; Azaguanine; Euglena; Eukaryota; Guanine; Hypoxanthines; In Vitro Techniques; Nucleotides; Phosphates; Phosphotransferases; Trichloroacetic Acid | 1965 |
[Comparative study of 2 fractions of ribosomal RNA from animal cells].
Topics: Adenine; Animals; Chemical Phenomena; Chemistry; Cricetinae; Culture Techniques; Cytosine; Fibroblasts; Guanine; Kidney; Liver; Mice; Phosphorus Isotopes; Physiology, Comparative; Poultry; Rats; Ribosomes; RNA; Uracil | 1965 |
Base composition of messenger RNA of Pseudomonas effusa irradiated with ultraviolet light.
Topics: Adenine; Cytosine; Guanine; In Vitro Techniques; Pseudomonas; Radiochemistry; RNA, Bacterial; RNA, Messenger; Uracil | 1965 |
Determination of base sequence in nucleic acids with the electron microscope. IV. Nucleoside complexes with certain metal ions.
Topics: Adenine; Chemical Phenomena; Chemistry, Physical; Copper; Cytosine; Guanine; Hydrogen-Ion Concentration; Lead; Microscopy, Electron; Nucleosides; Spectrophotometry; Thymine; Uracil | 1965 |
Evidence for carrier-mediated transport of adenine by isolated rat liver nuclei.
Topics: Adenine; Animals; Biological Transport; Cell Nucleus; Guanine; In Vitro Techniques; Liver; Rats | 1965 |
Equilibrium constants for association of actinomycin D with several purine derivatives.
Topics: Adenine; Adenine Nucleotides; Chemical Phenomena; Chemistry; Dactinomycin; Guanine; Guanine Nucleotides; Spectrophotometry | 1965 |
Alteration of hamster cells by nucleic acid in vitro.
Topics: Adenine; Animals; Clone Cells; Cricetinae; Culture Techniques; Cytosine; DNA; Fibroblasts; Guanine; Kidney; Microscopy, Interference; Ribonucleases; RNA; Uracil | 1965 |
Studies on RNA synthesis in chloroplast preparations.
Topics: Adenine; Chloroplasts; DNA; Guanine; In Vitro Techniques; Magnesium; Manganese; Plants, Edible; RNA | 1964 |
Mutagenicity of cytosine for an adenine and arginine requiring strain of Candida albicans.
Topics: Adenine; Arginine; Candida; Cytosine; Guanine; Mutagens | 1965 |
The utilization of purines and their ribosyl derivatives for the formation of adenosine triphosphate and guanosine triphosphate in the rabbit reticulocyte.
Topics: Adenine; Adenosine Triphosphate; Animals; Anti-Bacterial Agents; Diazooxonorleucine; Guanine; Guanine Nucleotides; Hypoxanthines; In Vitro Techniques; Nucleosides; Purines; Rabbits; Reticulocytes; Xanthines | 1966 |
Microchemical fractionation of neuronal and glial RNA.
Topics: Adenine; Animals; Brain Chemistry; Chemistry Techniques, Analytical; Cytosine; Guanine; In Vitro Techniques; Microchemistry; Neuroglia; Neurons; Rabbits; RNA; Uracil | 1966 |
Origin of urinary methylated purines.
Topics: Adenine; Animals; Carbon Isotopes; Guanine; Humans; Lymphoma; Male; Mammary Neoplasms, Experimental; Methionine; Mice; Rats; Xanthines | 1966 |
A comparison between RNA metabolism of nerve cells and glia in the hypoglossal nucleus of the rabbit.
Topics: Adenine; Animals; Cytosine; Electrophoresis; Guanine; Histocytochemistry; Hypoglossal Nerve; In Vitro Techniques; Medulla Oblongata; Neuroglia; Neurons; Nucleosides; Pons; Rabbits; RNA; Tritium; Uracil | 1966 |
Biochemical studies with the vinca alkaloids. II. Effect of vinblastine on the biosynthesis of nucleic acids and their precursors in rat thymus cells.
Topics: Adenine; Animals; Aspartic Acid; Carbon Isotopes; Chromatography, Ion Exchange; DNA; Formates; Glutamine; Glycine; Guanine; Hypoxanthines; In Vitro Techniques; Rats; RNA; Serine; Spectrophotometry; Thymine; Thymus Gland; Vinblastine; Xanthines | 1966 |
Inhibition by adenine of Staphylococcus aureus growth in a nutrient medium free from guanine, guanosine, or hypoxanthine.
Topics: Adenine; Guanine; Hypoxanthines; In Vitro Techniques; Nucleosides; Staphylococcus | 1966 |
Double-stranded ribonucleic acid from rice dwarf virus.
Topics: Adenine; Chromatography, Paper; Cytosine; Formaldehyde; Guanine; Hot Temperature; In Vitro Techniques; Microscopy, Electron; Oryza; Plant Viruses; Ribonucleases; RNA; RNA, Transfer; RNA, Viral; Spectrum Analysis; Ultracentrifugation; Uracil | 1966 |
Determination of nucleic acid base ratios by gas-liquid chromatography.
Topics: Adenine; Chemical Phenomena; Chemistry; Chromatography, Gas; Cytosine; Guanine; RNA; Uracil | 1966 |
Some aspects of pteridine biosynthesis in amphibians.
Topics: Adenine; Animals; Anura; Chromatography, Paper; Glycine; Guanine; Hypophysectomy; Hypoxanthines; In Vitro Techniques; Pteridines; Subcellular Fractions | 1966 |
[Thin-layer chromatographic separation of some purine derivatives, including uric acid].
Topics: Adenine; Caffeine; Chromatography, Thin Layer; Guanine; Hypoxanthines; Purines; Theobromine; Theophylline; Uric Acid; Xanthines | 1966 |
RNA composition and base pairing.
Topics: Adenine; Chemical Phenomena; Chemistry; Guanine; Purines; Pyrimidines; RNA | 1966 |
Tryptophan pyrrolase activity: effects of cyclic-AMP, purines, pyrimidines, nucleosides, and nucleotides.
Topics: Adenine; Adenine Nucleotides; Animals; Ascorbic Acid; Cytosine; Cytosine Nucleotides; Guanine; Guanine Nucleotides; Heme; In Vitro Techniques; Liver; Nucleosides; Oxygenases; Rats; Subcellular Fractions; Tryptophan Oxygenase; Uracil; Uracil Nucleotides | 1966 |
The relationship between cellular nucleic acids in the developing rat cerebral cortex.
Topics: Adenine; Animals; Animals, Newborn; Brain Chemistry; Cell Nucleus; Cerebral Cortex; Cytosine; DNA; Guanine; In Vitro Techniques; Microsomes; Orotic Acid; Rats; Ribosomes; RNA; Subcellular Fractions; Uracil | 1966 |
Base composition of messenger RNA from rabbit reticulocytes.
Topics: Adenine; Animals; Centrifugation; Chemical Phenomena; Chemistry; Cytosine; Guanine; In Vitro Techniques; Rabbits; Reticulocytes; RNA, Messenger; Spectrophotometry; Uracil | 1966 |
Availability of bases and nucleosides as precursors of nucleic acids in L cells and in the agent of meningopneumonitis.
Topics: Adenine; Chlamydia; Culture Techniques; DNA; DNA, Viral; Guanine; L Cells; Nucleosides; RNA; RNA, Viral; Thymidine; Tritium; Uridine | 1966 |
Base composition of ribosomal ribonucleic acid in newborn and adult rat brain.
Topics: Adenine; Animals; Animals, Newborn; Brain; Brain Chemistry; Cytosine; Guanine; In Vitro Techniques; Memory; Rats; Ribosomes; RNA; Uracil | 1966 |
Base composition of fractions of nuclear and nucleolar ribonucleic acid obtained by sedimentation and chromatography.
Topics: Adenine; Animals; Cell Nucleus; Chemical Phenomena; Chemistry; Cytosine; Guanine; In Vitro Techniques; Liver; Rats; RNA; Uracil | 1966 |
A bacteriophage for Myxococcus xanthus: isolation, characterization and relation of infectivity to host morphogenesis.
Topics: Adenine; Adsorption; Animals; Bacteria; Bacteriophages; Calcium; Cattle; Cytosine; DNA, Viral; Feces; Glycerol; Guanine; In Vitro Techniques; Microscopy, Electron; Mutation; Thymine | 1966 |
Anomalous electrophoretic behavior of purine and pyrimidine derivatives in triethylammonium buffers.
Topics: Acetates; Adenine; Bicarbonates; Buffers; Carbonates; Cytosine; Formates; Guanine; Purines; Pyrimidines; Quaternary Ammonium Compounds; Thymine; Uracil; Uracil Nucleotides; Uridine; Xanthines | 1966 |
Changes in RNA synthesis following transfer of Sarcoma 180 ascites cells from the mouse to synthetic medium.
Topics: Adenine; Animals; Chromatography; Culture Techniques; Cytosine; Guanine; Mice; Phosphorus Isotopes; RNA, Neoplasm; Sarcoma 180; Spectrophotometry; Tritium; Uridine | 1966 |
Non-randomness in base sequences of DNAs.
Topics: Adenine; Animals; Biometry; Cattle; Chemical Phenomena; Chemistry; Cytosine; DNA; Guanine; In Vitro Techniques; Thymine; Thymus Gland | 1966 |
Composition of the nucleolus as a basis for views on its function.
Topics: Adenine; Cell Nucleolus; Chromosomes; Cytosine; Diptera; DNA; Drosophila; Electrophoresis; Guanine; Microchemistry; Phosphorus Isotopes; RNA; RNA, Messenger; Uracil | 1966 |
Structure of nucleohistone. II. Thermal denaturation.
Topics: Adenine; Chemical Phenomena; Chemistry, Physical; Cytosine; DNA; Guanine; Histones; Hot Temperature; Thymine | 1966 |
Studies on the metabolic fate of the C14 labeled methyl group of a methylhydrazine derivative in P815 mouse leukemia.
Topics: Adenine; Alkylation; Animals; Carbon Isotopes; DNA; Formates; Guanine; Hydrazines; Hypoxanthines; Leukemia, Experimental; Mice | 1966 |
Loss of adenine during the hydrazine degradation of deoxyribonucleic acid.
Topics: Adenine; Animals; Cattle; Chemical Phenomena; Chemistry; Chromatography, Paper; Cytosine; DNA; Guanine; Hydrazines; Hydroxides; Pyrimidines; Temperature; Thymine | 1966 |
Newcastle disease virus RNA. I. Isolation and preliminary characterization of RNA from virus particles.
Topics: Adenine; Centrifugation, Density Gradient; Chromatography, Gel; Cytosine; Detergents; Guanine; Newcastle disease virus; Phenols; RNA, Viral; Spectrophotometry; Uracil | 1966 |
Newcastle disease virus RNA. II. Preferential synthesis of RNA complementary to parental viral RNA by chick embryo cells.
Topics: Adenine; Animals; Chick Embryo; Culture Techniques; Cytosine; Dactinomycin; Deoxyribonucleases; Guanine; Hot Temperature; Newcastle disease virus; Nucleic Acid Denaturation; Phosphorus Isotopes; Ribosomes; RNA; RNA, Viral; Tritium; Uracil; Uridine | 1966 |
Feasibility of obtaining Raman spectra from nucleic acid constituents.
Topics: Adenine; Adenine Nucleotides; Cytosine; Guanine; Nucleosides; Spectrophotometry; Thymidine; Uridine | 1966 |
On the hydrogen bonding scheme between purines and pyrimidines.
Topics: Adenine; Chemical Phenomena; Chemistry, Physical; Cytosine; Guanine; Thymine | 1966 |
Comparison of physicochemical properties of mitochondrial and nuclear deoxyribonucleic acid from rat liver cells.
Topics: Adenine; Animals; Cell Nucleus; Chromatography, Paper; Cytosine; DNA; Guanine; In Vitro Techniques; Liver; Mitochondria; Rats; Thymine; Ultracentrifugation | 1966 |
Studies on the biochemical mode of action of a cytotoxic methylhydrazine derivative, N-isopropyl-alpha-(2-methylhydrazino)-p-toluamide.
Topics: Adenine; Amines; Animals; Antineoplastic Agents; Carbon Isotopes; DNA; Formates; Guanine; Hydrazines; Imidazoles; Leucine; Lymphoma; Male; Mice; Neoplasms, Experimental; Nucleosides; Nucleotides; Orotic Acid; Protein Biosynthesis; Purines; RNA; Thymidine; Thymidine Kinase; Tritium | 1966 |
The decrepitude of the rat brain with special reference to changes in nucleic acid.
Topics: Adenine; Aging; Animals; Brain Chemistry; Brain Stem; Cerebellum; Chromatography; Cytosine; Diencephalon; DNA; Guanine; Rats; RNA; Thymine; Uracil | 1966 |
Rapid column chromatography of purine and pyrimidine bases on 'Ectaola' cellulose at room temperature and elevated pressure.
Topics: Adenine; Cellulose; Chromatography, Ion Exchange; Cytosine; DNA; Formates; Guanine; Hot Temperature; Pressure; RNA; Thymine; Uracil | 1966 |
Rapidly labeled HeLa cell nuclear RNA. II. Base composition and cellular localization of a heterogeneous RNA fraction.
Topics: Adenine; Cell Nucleus; Centrifugation, Density Gradient; Culture Techniques; Cytosine; Guanine; HeLa Cells; RNA; Tritium; Uracil; Uridine | 1966 |
Size distribution and stability of DNA-like RNA synthesized during development of anucleolate embryos of Xenopus laevis.
Topics: Adenine; Animals; Anura; Carbon Dioxide; Carbon Isotopes; Cell Nucleolus; Centrifugation, Density Gradient; Cytosine; DNA; Embryo, Nonmammalian; Guanine; In Vitro Techniques; RNA; Uracil; Uridine | 1966 |
Codon--anticodon pairing: the wobble hypothesis.
Topics: Adenine; Cytosine; Genetic Code; Guanine; Molecular Biology; Nucleosides; Uracil | 1966 |
Ribonucleic acids of the endoplasmic reticulum of animal cells.
Topics: Adenine; Animals; Centrifugation, Density Gradient; Chromatography; Cytosine; Endoplasmic Reticulum; Female; Guanine; Liver; Liver Glycogen; Male; Membranes; Microsomes; Rats; Ribosomes; RNA; Uracil | 1966 |
Giant-size rapidly labeled nuclear ribonucleic acid and cytoplasmic messenger ribonucleic acid in immature duck erythrocytes.
Topics: Adenine; Anemia; Animals; Carbon Isotopes; Cell Nucleus; Chromatography, Ion Exchange; Cytosine; Dactinomycin; Erythrocytes; Guanine; In Vitro Techniques; Phenylhydrazines; Poultry; Ribosomes; RNA; RNA, Messenger; Thymidine; Tritium; Uracil; Uridine | 1966 |
Composition and content of RNA in neurons of rat hippocampus at different ages.
Topics: Adenine; Aging; Animals; Animals, Newborn; Chemical Phenomena; Chemistry; Cytosine; Electrophoresis; Guanine; Hippocampus; Rats; RNA; Uracil | 1966 |
On the exclusivity of hydrogen-bonded pairing between the Watson-Crick complementary bases.
Topics: Adenine; Chemical Phenomena; Chemistry; Cytosine; Guanine; Nucleic Acids; Thymine | 1966 |
[Chemical and physicochemical study of the constituents of ribosomal RNA of yeast].
Topics: Adenine; Centrifugation, Density Gradient; Cytosine; Guanine; Molecular Weight; Phenols; Polyvinyls; Ribosomes; RNA; Saccharomyces; Solubility; Sulfates; Surface-Active Agents; Temperature; Uracil; Urea | 1966 |
Effect of adenine on the photodynamic inactivation of yeast alcohol dehydrogenase in the presence of riboflavin.
Topics: Adenine; Adenine Nucleotides; Alcohol Oxidoreductases; Cytosine; Guanine; Light; Riboflavin; Thymine; Uracil; Yeasts | 1966 |
A genetic stimulation with production of adenic-uracil rich RNA in neurons and glia in learning. The question of transfer of RNA from glia to neurons.
Topics: Adenine; Animals; Behavior, Animal; Cell Nucleus; Cytosine; DNA; Guanine; Learning; Nerve Tissue; Neuroglia; Neurons; Rats; RNA; Stimulation, Chemical; Uracil | 1966 |
[The photodynamic effect of thiopyronin on nucleic acids].
Topics: Adenine; DNA; Guanine; Indicators and Reagents; Light; Radiation Effects; RNA; Uracil | 1966 |
[Comparison of the properties of DNA, obtained from mitochondria and from nuclei of liver cells].
Topics: Adenine; Animals; Cell Nucleus; Chemical Phenomena; Chemistry; Chromatography; Cytosine; Deoxyribonucleases; DNA; Guanine; Liver; Mitochondria, Liver; Rats; Thymine; Ultracentrifugation | 1966 |
[On the role of xanthine in riboflavine biosynthesis by the yeast Candida guilliermondii].
Topics: Adenine; Candida; Guanine; Nucleotides; Purines; Riboflavin; Uric Acid; Xanthines | 1966 |
Determination of DNA base composition via depurination.
Topics: Adenine; Animals; Brain Chemistry; Cattle; Dialysis; DNA; DNA, Bacterial; DNA, Viral; Guanine; Male; Spectrum Analysis; Spermatozoa; Thymus Gland | 1966 |
Use of low concentrations of actinomycin D in the study of RNA synthesis in Ehrlich ascites cells.
Topics: Adenine; Animals; Carcinoma, Ehrlich Tumor; Cytosine; Dactinomycin; DNA, Neoplasm; Guanine; In Vitro Techniques; RNA, Neoplasm; Spectrophotometry; Uracil | 1966 |
Proof that sequences of A,C,G, and T can be assembled to produce chains of ultimate length avoiding repetitions everywhere.
Topics: Adenine; Chemical Phenomena; Chemistry; Cytosine; Guanine; Mathematics; Polynucleotides; Thymine | 1966 |
Enzyme defect associated with a sex-linked human neurological disorder and excessive purine synthesis.
Topics: Adenine; Adenine Nucleotides; Adolescent; Adult; Aggression; Athetosis; Azathioprine; Cerebral Palsy; Child, Preschool; Chorea; Female; Glucosyltransferases; Guanine; Guanine Nucleotides; Humans; Hypoxanthines; Intellectual Disability; Male; Middle Aged; Purine-Pyrimidine Metabolism, Inborn Errors; Self Mutilation | 1967 |
Azure mutants: a type of host-dependent mutant of the bacteriophage f2.
Topics: Adenine; Coliphages; Genetic Code; Guanine; Hot Temperature; Molecular Biology; Mutation; Nucleotidyltransferases; RNA, Viral; Uracil | 1967 |
Evidence suggesting a non-random character to nucleotide replacements in naturally occurring mutations.
Topics: Adenine; Amino Acid Sequence; Cytochromes; Cytosine; Genetic Code; Guanine; Hemoglobins, Abnormal; Humans; In Vitro Techniques; Molecular Biology; Mutation; Polynucleotides; Uracil | 1967 |
UGA: a third nonsense triplet in the genetic code.
Topics: Adenine; Chemical Phenomena; Chemistry; Coliphages; DNA; Genetic Code; Guanine; Hydroxylamines; Mutation; RNA, Messenger; Tryptophan; Uracil | 1967 |
Dynamical basis of the helical structure of DNA.
Topics: Adenine; Chemical Phenomena; Chemistry, Physical; Cytosine; DNA; Guanine; Models, Theoretical; Thymine | 1967 |
The interaction of aflatoxins with purines and purine nucleosides.
Topics: Adenine; Aflatoxins; Amines; Animals; Cattle; Chemical Phenomena; Chemistry; Chromatography, Gel; DNA; Guanine; Nucleosides; Purines; Spectrophotometry; Temperature; Thymidine; Thymus Gland | 1967 |
Indications of an evolutionary pathway in the amino acid code.
Topics: Adenine; Amino Acids; Biological Evolution; Clostridium; Cytosine; Ferredoxins; Genetic Code; Guanine; Molecular Biology; Protein Biosynthesis; RNA, Transfer; Uracil | 1967 |
Studies of 6-N-hydroxylamino-9-beta-D-ribofuranosylpurine in mouse leukemia.
Topics: Adenine; Animals; Body Weight; Cytarabine; Drug Antagonism; Drug Synergism; Fluorouracil; Guanine; Leukemia; Leukemia L1210; Mercaptopurine; Methotrexate; Mice; Nucleosides; Phosphotransferases; Purines; Vincristine | 1967 |
RNA synthesis in fetal rat liver.
Topics: Adenine; Animals; Animals, Newborn; Cytosine; Female; Fetus; Guanine; In Vitro Techniques; Liver; Phenols; Phosphorus Isotopes; Rats; RNA; Sodium Chloride; Surface-Active Agents; Uracil | 1967 |
Separation and chain-length determination of polynucleotides by gel filtration.
Topics: Adenine; Chromatography, Gel; Cytosine; Guanine; Hydrogen-Ion Concentration; Molecular Weight; Polynucleotides; Thymine; Uracil | 1967 |
Phosphoribosylamidotransferase: regulation of activity in virus-induced murine leukemia by purine nucleotides.
Topics: Adenine; Adenine Nucleotides; Animals; Feedback; Friend murine leukemia virus; Glucosyltransferases; Guanine; Guanine Nucleotides; Leukemia, Experimental; Mice; Spleen | 1967 |
Use of alkali in a rapid procedure for the isolation of partly-degraded deoxyribonucleic acid: investigation of the method introduced by W. Jones.
Topics: Adenine; Alkalies; Cytosine; DNA; Guanine; Uracil | 1967 |
Mass spectra of nucleic acid derivatives. II. Guanine, adenine, and related compounds.
Topics: Adenine; Alkylation; Cytosine; Guanine; Hypoxanthines; Nucleic Acids; Purines; Spectrum Analysis | 1967 |
Hypochromism accompanying purine-pyrimidine association interactions.
Topics: Adenine; Cytosine; DNA; Guanine; Nucleosides; Purines; Pyrimidines; Spectrum Analysis; Ultraviolet Rays; Uracil | 1967 |
Study of the hydrogen bonding in the adenine-thymine, adenine-cytosine, and guanine-thymine base pairs.
Topics: Adenine; Chemical Phenomena; Chemistry, Physical; Cytosine; Guanine; Hydrogen; Nucleotides; Protons; Thymine | 1967 |
Effect of functional group substituents on the paper chromatography of purines and pyrimidines.
Topics: Adenine; Caffeine; Chemical Phenomena; Chemistry; Chromatography, Paper; Cytosine; Guanine; Hydrogen-Ion Concentration; Nitriles; Purines; Pyrimidines; Theobromine; Theophylline; Thymine; Uracil; Water; Xanthines | 1967 |
DNA-associated RNA from sarcoma 180 cells.
Topics: Adenine; Animals; Cytosine; Dactinomycin; DNA, Neoplasm; Guanine; Kinetics; Mice; Nucleotidyltransferases; Pancreas; Phosphorus Isotopes; Ribonucleases; RNA, Neoplasm; Sarcoma 180; Uracil | 1967 |
Studies of the ribosomal ribonucleic acid from mesophilic and thermophilic bacteria.
Topics: Adenine; Bacillus; Cytosine; Guanine; Hot Temperature; Nucleic Acid Denaturation; Nucleotides; Ribonucleases; Ribosomes; RNA, Bacterial; Uracil | 1967 |
Metabolically stable and metabolically labile DNA-like RNA.
Topics: Adenine; Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cell Nucleus; Cytosine; DNA; DNA, Neoplasm; Guanine; In Vitro Techniques; Liver; Mice; Orotic Acid; RNA; RNA, Neoplasm; Ultracentrifugation; Uracil | 1967 |
Interaction between adenine, guanine and thymine in deoxyoligonucleotides: a proton magnetic resonance study.
Topics: Adenine; Guanine; Magnetic Resonance Spectroscopy; Nucleotides; Protons; Thymine | 1967 |
Xanthine phosphoribosyltransferase in man: relationship to hypoxanthine-guanine phosphoribosyltransferase.
Topics: Adenine; Catalysis; Erythrocytes; Glucosyltransferases; Guanine; Humans; Hypoxanthines; Protein Denaturation; Xanthines | 1967 |
Elimination of ribosomes during meiotic prophase.
Topics: Adenine; Guanine; Meiosis; Microscopy, Electron; Plant Cells; Ribosomes; RNA | 1967 |
Hydroxyapatite fractionation procedures in the study of the mammalian genome.
Topics: Adenine; Animals; Binding Sites; Chromatography; Culture Techniques; Cytosine; DNA; Guanine; Hydroxyapatites; Methods; Mice; Nucleic Acid Denaturation; Phosphorus Isotopes; Rats; Temperature; Thymine | 1967 |
Rapid separation of thymine dimer and pyrimidines on ion-exchange paper.
Topics: Adenine; Chromatography, Paper; Cytosine; Guanine; Ion Exchange Resins; Nucleosides; Nucleotides; Pyrimidines; Thymidine; Thymine; Uracil; Uridine | 1967 |
Synthesis of ribosomal RNA during sea-urchin development.
Topics: Adenine; Animals; Cytosine; Echinodermata; Female; Guanine; Ovum; Phosphorus Isotopes; Ribosomes; RNA; Sucrose; Tritium; Ultracentrifugation; Uracil; Uridine | 1967 |
Physiological investigations on heterosis in chickens. IV. Nucleotides of desoxyribonucleic acid in erythrocytes.
Topics: Adenine; Animals; Chickens; Cytosine; DNA; Guanine; Hybridization, Genetic; Thymine | 1967 |
Ribonucleic acid synthesis during morphogenesis in Myxococcus xanthus.
Topics: Adenine; Bacteria; Carbon Isotopes; Centrifugation, Density Gradient; Cytosine; Glycerol; Guanine; Ribosomes; RNA, Bacterial; Tritium; Uracil; Uridine | 1967 |
Nucleoside synthesis under potentially prebiotic conditions.
Topics: Adenine; Cytosine; Guanine; Nucleosides; Pentoses | 1967 |
[The effects of carcinogens and mutagens on nucleic acids. 3. Heat denaturation of hydroxylamine treated DNA].
Topics: Adenine; Animals; Cytosine; DNA; Guanine; Hydroxylamines; In Vitro Techniques; Mutagens; Nucleic Acid Denaturation; Rats; Spectrophotometry; Thymine | 1967 |
Metabolism of serine and glycine in baker's yeast.
Topics: Acetaldehyde; Acetates; Adenine; Carbon Isotopes; Citric Acid Cycle; Formates; Glucose; Glycine; Glycolates; Glyoxylates; Guanine; Histidine; Kinetics; Oxidation-Reduction; Pyruvates; Saccharomyces; Serine; Stimulation, Chemical | 1967 |
The effect of 4-aminopyrazolo(3,4-d)pyrimidine and guanine on Ehrlich ascites cells in culture.
Topics: Adenine; Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Culture Techniques; DNA, Neoplasm; Guanine; Leucine; Mice; Mitosis; Neoplasm Proteins; Pyrazoles; Pyrimidines; RNA, Neoplasm; Thymidine; Uridine | 1967 |
Theoretical study on the alkylation and protonation of the nucleic acid bases.
Topics: Adenine; Alkylation; Carcinogens; Chemical Phenomena; Chemistry; Cytosine; Guanine; Methylation; Mutagens; Nucleic Acids; Protons; Purines; Pyrimidines; Thermodynamics; Thymine; Uracil | 1984 |
Physiological roles of glutamine synthetases I and II in ammonium assimilation in Rhizobium sp. 32H1.
Topics: Adenine; Enzyme Repression; Glutamate-Ammonia Ligase; Guanine; Hydrogen-Ion Concentration; Mutation; Quaternary Ammonium Compounds; Rhizobium | 1980 |
[Age dependency of normal and modified nucleobases in urine in correlation to growth velocity (author's transl)].
Topics: Adenine; Adolescent; Age Factors; Base Sequence; Child; Child, Preschool; Creatinine; Cytosine; Female; Growth; Guanine; Humans; Infant; Male; Mathematics; Nucleosides; Puberty; Reference Values; Thymine; Uracil | 1981 |
Dual control of the gua operon of Escherichia coli K12 by adenine and guanine nucleotides.
Topics: Adenine; Adenine Nucleotides; Aminoimidazole Carboxamide; Carbon-Nitrogen Ligases; Escherichia coli; Gene Expression Regulation; Genes; Guanine; Guanine Nucleotides; IMP Dehydrogenase; Ligases; Mutation; Operon; Purines; Ribonucleotides | 1981 |
Effects of purine amino groups on the development of Drosophila.
Topics: 2-Aminopurine; Adenine; Animals; Charcoal; Drosophila melanogaster; Guanine; Larva; Purines | 1984 |
Purine metabolism in mesophyll protoplasts of tobacco (Nicotiana tabacum) leaves.
Topics: Adenine; Adenosine; Guanine; Hypoxanthines; Nicotiana; Plants; Plants, Toxic; Protoplasts; Purines; RNA | 1980 |
Preservation of red blood cells with purines and nucleosides. II. Uptake and utilization of purines and nucleosides by stored red blood cells.
Topics: Adenine; Blood Preservation; Erythrocytes; Guanine; Guanosine; Humans; Hypoxanthines; Inosine; Nucleosides; Purines; Temperature | 1980 |
Purine metabolism in Trypanosoma cruzi.
Topics: Adenine; Animals; DNA; Guanine; Hypoxanthines; Purine Nucleosides; Purine Nucleotides; Purines; RNA; Trypanosoma cruzi; Xanthines | 1981 |
Are there structural analogies between amino acids and nucleic acids?
Topics: Adenine; Amino Acids; Chemical Phenomena; Chemistry; Codon; Cytosine; DNA; Genetic Code; Guanine; Models, Molecular; Molecular Conformation; Nucleic Acid Conformation; RNA; Thymine | 1981 |
Determination of parameters of excited states of DNA and RNA bases by laser UV photolysis.
Topics: Adenine; Cytosine; DNA; Guanine; Lasers; Photolysis; RNA; Thymine; Ultraviolet Rays; Uracil | 1982 |
Characterization of purine nucleotide metabolism in primary rat muscle cultures.
Topics: Adenine; Animals; Cells, Cultured; Embryo, Mammalian; Formates; Guanine; Hypoxanthines; Kinetics; Muscles; Phosphates; Phosphoribosyl Pyrophosphate; Purine Nucleotides; Rats | 1982 |
[Excretion of normal and modified RNA catabolites and creatinine in the urine as a function of nutrition in children].
Topics: Adenine; Analysis of Variance; Child; Creatinine; Dietary Proteins; Female; Guanine; Humans; Male; Nucleosides; Nutritional Physiological Phenomena; Pseudouridine; RNA; Uridine | 1983 |
Regulation of de novo purine synthesis in human bone marrow mononuclear cells by hypoxanthine.
Topics: Adenine; Bone Marrow; Bone Marrow Cells; DNA; Guanine; Humans; Hypoxanthine; Hypoxanthines; Leukemia, Myeloid, Acute; Leukocytes; Purines; RNA; Thymine | 1983 |
Cytofluorometric DNA base determination for the investigation of heterochromatin and heterochromatin amplification.
Topics: Adenine; Base Composition; Chromatin; Chromomycin A3; Chromosome Banding; Cytosine; DNA; Euchromatin; Guanine; Heterochromatin; Indoles; Plants; Spectrometry, Fluorescence; Staining and Labeling; Thymine | 1983 |
Studies on the quality of pancreatic preparations: enzyme content, prospective bioavailability, bile acid pattern, and contamination with purines.
Topics: Adenine; Amylases; Bile Acids and Salts; Biological Availability; Guanine; Hypoxanthines; Lipase; Pancreatic Extracts; Peptide Hydrolases; Purines | 1983 |
The effect of formycin B on mRNA translation and uptake of purine precursors in Leishmania mexicana.
Topics: Adenine; Animals; Antibiotics, Antineoplastic; Cells, Cultured; Chromatography, High Pressure Liquid; DNA; Formycins; Guanine; Hypoxanthine Phosphoribosyltransferase; Leishmania; Protein Biosynthesis; Protein Precursors; Purines; RNA; RNA, Messenger | 1984 |
Phosphate-guanosine interactions. A model for the involvement of guanine derivatives in autocatalytic reactions of ribonucleic acids.
Topics: Adenine; Chemical Phenomena; Chemistry; Deoxyguanosine; Guanine; Guanosine; Hydrogen Bonding; Kinetics; Magnetic Resonance Spectroscopy; Mathematics; Models, Chemical; Phosphates; RNA; Uridine | 1984 |
Azathioprine and 6-mercaptopurine (6-MP) suppress the human mixed lymphocyte reaction (MLR) by different mechanisms.
Topics: Adenine; Adenosine; Aminoimidazole Carboxamide; Azathioprine; DNA; Guanine; Humans; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Lymphocyte Culture Test, Mixed; Lymphocytes; Mercaptopurine; Xanthine; Xanthines | 1984 |
Identification of a phi X174 coded protein involved in the inhibition of beta-galactosidase synthesis in Escherichia coli.
Topics: Adenine; Bacteriophage phi X 174; beta-Galactosidase; Cyclic AMP; DNA Replication; DNA, Single-Stranded; Escherichia coli; Galactosidases; Guanine; Kinetics; Mutation; Species Specificity; Viral Proteins; Virus Replication | 1980 |
Enzymatic excision of 3-methyladenine and 7-methylguanine by a rat liver nuclear fraction.
Topics: Adenine; Animals; Cell Nucleus; Chromatography, Affinity; DNA Glycosylases; Endonucleases; Guanine; Kinetics; Liver; Molecular Weight; N-Glycosyl Hydrolases; Rats; Substrate Specificity | 1981 |
Comparative effect of S-adenosyl-homocysteine (SAH) and Sinefungin on tRNA-base methylation in whole cells and in vitro.
Topics: Adenine; Adenosine; Animals; Antifungal Agents; Avian Sarcoma Viruses; Cell Transformation, Viral; Escherichia coli; Guanine; Homocysteine; Methylation; RNA, Transfer; S-Adenosylhomocysteine | 1981 |
Inhibition of rotaviruses by selected antiviral substances: mechanisms of viral inhibition and in vivo activity.
Topics: Adenine; Animals; Antiviral Agents; Guanine; Mice; Mice, Inbred Strains; Peptide Biosynthesis; Reoviridae; Reoviridae Infections; Ribavirin; RNA, Viral; Rotavirus | 1982 |
Purine metabolism in Trichomonas vaginalis.
Topics: Adenine; Adenine Nucleotides; Adenosine Monophosphate; Animals; Guanine; Guanine Nucleotides; Guanosine; Nucleoside-Phosphate Kinase; Purine-Nucleoside Phosphorylase; Purines; Trichomonas vaginalis | 1982 |
Binding of nickel (II) to 5'-nucleoside monophosphates and related compounds.
Topics: Adenine; Adenosine Monophosphate; Guanine; Guanosine Monophosphate; Hydrogen-Ion Concentration; Hypoxanthines; Inosine Monophosphate; Nickel; Nucleosides; Nucleotides; Spectrophotometry, Ultraviolet | 1982 |
Kinetics for exchange of imino protons in the d(C-G-C-G-A-A-T-T-C-G-C-G) double helix and in two similar helices that contain a G . T base pair, d(C-G-T-G-A-A-T-T-C-G-C-G), and an extra adenine, d(C-G-C-A-G-A-A-T-T-C-G-C-G).
Topics: Adenine; Guanine; Kinetics; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Oligonucleotides; Protons; Thymidine | 1982 |
Caffeine inhibition of aflatoxin production: mode of action.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Aflatoxins; Aspergillus; Caffeine; Cell Nucleus; Cytoplasm; Guanine; Structure-Activity Relationship; Theophylline; Trace Elements | 1983 |
[Molecular nature of direct gene mutations induced by gamma and ultraviolet irradiation in Saccharomyces cerevisiae yeasts].
Topics: Adenine; Base Sequence; Cytosine; Gamma Rays; Genes; Guanine; Mutation; Saccharomyces cerevisiae; Thymine; Ultraviolet Rays | 1983 |
Evidence that nitroarene metabolites form mutagenic adducts with DNA-adenine as well as with DNA-guanine.
Topics: Adenine; DNA; Fluorenes; Guanine; Mutagenicity Tests; Mutagens; Mutation; Naphthalenes; Nitro Compounds; Polycyclic Compounds; Pyrenes; Salmonella typhimurium; Structure-Activity Relationship | 1983 |
A new theoretical index of biochemical reactivity combining steric and electrostatic factors. An application to yeast tRNAPhe.
Topics: Adenine; Binding Sites; Cations; Chemical Phenomena; Chemistry; Chemistry, Physical; Cytosine; Electrochemistry; Guanine; Models, Biological; Nucleic Acid Conformation; Phosphates; RNA, Fungal; RNA, Transfer, Amino Acyl; Saccharomyces cerevisiae; Uracil | 1984 |
Evidence that binding of 7,12-dimethylbenz(a)anthracene to DNA in mouse embryo cell cultures results in extensive substitution of both adenine and guanine residues.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenine; Animals; Benz(a)Anthracenes; Carbon Radioisotopes; Cells, Cultured; DNA; Embryo, Mammalian; Female; Guanine; Kinetics; Mice; Pregnancy; Tritium | 1983 |
Immunochemical evidence for the presence of 5mC, 6mA and 7mG in human, Drosophila and mealybug DNA.
Topics: 5-Methylcytosine; Adenine; Animals; Antibodies; Chemical Phenomena; Chemistry; Cytosine; DNA; Drosophila melanogaster; Female; Guanine; Humans; Immunochemistry; Insecta; Male; Placenta; Rats; Species Specificity; Spermatozoa | 1983 |
[The genetic code and cyclic codes].
Topics: Adenine; Cytosine; Genetic Code; Guanine; Mathematics; Models, Genetic; Uracil | 1983 |
Specificity and control of uptake of purines and other compounds in Bacillus subtilis.
Topics: Adenine; Adenosine; Aminoisobutyric Acids; Bacillus subtilis; Biological Transport; Guanine; Guanosine; Guanosine Triphosphate; Hypoxanthine; Hypoxanthines; Inosine; Kinetics; Methylglucosides; Methylglycosides; Purines; Spores, Bacterial; Uracil | 1983 |
Urinary excretion of methylated purines and 1-methyl-nicotinamide following administration of methylating carcinogens.
Topics: 1,2-Dimethylhydrazine; Adenine; Alkylating Agents; Animals; Carcinogens; Dimethylhydrazines; Dimethylnitrosamine; Guanine; Male; Methyl Methanesulfonate; Methylation; Methylnitronitrosoguanidine; Niacinamide; Rats | 1980 |
Purine metabolism and urate biosynthesis in isolated chicken hepatocytes.
Topics: Adenine; Animals; Chickens; Glutamine; Guanine; In Vitro Techniques; Kinetics; Liver; Male; Phosphates; Purines; Uric Acid | 1984 |
Bilirubin incorporation into spiroplasma membranes and methylation of spiroplasmal DNA.
Topics: 5-Methylcytosine; Adenine; Base Composition; Bilirubin; Cell Membrane; Cytosine; DNA, Bacterial; Guanine; Methylation; Spiroplasma | 1984 |
Properties of the O6-alkylguanine-DNA repair system of mammalian cells.
Topics: Adenine; Animals; Diethylnitrosamine; Dimethylnitrosamine; DNA Repair; Guanine; In Vitro Techniques; Liver; Nitroso Compounds; Rats | 1984 |
Purine metabolism in rat macrophages.
Topics: Adenine; Adenine Nucleotides; Animals; Guanine; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Macrophages; Phosphorylation; Purines; Rats; Xanthine Oxidase | 1984 |
DNA alkylation and tumor induction in regenerating rat liver after cell cycle-related continuous N-nitrosodimethylamine infusion.
Topics: Adenine; Alkylation; Animals; Carbon Radioisotopes; Cell Cycle; Dimethylnitrosamine; DNA; Guanine; In Vitro Techniques; Liver; Liver Regeneration; Male; Rats; Rats, Inbred Strains | 1983 |
Detection of a guanine X adenine base pair in a decadeoxyribonucleotide by proton magnetic resonance spectroscopy.
Topics: Adenine; Base Composition; Guanine; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Oligonucleotides | 1983 |
Identification of guanine and adenine adducts in DNA alkylated by dibromodulcitol in vitro and in vivo.
Topics: Adenine; Alkylation; Animals; Cattle; Chromatography, Gel; DNA; Guanine; Mitolactol; Rats; Sarcoma, Yoshida | 1983 |
The consequences of base-pair substitution mutations in AT- and GC-rich bacteria.
Topics: Adenine; Amino Acids; Animals; Bacterial Proteins; Base Composition; Codon; Cytosine; DNA, Bacterial; Genetic Code; Guanine; Mutation; Thymine | 1983 |
Purine nucleotide metabolism in primary rat skeletal muscle cultures.
Topics: Adenine; Animals; Carbon Radioisotopes; Cells, Cultured; Embryo, Mammalian; Formates; Guanine; Hypoxanthine; Hypoxanthines; Muscles; Purine Nucleotides; Rats | 1984 |
Interaction among the distinct effects of adenine and guanine depletion in mouse lymphoma cells.
Topics: Adenine; Adenosine; Alanine; Animals; Antimetabolites, Antineoplastic; Cell Division; DNA Replication; Guanine; Kinetics; Lymphoma; Methylthioinosine; Mice; Mycophenolic Acid | 1984 |
AT base pairs are less stable than GC base pairs in Z-DNA: the crystal structure of d(m5CGTAm5CG).
Topics: Adenine; Base Composition; Cytosine; DNA; Drug Stability; Guanine; Models, Molecular; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Oligonucleotides; Thymine | 1984 |
Genome complexity of methanogenic bacteria.
Topics: Adenine; Base Composition; Base Sequence; Cytosine; DNA, Bacterial; Euryarchaeota; Genes, Bacterial; Guanine; Nucleic Acid Denaturation; Nucleic Acid Renaturation; Species Specificity; Thymine | 1984 |
[Biosynthesis of purine nucleotides in the rat muscle after castration].
Topics: Adenine; Animals; Castration; Formates; Guanine; Male; Muscles; Purine Nucleotides; Rats; Rats, Inbred Strains | 1984 |
[Effect of castration on purine biosynthesis in the rat liver and kidney].
Topics: Adenine; Animals; Castration; Formates; Guanine; Kidney; Liver; Male; Purine Nucleotides; Rats; Rats, Inbred Strains | 1984 |
Leishmania mexicana: purine metabolism in promastigotes, axenic amastigotes, and amastigotes derived from Vero cells.
Topics: Adenine; Adenine Nucleotides; Animals; Cell Line; Chlorocebus aethiops; Guanine; Guanine Nucleotides; Hypoxanthine; Hypoxanthines; Leishmania; Purine Nucleotides | 1984 |
Purine metabolism in Neisseria gonorrhoeae: the requirement for hypoxanthine.
Topics: Adenine; Culture Media; Glycine; Guanine; Hypoxanthines; Mutation; Neisseria gonorrhoeae; Phenotype; Purines; Transformation, Bacterial | 1980 |
Utilization of 2,6-diaminopurine by Salmonella typhimurium.
Topics: 2-Aminopurine; Adenine; Adenosine Deaminase; Guanine; Mutation; Purine-Nucleoside Phosphorylase; Purines; Salmonella typhimurium | 1980 |
Repair of O6-methylguanine in rat liver DNA is enhanced by pretreatment with single or multiple doses of aflatoxin B1.
Topics: Adenine; Aflatoxin B1; Aflatoxins; Animals; Dimethylnitrosamine; DNA Repair; Guanine; Liver; Male; Rats; Stimulation, Chemical | 1981 |
The electrostatic field of the component units of DNA and its relationship to hydration.
Topics: Adenine; Cytosine; DNA; Electrochemistry; Guanine; Macromolecular Substances; Nucleic Acid Conformation; Thymine | 1983 |
Use of high performance liquid chromatography to study absorption and metabolism of purines by rat jejunum in vitro.
Topics: Absorption; Adenine; Animals; Chromatography, High Pressure Liquid; Guanine; Hypoxanthines; Jejunum; Male; Nucleic Acids; Purines; Rats; Rats, Inbred Strains; Uric Acid; Xanthines | 1983 |
O6-methylguanine, but not N7-methylguanine or N3-methyladenine, induces gene mutations, sister-chromatid exchanges and chromosomal aberrations in Chinese hamster cells.
Topics: Adenine; Animals; Cells, Cultured; Chromosome Aberrations; Cricetinae; Crossing Over, Genetic; Dose-Response Relationship, Drug; Guanine; Karyotyping; Mutation; Sister Chromatid Exchange | 1983 |
High-resolution NMR studies of A- and G-containing oligonucleotides.
Topics: Adenine; Guanine; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Oligonucleotides; Oligoribonucleotides; Structure-Activity Relationship | 1983 |
O6-Methylguanine removal by competent and incompetent human lymphoblastoid lines from the same male individual.
Topics: Adenine; Cell Division; Cell Line; Chromosome Aberrations; Guanine; Humans; Karyotyping; Lymphocyte Activation; Lymphocytes; Male; Methylnitronitrosoguanidine | 1983 |
Persistence of methylated purines in the DNA of various rat fetal and maternal tissues and carcinogenesis in the offspring following a single transplacental dose of N-methyl-N-nitrosourea.
Topics: Adenine; Animals; Brain; DNA; Female; Fetus; Guanine; Kidney; Liver; Methylation; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Placenta; Pregnancy; Purines; Rats; Time Factors | 1983 |
The electrostatic molecular potential of tRNAPhe. IV. The potentials and steric accessibilities of sites associated with the bases.
Topics: Adenine; Base Sequence; Chemical Phenomena; Chemistry, Physical; Cytosine; Guanine; Phenylalanine; RNA, Transfer; Saccharomyces cerevisiae; Uracil | 1980 |
Enzymatic release of 7-methylguanine from methylated DNA by rodent liver extracts.
Topics: Adenine; Animals; Cattle; Cricetinae; DNA; DNA Glycosylases; Escherichia coli; Guanine; Kinetics; Liver; Methylation; N-Glycosyl Hydrolases; Rats; Thymus Gland | 1981 |
Purine metabolism during continuous erythrocyte culture of human malaria parasites (P. falciparum).
Topics: Adenine; Adenosine; Adenosine Triphosphate; Carbon Radioisotopes; Erythrocytes; Guanine; Humans; Hypoxanthines; Plasmodium falciparum; Purines | 1981 |
Uridine and uracil transport in Escherichia coli and transport-deficient mutants.
Topics: Adenine; Adenosine; Biological Transport; Escherichia coli; Guanine; Hypoxanthines; Inosine; Kinetics; Mutation; Species Specificity; Thymine; Uracil; Uridine | 1981 |
Two DNA glycosylases in Escherichia coli which release primarily 3-methyladenine.
Topics: Adenine; Bacterial Proteins; DNA Glycosylases; Escherichia coli; Guanine; Hot Temperature; Isoelectric Focusing; Kinetics; Molecular Weight; N-Glycosyl Hydrolases; Substrate Specificity | 1982 |
Adenine-guanine base pairing ribosomal RNA.
Topics: Adenine; Base Composition; Base Sequence; Escherichia coli; Guanine; Hydrogen Bonding; Molecular Weight; Nucleic Acid Conformation; RNA, Ribosomal | 1982 |
Cellular defense mechanisms against alkylation of DNA.
Topics: Adenine; Alkylation; DNA Glycosylases; DNA Repair; Escherichia coli; Guanine; Methyltransferases; Mutation; N-Glycosyl Hydrolases; S-Adenosylmethionine | 1982 |
Interconversion and uptake of nucleotides, nucleosides, and purine bases by the marine bacterium MB22.
Topics: Adenine; Bacteria; Biological Transport, Active; Cell Membrane; Guanine; Hypoxanthines; Kinetics; Purine Nucleosides; Purine Nucleotides; Purines; Seawater; Water Microbiology | 1982 |
[Uric acid load test. Proof of its value using the sequential probability ratio test].
Topics: Adenine; Adult; Female; Gout; Guanine; Humans; Male; Probability; Uric Acid | 1982 |
Nonenzymatic methylation of DNA by S-adenosylmethionine in vitro.
Topics: Adenine; Animals; Cattle; Chromatography, High Pressure Liquid; DNA; DNA Repair; Guanine; In Vitro Techniques; Methylation; S-Adenosylmethionine; Scintillation Counting; Spectrophotometry, Ultraviolet | 1982 |
Comparison of purine and pyrimidine metabolism in G1 and S phases of HeLa and Chinese hamster ovary cells.
Topics: Adenine; Animals; Cricetinae; Cricetulus; Cytidine; Female; Guanine; HeLa Cells; Humans; Interphase; Ovary; Purine Nucleotides; Pyrenes; Pyrimidine Nucleotides; Pyrimidines; Thymidine | 1982 |
Dose- and cell cycle-dependent O6-methylguanine elimination from DNA in regenerating rat liver after [14C]dimethylnitrosamine injection.
Topics: Adenine; Animals; Dimethylnitrosamine; DNA; DNA Repair; Dose-Response Relationship, Drug; Guanine; Interphase; Liver; Liver Regeneration; Male; Rats | 1982 |
Partial purification and characterization of 3-methyladenine-DNA glycosylase from human placenta.
Topics: Adenine; Chromatography, High Pressure Liquid; DNA Glycosylases; Female; Guanine; Humans; N-Glycosyl Hydrolases; Placenta; Pregnancy; Substrate Specificity | 1982 |
N-Sulfomethylation of guanine, adenine and cytosine with formaldehyde-bisulfite. A selective modification of guanine in DNA.
Topics: Adenine; Cytosine; DNA; Formaldehyde; Guanine; Methylation; Molecular Conformation; Nucleosides; Nucleotides; Structure-Activity Relationship; Sulfites | 1982 |
Interactions of nucleic-acid base-pairs with acidic side chains of protein. Crystal structures of adenine: 1-(2-carboxyethyl)uracil (1:1) complex and 1-methylcytosine: 9-(2-carboxyethyl)guanine (1:1) complex.
Topics: Adenine; Base Composition; Cytosine; Guanine; Hydrogen Bonding; Models, Molecular; Nucleic Acid Conformation; Proteins; Uracil; X-Ray Diffraction | 1982 |
Chemical reactivity of a methyldiazonium ion with nucleophilic centers of DNA bases.
Topics: Adenine; Alkylation; Base Composition; Binding Sites; Diazonium Compounds; DNA; Guanine; Hydrogen Bonding; Quantum Theory | 1980 |
[DNA methylation characteristics of different fetal and maternal body tissues in rats administered 1,2-dimethylhydrazine].
Topics: 1,2-Dimethylhydrazine; Adenine; Animals; Dimethylhydrazines; DNA; Female; Fetus; Guanine; Methylation; Methylhydrazines; Pregnancy; Rats; Tissue Distribution | 1981 |
Physical association modeling of DNA alkylation. Some DNA conformational aspects.
Topics: Adenine; Alkylating Agents; Alkylation; Base Composition; Base Sequence; Cytosine; DNA; Guanine; Models, Molecular; Nucleic Acid Conformation; Thymine | 1981 |
The use of diethylpyrocarbonate for sequencing adenines and guanines in DNA.
Topics: Adenine; Base Sequence; Diethyl Pyrocarbonate; DNA; Formates; Guanine; Hydrogen-Ion Concentration; Methods | 1981 |
Adenine, the precursor of nucleic acids in intestinal cells unable to synthesize purines de novo.
Topics: Adenine; Animals; Epithelium; Guanine; Hepatectomy; Hypoxanthine; Hypoxanthines; Intestinal Mucosa; Male; Purines; Rats; Xanthine; Xanthines | 1981 |
Reaction of trichloromethyl free radicals with deoxyribonucleic acid bases.
Topics: Adenine; Carbon Tetrachloride; Chromatography, Ion Exchange; Cytosine; DNA; Guanine; Thymine | 1981 |
A working hypothesis on the interdependent genesis of nucleotide bases, protein amino acids, and primitive genetic code.
Topics: Adenine; Amino Acids; Biological Evolution; Chemical Phenomena; Chemistry; Codon; Cytosine; Genetic Code; Guanine; Models, Biological; Purines; Pyrimidines; Uracil | 1981 |
[Ratio of natural DNA hydration to the GC content].
Topics: Adenine; Biophysical Phenomena; Biophysics; Cytosine; DNA; Guanine; Molecular Conformation; Polynucleotides; Solutions; Thymine; Water | 1981 |
Nearest-neighbor and next-nearest-neighbor effects in the proton NMR spectra of the oligoribonucleotides ApGpX and CpApX.
Topics: Adenine; Chemical Phenomena; Chemistry, Physical; Cytosine; Guanine; Magnetic Resonance Spectroscopy; Oligonucleotides; Oligoribonucleotides; Protons; Spectrum Analysis; Temperature; Uracil | 1980 |
Chemical reactivity of protonated aziridine with nucleophilic centers of DNA bases.
Topics: Adenine; Ammonia; Aziridines; Azirines; Chemical Phenomena; Chemistry; DNA; Formaldehyde; Guanine; Imines; Molecular Conformation | 1980 |
A direct method for the preparation of 2-hydroxyethoxymethyl derivatives of guanine, adenine, and cytosine.
Topics: Adenine; Antiviral Agents; Cytosine; Drug Stability; Guanine; Methods | 1980 |
In vivo replication of hepatic deoxyribonucleic acid of rats treated with dimethylnitrosamine: presence of dimethylnitrosamine-induced O6-methylguanine, N7-methylguanine, and N3-methyladenine in the replicated hybrid deoxyribonucleic acid.
Topics: Adenine; Animals; Dimethylnitrosamine; DNA Replication; Guanine; Liver; Male; Nucleic Acid Hybridization; Rats | 1980 |
Inability of Chinese hamster ovary cells to excise O6-alkylguanine.
Topics: Adenine; Alkylating Agents; Animals; Cricetinae; Cricetulus; DNA; DNA Repair; Ethylnitrosourea; Female; Guanine; Methylnitrosourea; Ovary; Pyrimidine Dimers; Time Factors | 1980 |
A novel synergistic effect of alanosine and guanine on adenine nucleotide synthesis in mammalian cells. Alanosine as a useful probe for investigating purine nucleotide metabolism.
Topics: Adenine; Adenine Nucleotides; Adenylosuccinate Synthase; Alanine; Animals; Cell Division; Cell Line; Cricetinae; Dose-Response Relationship, Drug; Drug Synergism; Female; Guanine; Humans; Nitrosamines; Ovary; Purine Nucleotides | 1980 |
Metabolism of orally and intravenously administered purines in rats.
Topics: Adenine; Administration, Oral; Animals; Fasting; Guanine; Hypoxanthines; Injections, Intravenous; Intestinal Mucosa; Purines; Rats; Tissue Distribution; Xanthines | 1980 |
Salvage pathway in erythrocytes of patients with psoriasis.
Topics: Adenine; Adenine Nucleotides; Carbon Radioisotopes; Erythrocytes; Guanine; Humans; Hypoxanthines; Psoriasis; Purines | 1980 |
[Accumulation of methylated purines in the liver and large intestine DNA of rats following repeated administrations of 1,2-dimethylhydrazine].
Topics: Adenine; Animals; Dimethylhydrazines; DNA; Guanine; Intestine, Large; Liver; Male; Methylation; Methylhydrazines; Rats | 1980 |
Theoretical analysis of charge-transfer bands of some nucleic acid bases with chloranil.
Topics: Adenine; Chloranil; Cytosine; Electrons; Guanine; Quinones; Thermodynamics | 1980 |
Point mutation of the mitochondrial tRNA(Leu) gene (A 3243 G) in maternally inherited hypertrophic cardiomyopathy, diabetes mellitus, renal failure, and sensorineural deafness.
Topics: Adenine; Adult; Cardiomyopathy, Hypertrophic; Deafness; Diabetes Complications; Diabetes Mellitus; Female; Guanine; Humans; Male; Middle Aged; Pedigree; Point Mutation; Renal Insufficiency; RNA, Transfer, Leu | 1995 |
DNA damage in human respiratory tract epithelial cells: damage by gas phase cigarette smoke apparently involves attack by reactive nitrogen species in addition to oxygen radicals.
Topics: Adenine; Bronchi; Cell Line; DNA; DNA Damage; Epithelium; Guanine; Humans; Hydroxyl Radical; Hypoxanthine; Hypoxanthines; Smoke; Smoking; Xanthine; Xanthines | 1995 |
Structural studies of DNA and RNA containing AG base pairs by NMR.
Topics: Adenine; Base Composition; Base Sequence; DNA; Guanine; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Nucleic Acid Conformation; RNA; RNA, Catalytic | 1993 |
A donor splice mutation (405 + 1 G-->A) in cystic fibrosis associated with exon skipping in epithelial CFTR mRNA.
Topics: Adenine; Adult; Alternative Splicing; Base Sequence; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; DNA Primers; Epithelium; Exons; Female; Guanine; Humans; Introns; Membrane Proteins; Molecular Sequence Data; Point Mutation; Polymerase Chain Reaction; RNA, Messenger | 1993 |
DNA-directed aniline mustards with high selectivity for adenine or guanine bases: mutagenesis in a variety of Salmonella typhimurium strains differing in DNA-repair capability.
Topics: Adenine; Alkylation; Aniline Mustard; DNA Damage; DNA Repair; Guanine; Intercalating Agents; Mutagenesis, Site-Directed; Mutagens; Point Mutation; Salmonella typhimurium; Species Specificity | 1994 |
Formation of sheared G:A base pairs in an RNA duplex modelled after ribozymes, as revealed by NMR.
Topics: Adenine; Base Composition; Base Sequence; DNA; Drug Stability; Guanine; Hot Temperature; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Nucleic Acid Denaturation; Oligodeoxyribonucleotides; Oligoribonucleotides; RNA; RNA, Catalytic; Thermodynamics | 1994 |
The purine 2-amino group as a critical recognition element for binding of small molecules to DNA.
Topics: 2-Aminopurine; Adenine; Anti-Bacterial Agents; Autoradiography; Base Sequence; Dactinomycin; Deoxyribonuclease I; DNA; Echinomycin; Guanine; Inosine; Molecular Sequence Data; Netropsin; Nucleic Acid Conformation; RNA, Transfer, Tyr | 1994 |
Hypermutagenesis of RNA using human immunodeficiency virus type 1 reverse transcriptase and biased dNTP concentrations.
Topics: Adenine; Base Sequence; Cloning, Molecular; Deoxyribonucleotides; DNA Primers; Genes, env; Guanine; HIV Reverse Transcriptase; HIV-1; Kinetics; Molecular Sequence Data; Mutagenesis; Point Mutation; Polymerase Chain Reaction; Recombinant Proteins; RNA-Directed DNA Polymerase; RNA, Viral; Substrate Specificity; Virus Replication | 1994 |
Purine-purine mismatches in RNA helices: evidence for protonated G.A pairs and next-nearest neighbor effects.
Topics: Adenine; Base Composition; Base Sequence; Guanine; Hydrogen-Ion Concentration; Molecular Sequence Data; Nucleic Acid Conformation; Protons; RNA; Thermodynamics | 1995 |
Detection of point mutations by capillary electrophoresis in liquid polymers in temporal thermal gradients.
Topics: Adenine; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Cytosine; DNA; Electrophoresis; Exons; Guanine; Heterozygote; Humans; Membrane Proteins; Point Mutation; Polymerase Chain Reaction; Polymers; Polymorphism, Genetic; Thermodynamics; Thymine | 1994 |
The stability and structure of tandem GA mismatches in RNA depend on closing base pairs.
Topics: Adenine; Base Composition; Base Sequence; Calorimetry; Drug Stability; Guanine; Hydrogen Bonding; Imines; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Nucleic Acid Denaturation; Oligoribonucleotides; Phylogeny; RNA; Structure-Activity Relationship; Thermodynamics | 1994 |
NF1 gene mutations in Japanese with neurofibromatosis 1 (NF1).
Topics: Adenine; Adult; Base Sequence; DNA, Complementary; Exons; Female; Guanine; Humans; Introns; Japan; Molecular Sequence Data; Mutation; Neurofibromatosis 1; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; RNA Splicing; RNA-Directed DNA Polymerase; RNA, Messenger; Sequence Analysis, DNA | 1995 |
Benzenediazonium ion derived from Sudan I forms an 8-(phenylazo)guanine adduct in DNA.
Topics: Adenine; Animals; Carcinogens; Cattle; Chromatography, High Pressure Liquid; Diazonium Compounds; DNA Adducts; Guanine; In Vitro Techniques; Male; Microsomes, Liver; Naphthols; Nucleotides; Rats; Rats, Sprague-Dawley; Spectrophotometry, Ultraviolet; Subcellular Fractions | 1995 |
Insulin sensitivity in patients with NIDDM and the A-to-G mutation at nucleotide 3,243 of the mitochondrial tRNALeu(UUR) gene.
Topics: Adenine; Adult; Blood Glucose; Body Mass Index; C-Peptide; Diabetes Mellitus, Type 2; Family; Female; Glucose Clamp Technique; Glycated Hemoglobin; Guanine; Hearing Loss; Humans; Insulin; Male; Middle Aged; Point Mutation; Polymerase Chain Reaction; Proteinuria; RNA; RNA, Mitochondrial; RNA, Transfer, Leu | 1995 |
The major, N2-Gua adduct of the (+)-anti-benzo[a]pyrene diol epoxide is capable of inducing G-->A and G-->C, in addition to G-->T, mutations.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adenine; Base Sequence; Cytosine; Deoxyribonucleases, Type II Site-Specific; DNA Adducts; Escherichia coli; Genes, Bacterial; Guanine; Molecular Sequence Data; Mutagenesis, Insertional; Mutagens; Oligodeoxyribonucleotides; Plasmids; Point Mutation; Restriction Mapping; Structure-Activity Relationship; Thymine | 1995 |
Induction of kinetochore-containing micronuclei by exogenous O6-methylguanine requires conversion of the methylated base to a nucleotide.
Topics: Adenine; Animals; Cell Line; Cricetinae; Cricetulus; Guanine; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Kinetochores; Methyl Methanesulfonate; Mice; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagens | 1995 |
Decreased cerebral blood perfusion in an NIDDM patient with an A-to-G mutation in the mitochondrial gene; a possible contribution to cognition deficits in diabetes.
Topics: Adenine; Brain; Cerebrovascular Circulation; Cognition Disorders; Diabetes Mellitus, Type 2; DNA, Mitochondrial; Guanine; Humans; Iodine Radioisotopes; Male; Middle Aged; Point Mutation; Tomography, Emission-Computed, Single-Photon | 1995 |
A novel mutation of the adrenocorticotropin receptor (ACTH-R) gene in a family with the syndrome of isolated glucocorticoid deficiency, but no ACTH-R abnormalities in two families with the triple A syndrome.
Topics: Adenine; Adolescent; Adult; Amino Acid Sequence; Base Sequence; Cell Membrane; Cysteine; DNA; DNA Primers; Female; Genes, Recessive; Genetic Carrier Screening; Genetic Diseases, Inborn; Glucocorticoids; Guanine; Homozygote; Humans; Male; Middle Aged; Molecular Sequence Data; Pedigree; Point Mutation; Polymerase Chain Reaction; Protein Structure, Secondary; Receptors, Corticotropin; Syndrome; Tyrosine | 1995 |
Brugia pahangi: effects of melanization on the uptake of nutrients by microfilariae in vitro.
Topics: Adenine; Animals; Arachidonic Acid; Biological Transport; Brugia pahangi; Carbon Radioisotopes; Cats; Culex; Female; Glucose; Glycine; Guanine; Leucine; Linoleic Acid; Linoleic Acids; Melanins; Microscopy, Electron; Radioisotope Dilution Technique; Tritium | 1995 |
Compilation and analysis of Bacillus subtilis sigma A-dependent promoter sequences: evidence for extended contact between RNA polymerase and upstream promoter DNA.
Topics: Adenine; Bacillus subtilis; Base Sequence; Conserved Sequence; DNA-Directed RNA Polymerases; DNA, Bacterial; Guanine; Molecular Sequence Data; Nucleic Acid Conformation; Promoter Regions, Genetic; Repetitive Sequences, Nucleic Acid; Sequence Analysis, DNA; Sigma Factor; Thymine | 1995 |
Segregation of mitochondrial DNAs carrying a pathogenic point mutation (tRNA(leu3243)) in cybrid cells.
Topics: Adenine; Animals; Bone Neoplasms; Cell Fusion; Clone Cells; DNA, Mitochondrial; Genotype; Guanine; Humans; Hybrid Cells; Muscles; Osteosarcoma; Point Mutation; RNA, Transfer, Leu; Tumor Cells, Cultured | 1995 |
Phenotyping of CYP2C19 with enantiospecific HPLC-quantification of R- and S-mephenytoin and comparison with the intron4/exon5 G-->A-splice site mutation.
Topics: Adenine; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Amino Acid Sequence; Arginine; Aryl Hydrocarbon Hydroxylases; Base Sequence; Body Weight; Chromatography, High Pressure Liquid; Cysteine; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme System; DNA Primers; Exons; Female; Genetic Variation; Genotype; Guanine; Humans; Introns; Male; Mephenytoin; Middle Aged; Mixed Function Oxygenases; Molecular Sequence Data; Phenotype; Point Mutation; Polymerase Chain Reaction; Reproducibility of Results; RNA Splicing; Sex Characteristics; Stereoisomerism; Substrate Specificity | 1995 |
A constitutively activating mutation of the luteinizing hormone receptor in familial male precocious puberty.
Topics: Adenine; Amino Acid Sequence; Animals; Base Sequence; Cell Line; Chorionic Gonadotropin; Cyclic AMP; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; DNA Mutational Analysis; DNA Primers; Female; Guanine; Humans; Leydig Cells; Male; Molecular Sequence Data; Mutation; Pedigree; Polymerase Chain Reaction; Puberty, Precocious; Receptors, LH; Recombinant Proteins; Transfection | 1993 |
Transgenic expression of human MGMT protects against azoxymethane-induced aberrant crypt foci and G to A mutations in the K-ras oncogene of mouse colon.
Topics: Adenine; Animals; Azoxymethane; Base Sequence; Codon; Colon; DNA Primers; DNA Repair; Genes, ras; Guanine; Humans; Intestinal Mucosa; Methyltransferases; Mice; Mice, Transgenic; Molecular Sequence Data; Mutation; O(6)-Methylguanine-DNA Methyltransferase | 1995 |
Geometries, charges, dipole moments and interaction energies of normal, tautomeric and novel bases.
Topics: Adenine; Base Composition; Cytosine; DNA; Guanine; Hydrogen Bonding; Isomerism; Mathematics; Models, Genetic; Models, Structural; Models, Theoretical; Thymine | 1994 |
Adherence to the first-AUG rule when a second AUG codon follows closely upon the first.
Topics: Adenine; Animals; Base Sequence; Chloramphenicol O-Acetyltransferase; Codon, Initiator; Consensus Sequence; DNA Primers; Guanine; Models, Genetic; Molecular Sequence Data; Peptide Chain Initiation, Translational; Plasmids; Protein Biosynthesis; Rabbits; Restriction Mapping; Reticulocytes; Ribosomes; RNA, Messenger; Transcription, Genetic; Uracil | 1995 |
Marked differences in the role of O6-alkylguanine in hprt mutagenesis in T-lymphocytes of rats exposed in vivo to ethylmethanesulfonate, N-(2-hydroxyethyl)-N-nitrosourea, or N-ethyl-N-nitrosourea.
Topics: Adenine; Animals; Base Composition; Base Sequence; Carcinogens; DNA Adducts; DNA, Complementary; Drug Resistance; Ethyl Methanesulfonate; Ethylnitrosourea; Guanine; Hypoxanthine Phosphoribosyltransferase; In Vitro Techniques; Male; Molecular Sequence Data; Mutagenesis; Point Mutation; Polymerase Chain Reaction; Rats; Rats, Inbred Lew; T-Lymphocytes; Thioguanine; Thymidine | 1995 |
Transferring the purine 2-amino group from guanines to adenines in DNA changes the sequence-specific binding of antibiotics.
Topics: 2-Aminopurine; Adenine; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Base Sequence; Binding Sites; Dinucleoside Phosphates; DNA; Guanine; Inosine; Intercalating Agents; Ligands; Molecular Sequence Data; Peptides; RNA, Transfer, Tyr | 1995 |
Homozygosity for a novel missense mutation in the prothrombin gene causing a severe bleeding disorder.
Topics: Adenine; Base Composition; Base Sequence; Exons; Female; Guanine; Hemorrhage; Homozygote; Humans; Hypoprothrombinemias; Male; Molecular Sequence Data; Mutation; Pedigree; Polymerase Chain Reaction; Prothrombin | 1994 |
Hydrogen bonding motifs of protein side chains: descriptions of binding of arginine and amide groups.
Topics: Adenine; Amides; Arginine; Asparagine; Glutamine; Guanine; Protein Binding; Protein Conformation; Proteins; Urea | 1995 |
Direct measurement of hydrogen bonding in DNA nucleotide bases by atomic force microscopy.
Topics: Adenine; Base Composition; Cytosine; DNA; Gold; Guanine; Hydrogen Bonding; Microscopy, Atomic Force; Thymine | 1995 |
Erratic G-->A hypermutation within a complete caprine arthritis-encephalitis virus (CAEV) provirus.
Topics: Adenine; Amino Acid Sequence; Animals; Arthritis-Encephalitis Virus, Caprine; Base Sequence; Cloning, Molecular; DNA Primers; Gene Products, env; Gene Products, rev; Genes, pol; Genetic Variation; Genome, Viral; Goats; Guanine; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Protein Sorting Signals; Proviruses | 1995 |
Modification of DNA bases by anthralin and related compounds.
Topics: Adenine; Animals; Anthralin; Cattle; Dermatologic Agents; DNA; DNA Damage; Gas Chromatography-Mass Spectrometry; Guanine; Hydroxylation; Pyrimidines | 1995 |
Alkylation of purine bases with 3,4-epoxy-1-butene, a reactive metabolite of 1,3-butadiene.
Topics: Adenine; Alkylation; Butadienes; Chromatography, High Pressure Liquid; DNA; DNA Adducts; Electrochemistry; Epoxy Compounds; Guanine; Heating; Hydrolysis; Magnetic Resonance Spectroscopy; Mutagens; Purines; Sensitivity and Specificity | 1994 |
Salvage synthesis of purine nucleotides by Helicobacter pylori.
Topics: Adenine; Adenylate Kinase; Deoxyribonucleosides; Deoxyribonucleotides; Guanine; Helicobacter pylori; Magnetic Resonance Spectroscopy; N-Glycosyl Hydrolases; Pentosyltransferases; Phosphorus Isotopes; Purine Nucleotides; Purines; Ribonucleosides | 1994 |
Oxidative modification of DNA bases in rat liver and lung during chemical carcinogenesis and aging.
Topics: 2-Acetylaminofluorene; Adenine; Aging; Animals; Antineoplastic Agents; Disease Models, Animal; DNA Damage; DNA, Neoplasm; Gas Chromatography-Mass Spectrometry; Guanine; Hydrolysis; Liver; Liver Neoplasms, Experimental; Lung; Lung Neoplasms; Male; Methylamines; Nitrates; Oxidation-Reduction; Pyrimidines; Random Allocation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Thymine; Uracil | 1995 |
3-Methyladenine and 7-methylguanine exhibit no preferential removal from the transcribed strand of the dihydrofolate reductase gene in Chinese hamster ovary B11 cells.
Topics: Adenine; Animals; Autoradiography; CHO Cells; Cricetinae; DNA Damage; Guanine; Tetrahydrofolate Dehydrogenase; Transcription, Genetic | 1995 |
Exact vs approximate methods for simulation of 3D NOE-NOE spectra.
Topics: Adenine; Algorithms; Amino Acid Sequence; Computer Simulation; Energy Transfer; Guanine; Magnetic Resonance Spectroscopy; Magnetics; Models, Chemical; Nucleotide Mapping; Oligonucleotides | 1995 |
Differential effect of duocarmycin A and its novel derivative DU-86 on DNA strand breaks in HeLa S3 cells.
Topics: Adenine; Alkalies; Alkylating Agents; Antibiotics, Antineoplastic; Cell Cycle; Cell Division; Cell Survival; Chemistry Techniques, Analytical; DNA; DNA Adducts; DNA Damage; Duocarmycins; Electrophoresis, Gel, Pulsed-Field; Guanine; HeLa Cells; Humans; Indoles; Macromolecular Substances; Pyrrolidinones; Structure-Activity Relationship; Tumor Stem Cell Assay | 1994 |
Express protocol for generating G+A sequencing ladders.
Topics: Adenine; Animals; Base Sequence; Chironomidae; DNA; Guanine; Molecular Sequence Data; Repetitive Sequences, Nucleic Acid; Sequence Analysis, DNA | 1995 |
Interaction of mithramycin with isolated GC and CG sites.
Topics: Adenine; Base Sequence; Binding Sites; Carbohydrate Sequence; Cytosine; Deoxyribonuclease I; DNA; Electrophoresis, Polyacrylamide Gel; Guanine; Hydroxyl Radical; Molecular Sequence Data; Molecular Structure; Plicamycin; Thymine | 1994 |
In vivo and in vitro replication consequences of stereoisomeric benzo[a]pyrene-7,8-dihydrodiol 9,10-epoxide adducts on adenine N6 at the second position of N-ras codon 61.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adenine; Base Sequence; Binding Sites; Blotting, Southern; Codon; DNA; DNA Adducts; DNA Primers; DNA Repair; DNA Replication; Escherichia coli; Genes, ras; Guanine; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Point Mutation; Stereoisomerism; Templates, Genetic | 1995 |
G to A transitions and G to T transversions in codon 12 of the Ki-ras oncogene isolated from mouse lung tumors induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and related DNA methylating and pyridyloxobutylating agents.
Topics: Adenine; Animals; Base Sequence; Carcinogens; Codon; Dimethylnitrosamine; DNA, Neoplasm; Female; Genes, ras; Guanine; Lung Neoplasms; Methylation; Mice; Mice, Inbred A; Nitrosamines; Point Mutation; Polymorphism, Restriction Fragment Length; Pyridines; Thymine | 1993 |
Possible gene dose effect of a mutant cardiac beta-myosin heavy chain gene on the clinical expression of familial hypertrophic cardiomyopathy.
Topics: Adenine; Adult; Amino Acid Sequence; Animals; Base Sequence; Cardiomyopathy, Hypertrophic; Chickens; Codon; DNA Primers; Echocardiography; Female; Glutamates; Glutamic Acid; Guanine; Humans; Lysine; Male; Molecular Sequence Data; Myocardium; Myosins; Pedigree; Point Mutation; Polymerase Chain Reaction; Rats; Sequence Homology, Amino Acid | 1994 |
Changes in purine nucleotide content in the lymphocyte subpopulations of patients infected with HIV.
Topics: Adenine; Adenosine Diphosphate; Adenosine Triphosphate; Adult; CD4-Positive T-Lymphocytes; Female; Guanine; Guanosine Diphosphate; Guanosine Triphosphate; HIV Infections; HIV Seropositivity; HIV-1; Humans; Lymphocyte Subsets; Male; Middle Aged; Purine Nucleotides; T-Lymphocyte Subsets | 1994 |
Development of methods for measuring biological markers of formaldehyde exposure.
Topics: Adenine; Animals; Biomarkers; Cell Nucleus; Cells, Cultured; Chromatography, Gas; DNA; DNA Adducts; Dose-Response Relationship, Drug; Electrophoresis; Formaldehyde; Guanine; Humans; Lymphocytes; Male; Mass Spectrometry; Nucleosides; Nucleotides; Rats; Rats, Inbred F344; Sensitivity and Specificity | 1994 |
RNA tertiary structure of the HIV RRE domain II containing non-Watson-Crick base pairs GG and GA: molecular modeling studies.
Topics: Adenine; Base Composition; Base Sequence; Computer Simulation; Genes, rev; Guanine; HIV; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; RNA, Viral; Sodium; Water | 1994 |
Genetic analysis of a polymorphism in the human apolipoprotein A-I gene promoter: effect on plasma HDL-cholesterol levels.
Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; Alleles; Apolipoprotein A-I; Cholesterol, HDL; Female; Guanine; Homozygote; Humans; Male; Middle Aged; Polymorphism, Genetic; Promoter Regions, Genetic | 1994 |
Purification and biochemical characterization of recombinant N-methylpurine-DNA glycosylase of the mouse.
Topics: Adenine; Amino Acid Sequence; Animals; DNA; DNA Glycosylases; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Guanine; Hydrogen-Ion Concentration; Kinetics; Magnesium Chloride; Methylation; Mice; Molecular Sequence Data; N-Glycosyl Hydrolases; Recombinant Proteins; Sodium Chloride; Spermine; Substrate Specificity | 1994 |
A mitochondrial DNA mutation at nucleotide pair 14459 of the NADH dehydrogenase subunit 6 gene associated with maternally inherited Leber hereditary optic neuropathy and dystonia.
Topics: Adenine; Adolescent; Amino Acid Sequence; Animals; Base Sequence; Child; Codon; Conserved Sequence; DNA, Mitochondrial; Female; Guanine; Haplotypes; Hispanic or Latino; Humans; Indians, North American; Macromolecular Substances; Male; Molecular Sequence Data; NADH Dehydrogenase; Optic Atrophies, Hereditary; Pedigree; Phylogeny; Point Mutation; Restriction Mapping | 1994 |
A polymorphism (G-->A transition) in the -78 position of the apolipoprotein A-I promoter increases transcription efficiency.
Topics: Adenine; Apolipoprotein A-I; Base Sequence; Guanine; Humans; Molecular Sequence Data; Mutation; Nuclear Proteins; Oligodeoxyribonucleotides; Point Mutation; Polymorphism, Genetic; Promoter Regions, Genetic; Transcription, Genetic; Tumor Cells, Cultured | 1994 |
[Sensitivities to other antiviral drugs and thymidine kinase activity of aciclovir-resistant herpes simplex virus type 1].
Topics: Acyclovir; Adenine; Antiviral Agents; Drug Resistance, Microbial; Ganciclovir; Guanine; Herpesvirus 1, Human; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Thymidine Kinase; Vidarabine | 1994 |
Functional and biological properties of an avian variant long terminal repeat containing multiple A to G conversions in the U3 sequence.
Topics: Adenine; Animals; Avian Leukosis Virus; Base Composition; Base Sequence; Cell Division; Cells, Cultured; Chick Embryo; DNA, Viral; Genetic Vectors; Guanine; Molecular Sequence Data; Mutation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Repetitive Sequences, Nucleic Acid; RNA Splicing; Sequence Homology, Nucleic Acid; Transduction, Genetic | 1994 |
The exchange of the discriminator base A73 for G is alone sufficient to convert human tRNA(Leu) into a serine-acceptor in vitro.
Topics: Acylation; Adenine; Base Sequence; DNA-Directed RNA Polymerases; Guanine; Humans; Leucine; Molecular Sequence Data; Mutagenesis; Nucleic Acid Conformation; Protein Biosynthesis; RNA, Transfer, Leu; RNA, Transfer, Ser; Serine; Viral Proteins | 1994 |
A simple method for N-15 labelling of exocyclic amino groups in synthetic oligodeoxynucleotides.
Topics: 2-Aminopurine; Adenine; Ammonia; Base Sequence; Chromatography, High Pressure Liquid; Cytosine; Guanine; Isotope Labeling; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Nitrogen Isotopes; Oligodeoxyribonucleotides | 1994 |
Solution structure of a purine.purine.pyrimidine DNA triplex containing G.GC and T.AT triples.
Topics: Adenine; Base Composition; Base Sequence; Computer Graphics; Cytosine; DNA; Guanine; Hydrogen Bonding; Macromolecular Substances; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Purines; Pyrimidines; Thymine | 1993 |
Biological actions of purines on rat megakaryocytes: potentiation by adenine of the purinoceptor-operated cytoplasmic Ca2+ oscillation.
Topics: Adenine; Adenosine Triphosphate; Animals; Calcium; Cytoplasm; Drug Synergism; Electrophysiology; Guanine; Isoquinolines; Megakaryocytes; Potassium Channels; Protein Kinase C; Purines; Rats; Receptors, Purinergic | 1994 |
G to A polymorphism in the CACNLG gene.
Topics: Adenine; Base Sequence; Calcium Channels; Chromosome Mapping; Chromosomes, Human, Pair 17; DNA Primers; Genetic Predisposition to Disease; Guanine; Humans; Malignant Hyperthermia; Molecular Sequence Data; Polymerase Chain Reaction; Polymorphism, Genetic | 1993 |
Tetraplex folding of telomere sequences and the inclusion of adenine bases.
Topics: Adenine; Base Sequence; DNA; Guanine; Molecular Sequence Data; Nucleic Acid Conformation; Telomere | 1994 |
Raman microspectroscopic study of low-pH-induced changes in DNA structure of polytene chromosomes.
Topics: Adenine; Animals; Base Composition; Cattle; Chironomidae; Chromosomes; Cytosine; DNA; Guanine; Hydrogen-Ion Concentration; Nucleic Acid Conformation; Protons; Spectrum Analysis, Raman; Thymine; Thymus Gland | 1994 |
Crystal structure of a mispaired dodecamer, d(CGAGAATTC(O6Me)GCG)2, containing a carcinogenic O6-methylguanine.
Topics: Adenine; Base Composition; Base Sequence; Carcinogens; Crystallization; Crystallography, X-Ray; Guanine; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Molecular Structure; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Software | 1994 |
Interaction of the NH2- and COOH-terminal domains of the FLP recombinase with the FLP recognition target sequence.
Topics: Adenine; Base Sequence; Binding Sites; Bromodeoxyuridine; Deoxyribonuclease I; DNA Nucleotidyltransferases; DNA, Fungal; Fungal Proteins; Guanine; Methylation; Molecular Sequence Data; Peptides; Saccharomyces cerevisiae; Substrate Specificity; Ultraviolet Rays | 1994 |
Guanine-1,N6-ethenoadenine base pairs in the crystal structure of d(CGCGAATT(epsilon dA)GCG).
Topics: Adenine; Base Composition; Base Sequence; Child, Preschool; Crystallography, X-Ray; Guanine; Humans; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Oligodeoxyribonucleotides | 1994 |
An A-to-G transition at nucleotide pair 11084 in the ND4 gene may be an mtDNA polymorphism.
Topics: Adenine; DNA, Mitochondrial; Guanine; Humans; MELAS Syndrome; Mutation; Polymorphism, Genetic | 1993 |
Alkylation of DNA by melphalan with special reference to adenine derivatives and adenine-guanine cross-linking.
Topics: Adenine; Adenosine Monophosphate; Alkylation; Animals; Cross-Linking Reagents; Deoxyadenosines; DNA; Guanine; In Vitro Techniques; Magnetic Resonance Spectroscopy; Mass Spectrometry; Melphalan; Salmon | 1993 |
Genetic consequences of tolerance to methylation DNA damage in mammalian cells.
Topics: Adenine; Adenine Phosphoribosyltransferase; Animals; Aza Compounds; Base Sequence; Cell Survival; CHO Cells; Cricetinae; DNA; DNA Damage; Drug Resistance; Guanine; Methylation; Methylnitrosourea; Molecular Sequence Data; Mutation; Ouabain; Thioguanine | 1993 |
A distant 10-bp sequence specifies the boundaries of a programmed DNA deletion in Tetrahymena.
Topics: Adenine; Animals; Base Sequence; DNA, Protozoan; Gene Deletion; Gene Rearrangement; Guanine; Molecular Sequence Data; Tetrahymena thermophila | 1993 |
Mutational heterogeneity among individual tumors in a case of multiple primary malignancy of the colon.
Topics: Adenine; Adenocarcinoma; Adenoma; Aged; Alleles; Base Sequence; Carcinoma; Codon; Colonic Neoplasms; DNA, Neoplasm; Exons; Gene Expression Regulation, Neoplastic; Genes, ras; Guanine; Humans; Male; Mutation; Neoplasms, Multiple Primary | 1993 |
13C NMR analysis of intercompartmental flow of one-carbon units into choline and purines in Saccharomyces cerevisiae.
Topics: Adenine; Carbon Isotopes; Choline; Formates; Genotype; Glycine; Guanine; Magnetic Resonance Spectroscopy; Models, Biological; Purines; Saccharomyces cerevisiae; Serine | 1994 |
The effect of purine phosphonomethoxyalkyl derivatives on DNA synthesis in CHO Chinese hamster cells.
Topics: Adenine; Animals; Antiviral Agents; CHO Cells; Cricetinae; Cricetulus; Cytarabine; DNA Damage; DNA Replication; Dose-Response Relationship, Drug; Guanine; Organophosphonates; Organophosphorus Compounds; Zidovudine | 1993 |
G-->A mutations in p53 and Ha-ras genes in esophageal papillomas induced by N-nitrosomethylbenzylamine in two strains of rats.
Topics: Adenine; Animals; Base Sequence; Carcinogens; Dimethylnitrosamine; Esophageal Neoplasms; Genes, p53; Genes, ras; Guanine; Molecular Sequence Data; Papilloma; Point Mutation; Rats; Rats, Inbred F344 | 1994 |
All four known cyclic adducts formed in DNA by the vinyl chloride metabolite chloroacetaldehyde are released by a human DNA glycosylase.
Topics: Acetaldehyde; Adenine; Animals; Base Sequence; Cattle; Cytosine; DNA; DNA Glycosylases; DNA-Binding Proteins; Guanine; HeLa Cells; Humans; Molecular Sequence Data; N-Glycosyl Hydrolases; Oligonucleotide Probes | 1994 |
A systematic method for studying the spatial distribution of water molecules around nucleic acid bases.
Topics: Adenine; Base Sequence; Crystallography, X-Ray; Cytosine; Databases, Factual; DNA; Guanine; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Solvents; Structure-Activity Relationship; Thymine; Water | 1993 |
Hypertrophic cardiomyopathy and increased number of CAG repeats in the androgen receptor gene.
Topics: Adenine; Aged; Cardiomyopathy, Hypertrophic; Cytosine; Guanine; Humans; Male; Muscular Dystrophies; Receptors, Androgen; Repetitive Sequences, Nucleic Acid | 1993 |
Purine metabolism by intracellular Chlamydia psittaci.
Topics: Adenine; Animals; Cell Line; Chlamydophila psittaci; Cricetinae; Guanine; Guanosine; Mice; Nucleic Acids; Pentostatin; Purine Nucleotides; Purines | 1993 |
Characterization of the alterations in purine nucleotide metabolism in hypoxanthine-guanine phosphoribosyltransferase-deficient rat neuroma cell line.
Topics: Adenine; Adenine Nucleotides; Animals; Formates; Guanine; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Lesch-Nyhan Syndrome; Neuroma; Purine Nucleotides; Rats; Tumor Cells, Cultured; Xanthine; Xanthines | 1993 |
Occurrence of a particular base substitution (3243 A to G) in mitochondrial DNA of tissues of ageing humans.
Topics: Adenine; Adult; Aged; Aged, 80 and over; Aging; Animals; Base Sequence; DNA, Mitochondrial; Guanine; Hominidae; Humans; Infant, Newborn; Middle Aged; Molecular Sequence Data; Oligodeoxyribonucleotides; Organ Specificity; Point Mutation; Polymerase Chain Reaction; Templates, Genetic | 1993 |
Homologous recognition and triplex formation promoted by RecA protein between duplex oligonucleotides and single-stranded DNA.
Topics: Adenine; Base Sequence; Cytosine; DNA, Bacterial; DNA, Single-Stranded; Escherichia coli; Exonucleases; Guanine; Hydrogen Bonding; Kinetics; Methylation; Molecular Sequence Data; Molecular Structure; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Phenanthrolines; Rec A Recombinases; Substrate Specificity; Temperature | 1993 |
Quantitative relationship between ethylated DNA bases and gene mutation at two loci in CHO cells.
Topics: Adenine; Alkylating Agents; Alkylation; Animals; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; DNA; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Ethylnitrosourea; Guanine; Hypoxanthine Phosphoribosyltransferase; Mutagenicity Tests; Mutation; Sodium-Potassium-Exchanging ATPase; Sulfuric Acid Esters | 1993 |
Synthesis and antiviral activity of carbocyclic oxetanocin analogues (C-OXT-A, C-OXT-G) and related compounds. II.
Topics: Adenine; Antiviral Agents; Guanine; Herpesvirus 3, Human; Magnetic Resonance Spectroscopy; Phosphorylation; Simplexvirus; Structure-Activity Relationship; Thymidine Kinase | 1993 |
Phenotypic heterogeneity in families with the myoclonic epilepsy and ragged-red fiber disease point mutation in mitochondrial DNA.
Topics: Adenine; Adult; Base Sequence; Biopsy; Citrate (si)-Synthase; Cytochrome-c Oxidase Deficiency; DNA, Mitochondrial; Electron Transport Complex IV; Family; Female; Guanine; Humans; Male; MERRF Syndrome; Middle Aged; Mitochondria, Muscle; Molecular Sequence Data; Muscles; NADH Dehydrogenase; Oligodeoxyribonucleotides; Pedigree; Phenotype; Point Mutation; Polymerase Chain Reaction; RNA, Transfer, Lys; Succinate Dehydrogenase | 1993 |
Structural studies of the 5'-phenazinium-tethered matched and G-A-mismatched DNA duplexes by NMR spectroscopy.
Topics: Adenine; Base Sequence; DNA; Guanine; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Molecular Structure; Nucleic Acid Conformation; Phenazines; Protons; Temperature; Thermodynamics | 1993 |
Graphic analysis of codon usage strategy in 1490 human proteins.
Topics: Adenine; Codon; Cytosine; DNA; Guanine; Humans; Mathematical Computing; Models, Genetic; Proteins; Thymine | 1993 |
Copper ion-mediated modification of bases in DNA in vitro by benzoyl peroxide.
Topics: Adenine; Benzoyl Peroxide; Copper; DNA; DNA Damage; Drug Interactions; Guanine; Humans; Plasmids; Purines; Pyrimidines | 1993 |
Heterochromatin study demonstrating the non-linearity of fluorometry useful for calculating genomic base composition.
Topics: Adenine; Base Composition; Benzimidazoles; Cell Nucleus; Cytosine; DNA; Flow Cytometry; Fluorometry; Genome; Guanine; Heterochromatin; Karyotyping; Mathematics; Plants; Plicamycin; Thymine | 1993 |
Alternating d(GA)n DNA sequences form antiparallel stranded homoduplexes stabilized by the formation of G.A base pairs.
Topics: Adenine; Base Composition; Base Sequence; DNA; Guanine; Hydrogen-Ion Concentration; Models, Molecular; Molecular Sequence Data; Molecular Structure; Nucleic Acid Conformation | 1993 |
Nucleotide sequence analysis of the precore region in patients with fulminant hepatitis B in the United States.
Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; Base Sequence; DNA, Viral; Female; Gene Amplification; Guanine; Hepatitis B; Hepatitis B e Antigens; Hepatitis B virus; Humans; Male; Middle Aged; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Sequence Analysis, DNA; United States | 1993 |
Cloning and characterization of a mouse 3-methyladenine/7-methyl-guanine/3-methylguanine DNA glycosylase cDNA whose gene maps to chromosome 11.
Topics: Adenine; Amino Acid Sequence; Animals; Base Sequence; Blotting, Southern; Cell Nucleus; Chromosome Mapping; Chromosomes; Cloning, Molecular; DNA; DNA Glycosylases; DNA Repair; Escherichia coli; Gene Expression; Guanine; Humans; Mice; Molecular Sequence Data; N-Glycosyl Hydrolases; Rats; RNA, Messenger; Sequence Homology, Amino Acid | 1993 |
Multiple symmetric lipomas with high levels of mtDNA with the tRNA(Lys) A-->G(8344) mutation as the only manifestation of disease in a carrier of myoclonus epilepsy and ragged-red fibers (MERRF) syndrome.
Topics: Adenine; Adolescent; Adult; Cells, Cultured; Child, Preschool; Chromosome Banding; Chromosome Deletion; Chromosomes, Human, Pair 6; DNA, Mitochondrial; Female; Guanine; Heterozygote; Humans; Lipoma; Male; MERRF Syndrome; Mutation; Polymerase Chain Reaction; RNA, Transfer, Lys; X Chromosome | 1993 |
Surface-enhanced Raman spectroscopic detection of CO2-(3), SO2-(3), and nucleic acid bases using polyvinyl alcohol film doped with Ag fine particles.
Topics: Adenine; Carbonates; Cytosine; DNA; Guanine; Membranes, Artificial; Particle Size; Polyvinyl Alcohol; Scattering, Radiation; Silver; Spectrum Analysis, Raman; Sulfites; Surface Properties; Thymine; Uracil | 1993 |
Linear dichroism demonstrates that the bases in poly[d(AC)].poly[d (GT)] and poly[d(AG)].poly[d(CT)] are inclined from perpendicular to the helix axis.
Topics: Adenine; Chemical Phenomena; Chemistry, Physical; Cytosine; Guanine; Molecular Conformation; Polydeoxyribonucleotides; Spectrum Analysis; Thymine | 1993 |
Genotypic classification of colorectal adenocarcinoma. Biologic behavior correlates with K-ras-2 mutation type.
Topics: Adenine; Adenocarcinoma; Aspartic Acid; Biology; Codon; Colonic Neoplasms; Gene Frequency; Genes, ras; Genotype; Guanine; Humans; Liver Neoplasms; Lymphatic Metastasis; Mutation; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Rectal Neoplasms | 1993 |
Solution structure of selenocysteine-inserting tRNA(Sec) from Escherichia coli. Comparison with canonical tRNA(Ser).
Topics: Adenine; Base Sequence; Escherichia coli; Guanine; Lead; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; RNA, Transfer, Amino Acid-Specific; RNA, Transfer, Ser; Selenocysteine; Sequence Homology, Nucleic Acid; Single-Strand Specific DNA and RNA Endonucleases | 1993 |
RNA polymerase bypass at sites of dihydrouracil: implications for transcriptional mutagenesis.
Topics: Adenine; Base Sequence; DNA Damage; DNA Repair; DNA-Directed RNA Polymerases; Escherichia coli; Guanine; Kinetics; Molecular Sequence Data; Mutagenesis; Mutagenesis, Insertional; Oligodeoxyribonucleotides; Point Mutation; RNA; Substrate Specificity; Templates, Genetic; Transcription, Genetic; Uracil; Viral Proteins | 1995 |
A free energy analysis of nucleic acid base stacking in aqueous solution.
Topics: Adenine; Base Composition; Calorimetry; Cytosine; DNA; Electrochemistry; Guanine; Magnetic Resonance Spectroscopy; Mathematics; Models, Theoretical; Thermodynamics; Thymine | 1995 |
8-Methoxypsoralen photoadduct formation in complementary oligonucleotides containing a cross-linkable site.
Topics: Adenine; Base Composition; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Cytosine; DNA Adducts; Guanine; Light; Methoxsalen; Oligonucleotides; Photosensitizing Agents; Thymine; Tritium; Ultraviolet Rays | 1995 |
A rare G6490-->A substitution at the last nucleotide of exon 10 of the glucocerebrosidase gene in two unrelated Italian Gaucher patients.
Topics: Adenine; Child, Preschool; Exons; Gaucher Disease; Genetic Testing; Glucosylceramidase; Guanine; Humans; Infant; Italy; Male; Mutation; Pedigree; Polymorphism, Single-Stranded Conformational | 1995 |
Evidence against heterozygous coagulation factor V 1691 G-->A mutation with resistance to activated protein C being a risk factor for coronary artery disease and myocardial infarction.
Topics: Adenine; Adult; Aged; Aged, 80 and over; Coronary Disease; Disease Susceptibility; Drug Resistance; Factor V; Female; Guanine; Heterozygote; Humans; Male; Middle Aged; Myocardial Infarction; Point Mutation; Prevalence; Protein C; Risk Factors | 1995 |
A G+1-->A transversion at the 5' splice site of intron 69 of the dystrophin gene causing the absence of peripheral nerve Dp116 and severe clinical involvement in a DMD patient.
Topics: Adenine; Base Sequence; Child; DNA; Dystrophin; Guanine; Humans; Introns; Male; Molecular Sequence Data; Muscular Dystrophies; Point Mutation; RNA Splicing; RNA, Messenger; Sural Nerve | 1995 |
Hydration of the DNA bases is local.
Topics: Adenine; Base Sequence; Crystallography, X-Ray; Cytosine; Databases, Factual; DNA; Guanine; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Thymine | 1995 |
Clinical phenotypes, insulin secretion, and insulin sensitivity in kindreds with maternally inherited diabetes and deafness due to mitochondrial tRNALeu(UUR) gene mutation.
Topics: Adenine; Adolescent; Adult; Aged; Arginine; Blood Glucose; Body Mass Index; C-Peptide; Child; Child, Preschool; Deafness; Diabetes Mellitus, Type 2; Female; Genomic Imprinting; Glucose Tolerance Test; Glycated Hemoglobin; Guanine; Humans; Insulin; Insulin Secretion; Male; Middle Aged; Pedigree; Periodicity; Phenotype; Point Mutation; Reference Values; RNA, Transfer, Leu; Sex Characteristics | 1996 |
MPD and DNA bending in crystals and in solution.
Topics: Adenine; Base Sequence; Crystallization; Crystallography, X-Ray; DNA; Glycols; Guanine; In Vitro Techniques; Models, Molecular; Molecular Sequence Data; Molecular Structure; Nucleic Acid Conformation; Solutions | 1996 |
G --> A mutation of ras genes and infrequent p53 gene mutation in rat transplantable thyroid carcinoma lines from tumors induced in vivo by N-bis(2-hydroxypropyl)nitrosamine.
Topics: Adenine; Animals; Base Sequence; Carcinogens; Exons; Genes, p53; Genes, ras; Guanine; Molecular Sequence Data; Neoplasm Transplantation; Nitrosamines; Point Mutation; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Rats; Thyroid Neoplasms | 1996 |
Conformational studies of depurinating DNA adducts from syn-dibenzo[a,l]pyrene diolepoxide.
Topics: Adenine; Benzopyrenes; Carcinogens; DNA Adducts; Electrons; Guanine; Models, Molecular; Molecular Conformation; Spectrometry, Fluorescence | 1996 |
Structural integrity of the gamma-carboxyglutamic acid domain of human blood coagulation factor IXa Is required for its binding to cofactor VIIIa.
Topics: Adenine; Amino Acid Sequence; Arginine; Base Sequence; Binding Sites; DNA; DNA Mutational Analysis; Exons; Factor IX; Factor IXa; Factor VIIIa; Factor X; Glycine; Guanine; Hemophilia B; Humans; Kinetics; Mathematics; Models, Theoretical; Molecular Sequence Data; Point Mutation; Prothrombin Time; Triazines | 1996 |
Large-scale study of an A-to-G transition at position 3243 of the mitochondrial gene and IDDM in Japanese patients.
Topics: Adenine; Adolescent; Adult; Age of Onset; Child; Child, Preschool; Diabetes Mellitus, Type 1; Diabetic Coma; Diabetic Ketoacidosis; DNA, Mitochondrial; Female; Guanine; Humans; Infant; Japan; Male; Point Mutation; Polymerase Chain Reaction | 1996 |
Targeted A --> T and G --> T mutations induced by site-specific deoxyadenosine and deoxyguanosine adducts, respectively, from the (+)-anti-diol epoxide of dibenz[a,j]anthracene in M13mp7L2.
Topics: Adenine; Base Sequence; Benz(a)Anthracenes; Deoxyadenosines; Deoxyguanosine; DNA Adducts; DNA, Single-Stranded; Escherichia coli; Guanine; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutagens; Oligodeoxyribonucleotides; Plasmids; Point Mutation; Thymine; Transfection | 1996 |
RNA editing in Drosophila 4f-rnp gene nuclear transcripts by multiple A-to-G conversions.
Topics: Adenine; Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; DNA; Drosophila melanogaster; Drosophila Proteins; Guanine; Molecular Sequence Data; Nucleic Acid Heteroduplexes; Ribonucleoproteins; RNA Editing; RNA-Binding Proteins | 1996 |
Structural mechanics of bent DNA.
Topics: Adenine; Base Composition; Base Sequence; Biomechanical Phenomena; Chromosomes; Crystallography; Cytosine; DNA; Genetic Code; Guanine; Humans; Models, Structural; Nucleic Acid Conformation; Thymine | 1996 |
The 1691 G-->A mutation in the factor V gene: relationship to activated protein C (APC) resistance and thrombosis in 65 patients.
Topics: Adenine; Adolescent; Adult; Aged; Case-Control Studies; Drug Resistance; Factor V; Female; Fibrinolytic Agents; Guanine; Humans; Male; Middle Aged; Mutation; Pedigree; Phenotype; Protein C; Thrombosis | 1996 |
The expanding clinical phenotype of the tRNA(Leu(UUR)) A-->G mutation at np 3243 of mitochondrial DNA: diabetic embryopathy associated with mitochondrial cytopathy.
Topics: Abnormalities, Multiple; Adenine; Adult; Anus, Imperforate; Base Sequence; DNA, Mitochondrial; Female; Guanine; Humans; Infant, Newborn; Kidney; Male; MELAS Syndrome; Middle Aged; Molecular Sequence Data; Phenotype; Point Mutation; Pregnancy; Pregnancy in Diabetics; RNA, Transfer, Leu | 1996 |
MDL 74,968, a new acyclonucleotide analog: activity against human immunodeficiency virus in vitro and in the hu-PBL-SCID.beige mouse model of infection.
Topics: Adenine; Animals; Antiviral Agents; Cell Line; Cells, Cultured; Didanosine; DNA, Viral; Guanine; HIV Infections; HIV-1; HIV-2; Humans; Male; Mice; Mice, SCID; Monocytes; Organophosphonates; Spleen; T-Lymphocytes; Zidovudine | 1996 |
Sequence preference of 7,12-dimethylbenz[a]anthracene-syn-diol epoxide-DNA binding in the mouse H-ras gene detected by UvrABC nucleases.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenine; Animals; Binding Sites; Codon; DNA Adducts; Electrophoresis, Polyacrylamide Gel; Endodeoxyribonucleases; Escherichia coli Proteins; Genes, ras; Guanine; Humans; Kinetics; Mice; Molecular Structure | 1996 |
Cleavage of oligodeoxyribonucleotides from controlled-pore glass supports and their rapid deprotection by gaseous amines.
Topics: Adenine; Ammonia; Base Sequence; Cytosine; Gases; Glass; Guanine; Methylamines; Molecular Sequence Data; Oligodeoxyribonucleotides; Organophosphorus Compounds; Pressure | 1996 |
Detection of the apolipoprotein B-100 arg(3500) > gl mutation in familial defective apoB-100 by temperature-gradient gel electrophoresis.
Topics: Adenine; Apolipoprotein B-100; Apolipoproteins B; Arteriosclerosis; Blood Protein Electrophoresis; Codon; DNA Mutational Analysis; Genetic Testing; Guanine; Humans; Hyperlipidemia, Familial Combined; Hyperlipoproteinemia Type II; Point Mutation; Receptors, LDL | 1996 |
An approximate approach to DNA denaturation.
Topics: Adenine; Base Composition; Cytosine; DNA; DNA, Bacterial; Guanine; Hydrogen Bonding; Models, Chemical; Models, Structural; Nucleic Acid Conformation; Nucleic Acid Denaturation; Polydeoxyribonucleotides; Thermodynamics; Thymine; Time Factors | 1995 |
Inhalation exposure of rats and mice to 1,3-butadiene induces N6-adenine adducts of epoxybutene detected by 32P-postlabeling and HPLC.
Topics: Adenine; Administration, Inhalation; Alkylation; Animals; Butadienes; Cattle; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; DNA Adducts; Epoxy Compounds; Guanine; In Vitro Techniques; Mice; Phosphorus Radioisotopes; Rats | 1996 |
A novel A-->G mutation in intron I of the hepatic lipase gene leads to alternative splicing resulting in enzyme deficiency.
Topics: Adenine; Alternative Splicing; Amino Acid Sequence; Base Sequence; Child; Chronic Disease; DNA Primers; Exons; Female; Guanine; Humans; Hypertriglyceridemia; Introns; Lipase; Liver; Male; Middle Aged; Molecular Sequence Data; Myocardial Infarction; Pancreatitis; Point Mutation; Polymerase Chain Reaction; Reference Values | 1996 |
Lack of expansion of cytosine adenine guanine trinucleotide repeat in the dentatorubral and pallidoluysian atrophy gene in Swedish schizophrenic patients.
Topics: Adenine; Alleles; Atrophy; Autoradiography; Chromosomes, Human, Pair 13; Cytosine; Dentate Gyrus; Globus Pallidus; Guanine; Humans; Point Mutation; Schizophrenia; Sweden; Trinucleotide Repeats | 1996 |
Acyclic nucleotide analogs derived from 8-azapurines: synthesis and antiviral activity.
Topics: 3T3 Cells; Adenine; Animals; Antiviral Agents; Cell Transformation, Viral; Cytomegalovirus; Cytopathogenic Effect, Viral; Guanine; Herpesvirus 1, Human; Herpesvirus 2, Human; Herpesvirus 3, Human; HIV-1; HIV-2; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred C3H; Molecular Structure; Purines; Sarcoma Viruses, Murine | 1996 |
Rapid purification and characterization of two distinct N-deoxyribosyltransferases of Lactobacillus leichmannii.
Topics: Adenine; Amino Acid Sequence; Blotting, Western; Chromatography, Affinity; Electrophoresis, Polyacrylamide Gel; Guanine; Isoenzymes; Kinetics; Lactobacillus; Molecular Sequence Data; Molecular Weight; Pentosyltransferases; Protein Denaturation; Temperature | 1996 |
RNA quadruplex containing G and A.
Topics: Adenine; Base Sequence; Circular Dichroism; Guanine; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Molecular Structure; Nucleic Acid Conformation; Oligoribonucleotides; Potassium; RNA | 1995 |
Mechanism of mutagenesis induced by cytosine analogs bearing N(4)-substitutions.
Topics: Adenine; Base Composition; Binding Sites; Cytosine; DNA, Bacterial; Escherichia coli; Guanine; Mutagenesis; Mutagens; Nucleosides; Salmonella typhimurium; Thymidine Kinase | 1995 |
Homozygosity for R87H missense mutation and for a rare intron 7 DNA variant (7054G --> A) in the PROC genes of three siblings initially classified as heterozygotes for protein C deficiency.
Topics: Adenine; Adult; Amino Acid Sequence; Base Sequence; DNA; Exons; Genetic Variation; Guanine; Heterozygote; Homozygote; Humans; Introns; Male; Molecular Sequence Data; Mutation; Pedigree; Protein C; Protein C Deficiency | 1996 |
Factor VII G331D: a variant molecule involving replacement of a residue in the substrate-binding region of the catalytic domain.
Topics: Adenine; Base Sequence; Binding Sites; Catalysis; Factor VII; Female; Genetic Variation; Guanine; Heterozygote; Humans; Middle Aged; Molecular Sequence Data; Mutation; Protein Structure, Tertiary | 1996 |
Structural polymorphism of homopurine DNA sequences. d(GGA)n and d(GGGA)n repeats form intramolecular hairpins stabilized by different base-pairing interactions.
Topics: Adenine; Base Composition; Base Sequence; Diethyl Pyrocarbonate; DNA; Electrophoresis, Polyacrylamide Gel; Guanine; Molecular Sequence Data; Nucleic Acid Conformation; Nucleic Acid Denaturation; Oligodeoxyribonucleotides; Repetitive Sequences, Nucleic Acid; Sulfuric Acid Esters; Temperature | 1996 |
A G-to-A substitution at nucleotide position 3316 in mitochondrial DNA is associated with Japanese non-insulin-dependent diabetes mellitus.
Topics: Adenine; Adult; Aged; Child; Diabetes Mellitus, Type 2; DNA, Mitochondrial; Female; Guanine; Humans; Japan; Male; Middle Aged; Mutation | 1996 |
Combined hereditary disorders of haemophilia B Leyden (-6 G-->A) and type 1 von Willebrand disease.
Topics: Adenine; Adult; Child; Factor IX; Female; Guanine; Humans; Male; Middle Aged; Pedigree; Point Mutation; Sequence Analysis, DNA; von Willebrand Diseases | 1996 |
The design of agents to control DNA methylation adducts. Enhanced major groove methylation of DNA by an N-methyl-N-nitrosourea functionalized phenyl neutral red intercalator.
Topics: Adenine; Circular Dichroism; DNA Adducts; DNA Methylation; Drug Design; Ethidium; Guanine; Intercalating Agents; Methylnitrosourea; Neutral Red; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 1996 |
An additional mitochondrial tRNA(Ile) point mutation (A-to-G at nucleotide 4295) causing hypertrophic cardiomyopathy.
Topics: Adenine; Animals; Base Sequence; Biological Evolution; Cardiomyopathy, Hypertrophic; Conserved Sequence; DNA, Mitochondrial; Electron Transport Complex IV; Female; Guanine; Humans; Infant; Male; Molecular Sequence Data; Myocardium; NADPH-Ferrihemoprotein Reductase; Nucleic Acid Conformation; Pedigree; Point Mutation; Polymerase Chain Reaction; RNA, Transfer, Ile; Sequence Homology, Nucleic Acid; Succinate Cytochrome c Oxidoreductase | 1996 |
Macromolecular adducts of butadiene.
Topics: Adenine; Animals; Butadienes; DNA; Epoxy Compounds; Female; Globins; Guanine; Guanosine; Humans; Male; Mice; Rats; Species Specificity | 1996 |
Liquid chromatography/electrospray ionization tandem mass spectroscopy (LC/ESI MS/MS) analysis of 1,2-epoxybutene adducts of purine deoxynucleosides.
Topics: Adenine; Carcinogens; Chromatography, Liquid; DNA Adducts; Epoxy Compounds; Guanine; Mass Spectrometry | 1996 |
Beta-fibrinogen gene-455 G/A polymorphism and fibrinogen levels. Risk factors for coronary artery disease in subjects with NIDDM.
Topics: Adenine; Aged; Coronary Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Fibrinogen; Genotype; Guanine; Humans; Hypertension; Male; Middle Aged; Polymorphism, Genetic; Risk Factors | 1996 |
A curved RNA helix incorporating an internal loop with G.A and A.A non-Watson-Crick base pairing.
Topics: Adenine; Base Composition; Base Sequence; Binding Sites; Crystallography, X-Ray; Guanine; Hydrogen Bonding; Metals; Models, Genetic; Models, Molecular; Nucleic Acid Conformation; Oligoribonucleotides; RNA | 1996 |
Effect of overexpression of E. coli 3-methyladenine-DNA glycosylase I (Tag) on survival and mutation induction in Salmonella typhimurium.
Topics: Adenine; DNA Glycosylases; Escherichia coli; Gene Expression Regulation, Bacterial; Genes, Bacterial; Guanine; Isopropyl Thiogalactoside; Mutagens; Mutation; N-Glycosyl Hydrolases; Nitrosourea Compounds; Salmonella typhimurium; SOS Response, Genetics; Sulfuric Acid Esters; Suppression, Genetic; Transformation, Genetic | 1996 |
Did de novo MELAS common mitochondrial DNA point mutation (mtDNA 3243, A-->G transition) occur in the mother of a proband of a Japanese MELAS pedigree?
Topics: Adenine; Adult; Aged; Aged, 80 and over; Alzheimer Disease; Base Sequence; Family Health; Female; Guanine; Humans; Male; MELAS Syndrome; Middle Aged; Pedigree; Point Mutation; Polymerase Chain Reaction | 1996 |
Radiation-induced DNA damage as a function of hydration. II. Base damage from electron-loss centers.
Topics: Adenine; Animals; Base Composition; Cytosine; DNA; DNA Damage; Electron Spin Resonance Spectroscopy; Electrons; Gas Chromatography-Mass Spectrometry; Guanine; Hydrolysis; Nucleic Acid Conformation; Pyrimidines; Salmon; Thymine | 1996 |
Recurrent G-to-A substitution in a single codon of SREBP cleavage-activating protein causes sterol resistance in three mutant Chinese hamster ovary cell lines.
Topics: Adenine; Animals; Base Sequence; CCAAT-Enhancer-Binding Proteins; CHO Cells; Cholesterol; Clone Cells; Codon; Cricetinae; DNA Primers; DNA-Binding Proteins; Drug Resistance; Guanine; Haplotypes; Helix-Loop-Helix Motifs; Hydroxycholesterols; Nuclear Proteins; Point Mutation; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Sterol Regulatory Element Binding Protein 1; Transcription Factors | 1996 |
Effect of UVM induction on mutation fixation at non-pairing and mispairing DNA lesions.
Topics: Adenine; Bacteriophage M13; Cytosine; DNA, Single-Stranded; DNA, Viral; Escherichia coli; Guanine; Methylnitronitrosoguanidine; Mutagenesis; Mutagens; Transfection; Ultraviolet Rays | 1996 |
Mutagenic DNA base modifications are correlated with lesions in nonneoplastic hepatic tissue of the English sole carcinogenesis model.
Topics: Adenine; Age Factors; Animals; Confounding Factors, Epidemiologic; Fish Diseases; Guanine; Liver Diseases; Liver Neoplasms; Mutagenesis; Precancerous Conditions | 1996 |
G.A and U.U mismatches can stabilize RNA internal loops of three nucleotides.
Topics: Adenine; Base Composition; Base Sequence; Guanine; Oligoribonucleotides; RNA; RNA, Double-Stranded; Structure-Activity Relationship; Thermodynamics; Uracil | 1996 |
Methoxyamine-induced mutagenesis of nucleic acids. A proton NMR study of oligonucleotides containing N4-methoxycytosine paired with adenine or guanine.
Topics: Adenine; Base Composition; Cytosine; Guanine; Hydrogen Bonding; Hydroxylamines; Kinetics; Magnetic Resonance Spectroscopy; Models, Theoretical; Mutagenesis; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Thermodynamics | 1996 |
Specific recognition of A/G and A/7,8-dihydro-8-oxoguanine (8-oxoG) mismatches by Escherichia coli MutY: removal of the C-terminal domain preferentially affects A/8-oxoG recognition.
Topics: Adenine; Amino Acid Sequence; Base Composition; Base Sequence; Binding Sites; DNA Damage; DNA Glycosylases; DNA Repair; Endopeptidases; Escherichia coli; Guanine; Molecular Sequence Data; N-Glycosyl Hydrolases; Oligodeoxyribonucleotides; Peptide Fragments; Sequence Homology, Amino Acid; Substrate Specificity | 1996 |
Repeat expansion detection analysis of (CAG)n tracts in tumor cell lines, testicular tumors, and testicular cancer families.
Topics: Adenine; Autoradiography; Cytosine; DNA, Neoplasm; Female; Guanine; Humans; Male; Oligonucleotide Probes; Ovarian Neoplasms; Pedigree; Polymerase Chain Reaction; Testicular Neoplasms; Trinucleotide Repeats; Tumor Cells, Cultured | 1997 |
K-ras codon 12 and 61 point mutations in bromodeoxyuridine- and N-nitrosomethylurea-induced rat renal mesenchymal tumors.
Topics: Adenine; Animals; Bromodeoxyuridine; Carcinogens; Codon; Female; Genes, ras; Guanine; Kidney Neoplasms; Male; Mesenchymoma; Methylnitrosourea; Neoplasms, Experimental; Point Mutation; Polymerase Chain Reaction; Rats | 1996 |
Determination of CAG repeat length in the androgen-receptor gene using frozen serum.
Topics: Adenine; Cytosine; DNA; Exons; Guanine; Humans; Receptors, Androgen; Repetitive Sequences, Nucleic Acid | 1997 |
Identification and quantitation of DNA adducts from calf thymus DNA exposed to 3,4-epoxy-1-butene.
Topics: Adenine; Animals; Cattle; DNA Adducts; Epoxy Compounds; Guanine; Guanosine; Mutagens | 1997 |
Antiretroviral activities of acyclic nucleoside phosphonates [9-(2-phosphonylmethoxyethyl)adenine, 9-(2-phosphonylmethoxyethyl)guanine, (R)-9-(2-phosphonylmethoxypropyl)adenine, and MDL 74,968] in cell cultures and murine sarcoma virus-infected newborn NM
Topics: Adenine; Animals; Animals, Newborn; Antiviral Agents; Cell Line; Fibroblasts; Guanine; Humans; Mice; Mice, Inbred C3H; Organophosphonates; Organophosphorus Compounds; Retroviridae; Retroviridae Infections; Sarcoma Viruses, Murine; Tenofovir | 1997 |
Structural features of the DNA hairpin d(ATCCTA-GTTA-TAGGAT): formation of a G-A base pair in the loop.
Topics: Adenine; Base Composition; Computer Graphics; DNA; Guanine; Magnetic Resonance Spectroscopy; Models, Molecular; Nucleic Acid Conformation; Oligodeoxyribonucleotides | 1997 |
Effect of the 1-(2'-deoxy-beta-D-ribofuranosyl)-3-nitropyrrole residue on the stability of DNA duplexes and triplexes.
Topics: Adenine; Base Composition; Base Sequence; Calorimetry; Cytosine; Deoxyribonucleosides; DNA; Guanine; Nucleic Acid Conformation; Nucleic Acid Denaturation; Oligodeoxyribonucleotides; Pyrroles; Structure-Activity Relationship; Thermodynamics; Thymine | 1997 |
A mutant RNA pseudoknot that promotes ribosomal frameshifting in mouse mammary tumor virus.
Topics: Adenine; Animals; Base Composition; Base Sequence; Computer Simulation; Frameshifting, Ribosomal; Guanine; Magnetic Resonance Spectroscopy; Mammary Tumor Virus, Mouse; Mice; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Point Mutation; RNA, Viral; Thermodynamics; Uracil | 1997 |
Triple helix formation with purine-rich phosphorothioate-containing oligonucleotides covalently linked to an acridine derivative.
Topics: Acridines; Adenine; Base Composition; Base Sequence; DNA; Guanine; Kinetics; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Purines; Spectrophotometry, Ultraviolet; Thionucleotides; Thymine | 1997 |
Hydrogen-bonded trimers of DNA bases and their interaction with metal cations: ab initio quantum-chemical and empirical potential study.
Topics: Adenine; Base Composition; Calorimetry; Cations; Computer Simulation; Cytosine; DNA; Guanine; Hydrogen Bonding; Metals; Models, Molecular; Molecular Structure; Nucleic Acid Conformation; Software; Thymine | 1997 |
Carbocyclic oxetanocins lacking the C-3' methylene.
Topics: Adenine; Adenosine; Animals; Antiviral Agents; Cells, Cultured; Giant Cells; Guanine; Herpesvirus 1, Human; Herpesvirus 3, Human; HIV-1; HIV-2; Humans; Magnetic Resonance Spectroscopy; Molecular Structure; Viruses | 1997 |
Secondary radical attack on DNA nucleotides: reaction by addition to DNA bases and abstraction from sugars.
Topics: Adenine; Deoxyadenine Nucleotides; Deoxyguanine Nucleotides; DNA; Electron Spin Resonance Spectroscopy; Free Radicals; Gamma Rays; Guanine; Iodoacetamide; Kinetics; Molecular Structure; Oligodeoxyribonucleotides; Thermodynamics; Thymidine Monophosphate; Thymine; Uracil | 1997 |
Hepatocellular carcinoma in patients from northern Sweden with acute intermittent porphyria: morphology and mutations.
Topics: Adenine; Aged; Aged, 80 and over; Alleles; Base Sequence; Carcinoma, Hepatocellular; Cell Division; Codon; DNA Damage; DNA, Viral; Female; Fixatives; Formaldehyde; Genes, p53; Genes, ras; Genes, Tumor Suppressor; Guanine; Heme; Hepatitis B virus; Humans; Hydroxymethylbilane Synthase; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Mutation; Porphyria, Acute Intermittent; Sweden; Tissue Fixation | 1996 |
Fpg protein releases a ring-opened N-7 guanine adduct from DNA that has been modified by sulfur mustard.
Topics: Adenine; Alkylation; Carcinogens; DNA Adducts; DNA-Formamidopyrimidine Glycosylase; Escherichia coli; Escherichia coli Proteins; Guanine; Mustard Gas; N-Glycosyl Hydrolases | 1997 |
Hypoxanthine uptake at the fetal side of human placenta proceeds through a nucleobase-preferring carrier and a non-saturable process.
Topics: Adenine; Adenosine; Biological Transport; Blood Flow Velocity; Female; Fetus; Guanine; Humans; Hypoxanthine; Papaverine; Placenta; Pregnancy; Sodium; Tritium | 1997 |
Tumour necrosis factor alpha gene polymorphisms in rheumatoid arthritis: association with susceptibility to, or severity of, disease?
Topics: Adenine; Adult; Aged; Alleles; Arthritis, Rheumatoid; Base Sequence; Case-Control Studies; Cytosine; Disease Progression; Disease Susceptibility; DNA Primers; Female; Gene Expression Regulation; Gene Frequency; Genes; Genotype; Guanine; HLA-DR4 Antigen; Humans; Male; Middle Aged; Polymorphism, Genetic; Severity of Illness Index; Surveys and Questionnaires; Tumor Necrosis Factor-alpha | 1997 |
Dam methyltransferase from Escherichia coli: kinetic studies using modified DNA oligomers: nonmethylated substrates.
Topics: 2-Aminopurine; Adenine; Base Sequence; DNA Methylation; DNA Probes; DNA, Bacterial; Enzyme Inhibitors; Escherichia coli; Escherichia coli Proteins; Guanine; Hypoxanthine; Kinetics; Molecular Sequence Data; Nucleic Acid Heteroduplexes; Oligonucleotide Probes; Site-Specific DNA-Methyltransferase (Adenine-Specific); Software; Substrate Specificity; Temperature; Thermodynamics; Thymine; Uracil | 1997 |
Validation and steady-state analysis of a power-law model of purine metabolism in man.
Topics: Adenine; Adenine Phosphoribosyltransferase; Guanine; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Kinetics; Models, Biological; Phosphoribosyl Pyrophosphate; Purines; Sensitivity and Specificity; Uric Acid; Xanthine; Xanthines | 1997 |
Intracellular metabolism and action of acyclic nucleoside phosphonates on DNA replication.
Topics: Adenine; Antineoplastic Agents; Cell Line; DNA Replication; DNA-Directed DNA Polymerase; Guanine; Humans; Organophosphonates; Organophosphorus Compounds; Simian virus 40; Tenofovir | 1997 |
Wide variety of point mutations in the H gene of Bombay and para-Bombay individuals that inactivate H enzyme.
Topics: Adenine; Alleles; Aspartic Acid; Base Sequence; DNA Primers; Erythrocytes; Female; Fucosyltransferases; Galactoside 2-alpha-L-fucosyltransferase; Guanine; Humans; Japan; Male; Pedigree; Point Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Sequence Deletion; Tyrosine | 1997 |
Models for the regulation of purine metabolism in rat hepatocytes: evaluation of tracer kinetic experiments.
Topics: Adenine; Animals; Carbon Radioisotopes; Cells, Cultured; Guanine; Guanine Nucleotides; Homeostasis; Hypoxanthine; Kinetics; Liver; Male; Mathematics; Models, Biological; Purine Nucleosides; Purines; Radioisotope Dilution Technique; Rats; Rats, Wistar | 1997 |
Arylsulphatase A pseudodeficiency in vascular dementia and Alzheimer's disease.
Topics: Adenine; Age of Onset; Aged; Alzheimer Disease; Brain; Cerebroside-Sulfatase; Dementia, Vascular; Female; Gene Frequency; Genetic Markers; Guanine; Humans; Male; Point Mutation; Polymorphism, Genetic; Risk Factors | 1997 |
G --> A hypermutation does not result from polymerase chain reaction.
Topics: Adenine; Amino Acid Sequence; Animals; Guanine; HIV Envelope Protein gp120; Lentivirus; Membrane Glycoproteins; Molecular Sequence Data; Nucleic Acid Heteroduplexes; Point Mutation; Polymerase Chain Reaction; Simian Immunodeficiency Virus; Viral Envelope Proteins | 1997 |
Glucose-6-phosphate dehydrogenase Durham: a de novo mutation associated with chronic hemolytic anemia.
Topics: Adenine; Amino Acid Sequence; Anemia, Hemolytic, Congenital Nonspherocytic; Arginine; Base Sequence; Child; Chronic Disease; Genetic Linkage; Glucosephosphate Dehydrogenase; Guanine; Humans; Lysine; Male; Point Mutation; Sequence Analysis, DNA; X Chromosome | 1997 |
Identification of a new thyroglobulin variant: a guanine-to-adenine transition resulting in the substitution of arginine 2510 by glutamine.
Topics: Adenine; Alleles; Animals; Arginine; Cattle; Gene Frequency; Genetic Variation; Glutamine; Goiter; Guanine; Humans; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Rats; RNA-Directed DNA Polymerase; Thyroglobulin; Thyroid Gland | 1997 |
Naturally occurring hepatitis B virus genomes bearing the hallmarks of retroviral G-->A hypermutation.
Topics: Adenine; Base Sequence; Carrier State; Dinucleoside Phosphates; DNA Primers; DNA, Viral; Frameshift Mutation; Genome, Viral; Guanine; Hepatitis B; Hepatitis B virus; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Polymerase Chain Reaction; Sequence Alignment; Sequence Deletion | 1997 |
The detailed structure of tandem G.A mismatched base-pair motifs in RNA duplexes is context dependent.
Topics: Adenine; Base Composition; Base Sequence; DNA-Directed RNA Polymerases; Guanine; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Nucleic Acid Conformation; Nucleic Acid Heteroduplexes; Oligoribonucleotides; RNA; Templates, Genetic; Viral Proteins | 1997 |
Increased trinucleotide repeat instability with advanced maternal age.
Topics: Adenine; Animals; Ataxin-1; Ataxins; Breeding; Cytosine; Female; Guanine; Male; Maternal Age; Mice; Mice, Inbred Strains; Mice, Transgenic; Nerve Tissue Proteins; Nuclear Proteins; Oogenesis; Trinucleotide Repeats | 1997 |
RNA editing generates a diverse array of transcripts encoding squid Kv2 K+ channels with altered functional properties.
Topics: Adenine; Amino Acid Sequence; Animals; Base Sequence; Decapodiformes; DNA, Complementary; Electrophysiology; Exons; Gene Expression; Genotype; Guanine; Molecular Sequence Data; Mutagenesis; Optic Lobe, Nonmammalian; Potassium Channels; RNA Editing; RNA, Messenger; Transcription, Genetic | 1997 |
Asymmetry in Flp-mediated cleavage.
Topics: Adenine; DNA; DNA Methylation; DNA Nucleotidyltransferases; Guanine; Hot Temperature; Oligodeoxyribonucleotides; Substrate Specificity; Thionucleotides | 1997 |
Irinotecan hydrochloride (CPT-11) resistance identified by K-ras mutation in patients with progressive colon cancer after treatment with 5-fluorouracil (5-FU).
Topics: Adenine; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Camptothecin; Codon; Colonic Neoplasms; Disease Progression; DNA, Neoplasm; Drug Resistance, Neoplasm; Exons; Female; Fluorouracil; Forecasting; Genes, ras; Guanine; Humans; Irinotecan; Male; Middle Aged; Mutation; Prognosis; Retreatment; Sequence Analysis, DNA; Survival Rate; Thymine; Treatment Failure | 1997 |
Hairpin structure of an RNA 28-mer, which contains a sequence of the enzyme component of a hammerhead ribozyme system: evidence for tandem G:A pairs that are not of side-by-side type.
Topics: Adenine; Base Composition; Guanine; Magnetic Resonance Spectroscopy; Nitrogen Isotopes; Nucleic Acid Conformation; Repetitive Sequences, Nucleic Acid; RNA; RNA, Catalytic | 1997 |
Beta-thalassaemia in indigenous Belgians: an update.
Topics: Adenine; Amino Acid Substitution; Anemia; Anemia, Hypochromic; Belgium; Beta-Globulins; beta-Thalassemia; Blotting, Southern; Codon; Cystine; Gene Deletion; Guanine; Heterozygote; Humans; Immunoblotting; Mutation; Nucleic Acid Hybridization; Oligonucleotide Probes; Risk Factors; Sequence Analysis, DNA; Thymine | 1997 |
Structural studies on tRNA acceptor stem microhelices: exchange of the discriminator base A73 for G in human tRNALeu switches the acceptor specificity from leucine to serine possibly by decreasing the stability of the terminal G1-C72 base pair.
Topics: Adenine; Base Composition; Cytosine; Guanine; Humans; Leucine; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Protons; RNA, Transfer, Leu; RNA, Transfer, Ser; Serine; Serine-tRNA Ligase; Temperature; Ultraviolet Rays | 1997 |
Relative stability of triplexes containing different numbers of T.AT and C+.GC triplets.
Topics: Adenine; Base Composition; Base Sequence; Cytosine; Deoxyribonuclease I; DNA; DNA Footprinting; Guanine; Molecular Sequence Data; Nucleic Acid Conformation; Thymine | 1997 |
Expansion of the cellular content of ribonucleoside triphosphates induces cell shrinkage and KCl loss in Ehrlich ascites tumor cells and in Chinese hamster ovary cells.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Carcinoma, Ehrlich Tumor; Chloride Channels; Chlorides; CHO Cells; Cricetinae; Guanine; Guanosine; Guanosine Triphosphate; Kinetics; Mice; Potassium Channels; Potassium Chloride; Purines; Ribonucleotides; Tumor Cells, Cultured | 1997 |
Targeted deletion of alkylpurine-DNA-N-glycosylase in mice eliminates repair of 1,N6-ethenoadenine and hypoxanthine but not of 3,N4-ethenocytosine or 8-oxoguanine.
Topics: Adenine; Animals; Cell-Free System; Cytosine; DNA Glycosylases; DNA Repair; Guanine; Hydrolysis; Hypoxanthine; Mice; Mice, Inbred BALB C; Mice, Knockout; N-Glycosyl Hydrolases; Recombinant Proteins; Substrate Specificity | 1997 |
An alteration in the structure of the minor groove of duplex DNA induced by the formation of an intermolecular d(GA)n:d(GA)n.d(TC)n triplex.
Topics: Adenine; Base Composition; Cations, Divalent; Cytosine; DNA; DNA Footprinting; DNA Methylation; Guanine; Hydrogen-Ion Concentration; Magnesium; Nucleic Acid Conformation; Nucleic Acid Heteroduplexes; Purines; Pyrimidines; Thymine; Water | 1997 |
In vivo association of lamins with nucleic acids in Drosophila melanogaster.
Topics: Adenine; Animals; Bromodeoxyuridine; Cells, Cultured; Cross-Linking Reagents; Cytosine; DNA; Drosophila melanogaster; Guanine; Interphase; Lamins; Mitosis; Nuclear Proteins; Nucleic Acid Denaturation; Photochemistry; Precipitin Tests; RNA; Thymine | 1998 |
Ni2+-binding RNA motifs with an asymmetric purine-rich internal loop and a G-A base pair.
Topics: Adenine; Base Composition; Base Sequence; Binding Sites; Guanine; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Nickel; Nucleic Acid Conformation; Protons; Purines; RNA; Ultraviolet Rays | 1997 |
Beyond the wobble: the rule of conjugates.
Topics: Adenine; Cytosine; Genetic Code; Guanine; Protein Biosynthesis; Uracil | 1997 |
Clinical, physiological, and histological features in a kindred with the T3271C melas mutation.
Topics: Adenine; Adult; Biopsy, Needle; Child, Preschool; Cytosine; DNA; DNA, Mitochondrial; Female; Forearm; Guanine; Humans; Infant; Ischemia; Male; MELAS Syndrome; Middle Aged; Mitochondria, Muscle; Muscle, Skeletal; North America; Pedigree; Point Mutation; RNA; RNA, Mitochondrial; Thymine | 1998 |
Structure-based redesign of corepressor specificity of the Escherichia coli purine repressor by substitution of residue 190.
Topics: Adenine; Alanine; Arginine; Bacterial Proteins; Crystallography, X-Ray; Enzyme Repression; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Glutamine; Guanine; Hypoxanthine; Ligands; Mutagenesis, Site-Directed; Protein Conformation; Protein Engineering; Purines; Repressor Proteins | 1998 |
Isoleucylation properties of native human mitochondrial tRNAIle and tRNAIle transcripts. Implications for cardiomyopathy-related point mutations (4269, 4317) in the tRNAIle gene.
Topics: Adenine; Base Sequence; Female; Guanine; Humans; Isoleucine-tRNA Ligase; Kinetics; Mitochondria; Mitochondrial Myopathies; Molecular Sequence Data; Placenta; Point Mutation; Pregnancy; RNA; RNA, Mitochondrial; RNA, Transfer, Ile; Transcription, Genetic | 1998 |
A G-->A transition creates a branch point sequence and activation of a cryptic exon, resulting in the hereditary disorder neurofibromatosis 2.
Topics: Adenine; Adult; Aged; Alternative Splicing; Amino Acid Sequence; Base Sequence; Cloning, Molecular; DNA, Complementary; Exons; Female; Genes, Neurofibromatosis 2; Guanine; Humans; Introns; Male; Membrane Proteins; Middle Aged; Molecular Sequence Data; Neurofibromatosis 2; Neurofibromin 2; Pedigree; Point Mutation; RNA, Messenger | 1998 |
DNA mismatch repair catalyzed by extracts of mitotic, postmitotic, and senescent Drosophila tissues and involvement of mei-9 gene function for full activity.
Topics: Adenine; Animals; Catalysis; Cellular Senescence; Cytosine; DNA Repair; DNA-Binding Proteins; Drosophila melanogaster; Drosophila Proteins; Female; Guanine; HeLa Cells; Humans; Insect Proteins; Male; Mitosis; Mutation; Nickel; Nuclear Proteins; Nucleic Acid Heteroduplexes; Thymine; Tissue Extracts | 1998 |
Base-specific sequences that bias somatic hypermutation deduced by analysis of out-of-frame human IgVH genes.
Topics: Adenine; Base Composition; Cytosine; Genes, Immunoglobulin; Guanine; Humans; Immunoglobulin Heavy Chains; Immunoglobulin Variable Region; Molecular Sequence Data; Mutation; Reading Frames; Regulatory Sequences, Nucleic Acid | 1998 |
Changes in chromosomal localization of heterochromatin-binding proteins during the cell cycle in Drosophila.
Topics: Adenine; Animals; Base Sequence; Chromosome Mapping; Chromosomes; DNA, Satellite; Drosophila melanogaster; Gene Expression Regulation; Genes, Insect; Guanine; Heterochromatin; In Situ Hybridization, Fluorescence; Interphase; Metaphase; Mitosis; Molecular Sequence Data; Mutagenesis, Insertional; Repetitive Sequences, Nucleic Acid | 1998 |
Alteration of the fatty acid substrate specificity of lysophosphatidate acyltransferase by site-directed mutagenesis.
Topics: 1-Acylglycerol-3-Phosphate O-Acyltransferase; Acyltransferases; Adenine; Alanine; Amino Acid Substitution; Bacterial Proteins; Binding, Competitive; Dyneins; Escherichia coli; Escherichia coli Proteins; Fatty Acids; Fungal Proteins; Guanine; Leucine; Mutagenesis, Site-Directed; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Substrate Specificity; Temperature; Threonine; Transformation, Bacterial | 1998 |
Cr(III)-mediated crosslinks of glutathione or amino acids to the DNA phosphate backbone are mutagenic in human cells.
Topics: Adenine; Base Composition; Base Sequence; Chromium; Cross-Linking Reagents; Cytosine; DNA Adducts; Escherichia coli; Fibroblasts; Glutathione; Guanine; Humans; Kinetics; Molecular Sequence Data; Mutagenesis; Plasmids; Point Mutation; Polymerase Chain Reaction; Thymine; Transfection | 1998 |
Comparable impact of mutational and selective influences in shaping the expressed repertoire of peripheral IgM+/CD5- and IgM+/CD5+ B cells.
Topics: Adenine; Adult; B-Lymphocyte Subsets; CD5 Antigens; Codon; Cytosine; DNA Mutational Analysis; Gene Rearrangement, B-Lymphocyte, Heavy Chain; Guanine; Humans; Immunoglobulin Heavy Chains; Immunoglobulin Joining Region; Immunoglobulin M; Immunoglobulin Variable Region; Male; Middle Aged; Molecular Sequence Data; Mutation; Purine Nucleotides; Serine; Statistics, Nonparametric | 1998 |
The microsatellite sequence (CT)n x (GA)n promotes stable chromosomal integration of large tandem arrays of functional human U2 small nuclear RNA genes.
Topics: Adenine; Cytosine; Dinucleotide Repeats; Guanine; Humans; Microsatellite Repeats; Recombination, Genetic; RNA, Small Nuclear; Thymidine; Transcription, Genetic; Tumor Cells, Cultured | 1998 |
Measurement of oxidative DNA damage by gas chromatography-mass spectrometry: ethanethiol prevents artifactual generation of oxidized DNA bases.
Topics: Adenine; Animals; Cattle; Cytosine; DNA; DNA Damage; Gas Chromatography-Mass Spectrometry; Guanine; Guanine Deaminase; Oxidation-Reduction; Pentoxyl; Sulfhydryl Compounds; Temperature | 1998 |
Statistical features of human exons and their flanking regions.
Topics: Adenine; Base Composition; Bayes Theorem; Codon; Confidence Intervals; Cytosine; Databases, Factual; Exons; Guanine; Humans; Introns; Reading Frames; Sequence Analysis, DNA; Thymine | 1998 |
Gel electrophoretic detection of 7,8-dihydro-8-oxoguanine and 7, 8-dihydro-8-oxoadenine via oxidation by Ir (IV).
Topics: Adenine; DNA Damage; DNA Primers; Electrophoresis, Polyacrylamide Gel; Guanine; Iridium; Oxidation-Reduction | 1998 |
The different mobility of complementary strands depends on the proportion AC/GT.
Topics: Adenine; Alleles; Base Composition; Bias; Cytosine; DNA Fingerprinting; DNA Fragmentation; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Guanine; Humans; Linear Models; Microsatellite Repeats; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Reproducibility of Results; Thymine | 1998 |
Selection and characterisation of murine leukaemia L1210 cells with high-level resistance to the cytostatic activity of the acyclic nucleoside phosphonate 9-(2-phosphonylmethoxyethyl) adenine (PMEA).
Topics: Adenine; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antineoplastic Agents; Biological Transport; Biotransformation; Cell Survival; Cyclic AMP; Drug Resistance, Neoplasm; Guanine; Kinetics; Leukemia L1210; Mice; Organophosphonates; Organophosphorus Compounds; Purine Nucleotides; Structure-Activity Relationship; Tumor Cells, Cultured | 1998 |
Recognition and interaction of small rings with the ricin A-chain binding site.
Topics: Adenine; Binding Sites; Enzyme Inhibitors; Formycins; Glucosidases; Guanine; Hydrogen Bonding; Ligands; Models, Chemical; Protein Binding; Pterins; Ricin; Substrate Specificity | 1998 |
Topical reversion at the HIS1 locus of Saccharomyces cerevisiae. A tale of three mutants.
Topics: Adenine; Genes, Fungal; Guanine; Mutation; Saccharomyces cerevisiae; Thymine | 1998 |
The hemochromatosis 845 G-->A and 187 C-->G mutations: prevalence in non-Caucasian populations.
Topics: Adenine; Asian People; Australia; Cytosine; Gene Frequency; Guanine; Hemochromatosis; Histocompatibility Testing; Humans; Native Hawaiian or Other Pacific Islander; Point Mutation; Polynesia | 1998 |
Genotoxicity of purine acyclic nucleotide analogs.
Topics: Adenine; Animals; Antiviral Agents; Cell Line; Female; Guanine; Humans; Male; Molecular Structure; Mutagenicity Tests; Mutagens; Organophosphonates; Organophosphorus Compounds; Purines; Rats; Rats, Inbred BN; Rats, Inbred Lew; Tenofovir; Teratogens; Thioguanine | 1997 |
The electron affinities of the radicals formed by the loss of an aromatic hydrogen atom from adenine, guanine, cytosine, uracil, and thymine.
Topics: Adenine; Cytosine; Electrochemistry; Free Radicals; Guanine; Hydrogen; Mass Spectrometry; Purines; Pyrimidines; Thermodynamics; Thymine; Uracil | 1998 |
Dissection of the sequence specificity of the Holliday junction endonuclease CCE1.
Topics: Adenine; Base Composition; Base Sequence; Cytosine; Endodeoxyribonucleases; Guanine; Holliday Junction Resolvases; Hydrolysis; Protein Conformation; Recombination, Genetic; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Thymine | 1998 |
The A/G polymorphism in the -78 position of the apolipoprotein A-I promoter does not have a direct effect on transcriptional efficiency.
Topics: Adenine; Apolipoprotein A-I; Guanine; Humans; Polymerase Chain Reaction; Polymorphism, Genetic; Promoter Regions, Genetic; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1998 |
Hypoxanthine, guanine, xanthine phosphoribosyltransferase activity in Cryptosporidium parvum.
Topics: Adenine; Animals; Autoradiography; Binding, Competitive; Cell Line; Cryptosporidium parvum; Dogs; Formates; Glycine; Guanine; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Pentosyltransferases; Spores; Xanthine | 1998 |
Antiparallel DNA duplex formation between alternating alpha d(GA)n and beta d(GA)n sequences.
Topics: Adenine; Base Composition; Circular Dichroism; Dinucleotide Repeats; DNA; Guanine; Hot Temperature; Nucleic Acid Conformation; Nucleic Acid Denaturation; Oligodeoxyribonucleotides | 1998 |
The pro-oxidant and antioxidant effects of vitamin C.
Topics: Adenine; Antioxidants; Ascorbic Acid; DNA; Guanine; Oxidants | 1998 |
Mutation in the tau gene in familial multiple system tauopathy with presenile dementia.
Topics: Adenine; Alternative Splicing; Base Sequence; Chromosomes, Human, Pair 17; Dementia; Exons; Female; Guanine; Humans; Introns; Male; Molecular Sequence Data; Nucleic Acid Conformation; Pedigree; Point Mutation; Sequence Analysis, DNA; tau Proteins | 1998 |
Genetic polymorphisms adjacent to the CAG repeat influence clinical features at onset in Huntington's disease.
Topics: Adenine; Adult; Age of Onset; Aged; Alleles; Cytosine; Gene Deletion; Genotype; Guanine; Humans; Huntington Disease; Middle Aged; Phenotype; Point Mutation; Polymorphism, Genetic; Trinucleotide Repeats | 1998 |
Oxidative damage to proteins, lipids, and DNA in cortical brain regions from patients with dementia with Lewy bodies.
Topics: Adenine; Aged; Aged, 80 and over; Alzheimer Disease; Brain Chemistry; Cerebral Cortex; Cytosine; DNA; Guanine; Humans; Hydantoins; Hypoxanthine; Lewy Bodies; Lipid Peroxidation; Middle Aged; Nerve Tissue Proteins; Oxidation-Reduction; Oxidative Stress; Thymine; Uracil; Xanthine | 1998 |
Nearest-neighbor thermodynamics of internal A.C mismatches in DNA: sequence dependence and pH effects.
Topics: Adenine; Base Composition; Base Sequence; Cytosine; DNA; DNA Repair; DNA Replication; Guanine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Models, Chemical; Nucleic Acid Conformation; Nucleic Acid Heteroduplexes; Thermodynamics; Thymine | 1998 |
Hydrophobicities of the nucleic acid bases: distribution coefficients from water to cyclohexane.
Topics: Adenine; Alkylation; Cyclohexanes; Cytosine; Guanine; Models, Chemical; Solvents; Thymine; Water | 1998 |
Circular dichroism of DNA frayed wires.
Topics: Adenine; Base Composition; Circular Dichroism; DNA; Electrophoresis, Polyacrylamide Gel; Guanine; Models, Molecular; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Solubility; Solutions; Thermodynamics | 1998 |
Severe 5-fluorouracil toxicity caused by reduced dihydropyrimidine dehydrogenase activity due to heterozygosity for a G-->A point mutation.
Topics: Adenine; Antimetabolites, Antineoplastic; Breast Neoplasms; Cells, Cultured; Dihydrouracil Dehydrogenase (NADP); Female; Fluorouracil; Guanine; Heterozygote; Humans; Leukocytes, Mononuclear; Middle Aged; Oxidation-Reduction; Oxidoreductases; Point Mutation; Polymerase Chain Reaction; Transcription, Genetic | 1998 |
Structure of d(GT)n.d(GA)n sequences: formation of parallel stranded duplex DNA.
Topics: Adenine; Base Composition; Base Sequence; Circular Dichroism; DNA; Electrophoresis, Polyacrylamide Gel; Guanine; Nucleic Acid Conformation; Nucleic Acid Heteroduplexes; Oligodeoxyribonucleotides; Spectrophotometry, Ultraviolet; Thermodynamics; Thymine | 1998 |
The base contents of A, C, G or U for the three codon positions and the total coding sequences show positive correlation.
Topics: Adenine; Base Composition; Codon; Computer Graphics; Cytosine; Guanine; Models, Molecular; Models, Statistical; Uracil | 1998 |
Oxidation of DNA bases, deoxyribonucleosides and homopolymers by peroxyl radicals.
Topics: Adenine; Amidines; Base Pairing; Cytosine; Deoxyribonucleosides; DNA; Free Radicals; Guanine; Mass Spectrometry; Oxidation-Reduction; Purines; Pyrimidines; Reactive Oxygen Species; Thymine | 1998 |
Prothrombin gene 20210 G-A mutation in Turkish patients with thrombosis.
Topics: Adenine; Adolescent; Adult; Alleles; Child; Female; Gene Frequency; Guanine; Humans; Male; Point Mutation; Prothrombin; Thrombosis; Turkey | 1998 |
Single-turnover and pre-steady-state kinetics of the reaction of the adenine glycosylase MutY with mismatch-containing DNA substrates.
Topics: Adenine; Base Pair Mismatch; Base Pairing; Binding Sites; Deoxyguanosine; DNA; DNA Glycosylases; DNA Repair; Guanine; Kinetics; N-Glycosyl Hydrolases; Oligonucleotides; Substrate Specificity; Titrimetry | 1998 |
Hepatitis C virus infection associated with human hepatocellular carcinoma: lack of correlation with p53 abnormalities in Caucasian patients.
Topics: Adenine; Aged; Carcinoma, Hepatocellular; Codon; Cohort Studies; DNA, Viral; Exons; Female; Genes, p53; Genome, Viral; Genotype; Guanine; Hepacivirus; Hepatitis B; Hepatitis C; Humans; Liver Neoplasms; Male; Middle Aged; Mutation; Polymorphism, Single-Stranded Conformational; RNA, Viral; Sequence Analysis, DNA; Thymine; White People | 1998 |
Increased nuclear DNA oxidation in the brain in Alzheimer's disease.
Topics: Adenine; Aged; Aged, 80 and over; Alzheimer Disease; Brain; Cadaver; Cell Nucleus; Cytosine; DNA; Gas Chromatography-Mass Spectrometry; Guanine; Humans; Oxidation-Reduction; Pyrimidines; Reference Values; Tissue Distribution | 1998 |
Heterogeneous repair of N-methylpurines at the nucleotide level in normal human cells.
Topics: Adenine; Base Sequence; Chromatin; DNA Adducts; DNA Damage; DNA Footprinting; DNA Glycosylases; DNA Repair; Exons; Fibroblasts; Guanine; Half-Life; Humans; Male; Molecular Sequence Data; N-Glycosyl Hydrolases; Phosphoglycerate Kinase; Promoter Regions, Genetic; Sulfuric Acid Esters | 1998 |
Structure-function relationships in the hammerhead ribozyme probed by base rescue.
Topics: Adenine; Base Sequence; Binding Sites; Catalytic Domain; Crystallization; Guanine; Hydrogen Bonding; Kinetics; Models, Biological; Mutagenesis, Site-Directed; Nucleic Acid Conformation; RNA, Catalytic; Structure-Activity Relationship; Thermodynamics | 1998 |
Tobacco BY-2 cells excise both 3-methyladenine and 7-methylguanine from methylated DNA.
Topics: Adenine; Animals; Cattle; Cell Line; Chromatography, High Pressure Liquid; DNA; DNA Glycosylases; DNA Methylation; Guanine; Methyl Methanesulfonate; Methylnitrosourea; Mutagens; N-Glycosyl Hydrolases; Nicotiana; Plants, Toxic | 1998 |
FTIR and UV spectroscopy of parallel-stranded DNAs with mixed A*T/G*C sequences and their A*T/I*C analogues.
Topics: Adenine; Base Composition; Base Sequence; Cytosine; DNA; Guanine; Hot Temperature; Hydrogen Bonding; Hypoxanthine; Inosine; Models, Molecular; Nucleic Acid Denaturation; Nucleic Acid Heteroduplexes; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Thymine | 1998 |
Triple helix formation by (G,A)-containing oligonucleotides: asymmetric sequence effect.
Topics: Adenine; Base Pair Mismatch; Base Sequence; Circular Dichroism; DNA; Electrophoresis, Polyacrylamide Gel; Guanine; Nucleic Acid Conformation; Nucleic Acid Denaturation; Nucleic Acid Heteroduplexes; Oligodeoxyribonucleotides; Spectrophotometry, Ultraviolet; Temperature; Trinucleotide Repeats | 1998 |
MutY catalytic core, mutant and bound adenine structures define specificity for DNA repair enzyme superfamily.
Topics: Adenine; Amino Acid Sequence; Base Pair Mismatch; Catalytic Domain; Crystallography, X-Ray; DNA; DNA Glycosylases; DNA Repair; Guanine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; N-Glycosyl Hydrolases; Protein Conformation; Substrate Specificity | 1998 |
Determination of oxidative DNA base damage by gas chromatography-mass spectrometry. Effect of derivatization conditions on artifactual formation of certain base oxidation products.
Topics: Adenine; Animals; Artifacts; Cytosine; DNA; DNA Damage; Gas Chromatography-Mass Spectrometry; Guanine; Hydantoins; Hydrolysis; Nitrogen; Oxidation-Reduction; Pentoxyl; Purines; Pyrimidines; Temperature; Time Factors | 1998 |
Dimerization of the guanine-adenine repeat strands of DNA.
Topics: Acids; Adenine; Circular Dichroism; Dimerization; Dinucleotide Repeats; DNA, Single-Stranded; Ethanol; Guanine; Hot Temperature; Nucleic Acid Conformation; Nucleic Acid Denaturation; Salts | 1999 |
Endothelial cell compatibility of clarithromycin for intravenous use.
Topics: Adenine; Adenosine Triphosphate; Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Clarithromycin; Dose-Response Relationship, Drug; Endothelium, Vascular; Guanine; Humans; In Vitro Techniques; Infusions, Intravenous; Rabbits; Statistics, Nonparametric; Umbilical Veins | 1998 |
Electron transfer between bases in double helical DNA.
Topics: 2-Aminopurine; Adenine; Base Pairing; DNA; Electrons; Guanine; Hydrogen Bonding; Kinetics; Light; Nucleic Acid Conformation; Oxidation-Reduction; Spectrometry, Fluorescence; Thermodynamics | 1999 |
Triple helix formation: binding avidity of acridine-conjugated AG motif third strands containing natural, modified and surrogate bases opposed to pyrimidine interruptions in a polypurine target.
Topics: Acridines; Adenine; Gene Expression Regulation; Genetic Techniques; Guanine; Intercalating Agents; Kinetics; Models, Molecular; Nucleic Acid Conformation; Oligonucleotides; Purines; Pyrimidines; Pyrroles | 1999 |
Effect of base analog substitutions in the specific GATC site on binding and methylation of oligonucleotide duplexes by the bacteriophage T4 Dam DNA-[N6-adenine] methyltransferase.
Topics: 2-Aminopurine; Adenine; Bacteriophage T4; Binding Sites; DNA Methylation; Guanine; Kinetics; Mutagenesis, Site-Directed; Oligonucleotides; Purines; Site-Specific DNA-Methyltransferase (Adenine-Specific); Viral Proteins | 1999 |
Nuclease resistant hammerhead motif: from '5-ribo' to '3-ribo' model.
Topics: Adenine; Catalysis; Chromatography, High Pressure Liquid; Guanine; Models, Biological; Mutagenesis; Oligoribonucleotides; Organophosphorus Compounds; RNA, Catalytic | 1999 |
Nitrogen-15 chemical shifts in AT (adenine-thymine) and CG (cytosine-guanine) nucleic acid base pairs.
Topics: Adenine; Base Pairing; Computer Simulation; Crystallography, X-Ray; Cytosine; Guanine; Magnetic Resonance Spectroscopy; Models, Statistical; Nitrogen Isotopes; Thymine | 1998 |
The major, N2-dG adduct of (+)-anti-B[a]PDE induces G-->A mutations in a 5'-AGA-3' sequence context.
Topics: Adenine; Amino Acid Substitution; Benzo(a)pyrene; Cells, Cultured; Chromatography, High Pressure Liquid; Guanine; Mutagens; Mutation, Missense; Oligonucleotides; Plasmids; SOS Response, Genetics | 1999 |
In vitro reactions of butadiene monoxide with single- and double-stranded DNA: characterization and quantitation of several purine and pyrimidine adducts.
Topics: Adenine; Alkylation; Deoxyadenosines; Deoxyguanosine; Deoxyuridine; DNA; DNA Adducts; DNA, Single-Stranded; Dose-Response Relationship, Drug; Epoxy Compounds; Guanine; Mutagens; Purines; Pyrimidines | 1999 |
A G to A transition at the last nucleotide of exon 6 of the gamma c gene (868G-->A) may result in either a splice or missense mutation in patients with X-linked severe combined immunodeficiency.
Topics: Adenine; Alternative Splicing; Base Sequence; Exons; Frameshift Mutation; Guanine; Humans; Infant; Male; Molecular Sequence Data; Mutation, Missense; Pedigree; Reverse Transcriptase Polymerase Chain Reaction; Severe Combined Immunodeficiency | 1999 |
C8-Arylguanine and C8-aryladenine formation in calf thymus DNA from arenediazonium ions.
Topics: Adenine; Animals; Cattle; Chromatography, High Pressure Liquid; Diazonium Compounds; DNA Adducts; Electron Spin Resonance Spectroscopy; Free Radicals; Guanine; Hot Temperature; Hydrogen-Ion Concentration; Thymus Gland | 1999 |
RNA folding and misfolding of the hammerhead ribozyme.
Topics: Adenine; Deoxyguanosine; Energy Transfer; Enzyme Activation; Fluorescence Polarization; Guanine; Hydrolysis; Magnesium; Mutagenesis, Site-Directed; Nucleic Acid Conformation; Photochemistry; RNA, Catalytic; Spectrometry, Fluorescence; Uracil | 1999 |
Acyclic nucleotide analogues suppress growth and induce apoptosis in human leukemia cell lines.
Topics: Adenine; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Division; DNA, Neoplasm; Drug Screening Assays, Antitumor; Guanine; HL-60 Cells; Humans; Leukemia, Myeloid; Organophosphorus Compounds; Tumor Cells, Cultured | 1999 |
Association between seasonal affective disorder and the 5-HT2A promoter polymorphism, -1438G/A.
Topics: Adenine; Adult; Alleles; Carrier Proteins; Female; Gene Frequency; Genetic Variation; Guanine; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Point Mutation; Polymorphism, Genetic; Promoter Regions, Genetic; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Reference Values; Seasonal Affective Disorder; Serotonin Plasma Membrane Transport Proteins | 1999 |
Reactivity of potassium permanganate and tetraethylammonium chloride with mismatched bases and a simple mutation detection protocol.
Topics: Adenine; Animals; Base Pair Mismatch; Cytidine; Guanine; Mice; Mutagenesis; Osmium Tetroxide; Potassium Permanganate; Tetraethylammonium; Thymine | 1999 |
Coagulation factors II, V, VII, and X, prothrombin gene 20210G-->A transition, and factor V Leiden in coronary artery disease: high factor V clotting activity is an independent risk factor for myocardial infarction.
Topics: Activated Protein C Resistance; Adenine; Adult; Aged; Case-Control Studies; Coronary Disease; Factor V; Factor VII; Factor X; Female; Guanine; Humans; Male; Middle Aged; Myocardial Infarction; Point Mutation; Prothrombin; Risk Factors; Switzerland | 1999 |
Mutations in promoter region of thrombomodulin and venous thromboembolic disease.
Topics: Adenine; Adult; Case-Control Studies; Female; France; Genetic Testing; Guanine; Humans; Male; Middle Aged; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Promoter Regions, Genetic; Thromboembolism; Thrombomodulin; Venous Thrombosis | 1999 |
Different adaptations of the same peptide motif for tRNA functional contacts by closely homologous tRNA synthetases.
Topics: Acylation; Adenine; Escherichia coli; Guanine; Humans; Kinetics; Lysine-tRNA Ligase; Models, Molecular; Mutagenesis, Site-Directed; Peptides; RNA, Transfer, Lys; Sequence Homology, Amino Acid; Substrate Specificity | 1999 |
Modulation of the toxic and mutagenic effects induced by methyl methanesulfonate in Chinese hamster ovary cells by overexpression of the rat N-alkylpurine-DNA glycosylase.
Topics: Adenine; Alkylating Agents; Animals; Base Pair Mismatch; CHO Cells; Cricetinae; Cricetulus; DNA Damage; DNA Glycosylases; DNA Ligases; DNA Methylation; DNA Repair; Enzyme Induction; Frameshift Mutation; Guanine; Hypoxanthine Phosphoribosyltransferase; Methyl Methanesulfonate; Mutagenesis; Mutagens; N-Glycosyl Hydrolases; Rats; Recombinant Fusion Proteins; Transfection | 1999 |
Parallel and antiparallel triple helices with G, A-containing third strands.
Topics: Adenine; Animals; DNA, Viral; Friend murine leukemia virus; Guanine; Mice; Oligodeoxyribonucleotides; Purines | 1999 |
A novel mutation (8342G-->A) in the mitochondrial tRNA(Lys) gene associated with progressive external ophthalmoplegia and myoclonus.
Topics: Adenine; Adult; Autoanalysis; Base Sequence; Epilepsies, Myoclonic; Female; Guanine; Humans; Molecular Sequence Data; Nucleic Acid Conformation; Ophthalmoplegia, Chronic Progressive External; Pedigree; Point Mutation; RNA; RNA, Mitochondrial; RNA, Transfer, Lys | 1999 |
Classification of organic molecules to obtain electron affinities from half-wave reduction potentials: cytosine, uracil, thymine, guanine and adenine.
Topics: Adenine; Algorithms; Cytosine; Electrons; Guanine; Organic Chemicals; Oxidation-Reduction; Riboflavin; Solvents; Thymine; Uracil; Vitamin A; Vitamin E | 1999 |
The prebiotic synthesis of modified purines and their potential role in the RNA world.
Topics: Adenine; Adenosine; Amines; Amino Acids; Guanine; Hydrogen-Ion Concentration; Hydrolysis; Hypoxanthine; Hypoxanthines; Purines; RNA; Temperature | 1999 |
The type of DNA glycosylase determines the base excision repair pathway in mammalian cells.
Topics: Adenine; Animals; Base Sequence; Cells, Cultured; DNA Glycosylases; DNA Repair; Guanine; HeLa Cells; Humans; Hypoxanthine; Mice; N-Glycosyl Hydrolases | 1999 |
Hb Siriraj: a G-->A substitution at codon 7 of the beta-globin chain creates an MboII cutting site.
Topics: Adenine; Amino Acid Substitution; Codon; Globins; Guanine; Hemoglobins, Abnormal; Humans | 1999 |
The C-terminal domain of the adenine-DNA glycosylase MutY confers specificity for 8-oxoguanine.adenine mispairs and may have evolved from MutT, an 8-oxo-dGTPase.
Topics: Adenine; Amino Acid Sequence; Base Pair Mismatch; DNA Glycosylases; DNA Repair; DNA, Bacterial; Escherichia coli; Guanine; Humans; Kinetics; Molecular Sequence Data; N-Glycosyl Hydrolases; Peptide Fragments; Protein Structure, Tertiary; Sequence Analysis; Sequence Homology, Amino Acid | 1999 |
Sensitivity of L-(-)2,3-dideoxythiacytidine resistant hepatitis B virus to other antiviral nucleoside analogues.
Topics: Acyclovir; Adenine; Antiviral Agents; Arabinofuranosyluracil; DNA-Directed DNA Polymerase; Drug Resistance, Microbial; Drug Resistance, Multiple; Guanine; Hepatitis B virus; Lamivudine; Microbial Sensitivity Tests; Mutation; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Zalcitabine | 1999 |
Late infantile neuronal ceroid lipofuscinosis is due to splicing mutations in the CLN2 gene.
Topics: Adenine; Aminopeptidases; Child; Child, Preschool; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Endopeptidases; Female; Frameshift Mutation; Gene Frequency; Guanine; Humans; Neuronal Ceroid-Lipofuscinoses; Peptide Hydrolases; RNA Splicing; RNA, Messenger; Serine Proteases; Tripeptidyl-Peptidase 1 | 1999 |
DNA methylation by tert-butyl hydroperoxide-iron (II): a role for the transition metal ion in the production of DNA base adducts.
Topics: Adenine; Animals; Cattle; Chelating Agents; Copper; DNA Adducts; DNA Methylation; Electron Spin Resonance Spectroscopy; Free Radicals; Guanine; Iron; Molecular Structure; tert-Butylhydroperoxide | 1999 |
Polybenzamide mustards: structure-activity relationships for DNA sequence-specific alkylation.
Topics: Adenine; Alkylation; Animals; Antineoplastic Agents, Alkylating; Benzamides; Cattle; DNA; DNA Footprinting; DNA, Bacterial; Escherichia coli; Guanine; In Situ Nick-End Labeling; Nitrogen Mustard Compounds; Plasmids; Structure-Activity Relationship | 1999 |
Pigmentary retinal dystrophy and the syndrome of maternally inherited diabetes and deafness caused by the mitochondrial DNA 3243 tRNA(Leu) A to G mutation.
Topics: Adenine; Adult; Aged; Aged, 80 and over; Deafness; Diabetes Mellitus, Type 2; DNA, Mitochondrial; Electrooculography; Electroretinography; Female; Fundus Oculi; Guanine; Humans; Male; Middle Aged; Pedigree; Photoreceptor Cells, Vertebrate; Pigment Epithelium of Eye; Point Mutation; Retinitis Pigmentosa; RNA, Transfer, Leu; Syndrome; Visual Acuity | 1999 |
Guanine-adenine ligation-mediated polymerase chain reaction in vivo footprinting.
Topics: Adenine; Animals; Base Sequence; Binding Sites; Cells, Cultured; DNA; DNA Footprinting; DNA Methylation; DNA Primers; DNA-Binding Proteins; Erythroid-Specific DNA-Binding Factors; GATA1 Transcription Factor; Guanine; Humans; Hybrid Cells; Indicators and Reagents; Mice; Polymerase Chain Reaction; Transcription Factors; Tumor Cells, Cultured | 1999 |
Susceptibility of lamivudine-resistant hepatitis B virus to other reverse transcriptase inhibitors.
Topics: Acyclovir; Adenine; Carcinoma, Hepatocellular; Drug Resistance, Microbial; Guanine; Hepatitis B virus; Humans; Lamivudine; Mutagenesis, Site-Directed; Nevirapine; Organophosphonates; Reverse Transcriptase Inhibitors; Transfection; Tumor Cells, Cultured | 1999 |
The CAG repeat within the androgen receptor gene and benign prostatic hyperplasia.
Topics: Adenine; Cytosine; Guanine; Humans; Male; Prostatic Hyperplasia; Receptors, Androgen; Trinucleotide Repeats | 1999 |
Oxidative DNA base damage in cancerous tissues of patients undergoing brachytherapy.
Topics: Adenine; Brachytherapy; Cytosine; DNA Damage; DNA, Neoplasm; Female; Gas Chromatography-Mass Spectrometry; Guanine; Humans; Oxidation-Reduction; Pyrimidines; Uracil; Uterine Cervical Neoplasms | 1998 |
9-(2-Phosphonylmethoxyethyl)-N6-cyclopropyl-2,6-diaminopurine (cpr-PMEDAP) as a prodrug of 9-(2-phosphonylmethoxyethyl)guanine (PMEG).
Topics: Adenine; Animals; Antineoplastic Agents; Antiviral Agents; Cell Division; Deamination; Dideoxynucleosides; Guanine; Humans; Organophosphorus Compounds; Prodrugs; Rats; Tumor Cells, Cultured | 1999 |
N6-cyclopropyl-PMEDAP: a novel derivative of 9-(2-phosphonylmethoxyethyl)-2,6-diaminopurine (PMEDAP) with distinct metabolic, antiproliferative, and differentiation-inducing properties.
Topics: Adenine; Adenosine Deaminase; Adenosine Triphosphate; AMP Deaminase; Animals; Antineoplastic Agents; Cell Cycle; Cell Differentiation; Cell Division; Deoxyadenine Nucleotides; Drug Interactions; Drug Screening Assays, Antitumor; Erythrocytes; Guanine; Humans; K562 Cells; Leukemia L1210; Mice; Organophosphonates; Organophosphorus Compounds; Pentostatin; Prodrugs; Rats; Tumor Cells, Cultured | 1999 |
TSH receptor gene mutations and familial gestational hyperthyroidism.
Topics: Adenine; Chorionic Gonadotropin; Codon; Female; Guanine; Humans; Hyperthyroidism; Mutation; Pregnancy; Pregnancy Complications; Receptors, Thyrotropin | 1999 |
Thermodynamics of unpaired terminal nucleotides on short RNA helixes correlates with stacking at helix termini in larger RNAs.
Topics: Adenine; Animals; Base Pair Mismatch; Base Pairing; Base Sequence; Crystallization; Crystallography, X-Ray; Databases, Factual; Guanine; Hydrogen Bonding; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Pyrimidinones; Ribonucleotides; RNA; Static Electricity; Thermodynamics | 1999 |
Purine quantification in digesta from ruminants by spectrophotometric and HPLC methods.
Topics: Adenine; Animals; Cattle; Chromatography, High Pressure Liquid; Escherichia coli; Gastrointestinal Contents; Guanine; Purines; Rumen; Spectrophotometry | 1999 |
Enzymatic repair of 5-formyluracil. I. Excision of 5-formyluracil site-specifically incorporated into oligonucleotide substrates by alka protein (Escherichia coli 3-methyladenine DNA glycosylase II).
Topics: Adenine; Base Pair Mismatch; DNA Damage; DNA Glycosylases; DNA Repair; Escherichia coli; Guanine; Kinetics; Magnetic Resonance Spectroscopy; Methylnitronitrosoguanidine; Molecular Structure; N-Glycosyl Hydrolases; Oligodeoxyribonucleotides; Pentoxyl; Substrate Specificity; Thymine; Uracil | 1999 |
Enzymatic repair of 5-formyluracil. II. Mismatch formation between 5-formyluracil and guanine during dna replication and its recognition by two proteins involved in base excision repair (AlkA) and mismatch repair (MutS).
Topics: Adenine; Adenosine Triphosphatases; Bacterial Proteins; Base Pair Mismatch; DNA Glycosylases; DNA Repair; DNA Replication; DNA-Binding Proteins; Escherichia coli Proteins; Guanine; Kinetics; MutS DNA Mismatch-Binding Protein; N-Glycosyl Hydrolases; Oligodeoxyribonucleotides; Thymine; Uracil | 1999 |
The effect of experimental conditions on the levels of oxidatively modified bases in DNA as measured by gas chromatography-mass spectrometry: how many modified bases are involved? Prepurification or not?
Topics: Adenine; Animals; Artifacts; Cattle; Cytosine; DNA; Gas Chromatography-Mass Spectrometry; Guanine; Hydrolysis; Nucleotides; Oxidation-Reduction; Pentoxyl; Trifluoroacetic Acid; Uracil | 1999 |
The cytotoxicity of DNA carboxymethylation and methylation by the model carboxymethylating agent azaserine in human cells.
Topics: Adenine; Alkylating Agents; Azaserine; Azo Compounds; Burkitt Lymphoma; Carcinogens; DNA Adducts; DNA Damage; DNA Methylation; Drug Resistance; Enzyme Induction; Genetic Complementation Test; Glycine; Guanine; Humans; Lymphocytes; Methylation; O(6)-Methylguanine-DNA Methyltransferase; Tumor Cells, Cultured; Xeroderma Pigmentosum | 1999 |
Differential subcellular localization of human MutY homolog (hMYH) and the functional activity of adenine:8-oxoguanine DNA glycosylase.
Topics: Adenine; Alternative Splicing; Animals; Base Pair Mismatch; Biological Transport; Catalysis; Cell Nucleus; COS Cells; DNA Glycosylases; DNA Repair; DNA-Formamidopyrimidine Glycosylase; Escherichia coli; Escherichia coli Proteins; Exons; Guanine; Humans; Isoenzymes; Molecular Sequence Data; N-Glycosyl Hydrolases; Phenotype; Recombinant Fusion Proteins; RNA, Messenger; Sequence Homology, Amino Acid; Suppression, Genetic; Thymine | 1999 |
Mitochondrial maculopathy: geographic atrophy of the macula in the MELAS associated A to G 3243 mitochondrial DNA point mutation.
Topics: Adenine; Atrophy; Deafness; DNA, Mitochondrial; Electroretinography; Female; Guanine; Humans; Macula Lutea; Male; MELAS Syndrome; Middle Aged; Ophthalmoplegia; Pigment Epithelium of Eye; Point Mutation; Retinal Diseases | 1999 |
The p22 phox A640G gene polymorphism but not the C242T gene variation is associated with coronary heart disease in younger individuals.
Topics: Adenine; Angiotensinogen; Apolipoprotein A-I; Apolipoproteins B; Aryldialkylphosphatase; Coronary Angiography; Coronary Disease; Cytosine; Esterases; Gene Deletion; Genetic Variation; Guanine; Humans; Lipoprotein(a); Male; Membrane Transport Proteins; Middle Aged; NADPH Dehydrogenase; NADPH Oxidases; Phosphoproteins; Polymorphism, Genetic; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Risk Factors; Thymidine | 1999 |
Expression of size-polymorphic androgen receptor (AR) gene in ovarian endometriosis according to the number of cytosine, adenine, and guanine (CAG) repeats in AR alleles.
Topics: Adenine; Adult; Cytosine; Endometriosis; Female; Guanine; Heterozygote; Homozygote; Humans; Ovarian Diseases; Polymorphism, Genetic; Receptors, Androgen; Trinucleotide Repeats | 1999 |
Two single nucleotide polymorphisms of the hSNF5/INI1 gene.
Topics: Adenine; Chromosomal Proteins, Non-Histone; Chromosome Mapping; Chromosomes, Human, Pair 22; DNA-Binding Proteins; Exons; Genes, Tumor Suppressor; Guanine; Humans; Point Mutation; Polymorphism, Genetic; Rhabdoid Tumor; SMARCB1 Protein; Transcription Factors | 1999 |
The effect of the chain length of polynucleotides on their binding with platinum complexes.
Topics: Adenine; Cisplatin; Cytosine; DNA; DNA Adducts; Guanine; Isotopes; Kinetics; Magnetic Resonance Spectroscopy; Platinum; Polynucleotides; Structure-Activity Relationship | 1999 |
MSH2 and MSH6 are required for removal of adenine misincorporated opposite 8-oxo-guanine in S. cerevisiae.
Topics: Adenine; Base Pair Mismatch; DNA Damage; DNA Repair; DNA-Binding Proteins; Fungal Proteins; Guanine; Models, Genetic; Mutagenesis; MutS Homolog 2 Protein; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 1999 |
Correlation of deformability at a tRNA recognition site and aminoacylation specificity.
Topics: Acylation; Adenine; Base Pairing; Blotting, Western; Catalysis; Cytosine; Escherichia coli; Guanine; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Mutagenesis; Nucleic Acid Conformation; Protein Biosynthesis; RNA; RNA, Transfer, Ala; Uracil | 1999 |
DNA triple helix formation at target sites containing several pyrimidine interruptions: stabilization by protonated cytosine or 5-(1-propargylamino)dU.
Topics: Adenine; Cytosine; Deoxyribonuclease I; Deoxyuridine; DNA; DNA Footprinting; Guanine; Macromolecular Substances; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Protons; Pyrimidine Nucleotides; Thymine | 1999 |
1H, 13C and 15N resonance assignments of the C-terminal domain of MutY: an adenine glycosylase active on G:A mismatches.
Topics: Adenine; DNA Glycosylases; DNA Repair; Escherichia coli; Guanine; Magnetic Resonance Spectroscopy; N-Glycosyl Hydrolases | 1999 |
Systematic mutagenesis of TCR complementarity-determining region 3 residues: a single conservative substitution dramatically improves response to both multiple HLA-DR alleles and peptide variants.
Topics: Adenine; Alleles; Amino Acid Sequence; Amino Acid Substitution; Clone Cells; Conserved Sequence; Gene Rearrangement, beta-Chain T-Cell Antigen Receptor; Genes, Dominant; Genes, T-Cell Receptor alpha; Genes, T-Cell Receptor beta; Guanine; HLA-DR Antigens; Humans; Jurkat Cells; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptides; Point Mutation; Receptors, Antigen, T-Cell, alpha-beta; Recombinant Fusion Proteins | 1999 |
Resistance to thyroid hormone caused by a new mutation (V336M) in the thyroid hormone receptor beta gene.
Topics: Adenine; Adult; Chromosomes, Human, Pair 3; Female; Gestational Age; Guanine; Heterozygote; Humans; Infant; Infant, Newborn; Infant, Premature; Male; Mutation; Receptors, Thyroid Hormone; Sequence Analysis, DNA; Thyroid Hormone Resistance Syndrome; Thyrotropin; Triiodothyronine | 1999 |
9-(2-phosphonylmethoxyethyl)-N6-cyclopropyl-2,6-diaminopurine: a novel prodrug of 9-(2-phosphonylmethoxyethyl)guanine with improved antitumor efficacy and selectivity in choriocarcinoma-bearing rats.
Topics: Adenine; Animals; Antineoplastic Agents; Choriocarcinoma; Female; Guanine; Male; Organophosphonates; Organophosphorus Compounds; Pregnancy; Prodrugs; Rats; Tumor Cells, Cultured; Uterine Neoplasms | 1999 |
9-(2-phosphonylmethoxyethyl) derivatives of purine nucleotide analogs: A comparison of their metabolism and interaction with cellular DNA synthesis.
Topics: Adenine; Antineoplastic Agents; Deoxyadenine Nucleotides; DNA; DNA Polymerase I; DNA Polymerase II; DNA Polymerase III; Guanine; Humans; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Organophosphorus Compounds; Tumor Cells, Cultured | 1999 |
Thermodynamics of single mismatches in RNA duplexes.
Topics: Adenine; Base Pair Mismatch; Base Pairing; Base Sequence; Guanine; Hot Temperature; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Nucleic Acid Heteroduplexes; RNA; RNA, Ribosomal; Thermodynamics; Uracil | 1999 |
4-chloro-o-phenylenediamine induces a dose-related increase in G:C > T:A transversions and one major DNA adduct in the liver of Big Blue mice after 26 weeks in feed treatment.
Topics: Adenine; Animal Feed; Animals; Cytosine; DNA Adducts; Dose-Response Relationship, Drug; Female; Guanine; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutagens; Phenylenediamines; Point Mutation; Thymine | 1999 |
Structure and recognition of sheared tandem G x A base pairs associated with human centromere DNA sequence at atomic resolution.
Topics: Adenine; Base Pair Mismatch; Base Pairing; Base Sequence; Centromere; Cobalt; DNA; Guanine; Humans; Ligands; Magnesium; Nucleic Acid Conformation; Nucleic Acid Heteroduplexes; Oligodeoxyribonucleotides; Spermine; Tandem Repeat Sequences; Water | 1999 |
Rapid exchange of A:T base pairs is essential for recognition of DNA homology by human Rad51 recombination protein.
Topics: Adenine; Base Pair Mismatch; Base Pairing; Base Sequence; Crossing Over, Genetic; Cytosine; DNA; DNA Repair; DNA-Binding Proteins; Fluorescence; Guanine; Humans; Inosine; Kinetics; Mutation; Oligodeoxyribonucleotides; Rad51 Recombinase; Sequence Homology, Nucleic Acid; Thymine | 1999 |
Localization of chloroacetaldehyde-induced DNA damage in human p53 gene by DNA polymerase fingerprint analysis.
Topics: Acetaldehyde; Adenine; Animals; Cytosine; DNA Damage; DNA Fingerprinting; DNA Repair; Exons; Genes, p53; Guanine; Hemangiosarcoma; Humans; Liver Neoplasms; Mutation; Rats; Sequence Analysis, DNA | 1999 |
Novel missense mutations in the glutamate dehydrogenase gene in the congenital hyperinsulinism-hyperammonemia syndrome.
Topics: Adenine; Ammonia; Codon; Cytosine; Female; Glutamate Dehydrogenase; Guanine; Heterozygote; Humans; Hyperinsulinism; Hypoglycemia; Infant; Infant, Newborn; Male; Mutation, Missense; Seizures; Syndrome; Thymine; Unconsciousness | 2000 |
Development of a whole cell assay to measure methotrexate-induced inhibition of thymidylate synthase and de novo purine synthesis in leukaemia cells.
Topics: Adenine; Antimetabolites, Antineoplastic; Child; Guanine; Humans; Inosine; Leukemia; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Purines; Thymidine; Thymidylate Synthase; Tumor Cells, Cultured | 2000 |
The RNA splicing factor hSlu7 is required for correct 3' splice-site choice.
Topics: Adenine; Binding Sites; Exons; Guanine; HeLa Cells; Humans; Ribonucleoproteins, Small Nuclear; RNA Precursors; RNA Splicing; RNA Splicing Factors; RNA-Binding Proteins; Spliceosomes | 1999 |
H-ras gene mutations in salivary gland mucoepidermoid carcinomas.
Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Carcinoma, Mucoepidermoid; Child; Codon; Disease Progression; Female; Gene Expression Regulation; Gene Frequency; Genes, ras; Guanine; Humans; Incidence; Male; Middle Aged; Point Mutation; Salivary Gland Neoplasms; Thymine; Valine | 2000 |
Using polymerase arrest to detect DNA binding specificity of aristolochic acid in the mouse H-ras gene.
Topics: Adenine; Animals; Aristolochic Acids; Base Composition; Carcinogens; Codon; Deoxyadenosines; Deoxyguanosine; DNA Adducts; DNA Damage; DNA Replication; DNA-Directed DNA Polymerase; DNA, Recombinant; Genes, ras; Guanine; Mice; Oligodeoxyribonucleotides; Phenanthrenes; Plasmids; Templates, Genetic | 2000 |
Adenine N3 is a main alkylation site of styrene oxide in double-stranded DNA.
Topics: Adenine; Alkylating Agents; Alkylation; Animals; Carcinogens; Chromatography, High Pressure Liquid; DNA; DNA Adducts; Epoxy Compounds; Guanine; Hydrogen-Ion Concentration; Hydrolysis; Male; Salmon; Testis | 2000 |
Identification of two rare variants (G-->A at nucleotide 721; C-->T at nucleotide 5200) in the rhodopsin gene. Mutations in brief no. 187. Online.
Topics: Adenine; Cytosine; Guanine; Humans; Point Mutation; Retinitis Pigmentosa; Rhodopsin; Thymine | 1998 |
Single-fiber analysis of mitochondrial A3243G mutation in four different phenotypes.
Topics: Adenine; Adult; Child; Diabetes Mellitus; DNA, Mitochondrial; Guanine; Humans; Leigh Disease; MELAS Syndrome; Middle Aged; Muscle Fibers, Skeletal; Muscle, Skeletal; Ophthalmoplegia, Chronic Progressive External; Point Mutation | 2000 |
Thermophilic bacteria strictly obey Szybalski's transcription direction rule and politely purine-load RNAs with both adenine and guanine.
Topics: Adenine; Base Composition; Cytosine Nucleotides; Genes, Bacterial; Guanine; Guanine Nucleotides; Hot Temperature; Methanococcus; Purines; Replication Origin; RNA, Bacterial; Transcription, Genetic | 2000 |
Observation of internucleotide NH...N hydrogen bonds in the absence of directly detectable protons.
Topics: Adenine; Base Pairing; Guanine; Hydrogen Bonding; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Protons | 1999 |
In vitro antihepadnaviral activities of combinations of penciclovir, lamivudine, and adefovir.
Topics: Acyclovir; Adenine; Animals; Antiviral Agents; Cells, Cultured; Drug Interactions; Drug Therapy, Combination; Ducks; Guanine; Hepadnaviridae Infections; Hepatitis B Virus, Duck; Humans; Lamivudine; Liver; Organophosphonates; Virus Replication | 2000 |
Substrate specificity of human methylpurine DNA N-glycosylase.
Topics: Adenine; Binding, Competitive; DNA; DNA Glycosylases; DNA Repair; Guanine; Guanosine; Humans; Hypoxanthine; Kinetics; N-Glycosyl Hydrolases; Oligonucleotides; Recombinant Proteins; Substrate Specificity | 2000 |
Identification of human MutY homolog (hMYH) as a repair enzyme for 2-hydroxyadenine in DNA and detection of multiple forms of hMYH located in nuclei and mitochondria.
Topics: Adenine; Amino Acid Sequence; Blotting, Western; Cell Extracts; Cell Nucleus; DNA; DNA Glycosylases; DNA Repair; Gene Expression Profiling; Guanine; HeLa Cells; Humans; Isoenzymes; Jurkat Cells; Mitochondria; Molecular Sequence Data; Molecular Weight; N-Glycosyl Hydrolases; Peptides; Recombinant Proteins; RNA, Messenger; Sequence Alignment; Substrate Specificity | 2000 |
In vitro DNA deamination by alpha-nitrosaminoaldehydes determined by GC/MS-SIM quantitation.
Topics: Adenine; Aldehydes; Animals; Cattle; Cytosine; Deamination; Diethylnitrosamine; DNA; Gas Chromatography-Mass Spectrometry; Guanine; Nitrosamines | 2000 |
Mutagenic specificity of imidazole ring-opened 7-methylpurines in M13mp18 phage DNA.
Topics: Adenine; Base Sequence; DNA Damage; DNA Methylation; DNA-Formamidopyrimidine Glycosylase; DNA, Viral; Escherichia coli; Escherichia coli Proteins; Guanine; Imidazoles; Lac Operon; Molecular Sequence Data; Mutagens; Mutation; N-Glycosyl Hydrolases; Pyrimidines; Transfection | 1999 |
Lamivudine, adefovir and tenofovir exhibit long-lasting anti-hepatitis B virus activity in cell culture.
Topics: Acyclovir; Adenine; Antiviral Agents; Carcinoma, Hepatocellular; DNA, Viral; Guanine; Hepatitis B virus; Lamivudine; Organophosphonates; Organophosphorus Compounds; Tenofovir; Tumor Cells, Cultured | 2000 |
A dimeric DNA interface stabilized by stacked A.(G.G.G.G).A hexads and coordinated monovalent cations.
Topics: Adenine; Base Pair Mismatch; Base Pairing; Base Sequence; Binding Sites; Cations, Monovalent; Computer Simulation; Dimerization; DNA; Guanine; Hydrogen Bonding; Ligands; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Osmolar Concentration; Protons; Sodium; Static Electricity; Telomerase; Thermodynamics; Water | 2000 |
Sensitivity of human type II topoisomerases to DNA damage: stimulation of enzyme-mediated DNA cleavage by abasic, oxidized and alkylated lesions.
Topics: Adenine; Alkylation; Apurinic Acid; Base Sequence; DNA; DNA Adducts; DNA Damage; DNA Repair; DNA Topoisomerases, Type II; DNA-Binding Proteins; Guanine; Humans; Isoenzymes; Mutation; Oligonucleotides; Oxidation-Reduction; Plasmids; Sensitivity and Specificity | 2000 |
Multiple analysis of three common genetic alterations associated with thrombophilia.
Topics: Adenine; Australia; Biotechnology; DNA; Factor V; Genetic Variation; Genotype; Guanine; Heterozygote; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Polymerase Chain Reaction; Spectrophotometry; Thrombophilia; Venous Thrombosis | 2000 |
Inhibition of the replication of the DNA polymerase M550V mutation variant of human hepatitis B virus by adefovir, tenofovir, L-FMAU, DAPD, penciclovir and lobucavir.
Topics: Acyclovir; Adenine; Antiviral Agents; Arabinofuranosylcytosine Triphosphate; Cell Line; Dioxolanes; DNA-Directed DNA Polymerase; DNA, Viral; Guanine; Hepatitis B virus; Humans; Organophosphonates; Organophosphorus Compounds; Purine Nucleosides; Tenofovir; Virus Replication | 2000 |
Further studies of KMnO4 oxidation of synthetic DNAs containing oxidatively damaged bases.
Topics: Adenine; Base Sequence; DNA; DNA Damage; Guanine; Oligodeoxyribonucleotides; Oxidation-Reduction; Potassium Permanganate; Uracil | 1999 |
Disturbance of genetic information by a ribonucleotide analogue.
Topics: Adenine; Base Pairing; Base Sequence; DNA, Complementary; Guanine; Mutagenesis, Site-Directed; Oxazines; Pyrimidines; Retroviridae; Reverse Transcriptase Polymerase Chain Reaction; RNA, Viral; Stereoisomerism; Transcription, Genetic | 1999 |
Is a closing "GA pair" a rule for stable loop-loop RNA complexes?
Topics: Adenine; Base Pairing; Escherichia coli; Guanine; HIV-1; Humans; Kinetics; Models, Molecular; Nucleic Acid Conformation; Nucleic Acid Denaturation; Oligoribonucleotides; Plasmids; RNA; RNA, Viral; Thermodynamics; Transcriptional Activation | 2000 |
Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis.
Topics: Adenine; Adenoma; Carcinoma; Colorectal Neoplasms; DNA Methylation; Gene Silencing; Genes, p53; Genes, ras; Guanine; Humans; O(6)-Methylguanine-DNA Methyltransferase; Point Mutation; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction | 2000 |
The interactions of square platinum(II) complexes with guanine and adenine: a quantum-chemical ab initio study of metalated tautomeric forms.
Topics: Adenine; Chemical Phenomena; Chemistry, Physical; Cisplatin; Electrochemistry; Guanine; Ligands; Molecular Conformation; Platinum; Protons | 2000 |
Identification of a GA-rich sequence as a protein-binding site in the 3'-untranslated region of chicken elastin mRNA with a potential role in the developmental regulation of elastin mRNA stability.
Topics: 3' Untranslated Regions; Adenine; Animals; Base Sequence; Binding Sites; Cattle; Chickens; Dinucleotide Repeats; Elastin; Gene Expression Regulation, Developmental; Guanine; Humans; Molecular Sequence Data; Organ Specificity; Rats; RNA, Messenger; Sequence Alignment; Sequence Deletion; Sequence Homology, Nucleic Acid; Sheep | 2000 |
Rates of platination of -AG- and -GA- containing double-stranded oligonucleotides: effect of chloride concentration.
Topics: Adenine; Base Sequence; Cisplatin; Guanine; Kinetics; Models, Chemical; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Oligodeoxyribonucleotides | 2000 |
Synthesis and characterization of oligonucleotides containing site-specific bulky N2-aralkylated guanines and N6-aralkylated adenines.
Topics: Adenine; Alkylation; Benzyl Compounds; Chromatography, High Pressure Liquid; DNA Adducts; Guanine; Mutagenesis, Site-Directed; Mutagens; Nucleosides; Oligonucleotides; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Ultraviolet | 2000 |
Detecting hypermutations in viral sequences with an emphasis on G --> A hypermutation.
Topics: Adenine; Animals; Guanine; Humans; Point Mutation; Software; Viruses | 2000 |
Infrared spectroscopy of the photo- and radiobiology of DNA bases and their derivatives.
Topics: Adenine; Cytosine; Guanine; Radiation, Ionizing; Spectrophotometry, Infrared; Thymine; Ultraviolet Rays; Uracil | 1974 |
Induction of apoptosis and inhibition of signalling pathways by alkylated purines.
Topics: Adenine; Alkylation; Androstadienes; Animals; Antibiotics, Antineoplastic; Apoptosis; Cell Line; Cricetinae; DNA Fragmentation; Electrophoresis, Agar Gel; Enzyme Inhibitors; Fibroblasts; G1 Phase; Genes, p53; Guanine; MAP Kinase Signaling System; Mutation; Phosphorylation; Purines; Resting Phase, Cell Cycle; Ribosomal Protein S6 Kinases; Signal Transduction; Sirolimus; Wortmannin | 2000 |
Portal vein thrombosis associated to prothrombin G20210A mutation and protein C deficiency.
Topics: Adenine; Adult; Guanine; Humans; Magnetic Resonance Imaging; Male; Point Mutation; Portal Vein; Protein C Deficiency; Prothrombin; Venous Thrombosis | 2000 |
Selective blockage of the 3'-->5' exonuclease activity of WRN protein by certain oxidative modifications and bulky lesions in DNA.
Topics: Adenine; Base Sequence; DNA; DNA Adducts; DNA Helicases; DNA Polymerase I; Exodeoxyribonucleases; Exonucleases; Guanine; Hypoxanthine; Mutation; Oxidation-Reduction; RecQ Helicases; Substrate Specificity; Uracil; Werner Syndrome Helicase | 2000 |
A new polymorphism, g119A>G, in the integrin alpha 7 (ITGA7) gene.
Topics: Adenine; Antigens, CD; Genetic Markers; Guanine; Humans; Integrin alpha Chains; Integrins; Muscular Diseases; Mutation, Missense; Polymorphism, Genetic; Retrospective Studies | 2000 |
Factors affecting the thermodynamic stability of small asymmetric internal loops in RNA.
Topics: Adenine; Base Pair Mismatch; Base Pairing; Guanine; Hot Temperature; Hydrogen Bonding; Imines; Models, Chemical; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Nucleic Acid Heteroduplexes; Oligodeoxyribonucleotides; Protons; RNA; Thermodynamics; Uracil | 2000 |
A retroviral RNA kissing complex containing only two G.C base pairs.
Topics: Adenine; Base Pairing; Base Sequence; Cytosine; Dimerization; Guanine; Models, Molecular; Moloney murine leukemia virus; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Denaturation; RNA Stability; RNA, Viral; Static Electricity; Temperature; Ultraviolet Rays | 2000 |
Reduction of GC --> TA transversion mutation by overexpression of MutS in Escherichia coli K-12.
Topics: Adenine; Adenosine Triphosphatases; Bacterial Proteins; Base Pair Mismatch; Cystine; DNA Repair; DNA-Binding Proteins; Escherichia coli; Escherichia coli Proteins; Gene Expression; Genes, Bacterial; Guanine; Mutation; MutS DNA Mismatch-Binding Protein; Thymine | 2000 |
DXYS267: DYS393 and its X chromosome counterpart.
Topics: Adenine; Alleles; Base Pairing; Chimera; Chromosome Mapping; Cytosine; DNA; DNA Primers; Evolution, Molecular; Female; Forensic Medicine; Gene Amplification; Gene Frequency; Genetic Variation; Guanine; Heterozygote; Humans; Male; Norway; Polymorphism, Genetic; Sequence Analysis, DNA; Tandem Repeat Sequences; Thymine; X Chromosome; Y Chromosome | 2000 |
In vivo repair of methylation damage in Aag 3-methyladenine DNA glycosylase null mouse cells.
Topics: Adenine; Animals; Cell Line; DNA Adducts; DNA Damage; DNA Glycosylases; DNA Methylation; DNA Repair; DNA Replication; Gene Deletion; Genotype; Guanine; Guanosine; Methylnitrosourea; Mice; Mice, Knockout; N-Glycosyl Hydrolases | 2000 |
Use of an N-terminal fragment from moloney murine leukemia virus reverse transcriptase to facilitate crystallization and analysis of a pseudo-16-mer DNA molecule containing G-A mispairs.
Topics: Adenine; Base Pair Mismatch; Carbohydrate Conformation; Crystallization; Crystallography, X-Ray; Deoxyribose; DNA; Guanine; Models, Molecular; Moloney murine leukemia virus; Nucleic Acid Conformation; Peptide Fragments; Protein Conformation; RNA-Directed DNA Polymerase | 2000 |
Repair of A/G and A/8-oxoG mismatches by MutY adenine DNA glycosylase.
Topics: Adenine; Base Pair Mismatch; Binding Sites; DNA Glycosylases; DNA Primers; DNA Repair; Escherichia coli; Guanine; Kinetics; Mutation; N-Glycosyl Hydrolases; Polymerase Chain Reaction | 2000 |
Purine-induced alterations of dopamine metabolism in rat pheochromocytoma PC12 cells.
Topics: Adenine; Adenosine; Animals; Disease Models, Animal; Dopamine; Guanine; Guanosine; Hypoxanthine; Neostriatum; Neural Pathways; Neurons; Parkinson Disease; PC12 Cells; Purines; Rats; Substantia Nigra; Uric Acid; Xanthine | 2000 |
A novel deletion in exon 12 (g1845delAG or g1846delGA) of the CFTR (ABCC7) gene in a CF infant presenting with meconium ileus.
Topics: Adenine; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Exons; Guanine; Humans; Infant, Newborn; Intestinal Obstruction; Male; Meconium; Sequence Deletion | 2000 |
Products from polycrystalline DNA constituents after X-irradiation and heavy-ion bombardment: formation of the 5,6-dihydroadduct in thymidine 5'-monophosphate and release of unaltered bases in nucleotides.
Topics: Adenine; Chromatography, High Pressure Liquid; Cytosine; DNA; DNA Adducts; Dose-Response Relationship, Radiation; Guanine; Heavy Ions; Magnetic Resonance Spectroscopy; Models, Chemical; Oligonucleotides; Thymidine Monophosphate; X-Rays | 2000 |
HMG-domain protein recognition of cisplatin 1,2-intrastrand d(GpG) cross-links in purine-rich sequence contexts.
Topics: Adenine; Base Sequence; Cisplatin; Deoxyguanosine; Dinucleoside Phosphates; DNA Adducts; DNA Probes; Guanine; High Mobility Group Proteins; Mutagenesis, Site-Directed; Nucleic Acid Heteroduplexes; Oligonucleotides; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins | 2000 |
Synthesis and structure determination of 6-methylbenzo[a]pyrene-deoxyribonucleoside adducts and their identification and quantitation in vitro and in mouse skin.
Topics: Adenine; Animals; Benzopyrenes; Biotransformation; Carcinogens; Cattle; Deoxyribonucleotides; DNA Adducts; Female; Guanine; Iodine; Mice; Oxidation-Reduction; Skin; Spectrometry, Mass, Fast Atom Bombardment | 2000 |
Method for the synthesis of uric acid derivatives.
Topics: 1-Propanol; Adenine; Alkylation; Ammonia; Guanine; Hydrocarbons, Iodinated; Mass Spectrometry; Methylation; Purines; Uric Acid | 2000 |
Novel single nucleotide polymorphisms (3203A>G and 3204C>T) in the 3' end of the mitochondrial 16S rRNA gene.
Topics: 3' Untranslated Regions; Adenine; Base Sequence; Cytosine; Diabetes Mellitus, Type 2; Guanine; Humans; Mitochondria; Molecular Sequence Data; Polymorphism, Single Nucleotide; RNA, Ribosomal, 16S; Thymine | 2000 |
"Paper-clip" type triple helix formation by 5'-d-(TC)3Ta(CT)3Cb(AG)3 (a and b = 0-4) as a function of loop size with and without the pseudoisocytosine base in the Hoogsteen strand.
Topics: Adenine; Base Composition; Base Pairing; Base Sequence; Cytidine; Cytosine; DNA; Guanine; Magnesium Chloride; Nucleic Acid Conformation; Nucleic Acid Denaturation; Oligodeoxyribonucleotides; Protons; Thermodynamics; Thionucleotides; Thymine | 2000 |
Association between mutations of the follicle-stimulating-hormone receptor and repeated twinning.
Topics: Adenine; Adult; Alanine; Asparagine; Codon; Exons; Female; Genetic Linkage; Guanine; Humans; Phenotype; Point Mutation; Receptors, FSH; Serine; Threonine; Twins, Dizygotic | 2000 |
Single 8-oxo-guanine and 8-oxo-adenine lesions induce marked changes in the backbone structure of a 25-base DNA strand.
Topics: Adenine; DNA; DNA Damage; Guanine; Hydroxyl Radical; Multivariate Analysis; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Spectroscopy, Fourier Transform Infrared | 2000 |
Genetic variants in the promoter (g983G>T) and coding region (A92T) of the human cardiotrophin-1 gene (CTF1) in patients with dilated cardiomyopathy.
Topics: Adenine; Animals; Cardiomyopathy, Dilated; Codon; Cytokines; Genetic Variation; Guanine; Humans; Mutation, Missense; Polymorphism, Genetic; Promoter Regions, Genetic; Rodentia; Thymine | 2000 |
A novel SSCP variant (c.828G>A) within the M2 domain of the human neuronal nicotinic acetylcholine receptor alpha 4 subunit gene, CHRNA4.
Topics: Adenine; Epilepsies, Partial; Epilepsy, Frontal Lobe; Genetic Variation; Guanine; Humans; Neurons; Polymorphism, Single-Stranded Conformational; Protein Structure, Tertiary; Receptors, Nicotinic | 2000 |
Identification of 6 new polymorphisms, g.11177G>A, g.14622C>T (R49C), g.17540T>C, g.17639T>C, g.30929T>C, g.31074G>A (R454Q), in the human microsomal epoxide hydrolase gene (EPHX1) in a French population.
Topics: Adenine; Amino Acid Substitution; Arginine; Cysteine; Cytosine; Epoxide Hydrolases; France; Glutamine; Guanine; Humans; Microsomes; Mutation, Missense; Polymorphism, Genetic; Thymine | 2000 |
A novel polymorphism (g722G>A) in exon 2 of the AVPR2 gene.
Topics: Adenine; Alanine; Diabetes Insipidus, Nephrogenic; Exons; Guanine; Humans; Polymorphism, Genetic; Receptors, Vasopressin; X Chromosome | 2000 |
Inherited thrombophilic risk factors and venous thromboembolism: distinct role in peripheral deep venous thrombosis and pulmonary embolism.
Topics: Activated Protein C Resistance; Adenine; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antibodies, Antiphospholipid; Anticoagulants; Case-Control Studies; Child; Confidence Intervals; Factor V; Female; Gene Frequency; Guanine; Humans; Male; Middle Aged; Odds Ratio; Point Mutation; Prothrombin; Pulmonary Embolism; Retrospective Studies; Risk Factors; Sex Factors; Thromboembolism; Thrombophilia; Venous Thrombosis | 2000 |
CTLA-4 gene polymorphism at position 49 in exon 1 reduces the inhibitory function of CTLA-4 and contributes to the pathogenesis of Graves' disease.
Topics: Abatacept; Adenine; Adjuvants, Immunologic; Alleles; Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation; Cell Division; Cell Line; CTLA-4 Antigen; Dose-Response Relationship, Immunologic; Down-Regulation; Exons; Graves Disease; Guanine; Immunoconjugates; Immunosuppressive Agents; Intracellular Fluid; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Membrane Proteins; Polymorphism, Genetic; Solubility | 2000 |
Novel silent variant (c1722G>A) in the coding region of the insulin receptor substrate 1 (IRS1) gene.
Topics: Adenine; Genetic Variation; Glycine; Guanine; Humans; Insulin Receptor Substrate Proteins; Phosphoproteins; Polymorphism, Genetic; Receptor, Insulin; Signal Transduction | 2000 |
Sequence bias in edited kinetoplastid RNAs.
Topics: Adenine; Animals; Base Composition; Base Pairing; Base Sequence; DNA Transposable Elements; DNA, Kinetoplast; DNA, Mitochondrial; Guanine; RNA Editing; RNA Precursors; RNA, Protozoan; Sequence Deletion; Transcription, Genetic; Trypanosoma brucei brucei | 2000 |
Femtosecond direct observation of charge transfer between bases in DNA.
Topics: 2-Aminopurine; Adenine; Base Pairing; DNA; Electron Transport; Guanine; Inosine; Models, Molecular; Time Factors | 2000 |
Re: population-based, case-control study of HER2 genetic polymorphism and breast cancer risk.
Topics: Adenine; Africa; Alleles; Black or African American; Black People; Breast Neoplasms; Case-Control Studies; China; Female; Gene Expression Regulation, Neoplastic; Genotype; Guanine; Humans; Polymorphism, Genetic; Receptor, ErbB-2; Risk; Risk Factors; United States; Valine; White People | 2000 |
Interaction of guanine phosphonomethoxyalkyl derivatives with GMP kinase isoenzymes.
Topics: Adenine; Animals; Antineoplastic Agents; Guanine; Guanosine Monophosphate; Guanylate Kinases; Isoenzymes; Kinetics; Nucleoside-Phosphate Kinase; Organophosphorus Compounds; Phosphorylation; Substrate Specificity; Swine | 2000 |
An unexpectedly high excision capacity for mispaired 5-hydroxymethyluracil in human cell extracts.
Topics: Adenine; Base Pairing; Cell Extracts; Cell Line; DNA Damage; DNA Glycosylases; DNA Repair; Fibroblasts; Guanine; HeLa Cells; Humans; N-Glycosyl Hydrolases; Pentoxyl | 2000 |
Androgen-receptor gene CAG repeats, plasma testosterone levels, and risk of hepatitis B-related hepatocellular carcinoma.
Topics: Adenine; Adult; Aged; Carcinoma, Hepatocellular; Case-Control Studies; Cohort Studies; Cytosine; Guanine; Hepatitis B, Chronic; Humans; Liver Neoplasms; Male; Middle Aged; Odds Ratio; Prospective Studies; Receptors, Androgen; Risk; Testosterone; Trinucleotide Repeats | 2000 |
Adenine excisional repair function of MYH protein on the adenine:8-hydroxyguanine base pair in double-stranded DNA.
Topics: Adenine; Animals; Base Pair Mismatch; Base Sequence; Carbon-Oxygen Lyases; Deoxyribonuclease IV (Phage T4-Induced); DNA; DNA Glycosylases; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; DNA-Formamidopyrimidine Glycosylase; Escherichia coli; Escherichia coli Proteins; Genes, Bacterial; Genetic Complementation Test; Guanine; Humans; Kinetics; Mitochondria; Mutation; N-Glycosyl Hydrolases; Nuclear Proteins; Oligodeoxyribonucleotides; Polymorphism, Single Nucleotide; Potassium Chloride; Protein Binding; Protein Isoforms; Recombinant Fusion Proteins; Schizosaccharomyces; Sodium Chloride; Spodoptera | 2000 |
Oxidative damage in pregnant diabetic rats and their embryos.
Topics: Adenine; Animals; Congenital Abnormalities; Cytosine; Diabetes Mellitus, Experimental; DNA Adducts; DNA Damage; Female; Fetus; Gas Chromatography-Mass Spectrometry; Guanine; Hydantoins; Hydroxylation; Liver; Oxidative Stress; Pregnancy; Pregnancy in Diabetics; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Uracil; Vitamin E | 2000 |
A new Msp I polymorphism (g1741G>A) in intron 3 of the human delta-aminolevulinate dehydratase gene.
Topics: Adenine; Deoxyribonuclease HpaII; Guanine; Humans; Introns; Point Mutation; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Porphobilinogen Synthase; Restriction Mapping | 2001 |
Association of the TNF-alpha-308 (G-->A) polymorphism with self-reported history of childhood asthma.
Topics: Adenine; Asia; Asthma; Child; Ethnicity; Female; Genotype; Guanine; Humans; Peptidyl-Dipeptidase A; Point Mutation; Polymorphism, Genetic; Pregnancy; Tumor Necrosis Factor-alpha; United Kingdom | 2000 |
Differential adsorption of nucleic acid bases: Relevance to the origin of life.
Topics: Adenine; Adsorption; Cytosine; Guanine; Hypoxanthine; Origin of Life; Purines; Pyrimidines; RNA; Surface Properties; Thymine; Uracil | 2001 |
Detection of competing DNA structures by thermal gradient gel electrophoresis: from self-association to triple helix formation by (G,A)-containing oligonucleotides.
Topics: Adenine; Base Sequence; Binding, Competitive; DNA; Electrophoresis, Polyacrylamide Gel; Guanine; Magnesium; Nucleic Acid Denaturation; Oligonucleotides; Spectrophotometry, Ultraviolet; Temperature; Thermodynamics | 2001 |
Anti-gene effect in live cells of AG motif triplex-forming oligonucleotides containing an increasing number of phosphorothioate linkages.
Topics: Adenine; Animals; Base Sequence; Cell Line; Chloramphenicol O-Acetyltransferase; Dinucleotide Repeats; DNA; DNA Footprinting; Electrophoresis, Polyacrylamide Gel; Genes, ras; Genes, Reporter; Guanine; Humans; Mice; Molecular Sequence Data; Nucleic Acid Conformation; Oligonucleotides; Promoter Regions, Genetic; Single-Strand Specific DNA and RNA Endonucleases; Stereoisomerism; Suppression, Genetic; Thionucleotides; Transfection | 2001 |
Thermodynamics of ion-induced RNA folding in the hammerhead ribozyme: an isothermal titration calorimetric study.
Topics: Adenine; Animals; Binding Sites; Calorimetry; Cations, Divalent; Deoxyguanosine; Genetic Variation; Guanine; Magnesium; Models, Chemical; Nucleic Acid Conformation; RNA, Catalytic; RNA, Protozoan; Thermodynamics; Titrimetry | 2001 |
Achondroplasia with the FGFR3 1138g-->a (G380R) mutation in two sibs sharing a 4p haplotype derived from their unaffected father.
Topics: Achondroplasia; Adenine; Adult; Amino Acid Substitution; Arginine; Child; Female; Glycine; Guanine; Haplotypes; Humans; Male; Nuclear Family; Pedigree; Point Mutation; Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 3; Receptors, Fibroblast Growth Factor | 2000 |
The -403 G-->A promoter polymorphism in the RANTES gene is associated with atopy and asthma.
Topics: Adenine; Adult; Airway Obstruction; Asthma; Chemokine CCL5; Female; Genotype; Guanine; Humans; Hypersensitivity, Immediate; Male; Polymorphism, Single Nucleotide; Promoter Regions, Genetic | 2000 |
Quantum chemistry predicted correlations between geometric isomerism (conformation) of -OH and =NH substituents and typical group frequencies of nucleic acid bases: cytosine.
Topics: Adenine; Calorimetry; Cytosine; Guanine; Isomerism; Models, Molecular; Molecular Conformation; Quantum Theory; Uracil; Xanthine | 2001 |
Polymorphism of the D12S66 system in the Japanese population and its detection using degraded DNA.
Topics: Adenine; Alleles; Base Pairing; Blood; Chromosome Mapping; Coloring Agents; DNA; Electrophoresis, Polyacrylamide Gel; Genetic Carrier Screening; Genotype; Guanine; Humans; Japan; Polymerase Chain Reaction; Polymorphism, Genetic; Reproducibility of Results; Silver Nitrate; Tandem Repeat Sequences; Thymine; Tooth | 2000 |
Reaction of N-n-butyl-N-nitrosourea with DNA in vitro.
Topics: Adenine; Alkylation; Animals; Carbon Radioisotopes; Carcinogens; Cattle; Chromatography, Ion Exchange; DNA; DNA Damage; Guanine; Isotope Labeling; Nitrosourea Compounds; Spectrophotometry, Ultraviolet | 1980 |
Repair of ethylnitrosourea-induced DNA damage in the newborn rat. I. Alkali-labile lesions and in situ breaks.
Topics: Adenine; Alkylating Agents; Animals; Animals, Newborn; Brain; DNA; DNA Damage; DNA Repair; Ethylnitrosourea; Female; Guanine; Hydrogen-Ion Concentration; Kidney; Liver; Lung; Male; Rats; Rats, Sprague-Dawley; Sodium Hydroxide | 1980 |
Evidence for the involvement of lesions other than O6-alkylguanine in mammalian cell mutagenesis.
Topics: Adenine; Alkylating Agents; Animals; Carcinogens; Cricetinae; DNA; DNA Damage; Drug Resistance; Guanine; Hypoxanthine Phosphoribosyltransferase; Methyl Methanesulfonate; Methylnitrosourea; Mutagenesis; Mutagens; Sulfuric Acid Esters; Thioguanine | 1980 |
Application of magdala red as a fluorescence probe in the determination of nucleic acids.
Topics: Adenine; Animals; Cattle; Cytosine; DNA; Fluorescent Dyes; Guanine; Indicators and Reagents; Naphthalenes; Proteins; Pyrazines; Reproducibility of Results; RNA; RNA, Fungal; Saccharomyces cerevisiae; Salmon; Sensitivity and Specificity; Spectrometry, Fluorescence; Thymine; Thymus Gland | 2000 |
Structure, folding and activity of the VS ribozyme: importance of the 2-3-6 helical junction.
Topics: Adenine; Base Sequence; Catalysis; Computer Simulation; Energy Transfer; Fluorescence; Guanine; Mitochondria; Models, Molecular; Molecular Sequence Data; Neurospora; Nucleic Acid Conformation; RNA, Catalytic | 2001 |
Low-energy (5-40 eV) electron-stimulated desorption of anions from physisorbed DNA bases.
Topics: Adenine; Adsorption; Anions; Cytosine; DNA; DNA Damage; Electrons; Free Radicals; Guanine; Heterocyclic Compounds; Mass Spectrometry; Powders; Thymine; Uracil | 2001 |
Functionally different AU- and G-rich cis-elements confer developmentally regulated mRNA stability in Trypanosoma cruzi by interaction with specific RNA-binding proteins.
Topics: Adenine; Animals; Base Composition; Base Sequence; Binding Sites; Chloramphenicol O-Acetyltransferase; Gene Expression Regulation, Developmental; Guanine; Molecular Sequence Data; RNA-Binding Proteins; RNA, Messenger; RNA, Protozoan; Transfection; Trypanosoma cruzi; Uracil | 2001 |
Dimethylsulfoxide-stabilized conformer of guanine-adenine repeat strand of DNA.
Topics: Adenine; Circular Dichroism; Dimethyl Sulfoxide; DNA, Single-Stranded; Drug Stability; Guanine; Nucleic Acid Conformation; Repetitive Sequences, Nucleic Acid | 2001 |
Beta-fibrinogen gene -455G/A polymorphism and coronary heart disease incidence: the Atherosclerosis Risk in Communities (ARIC) Study.
Topics: Adenine; Alleles; Arteriosclerosis; Cohort Studies; Coronary Disease; Fibrinogen; Genotype; Guanine; Humans; Incidence; Male; Middle Aged; Polymorphism, Genetic; Prospective Studies; Risk Factors; United States | 2001 |
15-mer DNA duplexes containing an abasic site are thermodynamically more stable with adjacent purines than with pyrimidines.
Topics: Adenine; Apurinic Acid; Base Composition; Base Pairing; Base Sequence; Cytosine; DNA; Guanine; Models, Molecular; Nucleic Acid Conformation; Nucleic Acid Heteroduplexes; Oligodeoxyribonucleotides; Polynucleotides; Purine Nucleotides; Pyrimidine Nucleotides; Spectrophotometry; Thermodynamics; Thymine | 2001 |
Synthesis and characterization of nucleosides and oligonucleotides bearing adducts of butadiene epoxides on adenine n(6) and guanine n(2).
Topics: Adenine; Base Sequence; Circular Dichroism; Epoxy Compounds; Guanine; Mass Spectrometry; Nuclear Magnetic Resonance, Biomolecular; Nucleosides; Oligonucleotides | 2001 |
Analysis of peroxynitrite reactions with guanine, xanthine, and adenine nucleosides by high-pressure liquid chromatography with electrochemical detection: C8-nitration and -oxidation.
Topics: Adenine; Chromatography, High Pressure Liquid; Electrochemistry; Guanine; Nitrates; Oxidation-Reduction; Purine Nucleosides; Xanthine | 2001 |
Association study of CAG repeats in the KCNN3 gene in Japanese patients with schizophrenia, schizoaffective disorder and bipolar disorder.
Topics: Adenine; Adult; Alleles; Asian People; Bipolar Disorder; Case-Control Studies; Cytosine; Female; Guanine; Humans; Japan; Male; Middle Aged; Polymorphism, Genetic; Potassium Channels; Potassium Channels, Calcium-Activated; Psychotic Disorders; Schizophrenia; Small-Conductance Calcium-Activated Potassium Channels; Thymine; Trinucleotide Repeats | 2001 |
Molecular modeling and biochemical characterization reveal the mechanism of hepatitis B virus polymerase resistance to lamivudine (3TC) and emtricitabine (FTC).
Topics: Acyclovir; Adenine; Amino Acid Sequence; Antiviral Agents; Cytidine Triphosphate; Deoxycytidine; Dideoxynucleotides; Drug Resistance, Microbial; Emtricitabine; Guanine; Hepatitis B virus; Humans; Lamivudine; Models, Molecular; Molecular Sequence Data; Organophosphonates; Protein Conformation; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Sequence Homology, Amino Acid | 2001 |
Actinomycin D binds strongly to d(TGTCATTG), a single-stranded DNA devoid of GpC sites.
Topics: Adenine; Base Sequence; Binding Sites; Circular Dichroism; Cytosine; Dactinomycin; Dinucleoside Phosphates; DNA, Single-Stranded; Guanine; Ligands; Nucleic Acid Conformation; Nucleic Acid Denaturation; Nucleic Acid Heteroduplexes; Oligodeoxyribonucleotides; Spectrometry, Fluorescence; Thymine | 2001 |
Macrochelation, cyclometallation and G-quartet formation: N3- and C8-bound PdII complexes of adenine and guanine.
Topics: Adenine; Base Pairing; Binding Sites; DNA; Guanine; Hydrogen Bonding; Ligands; Models, Molecular; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Palladium | 2001 |
A functional interaction of Ku with Werner exonuclease facilitates digestion of damaged DNA.
Topics: Adenine; Antigens, Nuclear; Cell Line; Cell Nucleus; DNA; DNA Damage; DNA Helicases; DNA-Binding Proteins; Exodeoxyribonucleases; Exonucleases; Guanine; HeLa Cells; Humans; Ku Autoantigen; Nuclear Proteins; RecQ Helicases; Replication Protein A; Werner Syndrome Helicase | 2001 |
Importance of specific nucleotides in the folding of the natural form of the hairpin ribozyme.
Topics: 2-Aminopurine; Adenine; Base Composition; Base Sequence; Carbocyanines; Cytosine; Deoxyribonucleosides; Energy Transfer; Fluorescein; Fluorescent Dyes; Guanine; Hydrolysis; Molecular Sequence Data; Nepovirus; Nucleic Acid Conformation; Oligonucleotides; Point Mutation; Purine Nucleotides; Ribose; RNA, Catalytic; Spectrometry, Fluorescence; Uridine | 2001 |
Aminoethylprolyl (aep) PNA: mixed purine/pyrimidine oligomers and binding orientation preferences for PNA:DNA duplex formation.
Topics: Adenine; Base Sequence; Circular Dichroism; Cytosine; DNA; Guanine; Molecular Structure; Nucleic Acid Conformation; Oligonucleotides, Antisense; Peptide Nucleic Acids; Proline; Sequence Analysis, DNA; Stereoisomerism; Thermodynamics; Thymine | 2001 |
A novel mutation in the keratin 13 gene causing oral white sponge nevus.
Topics: Adenine; Adolescent; Asparagine; Chromosome Mapping; Chromosomes, Human, Pair 12; Chromosomes, Human, Pair 17; Codon; Epithelium; Exons; Genetic Linkage; Guanine; Hamartoma; Humans; Keratins; Leukoplakia, Oral; Male; Mouth Diseases; Mutation, Missense; Protein Structure, Tertiary; Scotland; Serine | 2001 |
[Autosomal dominant cerebellar ataxias in the Netherlands: a national inventory].
Topics: Adenine; Adult; Age of Onset; Anticipation, Genetic; Cerebellar Ataxia; Child; Cytosine; DNA Mutational Analysis; Family; Female; Genetic Testing; Genotype; Guanine; Humans; Incidence; Male; Mutation; Netherlands; Prevalence; Trinucleotide Repeat Expansion | 2001 |
Nucleotide substitution in the ectodomain of trail receptor DR4 is associated with lung cancer and head and neck cancer.
Topics: Adenine; Adenocarcinoma; Adult; Age Factors; Aged; Aged, 80 and over; Alleles; Amino Acid Sequence; Apoptosis Regulatory Proteins; Black People; Carcinoma, Non-Small-Cell Lung; Case-Control Studies; Chromosomes, Human, Pair 8; Exons; Female; Guanine; Head and Neck Neoplasms; Heterozygote; Homozygote; Humans; Introns; Ligands; Lung Neoplasms; Male; Membrane Glycoproteins; Middle Aged; Models, Genetic; Molecular Sequence Data; Mutation, Missense; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Protein Structure, Tertiary; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Sequence Homology, Amino Acid; Stomach Neoplasms; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; White People | 2001 |
Differential DNA recognition and glycosylase activity of the native human MutY homolog (hMYH) and recombinant hMYH expressed in bacteria.
Topics: Adenine; Base Pair Mismatch; Blotting, Western; Cell Extracts; DNA; DNA Glycosylases; DNA Repair; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Guanine; Guanosine; Humans; N-Glycosyl Hydrolases; Phosphorylation; Precipitin Tests; Protein Binding; Recombinant Proteins; Sequence Homology, Amino Acid; Substrate Specificity; Thermodynamics; Tumor Cells, Cultured | 2001 |
Nonreplication of association between mu-opioid-receptor gene (OPRM1) A118G polymorphism and substance dependence.
Topics: Adenine; Adult; Alcoholism; Case-Control Studies; Female; Gene Frequency; Genetic Predisposition to Disease; Genetic Testing; Genotype; Guanine; Humans; Male; Middle Aged; Pedigree; Phenotype; Polymorphism, Genetic; Receptors, Opioid, mu; Substance-Related Disorders | 2001 |
A BRCA1 variant, IVS23+1G-->A, causes abnormal RNA splicing by deleting exon 23.
Topics: Adenine; Base Sequence; Exons; Female; Genes, BRCA1; Genetic Variation; Guanine; Humans; Lymphocytes; Molecular Sequence Data; Ovarian Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA Splicing; Sequence Deletion | 2001 |
hMYH cell cycle-dependent expression, subcellular localization and association with replication foci: evidence suggesting replication-coupled repair of adenine:8-oxoguanine mispairs.
Topics: Adenine; Base Pair Mismatch; Blotting, Western; Cell Cycle; Cell Division; Cell Line; Cell Nucleus; Cytoplasm; DNA Glycosylases; DNA Repair; DNA Repair Enzymes; DNA Replication; DNA-Formamidopyrimidine Glycosylase; Fluorescent Antibody Technique, Indirect; G1 Phase; Guanine; Humans; Mitochondria; N-Glycosyl Hydrolases; Phosphoric Monoester Hydrolases; Proliferating Cell Nuclear Antigen; Protein Transport; S Phase; Tumor Cells, Cultured | 2001 |
Psychiatric symptoms and CAG repeats in neurologically asymptomatic Huntington's disease gene carriers.
Topics: Adenine; Adult; Age of Onset; Cognition; Cytosine; Female; Genetic Predisposition to Disease; Guanine; Heterozygote; Humans; Huntington Disease; Irritable Mood; Male; Middle Aged; Prospective Studies; Psychiatric Status Rating Scales; Trinucleotide Repeat Expansion | 2001 |
Genetic polymorphism of the tumor necrosis factor (TNF)-alpha promoter region in families with localized early-onset periodontitis.
Topics: Adenine; Adolescent; Aggressive Periodontitis; Alleles; Bone Resorption; Child; DNA; Female; Genotype; Guanine; Humans; Inflammation Mediators; Male; Monocytes; Pedigree; Polymorphism, Genetic; Promoter Regions, Genetic; Tumor Necrosis Factor-alpha | 2001 |
Design and synthesis of a novel DNA-DNA interstrand adenine-guanine cross-linking agent.
Topics: Adenine; Alkylation; Antineoplastic Agents, Alkylating; Cross-Linking Reagents; DNA; Drug Screening Assays, Antitumor; Electrophoresis, Polyacrylamide Gel; Guanine; Humans; Indoles; Tumor Cells, Cultured | 2001 |
Direct observation of hole transfer through DNA by hopping between adenine bases and by tunnelling.
Topics: Adenine; DNA; Electrochemistry; Guanine; Nucleic Acid Conformation | 2001 |
Structure-based analysis of protein-RNA interactions using the program ENTANGLE.
Topics: Adenine; Amino Acid Motifs; Amino Acyl-tRNA Synthetases; Animals; Binding Sites; Computational Biology; Cytosine; Databases as Topic; Guanine; Humans; Hydrogen Bonding; Models, Molecular; Nucleic Acid Conformation; Protein Conformation; Ribosomal Proteins; RNA; RNA-Binding Proteins; Software; Static Electricity; Structure-Activity Relationship; Substrate Specificity; Uracil | 2001 |
Lack of association of -308A/G TNFA promoter and 196R/M TNFR2 polymorphisms with disease severity in Thai adult malaria patients.
Topics: Adenine; Adult; Amino Acid Substitution; Antigens, CD; Guanine; Humans; Malaria, Cerebral; Polymorphism, Genetic; Promoter Regions, Genetic; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type II; Severity of Illness Index; Tumor Necrosis Factor-alpha | 2001 |
Age-related radical-induced DNA damage is linked to prostate cancer.
Topics: Adenine; Age Factors; Cell Transformation, Neoplastic; DNA; DNA Damage; DNA, Neoplasm; Gas Chromatography-Mass Spectrometry; Guanine; Humans; Hydroxyl Radical; Logistic Models; Male; Middle Aged; Models, Biological; Prostate; Prostatic Neoplasms; Pyrimidines | 2001 |
HF-STEX and RASSCF calculations on nitrogen K-shell X-ray absorption of purine base and its derivative.
Topics: Adenine; Guanine; Models, Chemical; Nitrogen; Nucleic Acids | 2001 |
Some aspects of the role of vitamin B12 in nucleic acid synthesis in a neoplastic C3H mouse cell strain. I. Growth studies.
Topics: Adenine; Adenosine; Animals; Cell Division; Cytidine; Deoxyadenosines; Deoxycytidine; Deoxyuridine; DNA, Neoplasm; Folic Acid; Guanine; Mice; Nucleic Acid Precursors; Nucleosides; Pyrimidines; Thymidine; Tumor Cells, Cultured; Uridine; Vitamin B 12 | 1970 |
The prebiotic role of adenine: a critical analysis.
Topics: Adenine; Alkylation; Ammonia; Carbon Monoxide; Evolution, Chemical; Evolution, Molecular; Guanine; Hydrogen Bonding; Hydrogen Cyanide; Hydrogen-Ion Concentration; Hydrolysis; RNA; Uracil | 1995 |
Nucleic acid analogues and the origins of replication.
Topics: Adenine; DNA; Guanine; Hydrogen Cyanide; Models, Chemical; Pentoxyl | 1989 |
DNA dynamics in aqueous solution: opening the double helix.
Topics: Adenine; Algorithms; Base Composition; Computer Simulation; Cytosine; DNA; Guanine; Hydrogen; Models, Molecular; Oxygen; Software; Thymine; Water | 1990 |
Nonenzymatic template-directed synthesis on hairpin oligonucleotides. 3. Incorporation of adenosine and uridine residues.
Topics: Adenine; Adenosine; Base Composition; Base Sequence; Cytidine Monophosphate; Cytosine; Guanine; Guanosine Monophosphate; Molecular Sequence Data; Oligonucleotides; Polymers; Templates, Genetic; Thymidine; Thymine; Uridine | 1992 |
Monte Carlo simulation of the influence of solvent on nucleic acid base associations.
Topics: Adenine; Base Composition; Carbon Tetrachloride; Computer Simulation; Cytosine; Guanine; Hydrogen Bonding; Models, Chemical; Models, Molecular; Monte Carlo Method; Nucleic Acid Conformation; Nucleic Acids; Solutions; Solvents; Uracil; Water | 1984 |
Potential-derived point-charge model study of electrostatic interactions in DNA base components.
Topics: Adenine; Base Composition; Cytosine; DNA; Electrochemistry; Guanine; Hydrogen Bonding; Models, Chemical; Models, Molecular; Nucleic Acid Conformation; Static Electricity; Thymine | 1984 |
Transport of extraterrestrial biomolecules to the Earth: problem of thermal stability.
Topics: Adenine; Amino Acids; Cosmic Dust; Cytosine; Earth, Planet; Evolution, Chemical; Extraterrestrial Environment; Guanine; Hot Temperature; Meteoroids; Origin of Life; Oxidation-Reduction; Particle Size; Piperazines; Uracil | 1999 |
Prebiotic synthesis of adenine and amino acids under Europa-like conditions.
Topics: Adenine; Amino Acids; Cyanides; Evolution, Chemical; Exobiology; Freezing; Guanine; Hydrogen Cyanide; Ice; Jupiter | 2000 |
Nonenzymatic oligomerization reactions on templates containing inosinic acid or diaminopurine nucleotide residues.
Topics: 2-Aminopurine; Adenine; Adenosine; Adenosine Monophosphate; Base Pairing; Cytidine Monophosphate; Cytosine; DNA Primers; Evolution, Chemical; Evolution, Molecular; Exobiology; Guanine; Inosine Monophosphate; RNA; Templates, Genetic; Uracil; Uridine Monophosphate | 1999 |
Genetic polymorphisms in the androgen receptor and type II 5 alpha-reductase genes in prostate enlargement.
Topics: Adenine; Aged; Cholestenone 5 alpha-Reductase; Cytosine; Guanine; Humans; Male; Middle Aged; Oxidoreductases; Polymorphism, Genetic; Prostatic Hyperplasia; Receptors, Androgen; Trinucleotide Repeats | 2001 |
Synthesis and characterization of nucleosides and oligonucleotides with a benzo[a]pyren-6-ylmethyl adduct at adenine N6 or guanine N2.
Topics: Adenine; Benzo(a)pyrene; Benzopyrenes; DNA Adducts; Guanine; Mutagens; Nucleosides; Oligonucleotides; Oxidation-Reduction; Structure-Activity Relationship | 2001 |
Hydration heat capacity of nucleic acid constituents determined from the random network model.
Topics: Adenine; Cysteine; Deoxyribose; Guanine; Hot Temperature; Hydrogen Bonding; Models, Chemical; Neural Networks, Computer; Nucleic Acids; Phosphates; Ribose; Thermodynamics; Thymine; Uracil; Water | 2001 |
Molecular cloning and functional analysis of the MutY homolog of Deinococcus radiodurans.
Topics: Adenine; Amino Acid Sequence; Bacterial Proteins; Base Pair Mismatch; Carbon-Oxygen Lyases; Cloning, Molecular; Deoxyribonuclease IV (Phage T4-Induced); DNA Glycosylases; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; Edetic Acid; Escherichia coli; Escherichia coli Proteins; Genetic Complementation Test; Guanine; Kinetics; Molecular Sequence Data; Mutation; N-Glycosyl Hydrolases; Sequence Homology, Amino Acid; Sodium Chloride; Thermus | 2001 |
Proton exchange and local stability in a DNA triple helix containing a G.TA triad.
Topics: Adenine; Base Pairing; DNA; Guanine; Magnetic Resonance Spectroscopy; Oligodeoxyribonucleotides; Protons; Thymine | 2001 |
Bond energies and attachments sites of sodium and potassium cations to DNA and RNA nucleic acid bases in the gas phase.
Topics: Adenine; Cations; Cytosine; DNA; Guanine; Models, Chemical; Models, Molecular; Potassium; RNA; Sodium; Thermodynamics; Thymine; Uracil | 2001 |
On the molecular discrimination between adenine and guanine by proteins.
Topics: Adenine; Binding Sites; Computational Biology; Conserved Sequence; Databases, Protein; Guanine; Hydrogen Bonding; Ligands; Models, Molecular; Protein Binding; Protein Folding; Protein Structure, Tertiary; Proteins; Structure-Activity Relationship; Substrate Specificity; Thermodynamics | 2001 |
Selective interaction of tirapazamine with DNA bases and DNA. A comparison of cyclic voltammetry and electrolysis techniques.
Topics: Adenine; Conductometry; Cytosine; DNA; Electrolysis; Escherichia coli; Guanine; Oxidation-Reduction; Spectrophotometry, Ultraviolet; Thymine; Tirapazamine; Triazines | 2001 |
Guanine nucleosides and Jurkat cell death: roles of ATP depletion and accumulation of deoxyribonucleotides.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Apoptosis; Cell Nucleus; Cell Separation; Deoxyadenosines; Deoxyguanosine; Deoxyribonucleotides; Flow Cytometry; Guanine; Guanosine; Guanosine Triphosphate; Humans; Jurkat Cells; K562 Cells; Leukocytes; Time Factors | 2001 |
5-HT2A receptor gene promoter polymorphism -1438A/G and bipolar disorder.
Topics: Adenine; Adult; Asian People; Bipolar Disorder; Chi-Square Distribution; Female; Gene Frequency; Genotype; Guanine; Humans; Korea; Male; Polymerase Chain Reaction; Polymorphism, Genetic; Promoter Regions, Genetic; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Reference Values | 2001 |
Identification and characterization of a divalent metal ion-dependent cleavage site in the hammerhead ribozyme.
Topics: Adenine; Base Sequence; Binding Sites; Cadmium; Cations, Divalent; Cations, Monovalent; Cobalt; Guanine; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Lead; Manganese; Molecular Sequence Data; Nickel; RNA, Catalytic; Substrate Specificity; Zinc | 2001 |
Potential of (GATA)n microsatellites from rice for inter- and intra-specific variability studies.
Topics: Adenine; Alleles; Cloning, Molecular; Cluster Analysis; DNA, Plant; Genes, Plant; Genetic Markers; Genetic Variation; Genotype; Guanine; Immunity, Innate; Microsatellite Repeats; Molecular Sequence Data; Oryza; Plant Diseases; Polymorphism, Genetic; Sequence Analysis, DNA; Species Specificity; Thymine | 2001 |
The negative ion states of molecules: adenine and guanine.
Topics: Adenine; Anions; Base Pairing; DNA; DNA Damage; Electrochemistry; Electrons; Guanine; Ions; Models, Chemical; Models, Molecular; Models, Theoretical; Molecular Structure | 2001 |
A cis-acting element known to block 3' mRNA degradation enhances expression of polyA-minus mRNA in wild-type yeast cells and phenocopies a ski mutant.
Topics: 3' Untranslated Regions; Adenine; Fungal Proteins; Gene Expression Regulation, Fungal; Guanine; Kinetics; Mutagenesis; Nuclear Proteins; Oligoribonucleotides; Poly A; Poly(A)-Binding Proteins; Regulatory Sequences, Nucleic Acid; RNA-Binding Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2001 |
Structural basis of pyrimidine specificity in the MS2 RNA hairpin-coat-protein complex.
Topics: Adenine; Bromouracil; Capsid; Capsid Proteins; Guanine; Levivirus; Models, Molecular; Nucleic Acid Conformation; Protein Conformation; Pyrimidines; RNA-Binding Proteins; RNA, Viral; Thiouracil | 2001 |
Recognition templates for predicting adenylate-binding sites in proteins.
Topics: Adenine; Adenosine Monophosphate; Adenosine Triphosphate; Binding Sites; Computational Biology; Computer Simulation; Consensus Sequence; Databases, Protein; Flavin-Adenine Dinucleotide; Guanine; Guanosine Monophosphate; Guanosine Triphosphate; Hydrogen Bonding; Ligands; Models, Molecular; NAD; Protein Binding; Protein Conformation; Protein Interaction Mapping; Proteins; Substrate Specificity; Thermodynamics | 2001 |
A comprehensive model for the allosteric regulation of mammalian ribonucleotide reductase. Functional consequences of ATP- and dATP-induced oligomerization of the large subunit.
Topics: Adenine; Adenosine Triphosphate; Allosteric Site; Animals; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Dimerization; DNA; Dose-Response Relationship, Drug; Escherichia coli; Guanine; Kinetics; Ligands; Light; Mice; Models, Chemical; Models, Molecular; Models, Statistical; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Ribonucleotide Reductases; Scattering, Radiation | 2002 |
Electrochemical oxidation mechanism of guanine and adenine using a glassy carbon microelectrode.
Topics: Adenine; Electrochemistry; Guanine; Hydrogen-Ion Concentration; Microelectrodes; Oxidation-Reduction | 2002 |
Parallel and antiparallel G*G.C base triplets in pur*pur.pyr triple helices formed with (GA) third strands.
Topics: Adenine; Base Sequence; Carbohydrate Conformation; Cations, Divalent; Cytosine; DNA; Guanine; Magnesium; Nucleic Acid Conformation; Nucleic Acid Denaturation; Oligonucleotides; Purines; Pyrimidines; Sodium; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Temperature; Trinucleotide Repeats | 2001 |
Recognition of the rotavirus mRNA 3' consensus by an asymmetric NSP3 homodimer.
Topics: Adenine; Binding Sites; Consensus Sequence; Cytidine; Dimerization; Guanine; Humans; Hydrogen Bonding; Molecular Sequence Data; Protein Structure, Tertiary; RNA, Messenger; RNA, Viral; Rotavirus; Rotavirus Infections; Sequence Homology, Amino Acid; Viral Nonstructural Proteins; Virus Replication | 2002 |
Long-range oxidative damage in duplex DNA: the effect of bulged G in a G-C tract and tandem G/A mispairs.
Topics: Adenine; Anthraquinones; Base Pair Mismatch; Cations; Circular Dichroism; Conserved Sequence; DNA; DNA Damage; DNA Repair; DNA-Formamidopyrimidine Glycosylase; Electron Transport; Electrons; GC Rich Sequence; Guanine; N-Glycosyl Hydrolases; Nucleic Acid Conformation; Nucleic Acid Denaturation; Oxidative Stress; Photolysis; Tandem Repeat Sequences; Temperature | 2002 |
Toward electrochemical resolution of two genes on one electrode: using 7-deaza analogues of guanine and adenine to prepare PCR products with differential redox activity.
Topics: Adenine; Bacterial Proteins; Carrier Proteins; DNA; Electrochemistry; Electrodes; Escherichia coli; Guanine; Hexosyltransferases; Muramoylpentapeptide Carboxypeptidase; Oxidation-Reduction; Penicillin-Binding Proteins; Peptidyl Transferases; Polymerase Chain Reaction | 2002 |
Lack of impact of CYP1A2 genetic polymorphism (C/A polymorphism at position 734 in intron 1 and G/A polymorphism at position -2964 in the 5'-flanking region of CYP1A2) on the plasma concentration of haloperidol in smoking male Japanese with schizophrenia.
Topics: 5' Flanking Region; Adenine; Adult; Aged; Antipsychotic Agents; Cytochrome P-450 CYP1A2; Cytosine; Enzyme Induction; Guanine; Haloperidol; Humans; Introns; Japan; Male; Middle Aged; Point Mutation; Polymorphism, Genetic; Schizophrenia; Smoking | 2002 |
Novel cross-strand three-purine stack of the highly conserved 5'-GA/AAG-5' internal loop at the 3'-end termini of Parvovirus genomes.
Topics: Adenine; Base Sequence; Conserved Sequence; DNA, Single-Stranded; DNA, Viral; Genome, Viral; Guanine; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Parvovirus; Protons; Purines; Telomere; Temperature; Thermodynamics | 2001 |
A late onset variant of ataxia-telangiectasia with a compound heterozygous genotype, A8030G/7481insA.
Topics: Adenine; Adult; Ataxia Telangiectasia; Female; Genetic Carrier Screening; Genotype; Guanine; Humans; Male; Middle Aged; Mutagenesis, Insertional; Pedigree; Point Mutation | 2002 |
A novel allelic variant of the human TSG-6 gene encoding an amino acid difference in the CUB module. Chromosomal localization, frequency analysis, modeling, and expression.
Topics: Adenine; Alanine; Alleles; Amino Acid Sequence; Amino Acid Substitution; Arginine; Base Sequence; Cell Adhesion Molecules; Chromosome Mapping; Chromosomes, Human, Pair 2; Gene Frequency; Genetic Linkage; Genetic Variation; Glutamine; Guanine; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Osteoarthritis; Polymorphism, Single Nucleotide; Protein Conformation; Tumor Necrosis Factor-alpha | 2002 |
The A8296G mtDNA mutation associated with several mitochondrial diseases does not cause mitochondrial dysfunction in cybrid cell lines.
Topics: Adenine; Cell Fusion; Cell Line; DNA, Mitochondrial; Female; Fibroblasts; Guanine; Humans; Hybrid Cells; Male; MERRF Syndrome; Mitochondria; Mitochondrial Diseases; Mutation | 2002 |
Replication-associated repair of adenine:8-oxoguanine mispairs by MYH.
Topics: Adenine; Animals; Base Pair Mismatch; Cell Line; DNA Glycosylases; DNA Repair; DNA Replication; Guanine; Mice; Models, Biological; Mutation; N-Glycosyl Hydrolases; Proliferating Cell Nuclear Antigen | 2002 |
Significance of a polymorphism (G-->A transition) in the -75 position of the apolipoprotein A-I gene promoter on serum high density lipoprotein-cholesterol levels in Japanese hyperlipidemic subjects.
Topics: Adenine; Apolipoprotein A-I; Carrier Proteins; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Glycoproteins; Guanine; Humans; Hyperlipidemias; Polymorphism, Genetic; Promoter Regions, Genetic | 2001 |
Intrinsic conformational energetics associated with the glycosyl torsion in DNA: a quantum mechanical study.
Topics: Adenine; Crystallography, X-Ray; DNA; Guanine; Models, Molecular; Nucleic Acid Conformation; Nucleosides; Quantum Theory | 2002 |
Heat-induced formation of reactive oxygen species and 8-oxoguanine, a biomarker of damage to DNA.
Topics: Adenine; Biomarkers; DNA; DNA Damage; Guanine; Hot Temperature; Hydrogen Peroxide; Kinetics; Oxidative Stress; Reactive Oxygen Species | 2002 |
Evidence for a common molecular basis for sequence recognition of N3-guanine and N3-adenine DNA adducts involving the covalent bonding reaction of (+)-CC-1065.
Topics: Adenine; Antibiotics, Antineoplastic; Base Sequence; Catalysis; DNA; DNA Adducts; Duocarmycins; Guanine; Hydrogen Bonding; Hydrogen-Ion Concentration; Indoles; Leucomycins; Magnetic Resonance Spectroscopy; Models, Molecular; Nucleic Acid Conformation; Oligonucleotides | 2002 |
Relationship of the tumor necrosis factor-alpha -308 A/G promoter polymorphism with insulin sensitivity and abdominal fat distribution in Japanese patients with type 2 diabetes mellitus.
Topics: Abdomen; Adenine; Adipose Tissue; Asian People; Body Mass Index; Diabetes Mellitus, Type 2; DNA Primers; Female; Guanine; Humans; Insulin Resistance; Japan; Male; Middle Aged; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Promoter Regions, Genetic; Reference Values; Tumor Necrosis Factor-alpha | 2002 |
Intercalators. 1. Nature of stacking interactions between intercalators (ethidium, daunomycin, ellipticine, and 4',6-diaminide-2-phenylindole) and DNA base pairs. Ab initio quantum chemical, density functional theory, and empirical potential study.
Topics: Adenine; Base Pairing; Cytosine; DNA; Guanine; Intercalating Agents; Models, Chemical; Models, Molecular; Molecular Structure; Nucleic Acid Conformation; Quantum Theory; Thermodynamics; Thymine | 2002 |
The effect of DNA damage on the formation of protein/DNA complexes.
Topics: Adenine; Binding Sites; DNA; DNA Damage; DNA-Binding Proteins; Guanine; Promoter Regions, Genetic; Protein Binding; Transcription Factor AP-1 | 2002 |
Polymorphism in the Calpain 10 gene influences glucose metabolism in human fat cells.
Topics: Adenine; Adipocytes; Adipose Tissue; Calpain; DNA Primers; Female; Genotype; Glucose; Glucose Transporter Type 4; Guanine; Humans; Lipolysis; Monosaccharide Transport Proteins; Muscle Proteins; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Reference Values; RNA, Messenger; Transcription, Genetic | 2002 |
Trinucleotide repeats in 202 families with ataxia: a small expanded (CAG)n allele at the SCA17 locus.
Topics: Adenine; Adult; Aged; Alleles; Brazil; Cytosine; Female; Guanine; Heterozygote; Humans; Male; Middle Aged; Nerve Tissue Proteins; Polymerase Chain Reaction; Portugal; Spinocerebellar Ataxias; Trinucleotide Repeat Expansion | 2002 |
Mechanisms of apoptosis induced by purine nucleosides in astrocytes.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Apoptosis; Astrocytes; Carrier Proteins; Cells, Cultured; Central Nervous System; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Guanine; Guanosine; Hypoxanthine; Inosine; Male; Purine Nucleosides; Purinergic P1 Receptor Antagonists; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A3; Receptors, Purinergic P1; RNA, Messenger | 2002 |
Different substrate recognition motifs of human and trypanosome nucleobase transporters. Selective uptake of purine antimetabolites.
Topics: Adenine; Animals; Antimetabolites; Carrier Proteins; Erythrocytes; Guanine; Humans; Hydrogen Bonding; Hypoxanthine; Membrane Proteins; Nucleoside Transport Proteins; Protein Binding; Protein Conformation; Purines; Structure-Activity Relationship; Trypanosoma brucei brucei | 2002 |
On the competition of the purine bases, functionalities of peptide side chains, and protecting agents for the coordination sites of dicationic cisplatin derivatives.
Topics: Adenine; Antineoplastic Agents; Cisplatin; DNA Adducts; Guanine; Imidazoles; Ligands; Molecular Structure; Peptides; Static Electricity | 2002 |
Is molecular oxygen, O(2), the reactive radical behind oxidations of (aut)oxidable agents to which the bases of DNA belong?
Topics: Adenine; DNA; Dopamine; Electrons; Free Radicals; Guanine; Hydrogen Peroxide; Models, Biological; Models, Chemical; Oxygen; RNA; Serotonin; Xanthine | 2002 |
Comparative study of permanganate oxidation reactions of nucleotide bases by spectroscopy.
Topics: Adenine; Cytosine; Guanine; Kinetics; Manganese Compounds; Methods; Oxidation-Reduction; Oxides; Potassium Permanganate; Purines; Pyrimidines; Spectrum Analysis; Thymine; Uracil | 2002 |
A model for the generation of multiple A to G transitions in the human respiratory syncytial virus genome: predicted RNA secondary structures as substrates for adenosine deaminases that act on RNA.
Topics: Adenine; Adenosine Deaminase; Antibodies, Monoclonal; Antibodies, Viral; Base Sequence; Genome, Viral; Guanine; HN Protein; Models, Genetic; Molecular Sequence Data; Nucleic Acid Conformation; Point Mutation; Respiratory Syncytial Virus, Human; RNA, Viral; Viral Envelope Proteins | 2002 |
Studies on the interaction between Cd(2+) ions and nucleobases and nucleotides.
Topics: Adenine; Adenosine Monophosphate; Animals; Binding Sites; Cadmium; Deoxyguanine Nucleotides; DNA; DNA Damage; Guanine; Humans; In Vitro Techniques; Molecular Structure; Reactive Oxygen Species; Spectrophotometry; Spectroscopy, Fourier Transform Infrared | 2002 |
A change in the last base of BRCA1 exon 23, 5586G-->A, results in abnormal RNA splicing.
Topics: Adenine; Alternative Splicing; Base Sequence; Exons; Female; Genes, BRCA1; Guanine; Humans; Molecular Sequence Data; Point Mutation; RNA, Messenger | 2002 |
CTLA-4 49 A/G dimorphism and type 1 diabetes susceptibility: a French case-control study and segregation analysis. Evidence of a maternal effect.
Topics: Adenine; Adolescent; Adult; Aged; Antigens, CD; Antigens, Differentiation; Case-Control Studies; Child; Child, Preschool; CTLA-4 Antigen; Diabetes Mellitus, Type 1; Female; France; Gene Frequency; Genomic Imprinting; Guanine; Humans; Male; Minisatellite Repeats; Polymorphism, Single Nucleotide | 2002 |
Ab initio GB study of methylation reaction of adenine, cytosine, guanine, and thymine by methanediazonium ion.
Topics: Adenine; Cytosine; Diazomethane; DNA Methylation; Guanine; Models, Chemical; Molecular Structure; Thymine | 2002 |
Complex neurologic syndrome associated with the G1606A mutation of mitochondrial DNA.
Topics: Adenine; Adult; Brain; DNA, Mitochondrial; Guanine; Humans; Male; Muscle, Skeletal; Mutation; Nervous System Diseases; RNA, Transfer; Syndrome | 2002 |
The cockayne syndrome group B gene product is involved in cellular repair of 8-hydroxyadenine in DNA.
Topics: Adenine; DNA Helicases; DNA Repair; DNA Repair Enzymes; Gamma Rays; Guanine; Humans; Poly-ADP-Ribose Binding Proteins | 2002 |
Molecular recognition by the Candida albicans group I intron: tertiary interactions with an imino G.A pair facilitate binding of the 5' exon and lower the KM for guanosine.
Topics: Adenine; Binding Sites; Candida albicans; Exons; Guanine; Guanosine; Inosine; Introns; Kinetics; Models, Molecular; Molecular Mimicry; Nucleic Acid Conformation; RNA, Catalytic; Thermodynamics | 2002 |
Two 1 : 1 binding modes for distamycin in the minor groove of d(GGCCAATTGG).
Topics: Adenine; Amides; Base Pairing; Binding Sites; Crystallography, X-Ray; Distamycins; Guanine; Hydrogen Bonding; Models, Molecular; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Quantum Theory; Thymidine | 2002 |
Effects of bile acids on base hydroxylation in a model of human colonic mucosal DNA.
Topics: Adenine; Animals; Cattle; Chenodeoxycholic Acid; Colon; Colonic Neoplasms; Deoxycholic Acid; DNA; DNA Damage; Gas Chromatography-Mass Spectrometry; Gastrointestinal Agents; Guanine; Humans; Hydroxylation; Intestinal Mucosa; Models, Chemical; Reactive Oxygen Species; Salicylates; Thymus Gland | 2002 |
Electrochemical evaluation of rhodium dimer-DNA interactions.
Topics: Adenine; Anticarcinogenic Agents; Biosensing Techniques; Dimerization; DNA; Electrochemistry; Guanine; Ligands; Organometallic Compounds; Oxidation-Reduction; Rhodium | 2002 |
An amplification and ligation-based method to scan for unknown mutations in DNA.
Topics: Adenine; Antigens, Nuclear; Ataxia Telangiectasia Mutated Proteins; Bacteriophage T4; Base Pair Mismatch; Cell Cycle Proteins; DNA Helicases; DNA Ligases; DNA Mutational Analysis; DNA-Binding Proteins; Genes, p53; Guanine; Humans; Ku Autoantigen; Ligases; Mutation; Nuclear Proteins; Nucleic Acid Amplification Techniques; Nucleic Acid Heteroduplexes; Point Mutation; Polymorphism, Single Nucleotide; Protein Serine-Threonine Kinases; RNA Ligase (ATP); Tumor Suppressor Proteins; Viral Proteins | 2002 |
Association of the myeloperoxidase -463G-->A polymorphism with development of atrophy in Helicobacter pylori-infected gastritis.
Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; Female; Gastric Mucosa; Gastritis, Atrophic; Genotype; Guanine; Helicobacter Infections; Helicobacter pylori; Humans; Male; Middle Aged; Peroxidase; Polymorphism, Single Nucleotide | 2002 |
Base excision repair of adenine/8-oxoguanine mispairs by an aphidicolin-sensitive DNA polymerase in human cell extracts.
Topics: Adenine; Aphidicolin; Base Pair Mismatch; Base Pairing; Cell Extracts; DNA; DNA Primers; DNA Repair; Drug Resistance; Enzyme Inhibitors; Guanine; HeLa Cells; Humans; Nucleic Acid Synthesis Inhibitors | 2002 |
The adenine phosphoribosyltransferase from Giardia lamblia has a unique reaction mechanism and unusual substrate binding properties.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine Monophosphate; Amino Acid Sequence; Animals; Catalysis; Cloning, Molecular; Giardia lamblia; Guanine; Kinetics; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan | 2002 |
Closed site complexes of adenine phosphoribosyltransferase from Giardia lamblia reveal a mechanism of ribosyl migration.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine Monophosphate; Amino Acid Sequence; Animals; Arginine; Binding Sites; Catalysis; Catalytic Domain; Cloning, Molecular; Giardia lamblia; Guanine; Hydrogen Bonding; Kinetics; Ligands; Magnesium; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan | 2002 |
Characterization of the in vitro kinase activity of a partially purified soluble GST/JAK2 fusion protein.
Topics: Adenine; Animals; Biotinylation; Catalysis; Cell Line; Chromatography, Affinity; DNA-Binding Proteins; DNA, Complementary; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Glutathione Transferase; Guanine; Insecta; Janus Kinase 2; Models, Chemical; Peptides; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Rats; Recombinant Fusion Proteins; STAT1 Transcription Factor; Trans-Activators; Tyrosine; Tyrphostins | 2002 |
A polymorphism in the human agouti-related protein is associated with late-onset obesity.
Topics: Adenine; Adult; Age of Onset; Agouti-Related Protein; Animals; Exons; Female; Genotype; Guanine; Humans; Intercellular Signaling Peptides and Proteins; Male; Mice; Middle Aged; Obesity; Polymorphism, Single Nucleotide; Proteins | 2002 |
Informatics. The genome chose its alphabet with care.
Topics: Adenine; Base Pair Mismatch; Base Pairing; Computational Biology; Cytosine; Genetic Code; Genome; Guanine; Thymine | 2002 |
Thermal desorption behavior and binding properties of DNA bases and nucleosides on gold.
Topics: Adenine; Adsorption; Cytosine; DNA; Gold; Guanine; Hot Temperature; Nucleosides; Spectrophotometry, Infrared; Surface Properties; Thermodynamics; Thymine | 2002 |
The GAAA tetraloop-receptor interaction contributes differentially to folding thermodynamics and kinetics for the P4-P6 RNA domain.
Topics: Adenine; Animals; Electrophoresis, Polyacrylamide Gel; Guanine; Introns; Kinetics; Models, Chemical; Nucleic Acid Conformation; Nucleic Acid Denaturation; RNA, Catalytic; Spectrometry, Fluorescence; Static Electricity; Tetrahymena; Thermodynamics | 2002 |
Formation of adenine-N3/guanine-N7 cross-link in the reaction of trans-oriented platinum substrates with dinucleotides.
Topics: Adenine; Chromatography, High Pressure Liquid; Cisplatin; Cross-Linking Reagents; Deoxyadenine Nucleotides; Deoxyguanosine; DNA; Guanine; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular | 2002 |
Z-isomers of 2-hydroxymethylcyclopropylidenemethyl adenine (synadenol) and guanine (synguanol) are active against ganciclovir- and foscarnet-resistant human cytomegalovirus UL97 mutants.
Topics: Adenine; Antiviral Agents; Cyclopropanes; Cytomegalovirus; Cytomegalovirus Infections; Drug Resistance, Viral; Foscarnet; Ganciclovir; Guanine; Humans; Immunocompromised Host; Phosphotransferases (Alcohol Group Acceptor) | 2002 |
Electrochemical biosensor for the interaction of DNA with the alkylating agent 4,4'-dihydroxy chalcone based on guanine and adenine signals.
Topics: Adenine; Biosensing Techniques; Chalcone; Chalcones; DNA; Electrochemistry; Guanine | 2002 |
Low prevalence of the substitution of adenine to guanine at the 3243 nucleotide position of mitochondrial DNA (MtDNA) among Indonesian diabetic subjects.
Topics: Adenine; Diabetes Mellitus; DNA, Mitochondrial; Guanine; Humans; Indonesia; Polymorphism, Single Nucleotide; Prevalence; RNA; RNA, Mitochondrial; RNA, Transfer, Leu | 2002 |
Resistance to the macrolide antibiotic tylosin is conferred by single methylations at 23S rRNA nucleotides G748 and A2058 acting in synergy.
Topics: Adenine; Binding Sites; DNA Primers; Drug Resistance, Bacterial; Escherichia coli; Genes, Bacterial; Guanine; Methylation; RNA, Ribosomal, 23S; Streptomyces; Tylosin | 2002 |
Pyrazolylborate-zinc-nucleobase-complexes, 2:(1) preparations and structures of Tp(Cum,Me)Zn and Tp(Ph,Me)Zn complexes.
Topics: Adenine; Borates; Cytosine; Guanine; Hydrogen Bonding; Hypoxanthines; Molecular Structure; Nucleosides; Organometallic Compounds; Purines; Pyrazoles; Pyrimidines; Spectrophotometry, Infrared; Thymine; Uracil; Xanthines; Zinc | 2002 |
Accumulation of somatic mutation in mitochondrial DNA extracted from peripheral blood cells in diabetic patients.
Topics: Adenine; Adolescent; Adult; Age of Onset; Aged; Base Sequence; Body Mass Index; Diabetes Mellitus, Type 2; DNA; DNA Primers; DNA, Mitochondrial; Female; Guanine; Humans; Infant, Newborn; Male; Middle Aged; Point Mutation; Reference Values | 2002 |
A dimeric mechanism for contextual target recognition by MutY glycosylase.
Topics: Acrylamides; Adenine; Base Pair Mismatch; Binding Sites; Dimerization; DNA; DNA Damage; DNA Glycosylases; DNA Repair; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Guanine; Models, Chemical; N-Glycosyl Hydrolases; Oligonucleotides; Thermodynamics; Time Factors | 2003 |
Far-infrared vibrational modes of DNA components studied by terahertz time-domain spectroscopy.
Topics: Adenine; Crystallography; Cytosine; DNA; Electromagnetic Phenomena; Guanine; Hydrogen Bonding; Microwaves; Models, Molecular; Molecular Conformation; Nucleosides; Nucleotides; Optics and Photonics; Refractometry; Spectrophotometry, Infrared; Spectrum Analysis; Thymine; Vibration | 2002 |
The polymorphism of monocyte chemoattractant protein-1 is associated with the renal disease of SLE.
Topics: 5' Flanking Region; Adenine; Adult; Chemokine CCL2; Disease Progression; Female; Gene Expression Regulation; Genotype; Guanine; Homozygote; Humans; Kidney Diseases; Lupus Erythematosus, Systemic; Lupus Nephritis; Male; Polymorphism, Genetic | 2002 |
Effects of endogenous DNA base lesions on transcription elongation by mammalian RNA polymerase II. Implications for transcription-coupled DNA repair and transcriptional mutagenesis.
Topics: Adenine; Adenosine Triphosphate; Cytidine Triphosphate; DNA; DNA Repair; DNA, Circular; Guanine; Guanosine; HeLa Cells; Humans; Models, Genetic; Mutagenesis; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA Polymerase II; Time Factors; Transcription, Genetic | 2003 |
Base excision repair and nucleotide excision repair contribute to the removal of N-methylpurines from active genes.
Topics: Adenine; Animals; Cells, Cultured; DNA Damage; DNA Glycosylases; DNA Repair; DNA Replication; Guanine; Mice; Mice, Knockout; N-Glycosyl Hydrolases; Phenotype; Pyrimidine Dimers; Tetrahydrofolate Dehydrogenase; Transcription, Genetic | 2002 |
Tumor necrosis factor-alpha +489G/A gene polymorphism is associated with chronic obstructive pulmonary disease.
Topics: Adenine; Adult; Aged; Aged, 80 and over; Alleles; Female; Genotype; Guanine; Humans; Male; Middle Aged; Netherlands; Polymorphism, Genetic; Pulmonary Disease, Chronic Obstructive; Pulmonary Emphysema; Radiography; Tumor Necrosis Factor-alpha | 2002 |
[Separation and determination of purine bases and pyrimidine bases from nucleic acid hydrolysis by HPLC on BDS column].
Topics: Adenine; Chromatography, High Pressure Liquid; Cytosine; Guanine; Hypoxanthine; Nucleic Acids; Purines; Pyrimidines; Thymine; Uracil; Yeasts | 2000 |
[Determination of the base contents of liver DNA of rats by reversed-phase high performance liquid chromatography].
Topics: Adenine; Altitude; Animals; Chromatography, High Pressure Liquid; Cytosine; DNA; DNA Methylation; Guanine; Liver; Rats; Thymine | 2002 |
The pathogenic A3243G mutation in human mitochondrial tRNALeu(UUR) decreases the efficiency of aminoacylation.
Topics: Acylation; Adenine; Base Sequence; Cell Line; Cytosine; Guanine; Humans; Leucine-tRNA Ligase; MELAS Syndrome; Molecular Sequence Data; Mutation; RNA; RNA, Mitochondrial; RNA, Transfer, Leu; Thymine | 2003 |
Null mutations in the N-acetylglutamate synthase gene associated with acute neonatal disease and hyperammonemia.
Topics: Acetyltransferases; Adenine; Amino-Acid N-Acetyltransferase; Base Sequence; Denmark; Female; Genetic Diseases, Inborn; Guanine; Hispanic or Latino; Homozygote; Humans; Hyperammonemia; Infant; Infant, Newborn; Male; Molecular Sequence Data; Mutation; Polymorphism, Restriction Fragment Length; Sequence Analysis, DNA; Tryptophan; White People | 2003 |
The effect of tautomeric constant on the specificity of nucleotide incorporation during DNA replication: support for the rare tautomer hypothesis of substitution mutagenesis.
Topics: Adenine; Base Pairing; Crystallography, X-Ray; Deoxyribonucleosides; Deoxyribonucleotides; DNA; DNA Polymerase I; DNA Primers; DNA Replication; Guanine; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Molecular Structure; Mutagenesis; Nucleic Acid Conformation; Nucleic Acid Heteroduplexes; Oxazines; Pyrimidines | 2003 |
Platinum cross-linking of adenines and guanines on the quadruplex structures of the AG3(T2AG3)3 and (T2AG3)4 human telomere sequences in Na+ and K+ solutions.
Topics: Adenine; Base Sequence; Binding Sites; Cross-Linking Reagents; Electrophoresis, Polyacrylamide Gel; Guanine; Humans; Nucleic Acid Conformation; Oligonucleotides; Platinum; Potassium; Repetitive Sequences, Nucleic Acid; Sodium; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Telomere | 2003 |
Insight into the functional consequences of inherited variants of the hMYH adenine glycosylase associated with colorectal cancer: complementation assays with hMYH variants and pre-steady-state kinetics of the corresponding mutated E.coli enzymes.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenine; Adenomatous Polyposis Coli; Base Pair Mismatch; Binding Sites; Colorectal Neoplasms; Deoxyadenosines; Deoxyguanosine; DNA Glycosylases; DNA Primers; DNA Repair; Escherichia coli; Genes, APC; Genetic Complementation Test; Genetic Variation; Guanine; Heterozygote; Humans; In Vitro Techniques; Kinetics; Mutagenesis, Site-Directed; N-Glycosyl Hydrolases; Polymerase Chain Reaction | 2003 |
Association of the -1087 IL 10 gene polymorphism with severe chronic periodontitis in Swedish Caucasians.
Topics: Adenine; Adult; Aged; Alleles; Alveolar Bone Loss; Chi-Square Distribution; Chronic Disease; Confidence Intervals; Female; Gene Frequency; Genotype; Guanine; Humans; Interleukin-10; Male; Middle Aged; Odds Ratio; Periodontitis; Periodontium; Polymorphism, Genetic; Smoking; Sweden; White People | 2003 |
Mammalian 8-oxoguanine DNA glycosylase 1 incises 8-oxoadenine opposite cytosine in nuclei and mitochondria, while a different glycosylase incises 8-oxoadenine opposite guanine in nuclei.
Topics: Adenine; Animals; Base Pairing; Base Sequence; Cell Line, Transformed; Cell Nucleus; Cytosine; DNA; DNA Repair; DNA-Formamidopyrimidine Glycosylase; Fibroblasts; Guanine; Humans; Liver; Magnesium; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; N-Glycosyl Hydrolases; Nucleic Acid Conformation; Oligonucleotides; Substrate Specificity | 2003 |
Increased abdominal obesity, insulin and glucose levels in nondiabetic subjects with a T29C polymorphism of the transforming growth factor-beta1 gene.
Topics: Abdomen; Adenine; Blood Glucose; Fasting; Gene Frequency; Genetic Variation; Guanine; Heterozygote; Homozygote; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Obesity; Polymorphism, Genetic; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2003 |
Primary fibroblasts of Cockayne syndrome patients are defective in cellular repair of 8-hydroxyguanine and 8-hydroxyadenine resulting from oxidative stress.
Topics: Adenine; Adult; Cell Line; Child; Child, Preschool; Cockayne Syndrome; DNA; DNA Damage; DNA Repair; Endonucleases; Exonucleases; Female; Guanine; Humans; Infant; Male; Oxidative Stress | 2003 |
A novel mutation A1270G of the EDA1 gene causing Tyr343Cys substitution in ectodysplasin-A in a family with anhidrotic ectodermal dysplasia.
Topics: Adenine; Amino Acid Substitution; Base Sequence; Cysteine; Ectodermal Dysplasia; Ectodysplasins; Exons; Female; Guanine; Humans; Infant; Male; Membrane Proteins; Mutation, Missense; Pedigree; Tyrosine | 2003 |
DNA homoduplexes containing no pyrimidine nucleotide.
Topics: Adenine; Base Pairing; Circular Dichroism; DNA; Electrophoresis, Polyacrylamide Gel; Guanine; Nucleic Acid Conformation; Nucleotides; Oligonucleotides; Pyrimidines; Tandem Repeat Sequences; Temperature | 2003 |
Extraction and purification of depurinated benzo[a]pyrene-adducted DNA bases from human urine by immunoaffinity chromatography coupled with HPLC and analysis by LC/quadrupole ion-trap MS.
Topics: Adenine; Adult; Benzopyrenes; Chromatography, High Pressure Liquid; Coal; DNA Adducts; Female; Guanine; Humans; Male; Mass Spectrometry; Smoking; Time Factors | 2003 |
Rational design of a DNA wire possessing an extremely high hole transport ability.
Topics: Adenine; DNA; Electric Conductivity; Guanine; Nanotechnology; Oxidation-Reduction | 2003 |
Direct electrochemistry of DNA, guanine and adenine at a nanostructured film-modified electrode.
Topics: Adenine; Adsorption; Animals; Cattle; DNA; Electrochemistry; Electrodes; Guanine; Hydrogen-Ion Concentration; Nucleic Acid Conformation; Organophosphates; Sensitivity and Specificity | 2003 |
Association of increased levels of fibrinogen and the -455G/A fibrinogen gene polymorphism with chronic periodontitis.
Topics: 5' Flanking Region; Adenine; Age Factors; Aged; Alleles; Analysis of Variance; Case-Control Studies; Chronic Disease; Confidence Intervals; Female; Fibrinogen; Genotype; Guanine; Homozygote; Humans; Male; Middle Aged; Odds Ratio; Periodontitis; Polymorphism, Genetic; Promoter Regions, Genetic; Sex Factors; Smoking | 2003 |
Fibrinogen is a marker for nephropathy and peripheral vascular disease in type 1 diabetes: studies of plasma fibrinogen and fibrinogen gene polymorphism in the DCCT/EDIC cohort.
Topics: Adenine; Adult; Albuminuria; Base Sequence; Biomarkers; Cohort Studies; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopathy; DNA Primers; Female; Fibrinogen; Guanine; Humans; Male; Peripheral Vascular Diseases; Polymorphism, Single Nucleotide; Regression Analysis | 2003 |
Decreased mitochondrial tRNALys steady-state levels and aminoacylation are associated with the pathogenic G8313A mitochondrial DNA mutation.
Topics: Acylation; Adenine; Base Sequence; Cell Line; DNA, Mitochondrial; Guanine; Humans; Mitochondria; Molecular Sequence Data; Nucleic Acid Conformation; Oxygen Consumption; Point Mutation; RNA; RNA, Mitochondrial; RNA, Transfer, Lys | 2003 |
Synthesis of antisense oligonucleotides with minimum depurination.
Topics: Adenine; Chromatography, High Pressure Liquid; Guanine; Hydrogen-Ion Concentration; Models, Chemical; Oligodeoxyribonucleotides; Oligonucleotides, Antisense; Purines; Trityl Compounds | 2003 |
Optimisation of the 10-23 DNAzyme-substrate pairing interactions enhanced RNA cleavage activity at purine-cytosine target sites.
Topics: 2-Aminopurine; Adenine; Base Pairing; Base Sequence; Catalysis; Cytosine; DNA, Catalytic; DNA, Single-Stranded; Guanine; Hydrogen Bonding; Kinetics; Nucleic Acid Conformation; RNA; RNA, Catalytic; Substrate Specificity | 2003 |
Two pathogenic mutations in the mitochondrial DNA tRNA Leu(UUR) gene (T3258C and A3280G) resulting in variable clinical phenotypes.
Topics: Acidosis, Lactic; Adenine; Adult; Biopsy; Cardiomyopathies; Cytosine; DNA, Mitochondrial; Female; Guanine; Humans; Male; Mitochondrial Encephalomyopathies; Muscle, Skeletal; Muscular Diseases; Mutation; Myocardium; Phenotype; Polymorphism, Genetic; RNA, Transfer, Leu; Stroke; Thymine | 2003 |
Increased variation in mtDNA in patients with familial sensorineural hearing impairment.
Topics: Adenine; Adult; Case-Control Studies; Cytosine; DNA, Mitochondrial; Europe; Female; Finland; Genetic Variation; Guanine; Haplotypes; Hearing Loss, Sensorineural; Humans; Male; Middle Aged; Polymorphism, Genetic; Thymine; White People | 2003 |
Analysis of the mouse transcriptome for genes involved in the function of the nervous system.
Topics: Adenine; Amino Acid Sequence; Animals; Brain Chemistry; Calcium; Calcium Channels; Chloride Channels; Cytosine; Databases, Genetic; Gene Library; Genes; GTP-Binding Proteins; Guanine; Humans; Mice; Molecular Sequence Data; Nervous System; Nervous System Physiological Phenomena; Neurodegenerative Diseases; Neurons; Neuropeptides; Phylogeny; Receptors, Cell Surface; Transcription, Genetic; Trinucleotide Repeat Expansion | 2003 |
Polymorphisms in the +252(A/G) lymphotoxin-alpha and the -308(A/G) tumor necrosis factor-alpha genes and susceptibility to chronic periodontitis in a Czech population.
Topics: Adenine; Adult; Case-Control Studies; Chronic Disease; Czech Republic; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Guanine; Humans; Introns; Lymphotoxin-alpha; Male; Middle Aged; Monte Carlo Method; Periodontitis; Polymorphism, Genetic; Promoter Regions, Genetic; Tumor Necrosis Factor-alpha; White People | 2003 |
Sequence context dependence of tandem guanine:adenine mismatch conformations in RNA: a continuum solvent analysis.
Topics: Adenine; Base Pair Mismatch; Base Sequence; Binding Sites; Computer Simulation; Energy Transfer; Guanine; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Sequence Alignment; Sequence Analysis, RNA; Solvents; Static Electricity; Tandem Repeat Sequences | 2003 |
Evidence of G-A/A-G pair, not A-G/G-A pair, in SECIS element.
Topics: 3' Untranslated Regions; Adenine; Base Pairing; Base Sequence; Codon; DNA; Guanine; Nucleic Acid Conformation; Nucleic Acid Denaturation; Proteins; Selenocysteine; Selenoproteins | 2001 |
Circular dichroism spectroscopy of conformers of (guanine + adenine) repeat strands of DNA.
Topics: Adenine; Circular Dichroism; DNA; Guanine; Repetitive Sequences, Nucleic Acid | 2003 |
A novel mitochondrial tRNA(Leu(UUR)) mutation in a patient with features of MERRF and Kearns-Sayre syndrome.
Topics: Adenine; Adult; Animals; Base Sequence; DNA, Mitochondrial; Electron Transport Complex IV; Guanine; Humans; Kearns-Sayre Syndrome; Male; MERRF Syndrome; Mitochondria, Muscle; Molecular Sequence Data; Muscle Fibers, Skeletal; Muscle, Skeletal; Mutation; Polymerase Chain Reaction; RNA; RNA, Mitochondrial; RNA, Transfer, Leu | 2003 |
Molecular genetic analysis for the Ae1 and A3 alleles.
Topics: ABO Blood-Group System; Adenine; Alleles; Base Sequence; Cloning, Molecular; Cytosine; Guanine; Humans; Introns; Molecular Biology; Molecular Sequence Data; Mutation; Mutation, Missense; Phenotype; Point Mutation; Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA; Taiwan; Thymine | 2003 |
A genetic and phenotypic analysis in Spanish spinal muscular atrophy patients with c.399_402del AGAG, the most frequently found subtle mutation in the SMN1 gene.
Topics: Adenine; Adult; Age of Onset; Child; Child, Preschool; Cyclic AMP Response Element-Binding Protein; Female; Genotype; Guanine; Heterozygote; Homozygote; Humans; Infant; Infant, Newborn; Male; Middle Aged; Muscular Atrophy, Spinal; Mutation; Nerve Tissue Proteins; Phenotype; RNA-Binding Proteins; Sequence Deletion; SMN Complex Proteins; Spain; Survival of Motor Neuron 1 Protein; Survival of Motor Neuron 2 Protein | 2003 |
The XRCC1 codon 399 Gln allele is associated with adenine to guanine p53 mutations in non-small cell lung cancer.
Topics: Adenine; Alleles; Carcinoma, Non-Small-Cell Lung; DNA-Binding Proteins; Female; Genes, p53; Genotype; Guanine; Humans; Lung Neoplasms; Male; Point Mutation; Polymorphism, Genetic; Smoking; X-ray Repair Cross Complementing Protein 1 | 2003 |
Myocardial infarction under the age of 36: prevalence of thrombophilic disorders.
Topics: Adenine; Adult; Antithrombin III; Case-Control Studies; Female; Guanine; Humans; Male; Mutation; Myocardial Infarction; Prevalence; Protein C; Protein S; Prothrombin; Risk Factors; Thrombophilia | 2003 |
The 2756A>G variant in the gene encoding methionine synthase: its relation with plasma homocysteine levels and risk of coronary heart disease in a Dutch case-control study.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenine; Case-Control Studies; Coronary Disease; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genetic Variation; Genotype; Guanine; Homocysteine; Humans; Middle Aged; Osmolar Concentration; Risk Factors; Vitamin B 12 | 2003 |
X-ray analyses of two DNA dodecamers containing N4-methoxy-cytosine paired with adenine or guanine.
Topics: Adenine; Base Pair Mismatch; Base Sequence; Crystallography, X-Ray; Cytosine; DNA; Guanine; Models, Molecular; Molecular Structure; Mutagenesis; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Static Electricity | 2000 |
Angiotensinogen gene variation and renoprotective efficacy of renin-angiotensin system blockade in IgA nephropathy.
Topics: Adenine; Adult; Alleles; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Cytoprotection; Female; Gene Frequency; Genetic Variation; Genotype; Glomerulonephritis, IGA; Guanine; Haplotypes; Humans; Kidney; Kidney Diseases; Male; Methionine; Middle Aged; Polymorphism, Genetic; Renin-Angiotensin System; Risk Factors; Threonine | 2003 |
Analysis of IL-12 p40 subunit gene and IFN-gamma G5644A polymorphisms in Idiopathic Pulmonary Fibrosis.
Topics: 3' Untranslated Regions; Adenine; Case-Control Studies; DNA Primers; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Guanine; Humans; Interferon-gamma; Interleukin-12; Interleukin-12 Subunit p40; Male; Middle Aged; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Protein Subunits; Pulmonary Fibrosis | 2003 |
Pelvic lymphocyst infection associated with maternally inherited diabetes mellitus.
Topics: Abdominal Pain; Adenine; Cysts; Deafness; Diabetes Complications; Diabetes Mellitus; DNA, Mitochondrial; Female; Fever; Guanine; Humans; Middle Aged; Mothers; Mutation; Pelvic Infection | 2003 |
Disposable electrochemical biosensor for the detection of the interaction between DNA and lycorine based on guanine and adenine signals.
Topics: Adenine; Amaryllidaceae Alkaloids; Biosensing Techniques; DNA; Electrochemistry; Electrodes; Guanine; Oxidation-Reduction; Phenanthridines; Poly G; Surface Properties | 2003 |
The nucleic acids of some insect viruses.
Topics: Adenine; Cytosine; DNA; Guanine; Insect Viruses; Nucleic Acids; Purines; Pyrimidines; Thymine; Viruses | 1952 |
Studies of nucleic acid metabolism in embryonic tissue culture with the aid of C14-labeled purines.
Topics: Adenine; Guanine; Nucleic Acids; Purines; Tissue Culture Techniques | 1954 |
The estimation of purines in nucleic acids: a method applicable to materials with low concentration of nucleic acid.
Topics: Adenine; Guanine; Nucleic Acids; Purines | 1954 |
The effects of tumor growth, x-radiation, and 8-azaguanine on the incorporation of adenine into nucleic acids of mice.
Topics: Adenine; Animals; Azaguanine; Guanine; Mice; Neoplasms; Nucleic Acids; Sarcoma; X-Rays | 1954 |
Cytological studies on the antimetabolite action of 2, 6-diaminopurine in Vicia faba roots.
Topics: 2-Aminopurine; Adenine; Adenosine; Antimetabolites; Cell Division; Deoxyadenosines; DNA; Growth; Guanine; Hypoxanthine; Purines; Vicia faba | 1955 |
[Substances derived from Crataegus. VIII. Adenosine, adenine, guanine, uric acid].
Topics: Adenine; Adenosine; Crataegus; Guanine; Plant Extracts; Plants; Uric Acid | 1955 |
[Fractionated precipitation of purine bases by silver oxide in a highly acid medium; application to the paper chromatographic determination of adenine, guanine and hypoxanthine in a hydrolysate].
Topics: Adenine; Chromatography; Guanine; Hypoxanthine; Oxides; Purines; Silver Compounds; Xanthines | 1956 |
Participation of bicarbonate in RNA and protein synthesis as indicated by virus propagation in human cells.
Topics: Adenine; Bicarbonates; Cytidine; Cytosine; Deoxyadenosines; DNA; Guanine; Humans; Protein Biosynthesis; Proteins; RNA; Thymidine; Uracil; Uridine; Viruses | 1959 |
[Chronaximtric study of the inhibitory effect of adenine & guanine on various carcinogenic substances].
Topics: Adenine; Carcinogens; Guanine | 1959 |
Similarity of the structure of DNA from a variety of sources.
Topics: Adenine; Animals; Base Composition; Cytosine; DNA; Escherichia coli; Guanine; Humans; Male; Mice; Thymine; X-Ray Diffraction; X-Rays | 1959 |
The incorporation of 8-14C-adenine and 8-14C-guanine into PNA of Rhodospirillum rubrum.
Topics: Adenine; Biochemical Phenomena; Guanine; Metabolic Networks and Pathways; Purines; Rhodospirillum; Rhodospirillum rubrum; RNA | 1961 |
[Paper chromatographic studies on the behavior of adenine-, guanine-, and uridine-nucleotides as well as other acid-soluble phosphorus compounds in the cerebrum of the rat in asphyxia and post-asphyxic recovery].
Topics: Adenine; Animals; Asphyxia; Brain; Cerebrum; Chromatography, Paper; Guanine; Neurochemistry; Nucleosides; Nucleotides; Phosphates; Phosphorus Compounds; Rats; Telencephalon; Uracil Nucleotides; Uridine | 1959 |
Specific action of adenine as a feedback inhibitor of purine biosynthesis.
Topics: Adenine; Biochemical Phenomena; Guanine; Metabolic Networks and Pathways; Purines; Xanthines | 1959 |
Studies on the biosynthesis of riboflavin. 7. The incorporation of adenine and guanine into riboflavin and into nucleic acid purines in Eremothecium ashbyii and Candida flareri.
Topics: Adenine; Candida; Eremothecium; Fungi; Guanine; Nucleic Acids; Purines; Riboflavin | 1962 |
Microbiological assay for thymine using a mutant of Streptococcus faecalis.
Topics: Adenine; Animals; Biological Assay; Enterococcus faecalis; Guanine; Rats; Thymidine; Thymine | 1962 |
The intracellular distribution and heterogeneity of ribonucleic acid in starfish oocytes.
Topics: Adenine; Animals; Cell Nucleolus; Cell Nucleus; Cytoplasm; Cytosine; DNA; Guanine; Oocytes; Ovum; RNA; RNA, Messenger; RNA, Ribosomal; Starfish; Uracil | 1961 |
Transduction in Bacillus subtilis.
Topics: Adenine; Bacillus subtilis; Bacteriophages; Culture Media; Guanine; Histidine; Leucine; Lysogeny; Methionine; Spores, Bacterial | 1962 |
Studies on the analysis of purine and pyrmidine bases of nucleic acid. II. A direct spectrophotometric method for the analysis of the purine and pyramidine bases in ribonucleic acid.
Topics: Adenine; Cytosine; Guanine; Nucleic Acids; Purines; RNA | 1963 |
Base composition of the RNA of a reovirus variant.
Topics: Adenine; Base Composition; Cytosine; Enterovirus B, Human; Guanine; Mammalian orthoreovirus 3; RNA; RNA, Viral; Uracil | 1963 |
Rapidly labelled ribonucleic acid in the cell nucleus.
Topics: Adenine; Cell Nucleus; Dactinomycin; Guanine; RNA | 1963 |
A relationship between compartmentation of purine ribonucleotides and feedback inhibition of denovo purine synthesis.
Topics: Adenine; Guanine; Kinetics; Nucleotides; Purines; Quinolines; Ribonucleotides; Xanthines | 1962 |
Changes in the base composition of nuclear ribonucleic acid of neurons during a short period of enhanced protein production.
Topics: Adenine; Base Composition; Cell Nucleolus; Cell Nucleus; Cytoplasm; Cytosine; Guanine; Neurons; RNA; Uracil | 1962 |
Electrophysiological and neurochemical studies following injection of mononucleotides and their derivatives.
Topics: Adenine; Adenine Nucleotides; Brain; Cytosine; Cytosine Nucleotides; Electroencephalography; Guanine; Guanine Nucleotides; Liver; Nucleosides; Uracil; Uracil Nucleotides | 1963 |
[On the interaction of 2 conjugated systems across a hydrogen bond].
Topics: Adenine; Cytosine; Guanine; Hydrogen; Hydrogen Bonding; Thymine | 1963 |
Relationship between nuclear and cytoplasmic ribonucleic acid.
Topics: Adenine; Cytoplasm; Guanine; RNA | 1963 |
Nucleic acid metabolism in intestinal mucosa. IV. The effect of glucose on incorporation of C-14-formate into purines and pyrimidines in vitro.
Topics: Adenine; Cytosine; DNA; Formates; Glucose; Guanine; In Vitro Techniques; Intestinal Mucosa; Intestine, Small; Intestines; Purines; Pyrimidines; RNA; Uracil | 1963 |
The effect of pyrimidines on the incorporation of purines into riboflavin and RNA by Eremothecium ashbyii.
Topics: Adenine; Ascomycota; Cytosine; Eremothecium; Guanine; Purines; Pyrimidines; Riboflavin; RNA; Uracil | 1962 |
Searches for exploitable biochemical differences between normal and cancer cells. X. Catabolism of purines by regressing tumors.
Topics: Adenine; Breast Neoplasms; Castration; Diethylstilbestrol; Guanine; Humans; Hypophysectomy; Plasmacytoma; Purines; Testosterone; Xanthines | 1962 |
Biosynthesis of S-adenosylmethionine by Saccharomyces cerevisiae. I. Adenine and methionine requirments.
Topics: Adenine; Adenosine; Guanine; Methionine; Naphthalenes; S-Adenosylmethionine; Saccharomyces cerevisiae; Sulfonamides; Yeasts | 1962 |
[Study of DNA in Actinomycetales. Comparison between the values of the A&T/G&C relationship and the bacteriological propof Corynebacterium].
Topics: Actinobacteria; Actinomyces; Actinomycetales; Adenine; Corynebacterium; Cytosine; DNA; DNA, Bacterial; Guanine; Thymine | 1963 |
Incorporation of ribonucleic acid bases into the metabolic pool and RNA of E. coli.
Topics: Adenine; Cytosine; Escherichia coli; Guanine; RNA; RNA, Bacterial | 1963 |
[New microbiological method of determining adenine and guanine for the assay of desoxyribonucleic acid].
Topics: Adenine; DNA; DNA, Bacterial; Guanine | 1962 |
EFFECTS OF COPPER ON BACILLUS SUBTILIS.
Topics: Adenine; Bacillus subtilis; Colorimetry; Copper; Cytosine; DNA; DNA, Bacterial; Guanine; Metabolism; Research; RNA; RNA, Bacterial; Thymine; Tryptophan | 1963 |
STUDIES OF COMPOUNDS THAT INHIBIT CELL GROWTH.
Topics: Acridines; Adenine; Animals; Carcinoma; Carcinoma, Ehrlich Tumor; DNA; DNA, Neoplasm; Guanine; Liver; Mercaptopurine; Mice; Neoplasms; Nucleotides; Pharmacology; Proteins; Research | 1963 |
BASE COMPOSITION OF THE DEOXYRIBONUCLEIC ACID OF SULFATE-REDUCING BACTERIA.
Topics: Adenine; Base Composition; Chromatography; Cytochromes; Cytosine; Desulfovibrio; DNA; DNA, Bacterial; France; Guanine; Research; Spectrophotometry; Sulfates; Thymine | 1963 |
CONFIGURATION AND BASE COMPOSITION OF DEOXYRIBONUCLEIC ACID FROM SPORES OF BACILLUS SUBTILIS VAR. NIGER.
Topics: Adenine; Bacillus subtilis; Base Composition; Centrifugation; Cytosine; DNA; DNA, Bacterial; Formaldehyde; Guanine; Hot Temperature; Muramidase; Niger; Research; Spectrophotometry; Spores, Bacterial; Thymine | 1963 |
PRODUCTION OF LIPASE BY PSEUDOMONAS FRAGI IN A SYNTHETIC MEDIUM.
Topics: Adenine; Amino Acids; Caseins; Culture Media; Fatty Acids; Glucose; Guanine; Lipase; Minerals; Peptones; Pseudomonas; Pseudomonas fragi; United States; Uracil; Vitamins | 1963 |
INTERACTION OF PURINES WITH THE PYRIMIDINE TRANSPORT PROCESS OF THE SMALL INTESTINE.
Topics: Adenine; Caffeine; Carbon Isotopes; Guanine; Intestine, Small; Intestines; Mercaptopurine; Pharmacology; Physiology; Purines; Pyrimidines; Rats; Research; Theobromine; Theophylline; Uracil; Uric Acid; Xanthines | 1963 |
PHOTOSENSITIZED INACTIVATION OF DEOXYRIBONUCLEIC ACID.
Topics: Adenine; Bacillus subtilis; Carbon Isotopes; DNA; DNA, Bacterial; Guanine; Light; Photosensitizing Agents; Research; Riboflavin; Spectrophotometry | 1963 |
A QUANTITATIVE MICRO METHOD FOR DETERMINATION OF SPECIFIC RADIOACTIVITIES OF H3-PURINES AND H3-PYRIMIDINES.
Topics: Adenine; Chemistry Techniques, Analytical; Cytosine Nucleotides; Electrophoresis; Guanine; Microchemistry; Purines; Pyrimidines; Radioactivity; Research; RNA; Tritium; Uracil Nucleotides | 1963 |
AMINOIMIDAZOLECARBOXAMIDE AND FORMATE INCORPORATION INTO WHEAT EMBRYO PURINES.
Topics: Adenine; Amides; Formates; Guanine; Imidazoles; Metabolism; Purines; Research; Triticum | 1963 |
THE EFFECT OF SOME TRANSPLANTABLE TUMORS ON THE NUCLEIC ACID METABOLISM OF THE HOST TISSUES.
Topics: Adenine; Animals; Carbon Isotopes; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; DNA; DNA, Neoplasm; Formates; Guanine; Kidney; Liver; Liver Neoplasms; Lung; Metabolism; Mice; Rats; Research; RNA; RNA, Neoplasm; Spleen; Thymidine; Tritium | 1963 |
BRAIN GUANINE DEAMINASE: PURIFICATION, PROPERTIES AND REGIONAL DISTRIBUTION.
Topics: Adenine; Adenine Nucleotides; Aminohydrolases; Animals; Brain; Cerebral Cortex; Guanine; Guanine Deaminase; Guanine Nucleotides; Haplorhini; Hydrogen-Ion Concentration; Mercaptopurine; Nucleosides; Rats; Research; Sheep; Spectrum Analysis; Thalamus | 1963 |
A BIOCHEMICAL GLIA ERROR IN THE PARKINSON DISEASE.
Topics: Adenine; Cytosine; Globus Pallidus; Guanine; Neurochemistry; Neuroglia; Neurons; Nucleic Acids; Parkinson Disease; Parkinsonian Disorders; RNA; Uracil | 1963 |
THE BASE COMPOSITION OF RIBONUCLEIC ACID IN LAMPBRUSH CHROMOSOMES, NUCLEOLI, NUCLEAR SAP, AND CYTOPLASM OF TRITURUS OOCYTES.
Topics: Adenine; Animals; Base Composition; Cell Nucleolus; Cell Nucleus; Chromatin; Chromosomes; Cytoplasm; Cytosine; DNA; Electrophoresis; Germ Cells; Guanine; Oocytes; Research; RNA; Triturus; Uracil; Urodela | 1963 |
[DETERMINATIONS OF SOME NITROGENOUS BASES IN MEATS].
Topics: Adenine; Animals; Cattle; Creatine; Creatinine; Goats; Guanine; Horses; Meat; Muscles; Nitrogen; Poultry; Purines; Rabbits; Sheep; Sheep, Domestic; Xanthines | 1963 |
REACTION OF THE CARCINOGEN DIMETHYLNITROSAMINE WITH NUCLEIC ACIDS IN VIVO.
Topics: Adenine; Carbon Isotopes; Carcinogens; Dimethylnitrosamine; DNA; Guanine; Kidney; Liver; Metabolism; Nitrosamines; Nucleic Acids; Rats; Research; Ribonucleases; RNA | 1963 |
FRACTIONS WITH DIFFERING BASE COMPOSITION IN RNA FROM MALIGNANT CELLS OF MOUSE.
Topics: Adenine; Animals; Autoradiography; Base Composition; Cytosine; Electrophoresis; Guanine; Mice; Neoplasms; Neoplasms, Experimental; Phosphoric Monoester Hydrolases; Phosphorus Isotopes; Research; RNA; RNA, Neoplasm; Spectrophotometry; Uracil | 1963 |
[SEMI-CONDUCTIBILITY OF DNA (DESOXYRIBONUCLEIC ACID) AND OF PURINE AND PYRIMIDINE BASES OF DNA AND RNA (RIBONUCLEIC ACID)].
Topics: Adenine; Cytosine; DNA; Electrophysiology; Guanine; Purines; Pyrimidines; Research; RNA; Thymine; Uracil | 1963 |
[A FILAMENTOUS DNA PHAGE (FD) AND A SPHERICAL RNA PHAGE (FR), HOST-SPECIFIC FOR THE MALE STRAIN OF E. COLI. 1. PREPARATION AND CHEMICAL PROPERTIES OF FD AND FR].
Topics: Adenine; Coliphages; Culture Media; Cytosine; DNA; DNA, Viral; Escherichia coli; Guanine; Research; RNA; RNA Phages; RNA, Viral; Thymine | 1963 |
STUDIES ON THE ACTIONS OF PYRAZOLOPYRIMIDINES IN MICROORGANISMS. I. 4-HYDROXY-6-AMINOPYRAZOLOPYRIMIDINE.
Topics: Adenine; Antimetabolites; Bacillus cereus; Carbon Isotopes; Culture Media; Escherichia coli; Formates; Guanine; Methionine; Mutation; Pharmacology; Phosphates; Phosphorus Isotopes; Purines; Pyrazoles; Pyrimidines; Research; RNA; RNA, Bacterial | 1964 |
STUDIES ON THE ACTIONS OF PYRAZOLOPYRIMIDINES IN MICROORGANISMS. II. 4-AMINOPYRAZOLOPYRIMIDINE.
Topics: Acetates; Adenine; Antimetabolites; Bacillus cereus; Carbon Isotopes; Escherichia coli; Formates; Glycine; Guanine; Histidine; Leucine; Methionine; Nucleosides; Pharmacology; Phosphates; Phosphorus Isotopes; Pimelic Acids; Proteins; Purines; Pyrazoles; Pyrimidines; Research; Uracil | 1964 |
[THE EFFECT OF SODIUM NITRITE ON NUCLEIC ACID BASES AND ITS RELATION TO THE INACTIVATION OF YEAST CELLS. 1. THE DEAMINATION OF NUCLEIC ACID BASES IN VITRO AND IN VIVO].
Topics: Adenine; Cytosine; Deamination; DNA; Guanine; In Vitro Techniques; Nitrites; Nucleic Acids; RNA; Sodium Nitrite; Yeasts | 1963 |
METABOLISM OF LEUKEMIC CELLS IN CULTURE; AZASERINE INHIBITION OF J-128 (OSGOOD).
Topics: Adenine; Azaserine; Carbon Isotopes; Glycine; Guanine; Hypoxanthines; Imidazoles; Leukemia; Metabolism; Nucleic Acids; Pharmacology; Purines; Tissue Culture Techniques | 1964 |
UTILIZATION AND INTERCONVERSION OF PURINE BASES AND RIBONUCLEOSIDES BY SALMONELLA TYPHIMURIUM.
Topics: Adenine; Adenine Nucleotides; Carbon Isotopes; Chromatography; Culture Media; Guanine; Guanine Nucleotides; Histidine; Mercaptopurine; Metabolism; Nucleosides; Purines; Research; Ribonucleosides; Salmonella typhimurium; Spectrophotometry | 1964 |
A PHAGE INFECTING SAPROSPIRA GRANDIS.
Topics: Adenine; Adenine Nucleotides; Bacteria; Bacterial Proteins; Bacteriophages; Cellulose; Chemistry Techniques, Analytical; Chromatography; Coliphages; Cytosine; Deoxyribonucleases; DNA; DNA, Bacterial; DNA, Viral; Electrons; Guanine; Microscopy; Microscopy, Electron; Research; Ribonucleases; RNA; RNA, Bacterial; RNA, Viral; Thymine; Uracil; Viral Proteins | 1964 |
CHEMICAL PHYSICAL PROPERTIES OF VIRTUALLY PURE FOOT-AND-MOUTH DISEASE VIRUS.
Topics: Adenine; Animals; Cattle; Centrifugation; Cytosine; DNA; DNA, Viral; Electrons; Foot-and-Mouth Disease Virus; Guanine; Guinea Pigs; Kidney; Microscopy; Microscopy, Electron; Research; RNA; RNA, Viral; Spectrophotometry; Tissue Culture Techniques; Uracil; Virus Cultivation | 1964 |
INFLUENCE OF HISTAMINE ON UTERINE METABOLISM: STIMULATION OF INCORPORATION OF RADIOACTIVITY FROM AMINO ACIDS INTO PROTEIN, LIPID AND PURINES.
Topics: Adenine; Amino Acids; Carbon Isotopes; Castration; Estradiol; Female; Glycine; Guanine; Histamine; Humans; Lipids; Lysine; Metabolism; Pharmacology; Physiology; Proteins; Purines; Radioactivity; Rats; Research; Uterus | 1964 |
FOLIC ACID METABOLISM IN ANTIFOLIC-RESISTANT MUTANTS OF STREPTOCOCCUS FAECALIS.
Topics: Adenine; Drug Resistance, Microbial; Enterococcus faecalis; Folic Acid; Guanine; Metabolism; Methotrexate; Mutation; Purines; Research; Serine; Thymine; Xanthines | 1964 |
REPRESSION BY ADENINE OF THE FORMYLTETRAHYDROFOLATE SYNTHETASE IN AN ANTIFOLIC-RESISTANT MUTANT OF STREPTOCOCCUS FAECALIS.
Topics: Adenine; Bacteriological Techniques; Drug Resistance, Microbial; Enterococcus faecalis; Folic Acid; Formate-Tetrahydrofolate Ligase; Guanine; Ligases; Methotrexate; Mutation; Purines; Research; Tetrahydrofolate Dehydrogenase; Thymine | 1964 |
[ON MOBILITY OF PURINES AND PYRIMIDINE BASES AND THEIR DERIVATIVES DURING ELECTROPHORETIC SEPARATION].
Topics: Adenine; Adenine Nucleotides; Cytosine Nucleotides; Electrophoresis; Guanine; Nucleosides; Nucleotides; Purines; Pyrimidines; Research; Thymidine; Thymine; Uracil | 1964 |
CHROMOSOME PUFFS.
Topics: Adenine; Animals; Autoradiography; Cell Division; Chloramphenicol; Chromosomal Puffs; Chromosomes; Dactinomycin; Diptera; DNA; Drosophila; Electrons; Electrophoresis; Guanine; Microscopy; Microscopy, Electron; Mitomycin; Mitomycins; Nucleic Acids; Photomicrography; Research; RNA; Uracil | 1964 |
[CURRENT DATA ON THE BIO-STRUCTURES AND FUNCTIONS OF THE CELL NUCLEUS IN NORMAL AND PATHOLOGICAL CONDITIONS. I. BIO-STRUCTURE OF THE NUCLEUS].
Topics: Adenine; Biochemical Phenomena; Biochemistry; Cell Nucleus; Cytosine; DNA; Guanine; Proteins; RNA; Thymine | 1964 |
URINARY EXCRETION OF SOME PURINE BASES IN NORMAL AND SCHIZOPHRENIC SUBJECTS.
Topics: Adenine; Biomedical Research; Creatine; Creatinine; Guanine; Humans; Hypoxanthines; Purines; Schizophrenia; Urine; Xanthines | 1964 |
STUDIES ON THE INHIBITION OF BACILLUS SUBTILIS GROWTH BY CORDYCEPIN.
Topics: Adenine; Anti-Bacterial Agents; Bacillus subtilis; Culture Media; Deoxyadenosines; Fructose; Guanine; Hypoxanthines; Imidazoles; Mannose; Metabolism; Nucleosides; Pentoses; Pharmacology; Research; Rhamnose; Ribose; Ultraviolet Rays; Xanthines; Xylose | 1964 |
PURINE METABOLISM OF UNICELLULAR ALGAE. I. CHROMATOGRAPHIC DETECTION OF SOME PURINES, PYRIMIDINES, AND IMIDAZOLES BY THEIR MERCURIC COMPLEXES.
Topics: Adenine; Alloxan; Chromatography; Creatine; Creatinine; Eukaryota; Guanine; Hydantoins; Hypoxanthines; Imidazoles; Mercury; Orotic Acid; Purines; Pyrimidines; Research; Ultraviolet Rays; Uric Acid; Xanthines | 1964 |
THE RIBONUCLEIC ACID IN THE MAUTHNER NEURON OF THE GOLDFISH.
Topics: Adenine; Animals; Axons; Cytosine; Fishes; Goldfish; Guanine; Myelin Sheath; Neurochemistry; Neurons; Research; RNA; Uracil | 1964 |
THE EFFECT OF ACTINOMYCIN D ON THE INCORPORATION OF C14-FORMATE INTO NUCLEIC ACIDS OF EHRLICH ASCITES CARCINOMA AND NOVIKOFF HEPATOMA IN VITRO.
Topics: Adenine; Animals; Ascites; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Dactinomycin; DNA; DNA, Neoplasm; Formates; Guanine; In Vitro Techniques; Liver Neoplasms; Liver Neoplasms, Experimental; Pharmacology; Research; RNA; RNA, Neoplasm; Thymine | 1964 |
TRANSFER OF RADIOACTIVITY FROM NUCLEAR TO CYTOPLASMIC RIBONUCLEIC ACID.
Topics: Adenine; Carbon Isotopes; Cell Biology; Cell Nucleus; Cytoplasm; Guanine; Metabolism; Radioactivity; Research; RNA; Tissue Culture Techniques | 1964 |
THE DETERMINATION OF THE BASE COMPOSITION OF DEOXYRIBONUCLEIC ACIDS BY BROMINATION.
Topics: Adenine; Bacillus subtilis; Bacteriophages; Base Composition; Biochemical Phenomena; Biochemistry; Bromides; Cytosine; DNA; DNA, Bacterial; DNA, Viral; Guanine; Haemophilus; Halogenation; Micrococcus; Research; Spectrophotometry; Thymine; Thymus Gland | 1964 |
CHANGES OF THE NUCLEIC ACID CONTENT IN THE RABBIT ORGANS UNDER THE IRRADIATION OF ROENTOGEN RAY.
Topics: Adenine; Adrenal Glands; Antitoxins; Bone Marrow; Cytosine; DNA; Guanine; Liver; Metabolism; Nucleic Acids; Rabbits; Radiation Effects; RNA; Spleen; Thymine; Toxins, Biological; Uracil | 1964 |
STUDIES ON THE ANALYSIS OF PURINE AND PYRIMIDINE BASES OF NUCLEIC ACID. III. A DIRECT SPECTROPHOTOMETRIC METHOD FOR THE ANALYSIS OF THE PURINE AND PYRIMIDINE BASES IN DNA.
Topics: Adenine; Cytosine; DNA; Guanine; Nucleic Acids; Purines; Pyrimidines; Spectrophotometry; Thymine | 1964 |
URACIL: FAILURE TO RESTORE DNA SYNTHESIS WHILE RELIEVING 5-FLUOROURACIL-INDUCED INHIBITION.
Topics: Adenine; Bacillus cereus; Carbon Isotopes; DNA; DNA, Bacterial; Fluorouracil; Formates; Guanine; Hypoxanthines; Metabolism; Pharmacology; Proteins; Research; RNA; Uracil | 1964 |
FORMATION OF RIBOMONONUCLEOTIDES FROM PURINE AND PYRIMIDINE BASES AND 5'-PHOSPHORIBOSYLPYROPHOSPHATE BY A SALMON MILT EXTRACT.
Topics: Adenine; Adenine Nucleotides; Animals; Carbon Isotopes; Chromatography; Cytosine; Cytosine Nucleotides; Diphosphates; Fishes; Guanine; Guanine Nucleotides; Metabolism; Nucleotides; Orotic Acid; Phosphoribosyl Pyrophosphate; Purines; Pyrimidines; Research; Salmon; Thymine; Tissue Extracts; Tritium; Uracil; Uracil Nucleotides; Xanthines | 1964 |
[APROPOS OF THE INJURY TO THE DNA STRUCTURE UNDER THE INFLUENCE OF LARGE DOSES OF GAMMA-RAYS IN VITRO].
Topics: Adenine; Cytosine; DNA; Gamma Rays; Guanine; In Vitro Techniques; Radiation Injuries; Radiation Injuries, Experimental; Radiometry; Research; Thymine; Thymus Gland | 1964 |
QUANTITATIVE E.S.R.-MEASUREMENTS OF RADIATION-INDUCED RADICALS IN NUCLEIC-ACID BASES AND PENTOSES.
Topics: Adenine; Chemistry Techniques, Analytical; Cytosine; Electron Spin Resonance Spectroscopy; Guanine; Inorganic Chemicals; Nucleic Acids; Pentoses; Pyrimidines; Radiation; Radiation Effects; Research; Ribose; Thymine; Uracil; Xanthines | 1964 |
FRACTIONATION OF RIBONUCLEIC ACIDS.
Topics: Adenine; Adsorption; Chemistry Techniques, Analytical; Chromatography; Cytosine; Guanine; Liver; Purines; Pyrimidines; Research; RNA; Saccharomyces; Serratia marcescens; Uracil | 1964 |
NUTRITIONAL MUTATIONS AND TRANSDUCTION BY ULTRAVIOLET-INACTIVATED PHAGE IN STAPHYLOCOCCUS AUREUS.
Topics: Adenine; Genetics; Guanine; Guanosine; Inosine; Italy; Mutation; Nucleosides; Pharmacology; Purines; Staphylococcal Infections; Staphylococcus; Staphylococcus aureus; Staphylococcus Phages; Ultraviolet Rays | 1964 |
DEOXYRIBONUCLEIC ACIDS OF CRUSTACEA.
Topics: Adenine; Animals; Chemistry Techniques, Analytical; Crustacea; Cytosine; DNA; Guanine; Research; Thymine | 1964 |
EFFECTS OF ANTIMITOTIC AGENTS ON EHRLICH ASCITES CELLS.
Topics: Acridines; Adenine; Amino Acids; Animals; Antimetabolites; Antimitotic Agents; Antineoplastic Agents; Ascites; Carbon Isotopes; Carcinoma, Ehrlich Tumor; DNA; DNA, Neoplasm; Glycine; Guanine; Hypoxanthines; Pharmacology; Podophyllum; Purines; Research; RNA; RNA, Neoplasm; Thymidine; Tritium; Xanthines | 1964 |
IDENTIFICATION OF THE ALTERED BASES IN MUTATED SINGLE-STRANDED DNA. II. IN VIVO MUTAGENESIS BY 5-BROMODEOXYURIDINE AND 2-AMINOPURINE.
Topics: 2-Aminopurine; Adenine; Antineoplastic Agents; Bromodeoxyuridine; Coliphages; Cytosine; Cytosine Nucleotides; DNA; DNA, Single-Stranded; DNA, Viral; Guanine; Guanine Nucleotides; Mutagenesis; Mutation; Nucleosides; Purines; Research; Thymidine; Thymine | 1964 |
IDENTIFICATION OF THE ALTERED BASES IN MUTATED SINGLE-STRANDED DNA. 3. MUTAGENESIS BY ULTRAVIOLET LIGHT.
Topics: Adenine; Alkylating Agents; Antineoplastic Agents; Coliphages; Cytosine; DNA; DNA, Single-Stranded; DNA, Viral; Guanine; Hydroxylamines; Mutagenesis; Mutation; Nitrites; Radiation Effects; Research; Thymine; Ultraviolet Rays | 1964 |
HETEROGENEITY OF THE INTERACTION OF DNA WITH ACRIFLAVINE.
Topics: Acridines; Acriflavine; Adenine; Animals; Cattle; Cell Physiological Phenomena; Chemical Phenomena; Chemistry; Chemistry Techniques, Analytical; Cytosine; DNA; DNA, Bacterial; Fluorescence; Guanine; Research; Thymine | 1964 |
THE IONIZATION POTENTIALS OF THE PI- AND LONE-PAIR ELECTRONS OF BIOCHEMICAL PURINES AND PYRIMIDINES.
Topics: Adenine; Chemical Phenomena; Chemistry, Physical; Cytosine; Electrons; Guanine; Purines; Pyrimidines; Research; Uracil | 1964 |
NUTRITION OF "ADENINELESS" AUXOTROPHS OF YEASTS.
Topics: Adenine; Guanine; Guanosine; Hypoxanthine; Hypoxanthines; Inosine; Nucleosides; Nucleotides; Purines; Research; Ribonucleotides; Saccharomyces; Xanthines; Yeasts | 1964 |
SEQUENCE SPECIFICITY IN SYNTHETIC POLYDEOXYRIBONUCLEOTIDES.
Topics: Adenine; Adenine Nucleotides; Biochemical Phenomena; Biochemistry; Chromatography; Cytosine; Guanine; Nucleosides; Nucleotides; Polydeoxyribonucleotides; Research; Thymidine; Thymine | 1964 |
THE INFLUENCE OF HETEROATOMS AND SUBTITUENTS ON THE TAUTOMERIC EQUILIBRIA IN BIOCHEMICAL PURINES AND PYRIMIDINES. I. AZAPURINES AND AZAPYRIMIDINES.
Topics: Adenine; Amines; Cytosine; Guanine; Hypoxanthines; Imines; Kinetics; Nitrogen; Purines; Pyrimidines; Research; Thymine; Uracil; Xanthines | 1964 |
RIBONUCLEIC ACID SYNTHESIS AND TURNOVER IN RAT LIVER AND IN A RAPIDLY GROWING TRANSPLANTABLE HEPATOMA.
Topics: Adenine; Carcinoma, Hepatocellular; Cytosine; Electrophoresis; Guanine; Histocytochemistry; Liver; Liver Neoplasms; Metabolism; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Research; RNA; RNA, Neoplasm; Uracil | 1964 |
RAPIDLY LABELED RIBONUCLEIC ACIDS OF RHODOPSEUDOMONAS SPHEROIDES UNDER VARYING CONDITIONS OF CATALASE SYNTHESIS.
Topics: Adenine; Catalase; Chemistry Techniques, Analytical; Cytosine; DNA; DNA, Bacterial; Guanine; Metabolism; Research; Rhodobacter sphaeroides; Rhodopseudomonas; RNA; RNA, Bacterial; Spectrophotometry; Thymine; Uracil; Uracil Nucleotides | 1964 |
DISTRIBUTION OF NUCLEOSIDE TRIPHOSPHATASES IN HUMAN ERYTHROCYTES.
Topics: Adenine; Chemistry Techniques, Analytical; Erythrocytes; Guanine; Humans; Hydrogen-Ion Concentration; Kinetics; Nucleoside-Triphosphatase; Nucleosides; Nucleotidyltransferases; Research; Uracil | 1964 |
EFFECTS OF ADENINE AND GUANINE ON HEPATIC GLUCOSE RELEASE AND ON THE ACTION OF INSULIN ON THE LIVER.
Topics: Adenine; Carbohydrate Metabolism; Glucose; Guanine; Insulin; Liver; Rats; Research | 1964 |
SOME METABOLIC EFFECTS EXERTED BY AZASERINE AND PURINE ANALOGS IN VIVO.
Topics: Adenine; Amino Acids; Animals; Antimetabolites; Antineoplastic Agents; Azaserine; Carbon Isotopes; Glycine; Guanine; Mercaptopurine; Metabolism; Mice; Neoplasm Transplantation; Nucleotides; Pharmacology; Purines; Research; Sarcoma 180 | 1964 |
THE METABOLISM OF THIOGUANINE IN PURINE ANALOG-RESISTANT CELLS.
Topics: Adenine; Animals; Antimetabolites; Antineoplastic Agents; Cell Biology; DNA; DNA, Neoplasm; Guanine; Metabolism; Mice; Nucleotides; Pharmacology; Purines; Research; RNA; RNA, Neoplasm; Sarcoma 180; Thioguanine | 1964 |
PURIFICATION AND PROPERTIES OF THE TRANSGLUCOSYLASE INHIBITOR OF MYCOBACTERIUM TUBERCULOSIS.
Topics: Adenine; Disaccharides; Edetic Acid; Enzyme Inhibitors; Glucose; Glucosyltransferases; Guanine; Mycobacterium tuberculosis; Nucleosides; Nucleotides; Phosphates; Polynucleotides; Research; RNA; RNA, Bacterial; Transferases; Uracil Nucleotides | 1964 |
RECOMBINATION BETWEEN NOCARDIA ERYTHROPOLIS AND NOCARDIA CANICRURIA.
Topics: Adenine; Alanine; Anti-Bacterial Agents; Arginine; Cysteine; Cystine; Drug Resistance; Drug Resistance, Microbial; Glycine; Guanine; Histidine; Hypoxanthines; Isoleucine; Leucine; Lysine; Metabolism; Methionine; Mutation; Nocardia; Recombination, Genetic; Research; Streptomycin; Valine; Xanthines | 1964 |
[HALOGENATION OF NUCLEIC ACIDS. I. ACTION OF BROMINE ON BASES AND NUCLEOSIDES IN DIMETHYLFORMAMIDE MEDIUM].
Topics: Adenine; Bromine; Chemical Phenomena; Chemistry; Cytosine; Dimethylformamide; Guanine; Halogenation; Nucleic Acids; Nucleosides; Research; Solvents; Ultraviolet Rays; Uracil | 1964 |
[SEPARATION OF DNA COMPONENTS ON CELLULOSE LAYERS].
Topics: Adenine; Cellulose; Chromatography; Cytosine; DNA; Guanine; Nucleosides; Nucleotides; Research; Thymine; Uracil | 1964 |
PURINE AND PYRIMIDINES IN SEDIMENTS FROM THE EXPERIMENTAL MOHOLE.
Topics: Adenine; Chemistry Techniques, Analytical; Cytosine; Guanine; Purines; Pyrimidines; Research; Soil; Thymine; Uracil | 1964 |
[INFLUENCE OF THE HYDROGEN BOND ON THE DIPOLAR MOMENT OF PURINE-PYRIMIDINE PAIRS OF NUCLEIC ACIDS].
Topics: Acetates; Adenine; Amines; Biochemical Phenomena; Biochemistry; Cytosine; Guanine; Hydrogen; Nucleic Acids; Purines; Pyridines; Pyrimidines; Research; Thymine | 1964 |
[ON THE SEMI-CONDUCTIVITY OF PURINE AND PYRIMIDINE BASES OF NUCLEIC ACIDS].
Topics: Adenine; Chemical Phenomena; Chemistry, Physical; Cytosine; Guanine; Nucleic Acids; Purines; Pyrimidines; Research; Thymine; Uracil | 1964 |
SOME PHYSICAL-CHEMICAL AND BIOLOGICAL PROPERTIES OF THE ROD-SHAPED COLIPHAGE M13.
Topics: Adenine; Bacteriophage M13; Coliphages; Cytosine; Deoxyribonucleases; DNA; DNA, Viral; Electrons; Galactosidases; Guanine; Immune Sera; Microscopy; Microscopy, Electron; Peptide Hydrolases; Pharmacology; Rabbits; Research; Thymine; Trypsin; Ultraviolet Rays | 1964 |
METHYLATION OF DEOXYRIBONUCLEIC ACID BY DIAZOMETHANE.
Topics: Adenine; Animals; Azo Compounds; Diazomethane; DNA; Fishes; Guanine; Male; Methylation; Phosphates; Research; RNA; Spectrophotometry; Spermatozoa | 1964 |
RADIATION RESISTANCE AND DEOXYRIBONUCLEIC ACID BASE COMPOSITION OF MICROCOCCUS RADIODURANS.
Topics: Adenine; Base Composition; Cytosine; Deinococcus; DNA; DNA, Bacterial; Guanine; Micrococcus; Mutation; Purines; Pyrimidines; Radiation Genetics; Research; Thymine; Ultraviolet Rays | 1964 |
DEVELOPMENT AND PROPERTIES OF MOUSE LEUKEMIA L1210 RESISTANT TO MIRACIL D.
Topics: Adenine; Animals; Azaguanine; Cyclophosphamide; Enzyme Inhibitors; Folic Acid; Glutamates; Guanine; Leucovorin; Leukemia L1210; Lucanthone; Mercaptopurine; Methotrexate; Mice; Pharmacology; Proadifen; Pyridoxine; Research; Thioguanine | 1964 |
STUDIES ON THE NUCLEOTIDE ARRANGEMENT IN DEOXYRIBONUCLEIC ACIDS. 8. A COMPARISON OF PROCEDURES FOR THE DETERMINATION OF THE FREQUENCY OF PYRIMIDINE NUCLEOTIDE RUNS.
Topics: Adenine; Chemical Phenomena; Chemistry; Cytosine; DNA; Guanine; Nucleotides; Pyrimidine Nucleotides; Research; Spleen; Thymine; Thymus Gland | 1964 |
A RAPID METHOD FOR THE SEPARATION OF NUCLEIC ACID BASES.
Topics: Adenine; Chromatography; Cytosine; Guanine; Nucleic Acids; Purines; Pyrimidines; Research; Spectrum Analysis; Thymine; Uracil | 1964 |
BASE COMPOSITION OF RNA OF THE SUBCELLULAR FRACTIONS FROM GUINEA PIG BRAINS.
Topics: Adenine; Animals; Base Composition; Brain; Brain Chemistry; Cell Nucleus; Cytosine; Guanine; Guinea Pigs; Histocytochemistry; Microsomes; Mitochondria; Myelin Sheath; Research; RNA; Subcellular Fractions; Uracil | 1964 |
ANTAGONISM BETWEEN PURINES IN PURINE-REQUIRING BACILLUS SUBTILIS MUTANTS.
Topics: 2-Aminopurine; Adenine; Adenine Nucleotides; Azaguanine; Bacillus subtilis; Guanine; Guanine Nucleotides; Hypoxanthines; Mercaptopurine; Metabolism; Mutation; Nucleosides; Nucleotides; Pharmacology; Purines; Research; Xanthines | 1964 |
ANTAGONISM BY PURINES AND DERIVATIVES IN THE NUTRITION OF A BACILLUS SUBTILIS MUTANT.
Topics: Adenine; Bacillus subtilis; Guanine; Guanine Nucleotides; Hypoxanthines; Metabolism; Mutation; Nucleosides; Purines; Research; Xanthines | 1964 |
INTERMOLECULAR FORCES IN ASSOCIATION OF PURINES WITH POLYBENZENOID HYDROCARBONS.
Topics: Adenine; Benzopyrenes; Caffeine; Chemical Phenomena; Chemistry; Cytosine; Guanine; Hypoxanthines; London; Purines; Pyrimidines; Research; Thymine; Uracil; Uric Acid; Xanthines | 1965 |
REGULATION OF PURINE RIBONUCLEOTIDE SYNTHESIS BY END PRODUCT INHIBITION. THE EFFECT OF ADENINE AND GUANINE RIBONUCLEOTIDES ON THE 5'-PHOSPHORIBOSYL-PYROPHOSPHATE AMIDOTRANSFERASE OF AEROBACTER AEROGENES.
Topics: Adenine; Adenine Nucleotides; Amidophosphoribosyltransferase; Carbon Isotopes; Diphosphates; Enterobacter aerogenes; Enzyme Inhibitors; Feedback; Glucosyltransferases; Guanine; Guanine Nucleotides; Metabolism; Research; Ribonucleotides | 1965 |
[STUDY OF THE PASSAGE OF CERTAIN PRECURSORS OF NUCLEIC ACIDS FROM THE CEREBROSPINAL FLUID INTO THE CENTRAL NERVOUS SYSTEM].
Topics: Adenine; Blood; Blood-Brain Barrier; Carbon Isotopes; Guanine; Nucleic Acids; Nucleosides; Nucleotides; Orotic Acid; Physiology; Radiometry; Rats; Research; Uracil; Uridine | 1964 |
METABOLISM OF PURINE NUCLEOSIDE ANALOGS.
Topics: Adenine; Animals; Antimetabolites; Guanine; Mercaptopurine; Metabolism; Mice; Neoplasms; Neoplasms, Experimental; Nucleosides; Purine Nucleosides; Purines; Research | 1965 |
SOME ABNORMAL PROPERTIES OF CHLORAMPHENICOL RNA.
Topics: Adenine; Biochemical Phenomena; Biochemistry; Centrifugation; Chloramphenicol; Chromatography; Cytosine; Escherichia coli; Guanine; Research; Ribosomes; RNA; RNA, Bacterial; Uracil | 1964 |
EFFECTS OF THIOACETAMIDE ON NUCLEAR AND NUCLEOLAR RNA OF THE RAT LIVER.
Topics: Adenine; Amides; Anesthetics, Local; Carbon Isotopes; Cell Nucleolus; Cell Nucleus; Cytosine; Guanine; Liver; Metabolism; Orotic Acid; Rats; Research; RNA; Sulfhydryl Compounds; Thioacetamide; Uracil | 1965 |
SPECIFICITY OF DNA FROM NEOPLASTIC TISSUES IN VIVO AND IN VITRO.
Topics: Adenine; Animals; Carbon Isotopes; Cytosine; DNA; DNA, Neoplasm; Formates; Guanine; Histocytochemistry; In Vitro Techniques; Mice; Neoplasms; Neoplasms, Experimental; Research; Thymine | 1964 |
ON THE OXIDATIVE PHOSPHORYLATION AND NUCLEIC ACIDS METABOLISM IN SOME ORGANS OF ANIMALS WITH TRANSPLANTABLE TUMOURS.
Topics: Adenine; Carbohydrate Metabolism; Cytosine; DNA; DNA, Neoplasm; Glycolysis; Guanine; Intestines; Kidney; Liver; Metabolism; Neoplasm Transplantation; Neoplasms; Oxidative Phosphorylation; Phosphorus Isotopes; Pyrimidines; Rats; Research; Sarcoma; Sarcoma, Experimental; Spleen; Thymine | 1964 |
THE EFFECTS OF 3'-DEOXYADENOSINE ON THE SYNTHESIS OF RIBONUCLEIC ACID.
Topics: Adenine; Adenosine Triphosphate; Antimetabolites; Antineoplastic Agents; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cytosine Nucleotides; Deoxyadenosines; Formates; Glycine; Guanine; Metabolism; Mice; Neoplasms; Nucleosides; Nucleotidyltransferases; Orotic Acid; Pharmacology; Polynucleotides; Research; RNA; RNA, Neoplasm; Tissue Culture Techniques; Uracil Nucleotides; Xanthines | 1965 |
ADSORPTION OF DNA COMPONENTS ON THE MERCURY ELECTRODE.
Topics: Adenine; Adsorption; DNA; Electrodes; Guanine; Hypoxanthines; Mercury; Polarography; Research; Xanthines | 1965 |
THIN-LAYER CHROMATOGRAPHY OF NUCLEOTIDES, NUCLEOSIDES AND NUCLEIC ACID BASES.
Topics: Adenine; Carbon Isotopes; Cellulose; Chromatography; Chromatography, Thin Layer; Cytosine; Guanine; Nucleic Acids; Nucleosides; Nucleotides; Research; Uracil | 1965 |
METABOLIC EFFECTS OF AN ANTIBIOTIC, NSC-51954, ON SUSCEPTIBLE AND RESISTANT TUMOR CELLS.
Topics: Adenine; Animals; Anti-Bacterial Agents; Carbon Isotopes; Carcinoma, Ehrlich Tumor; DNA; DNA, Neoplasm; Guanine; Guanine Nucleotides; Leukemia; Leukemia, Experimental; Mice; Neoplasm Proteins; Neoplasms; Orotic Acid; Pharmacology; Phosphotransferases; Proteins; Radiometry; Research; RNA; RNA, Neoplasm; Sarcoma 180; Toxicology; Uracil | 1965 |
THE BASE COMPOSITION OF RNA FROM NUCLEOLI FORMED AT TWO DIFFERENT ORGANIZERS IN CHIRONOMUS TENTANS.
Topics: Adenine; Animals; Base Composition; Biochemical Phenomena; Biochemistry; Cell Nucleolus; Cell Nucleus; Chironomidae; Cytosine; Diptera; Electrophoresis; Guanine; Research; RNA; Salivary Glands; Uracil | 1965 |
BASE COMPOSITION OF RNA SYNTHESIZED DURING CLEAVAGE OF THE SEA URCHIN EMBRYO.
Topics: Adenine; Animals; Base Composition; Biochemical Phenomena; Biochemistry; Centrifugation; Cytosine; Echinodermata; Embryo, Mammalian; Embryo, Nonmammalian; Embryology; Guanine; Metabolism; Ovum; Research; Ribosomes; RNA; Sea Urchins; Uracil | 1965 |
NUCLEOLAR RNA COMPOSITION DURING GROWTH OF THE STARFISH OOCYTE.
Topics: Adenine; Animals; Biochemical Phenomena; Biochemistry; Cell Nucleolus; Cell Nucleus; Cytoplasm; Cytosine; Echinodermata; Electrophoresis; Guanine; Oocytes; Ovum; Research; RNA; Starfish; Uracil | 1965 |
AVAILABILITY OF 5-PHOSPHORIBOSYL 1-PYROPHOSPHATE FOR RIBONUCLEOTIDE SYNTHESIS IN EHRLICH ASCITES TUMOR CELLS IN VITRO.
Topics: Adenine; Animals; Carcinoma; Carcinoma, Ehrlich Tumor; Dinitrophenols; Diphosphates; Guanine; In Vitro Techniques; Iodoacetates; Metabolism; Methylene Blue; Nucleotides; Pharmacology; Phosphoribosyl Pyrophosphate; Research; Xanthines | 1965 |
THE ENZYMATIC SYNTHESIS OF RIBONUCLEIC ACID IN ANIMAL TISSUE. I. THE DEOXYRIBONUCLEIC ACID-DIRECTED SYNTHESIS OF RIBONUCLEIC ACID AS CATALYZED BY AN ENZYME OBTAINED FROM BOVINE LYMPHOSARCOMA TISSUE.
Topics: Adenine; Animals; Catalysis; Cattle; Cytosine; DNA; DNA Replication; DNA, Bacterial; Enzootic Bovine Leukosis; Guanine; Hot Temperature; Lymphoma, Non-Hodgkin; Metabolism; Micrococcus; Nucleotidyltransferases; Research; RNA; Sarcoma; Sarcoma, Experimental; Thymus Gland; Uracil; Uracil Nucleotides | 1965 |
EFFECT OF AZASERINE ON THE INCORPORATION OF 14-C-LABELED PURINES AND PYRIMIDINES INTO ACID-SOLUBLE AND NUCLEIC ACID FRACTIONS OF TRYPANOSOMA EQUIPERDUM.
Topics: Adenine; Amino Acids; Azaserine; Cytosine; Cytosine Nucleotides; DNA; Glutamine; Guanine; Hypoxanthines; Leucine; Metabolism; Nucleic Acids; Orotic Acid; Pharmacology; Purines; Pyrimidines; Research; RNA; Thymine; Trypanosoma; Tryptophan; Tyrosine; Uracil; Uracil Nucleotides | 1965 |
GROWTH FACTOR REQUIREMENTS OF TWO STRAINS OF SPHAEROTILUS DISCOPHORUS.
Topics: 4-Aminobenzoic Acid; Adenine; Aminobenzoates; Caseins; Culture Media; Guanine; Intercellular Signaling Peptides and Proteins; Metabolism; Methionine; Research; Sphaerotilus; Uracil; Vitamin B Complex | 1965 |
THE STUDY OF PURINE UTILIZATION AND EXCRETION IN A XANTHINURIC MAN.
Topics: Adenine; Carbon Isotopes; Chromatography; Guanine; Humans; Hypoxanthines; Male; Metabolism, Inborn Errors; Nucleotides; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Spectrophotometry; Uric Acid; Urine; Xanthine Oxidase; Xanthines | 1965 |
CELLULAR PHYSIOLOGY DURING LOGARITHMIC GROWTH OF A STREPTOCOCCAL L-FORM.
Topics: Adenine; Chemical Phenomena; Chemistry; Cytosine; DNA; DNA, Bacterial; Guanine; L Forms; Metabolism; Research; RNA; RNA, Bacterial; Streptococcus; Thymine | 1965 |
BASE ANALOGUE INDUCED ARABINOSE-NEGATIVE MUTANTS OF ESCHERICHIA COLI.
Topics: Adenine; Arabinose; Bromodeoxyuridine; Cytosine; DNA; DNA, Bacterial; Escherichia coli; Guanine; Hydroxylamines; Mutation; Purines; Research; Thymine; Uracil Nucleotides | 1965 |
SYNTHETIC MECHANISMS IN THE AXON. II. RNA IN MYELIN-FREE AXONS OF THE CAT.
Topics: Accessory Nerve; Adenine; Axons; Cats; Guanine; Hydroxylamines; Metabolism; Microscopy; Microscopy, Phase-Contrast; Myelin Sheath; Neurochemistry; Research; RNA | 1965 |
DETERMINATION OF BASE RATIOS OF SIX RIBONUCLEIC ACID BACTERIOPHAGES SPECIFIC TO ESCHERICHIA COLI.
Topics: Adenine; Bacteriophages; Base Composition; Biochemical Phenomena; Biochemistry; Chromatography; Coliphages; Cytosine; Deoxyribonucleases; DNA; Electrophoresis; Escherichia coli; Guanine; Hydrolysis; Ion Exchange Resins; Nucleotides; Research; Ribonucleases; Ribosomes; RNA; RNA, Viral; Uracil | 1965 |
STUDIES ON PLACENTAL METABOLISM. II. PURINE NUCLEOTIDE CATABOLISM IN EARLY PLACENTA.
Topics: Adenine; Adenine Nucleotides; Female; Guanine; Guanine Nucleotides; Humans; Hypoxanthines; Metabolism; Nucleotidases; Nucleotides; Placenta; Pregnancy; Purines; Uracil Nucleotides; Xanthines | 1965 |
BIOSYNTHESIS OF RIBOFLAVINE BY A PURINE-REQUIRING MUTANT STRAIN OF ESCHERICHIA COLI.
Topics: Adenine; Escherichia coli; Glycine; Guanine; Imidazoles; Metabolism; Mutation; Nucleic Acids; Purines; Research; Riboflavin | 1965 |
INHIBITION OF PRUINE PHOSPHORIBOSYLTRANSFERASES OF EHRLICH ASCITES-TUMOUR CELLS BY 6-MERCAPTOPURINE.
Topics: Adenine; Adenine Nucleotides; Adenosine Monophosphate; Animals; Ascites; Carcinoma, Ehrlich Tumor; Diphosphates; Electrophoresis; Enzyme Inhibitors; Glucosyltransferases; Guanine; Guanine Nucleotides; Hypoxanthines; Kinetics; Mercaptopurine; Nucleotides; Pharmacology; Purines; Research; Spectrophotometry; Transferases; Xanthines | 1965 |
INHIBITION BY 6-MERCAPTOPURINE OF PURINE PHOSPHORIBOSYLTRANSFERASES FROM EHRLICH ASCITES-TUMOUR CELLS THAT ARE RESISTANT TO THE DRUG.
Topics: Adenine; Adenine Nucleotides; Animals; Ascites; Carcinoma, Ehrlich Tumor; Chromatography; Electrophoresis; Enzyme Inhibitors; Glucosyltransferases; Guanine; Guanine Nucleotides; Humans; Hypoxanthines; Ion Exchange Resins; Kinetics; Mercaptopurine; Metabolism; Nucleotides; Pentosyltransferases; Pharmacology; Research; Xanthines | 1965 |
BASE COMPOSITION OF HIGH MOLECULAR WEIGHT NUCLEAR RNA OF WALKER TUMOR AND LIVER OF THE RAT.
Topics: Adenine; Adenine Nucleotides; Animals; Base Composition; Carcinoma 256, Walker; Cytosine; Cytosine Nucleotides; Guanine; Guanine Nucleotides; Liver; Molecular Weight; Neoplasms; Phosphates; Phosphorus Isotopes; Rats; Research; RNA; RNA, Neoplasm; RNA, Nuclear; Spectrum Analysis; Uracil; Uracil Nucleotides | 1965 |
REGULATION OF XANTHINE DEHYDROGENASE IN CHICK LIVER. EFFECT OF STARVATION AND OF ADMINISTRATION OF PURINES AND PURINE NUCLEOSIDES.
Topics: Adenine; Adenosine; Animals; Chickens; Cortisone; Guanine; Guanosine; Hypoxanthines; Inosine; Liver; Nucleosides; Pharmacology; Poultry; Purine Nucleosides; Purines; Puromycin; Research; Ribonucleosides; Spectrophotometry; Starvation; Xanthine Dehydrogenase; Xanthine Oxidase; Xanthines | 1965 |
Biosynthesis of nucleic acid purines. I. Formation of guanine from adenine compounds in bone marrow extracts.
Topics: Adenine; Adenosine; Biochemical Phenomena; Bone Marrow; Guanine; Nucleic Acids; Purines; Tissue Extracts | 1955 |
Bases of the nucleic acid of fowlpox virus and host deoxyribonucleic acid.
Topics: Adenine; DNA; Fowlpox virus; Guanine; Nucleic Acids; Purines; Pyrimidines; Viruses | 1962 |
CAG repeat length in the androgen receptor gene affects the risk of male infertility.
Topics: Adenine; Adult; Case-Control Studies; Cytosine; Guanine; Humans; Infertility, Male; Male; Multicenter Studies as Topic; Oligospermia; Receptors, Androgen; Retrospective Studies; Risk Factors; Sperm Count; Trinucleotide Repeats | 2003 |
Cytogenetic and molecular analysis of the Y chromosome: absence of a significant relationship between CAG repeat length in exon 1 of the androgen receptor gene and infertility in Indian men.
Topics: Adenine; Adult; Chromosomes, Human, Y; Cytosine; Exons; Follicle Stimulating Hormone; Genotype; Guanine; Humans; India; Infertility, Male; Luteinizing Hormone; Male; Oligospermia; Phenotype; Polymerase Chain Reaction; Receptors, Androgen; Sequence Analysis, DNA; Sequence Tagged Sites; Sex Chromosome Aberrations; Testosterone; Trinucleotide Repeats | 2003 |
New parameterization of the Cornell et al. empirical force field covering amino group nonplanarity in nucleic acid bases.
Topics: Adenine; Base Pairing; Binding Sites; Chemical Phenomena; Chemistry, Physical; Cytosine; Guanine; Hydrogen Bonding; Models, Theoretical; Nucleic Acids; Quantum Theory | 2003 |
DNA sequence recognition by bispyrazinonaphthalimides antitumor agents.
Topics: Adenine; Amides; Animals; Antineoplastic Agents; Base Pairing; Base Sequence; Binding Sites; Cattle; Cytosine; Deoxyribonuclease I; Dimerization; DNA; Guanine; Intercalating Agents; Isoquinolines; Mesylates; Molecular Sequence Data; Nucleic Acid Conformation; Surface Plasmon Resonance; Thymine | 2003 |
GA and AG sequences of DNA react with cisplatin at comparable rates.
Topics: Adenine; Animals; Antineoplastic Agents; Base Sequence; Chelating Agents; Cisplatin; Cross-Linking Reagents; Crotalid Venoms; DNA; DNA Adducts; Exonucleases; Guanine; Kinetics; Nucleic Acid Conformation; Oligonucleotides; Platinum; Sequence Analysis, DNA; Water | 2003 |
On the aromatic character of the heterocyclic bases of DNA and RNA.
Topics: Adenine; Base Pairing; Cytosine; DNA; Guanine; Hydrogen Bonding; Mathematical Computing; Nucleic Acid Conformation; Quantum Theory; RNA; Stereoisomerism; Thymine; Uracil | 2003 |
Isolation of a Chinese hamster cell mutant with low intracellular phosphoribosylpyrophosphate concentration.
Topics: Adenine; Adenine Phosphoribosyltransferase; Animals; Cell Line; Cricetinae; Cricetulus; Guanine; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Mutation; Phosphoribosyl Pyrophosphate; Ribose-Phosphate Pyrophosphokinase; Tritium | 1982 |
The G-217A variant of the angiotensinogen gene affects basal transcription and is associated with hypertension in a Taiwanese population.
Topics: Adenine; Angiotensinogen; Asian People; Genetic Variation; Guanine; Humans; Hypertension; Taiwan; Transcription, Genetic | 2003 |
Two novel aquaporin-2 mutations in a sporadic Japanese patient with autosomal recessive nephrogenic diabetes insipidus.
Topics: Adenine; Aquaporin 2; Aquaporins; Asian People; Base Sequence; Diabetes Insipidus, Nephrogenic; Frameshift Mutation; Genes, Recessive; Guanine; Humans; Infant; Male; Mutation; Pedigree | 2003 |
Strand-specific processing of 8-oxoguanine by the human mismatch repair pathway: inefficient removal of 8-oxoguanine paired with adenine or cytosine.
Topics: Adenine; Base Pair Mismatch; Base Sequence; Cell Line, Tumor; Cytosine; DNA Damage; DNA Repair; Guanine; HeLa Cells; Humans; Models, Genetic | 2003 |
IFN-gamma polymorphisms (IFN-gamma +2109 and IFN-gamma +3810) are associated with severe hepatic fibrosis in human hepatic schistosomiasis (Schistosoma mansoni).
Topics: Adenine; DNA; Genetic Predisposition to Disease; Genotype; Guanine; Humans; Interferon-gamma; Liver Cirrhosis; Liver Diseases, Parasitic; Mutation; Nuclear Proteins; Pedigree; Polymorphism, Single Nucleotide; Schistosomiasis mansoni; Severity of Illness Index; Ultrasonography | 2003 |
Theoretical study of cisplatin binding to purine bases: why does cisplatin prefer guanine over adenine?
Topics: Adenine; Cisplatin; Guanine; Kinetics; Models, Molecular; Substrate Specificity; Thermodynamics | 2003 |
First principles calculations of the pKa values and tautomers of isoguanine and xanthine.
Topics: Adenine; Base Pairing; Deamination; DNA Replication; DNA-Directed DNA Polymerase; Guanine; Hydrogen Bonding; Isoelectric Point; Isomerism; Kinetics; Korea; Mathematics; Oxidation-Reduction; Quantum Theory; Solutions; Xanthine | 2003 |
Association of p53 codon Arg72Pro and p73 G4C14-to-A4T14 at exon 2 genetic polymorphisms with the risk of Japanese breast cancer.
Topics: Adenine; Adult; Aged; Arginine; Breast Neoplasms; Carcinoma, Ductal; Case-Control Studies; Codon; Cytosine; DNA Primers; DNA-Binding Proteins; Exons; Female; Genes, Tumor Suppressor; Genotype; Guanine; Homozygote; Humans; Logistic Models; Middle Aged; Nuclear Proteins; Odds Ratio; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Proline; Thymine; Tumor Protein p73; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2003 |
DNA damage and cytotoxicity induced by minor groove binding methyl sulfonate esters.
Topics: Adenine; Anti-Bacterial Agents; Base Sequence; DNA Adducts; DNA Damage; DNA Fragmentation; DNA Methylation; DNA Repair; DNA, Bacterial; Escherichia coli; Esters; Guanine; Mesylates; Molecular Sequence Data; Netropsin; Nucleic Acid Conformation; Protein Binding | 2003 |
Association of the cyclin D1 A870G polymorphism with advanced colorectal cancer.
Topics: Adenine; Aged; Asian People; Case-Control Studies; Colorectal Neoplasms; Female; Gene Dosage; Genes, bcl-1; Genotype; Guanine; Hawaii; Humans; Logistic Models; Male; Middle Aged; Neoplasm Staging; Polymorphism, Genetic; Risk Factors; White People | 2003 |
True stabilization energies for the optimal planar hydrogen-bonded and stacked structures of guanine...cytosine, adenine...thymine, and their 9- and 1-methyl derivatives: complete basis set calculations at the MP2 and CCSD(T) levels and comparison with ex
Topics: Adenine; Base Pairing; Cytosine; Guanine; Hydrogen Bonding; Models, Chemical; Models, Molecular; Thermodynamics; Thymine | 2003 |
The -3826 A-->G variant of the uncoupling protein-1 gene diminishes postprandial thermogenesis after a high fat meal in healthy boys.
Topics: Adenine; Carrier Proteins; Dietary Carbohydrates; Dietary Fats; Dose-Response Relationship, Drug; Energy Metabolism; Genetic Variation; Genotype; Guanine; Humans; Ion Channels; Male; Membrane Proteins; Mitochondrial Proteins; Polymorphism, Genetic; Postprandial Period; Reference Values; Sympathetic Nervous System; Thermogenesis; Time Factors; Uncoupling Protein 1 | 2003 |
Dissecting the broad substrate specificity of human 3-methyladenine-DNA glycosylase.
Topics: Adenine; Base Pairing; Catalysis; DNA; DNA Glycosylases; Guanine; Humans; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Models, Chemical; Oligonucleotides; Oxygen; Protein Binding; Protein Conformation; Substrate Specificity; Thermodynamics | 2004 |
An adenine-to-guanine nucleotide change in the IRES SL-IV domain of picornavirus/hepatitis C chimeric viruses leads to a nonviable phenotype.
Topics: Adenine; Animals; Base Sequence; Cattle; Gene Expression Regulation, Viral; Guanine; HeLa Cells; Hepacivirus; Humans; Molecular Sequence Data; Mutation; Nucleic Acid Conformation; Picornaviridae; Poliovirus; Protein Biosynthesis; Recombination, Genetic; Ribosomes; RNA, Viral; Transcription, Genetic; Transfection; Viral Plaque Assay | 2003 |
Fluorescence detection of guanine-adenine transition by a hydrogen bond forming small compound.
Topics: Adenine; Base Sequence; Binding Sites; Guanine; Hydrogen Bonding; Nucleic Acid Denaturation; Nucleic Acid Heteroduplexes; Oligodeoxyribonucleotides; Pteridines; Spectrometry, Fluorescence; Temperature | 2003 |
Structural and biochemical analyses of hemimethylated DNA binding by the SeqA protein.
Topics: Adenine; Amino Acid Sequence; Bacterial Outer Membrane Proteins; Base Pair Mismatch; Base Pairing; Base Sequence; Crystallization; Crystallography, X-Ray; DNA; DNA Methylation; DNA-Binding Proteins; Escherichia coli Proteins; Guanine; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Phosphates; Protein Binding; Protein Structure, Tertiary; Response Elements; Salts; Static Electricity; Transcription Factors | 2004 |
Synthesis of base substituted 2-hydroxy-3-(purin-9-yl)-propanoic acids and 4-(purin-9-yl)-3-butenoic acids.
Topics: 2-Aminopurine; Adenine; Antineoplastic Agents; Antiviral Agents; Butyrates; Guanine; Hypoxanthines; Lactic Acid; Magnetic Resonance Spectroscopy; Molecular Structure; Purines | 2003 |
Detection of guanine-adenine mismatches by surface plasmon resonance sensor carrying naphthyridine-azaquinolone hybrid on the surface.
Topics: Adenine; Base Pair Mismatch; Base Sequence; Circular Dichroism; DNA; Guanine; Hydrogen Bonding; Naphthyridines; Nucleic Acid Denaturation; Quinolones; Surface Plasmon Resonance; Temperature; Thermodynamics; Ultraviolet Rays | 2004 |
Ab initio interaction energies of hydrogen-bonded amino acid side chain[bond]nucleic acid base interactions.
Topics: Adenine; Amino Acids; Cytosine; Guanine; Hydrogen Bonding; Thermodynamics; Uracil | 2004 |
Identification and characterization of two forms of mouse MUTYH proteins encoded by alternatively spliced transcripts.
Topics: Adenine; Alternative Splicing; Amino Acid Sequence; Animals; Cell Line; Cell Nucleus; DNA Glycosylases; DNA-(Apurinic or Apyrimidinic Site) Lyase; Gene Deletion; Guanine; Isoenzymes; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Molecular Sequence Data; Protein Transport; Recombinant Fusion Proteins; RNA, Messenger; Solubility; Stem Cells; Thymus Gland | 2004 |
Environmental fluctuations facilitate electron-hole transfer from guanine to adenine in DNA pi stacks.
Topics: Adenine; Base Pairing; DNA; Electron Transport; Energy Transfer; Guanine; Nucleic Acid Conformation; Thermodynamics | 2004 |
CTLA-4 AT-repeat polymorphism reduces the inhibitory function of CTLA-4 in Graves' disease.
Topics: Adenine; Adult; Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation; B-Lymphocytes; Case-Control Studies; Cell Division; Cell Transformation, Viral; CTLA-4 Antigen; Graves Disease; Guanine; Herpesvirus 4, Human; Humans; Monocytes; Polymorphism, Genetic; Repetitive Sequences, Nucleic Acid; T-Lymphocytes; Thymine | 2003 |
Towards preimplantation diagnosis of cystic fibrosis using microarrays.
Topics: Adenine; Alleles; Carbocyanines; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Cytosine; Female; Fluorescent Dyes; Gene Deletion; Guanine; Heterozygote; Homozygote; Humans; Nucleic Acid Hybridization; Oligonucleotide Array Sequence Analysis; Point Mutation; Polymerase Chain Reaction; Pregnancy; Preimplantation Diagnosis | 2004 |
Chemical composition of some components of the arrestment pheromone of the black-legged tick, Ixodes scapularis (Acari: Ixodidae) and their use in tick control.
Topics: Adenine; Animals; Biological Assay; Guanine; Ixodes; Pest Control, Biological; Pheromones; Skin; Xanthine | 2003 |
Overexpression and rapid purification of Escherichia coli formamidopyrimidine-DNA glycosylase.
Topics: Adenine; Carboxymethylcellulose Sodium; Chromatography, DEAE-Cellulose; Cloning, Molecular; DNA Damage; DNA Repair; DNA-Formamidopyrimidine Glycosylase; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Gas Chromatography-Mass Spectrometry; Gene Expression Regulation, Bacterial; Genetic Vectors; Guanine; Kinetics; Nitrous Oxide; Pyrimidines; Recombinant Proteins; Substrate Specificity; Temperature | 2004 |
Association analysis of the -308G>A promoter polymorphism of the tumor necrosis factor alpha (TNF-alpha) gene in Japanese patients with schizophrenia.
Topics: Adenine; Adult; Chi-Square Distribution; Female; Gene Frequency; Guanine; Humans; Japan; Male; Middle Aged; Odds Ratio; Polymorphism, Genetic; Promoter Regions, Genetic; Schizophrenia; Tumor Necrosis Factor-alpha | 2004 |
Novel poly(ADP-ribose) polymerase-1 inhibitor, AG14361, restores sensitivity to temozolomide in mismatch repair-deficient cells.
Topics: Adenine; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Azulenes; Base Pair Mismatch; Benzodiazepines; Cell Division; Cell Line, Tumor; Cisplatin; Dacarbazine; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Genotype; Guanine; Humans; Models, Chemical; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Temozolomide | 2004 |
Factors related to the growth of psittacosis virus (strain 6BC) II. Purines, pyrimidines, and other components related to nucleic acid.
Topics: 2-Aminopurine; Adenine; Benzimidazoles; Guanine; Nucleic Acids; Psittacosis; Pterins; Purines; Pyrimidines | 1952 |
Molecular biology: ensuring error-free DNA repair.
Topics: Adenine; Binding Sites; Crystallography, X-Ray; DNA; DNA Damage; DNA Glycosylases; Geobacillus stearothermophilus; Guanine; N-Glycosyl Hydrolases; Protein Conformation; Structure-Activity Relationship | 2004 |
Structural basis for removal of adenine mispaired with 8-oxoguanine by MutY adenine DNA glycosylase.
Topics: Adenine; Base Pairing; Binding Sites; Catalysis; Cross-Linking Reagents; Crystallography, X-Ray; Disulfides; DNA; DNA Glycosylases; Geobacillus stearothermophilus; Guanine; Models, Molecular; N-Glycosyl Hydrolases; Protein Conformation; Structure-Activity Relationship | 2004 |
Blood acylcarnitine levels in normal newborns and heterozygotes for medium-chain acyl-CoA dehydrogenase deficiency: a relationship between genotype and biochemical phenotype?
Topics: Acyl-CoA Dehydrogenase; Adenine; Carnitine; Diagnosis, Differential; Gene Frequency; Genotype; Guanine; Heterozygote; Humans; Infant, Low Birth Weight; Infant, Newborn; Metabolism, Inborn Errors; Osmolar Concentration; Phenotype | 2004 |
[Myopathy-lipomatosis associated with A8344G mitochondrial DNA mutation].
Topics: Adenine; DNA, Mitochondrial; Female; Guanine; Humans; Lipomatosis; Lysine; Male; Middle Aged; Muscular Diseases; Mutation; RNA, Transfer | 2003 |
TDDFT investigation on nucleic acid bases: comparison with experiments and standard approach.
Topics: Adenine; Cytosine; Guanine; Models, Molecular; Nucleic Acids; Thermodynamics; Thymine; Uracil | 2004 |
A haplotype constituted of four MMP-2 promoter polymorphisms (-1575G/A, -1306C/T, -790T/G and -735C/T) is associated with coronary triple-vessel disease.
Topics: Adenine; Adult; Aged; Aged, 80 and over; Alleles; Case-Control Studies; Coronary Disease; Cytosine; Female; Gene Frequency; Genetic Variation; Genotype; Guanine; Haplotypes; Humans; Male; Matrix Metalloproteinase 2; Middle Aged; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Thymine | 2004 |
Prevalence of the Y165C, G382D and 1395delGGA germline mutations of the MYH gene in Italian patients with adenomatous polyposis coli and colorectal adenomas.
Topics: Adenine; Adenoma; Adenomatous Polyposis Coli; Adult; Aged; Aspartic Acid; Case-Control Studies; Colorectal Neoplasms; Cysteine; DNA Glycosylases; DNA Mutational Analysis; DNA, Neoplasm; Female; Gene Deletion; Gene Frequency; Germ-Line Mutation; Glycine; Guanine; Humans; Italy; Male; Middle Aged; Tyrosine | 2004 |
Using pyrrolo-deoxycytosine to probe RNA/DNA hybrids containing the human immunodeficiency virus type-1 3' polypurine tract.
Topics: Adenine; Base Pairing; Base Sequence; Cytosine; DNA, Viral; Fluorescent Dyes; Guanine; HIV Reverse Transcriptase; HIV-1; Hydrogen Bonding; Mutation; Nucleic Acid Heteroduplexes; Nucleic Acid Probes; Purines; Ribonuclease H; RNA, Viral; Templates, Genetic | 2004 |
Endovascular thrombolytic treatment of extensive dural sinus thrombosis in a heterozygous carrier of prothrombin gene G20210A mutation.
Topics: Adenine; Adult; Endothelium, Vascular; Female; Fibrinolytic Agents; Genetic Carrier Screening; Guanine; Humans; Mutation; Prothrombin; Sinus Thrombosis, Intracranial | 2004 |
Early failure of dental implants and TNF-alpha (G-308A) gene polymorphism.
Topics: Adenine; Adult; Alleles; Chi-Square Distribution; Dental Restoration Failure; DNA; Female; Genotype; Guanine; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Risk Factors; Tumor Necrosis Factor-alpha | 2004 |
Study of Ni(II) ion-DNA interactions with methylene blue as fluorescent probe.
Topics: Adenine; Animals; DNA; Fishes; Fluorescent Dyes; Guanine; Methylene Blue; Molecular Structure; Nickel; Nitrogen; Photobleaching; Spectrometry, Fluorescence | 2004 |
Cellular repair of oxidatively induced DNA base lesions is defective in prostate cancer cell lines, PC-3 and DU-145.
Topics: Adenine; Antioxidants; Blotting, Western; Catalase; Cell Division; Cell Line, Tumor; Cell Nucleus; Comet Assay; Cytosine; DNA; DNA Damage; Dose-Response Relationship, Drug; Electron Transport Complex IV; Gas Chromatography-Mass Spectrometry; Glutathione Peroxidase; Guanine; Humans; Kinetics; Male; Mitochondria; Oxygen; Polymorphism, Genetic; Prostatic Neoplasms; Superoxide Dismutase; Time Factors | 2004 |
Exciplex formation between pyrene and guanine in highly polar solvents.
Topics: Acetonitriles; Adenine; Cytosine; Dimethylformamide; Guanine; Hydrocarbons; Methane; Pyrenes; Solvents; Spectrometry, Fluorescence; Thymine; Uracil; Water | 2004 |
Interactions of HLA-DRB4 and CTLA-4 genes influence thyroid function in Hashimoto's thyroiditis in Japanese population.
Topics: Adenine; Antigens, CD; Antigens, Differentiation; Asian People; Case-Control Studies; CTLA-4 Antigen; Exons; Female; Guanine; HLA-DR Antigens; HLA-DRB1 Chains; HLA-DRB4 Chains; Humans; Polymorphism, Genetic; Thyroid Gland; Thyroiditis, Autoimmune; Thyrotropin | 2003 |
Association of CTLA-4 gene polymorphism with oral submucous fibrosis in Taiwan.
Topics: Adenine; Alleles; Antigens, CD; Antigens, Differentiation; Chi-Square Distribution; CTLA-4 Antigen; Exons; Gene Frequency; Genetic Predisposition to Disease; Genotype; Guanine; Humans; Immunoglobulin Fc Fragments; Lymphocyte Activation; Male; Oral Submucous Fibrosis; Phenotype; Polymorphism, Genetic; T-Lymphocytes; Taiwan | 2004 |
Preparation and antiviral properties of new acyclic, achiral nucleoside analogues: 1- or 9-[3-hydroxy-2-(hydroxymethyl)prop-1-enyl]nucleobases and 1- or 9-[2,3-dihydroxy-2-(hydroxymethyl)propyl]nucleobases.
Topics: Adenine; Animals; Antiviral Agents; Cells, Cultured; Cytosine; Guanine; HIV-1; Molecular Structure; Nucleosides | 2004 |
A theoretical study of structures and electron affinities of radical anions of guanine-cytosine, adenine-thymine, and hypoxanthine-cytosine base pairs.
Topics: Adenine; Algorithms; Base Pairing; Cytosine; DNA; Guanine; Hydrogen Bonding; Models, Theoretical; Nucleic Acid Conformation; Static Electricity; Thymine | 2004 |
A novel missense mutation of the ATP2A2 gene in a Chinese family with Darier's disease.
Topics: Adenine; Adult; Asian People; Base Sequence; Calcium-Transporting ATPases; Darier Disease; Female; Guanine; Heterozygote; Humans; Mutation, Missense; Pedigree; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Skin | 2004 |
A novel mutation in the second half of the keratin 17 1A domain in a large pedigree with delayed-onset pachyonychia congenita type 2.
Topics: Adenine; Age of Onset; Amino Acid Substitution; Asparagine; Aspartic Acid; Base Sequence; Codon; Female; Guanine; Heterozygote; Humans; Keratins; Male; Middle Aged; Mutation; Nail Diseases; Pedigree; Protein Structure, Tertiary | 2004 |
Collisionally-induced dissociation of purine antiviral agents: mechanisms of ion formation using gas phase hydrogen/deuterium exchange and electrospray ionization tandem mass spectrometry.
Topics: Acyclovir; Adenine; Antiviral Agents; Deuterium Exchange Measurement; Gases; Guanine; Hydrogen; Ions; Molecular Structure; Protons; Purines; Spectrometry, Mass, Electrospray Ionization; Vidarabine; Vidarabine Phosphate | 2004 |
Efficient synthesis of an adenosine A2a agonist: glycosylation of 2-haloadenines and an N2-alkyl-6-chloroguanine.
Topics: Adenine; Adenosine; Adenosine A2 Receptor Agonists; Alkylation; Anti-Inflammatory Agents; Glycosylation; Guanine; Hydrocarbons, Halogenated; Maleates; Molecular Structure; Purines; Ribose | 2004 |
Androgen receptor gene cytosine, adenine, and guanine trinucleotide repeats in patients with endometriosis.
Topics: Adenine; Adult; Alleles; Cytosine; Endometriosis; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Guanine; Humans; Polymerase Chain Reaction; Receptors, Androgen; Repetitive Sequences, Nucleic Acid | 2004 |
NMR structure of the DNA decamer duplex containing double T*G mismatches of cis-syn cyclobutane pyrimidine dimer: implications for DNA damage recognition by the XPC-hHR23B complex.
Topics: Adenine; Base Pair Mismatch; DNA Damage; DNA Repair Enzymes; DNA-Binding Proteins; Guanine; Macromolecular Substances; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Nucleic Acid Heteroduplexes; Protein Binding; Pyrimidine Dimers; Thymine | 2004 |
Identification of novel mutations in ADAMTS13 in an adult patient with congenital thrombotic thrombocytopenic purpura.
Topics: ADAM Proteins; ADAMTS13 Protein; Adenine; Exons; Guanine; Heterozygote; Humans; Introns; Male; Metalloendopeptidases; Middle Aged; Mutation; Mutation, Missense; Phenotype; Protein Structure, Tertiary; Purpura, Thrombotic Thrombocytopenic; Recombinant Proteins; RNA Splicing; RNA, Messenger | 2004 |
The Werner syndrome protein confers resistance to the DNA lesions N3-methyladenine and O6-methylguanine: implications for WRN function.
Topics: 4-Nitroquinoline-1-oxide; Adenine; Alkylating Agents; Antineoplastic Agents; Apoptosis; Camptothecin; Carcinogens; Cells, Cultured; DNA Damage; DNA Helicases; DNA Replication; Drug Resistance; Exodeoxyribonucleases; Fibroblasts; Glioma; Guanine; Humans; Hydroxyurea; Netropsin; O(6)-Methylguanine-DNA Methyltransferase; Oligonucleotides, Antisense; RecQ Helicases; Werner Syndrome; Werner Syndrome Helicase | 2004 |
Interleukin 10 gene promoter polymorphisms are associated with chronic periodontitis.
Topics: Adenine; Adult; Chronic Disease; Cytosine; Female; Gene Frequency; Genetic Predisposition to Disease; Guanine; Haplotypes; Heterozygote; Humans; Interleukin-10; Male; Odds Ratio; Periodontitis; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Sequence Analysis, DNA; Sex Factors; Thymine | 2004 |
Lack of association between the TNF alpha G -308 A promoter polymorphism and periodontal disease.
Topics: Adenine; Adult; Aged; Alleles; Chronic Disease; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Guanine; Humans; Male; Middle Aged; Periodontitis; Polymorphism, Genetic; Promoter Regions, Genetic; Tumor Necrosis Factor-alpha | 2004 |
IL-10 promoter nt -1082A/G polymorphism and human papillomavirus infection in cytologic abnormalities of the uterine cervix.
Topics: Adenine; Alleles; Cervix Uteri; Cross-Sectional Studies; Female; Follow-Up Studies; Genetic Predisposition to Disease; Genotype; Guanine; Humans; Interleukin-10; Papillomavirus Infections; Polymorphism, Genetic; Promoter Regions, Genetic; White People | 2004 |
Analysis of the -1438 G/A polymorphism of the 5-HT2A serotonin receptor gene in bulimia nervosa patients with or without a history of anorexia nervosa.
Topics: Adenine; Adolescent; Adult; Anorexia Nervosa; Bulimia; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Guanine; Humans; Polymorphism, Single Nucleotide; Receptor, Serotonin, 5-HT2A | 2004 |
In vitro selection of drug-resistant varicella-zoster virus (VZV) mutants (OKA strain): differences between acyclovir and penciclovir?
Topics: 2-Aminopurine; Acyclovir; Adenine; Antiviral Agents; Arabinofuranosyluracil; Bromodeoxyuridine; Cidofovir; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Multiple, Viral; Drug Resistance, Viral; Foscarnet; Guanine; Herpesvirus 3, Human; Humans; Microbial Sensitivity Tests; Mutation; Organophosphonates; Phenotype; Selection, Genetic; Thymidine Kinase; Viral Proteins | 2004 |
Site-specific dissociation of DNA bases by slow electrons at early stages of irradiation.
Topics: Adenine; Cytosine; DNA; DNA Damage; Electrons; Guanine; Thymine | 2004 |
Association of interleukin-10 gene G-1082A polymorphism with the progression of primary glomerulonephritis.
Topics: Adenine; Adult; Disease Progression; Female; Gene Frequency; Genotype; Glomerulonephritis, IGA; Glomerulosclerosis, Focal Segmental; Guanine; Humans; Interleukin-10; Male; Middle Aged; Polymorphism, Genetic; Retrospective Studies | 2004 |
DNA sensor for o-dianisidine.
Topics: Adenine; Animals; Biosensing Techniques; Calibration; Carbon; Coloring Agents; Dianisidine; DNA; Electrochemistry; Electrodes; Guanine; Humans; Oxidation-Reduction; Potentiometry; Silver; Silver Compounds | 2004 |
A functional polymorphism (-347 G-->GA) in the E-cadherin gene is associated with colorectal cancer.
Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; Cadherins; Colorectal Neoplasms; Female; Guanine; Humans; Male; Middle Aged; Neoplasm Staging; Polymorphism, Genetic; Promoter Regions, Genetic; Reference Values | 2004 |
Genotoxicity of acrylamide and glycidamide.
Topics: Acrylamide; Adenine; Animals; Cell Culture Techniques; Cytosine; DNA Adducts; Dose-Response Relationship, Drug; Epoxy Compounds; Fibroblasts; Guanine; Humans; Mice; Mutagens; Mutation; Polymerase Chain Reaction; Respiratory Mucosa; Thymine; Transferases | 2004 |
Complexing properties of nucleic-acid constituents adenine and guanine complexes.
Topics: Adenine; Cobalt; Copper; Electrochemistry; Electron Spin Resonance Spectroscopy; Guanine; Magnetics; Nickel; Nucleic Acids; Organometallic Compounds; Spectrophotometry; Spectrophotometry, Infrared; Thermodynamics | 2004 |
Exploration of the conserved A+C wobble pair within the ribosomal peptidyl transferase center using affinity purified mutant ribosomes.
Topics: Adenine; Base Pairing; Base Sequence; Chromatography, Affinity; Cytosine; Escherichia coli; Guanine; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Peptide Chain Initiation, Translational; Peptidyl Transferases; Point Mutation; Ribosomes; RNA, Ribosomal, 23S; Uracil | 2004 |
The oxidative DNA base damage in testes of rats after intraperitoneal cadmium injection.
Topics: Adenine; Animals; Cadmium; DNA Damage; Guanine; Injections, Intraperitoneal; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Testis; Time Factors | 2004 |
C-reactive protein genotypes affect baseline, but not exercise training-induced changes, in C-reactive protein levels.
Topics: Adenine; Aged; Base Composition; Body Composition; C-Reactive Protein; Exercise Therapy; Female; Genetic Variation; Genotype; Guanine; Haplotypes; Humans; Male; Middle Aged; Point Mutation; Thymine | 2004 |
Identification of important chemical groups of the hut mRNA for HutP interactions that regulate the hut operon in Bacillus subtilis.
Topics: Adenine; Bacillus subtilis; Bacterial Proteins; Base Sequence; Binding Sites; Conserved Sequence; Electrophoretic Mobility Shift Assay; Gene Expression Regulation, Bacterial; Guanine; Histidine; Models, Molecular; Molecular Sequence Data; Operon; Regulatory Sequences, Ribonucleic Acid; RNA-Binding Proteins; RNA, Bacterial; RNA, Messenger; Uracil | 2004 |
Mutations in the lysyl oxidase gene not associated with intracranial aneurysm in central European families.
Topics: Adenine; Adult; Aged; Base Sequence; Europe; Female; Genetic Variation; Guanine; Humans; Intracranial Aneurysm; Male; Middle Aged; Mutation; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Protein-Lysine 6-Oxidase | 2004 |
Reversing DNA damage with a directional bias.
Topics: Adenine; Base Pair Mismatch; DNA; DNA Damage; DNA Repair; DNA-Directed DNA Polymerase; DNA-Directed RNA Polymerases; Guanine; Kinetics; Models, Chemical; O(6)-Methylguanine-DNA Methyltransferase; RNA, Messenger; Substrate Specificity; Transcription, Genetic | 2004 |
Novel intronic mutation of MEN1 gene causing familial isolated primary hyperparathyroidism.
Topics: Adenine; Animals; Base Sequence; COS Cells; Gene Expression; Germ-Line Mutation; Guanine; Heterozygote; Humans; Hyperparathyroidism; Introns; Male; Middle Aged; Pedigree; Proto-Oncogene Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2004 |
Four new cases of congenital secondary hypothyroidism due to a splice site mutation in the thyrotropin-beta gene: phenotypic variability and founder effect.
Topics: Adenine; Child; Child, Preschool; Congenital Hypothyroidism; Female; Founder Effect; Guanine; Haplotypes; Homozygote; Humans; Hypothyroidism; Infant; Infant, Newborn; Introns; Male; Mutation; Pedigree; Phenotype; Thyrotropin; Thyrotropin, beta Subunit | 2004 |
X-linked sex-determining region Y box 3 (SOX3) gene mutations are uncommon in men with idiopathic oligoazoospermic infertility.
Topics: Adenine; Chromosomes, Human, X; Cytosine; DNA-Binding Proteins; Gene Frequency; Genetic Linkage; Genetic Testing; Guanine; High Mobility Group Proteins; Humans; Infertility, Male; Male; Mutation; Oligospermia; SOXB1 Transcription Factors; Thymine; Transcription Factors | 2004 |
Double-proton transfer in adenine-thymine and guanine-cytosine base pairs. A post-Hartree-Fock ab initio study.
Topics: Adenine; Base Pairing; Cytosine; DNA; Guanine; Hydrogen Bonding; Kinetics; Models, Molecular; Protons; Surface Properties; Thermodynamics; Thymine | 2004 |
Conformationally constrained purine mimics. Incorporation of adenine and guanine into spirocyclic nucleosides.
Topics: Adenine; Guanine; Models, Molecular; Molecular Conformation; Molecular Mimicry; Molecular Structure; Nucleosides | 2004 |
N-terminus of the rat adenine glycosylase MYH affects excision rates and processing of MYH-generated abasic sites.
Topics: Adenine; Amino Acid Sequence; Animals; DNA; DNA Glycosylases; Guanine; Magnesium Chloride; Molecular Sequence Data; Protein Structure, Tertiary; Rats; Sequence Alignment; Sequence Deletion | 2004 |
Simple method for determining nucleobase pK(a) values by indirect labeling and demonstration of a pK(a) of neutrality in dsDNA.
Topics: Adenine; Base Pairing; Cytosine; DNA; DNA, Complementary; Guanine; Hydrogen-Ion Concentration; Kinetics; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Oligonucleotides; Thionucleotides; Thymine | 2004 |
Reaction intermediates in the catalytic mechanism of Escherichia coli MutY DNA glycosylase.
Topics: Adenine; Aspartic Acid; Binding Sites; Catalysis; Catalytic Domain; Crystallography, X-Ray; DNA; DNA Glycosylases; Dose-Response Relationship, Drug; Escherichia coli; Glutamic Acid; Guanine; Kinetics; Lysine; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Protein Conformation; Time Factors | 2004 |
Novel resistin promoter polymorphisms: association with serum resistin level in Japanese obese individuals.
Topics: Adenine; Adult; Asian People; Cytosine; Female; Guanine; Hormones, Ectopic; Humans; Linkage Disequilibrium; Male; Obesity; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Resistin; Transcription, Genetic | 2004 |
Electrostatic potential of nucleotide-free protein is sufficient for discrimination between adenine and guanine-specific binding sites.
Topics: Adenine; Binding Sites; Databases, Protein; Guanine; Hydrogen Bonding; In Vitro Techniques; Molecular Structure; Principal Component Analysis; Protein Binding; Proteins; Static Electricity; Thermodynamics | 2004 |
Association between the A-2518G polymorphism in the monocyte chemoattractant protein-1 gene and insulin resistance and Type 2 diabetes mellitus.
Topics: Adenine; Aged; Chemokine CCL2; Cohort Studies; Diabetes Mellitus, Type 2; Female; Glucose; Guanine; Homeostasis; Humans; Hyperinsulinism; Insulin Resistance; Male; Middle Aged; Polymorphism, Single Nucleotide | 2004 |
Relationship between a toll-like receptor-4 gene polymorphism, bacterial vaginosis-related flora and vaginal cytokine responses in pregnant women.
Topics: Adenine; Adult; Enzyme-Linked Immunosorbent Assay; Female; Genotype; Guanine; Humans; Interleukin-1; Membrane Glycoproteins; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Trimesters; Receptors, Cell Surface; Receptors, Interleukin-1; Toll-Like Receptor 4; Toll-Like Receptors; Vagina; Vaginosis, Bacterial | 2004 |
Two medium-chain acyl-coenzyme A synthetase genes, SAH and MACS1, are associated with plasma high-density lipoprotein cholesterol levels, but they are not associated with essential hypertension.
Topics: Adenine; Alleles; Asian People; Case-Control Studies; Cholesterol, HDL; Coenzyme A Ligases; Female; Gene Frequency; Guanine; Humans; Hypertension; Introns; Isoenzymes; Logistic Models; Male; Middle Aged; Polymorphism, Single Nucleotide; Thymine | 2004 |
Hydrogen-bonding-induced shifts of the excitation energies in nucleic acid bases: an interplay between electrostatic and electron density overlap effects.
Topics: Adenine; Base Pairing; Cytosine; Guanine; Hydrogen Bonding; Quantum Theory; Static Electricity; Thermodynamics; Thymine | 2004 |
Characterization of sea urchin transglutaminase, a protein regulated by guanine/adenine nucleotides.
Topics: Adenine; Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Catalytic Domain; Cloning, Molecular; Cysteine; DNA, Complementary; Dose-Response Relationship, Drug; Gene Library; Glutathione Transferase; GTP Phosphohydrolases; Guanine; Guanosine Triphosphate; Humans; Hydrolysis; In Situ Hybridization; Kinetics; Molecular Sequence Data; Paracentrotus; Plasmids; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Transglutaminases | 2004 |
Mutagenesis, genotoxicity, and repair of 1-methyladenine, 3-alkylcytosines, 1-methylguanine, and 3-methylthymine in alkB Escherichia coli.
Topics: Adenine; Base Sequence; Cytosine; DNA Adducts; DNA Damage; DNA Methylation; DNA Repair; DNA Replication; DNA, Bacterial; DNA, Single-Stranded; Escherichia coli; Escherichia coli Proteins; Genetic Techniques; Guanine; Mutagenesis; Nucleotides; SOS Response, Genetics; Thymine | 2004 |
Isolation of xanthine, guanine, adenine, proteose, oxalic acid, and glutathione from peanut kernels.
Topics: Adenine; Arachis; Glutathione; Guanine; Humans; Nuts; Oxalates; Oxalic Acid; Xanthine; Xanthines | 1950 |
Purine and pyrimidine contents of some desoxypentose nucleic acids.
Topics: Adenine; Animals; Cattle; Cytosine; Guanine; Horses; Nucleic Acids; Purines; Pyrimidines; Sheep; Thymine | 1950 |
A new synthesis of the purines adenine, hypoxanthine, xanthine, and isoguanine.
Topics: Adenine; Guanine; Hypoxanthine; Purines; Xanthine; Xanthines | 1950 |
Analysis of the conserved P9-G10.1 metal-binding motif in hammerhead ribozymes with an extra nucleotide inserted between A9 and G10.1 residues.
Topics: Adenine; Base Pairing; Binding Sites; Cadmium; Cations, Divalent; Guanine; Kinetics; Magnesium; Mutagenesis, Insertional; Nucleic Acid Conformation; RNA, Catalytic | 2004 |
An analogue of adenine that forms an "A:T" base pair of comparable stability to G:C.
Topics: Adenine; Base Pairing; Base Sequence; Cytosine; Guanine; Nucleic Acid Conformation; Thermodynamics; Thymine | 2004 |
The role of the reaction force to characterize local specific interactions that activate the intramolecular proton transfers in DNA basis.
Topics: Adenine; Cytosine; Guanine; Ion Transport; Isomerism; Oxygen; Protons; Static Electricity; Thymine | 2004 |
Tumor necrosis factor-alpha-308 promoter and p53 codon 72 gene polymorphisms in women with leiomyomas.
Topics: Adenine; Alleles; Case-Control Studies; Chromosomes, Human, Pair 17; Chromosomes, Human, Pair 6; Codon; Female; Gene Frequency; Genes, p53; Genetic Markers; Genetic Predisposition to Disease; Genotype; Guanine; Homozygote; Humans; Leiomyoma; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Prospective Studies; Tumor Necrosis Factor-alpha; Uterine Neoplasms | 2004 |
Isothermal titration calorimetry studies on the binding of DNA bases and PNA base monomers to gold nanoparticles.
Topics: Adenine; Calorimetry; Cytosine; Gold; Guanine; Nanostructures; Peptide Nucleic Acids; Spectrophotometry, Ultraviolet; Thymine | 2004 |
Effect of testosterone on purine nucleotide metabolism in rat liver.
Topics: Adenine; Androgens; Animals; Guanine; Hypoxanthine; Liver; Male; Models, Biological; Orchiectomy; Purine Nucleotides; Rats; Rats, Wistar; Testosterone | 2004 |
Tissue factor promotor polymorphism -603 A/G is associated with myocardial infarction.
Topics: Adenine; Alleles; Female; Guanine; Humans; Male; Middle Aged; Myocardial Infarction; Polymorphism, Genetic; Promoter Regions, Genetic; Thromboplastin | 2004 |
[Phenotypic variants of A3243G mitochondrial DNA mutation in a Hungarian family].
Topics: Adenine; Child; DNA Mutational Analysis; DNA, Mitochondrial; Female; Genetic Variation; Guanine; Hearing Loss; Humans; Hungary; MELAS Syndrome; Pedigree; Phenotype; Point Mutation; Siblings | 2004 |
Investigation on the IVS5 +5G --> a splice site mutation of HPS1 gene found in Japanese patients with Hermansky-Pudlak syndrome.
Topics: Adenine; Asian People; Child, Preschool; DNA, Recombinant; Guanine; Hermanski-Pudlak Syndrome; Humans; Introns; Male; Membrane Proteins; Mutation | 2004 |
Absence of association between transforming growth factor-beta1 promoter polymorphisms and hypodontia.
Topics: Adenine; Alleles; Anodontia; Base Pairing; Chi-Square Distribution; Cytosine; Gene Frequency; Genotype; Guanine; Humans; Odontogenesis; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Thymine; Transcription, Genetic; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2004 |
AUG codons at the beginning of protein coding sequences are frequent in eukaryotic mRNAs with a suboptimal start codon context.
Topics: Adenine; Animals; Arthropods; Base Sequence; Birds; Chromosome Mapping; Codon, Initiator; Eukaryotic Cells; Gene Frequency; Genetic Variation; Guanine; Humans; Mice; Molecular Sequence Data; Peptide Chain Initiation, Translational; Proteins; RNA, Messenger; Sequence Analysis, RNA; Species Specificity; Trinucleotide Repeats; Uracil | 2005 |
Genetics and variation in phenotype in Noonan syndrome.
Topics: Adenine; Adult; Child; Cytosine; Exons; Female; Genetic Variation; Genotype; Guanine; Humans; Infant; Intracellular Signaling Peptides and Proteins; Male; Mutation; Noonan Syndrome; Phenotype; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatases; SH2 Domain-Containing Protein Tyrosine Phosphatases; src Homology Domains; Thymine | 2004 |
The common -866G/A polymorphism in the promoter region of the UCP-2 gene is associated with reduced risk of type 2 diabetes in Caucasians from Italy.
Topics: Adenine; Adult; Aged; Diabetes Mellitus, Type 2; Female; Guanine; Humans; Ion Channels; Italy; Male; Membrane Transport Proteins; Middle Aged; Mitochondrial Proteins; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Risk Factors; Uncoupling Protein 2; White People | 2005 |
Mitochondrial myopathy and ophthalmoplegia in a sporadic patient with the 5698G-->A mitochondrial DNA mutation.
Topics: Adenine; Aged; Base Sequence; Chronic Disease; DNA, Mitochondrial; Electron Transport Complex IV; Guanine; Humans; Male; Muscle Fibers, Skeletal; Oculomotor Muscles; Ophthalmoplegia, Chronic Progressive External; Point Mutation; RNA, Transfer, Asn | 2004 |
Hyperinsulinism of infancy: novel ABCC8 and KCNJ11 mutations and evidence for additional locus heterogeneity.
Topics: Adenine; ATP-Binding Cassette Transporters; Chromosome Mapping; Cohort Studies; Electrophysiology; Genetic Heterogeneity; Guanine; Humans; Hyperinsulinism; Infant, Newborn; Islets of Langerhans; Mutation; Mutation, Missense; Pedigree; Potassium Channels; Potassium Channels, Inwardly Rectifying; Promoter Regions, Genetic; Receptors, Drug; Sulfonylurea Receptors | 2004 |
Relation of polymorphism within the C-reactive protein gene and plasma CRP levels.
Topics: Adenine; Aged; C-Reactive Protein; Cytosine; Exons; Female; Guanine; Humans; Introns; Male; Middle Aged; Polymorphism, Single Nucleotide; Thymine | 2005 |
A novel common single nucleotide polymorphism in the promoter region of the C-reactive protein gene associated with the plasma concentration of C-reactive protein.
Topics: Adenine; Aged; C-Reactive Protein; Case-Control Studies; Coronary Disease; Female; Genotype; Guanine; Humans; Linkage Disequilibrium; Male; Middle Aged; Osmolar Concentration; Polymorphism, Single Nucleotide; Promoter Regions, Genetic | 2005 |
Tumor necrosis factor alpha haplotypes versus tumor necrosis factor alpha -308 G/A polymorphism in the prediction of infliximab treatment efficacy in rheumatoid arthritis.
Topics: Adenine; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Rheumatoid; Guanine; Haplotypes; Humans; Infliximab; Polymorphism, Genetic; Treatment Outcome; Tumor Necrosis Factor-alpha | 2004 |
Direct assessment of interresidue forces in Watson-Crick base pairs using theoretical compliance constants.
Topics: Adenine; Base Pairing; Cytosine; DNA; Guanine; Models, Molecular; Thermodynamics; Thymine | 2004 |
Guanine-adenine DNA cross-linking by 1,2,3,4-diepoxybutane: potential basis for biological activity.
Topics: Adenine; DNA Adducts; Epoxy Compounds; Gas Chromatography-Mass Spectrometry; Guanine; Magnetic Resonance Spectroscopy; Mutagens; Stereoisomerism | 2004 |
Substrate discrimination by formamidopyrimidine-DNA glycosylase: distinguishing interactions within the active site.
Topics: Adenine; Catalytic Domain; Computer Simulation; DNA; DNA-Formamidopyrimidine Glycosylase; Guanine; Models, Molecular; Protein Structure, Tertiary; Substrate Specificity | 2004 |
Structural basis for discriminative regulation of gene expression by adenine- and guanine-sensing mRNAs.
Topics: Adenine; Bacillus subtilis; Crystallography, X-Ray; Gene Expression Regulation, Bacterial; Guanine; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Protein Folding; Protein Structure, Tertiary; Ribosomes; RNA, Bacterial; RNA, Messenger; Sensitivity and Specificity; Substrate Specificity; Vibrio vulnificus | 2004 |
The impact of CAG repeats in exon 1 of the androgen receptor on disease progression after prostatectomy.
Topics: Adenine; Age Factors; Aged; Black People; Cytosine; Disease Progression; Exons; Genotype; Guanine; Humans; Male; Middle Aged; Neoplasm Staging; Odds Ratio; Prostate-Specific Antigen; Prostatectomy; Prostatic Neoplasms; Receptors, Androgen; Survival Analysis; Trinucleotide Repeats; White People | 2005 |
Effects of substrate specificity on initiating the base excision repair of N-methylpurines by variant human 3-methyladenine DNA glycosylases.
Topics: Adenine; Animals; DNA Damage; DNA Glycosylases; DNA Repair; Dose-Response Relationship, Drug; Genetic Engineering; Guanine; Humans; Methyl Methanesulfonate; Mutagens; Saccharomyces cerevisiae; Substrate Specificity | 2005 |
Hydrogen bonding and covalent effects in binding of cisplatin to purine bases: ab initio and atoms in molecules studies.
Topics: Adenine; Cisplatin; Crystallography, X-Ray; Cytosine; Guanine; Hydrogen Bonding; Models, Chemical; Molecular Structure; Nucleic Acid Conformation; Organoplatinum Compounds; Purines; Thermodynamics | 2005 |
Scanning for MODY5 gene mutations in Chinese early onset or multiple affected diabetes pedigrees.
Topics: Adenine; Adult; Aged; Amino Acid Substitution; Asian People; Base Sequence; Case-Control Studies; Diabetes Mellitus; DNA-Binding Proteins; Exons; Female; Genetic Testing; Genetic Variation; Guanine; Hepatocyte Nuclear Factor 1-beta; Heterozygote; Humans; Introns; Male; Middle Aged; Molecular Sequence Data; Mutation; Pedigree; Phenylalanine; Promoter Regions, Genetic; Serine; Transcription Factors | 2004 |
A pilot study of mitochondrial DNA point mutation A3243G in a sample of Croatian patients having type 2 diabetes mellitus associated with maternal inheritance.
Topics: Adenine; Adult; Age of Onset; Aged; Case-Control Studies; Croatia; Diabetes Mellitus, Type 2; DNA; DNA, Mitochondrial; Female; Gene Frequency; Genetic Testing; Guanine; Humans; Male; Middle Aged; Mothers; Mouth Mucosa; Pilot Projects; Point Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length | 2004 |
Mutations in a novel gene, encoding a single transmembrane domain protein are associated with familial glucocorticoid deficiency type 2.
Topics: Adenine; Chromosomes, Human, Pair 21; Glucocorticoids; Guanine; Homozygote; Humans; Introns; Mutation; Protein Transport; Steroid Metabolism, Inborn Errors; Thymine | 2004 |
DNA adducts derived from administration of acrylamide and glycidamide to mice and rats.
Topics: Acrylamide; Adenine; Administration, Oral; Animals; DNA Adducts; Epoxy Compounds; Female; Guanine; Injections, Intraperitoneal; Male; Mice; Mice, Inbred Strains; Mutagens; Rats; Rats, Inbred F344; Tissue Distribution | 2005 |
Interleukin-10 -1082 G/A polymorphism and risk of death or bronchopulmonary dysplasia in ventilated very low birth weight infants.
Topics: Adenine; Alleles; Bronchopulmonary Dysplasia; Case-Control Studies; Cause of Death; Ethnicity; Female; Gene Frequency; Genotype; Guanine; Heterozygote; Homozygote; Humans; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight; Interleukin-10; Male; Polymorphism, Single Nucleotide; Prospective Studies; Respiration, Artificial; Risk Factors; Sex Factors; Trachea | 2005 |
G125A single-nucleotide polymorphism in the human BAX promoter affects gene expression.
Topics: Adenine; Algorithms; Base Sequence; bcl-2-Associated X Protein; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Genes, Reporter; Guanine; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Luciferases; Plasmids; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Proto-Oncogene Proteins c-bcl-2 | 2005 |
Androgen receptor trinucleotide polymorphism in leiomyoma.
Topics: Adenine; Alleles; Cytosine; DNA; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Guanine; Humans; Leiomyoma; Microsatellite Repeats; Polymerase Chain Reaction; Polymorphism, Genetic; Receptors, Androgen; Risk Factors; Taiwan; Trinucleotide Repeats; Uterine Neoplasms | 2004 |
Solution structure of an RNA internal loop with three consecutive sheared GA pairs.
Topics: Adenine; Base Pairing; Base Sequence; Guanine; Hydrogen Bonding; Models, Molecular; Nucleic Acid Conformation; Oligoribonucleotides; RNA; Solutions; Thermodynamics | 2005 |
Congenital abnormalities of cranial nerve development: overview, molecular mechanisms, and further evidence of heterogeneity and complexity of syndromes with congenital limitation of eye movements.
Topics: Adenine; Adolescent; Adult; Amino Acid Substitution; Arginine; Child; Child, Preschool; Chromosome Mapping; Chromosomes, Human, Pair 11; Cranial Nerves; Female; Fibrosis; Genes, Recessive; Genetic Variation; Glutamine; Guanine; Humans; Kinesins; Male; Mobius Syndrome; Mutation; Nerve Tissue Proteins; Oculomotor Muscles; Ophthalmoplegia; Pedigree; Phenotype; Scoliosis; Syndrome | 2004 |
Experimental demonstration of T:(G:G:G:G):T hexad and T:A:A:T tetrad alignments within a DNA quadruplex stem.
Topics: Adenine; Base Sequence; Deuterium Exchange Measurement; DNA; G-Quadruplexes; Guanine; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Nucleic Acid Heteroduplexes; Protons; Sequence Alignment; Thionucleotides; Thymine | 2005 |
Electrospray ionization mass spectrometric study of purine base-cisplatin complexes.
Topics: Adenine; Antineoplastic Agents; Cisplatin; Guanine; Spectrometry, Mass, Electrospray Ionization; Thermodynamics | 2005 |
[Raman spectroscopic study on the influence of ultraviolet radiation on calf thymus DNA in aqueous solution].
Topics: Adenine; Animals; Cattle; Cytosine; DNA; DNA Damage; Guanine; Hydrogen Bonding; Photochemistry; Spectrum Analysis, Raman; Thymine; Ultraviolet Rays | 2004 |
[Fourier transform infrared spectra analysis of nucleic acid in human breast tissue].
Topics: Adenine; Breast Neoplasms; Female; Guanine; Humans; Nucleic Acids; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis | 2004 |
Identification of a recurrent mutation in keratin 17 in a Japanese family with pachyonychia congenita type 2.
Topics: Adenine; Adult; Amino Acid Sequence; Asian People; Base Sequence; Guanine; Humans; Keratins; Male; Molecular Sequence Data; Mutation, Missense; Nail Diseases; Pedigree | 2005 |
Accurate measurement of 15N-13C residual dipolar couplings in nucleic acids.
Topics: Adenine; Bacteriophage Pf1; Base Pairing; Base Sequence; Carbon Isotopes; Cytidine; Deuterium; Escherichia coli; Fourier Analysis; Guanine; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acids; Protons; Quantum Theory; Reproducibility of Results; RNA, Bacterial; Sensitivity and Specificity; Sequence Homology, Nucleic Acid; Uridine | 2005 |
Characterization of a new allele of Ames waltzer generated by ENU mutagenesis.
Topics: Acoustic Stimulation; Adenine; Alleles; Animals; Auditory Threshold; Base Sequence; Cadherin Related Proteins; Cadherins; Deafness; DNA Mutational Analysis; Ethylnitrosourea; Evoked Potentials, Auditory, Brain Stem; Female; Guanine; Hair Cells, Auditory, Inner; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Microscopy, Electron, Scanning; Mutagens; Mutation; Organ of Corti; Phenotype; Protein Precursors; Vestibular Diseases | 2005 |
The extent of ossification of posterior longitudinal ligament of the spine associated with nucleotide pyrophosphatase gene and leptin receptor gene polymorphisms.
Topics: Adenine; Case-Control Studies; Female; Gene Deletion; Genetic Predisposition to Disease; Genetic Variation; Guanine; Humans; Introns; Longitudinal Ligaments; Male; Middle Aged; Ossification of Posterior Longitudinal Ligament; Polymorphism, Genetic; Pyrophosphatases; Radiography; Receptors, Cell Surface; Receptors, Leptin; Severity of Illness Index; Spine; Thymine | 2005 |
Tumor necrosis factor receptor gene polymorphisms in Crohn's disease: association with clinical phenotypes.
Topics: Adenine; Adult; Cohort Studies; Colitis; Crohn Disease; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Guanine; Humans; Ileitis; Intracellular Signaling Peptides and Proteins; Male; Mutation, Missense; Nod2 Signaling Adaptor Protein; Phenotype; Polymorphism, Single Nucleotide; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; Tumor Necrosis Factor-alpha | 2005 |
Clinico-pathologic findings in medullary cystic kidney disease type 2.
Topics: Adenine; Child; Guanine; Humans; Immunohistochemistry; Kidney; Male; Mucoproteins; Polycystic Kidney, Autosomal Dominant; Polymorphism, Single Nucleotide; Staining and Labeling; Uromodulin | 2005 |
Guanine-adenine bias: a general property of retroid viruses that is unrelated to host-induced hypermutation.
Topics: Adenine; APOBEC-3G Deaminase; Codon; Cytidine Deaminase; Cytosine Deaminase; Genes, vif; Guanine; Humans; Mutagenesis; Mutation; Nucleoside Deaminases; Proteins; Repressor Proteins; Retroviridae; Transcription, Genetic; Virus Replication | 2005 |
Discrimination of single-nucleotide alterations by G-specific fluorescence quenching.
Topics: Adenine; Base Pair Mismatch; Biosensing Techniques; Fluorescence; Fluorescent Dyes; Guanine; Nucleotides; Oligonucleotides; Pyrenes; Spectrometry, Fluorescence; Thymidine | 2005 |
Analysis of the 5q31-q33 locus shows an association between IL13-1055C/T IL-13-591A/G polymorphisms and Schistosoma haematobium infections.
Topics: Adenine; Adult; Animals; Antigens, Helminth; Child; Chromosomes, Human, Pair 5; Cytosine; Genetic Markers; Genotype; Guanine; Humans; Interleukin-13; Interleukin-5; Multivariate Analysis; Nuclear Family; Nuclear Proteins; Polymorphism, Single Nucleotide; Polymorphism, Single-Stranded Conformational; Protein Binding; Schistosomiasis haematobia; Thymine | 2005 |
Analysis of the 2.0 A crystal structure of the protein-DNA complex of the human PDEF Ets domain bound to the prostate specific antigen regulatory site.
Topics: 3' Flanking Region; 5' Flanking Region; Adenine; Amino Acid Sequence; Crystallography, X-Ray; DNA-Binding Proteins; Guanine; Humans; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Prostate-Specific Antigen; Protein Binding; Protein Structure, Tertiary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ets; Sequence Analysis, DNA; Transcription Factors | 2005 |
Association of the myeloperoxidase -468G-->A polymorphism with gastric inflammation and duodenal ulcer risk.
Topics: Adenine; Adult; Aged; Duodenal Ulcer; Female; Gastritis; Genetic Predisposition to Disease; Guanine; Humans; Male; Middle Aged; Peroxidase | 2005 |
Role of an active site adenine in hairpin ribozyme catalysis.
Topics: Adenine; Base Pairing; Base Sequence; Binding Sites; Catalysis; Guanine; Hydrogen-Ion Concentration; Models, Molecular; Molecular Sequence Data; Mutation; Nucleic Acid Conformation; Oligonucleotides; RNA, Catalytic | 2005 |
Theoretical study of molecular recognition by Hoechst 33258 derivatives.
Topics: Adenine; Benzimidazoles; Bisbenzimidazole; Crystallography, X-Ray; Cytosine; DNA; Fluorescent Dyes; Guanine; Hydrogen; Hydrogen Bonding; Ligands; Macromolecular Substances; Models, Chemical; Nucleic Acid Conformation; Octanols; Protein Binding; Protein Conformation; Spectrophotometry; Static Electricity; Thermodynamics; Thymine; Water | 2005 |
NMR structure and Mg2+ binding of an RNA segment that underlies the L7/L12 stalk in the E.coli 50S ribosomal subunit.
Topics: Adenine; Base Pairing; Base Sequence; Binding Sites; Escherichia coli; Guanine; Hydrogen Bonding; Magnesium; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Protons; Ribosomal Proteins; RNA, Bacterial; RNA, Ribosomal, 23S | 2005 |
Androgen receptor gene CAG length polymorphism in women with polycystic ovary syndrome.
Topics: Adenine; Case-Control Studies; Chi-Square Distribution; Cytosine; Female; Guanine; Humans; Polycystic Ovary Syndrome; Polymorphism, Genetic; Receptors, Androgen; Retrospective Studies; Trinucleotide Repeats | 2005 |
Loss of G-A base pairs is insufficient for achieving a large opening of U4 snRNA K-turn motif.
Topics: Adenine; Base Pairing; Computer Simulation; Guanine; Models, Molecular; Nucleic Acid Conformation; Ribonucleoproteins, Small Nuclear; RNA, Small Nuclear | 2005 |
Frasier syndrome comes full circle: genetic studies performed in an original patient.
Topics: Adenine; Denys-Drash Syndrome; DNA Mutational Analysis; Female; Genes, Wilms Tumor; Gonadal Dysgenesis, 46,XY; Guanine; Humans; Introns; Middle Aged; Point Mutation; Polymerase Chain Reaction | 2005 |
TNF promoter polymorphisms and modulation of growth retardation and disease severity in pediatric Crohn's disease.
Topics: Adenine; Adolescent; Child; Cohort Studies; Crohn Disease; Cytosine; Female; Genotype; Growth Disorders; Guanine; Humans; Male; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Severity of Illness Index; Thymine; Tumor Necrosis Factor-alpha | 2005 |
Upstream transcription factor-1 gene polymorphism is associated with increased adipocyte lipolysis.
Topics: Adenine; Adipocytes; Adult; Alleles; Cohort Studies; Cytosine; DNA-Binding Proteins; Female; Gene Frequency; Guanine; Haplotypes; Humans; Linkage Disequilibrium; Lipolysis; Middle Aged; Obesity; Polymorphism, Genetic; Polymorphism, Single Nucleotide; RNA, Messenger; Subcutaneous Tissue; Thymine; Transcription Factors; Upstream Stimulatory Factors | 2005 |
An investigation of prebiotic purine synthesis from the hydrolysis of HCN polymers.
Topics: Adenine; Cyanides; Evolution, Chemical; Guanine; Hydrogen Cyanide; Hydrolysis; Origin of Life; Polymers | 2005 |
The role of factor V Leiden and prothrombin G20210A mutations in sudden sensorineural hearing loss.
Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; Case-Control Studies; Child; Factor V; Female; Guanine; Hearing Loss, Sensorineural; Hearing Loss, Sudden; Humans; Male; Middle Aged; Mutation; Prothrombin | 2005 |
Murine cytomegalovirus resistant to antivirals has genetic correlates with human cytomegalovirus.
Topics: Acyclovir; Adenine; Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Ganciclovir; Guanine; Humans; Mice; Models, Molecular; Molecular Sequence Data; Muromegalovirus; Mutation; Organophosphonates; Protein Kinases; Sequence Alignment; Valacyclovir; Valine; Virus Replication | 2005 |
DNA methylation, cell proliferation, and histopathology in rats following repeated inhalation exposure to dimethyl sulfate.
Topics: Adenine; Administration, Inhalation; Alkylating Agents; Animals; Body Weight; Cell Proliferation; DNA; DNA Adducts; DNA Methylation; Guanine; Male; Methylation; Models, Biological; Mutagens; Olfactory Mucosa; Purines; Rats; Risk; Sulfuric Acid Esters | 2004 |
TNF-alpha G-308A polymorphism is associated with rheumatic fever and correlates with increased TNF-alpha production.
Topics: Adenine; Adolescent; Adult; Alleles; Child; DNA Mutational Analysis; Gene Frequency; Genetic Predisposition to Disease; Guanine; Humans; Middle Aged; Polymorphism, Single Nucleotide; Rheumatic Fever; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Up-Regulation | 2005 |
A common mutation in an organic anion transporter gene, SLC22A12, is a suppressing factor for the development of gout.
Topics: Adenine; Adult; Carrier Proteins; Case-Control Studies; Female; Gene Frequency; Genotype; Gout; Guanine; Heterozygote; Humans; Male; Middle Aged; Mutation; Organic Anion Transporters; Organic Cation Transport Proteins; Uric Acid | 2005 |
Models of putative (AH)G(AH)G nucleobase quartets.
Topics: Adenine; Crystallography, X-Ray; Guanine; Hydrogen Bonding; Models, Molecular; Xanthine | 2005 |
High frequency of the IVS2-2A>G DNA sequence variation in SLC26A5, encoding the cochlear motor protein prestin, precludes its involvement in hereditary hearing loss.
Topics: Adenine; Alleles; Alternative Splicing; Animals; Anion Transport Proteins; Cochlea; DNA, Mitochondrial; Exons; Genetic Variation; Guanine; Hair Cells, Vestibular; Hearing Loss; Humans; Introns; Mice; Molecular Motor Proteins; Pan troglodytes; Proteins; Rats; RNA Splice Sites; RNA, Ribosomal; Sequence Alignment; Sequence Analysis, DNA; Sulfate Transporters; Zebrafish; Zebrafish Proteins | 2005 |
Chronic hepatitis B--treatment with nucleoside analogues.
Topics: Adenine; Drug Resistance; Drug Therapy, Combination; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Liver Transplantation; Nucleosides; Organophosphonates; Reverse Transcriptase Inhibitors; Time Factors | 2005 |
Simultaneous determination of adenine and guanine in ruminant bacterial pellets by ion-pair HPLC.
Topics: Adenine; Animals; Bacteria; Chromatography, High Pressure Liquid; Guanine; Rumen | 2005 |
Polymerization past the N2-isopropylguanine and the N6-isopropyladenine DNA lesions with the translesion synthesis DNA polymerases eta and iota and the replicative DNA polymerase alpha.
Topics: Adenine; Base Sequence; Catalysis; DNA; DNA Damage; DNA Polymerase I; DNA Polymerase iota; DNA-Directed DNA Polymerase; Guanine; Humans; Kinetics; Molecular Sequence Data | 2005 |
Interleukin 6 G-174C polymorphism influences outcome following coronary revascularization surgery.
Topics: Adenine; Aged; Alleles; Atrial Fibrillation; Blood Loss, Surgical; Coronary Artery Bypass; Coronary Disease; Female; Genetic Predisposition to Disease; Genotype; Guanine; Homozygote; Humans; Incidence; Interleukin-6; Length of Stay; Male; Middle Aged; Polymorphism, Genetic; Postoperative Period; Prospective Studies; Severity of Illness Index; Treatment Outcome | 2005 |
Tumor necrosis factor-alpha promoter polymorphism is associated with susceptibility to oral squamous cell carcinoma.
Topics: Adenine; Alleles; Base Sequence; Carcinoma, Squamous Cell; Case-Control Studies; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Guanine; Humans; Male; Middle Aged; Mouth Neoplasms; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Promoter Regions, Genetic; Tumor Necrosis Factor-alpha | 2005 |
Alternate polypurine tracts (PPTs) affect the rous sarcoma virus RNase H cleavage specificity and reveal a preferential cleavage following a GA dinucleotide sequence at the PPT-U3 junction.
Topics: Adenine; Avian Sarcoma Viruses; Guanine; Purines; Ribonuclease H; RNA-Directed DNA Polymerase; Terminal Repeat Sequences; Virus Replication | 2005 |
A novel somatic mutation of the 3beta-hydroxysteroid dehydrogenase gene in sporadic cutaneous verruciform xanthoma.
Topics: 3-Hydroxysteroid Dehydrogenases; Adenine; Aged; Aged, 80 and over; Arginine; Base Sequence; Exons; Female; Guanine; Histidine; Humans; Male; Middle Aged; Molecular Sequence Data; Mutation, Missense; Skin Neoplasms; Xanthomatosis | 2005 |
Direct repair of the exocyclic DNA adduct 1,N6-ethenoadenine by the DNA repair AlkB proteins.
Topics: Adenine; AlkB Homolog 3, Alpha-Ketoglutarate-Dependent Dioxygenase; Alkylation; Cytosine; Dioxygenases; DNA; DNA Adducts; DNA Repair; DNA Repair Enzymes; DNA-Binding Proteins; Escherichia coli Proteins; Guanine; Humans; Hydrogen-Ion Concentration; Iron; Mixed Function Oxygenases; Molecular Structure; Time Factors | 2005 |
DNA damage levels and biochemical repair capacities associated with XRCC1 deficiency.
Topics: Adenine; Animals; Binding Sites; Cell Extracts; Cell Line; Cricetinae; Cytosine; DNA Damage; DNA Repair; DNA-Binding Proteins; Female; Guanine; Mutation; Ovary; Time Factors; Uracil; X-ray Repair Cross Complementing Protein 1 | 2005 |
Community-based epidemiology of hepatitis B virus infection in West Bengal, India: prevalence of hepatitis B e antigen-negative infection and associated viral variants.
Topics: Adenine; Adolescent; Adult; Child; Codon, Terminator; Demography; DNA, Viral; Genetic Variation; Genotype; Guanine; Hepatitis B; Hepatitis B Antibodies; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; India; Middle Aged; Mutation; Prevalence; Promoter Regions, Genetic; Seroepidemiologic Studies | 2005 |
Detection of chlorinated DNA and RNA nucleosides by HPLC coupled to tandem mass spectrometry as potential biomarkers of inflammation.
Topics: Adenine; Biomarkers; Cell Line, Tumor; Chromatography, High Pressure Liquid; Cytosine; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Guanine; Humans; Inflammation; Leukocytes; Nucleosides; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization | 2005 |
Role of tumor necrosis factor-alpha and interleukin-10 gene polymorphisms in irritable bowel syndrome.
Topics: Adenine; Adult; Constipation; Diarrhea; Female; Gastroenteritis; Gene Frequency; Genotype; Guanine; Heterozygote; Homozygote; Humans; Inflammation Mediators; Interleukin-10; Irritable Bowel Syndrome; Male; Middle Aged; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Tumor Necrosis Factor-alpha | 2005 |
Dysregulation of peripheral cytokine production in irritable bowel syndrome.
Topics: Adenine; Gastroenteritis; Genotype; Guanine; Humans; Immunity, Mucosal; Inflammation Mediators; Interleukin-10; Irritable Bowel Syndrome; Tumor Necrosis Factor-alpha | 2005 |
Efficient primer strand extension beyond oxadiazole carboxamide nucleobases.
Topics: Adenine; Cytosine; DNA Primers; Guanine; Molecular Structure; Oxadiazoles; Thymine | 2005 |
Condensation of nucleobases at mercury/aqueous solution interface--a structural perspective using hydrogen bonding considerations.
Topics: Adenine; Adenosine; Adsorption; Cytosine; Electrodes; Electrolytes; Guanine; Hydrogen Bonding; Mercury; Potassium; Purines; Pyrimidines; Sodium; Solutions; Thermodynamics; Thiouracil; Thymine; Uracil; Water | 2002 |
Involvement of 16S rRNA nucleotides G1338 and A1339 in discrimination of initiator tRNA.
Topics: Adenine; Escherichia coli Proteins; Gene Expression; Guanine; Mutation; Prokaryotic Initiation Factor-2; Prokaryotic Initiation Factor-3; Protein Biosynthesis; Ribosomes; RNA, Ribosomal, 16S; RNA, Transfer, Met | 2005 |
Oxidative DNA damage and antioxidant defenses in the European common lizard (Lacerta vivipara) in supercooled and frozen states.
Topics: Adaptation, Physiological; Adenine; Aldehydes; Animals; Antioxidants; Catalase; DNA Damage; Freezing; Glutathione Peroxidase; Guanine; Lipid Peroxidation; Liver; Lizards; Malondialdehyde; Muscles; Oxidative Stress; Superoxide Dismutase | 2006 |
Identification of three major DNA adducts formed by the carcinogenic air pollutant 3-nitrobenzanthrone in rat lung at the C8 and N2 position of guanine and at the N6 position of adenine.
Topics: Adenine; Animals; Benz(a)Anthracenes; DNA Adducts; Female; Guanine; Lung; Lung Neoplasms; Phosphorus Radioisotopes; Rats; Rats, Sprague-Dawley; Vehicle Emissions | 2006 |
Clinical, genetic, and biochemical findings in two siblings with Papillon-Lefèvre Syndrome.
Topics: Adenine; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Local; Cathepsin C; Cathepsin G; Cathepsins; Child; Child, Preschool; Chlorhexidine; Dental Scaling; Drug Combinations; Female; Genes, Recessive; Guanine; Humans; Leukocyte Elastase; Metronidazole; Mutation; Papillon-Lefevre Disease; Root Planing; Serine Endopeptidases | 2005 |
Characterization of novel Na+-dependent nucleobase transport systems at the blood-testis barrier.
Topics: Adenine; Animals; Biological Transport; Blood-Testis Barrier; Cytosine; Guanine; Hypoxanthine; Kinetics; Male; Meglumine; Nucleobase Transport Proteins; Nucleoside Transport Proteins; Purine Nucleosides; Pyrimidine Nucleosides; Rats; Rats, Inbred Strains; Sertoli Cells; Sodium; Thioinosine; Thymine; Uracil; Uridine | 2006 |
Substitutions in the reverse transcriptase and protease genes of HIV-1 subtype B in untreated individuals and patients treated with antiretroviral drugs.
Topics: Adenine; Anti-Retroviral Agents; Base Sequence; Guanine; HIV Infections; HIV Protease; HIV Reverse Transcriptase; HIV-1; Humans | 2005 |
Restriction of foamy viruses by APOBEC cytidine deaminases.
Topics: Adenine; Animals; APOBEC-3G Deaminase; Base Sequence; Cell Line; Cytidine Deaminase; Genome, Viral; Guanine; Humans; Macaca; Mice; Molecular Sequence Data; Mutation; Nucleoside Deaminases; Repressor Proteins; Species Specificity; Spumavirus; Virus Replication | 2006 |
Electron inelastic mean free path formula and CSDA-range calculation in biological compounds for low and intermediate energies.
Topics: Adenine; Base Pairing; Cytosine; Guanine; Models, Chemical; Scattering, Radiation; Thymine | 2006 |
Association of CTLA-4 gene polymorphism with oral squamous cell carcinoma.
Topics: Adenine; Adult; Age Factors; Aged; Aged, 80 and over; Antigens, CD; Antigens, Differentiation; Carcinoma, Squamous Cell; Clonal Anergy; CTLA-4 Antigen; Exons; Female; Gene Frequency; Genotype; Guanine; Humans; Immune Tolerance; Immunoglobulin Fc Fragments; Lymphocyte Activation; Male; Middle Aged; Mouth Neoplasms; Phenotype; Polymorphism, Genetic; Survival Rate; T-Lymphocytes | 2006 |
Contributions of PTCH gene variants to isolated cleft lip and palate.
Topics: Adenine; Alleles; Basal Cell Nevus Syndrome; Case-Control Studies; Cleft Lip; Cleft Palate; Cytosine; Exons; Female; Genetic Linkage; Genetic Variation; Guanine; Haplotypes; Humans; Linkage Disequilibrium; Lod Score; Male; Microsatellite Repeats; Mutation, Missense; Patched Receptors; Patched-1 Receptor; Polymorphism, Single Nucleotide; Receptors, Cell Surface; Thymine | 2006 |
L-carnitine suppresses the onset of neuromuscular degeneration and increases the life span of mice with familial amyotrophic lateral sclerosis.
Topics: Adenine; Amyotrophic Lateral Sclerosis; Animals; Apoptosis; Carnitine; Disease Progression; Female; Guanine; Hindlimb; Humans; Injections, Subcutaneous; Longevity; Male; Mice; Mice, Transgenic; Muscle Proteins; Muscle, Skeletal; Mutation; Nerve Degeneration; Nerve Tissue Proteins; Oxidation-Reduction; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1; Vitamin B Complex | 2006 |
Poleta, Polzeta and Rev1 together are required for G to T transversion mutations induced by the (+)- and (-)-trans-anti-BPDE-N2-dG DNA adducts in yeast cells.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adenine; Deoxyguanine Nucleotides; DNA Adducts; DNA Damage; DNA-Directed DNA Polymerase; DNA, Fungal; Guanine; Models, Genetic; Mutagenesis; Nucleotidyltransferases; Point Mutation; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Thymine | 2006 |
Do Craniosynostosis syndrome phenotypes with both FGFR2 and TWIST mutations have a worse clinical outcome?
Topics: Acrocephalosyndactylia; Adenine; Adolescent; Arginine; Child, Preschool; Craniofacial Dysostosis; Craniosynostoses; Cysteine; Cytosine; DNA Transposable Elements; Female; Follow-Up Studies; Guanine; Humans; Male; Mutation; Receptor, Fibroblast Growth Factor, Type 2; Sequence Deletion; Serine; Syndrome; Thymine; Treatment Outcome; Tryptophan; Twist-Related Protein 1 | 2006 |
The small planarization barriers for the amino group in the nucleic acid bases.
Topics: Adenine; Base Pairing; Cytosine; Guanine; Hydrogen Bonding; Nucleic Acid Conformation; Nucleic Acids; Thermodynamics | 2006 |
Description of two new cathepsin C gene mutations in patients with Papillon-Lefèvre syndrome.
Topics: Adenine; Cathepsin C; Child; Child, Preschool; Codon, Nonsense; Conserved Sequence; Cytosine; DNA; Exons; Female; Gene Deletion; Guanine; Heteroduplex Analysis; Heterozygote; Histidine; Homozygote; Humans; Introns; Male; Mutation; Papillon-Lefevre Disease; Pedigree; Phenotype; Sequence Analysis, DNA; Thymine | 2006 |
Unexpected pathogenic mechanism of a novel mutation in the coding sequence of SPG4 (spastin).
Topics: Adenine; Adenosine Triphosphatases; Adult; Base Sequence; Cell Line; DNA Mutational Analysis; Gait; Genes, Dominant; Guanine; Humans; Leg; Male; Microtubules; Muscle Tonus; Muscle Weakness; Mutation, Missense; Spastic Paraplegia, Hereditary; Spastin; Transfection | 2006 |
Simulation of DNA bases in water: Comparison of the Monte Carlo algorithm with molecular mechanics force fields.
Topics: Adenine; Algorithms; Cytosine; DNA; Guanine; Models, Chemical; Monte Carlo Method; Thermodynamics; Thymine; Water | 2006 |
N6-methyl-AMP aminohydrolase activates N6-substituted purine acyclic nucleoside phosphonates.
Topics: Adenine; Aminohydrolases; Animals; Catalysis; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Guanine; In Vitro Techniques; Liver; Organophosphonates; Organophosphorus Compounds; Prodrugs; Rats; Rats, Sprague-Dawley | 2006 |
Sutural cataract associated with a mutation in the ferritin light chain gene (FTL) in a family of Indian origin.
Topics: 5' Untranslated Regions; Adenine; Apoferritins; Cataract; Child, Preschool; Chromosomes, Human, Pair 19; Conserved Sequence; Female; Ferritins; Genetic Linkage; Guanine; Haplotypes; Humans; India; Lens Nucleus, Crystalline; Lod Score; Male; Mutation; Pedigree; Peptides; Response Elements; Syndrome | 2006 |
Structure of purine-purine mispairs during misincorporation and extension by Escherichia coli DNA polymerase I.
Topics: Adenine; Base Pair Mismatch; Base Sequence; DNA Polymerase I; DNA Replication; Escherichia coli; Guanine; Hydrogen Bonding; Kinetics; Molecular Sequence Data; Nucleic Acid Conformation; Purines; Structure-Activity Relationship | 2006 |
Base sequence effects on transport in DNA.
Topics: Adenine; Algorithms; Base Sequence; Cytosine; DNA; DNA Damage; Energy Transfer; Guanine; Oxidative Stress; Temperature; Thymine | 2006 |
Consecutive GA pairs stabilize medium-size RNA internal loops.
Topics: Adenine; Base Pairing; Guanine; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; RNA; Thermodynamics; Ultraviolet Rays | 2006 |
Adduct-specific monoclonal antibodies for the measurement of cisplatin-induced DNA lesions in individual cell nuclei.
Topics: Adenine; Animals; Antibodies, Monoclonal; Antibody Specificity; Antineoplastic Agents; Cell Nucleus; Cisplatin; DNA Adducts; DNA Damage; DNA Repair; Fluorescent Antibody Technique, Indirect; Guanine; Humans; Hybridomas; Immunoassay; Jurkat Cells; Male; Mice; Mice, Inbred C57BL; Stomach Neoplasms | 2006 |
A to G transitions at 260, 386 and 437 in DAZL gene are not associated with spermatogenic failure in Indian population.
Topics: Adenine; Guanine; Humans; India; Male; Oligospermia; Point Mutation; RNA-Binding Proteins | 2006 |
A case-control study investigating the role of sulfotransferase 1A1 polymorphism in head and neck cancer.
Topics: Adenine; Alleles; Arginine; Arylsulfotransferase; Carcinoma, Squamous Cell; Case-Control Studies; Codon; Female; Guanine; Head and Neck Neoplasms; Histidine; Humans; Life Style; Male; Middle Aged; Polymorphism, Genetic; Risk Factors | 2006 |
Genotype distribution of estrogen receptor-alpha, catechol-O-methyltransferase, and cytochrome P450 17 gene polymorphisms in Caucasian women with uterine leiomyomas.
Topics: Adenine; Adult; Case-Control Studies; Catechol O-Methyltransferase; Cytosine; Estrogen Receptor alpha; Female; Genetic Predisposition to Disease; Genotype; Guanine; Humans; Introns; Leiomyoma; Middle Aged; Polymorphism, Single Nucleotide; Prospective Studies; Steroid 17-alpha-Hydroxylase; Thymine; Uterine Neoplasms; White People | 2006 |
Preimplantation genetic diagnosis of leukocyte adhesion deficiency type I.
Topics: Adenine; Adult; Cytosine; Embryo Transfer; Exons; Female; Fertilization in Vitro; Guanine; Humans; Leukocyte-Adhesion Deficiency Syndrome; Male; Pregnancy; Pregnancy Outcome; Preimplantation Diagnosis; Thymine | 2006 |
Antiviral options for the treatment of chronic hepatitis B.
Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Organophosphonates | 2006 |
An intronic polymorphism associated with increased XRCC1 expression, reduced apoptosis and familial breast cancer.
Topics: Adenine; Adult; Apoptosis; Base Sequence; Benzo(a)pyrene; Breast Neoplasms; Carcinogens; Case-Control Studies; Cell Line, Tumor; DNA-Binding Proteins; Female; Gene Expression Regulation, Neoplastic; Gene Frequency; Genotype; Guanine; Humans; Introns; Logistic Models; Mesylates; Middle Aged; Molecular Sequence Data; Odds Ratio; Pedigree; Polymorphism, Single Nucleotide; Risk Factors; RNA, Messenger; Up-Regulation; X-ray Repair Cross Complementing Protein 1 | 2006 |
Tetraarylporphyrin as a selective molecular cap for non-Watson-Crick guanine-adenine base-pair sequences.
Topics: Adenine; Base Pairing; Base Sequence; Circular Dichroism; Guanine; Hydrogen Bonding; Nucleic Acid Conformation; Porphyrins | 2006 |
Ab initio base-pairing energies of uracil and 5-hydroxyuracil with standard DNA bases at the BSSE-free DFT and MP2 theory levels.
Topics: Adenine; Base Pairing; Cytosine; DNA; Guanine; Models, Molecular; Thymine; Uracil | 2006 |
Expanding the mutational spectrum in TGFBI-linked corneal dystrophies: Identification of a novel and unusual mutation (Val113Ile) in a family with granular dystrophy.
Topics: Adenine; Adult; Base Sequence; Corneal Dystrophies, Hereditary; Corneal Opacity; Corneal Stroma; Extracellular Matrix Proteins; Female; Guanine; Heterozygote; Humans; Isoleucine; Mutation, Missense; Transforming Growth Factor beta; Valine | 2006 |
Identification of the genetic defect in the original Wagner syndrome family.
Topics: Adenine; Case-Control Studies; Chondroitin Sulfate Proteoglycans; Chromosome Segregation; DNA, Recombinant; Exons; Eye Diseases; Female; Genes, Dominant; Guanine; Heterozygote; Humans; Lectins, C-Type; Male; Pedigree; Phenotype; Retinal Degeneration; RNA, Messenger; Syndrome; Versicans; Vitreous Body | 2006 |
Contribution of gene sequence variations of the hepatic cytochrome P450 3A4 enzyme to variability in individual responsiveness to clopidogrel.
Topics: Adenine; Alleles; Anticoagulants; Aspirin; Blood Platelets; Clopidogrel; Cohort Studies; Coronary Artery Disease; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Genetic Variation; Genotype; Guanine; Humans; Introns; Liver; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Polymorphism, Genetic; Ticlopidine | 2006 |
Thermodynamic and kinetic characterization of ligand binding to the purine riboswitch aptamer domain.
Topics: 2-Aminopurine; 5' Untranslated Regions; Adenine; Aptamers, Nucleotide; Guanine; Ligands; Models, Molecular; Mutation; Nucleic Acid Conformation; Purines; Pyrimidines; Regulatory Sequences, Ribonucleic Acid; RNA, Bacterial; Thermodynamics | 2006 |
The relationship between libido and testosterone levels in aging men.
Topics: Adenine; Adult; Aged; Aging; Cytosine; Follow-Up Studies; Guanine; Humans; Libido; Longitudinal Studies; Luteinizing Hormone; Male; Middle Aged; Receptors, Androgen; Repetitive Sequences, Nucleic Acid; Testosterone | 2006 |
Human enamel phenotype associated with amelogenesis imperfecta and a kallikrein-4 (g.2142G>A) proteinase mutation.
Topics: Adenine; Amelogenesis Imperfecta; Crystallization; Crystallography; Dental Enamel; Dental Enamel Proteins; Guanine; Humans; Kallikreins; Microscopy, Electron; Mutation; Phenotype; Porosity; Sequence Analysis, Protein; Tooth, Deciduous | 2006 |
DNA sequence recognition by Hoechst 33258 conjugates of hairpin pyrrole/imidazole polyamides.
Topics: Adenine; Base Pairing; Base Sequence; Bisbenzimidazole; Cytosine; DNA; Guanine; Imidazoles; Molecular Sequence Data; Nylons; Peptides; Pyrroles; Temperature; Thymine | 2006 |
Functional variation in VEGF is not associated with type 2 diabetes in a United Kingdom Caucasian population.
Topics: Adenine; Adult; Case-Control Studies; Cytosine; Diabetes Mellitus, Type 2; Female; Gene Frequency; Genetic Predisposition to Disease; Genetic Variation; Guanine; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; United Kingdom; Vascular Endothelial Growth Factor A; White People | 2006 |
Mutation analysis of the MSX1 gene exons and intron in patients with nonsyndromic cleft lip and palate.
Topics: Adenine; Cleft Lip; Cleft Palate; Cytosine; Exons; Gene Deletion; Gene Frequency; Guanine; Humans; Introns; Latvia; MSX1 Transcription Factor; Mutation; Open Reading Frames; Polymorphism, Single Nucleotide; Sequence Analysis, DNA; Thymine | 2006 |
Analysis of the effect of multiple genetic variants of cardiovascular disease risk on insulin concentration variability in healthy adults of the STANISLAS cohort. The role of FGB-455 G/A polymorphism.
Topics: Adenine; Adult; Cardiovascular Diseases; Cohort Studies; Cross-Sectional Studies; Fasting; Female; Fibrinogen; France; Gene Frequency; Genetic Predisposition to Disease; Genotype; Guanine; Homeostasis; Humans; Immunoenzyme Techniques; Insulin; Male; Metabolic Syndrome; Middle Aged; Polymorphism, Single Nucleotide; Reference Values; Risk Factors | 2007 |
[The use of nucleotide analogues in treating patients with chronic hepatitis B].
Topics: Adenine; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates | 2006 |
[Problems of and strategies in nucleotide analogues therapy for chronic hepatitis B].
Topics: Adenine; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates | 2006 |
An alternating sheared AA pair and elements of stability for a single sheared purine-purine pair flanked by sheared GA pairs in RNA.
Topics: Adenine; Base Pairing; Deinococcus; Guanine; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Nucleic Acid Heteroduplexes; RNA, Bacterial; RNA, Ribosomal; Thermodynamics | 2006 |
Maternal IVS1-401 T allele of the estrogen receptor alpha is an independent predictor of late fetal loss.
Topics: Abortion, Spontaneous; Adenine; Alleles; Case-Control Studies; Cytosine; Estrogen Receptor alpha; Factor V; Female; Gene Frequency; Genetic Predisposition to Disease; Guanine; History, 16th Century; Humans; Introns; Pregnancy; Pregnancy Trimester, Third; Thymine | 2006 |
[Hyperintense optic nerve lesion on T2-weighted MRI imaging in the acute stage of Leber's hereditary optic neuropathy: a case report].
Topics: Acute Disease; Adenine; Diagnosis, Differential; DNA, Mitochondrial; Guanine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Nucleotides; Optic Atrophy, Hereditary, Leber; Optic Nerve; Point Mutation; Vision Disorders | 2006 |
Binding of gold clusters with DNA base pairs: a density functional study of neutral and anionic GC-Aun and AT-Aun (n = 4, 8) complexes.
Topics: Adenine; Base Composition; Base Pairing; Cytosine; DNA; Gold; Guanine; Models, Chemical; Models, Molecular; Molecular Structure; Nucleic Acid Conformation; Static Electricity; Thermodynamics; Thymine | 2006 |
The MHC2TA -168A>G gene polymorphism is not associated with rheumatoid arthritis in Austrian patients.
Topics: Adenine; Aged; Arthritis, Rheumatoid; Austria; Case-Control Studies; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Guanine; Humans; Male; Middle Aged; Nuclear Proteins; Polymorphism, Genetic; Sweden; Trans-Activators; White People | 2006 |
A distinct TthMutY bifunctional glycosylase that hydrolyzes not only adenine but also thymine opposite 8-oxoguanine in the hyperthermophilic bacterium, Thermus thermophilus.
Topics: Adenine; Amino Acid Sequence; Base Pair Mismatch; Base Sequence; Binding Sites; DNA Glycosylases; DNA Primers; DNA Repair; Guanine; Molecular Sequence Data; Sequence Analysis, DNA; Sequence Homology; Thermus thermophilus; Thymine | 2006 |
Effect of Factor V Leiden and prothrombin G20210-->A mutations on thromboembolic risk in the national surgical adjuvant breast and bowel project breast cancer prevention trial.
Topics: Adenine; Adult; Aged; Antineoplastic Agents, Hormonal; Breast Neoplasms; Case-Control Studies; Factor V; Female; Guanine; Humans; Logistic Models; Matched-Pair Analysis; Middle Aged; Mutation; Odds Ratio; Polymerase Chain Reaction; Predictive Value of Tests; Prothrombin; Risk Assessment; Risk Factors; Selective Estrogen Receptor Modulators; Tamoxifen; Thromboembolism; Venous Thrombosis | 2006 |
Association of breast cancer outcome with status of p53 and MDM2 SNP309.
Topics: Adenine; Adult; Aged; Biomarkers, Tumor; Breast Neoplasms; Case-Control Studies; Female; Guanine; Haplotypes; Homozygote; Humans; Incidence; Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide; Predictive Value of Tests; Promoter Regions, Genetic; Proto-Oncogene Proteins c-mdm2; Risk Assessment; Risk Factors; Survival Analysis; Tumor Suppressor Protein p53 | 2006 |
Myeloperoxidase G-463A polymorphism and the risk of gastric cancer: a case-control study.
Topics: Adenine; Adult; Case-Control Studies; China; Female; Guanine; Humans; Incidence; Male; Middle Aged; Peroxidase; Polymorphism, Single Nucleotide; Risk Factors; Rural Population; Stomach Neoplasms; Urban Population | 2006 |
Stabilization energies of the hydrogen-bonded and stacked structures of nucleic acid base pairs in the crystal geometries of CG, AT, and AC DNA steps and in the NMR geometry of the 5'-d(GCGAAGC)-3' hairpin: Complete basis set calculations at the MP2 and C
Topics: Adenine; Algorithms; Base Pairing; Base Sequence; Cytosine; Guanine; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Thermodynamics; Thymine | 2005 |
Effects of hydrogen bonding on the acidity of adenine, guanine, and their 8-oxo derivatives.
Topics: Acids; Adenine; Guanine; Hydrogen Bonding; Hydrogen-Ion Concentration; Molecular Structure; Oxygen; Protons; Thermodynamics | 2005 |
A TDDFT study of the optical response of DNA bases, base pairs, and their tautomers in the gas phase.
Topics: Adenine; Base Composition; Base Pairing; Cytosine; DNA; Gases; Guanine; Light; Models, Molecular; Molecular Structure; Phase Transition; Quantum Theory; Spectrum Analysis; Stereoisomerism; Thymine | 2005 |
Amplified oligonucleotide sensing in microliter volumes containing copper ions by solution streaming.
Topics: Adenine; Argon; Base Sequence; Copper; DNA Probes; Guanine; Ions; Microscopy, Atomic Force; Oligonucleotides; Solutions | 2006 |
Profiles of purine biosynthesis, salvage and degradation in disks of potato (Solanum tuberosum L.) tubers.
Topics: Adenine; Deoxyribonucleosides; Guanine; Guanosine; Hypoxanthine Phosphoribosyltransferase; Inosine; Metabolic Networks and Pathways; Models, Biological; Pentosyltransferases; Plant Tubers; Purine Nucleotides; Purine-Nucleoside Phosphorylase; Purines; Ribonucleosides; Solanum tuberosum; Xanthine; Xanthines | 2006 |
Electronic structure of the nucleobases.
Topics: Adenine; Cytosine; Guanine; Spectrum Analysis; Thymine; X-Rays | 2005 |
Polarons in DNA: transition from guanine to adenine transport.
Topics: Adenine; Chemical Phenomena; Chemistry, Physical; DNA; Energy Transfer; Guanine; Thermodynamics | 2005 |
Theoretical study of cisplatin binding to DNA: the importance of initial complex stabilization.
Topics: Adenine; Antineoplastic Agents; Chemical Phenomena; Chemistry, Physical; Cisplatin; DNA; Guanine; Hydrogen Bonding; Ions; Kinetics; Ligands; Models, Chemical; Models, Molecular; Molecular Conformation; Thermodynamics | 2005 |
On the structure and desorption dynamics of DNA bases adsorbed on gold: a temperature-programmed study.
Topics: Adenine; Adsorption; Cytosine; DNA; Gold; Guanine; Molecular Structure; Spectrum Analysis; Temperature; Thymine; Vibration | 2005 |
Na+, Mg2+, and Zn2+ binding to all tautomers of adenine, cytosine, and thymine and the eight most stable keto/enol tautomers of guanine: a correlated ab initio quantum chemical study.
Topics: Adenine; Binding Sites; Cations; Cytosine; Guanine; Ketones; Magnesium; Nucleic Acid Conformation; Quantum Theory; Sodium; Stereoisomerism; Thymine; Zinc | 2006 |
Hepatitis B virus with primary resistance to adefovir.
Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Guanine; Hepatitis B Antibodies; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Mutation; Organophosphonates; Viral Load | 2006 |
Association of atrial natriuretic peptide and type a natriuretic peptide receptor gene polymorphisms with left ventricular mass in human essential hypertension.
Topics: Adenine; Adult; Alleles; Atrial Natriuretic Factor; Cytosine; Echocardiography; Female; Genetic Variation; Guanine; Guanylate Cyclase; Heterozygote; Homozygote; Humans; Hypertension; Hypertrophy, Left Ventricular; Introns; Male; Natriuretic Peptide, Brain; Phenotype; Polymorphism, Genetic; Promoter Regions, Genetic; Receptors, Atrial Natriuretic Factor; Thymine; Ventricular Remodeling | 2006 |
OPTN gene: profile of patients with glaucoma from India.
Topics: Adenine; Adult; Aged; Amino Acid Substitution; Asian People; Binding Sites; Cell Cycle Proteins; Gene Frequency; Glaucoma; Guanine; Humans; India; Intraocular Pressure; Introns; Lysine; Membrane Transport Proteins; Methionine; Middle Aged; Mutation; Transcription Factor TFIIIA; Transcription Factors | 2006 |
Nanoswitches based on DNA base pairs: why adenine-thymine is less suitable than guanine-cytosine.
Topics: Adenine; Base Composition; Base Pairing; Biophysics; Cytosine; DNA; Guanine; Hydrogen Bonding; Models, Chemical; Molecular Conformation; Nanocomposites; Nanoparticles; Nanotechnology; Thermodynamics; Thymine | 2006 |
The practical and pedagogical advantages of an ambigraphic nucleic acid notation.
Topics: Adenine; Cytosine; DNA, Complementary; GC Rich Sequence; Guanine; Nucleic Acids; Repetitive Sequences, Nucleic Acid; Sequence Analysis, DNA; Terminology as Topic; Thymine | 2006 |
Genetic polymorphisms in the MMP-1 and MMP-3 gene may contribute to chronic periodontitis in a Brazilian population.
Topics: Adenine; Adult; Alleles; Brazil; Chronic Disease; Female; Gene Frequency; Genetic Predisposition to Disease; Genetic Variation; Genotype; Guanine; Haplotypes; Humans; Male; Matrix Metalloproteinase 1; Matrix Metalloproteinase 3; Periodontal Attachment Loss; Periodontitis; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Promoter Regions, Genetic | 2006 |
The short vitamin D receptor is associated with increased risk for generalized aggressive periodontitis.
Topics: Adenine; Adult; Alveolar Bone Loss; Codon; Cytosine; Exons; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Guanine; Haplotypes; Homozygote; Humans; Introns; Male; Periodontal Attachment Loss; Periodontitis; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Receptors, Calcitriol; Risk Factors; Thymine | 2006 |
Tricyclic etheno analogs of PMEG and PMEDAP: synthesis and biological activity.
Topics: Adenine; Antiviral Agents; Cell Proliferation; Cytomegalovirus; Guanine; Herpesvirus 3, Human; Humans; Organophosphorus Compounds; Structure-Activity Relationship | 2006 |
Electrocatalytic properties of guanine, adenine, guanosine-5'-monophosphate, and ssDNA by Fe(II) bis(2,2':6',2''-terpyridine), Fe(II) tris(1,10-phenanthroline), and poly-Fe(II) tris(5-amino-1,10-phenanthroline).
Topics: Adenine; Catalysis; DNA; Electric Conductivity; Electrochemistry; Ferric Compounds; Ferrous Compounds; Guanine; Guanosine Monophosphate; Phenanthrolines; Pyridines | 2007 |
A/G heterozygote of the A-3826G polymorphism in the UCP-1 gene has higher BMI than A/A and G/G homozygote in young Japanese males.
Topics: Adenine; Adult; Alleles; Asian People; Body Composition; Body Mass Index; DNA; Genotype; Guanine; Heterozygote; Homozygote; Humans; Ion Channels; Japan; Male; Mitochondrial Proteins; Obesity; Polymorphism, Genetic; Uncoupling Protein 1 | 2006 |
Interaction energy contributions of H-bonded and stacked structures of the AT and GC DNA base pairs from the combined density functional theory and intermolecular perturbation theory approach.
Topics: Adenine; Base Pairing; Cytosine; DNA; Guanine; Hydrogen Bonding; Nucleic Acid Conformation; Quantum Theory; Thermodynamics; Thymine | 2006 |
Towards a better understanding of the unusual conformations of the alternating guanine-adenine repeat strands of DNA.
Topics: Adenine; Circular Dichroism; DNA; Ethanol; Guanine; Models, Biological; Nitrogen; Nucleic Acid Conformation; Repetitive Sequences, Nucleic Acid | 2007 |
Genetic analysis of the GRIK2 modifier effect in Huntington's disease.
Topics: 3' Untranslated Regions; Adenine; Age of Onset; Alleles; Cytosine; Exons; Genetic Variation; GluK2 Kainate Receptor; Guanine; Humans; Huntington Disease; Receptors, Kainic Acid; Trinucleotide Repeats | 2006 |
Ab initio determination of the ionization potentials of DNA and RNA nucleobases.
Topics: Adenine; Base Composition; Biophysics; Calibration; Chemistry, Physical; Cytosine; DNA; Guanine; Ions; Photochemistry; Quantum Theory; RNA; Software; Thymine; Uracil | 2006 |
Structures of nucleobases trapped within Au triangles and its effects on hydrogen bonding in base pairs of DNA.
Topics: Adenine; Base Composition; Chemistry, Physical; Cytosine; DNA; Electrochemistry; Gold; Guanine; Hydrogen Bonding; Models, Molecular; Molecular Conformation; Nucleic Acid Conformation; Oxygen; Spectrophotometry, Infrared; Thymine | 2006 |
Prothrombin A19911G polymorphism and the risk of venous thromboembolism.
Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; Case-Control Studies; Child; Factor V; Female; Genetic Predisposition to Disease; Guanine; Heterozygote; Humans; Italy; Male; Middle Aged; Odds Ratio; Polymorphism, Genetic; Prothrombin; Risk Factors; Thromboembolism; Thrombophilia; Venous Thrombosis | 2006 |
Contrasting genome-wide distribution of 8-hydroxyguanine and acrolein-modified adenine during oxidative stress-induced renal carcinogenesis.
Topics: Acrolein; Adenine; Animals; Antibodies, Monoclonal; Cell Transformation, Neoplastic; Chromosome Mapping; DNA; DNA Glycosylases; Gene Expression; Gene Library; Genes, Neoplasm; Genome; Guanine; Immunoprecipitation; Kidney; Kidney Neoplasms; Male; Mice; Mice, Knockout; Oxidation-Reduction; Oxidative Stress | 2006 |
9-{[3-fluoro-2-(hydroxymethyl)cyclopropylidene]methyl}adenines and -guanines. Synthesis and antiviral activity of all stereoisomers1.
Topics: Adenine; Adenosine Deaminase; Antiviral Agents; Cyclopropanes; Cytomegalovirus; Cytopathogenic Effect, Viral; Guanine; Hepatitis B virus; Herpesvirus 1, Human; Herpesvirus 2, Human; Herpesvirus 3, Human; Herpesvirus 4, Human; HIV-1; Humans; Purine Nucleosides; Stereoisomerism; Structure-Activity Relationship; Viral Plaque Assay | 2006 |
Pt-bridges in various single-strand and double-helix DNA sequences. DFT and MP2 study of the cisplatin coordination with guanine, adenine, and cytosine.
Topics: Adenine; Cisplatin; Cytosine; DNA, Single-Stranded; Guanine; Models, Molecular; Nucleic Acid Heteroduplexes; Platinum | 2007 |
Regulation of purine nucleotide biosynthesis: in yeast and beyond.
Topics: Adenine; Bacillus subtilis; Escherichia coli; Guanine; Hypoxanthine; Lactococcus lactis; Models, Biological; Purine Nucleotides; Saccharomyces cerevisiae; Salmonella typhimurium; Signal Transduction; Transcriptional Activation | 2006 |
The association of prothrombin A19911G polymorphism with plasma prothrombin activity and venous thrombosis: results of the MEGA study, a large population-based case-control study.
Topics: Adenine; Adult; Aged; Case-Control Studies; Factor V; Female; Gene Frequency; Genetic Predisposition to Disease; Guanine; Heterozygote; Humans; Male; Middle Aged; Netherlands; Odds Ratio; Polymorphism, Genetic; Population Surveillance; Prothrombin; Risk Factors; Venous Thrombosis | 2006 |
Tuning the gas phase redox properties of copper(II) ternary complexes of terpyridines to control the formation of nucleobase radical cations.
Topics: Adenine; Cations; Copper; Crystallography, X-Ray; Cytosine; Free Radicals; Gases; Guanine; Molecular Structure; Organometallic Compounds; Oxidation-Reduction; Purines; Pyridines; Pyrimidines; Spectrometry, Mass, Electrospray Ionization; Thymine | 2006 |
Type and location of venous thromboembolism in patients with factor V Leiden or prothrombin G20210A and in those with no thrombophilia.
Topics: Adenine; Adolescent; Adult; Age Distribution; Age Factors; Aged; Aging; Child; Cohort Studies; Factor V; Genetic Predisposition to Disease; Guanine; Humans; Incidence; Male; Middle Aged; Polymorphism, Single Nucleotide; Prevalence; Prothrombin; Pulmonary Embolism; Retrospective Studies; Risk Factors; Severity of Illness Index; Thrombophilia; Venous Thrombosis | 2007 |
Modified pyrimidines specifically bind the purine riboswitch.
Topics: Adenine; Base Pairing; Binding Sites; Crystallography, X-Ray; Guanine; Nucleic Acid Conformation; Purines; Pyrimidines; Regulatory Sequences, Ribonucleic Acid; Ribosomes | 2006 |
Local aromaticity in natural nucleobases and their size-expanded benzo-fused derivatives.
Topics: Adenine; Benzene; Cytosine; Guanine; Hydrogen Bonding; Molecular Structure; Nucleic Acids; Polycyclic Aromatic Hydrocarbons; Thymine | 2006 |
Cytogenetic damage induced by acrylamide and glycidamide in mammalian cells: correlation with specific glycidamide-DNA adducts.
Topics: Acrylamide; Adenine; Animals; Cell Line; Chromosome Aberrations; Cricetinae; Cricetulus; DNA Adducts; Dose-Response Relationship, Drug; Epoxy Compounds; Guanine; Molecular Structure; Mutagens; Sister Chromatid Exchange | 2007 |
The nature of the adsorption of nucleobases on the gold [111] surface.
Topics: Adenine; Adsorption; Algorithms; Computer Simulation; Cytosine; DNA; Gold; Guanine; Hydrogen Bonding; Nucleic Acid Conformation; Surface Properties; Thymine | 2006 |
Effect of water drag on diffusion of drifting polarons in DNA.
Topics: Adenine; Algorithms; Base Pairing; Diffusion; DNA; Guanine; Models, Theoretical; Nucleic Acid Conformation; Solutions; Water | 2006 |
KLF6 IVS1 -27G>A variant and the risk of prostate cancer in Finland.
Topics: Adenine; Finland; Genetic Variation; Genotype; Germ-Line Mutation; Guanine; Humans; Kruppel-Like Factor 6; Kruppel-Like Transcription Factors; Male; Polymorphism, Single Nucleotide; Prostatic Hyperplasia; Prostatic Neoplasms; Proto-Oncogene Proteins; Risk Factors; Tumor Suppressor Proteins | 2007 |
Differential physiological and developmental expression of the UapA and AzgA purine transporters in Aspergillus nidulans.
Topics: Adenine; Aspergillus nidulans; Biological Transport; Carrier Proteins; Cell Membrane; Culture Media; Down-Regulation; Fungal Proteins; Guanine; Hyphae; Hypoxanthine; Immunoblotting; Membrane Transport Proteins; Purines; Quaternary Ammonium Compounds | 2007 |
Association of genetic polymorphisms of ACADSB and COMT with human hypertension.
Topics: Acyl-CoA Dehydrogenases; Adenine; Aged; Asian People; Blood Pressure; Cohort Studies; Cytosine; DNA-Binding Proteins; Female; Gene Frequency; Genetic Predisposition to Disease; Guanine; Humans; Hypertension; Ikaros Transcription Factor; Japan; Linkage Disequilibrium; Logistic Models; Male; Methyltransferases; Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide; Pyridoxaminephosphate Oxidase; Risk Factors; Sex Characteristics; Sex Distribution; Sex Factors; Transcription Factors | 2007 |
Flat-type colorectal advanced adenomas (laterally spreading tumors) have different genetic and epigenetic alterations from protruded-type advanced adenomas.
Topics: Adaptor Proteins, Signal Transducing; Adenine; Adenoma; Aged; beta Catenin; Carrier Proteins; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p16; DNA Methylation; DNA Modification Methylases; DNA Mutational Analysis; DNA Repair Enzymes; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Guanine; Humans; Male; Middle Aged; Mutation; MutL Protein Homolog 1; Neoplasm Invasiveness; Nuclear Proteins; Polymerase Chain Reaction; Proto-Oncogene Proteins B-raf; ras Proteins; Tumor Suppressor Protein p14ARF; Tumor Suppressor Proteins | 2007 |
Electronic structure of DNA nucleobases and their dinucleotides explored by soft X-ray spectroscopy.
Topics: Adenine; Cytosine; DNA; Electrons; Guanine; Purine Nucleotides; Pyrimidine Nucleotides; Spectrometry, X-Ray Emission; Spectrum Analysis; Thymine; X-Rays | 2006 |
Octaplex formation of d(GCGAAAGC) with the double A-quartet.
Topics: Adenine; Base Sequence; DNA; G-Quadruplexes; Guanine; Minisatellite Repeats; Models, Molecular | 2005 |
New designs for DNA bases: expanded DNAs and oligofluorosides.
Topics: Adenine; Base Pairing; Cytosine; DNA; Fluorescent Dyes; Guanine; Oligodeoxyribonucleotides; Oligonucleotide Probes; Thymine | 2006 |
NMR studies of the effect of GA-AG base pairs to the active conformation of hammerhead ribozyme.
Topics: Adenine; Base Pairing; Guanine; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; RNA, Catalytic | 2006 |
Inhibition of DNA replication by a d(CAG) repeat binding ligand.
Topics: Adenine; DNA; DNA Replication; DNA-Directed DNA Polymerase; Guanine; Hydrogen Bonding; Ligands; Naphthyridines; Nucleic Acid Conformation; Quinolones; Trinucleotide Repeat Expansion | 2006 |
Purine analog substitution of the HIV-1 polypurine tract primer defines regions controlling initiation of plus-strand DNA synthesis.
Topics: Adenine; Base Sequence; DNA Replication; DNA, Viral; Guanine; HIV-1; Models, Genetic; Mutation; Purine Nucleosides; Regulatory Sequences, Ribonucleic Acid; Ribonuclease H; RNA; RNA, Viral; Uracil | 2007 |
Lack of association between EGF 61A>G polymorphism and plasma EGF concentration in the STANISLAS family study.
Topics: Adenine; Epidermal Growth Factor; Guanine; Humans; Melanoma; Osmolar Concentration; Polymorphism, Genetic; Prognosis; Skin Neoplasms | 2007 |
Erythropoietin delays disease onset in an amyotrophic lateral sclerosis model.
Topics: Adenine; Amyotrophic Lateral Sclerosis; Animals; Disease Progression; Erythropoietin; Female; Guanine; Humans; Injections, Intraperitoneal; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Motor Neurons; Mutation; Neuroprotective Agents; Recombinant Proteins; Sex Factors; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1; Time Factors | 2007 |
Mechanism of 3-deazaguanine transport in the rat heart.
Topics: Adenine; Adenosine; Animals; Dinitrophenols; Female; Guanine; In Vitro Techniques; Male; Myocardium; Nucleoside Transport Proteins; Radioisotope Dilution Technique; Rats; Sodium; Thymidine; Thymine; Tritium | 2006 |
A potential prebiotic route to adenine from hypoxanthine.
Topics: Adenine; Glycine; Guanine; Hypoxanthine; Molecular Structure; Urea; Xanthine | 2005 |
Interaction of low-energy electrons with the purine bases, nucleosides, and nucleotides of DNA.
Topics: Adenine; Computer Simulation; DNA; DNA Damage; Electrons; Guanine; Models, Chemical; Models, Molecular; Nucleosides; Nucleotides; Purines | 2006 |
Prevalence of hepatitis B virus genotype D in precore mutants among chronic liver disease patients from New Delhi, India.
Topics: Adenine; Adult; DNA Mutational Analysis; DNA, Viral; Female; Genotype; Guanine; Hepatitis B Core Antigens; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; India; Ligase Chain Reaction; Male; Point Mutation; Prevalence; Prognosis | 2007 |
The +61 A-G polymorphism of the epidermal growth factor gene is not associated with occurrence of non-melanocytic skin tumors in transplant recipients.
Topics: Adenine; Age Factors; Aged; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Epidermal Growth Factor; Female; Follow-Up Studies; Gene Frequency; Genotype; Guanine; Heart Transplantation; Humans; Italy; Kidney Transplantation; Liver Transplantation; Male; Middle Aged; Organ Transplantation; Polymorphism, Single Nucleotide; Prognosis; Proportional Hazards Models; Risk Assessment; Risk Factors; Skin Neoplasms; Time Factors | 2007 |
Formation of depurinating N3adenine and N7guanine adducts after reaction of 1,2-naphthoquinone or enzyme-activated 1,2-dihydroxynaphthalene with DNA. Implications for the mechanism of tumor initiation by naphthalene.
Topics: Adenine; Carcinogens; DNA Adducts; Guanine; Kinetics; Molecular Structure; Naphthalenes; Naphthols; Naphthoquinones; Neoplasms | 2007 |
Formation of depurinating N3Adenine and N7Guanine adducts by MCF-10F cells cultured in the presence of 4-hydroxyestradiol.
Topics: Adenine; Breast; Cells, Cultured; Chromatography, High Pressure Liquid; DNA; DNA Adducts; DNA Damage; Estradiol; Estrogens, Catechol; Guanine; Humans; Molecular Structure; Solid Phase Extraction; Tandem Mass Spectrometry | 2007 |
Does the A.T or G.C base-pair possess enhanced stability? Quantifying the effects of CH...O interactions and secondary interactions on base-pair stability using a phenomenological analysis and ab initio calculations.
Topics: Adenine; Base Composition; Base Pairing; Cytosine; DNA; Guanine; Hydrogen Bonding; Mathematical Computing; Models, Chemical; Thermodynamics; Thymine | 2007 |
Association of A313 G polymorphism (GSTP1*B) in the glutathione-S-transferase P1 gene with sporadic Parkinson's disease.
Topics: Adenine; Aged; Aged, 80 and over; Alleles; Cytochrome P-450 CYP2D6; Gene Deletion; Genetic Predisposition to Disease; Genetic Variation; Genotype; Glutathione S-Transferase pi; Glutathione Transferase; Guanine; Heterozygote; Homozygote; Humans; Middle Aged; Parkinson Disease; Phenotype; Polymorphism, Genetic | 2007 |
Voltammetric quantification of adenine and guanine at C60 modified glassy carbon electrodes.
Topics: Adenine; Biosensing Techniques; Crystallization; DNA; Electrochemistry; Fullerenes; Guanine; Macromolecular Substances; Materials Testing; Microelectrodes; Molecular Conformation; Nanostructures; Nanotechnology; Particle Size; Surface Properties | 2006 |
Rescue therapy for lamivudine-resistant chronic hepatitis B: when and how?
Topics: Adenine; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Organophosphonates; Salvage Therapy | 2007 |
Electrophilicity-based charge transfer descriptor.
Topics: Adenine; Base Pairing; Cytosine; DNA; Electrochemistry; Guanine; Models, Molecular; Molecular Conformation; Polychlorinated Biphenyls; Quantitative Structure-Activity Relationship; Thymine | 2007 |
Highly selective recognition of cytosine over uracil and adenine by a guanine analogue, 2-N-acetyl-3-deazaguanine, in 2'-O-methyl-RNA/RNA and DNA duplexes.
Topics: Adenine; Base Pairing; Base Sequence; Cytosine; DNA; Guanine; Methylation; Models, Chemical; RNA, Double-Stranded; Uracil | 2007 |
Factors determining the deriving force of DNA formation: geometrical differences of base pairs, dehydration of bases, and the arginine assisting.
Topics: Adenine; Arginine; Base Pair Mismatch; Base Pairing; Binding Sites; Cytosine; Dehydration; Deoxyguanine Nucleotides; Deoxyribose; DNA; Guanine; Hydrogen Bonding; Models, Molecular; Oxygen; RNA-Directed DNA Polymerase; Templates, Genetic; Thymine; Water | 2007 |
Transition-transversion bias is not universal: a counter example from grasshopper pseudogenes.
Topics: Adenine; Animals; Cytosine; DNA, Ribosomal; Drosophila melanogaster; Grasshoppers; Guanine; Molecular Sequence Data; Mutagenesis; Mutation; Pseudogenes; Thymine | 2007 |
Early vulnerability to ischemia/reperfusion injury in motor terminals innervating fast muscles of SOD1-G93A mice.
Topics: Adenine; Animals; Denervation; Genetic Predisposition to Disease; Guanine; Hindlimb; Humans; Male; Mice; Mice, Transgenic; Motor Endplate; Muscle Fibers, Fast-Twitch; Muscle Fibers, Slow-Twitch; Muscle, Skeletal; Mutation; Nerve Endings; Nerve Regeneration; Reperfusion Injury; Superoxide Dismutase; Superoxide Dismutase-1 | 2007 |
Characterization of the role of para-aminobenzoic acid biosynthesis in folate production by Lactococcus lactis.
Topics: 4-Aminobenzoic Acid; Adenine; Folic Acid; Gene Deletion; Genes, Bacterial; Guanine; Inosine; Lactococcus lactis; Metabolic Networks and Pathways; Models, Biological; Xanthine | 2007 |
Cyclin D1 guanine/adenine 870 polymorphism with altered protein expression is associated with genomic instability and aggressive clinical biology of esophageal adenocarcinoma.
Topics: Adenine; Adenocarcinoma; Adult; Aged; Biomarkers, Tumor; Biopsy, Needle; Cohort Studies; Cyclin D1; Disease Progression; Esophageal Neoplasms; Esophagectomy; Esophagoscopy; Female; Gene Expression Regulation, Neoplastic; Genomic Instability; Guanine; Humans; Immunohistochemistry; Male; Middle Aged; Polymorphism, Genetic; Probability; Proportional Hazards Models; Retrospective Studies; Risk Assessment; Sensitivity and Specificity; Survival Analysis | 2007 |
Interguanine hydrogen-bonding patterns in adducts with water and Zn-purine complexes (purine is 9-methyladenine and 9-methylguanine). Unexpected preference of Zn(II) for adenine-N7 over guanine-N7.
Topics: Adenine; Crystallography, X-Ray; Guanine; Hydrogen Bonding; Models, Molecular; Molecular Structure; Stereoisomerism; Water; Zinc | 2007 |
Antiviral therapy for pre- and post-liver transplantation patients with hepatitis B.
Topics: Adenine; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B; Hepatitis B virus; Humans; Kidney Diseases; Lamivudine; Liver Transplantation; Organophosphonates; Secondary Prevention; Tenofovir | 2007 |
Shorter CAG repeat length in the AR gene is associated with poor outcome in head and neck cancer.
Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; Alleles; Case-Control Studies; Cytosine; Disease-Free Survival; Female; Follow-Up Studies; Guanine; Head and Neck Neoplasms; Humans; Loss of Heterozygosity; Male; Microsatellite Instability; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Polymorphism, Genetic; Prognosis; Receptors, Androgen; Sex Factors; Survival Rate; Trinucleotide Repeats | 2007 |
Xanthurenic aciduria due to a mutation in KYNU encoding kynureninase.
Topics: Adenine; Alanine; Amino Acid Metabolism, Inborn Errors; Amino Acid Substitution; Child; DNA Mutational Analysis; Genotype; Guanine; Homozygote; Humans; Hydrolases; Male; Mutation; Pedigree; Threonine; Xanthurenates | 2007 |
Methylenetetrahydrofolate reductase 677C>T and methionine synthase 2756A>G mutations: no impact on survival, cognitive functioning, or cognitive decline in nonagenarians.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenine; Aged, 80 and over; Cognition; Cognition Disorders; Cohort Studies; Cytosine; Denmark; Female; Genetic Markers; Genotype; Geriatric Assessment; Guanine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Polymorphism, Genetic; Survival Rate; Thymine | 2007 |
Very low penetrance of hearing loss in seven Han Chinese pedigrees carrying the deafness-associated 12S rRNA A1555G mutation.
Topics: Adenine; Adolescent; Adult; Aminoglycosides; Asian People; Child; China; Connexin 26; Connexins; Deafness; DNA Mutational Analysis; DNA, Mitochondrial; Female; Genome, Human; Guanine; Hearing Loss, Bilateral; Humans; Male; Mutation; Pedigree; Penetrance; RNA, Ribosomal | 2007 |
Association of the Asn306Ser variant of the SP4 transcription factor and an intronic variant in the beta-subunit of transducin with digenic disease.
Topics: Adenine; Asparagine; Blindness; Cohort Studies; Exons; Genetic Variation; GTP-Binding Protein beta Subunits; Guanine; Hispanic or Latino; Humans; Introns; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Retinal Degeneration; Serine; Sp4 Transcription Factor | 2007 |
RNA polymerase II bypasses 8-oxoguanine in the presence of transcription elongation factor TFIIS.
Topics: Adenine; Base Sequence; DNA Damage; DNA Repair; Guanine; HeLa Cells; Humans; Models, Chemical; Models, Genetic; Molecular Sequence Data; Oxygen; RNA Polymerase II; Thymine; Transcription, Genetic; Transcriptional Elongation Factors | 2007 |
Estimation on the individual hydrogen-bond strength in molecules with multiple hydrogen bonds.
Topics: Adenine; Base Pairing; Chemistry, Physical; Cytosine; Dimerization; Formamides; Guanine; Hydrogen; Hydrogen Bonding; Models, Chemical; Models, Molecular; Molecular Conformation; Molecular Structure; Thymine | 2007 |
Structure of the intramolecular human telomeric G-quadruplex in potassium solution: a novel adenine triple formation.
Topics: Adenine; DNA; G-Quadruplexes; Guanine; Humans; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Potassium; Solutions; Telomere | 2007 |
Bifunctional binding of cisplatin to DNA: why does cisplatin form 1,2-intrastrand cross-links with ag but not with GA?
Topics: Adenine; Antineoplastic Agents; Base Sequence; Cisplatin; Computer Simulation; DNA; DNA Adducts; Guanine; Nucleic Acid Conformation; Thermodynamics | 2007 |
Stacking effects on local structure in RNA: changes in the structure of tandem GA pairs when flanking GC pairs are replaced by isoG-isoC pairs.
Topics: Adenine; Base Pairing; Cytidine; Guanine; Hydrogen Bonding; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; RNA; Thermodynamics | 2007 |
MTHFD 1958G>A and MTR 2756A>G polymorphisms are associated with bipolar disorder and schizophrenia.
Topics: Adenine; Bipolar Disorder; Chromosomes, Human, Pair 14; Chromosomes, Human, Pair 4; Demography; Female; Gene Frequency; Guanine; Humans; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Polymorphism, Single Nucleotide; Reference Values; Schizophrenia; White People | 2007 |
Vacuum-ultraviolet photoionization studies of the microhydration of DNA bases (guanine, cytosine, adenine, and thymine).
Topics: Adenine; Cytosine; DNA; Guanine; Microchemistry; Molecular Structure; Photochemistry; Thymine; Ultraviolet Rays; Vacuum; Volatilization; Water | 2007 |
Somatic mutations of the von Hippel-Lindau disease gene in renal carcinomas occurring in patients with long-term dialysis.
Topics: Adenine; Aged; Base Sequence; Carcinoma; Carcinoma, Renal Cell; Gene Deletion; Guanine; Humans; Kidney Failure, Chronic; Kidney Neoplasms; Middle Aged; Mutation; Renal Dialysis; Time Factors; Von Hippel-Lindau Tumor Suppressor Protein | 2007 |
TNFalpha-308G/A polymorphism as a risk factor for HPV associated cervical cancer in Indian population.
Topics: Adenine; Base Sequence; Case-Control Studies; DNA Mutational Analysis; Female; Genetic Predisposition to Disease; Genotype; Guanine; Human papillomavirus 16; Humans; India; Middle Aged; Molecular Sequence Data; Polymorphism, Single Nucleotide; Precancerous Conditions; Prevalence; Promoter Regions, Genetic; Tumor Necrosis Factor-alpha; Uterine Cervical Neoplasms; White People | 2007 |
Fluoroanalogues of anti-cytomegalovirus agent cyclopropavir: synthesis and antiviral activity of (E)- and (Z)-9-{[2,2-bis(hydroxymethyl)-3-fluorocyclopropylidene]methyl}-adenines and guanines.
Topics: Adenine; Antiviral Agents; Bromine; Chemistry, Pharmaceutical; Cyclopropanes; Cytomegalovirus; Cytomegalovirus Infections; Drug Design; Guanine; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Models, Chemical; Nucleic Acids; Nucleosides; Ultraviolet Rays | 2007 |
Qualitative and quantitative analyses of nucleosides and nucleobases in Ganoderma spp. by HPLC-DAD-MS.
Topics: Adenine; Chromatography, High Pressure Liquid; Fruiting Bodies, Fungal; Ganoderma; Guanine; Hypoxanthine; Mass Spectrometry; Molecular Structure; Nucleosides; Plant Extracts; Reference Standards; Reproducibility of Results; Species Specificity; Technology, Pharmaceutical; Thymine; Uracil | 2007 |
Angiotensin-converting enzyme gene 2350 G/A polymorphism is associated with left ventricular hypertrophy but not essential hypertension.
Topics: Adenine; Adult; Asian People; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Guanine; Humans; Hypertension; Hypertrophy, Left Ventricular; Logistic Models; Male; Middle Aged; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Risk | 2007 |
Tip-enhanced Raman spectra of picomole quantities of DNA nucleobases at Au(111).
Topics: Adenine; Cytosine; DNA; Gold; Guanine; Spectrum Analysis, Raman; Thymine | 2007 |
Genetic variations of the ABC transporter gene ABCC3 in a Japanese population.
Topics: Adenine; Asian People; Cytosine; DNA Mutational Analysis; Exons; Gene Frequency; Genotype; Guanine; Heterozygote; Humans; Introns; Japan; Linkage Disequilibrium; Multidrug Resistance-Associated Proteins; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Thymine | 2007 |
Association of CD14, IL1B, IL6, IL10 and TNFA functional gene polymorphisms with symptomatic dental abscesses.
Topics: Abscess; Adenine; Adult; Age Factors; Case-Control Studies; Chromosome Mapping; Cross-Sectional Studies; Cytosine; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Guanine; Humans; Interleukin-10; Interleukin-1beta; Interleukin-6; Lipopolysaccharide Receptors; Male; Periapical Periodontitis; Polymorphism, Genetic; Thymine; Tooth Diseases; Tumor Necrosis Factor-alpha | 2007 |
An unusual mode of DNA duplex association: Watson-Crick interaction of all-purine deoxyribonucleic acids.
Topics: Adenine; Base Pairing; Benzothiazoles; Circular Dichroism; Diamines; DNA; Electrophoresis, Polyacrylamide Gel; Guanine; Hypoxanthine; Oligodeoxyribonucleotides; Organic Chemicals; Purines; Quinolines; Ribonucleosides; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Thermodynamics | 2007 |
Efficient syntheses of C(8)-aryl adducts of adenine and guanine formed by reaction of radical cation metabolites of carcinogenic polycyclic aromatic hydrocarbons with DNA.
Topics: Adenine; Benzo(a)pyrene; Boronic Acids; Carcinogens; Cations; DNA; Free Radicals; Guanine; Molecular Structure; Polycyclic Aromatic Hydrocarbons | 2007 |
Quantum-chemical investigation of the structures and electronic spectra of the nucleic acid bases at the coupled cluster CC2 level.
Topics: Adenine; Algorithms; Carbon; Cytosine; Electrons; Guanine; Hydrogen; Nitrogen; Nucleic Acids; Quantum Theory; Spectrophotometry; Thermodynamics; Thymine; Uracil | 2007 |
A novel mutation of transferrin receptor 2 in a Taiwanese woman with type 3 hemochromatosis.
Topics: Adenine; Asian People; Base Sequence; Diabetes Mellitus; Female; Guanine; Hemochromatosis; Hemosiderin; Humans; Iron; Liver; Magnetic Resonance Imaging; Middle Aged; Pituitary Gland; Point Mutation; Receptors, Transferrin; Taiwan | 2007 |
A MELAS-associated ND1 mutation causing leber hereditary optic neuropathy and spastic dystonia.
Topics: Adenine; Adult; DNA, Mitochondrial; Dystonia; Female; Guanine; Humans; MELAS Syndrome; Muscle Spasticity; Mutation; NADH Dehydrogenase; Oligonucleotide Array Sequence Analysis; Optic Atrophy, Hereditary, Leber | 2007 |
Another mutation in cysteine 131 in protein kinase C gamma as a cause of spinocerebellar ataxia type 14.
Topics: Adenine; Amino Acid Substitution; Cysteine; Guanine; Humans; Magnetic Resonance Imaging; Male; Mutation, Missense; Protein Kinase C; Spinocerebellar Ataxias; Tyrosine | 2007 |
Photoreaction at 5'-(G/C)AA(Br)UT-3' sequence in duplex DNA: efficient generation of uracil-5-yl radical by charge transfer.
Topics: Adenine; Base Sequence; DNA; Guanine; Light; Models, Molecular; Photochemistry; Purines; Uracil | 2007 |
A 2'-methyl or 2'-methylene group at G+1 in precursor tRNA interferes with Mg2+ binding at the enzyme-substrate interface in E-S complexes of E. coli RNase P.
Topics: Adenine; Base Sequence; Cations, Divalent; Escherichia coli; Guanine; Magnesium; Methane; Methylation; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Protein Binding; Protein Structure, Tertiary; Ribonuclease P; RNA Interference; RNA Precursors; RNA, Transfer; Substrate Specificity | 2007 |
Chlorido-, aqua-, 9-ethylguanine- and 9-ethyladenine-adducts of cytotoxic ruthenium arene complexes containing O,O-chelating ligands.
Topics: Adenine; Chelating Agents; Crystallography, X-Ray; Guanine; Ligands; Models, Molecular; Molecular Structure; Organometallic Compounds; Ruthenium | 2007 |
Epidermal growth factor receptor and human epidermal growth factor receptor 2 gene polymorphisms in endometrial cancer in a Japanese population.
Topics: Adenine; Adult; Asian People; Endometrial Neoplasms; ErbB Receptors; Female; Genes, erbB-2; Guanine; Humans; Japan; Middle Aged; Neoplasm Staging; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Receptor, ErbB-2; Reference Values | 2007 |
MTR 2756 A > G polymorphism is associated with the risk of systemic lupus erythematosus in the Polish population.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenine; Adult; Gene Frequency; Genetic Predisposition to Disease; Genotype; Guanine; Heterozygote; Humans; Lupus Erythematosus, Systemic; Middle Aged; Poland; Polymorphism, Genetic; White People | 2007 |
Association of the HTRA1 -625G>A promoter gene polymorphism with exudative age-related macular degeneration in a Central European population.
Topics: Adenine; Aged; Aged, 80 and over; Complement Factor H; Europe; Female; Genetic Predisposition to Disease; Genotype; Guanine; High-Temperature Requirement A Serine Peptidase 1; Humans; Macular Degeneration; Male; Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Serine Endopeptidases; White People | 2007 |
ApolipoproteinA1-75 G/A (M1-) polymorphism and lipoprotein(a); anti- vs. pro-Atherogenic properties.
Topics: Adenine; Apolipoprotein A-I; Atherosclerosis; Gene Frequency; Genetic Carrier Screening; Genetic Predisposition to Disease; Genotype; Guanine; Homozygote; Humans; Lipoprotein(a); Polymorphism, Genetic; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Risk Factors; Triglycerides | 2007 |
Investigation of functional gene polymorphisms interleukin-1beta, interleukin-6, interleukin-10 and tumor necrosis factor in individuals with oral lichen planus.
Topics: Adenine; Adult; Aged; Case-Control Studies; Cytosine; Female; Gene Frequency; Genotype; Guanine; Homozygote; Humans; Interleukin-10; Interleukin-1beta; Interleukin-6; Lichen Planus, Oral; Male; Middle Aged; Polymorphism, Genetic; Risk Factors; Thymine; Tumor Necrosis Factor-alpha | 2007 |
A computational study on DNA bases interactions with dinuclear tetraacetato-diaqua-dirhodium(II,II) complex.
Topics: Acetates; Adenine; Computer Simulation; DNA Adducts; Guanine; Models, Molecular; Organometallic Compounds; Rhodium; Thermodynamics | 2008 |
Increased achondroplasia mutation frequency with advanced age and evidence for G1138A mosaicism in human testis biopsies.
Topics: Achondroplasia; Adenine; Adult; Aged; Biopsy; DNA; Gene Frequency; Guanine; Humans; Male; Middle Aged; Mosaicism; Mutation; Polymorphism, Single Nucleotide; Reference Values; Reproducibility of Results; Restriction Mapping; RNA; Testis | 2008 |
Density functional theory-symmetry adapted perturbation treatment energy decomposition of nucleic acid base pairs taken from DNA crystal geometry.
Topics: Adenine; Base Composition; Base Pairing; Crystallography, X-Ray; Cytosine; DNA; Guanine; Hydrogen Bonding; Nucleic Acid Conformation; Static Electricity; Thermodynamics; Thymine | 2007 |
Chronic hepatitis B: a wider range of therapeutic options.
Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Guanine; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Treatment Outcome | 2007 |
A novel mutation of COL4A3 presents a different contribution to Alport syndrome and thin basement membrane nephropathy.
Topics: Adenine; Adult; Aged; Asian People; Aspartic Acid; Autoantigens; Base Sequence; Collagen Type IV; Consanguinity; DNA Mutational Analysis; Female; Genes, Recessive; Glomerular Basement Membrane; Glycine; Guanine; Heterozygote; Homozygote; Humans; Kidney Diseases; Male; Microscopy, Electron; Middle Aged; Mutation, Missense; Nephritis, Hereditary; Pedigree; Polymorphism, Genetic | 2007 |
Prediction of the 3-D structure of rat MrgA G protein-coupled receptor and identification of its binding site.
Topics: Adenine; Amino Acid Sequence; Animals; Binding Sites; Computer Simulation; Guanine; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Molecular Structure; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Rats; Receptors, G-Protein-Coupled; Sequence Homology, Amino Acid; Structure-Activity Relationship | 2007 |
On the bonding of first-row transition metal cations to guanine and adenine nucleobases.
Topics: Adenine; Cations; Chemistry, Physical; Copper; Electronics; Electrons; Guanine; Ions; Mass Spectrometry; Metals; Models, Chemical; Models, Molecular; Models, Theoretical; Molecular Conformation; Static Electricity | 2007 |
The 212A variant of the APJ receptor gene for the endogenous inotrope apelin is associated with slower heart failure progression in idiopathic dilated cardiomyopathy.
Topics: Adenine; Adult; Alleles; Apelin; Apelin Receptors; Cardiomyopathy, Dilated; Cytosine; Disease Progression; DNA Mutational Analysis; Female; Follow-Up Studies; Gene Dosage; Genetic Variation; Genotype; Guanine; Haplotypes; Homozygote; Humans; Intercellular Signaling Peptides and Proteins; Linkage Disequilibrium; Male; Middle Aged; Myocardial Contraction; Polymorphism, Genetic; Prognosis; Prospective Studies; Receptors, G-Protein-Coupled | 2007 |
Redetection of HBV lamivudine-resistant mutations in a patient under entecavir therapy, who had been treated sequentially with nucleos(t)ide analogues.
Topics: Adenine; Adult; Antiviral Agents; Drug Administration Schedule; Drug Resistance, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Mutation; Organophosphonates; Reverse Transcriptase Inhibitors | 2007 |
Polymorphism -238 G/A of tumor necrosis factor alpha gene promoter is a genetic risk factor for ischemic cerebrovascular disease.
Topics: Adenine; Adult; Aged; Aged, 80 and over; Cerebrovascular Disorders; Female; Genotype; Guanine; Humans; Ischemia; Male; Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Reference Values; Risk Factors; Tumor Necrosis Factor-alpha | 2007 |
[New German and American guidelines for therapy of hepatitis B. Discrepancies and similarities].
Topics: Adenine; Alanine Transaminase; Antiviral Agents; Biopsy; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Germany; Guanine; Hepatitis B; Humans; Lamivudine; Liver; Liver Cirrhosis; Nucleosides; Organophosphonates; Practice Guidelines as Topic; Pyrimidinones; Telbivudine; Thymidine; United States | 2007 |
Electrochemical and spectroscopic characterization of the interaction between DNA and Cu(II)-naringin complex.
Topics: Adenine; Biosensing Techniques; Circular Dichroism; Copper; DNA; Electrochemistry; Flavanones; Guanine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Oxidation-Reduction; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Tandem Mass Spectrometry; Temperature; Water | 2007 |
HCCS loss-of-function missense mutation in a female with bilateral microphthalmia and sclerocornea: a novel gene for severe ocular malformations?
Topics: Abnormalities, Multiple; Adenine; Amino Acid Substitution; Animals; CHO Cells; Chromosomes, Human, X; Cohort Studies; Cornea; Cricetinae; Cricetulus; Eye Abnormalities; Female; Glutamic Acid; Guanine; Heterozygote; Humans; Lyases; Lysine; Microphthalmos; Mutation, Missense; Point Mutation; Saccharomyces cerevisiae; Severity of Illness Index; Transfection; X Chromosome Inactivation | 2007 |
Two novel PAX6 mutations identified in northeastern Chinese patients with aniridia.
Topics: Adenine; Adolescent; Adult; Aniridia; Asian People; Base Sequence; Child; Eye Proteins; Female; Gene Deletion; Guanine; Heterozygote; Homeodomain Proteins; Humans; Male; Mutation; Paired Box Transcription Factors; PAX6 Transcription Factor; Pedigree; Polymorphism, Single-Stranded Conformational; Repressor Proteins | 2007 |
An unusual cause of cerebral venous sinus thrombosis: prothrombin G20210A gene mutation.
Topics: Adenine; Anticoagulants; Contraceptives, Oral, Hormonal; Female; Genetic Carrier Screening; Guanine; Heparin; Humans; Middle Aged; Mutation; Prothrombin; Risk Factors; Sagittal Sinus Thrombosis; Sinus Thrombosis, Intracranial; Thrombophilia | 2007 |
Guanine riboswitch variants from Mesoplasma florum selectively recognize 2'-deoxyguanosine.
Topics: Adenine; Aptamers, Nucleotide; Base Sequence; Deoxyguanosine; Entomoplasmataceae; Genetic Variation; Guanine; Kinetics; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Point Mutation; RNA, Bacterial; Sequence Homology, Nucleic Acid | 2007 |
[Recent therapies for hepatitis B (discussion)].
Topics: Adenine; Antiviral Agents; Genotype; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferons; Lamivudine; Organophosphonates | 2007 |
A polymorphism in CD14 modifies the effect of farm milk consumption on allergic diseases and CD14 gene expression.
Topics: Adenine; Alleles; Animals; Child; Cross-Sectional Studies; Dairying; Female; Food Hypersensitivity; Gene Expression Regulation; Genotype; Guanine; Humans; Immunity, Innate; Infant; Lipopolysaccharide Receptors; Male; Milk; Polymorphism, Single Nucleotide | 2007 |
Ammonia elimination from protonated nucleobases and related synthetic substrates.
Topics: Adenine; Ammonia; Cytosine; Guanine; Protons; Spectrometry, Mass, Electrospray Ionization | 2007 |
Development and application of novel constructs to score C:G-to-T:A transitions and homologous recombination in Arabidopsis.
Topics: Adenine; Arabidopsis; Cytosine; DNA Mutational Analysis; Escherichia coli; Glucuronidase; Guanine; Molecular Sequence Data; Mutagenesis; Mutation, Missense; Plants, Genetically Modified; Recombination, Genetic; Sequence Homology, Nucleic Acid; Thymidine | 2008 |
Successful treatment of an entecavir-resistant hepatitis B virus variant.
Topics: Adenine; Adult; Antiviral Agents; Drug Administration Schedule; Drug Resistance, Multiple, Viral; Female; Guanine; Hepatitis B; Hepatitis B virus; Humans; Lamivudine; Mutation; Organophosphonates; Viral Load | 2007 |
Ligand-induced folding of the guanine-sensing riboswitch is controlled by a combined predetermined induced fit mechanism.
Topics: Adenine; Aptamers, Nucleotide; Bacillus subtilis; Base Pairing; Base Sequence; Cations, Divalent; Guanine; Ligands; Magnesium; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Operon; Regulatory Sequences, Ribonucleic Acid; RNA, Bacterial | 2007 |
Target cell APOBEC3C can induce limited G-to-A mutation in HIV-1.
Topics: Adenine; Blotting, Western; Cell Line; Clone Cells; Cytidine Deaminase; DNA Mutational Analysis; DNA, Viral; Drug Resistance, Viral; Gene Products, vif; Genes, gag; Guanine; HIV Infections; HIV-1; Humans; Point Mutation; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Small Interfering; Transfection; Virus Replication | 2007 |
Role of APOBEC3 in genetic diversity among endogenous murine leukemia viruses.
Topics: Adenine; Animals; Binding Sites; Cytidine Deaminase; Genetic Variation; Genome; Guanine; Leukemia Virus, Murine; Mice; Mice, Inbred C57BL; Mutation; Phylogeny; Proviruses; Virus Replication | 2007 |
Inclusion kinetics of a nucleotide into a cyclodextrin cavity by means of ultrasonic relaxation.
Topics: Adenine; Adenosine Monophosphate; beta-Cyclodextrins; Guanine; Kinetics; Nucleotides; Solutions; Spectrum Analysis; Thermodynamics; Ultrasonics | 2007 |
Hepatitis B: explosion of new knowledge.
Topics: Adenine; Antiviral Agents; Disease Progression; Drug Resistance, Viral; Genotype; Guanine; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Immune Tolerance; Lamivudine; Organophosphonates | 2007 |
On the position of the potential wall in DFT temporary anion calculations.
Topics: Adenine; Anions; Guanine; Models, Chemical; Models, Molecular; Molecular Structure; Quantum Theory; Sensitivity and Specificity | 2007 |
Photoelectron spectroscopy of adiabatically bound valence anions of rare tautomers of the nucleic acid bases.
Topics: Adenine; Anions; Base Composition; Chemistry, Physical; Cytosine; DNA; Electrons; Guanine; Ions; Light; Models, Chemical; Molecular Conformation; Nucleic Acid Conformation; Nucleic Acids; RNA; Spectrophotometry; Thymine; Uracil | 2007 |
Detection of unrecognized low-level mtDNA heteroplasmy may explain the variable phenotypic expressivity of apparently homoplasmic mtDNA mutations.
Topics: Adenine; Adult; Audiometry, Pure-Tone; Base Sequence; Child; Child, Preschool; Chromatography, High Pressure Liquid; Conserved Sequence; Cytochromes b; DNA Mutational Analysis; DNA, Mitochondrial; Female; Guanine; Humans; Inheritance Patterns; Male; Molecular Sequence Data; Mutation; Pedigree; Phenotype | 2008 |
DNA oligonucleotides with A, T, G or C opposite an abasic site: structure and dynamics.
Topics: Adenine; Base Pairing; Base Sequence; Carbohydrate Conformation; Computer Simulation; Cytosine; Deoxyribose; DNA; DNA Damage; Guanine; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Oligodeoxyribonucleotides; Phosphates; Protons; Thymine | 2008 |
Unnatural substrates reveal the importance of 8-oxoguanine for in vivo mismatch repair by MutY.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenine; Base Pairing; Base Sequence; Deoxyguanosine; DNA Damage; DNA Glycosylases; DNA Mismatch Repair; Escherichia coli; Guanine; Kinetics; Molecular Sequence Data; Oligonucleotides; Plasmids; Substrate Specificity | 2008 |
Development of a new method for the synthesis of oligodeoxynucleotides by use of carbamoyl-type protecting groups.
Topics: Adenine; Biochemistry; Cytosine; Guanine; Oligodeoxyribonucleotides; Sulfonamides; Temperature | 2007 |
Frequency of CEP290 c.2991_1655A>G mutation in 175 Spanish families affected with Leber congenital amaurosis and early-onset retinitis pigmentosa.
Topics: Adenine; Age of Onset; Antigens, Neoplasm; Blindness; Cell Cycle Proteins; Cohort Studies; Cytoskeletal Proteins; Gene Frequency; Guanine; Humans; Mutation; Neoplasm Proteins; Phenotype; Retinal Diseases; Retinitis Pigmentosa; Spain | 2007 |
Fluorinated methylenecyclopropane analogues of nucleosides. Synthesis and antiviral activity of (Z)- and (E)-9-{[(2-fluoromethyl-2-hydroxymethyl)-cyclopropylidene]methyl}adenine and -guanine.
Topics: Adenine; Antiviral Agents; Cell Line; Cyclopropanes; Fluorine Compounds; Guanine; Hepacivirus; Hydroxylation; Isomerism; Magnetic Resonance Spectroscopy; Methylation; Molecular Structure; Nucleosides | 2008 |
Mechanism and control of rare tautomer trapping at a metal-metal bond: adenine binding to dirhodium antitumor agents.
Topics: Adenine; Antineoplastic Agents; Guanine; Isomerism; Ligands; Mathematical Computing; Organometallic Compounds; Thermodynamics | 2008 |
Premature stop codon in MMP20 causing amelogenesis imperfecta.
Topics: Adenine; Amelogenesis Imperfecta; Child; Codon, Nonsense; Dental Enamel; Exons; Female; Guanine; Humans; Matrix Metalloproteinase 20; Point Mutation; Sequence Analysis, DNA; Tryptophan | 2008 |
Partition chromatographic separation of adenine and guanine.
Topics: Adenine; Chromatography, Liquid; Guanine | 1949 |
Chromophore/DNA interactions: femto- to nanosecond spectroscopy, NMR structure, and electron transfer theory.
Topics: Adenine; Algorithms; Aminoacridines; Base Pairing; Base Sequence; DNA; Electron Transport; Guanine; Kinetics; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Phosphates; Protons; Quantum Theory; Spectrometry, Fluorescence; Thymine | 2008 |
Transport of [14C]hypoxanthine by sheep choroid plexus epithelium as a monolayer in primary culture: Na+-dependent and Na+-independent uptake by the apical membrane and rapid intracellular metabolic conversion to nucleotides.
Topics: Adenine; Animals; Carbon Radioisotopes; Cell Membrane; Cell Membrane Permeability; Cells, Cultured; Choroid Plexus; Epithelial Cells; Guanine; Hypoxanthine; Nucleotides; Protein Transport; Sheep; Sodium; Time Factors | 2008 |
Dynamics in the DNA recognition by DAPI: exploration of the various binding modes.
Topics: Adenine; Base Pairing; Base Sequence; Binding Sites; Bisbenzimidazole; Buffers; Cytosine; DNA; Fluorescent Dyes; Guanine; Indoles; Intercalating Agents; Oligonucleotides; Solvents; Spectrometry, Fluorescence; Thymine; Time Factors | 2008 |
Genetic architecture of the human tryptophan hydroxylase 2 Gene: existence of neural isoforms and relevance for major depression.
Topics: Adenine; Brain; Chromosome Mapping; Depressive Disorder, Major; Guanine; Humans; Isoenzymes; Neurons; Polymorphism, Single Nucleotide; Reverse Transcriptase Polymerase Chain Reaction; Tryptophan Hydroxylase; White People | 2008 |
Inhibition of DNA replication fork progression and mutagenic potential of 1, N6-ethenoadenine and 8-oxoguanine in human cell extracts.
Topics: Adenine; Cell Extracts; Cell Line; DNA Damage; DNA Replication; DNA-Directed DNA Polymerase; Electrophoresis, Gel, Two-Dimensional; Genetic Vectors; Guanine; HeLa Cells; Humans; Mutagenesis | 2008 |
Potency of tenofovir in chronic hepatitis B: mono or combination therapy?
Topics: Adenine; Antiviral Agents; Deoxycytidine; DNA, Viral; Drug Therapy, Combination; Emtricitabine; Guanine; Hepatitis B; Hepatitis B, Chronic; Humans; Lamivudine; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Outcome; Viral Load | 2008 |
Toward the exact solution of the electronic Schrödinger equation for noncovalent molecular interactions: worldwide distributed quantum monte carlo calculations.
Topics: Adenine; Base Pairing; Cytosine; DNA; Energy Transfer; Guanine; Hydrogen Bonding; Models, Molecular; Monte Carlo Method; Quantum Theory; Thymine | 2008 |
Simple STM tip functionalization for rapid DNA sequencing: an Ab initio Green's function study.
Topics: Adenine; Base Composition; Base Pairing; Cytosine; DNA; Electrodes; Electron Transport; Gold; Guanine; Microscopy, Scanning Tunneling; Models, Chemical; Models, Molecular; Nanostructures; Nucleic Acid Conformation; Quantum Theory; Sulfur Compounds; Surface Properties; Thymine | 2008 |
A guanine-linked end-effect is a sensitive reporter of charge flow through DNA and RNA double helices.
Topics: Adenine; Base Sequence; DNA; Electrons; Guanine; Models, Biological; Molecular Sequence Data; Nucleic Acid Conformation; RNA | 2008 |
Enhancement of the transverse conductance in DNA nucleotides.
Topics: Adenine; Carbon; Cytosine; DNA; Electric Conductivity; Electrochemistry; Electrodes; Electron Transport; Gold; Guanine; Hydrogen; Models, Molecular; Models, Theoretical; Nanotubes; Nitrogen; Nucleotides; Thymine | 2008 |
Association between genetic variation in transforming growth factors beta1 and beta3 and renal dysfunction in non-diabetic Chinese.
Topics: Adenine; Adult; Aged; Aged, 80 and over; Albuminuria; Asian People; Creatinine; Cytosine; Female; Genetic Variation; Genotype; Glomerular Filtration Rate; Guanine; Heterozygote; Homozygote; Humans; Hypertension; Introns; Kidney; Kidney Diseases; Male; Middle Aged; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Sex Factors; Thymine; Transforming Growth Factor beta1; Transforming Growth Factor beta3 | 2008 |
Association of interindividual differences in p14ARF promoter methylation with single nucleotide polymorphism in primary colorectal cancer.
Topics: Adenine; Colonic Neoplasms; CpG Islands; Cytosine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; Female; Genetic Variation; Genotype; Guanine; Haplotypes; Homozygote; Humans; Linkage Disequilibrium; Male; Middle Aged; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Rectal Neoplasms; RNA, Messenger; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thymine; Tumor Suppressor Protein p14ARF | 2008 |
Interaction of DNA bases with silver nanoparticles: assembly quantified through SPRS and SERS.
Topics: Adenine; Colloids; Cytosine; DNA; Guanine; Metal Nanoparticles; Microscopy, Electron, Transmission; Silver; Spectrophotometry; Spectrum Analysis, Raman; Surface Plasmon Resonance; Thymine; X-Ray Diffraction | 2008 |
Study of the poliovirus receptor related-1 gene in Thai patients with non-syndromic cleft lip with or without cleft palate.
Topics: Adenine; Amino Acid Sequence; Case-Control Studies; Cell Adhesion Molecules; Cleft Lip; Cleft Palate; Conserved Sequence; Exons; Gene Amplification; Guanine; Heterozygote; Humans; Methionine; Mutation; Nectins; Open Reading Frames; Polymerase Chain Reaction; Protein Isoforms; Sequence Analysis, DNA; Thailand; Valine | 2008 |
Nuclear magnetic resonance investigation of primer--template models: formation of a pyrimidine bulge upon misincorporation.
Topics: Adenine; Base Pair Mismatch; Base Pairing; Cytosine; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; DNA Primers; DNA Replication; Guanine; Models, Genetic; Nuclear Magnetic Resonance, Biomolecular; Templates, Genetic; Thymidine; Thymine Nucleotides | 2008 |
Rapid and simple determination of adenine and guanine in DNA extract by micellar electrokinetic chromatography with indirect laser-induced fluorescence detection.
Topics: Adenine; Chromatography, Micellar Electrokinetic Capillary; DNA; Guanine; Hydrogen-Ion Concentration; Lasers; Sodium Dodecyl Sulfate; Spectrometry, Fluorescence; Temperature | 2008 |
Monitoring of dimethyl sulphate-induced N3-methyladenine, N7-methylguanine and O(6)-methylguanine DNA adducts using reversed-phase high performance liquid chromatography and mass spectrometry.
Topics: Adenine; Animals; Chromatography, High Pressure Liquid; DNA; DNA Adducts; Guanine; Male; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Sulfuric Acid Esters; Testis | 2008 |
Androgen receptor cytosine-adenine-guanine repeat polymorphisms modulate EGFR signaling in epithelial ovarian carcinomas.
Topics: Adenine; Alleles; Carcinoma; Cell Line, Tumor; Cell Proliferation; Cytosine; ErbB Receptors; Female; Guanine; Humans; Mitogen-Activated Protein Kinases; Ovarian Neoplasms; Phosphorylation; Polymorphism, Genetic; Receptors, Androgen; Signal Transduction; Transcriptional Activation; Transfection; Trinucleotide Repeats | 2008 |
Gastrointestinal tract involvement associated with the 3243A>G mitochondrial DNA mutation.
Topics: Adenine; Adult; Base Sequence; DNA Mutational Analysis; DNA, Mitochondrial; Electron Transport Complex IV; Energy Metabolism; Fatal Outcome; Female; Gastrointestinal Diseases; Gastrointestinal Motility; Gastrointestinal Tract; Genetic Markers; Genetic Predisposition to Disease; Genetic Testing; Guanine; Humans; MELAS Syndrome; Middle Aged; Mitochondria; Mitochondrial Diseases; Myocytes, Smooth Muscle; Point Mutation | 2008 |
Incorrect nucleotide insertion at the active site of a G:A mismatch catalyzed by DNA polymerase beta.
Topics: Adenine; Base Pair Mismatch; Binding Sites; Catalysis; Computer Simulation; DNA Polymerase beta; Guanine; Humans; Models, Molecular; Models, Theoretical; Motion; Static Electricity; Thermodynamics | 2008 |
Insights into DNA binding of ruthenium arene complexes: role of hydrogen bonding and pi stacking.
Topics: Adenine; DNA; Guanine; Hydrogen Bonding; Models, Molecular; Polycyclic Compounds; Ruthenium; Thermodynamics | 2008 |
TDP-43 mutation in familial amyotrophic lateral sclerosis.
Topics: Adenine; Aged; Amino Acid Sequence; Amyotrophic Lateral Sclerosis; Animals; Base Pairing; Cells, Cultured; Chlorocebus aethiops; COS Cells; DNA-Binding Proteins; Female; Guanine; Humans; Male; Middle Aged; Molecular Sequence Data; Mutation, Missense; Pedigree | 2008 |
Quantitative high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry analysis of the adenine-guanine cross-links of 1,2,3,4-diepoxybutane in tissues of butadiene-exposed B6C3F1 mice.
Topics: Adenine; Animals; Butadienes; Cattle; Chromatography, High Pressure Liquid; Cross-Linking Reagents; DNA; Epoxy Compounds; Guanine; Hydrolysis; Kinetics; Mice; Molecular Structure; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Tandem Mass Spectrometry | 2008 |
A study of oxaliplatin-nucleobase interactions using ion trap electrospray mass spectrometry.
Topics: Adenine; Cytosine; DNA Adducts; Guanine; Organoplatinum Compounds; Oxaliplatin; Spectrometry, Mass, Electrospray Ionization; Thymine | 2008 |
Mitochondrial DNA polymorphism A4917G is independently associated with age-related macular degeneration.
Topics: Adenine; Aged; Aging; Apolipoproteins E; DNA Primers; DNA, Mitochondrial; Female; Fluorescein Angiography; Genome; Guanine; Humans; Macular Degeneration; Male; Middle Aged; Polymorphism, Single Nucleotide; Reference Values; White People | 2008 |
[Acute hepatitis B: is antiviral therapy indicated? Two case reports].
Topics: Acute Disease; Adenine; Adult; Algorithms; Antiviral Agents; Bilirubin; DNA, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Lamivudine; Liver; Middle Aged; Organophosphonates; Prothrombin Time; Transaminases; Treatment Failure; Treatment Outcome | 2008 |
Excess of transmission of the G allele of the -1438A/G polymorphism of the 5-HT2A receptor gene in patients with schizophrenia responsive to antipsychotics.
Topics: Adenine; Adult; Algeria; Antipsychotic Agents; Clozapine; Diagnostic and Statistical Manual of Mental Disorders; Family; Female; Gene Frequency; Guanine; Haloperidol; Humans; Lithium Carbonate; Male; Patient Selection; Polymorphism, Single Nucleotide; Psychiatric Status Rating Scales; Receptor, Serotonin, 5-HT2A; Risperidone; Schizophrenia; Treatment Outcome | 2008 |
The effects of alternate polypurine tracts (PPTs) and mutations of sequences adjacent to the PPT on viral replication and cleavage specificity of the Rous sarcoma virus reverse transcriptase.
Topics: Adenine; Animals; Base Sequence; Cell Line; Cells, Cultured; Chick Embryo; Consensus Sequence; Embryo, Nonmammalian; Fibroblasts; Guanine; Molecular Sequence Data; Mutation; Purines; Ribonuclease H; RNA-Directed DNA Polymerase; Rous sarcoma virus; Sensitivity and Specificity; Terminal Repeat Sequences | 2008 |
The electron affinities of deprotonated adenine, guanine, cytosine, uracil, and thymine.
Topics: Adenine; Cytosine; Electrons; Gas Chromatography-Mass Spectrometry; Gases; Guanine; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Photochemistry; Protons; Purines; Pyrimidines; Thermodynamics; Thymine; Uracil | 2008 |
Antiviral resistance mutations potentiate hepatitis B virus immune evasion through disruption of its surface antigen a determinant.
Topics: Adenine; Animals; Antibodies, Monoclonal; Antigen-Antibody Reactions; Antiviral Agents; CHO Cells; Cricetinae; Cricetulus; Drug Resistance, Multiple, Viral; Enzyme-Linked Immunosorbent Assay; Epitope Mapping; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Viral; Gene Products, pol; Guanine; Hepatitis B Antibodies; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Immunodominant Epitopes; Lamivudine; Mutagenesis, Site-Directed; Mutation; Organophosphonates; Transfection | 2008 |
Liquid-crystal NMR structure of HIV TAR RNA bound to its SELEX RNA aptamer reveals the origins of the high stability of the complex.
Topics: Adenine; Aptamers, Nucleotide; Base Pairing; Guanine; HIV; HIV Long Terminal Repeat; Hydrogen Bonding; Liquid Crystals; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; RNA, Viral; SELEX Aptamer Technique; Thermodynamics | 2008 |
Formation of purine-purine mispairs by Sulfolobus solfataricus DNA polymerase IV.
Topics: Adenine; Archaeal Proteins; Base Pair Mismatch; Base Pairing; DNA Damage; DNA Polymerase beta; DNA Replication; Guanine; Hydrogen Bonding; Kinetics; Molecular Structure; Purines; Sulfolobus solfataricus | 2008 |
Selection of an entecavir-resistant mutant despite prolonged hepatitis B virus DNA suppression, in a chronic hepatitis B patient with preexistent lamivudine resistance: successful rescue therapy with tenofovir.
Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Drug Resistance, Multiple, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Organophosphonates; Tenofovir; Viral Load | 2008 |
Single base interrogation by a fluorescent nucleotide: each of the four DNA bases identified by fluorescence spectroscopy.
Topics: Adenine; Chromatography, High Pressure Liquid; Cytosine; DNA; Fluorescent Dyes; Guanine; Nucleosides; Spectrometry, Fluorescence; Thymine | 2008 |
Genetic evidence for the essential role of PfNT1 in the transport and utilization of xanthine, guanine, guanosine and adenine by Plasmodium falciparum.
Topics: Adenine; Animals; Biological Transport; Erythrocytes; Gene Deletion; Guanine; Guanosine; Membrane Transport Proteins; Plasmodium falciparum; Protozoan Proteins; Purines; Xanthine | 2008 |
Electrochemical determination of antioxidant capacities in flavored waters by guanine and adenine biosensors.
Topics: Adenine; Antioxidants; Beverages; Biosensing Techniques; Electrochemistry; Equipment Design; Equipment Failure Analysis; Food Analysis; Guanine; Reproducibility of Results; Sensitivity and Specificity; Water | 2008 |
Interaction of the DNA bases and their mononucleotides with pyridine-2-carbaldehyde thiosemicarbazonecopper(II) complexes. Structure of the cytosine derivative.
Topics: Adenine; Adenine Nucleotides; Copper; Crystallography, X-Ray; Cytosine; Cytosine Nucleotides; DNA; Guanine; Guanine Nucleotides; Nucleotides; Organometallic Compounds; Purines; Pyridines; Pyrimidines; Thiosemicarbazones | 2008 |
Entecavir therapy for adefovir-resistant hepatitis B virus infection in kidney and liver allograft recipients.
Topics: Adenine; Adult; Antiviral Agents; Drug Resistance, Viral; Guanine; Hepatitis B; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Kidney Transplantation; Liver Function Tests; Liver Transplantation; Male; Middle Aged; Organophosphonates; Pilot Projects; Prothrombin Time | 2008 |
Kinetics of charge transfer in DNA containing a mismatch.
Topics: Adenine; Base Pair Mismatch; DNA; Guanine; Kinetics; Polymorphism, Single Nucleotide; Sequence Analysis, DNA; Thymine | 2008 |
Association between lysyl oxidase polymorphisms and oral submucous fibrosis in older male areca chewers.
Topics: Adenine; Age Factors; Alleles; Amino Acid Sequence; Areca; Arginine; Genetic Predisposition to Disease; Genotype; Glutamine; Guanine; Heterozygote; Humans; Male; Middle Aged; Oral Submucous Fibrosis; Polymorphism, Single Nucleotide; Precancerous Conditions; Protein-Lysine 6-Oxidase; Risk Factors | 2009 |
The carcinogenic air pollutant 3-nitrobenzanthrone induces GC to TA transversion mutations in human p53 sequences.
Topics: Adenine; Air Pollutants; Animals; Benz(a)Anthracenes; Carcinogens, Environmental; Cell Line; Cytosine; DNA Adducts; Guanine; Humans; Mice; Mutagenesis; Mutagens; Mutation; Thymine; Tumor Suppressor Protein p53; Vehicle Emissions | 2009 |
Sporadic desmoid tumor in an Ashkenazi patient homozygous for the APC*I1307K gene mutation.
Topics: Adenine; Adult; beta Catenin; Female; Fibromatosis, Aggressive; Genes, APC; Germ-Line Mutation; Guanine; Homozygote; Humans; Isoleucine; Jews; Lysine; Sequence Analysis, DNA | 2008 |
Thermodynamic studies of interactions of calf spleen PNP with acyclic phosphonate inhibitors.
Topics: Adenine; Animals; Enzyme Inhibitors; Guanine; Organophosphonates; Organophosphorus Compounds; Purine-Nucleoside Phosphorylase; Spleen; Thermodynamics | 2008 |
Simple and universal method to determine dissociation constants for enzyme/ligand complexes.
Topics: Adenine; Biochemistry; Enzyme Stability; Guanine; Hot Temperature; Kinetics; Ligands; Organophosphorus Compounds; Phosphates; Purine-Nucleoside Phosphorylase; Spectrophotometry | 2008 |
Direct electrocatalytic oxidation of adenine and guanine on carbon ionic liquid electrode and the simultaneous determination.
Topics: Adenine; Biosensing Techniques; Catalysis; Complex Mixtures; Electrochemistry; Electrodes; Equipment Design; Equipment Failure Analysis; Guanine; Ionic Liquids; Oxidation-Reduction; Reproducibility of Results; Sensitivity and Specificity | 2008 |
Binding of DNA nucleobases and nucleosides with graphene.
Topics: Adenine; Cytosine; Graphite; Guanine; Nucleosides; Thermodynamics; Thymine | 2009 |
Mitochondrial tRNAThr G15927A mutation may modulate the phenotypic manifestation of ototoxic 12S rRNA A1555G mutation in four Chinese families.
Topics: Adenine; Aminoacylation; Aminoglycosides; Asian People; Base Sequence; Cell Line; China; Connexin 26; Connexins; Deafness; DNA Mutational Analysis; Family; Female; Genome, Mitochondrial; Guanine; Hearing Tests; Humans; Male; Mitochondria; Mitochondrial Proteins; Molecular Sequence Data; Mutation; Nucleic Acid Conformation; Pedigree; Phenotype; RNA, Ribosomal; RNA, Transfer, Thr; tRNA Methyltransferases | 2008 |
Correlation of molecular orientation and packing density in a dsDNA self-assembled monolayer observable with surface-enhanced Raman spectroscopy.
Topics: Adenine; DNA; Gold; Guanine; Metal Nanoparticles; Models, Molecular; Nucleic Acid Conformation; Reference Standards; Spectrum Analysis, Raman; Sulfhydryl Compounds; Surface Properties | 2008 |
Head-to-head right-handed cross-links of the antitumor-active bis(mu-N,N'-di-p-tolylformamidinato)dirhodium(II,II) unit with the dinucleotides d(GpA) and d(ApG).
Topics: Adenine; Antineoplastic Agents; DNA Adducts; Guanine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Models, Molecular; Rhodium | 2008 |
Substitution of adenine for guanine in the quadruplex-forming human telomere DNA sequence G(3)(T(2)AG(3))(3).
Topics: Adenine; Base Sequence; Circular Dichroism; DNA; G-Quadruplexes; Guanine; Humans; Nucleic Acid Conformation; Telomere | 2009 |
The utilization of adenine for nucleic acid synthesis and as a precursor of guanine.
Topics: Adenine; Guanine; Nucleic Acids | 1948 |
High-fidelity correction of genomic uracil by human mismatch repair activities.
Topics: Adenine; B-Lymphocytes; Cell Extracts; Cell Line; Cell Nucleus; DNA Mismatch Repair; DNA-Binding Proteins; DNA, Circular; Genome, Human; Guanine; Humans; Mutation; Nucleic Acid Heteroduplexes; Substrate Specificity; Uracil; Uracil-DNA Glycosidase | 2008 |
Characterization of the DNA adducts induced by aristolochic acids in oligonucleotides by electrospray ionization tandem mass spectrometry.
Topics: Adenine; Aristolochic Acids; DNA Adducts; Guanine; Oligonucleotides; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2008 |
An ab initio study of substituent effects on the excited states of purine derivatives.
Topics: 2-Aminopurine; Adenine; Electrons; Gases; Guanine; Hypoxanthine; Isomerism; Purines; Quantum Theory; Xanthine | 2008 |
Two new mutations in the keratin 4 gene causing oral white sponge nevus in Chinese family.
Topics: Adenine; Adult; China; Epithelial Cells; Exons; Female; Glutamic Acid; Guanine; Hamartoma; Humans; Keratin-13; Keratin-4; Lysine; Mouth Diseases; Mutation; Mutation, Missense; Pedigree; RNA, Untranslated | 2009 |
Excretion of urinary N7 guanine and N3 adenine DNA adducts in mice after inhalation of styrene.
Topics: Adenine; Administration, Inhalation; Animals; Chromatography, High Pressure Liquid; DNA Adducts; Guanine; Male; Mice; Styrene | 2009 |
Sensitivity and accuracy of an updated line probe assay (HBV DR v.3) in detecting mutations associated with hepatitis B antiviral resistance.
Topics: Adenine; Adult; Antiviral Agents; DNA Probes; DNA, Viral; Drug Resistance, Viral; Female; Guanine; Hepatitis B; Hepatitis B virus; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Sensitivity and Specificity | 2009 |
[Protocol for the antiviral therapy of chronic hepatitis B].
Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Interferons; Lamivudine; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Tenofovir | 2008 |
Postmortem miscoding lesions in sequence analysis of human ancient mitochondrial DNA.
Topics: Adenine; Cytosine; DNA Damage; DNA, Mitochondrial; Guanine; Humans; Sequence Analysis; Thymine | 2009 |
m.3243A>G mutation in mitochondrial DNA leads to decreased insulin sensitivity in skeletal muscle and to progressive beta-cell dysfunction.
Topics: Adenine; Adult; Diabetes Mellitus; DNA, Mitochondrial; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Glucose Clamp Technique; Guanine; Humans; Hypoglycemic Agents; Insulin; Insulin-Secreting Cells; Islets of Langerhans; Male; Middle Aged; Muscle, Skeletal; Polymorphism, Single Nucleotide; Positron-Emission Tomography; Reference Values | 2009 |
Tumor necrosis factor-alpha -308G/A single nucleotide polymorphism and red-complex periodontopathogens are independently associated with increased levels of tumor necrosis factor-alpha in diseased periodontal tissues.
Topics: Adenine; Adult; Aggregatibacter actinomycetemcomitans; Bacteroides; Chronic Periodontitis; Female; Gene Frequency; Genotype; Guanine; Humans; Male; Middle Aged; Periodontal Attachment Loss; Periodontal Pocket; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Porphyromonas gingivalis; Reverse Transcriptase Polymerase Chain Reaction; Treponema denticola; Tumor Necrosis Factor-alpha | 2009 |
Electrochemical studies on the oxidation of guanine and adenine at cyclodextrin modified electrodes.
Topics: Adenine; Adsorption; Carbon; Cyclodextrins; Electrochemistry; Guanine; Hydrogen-Ion Concentration; Microelectrodes; Oxidation-Reduction | 2008 |
Interactions of the "piano-stool" [ruthenium(II) (eta6-arene)(en)CL]+ complexes with water and nucleobases; ab initio and DFT study.
Topics: Adenine; Antineoplastic Agents; Binding Sites; Cytosine; Ethylenediamines; Guanine; Models, Molecular; Molecular Structure; Purines; Pyrimidinones; Quantum Theory; Ruthenium; Thermodynamics; Thymine; Uracil; Water | 2009 |
Structural and dynamics study of DNA dodecamer duplexes that contain un-, hemi-, or fully methylated GATC sites.
Topics: Adenine; Base Pairing; Cytosine; DNA; DNA Methylation; Guanine; Kinetics; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Thermodynamics; Thymidine | 2008 |
AtAzg1 and AtAzg2 comprise a novel family of purine transporters in Arabidopsis.
Topics: Adenine; Amino Acid Sequence; Arabidopsis; Azaguanine; Biological Transport; Guanine; Molecular Sequence Data; Nucleobase Transport Proteins; Phylogeny; Saccharomyces cerevisiae | 2009 |
A bridged nucleic acid, 2',4'-BNA COC: synthesis of fully modified oligonucleotides bearing thymine, 5-methylcytosine, adenine and guanine 2',4'-BNA COC monomers and RNA-selective nucleic-acid recognition.
Topics: 5-Methylcytosine; Adenine; Base Pair Mismatch; Bridged-Ring Compounds; Circular Dichroism; DNA; Guanine; Nucleic Acid Conformation; Nucleic Acid Denaturation; Nucleic Acids; Oligonucleotides; RNA; Thymine | 2009 |
Modeling the noncovalent interactions at the metabolite binding site in purine riboswitches.
Topics: Adenine; Aptamers, Nucleotide; Base Sequence; Binding Sites; Crystallization; Guanine; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Quantum Theory; Thermodynamics | 2009 |
Management of medullary carcinoma of the thyroid during pregnancy in a patient with an intron substitution.
Topics: Adenine; Carcinoma, Medullary; Combined Modality Therapy; Exons; Female; Genetic Therapy; Guanine; Humans; Infant, Newborn; Introns; Lymphatic Metastasis; Multiple Endocrine Neoplasia Type 2a; Neck Dissection; Polymorphism, Single Nucleotide; Pregnancy; Pregnancy Complications, Neoplastic; Pregnancy, High-Risk; Proto-Oncogene Proteins c-ret; Thyroid Gland; Thyroid Neoplasms; Thyroidectomy; Tourette Syndrome; Young Adult | 2008 |
Thermodynamics of G x A mispairs in DNA: continuum electrostatic model.
Topics: Adenine; Base Pair Mismatch; DNA; Guanine; Models, Molecular; Nucleic Acid Conformation; Nucleic Acid Denaturation; Static Electricity; Thermodynamics | 2009 |
The relationship between -8503G/A polymorphism of adiponectin receptor 1 and insulin sensitivity in the Japanese population.
Topics: Adenine; Asian People; Drug Resistance; Guanine; Hawaii; Humans; Japan; Life Style; Los Angeles; Obesity; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Receptors, Adiponectin | 2009 |
Absorption and fluorescence emission spectroscopic characters of size-expanded yDNA bases and effect of deoxyribose and base pairing.
Topics: Adenine; Base Pairing; Cytosine; Deoxyribonucleosides; Deoxyribose; DNA; Guanine; Models, Molecular; Nucleic Acid Conformation; RNA, Transfer; Spectrometry, Fluorescence; Spectrophotometry; Spectrophotometry, Ultraviolet; Thymine | 2009 |
Desorption electrospray ionization mass spectrometry of DNA nucleobases: implications for a liquid film model.
Topics: Adenine; Cytosine; Guanine; Hydrogen-Ion Concentration; Models, Chemical; Polymethyl Methacrylate; Pressure; Solubility; Spectrometry, Mass, Electrospray Ionization; Thymine | 2009 |
Theoretical analysis on the transition state of the anticancer drug trans-[PtCl2(isopropylamine)2] and its cis isomer binding to DNA purine bases.
Topics: Adenine; Antineoplastic Agents; Binding Sites; Computer Simulation; DNA; Guanine; Models, Chemical; Organoplatinum Compounds; Stereoisomerism | 2009 |
Hepatitis B virus viral load and treatment decision.
Topics: Adenine; Algorithms; Antiviral Agents; Decision Making; DNA, Viral; Drug Resistance, Viral; Female; Guanine; Hepatitis C, Chronic; Humans; Male; Organophosphonates; Patient Selection; RNA, Viral; Tenofovir; Viral Load | 2009 |
Tumour necrosis factor alpha gene (TNF-alpha) -376 polymorphism in Hungarian patients with primary progressive multiple sclerosis.
Topics: Adenine; Adult; Female; Gene Frequency; Genetic Predisposition to Disease; Guanine; Humans; Hungary; Male; Middle Aged; Multiple Sclerosis, Chronic Progressive; Polymorphism, Genetic; Tumor Necrosis Factor-alpha | 2009 |
Recognition and processing of a new repertoire of DNA substrates by human 3-methyladenine DNA glycosylase (AAG).
Topics: Adenine; Base Sequence; Catalysis; Catalytic Domain; DNA; DNA Damage; DNA Glycosylases; DNA Repair; DNA, Single-Stranded; Electrophoretic Mobility Shift Assay; Guanine; Humans; Kinetics; Models, Molecular; Molecular Structure; Oligonucleotides; Protein Binding; Protein Structure, Tertiary; Sequence Deletion; Substrate Specificity | 2009 |
Genetic variation in the multidrug and toxin extrusion 1 transporter protein influences the glucose-lowering effect of metformin in patients with diabetes: a preliminary study.
Topics: Adenine; Aged; Aged, 80 and over; Bile; Blood Glucose; Cohort Studies; Creatinine; Diabetes Mellitus; Drug Resistance, Multiple; Epithelial Cells; Female; Genetic Variation; Genotype; Glomerular Filtration Rate; Glycated Hemoglobin; Guanine; Hepatocytes; Humans; Kidney; Male; Metformin; Organic Cation Transport Proteins; Polymorphism, Single Nucleotide; White People | 2009 |
Entecavir shows limited efficacy in HBeAg-positive hepatitis B patients with a partial virologic response to adefovir therapy.
Topics: Adenine; Adult; Aged; Antiviral Agents; DNA, Viral; Female; Genotype; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; RNA, Viral; Treatment Outcome; Viral Load; Young Adult | 2009 |
Partial virological response to nucleos(t)ide analogues in naïve patients with chronic hepatitis B: From guidelines to field practice.
Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Nucleosides; Nucleotides; Organophosphonates; Tenofovir | 2009 |
Structural polymorphism of the four-repeat Oxytricha nova telomeric DNA sequences.
Topics: Adenine; Animals; Autoradiography; Circular Dichroism; DNA, Protozoan; Electrophoresis, Polyacrylamide Gel; G-Quadruplexes; Guanine; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Oxytricha; Phosphorus Radioisotopes; Sodium; Thymine | 2009 |
The rtA194T polymerase mutation impacts viral replication and susceptibility to tenofovir in hepatitis B e antigen-positive and hepatitis B e antigen-negative hepatitis B virus strains.
Topics: Adenine; Anti-HIV Agents; Cell Line, Tumor; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Guanine; Hepatitis B; Hepatitis B e Antigens; Hepatitis B virus; Humans; Lamivudine; Mutation; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Viral Proteins; Virus Replication | 2009 |
Photodamage to isolated mononucleotides--photodissociation spectra and fragment channels.
Topics: Adenine; Cytosine; Guanine; Photochemistry; Spectrometry, Mass, Electrospray Ionization; Spectrum Analysis; Thymine; Ultraviolet Rays | 2009 |
Decision analysis model for hepatitis B prophylaxis one year after liver transplantation.
Topics: Adenine; Administration, Oral; Antiviral Agents; Cost Savings; Cost-Benefit Analysis; Decision Support Techniques; Drug Costs; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Health Care Costs; Hepatitis B, Chronic; Humans; Immunoglobulins; Injections, Intramuscular; Lamivudine; Liver Transplantation; Markov Chains; Models, Economic; Organophosphonates; Retrospective Studies; Salvage Therapy; Secondary Prevention; Tenofovir; Time Factors; Treatment Failure; Treatment Outcome | 2009 |
Candidate gene strategy reveals ENAM mutations.
Topics: Adenine; Amelogenesis Imperfecta; Amino Acid Sequence; Codon, Nonsense; Dental Enamel Hypoplasia; Dental Enamel Proteins; Exons; Female; Frameshift Mutation; Genes, Dominant; Genes, Recessive; Guanine; Homeodomain Proteins; Homozygote; Humans; Introns; Male; Mutagenesis, Insertional; Sequence Deletion; Thymine; Transcription Factors | 2009 |
A ditopic ion-pair receptor based on stacked nucleobase quartets.
Topics: Adenine; Guanine; Ions; Sodium Chloride; Water | 2009 |
Structural studies of an RNA aptamer containing GGA repeats under ionic conditions using microchip electrophoresis, circular dichroism, and 1D-NMR.
Topics: Adenine; Animals; Aptamers, Nucleotide; Base Sequence; Cattle; Circular Dichroism; Electrophoresis, Microchip; G-Quadruplexes; Guanine; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Prions; Sodium; Trinucleotide Repeats | 2009 |
Anti-hepatitis B virus activity in vitro of combinations of tenofovir with nucleoside/nucleotide analogues.
Topics: Adenine; Antiviral Agents; Cell Line; Cell Survival; Deoxycytidine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Emtricitabine; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Nucleotides; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine | 2009 |
Genetic polymorphisms in CYP3A5 and MDR1 genes and their correlations with plasma levels of tacrolimus and cyclosporine in renal transplant recipients.
Topics: Adenine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Cytochrome P-450 CYP3A; DNA Primers; Female; Guanine; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Tacrolimus; Thymine | 2009 |
In vivo modulation of angiogenic gene expression by acyclic nucleoside phosphonates PMEDAP and PMEG.
Topics: Adenine; Animals; Epidermal Growth Factor; ErbB Receptors; Fibroblast Growth Factor 1; Gene Expression Regulation, Neoplastic; Guanine; Lymphoma, T-Cell; Male; Neovascularization, Pathologic; Organophosphorus Compounds; Platelet-Derived Growth Factor; Rats; Rats, Sprague-Dawley; Receptor, Fibroblast Growth Factor, Type 1; Receptor, Platelet-Derived Growth Factor beta; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1 | 2009 |
Current trends in chronic hepatitis B management: results of a questionnaire.
Topics: Adenine; Adult; Antiviral Agents; Biopsy; Clinical Competence; Drug Administration Schedule; Family Health; Guanine; Hepatitis B e Antigens; Hepatitis B Vaccines; Hepatitis B, Chronic; Humans; Interferons; Lamivudine; Liver; Male; Middle Aged; Organophosphonates; Practice Patterns, Physicians'; Spain; Surveys and Questionnaires | 2009 |
Improved phosphoramidite building blocks for the synthesis of the simplified nucleic acid GNA.
Topics: Adenine; Formamides; Glycols; Guanine; Nucleic Acids; Oligonucleotides; Organophosphorus Compounds | 2009 |
Flexibility promotes fidelity.
Topics: Adenine; Animals; Base Pair Mismatch; DNA Mismatch Repair; DNA-Directed DNA Polymerase; Guanine; Humans | 2009 |
MMP-13 promoter polymorphisms in patients with chronic periodontitis: effects on GCF MMP-13 levels and outcome of periodontal therapy.
Topics: Adenine; Adult; Aged; Alveolar Bone Loss; Chronic Periodontitis; Dental Scaling; DNA; Female; Follow-Up Studies; Gene Frequency; Genetic Predisposition to Disease; Genotype; Gingival Crevicular Fluid; Gingival Hemorrhage; Guanine; Humans; INDEL Mutation; Male; Matrix Metalloproteinase 13; Middle Aged; Periodontal Attachment Loss; Polymorphism, Genetic; Promoter Regions, Genetic; Root Planing; Sequence Analysis, DNA; Treatment Outcome | 2009 |
A CA(+) pair adjacent to a sheared GA or AA pair stabilizes size-symmetric RNA internal loops.
Topics: Adenine; Base Pairing; Base Sequence; Cytosine; Guanine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Nucleic Acid Conformation; Oligonucleotides; RNA; RNA Stability; Thermodynamics | 2009 |
Characterization of hepatitis B virus reverse transcriptase sequences in Chinese treatment naive patients.
Topics: Adenine; Adult; Antiviral Agents; Asian People; Base Composition; China; Computational Biology; Databases, Genetic; DNA, Viral; Drug Resistance, Viral; Female; Genotype; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Phenotype; Phylogeny; RNA-Directed DNA Polymerase; Treatment Failure; Virus Replication; Young Adult | 2009 |
Molecular dynamics simulation study of the binding of purine bases to the aptamer domain of the guanine sensing riboswitch.
Topics: Adenine; Aptamers, Nucleotide; Base Sequence; Computer Simulation; Guanine; Ligands; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Untranslated Regions | 2009 |
Molecular adaptation in RNA complexes.
Topics: 5' Untranslated Regions; Adenine; Aptamers, Nucleotide; Base Pairing; Base Sequence; Binding Sites; Guanine; Hydrogen Bonding; Ligands; Molecular Structure; Nucleic Acid Conformation; Purines; RNA | 2009 |
Adaptive ligand binding by the purine riboswitch in the recognition of guanine and adenine analogs.
Topics: Adenine; Base Pairing; Base Sequence; Binding Sites; Guanine; Hydrogen Bonding; Hydrogen-Ion Concentration; Ligands; Models, Molecular; Molecular Sequence Data; Molecular Structure; Nucleic Acid Conformation; Purines; RNA; RNA, Bacterial; Substrate Specificity | 2009 |
Classification and energetics of the base-phosphate interactions in RNA.
Topics: Adenine; Base Pairing; Base Sequence; Binding Sites; Conserved Sequence; Cytosine; Guanine; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Phosphates; Quantum Theory; RNA; RNA, Ribosomal; Sequence Homology, Nucleic Acid; Uracil | 2009 |
Interleukin-6 (G-174C) and tumour necrosis factor-alpha (G-308A) gene polymorphisms in geriatric patients with chronic periodontitis.
Topics: Adenine; Aged; Alleles; Alveolar Bone Loss; Chronic Periodontitis; Cytosine; Disease Progression; Female; Gene Frequency; Genotype; Gingival Hemorrhage; Guanine; Humans; Interleukin-6; Periodontal Attachment Loss; Polymorphism, Genetic; Promoter Regions, Genetic; Tumor Necrosis Factor-alpha | 2010 |
UNA (unlocked nucleic acid): a flexible RNA mimic that allows engineering of nucleic acid duplex stability.
Topics: Adenine; Circular Dichroism; Cytosine; Guanine; Nucleic Acid Conformation; Nucleic Acid Denaturation; Organophosphorus Compounds; RNA; RNA Stability; Temperature; Uracil | 2009 |
Bond breaks of nucleotides by dissociative electron transfer of nonequilibrium prehydrated electrons: a new molecular mechanism for reductive DNA damage.
Topics: Adenine; Cytosine; DNA; DNA Damage; Electrons; Guanine; Nucleotides; Oxidation-Reduction; Radiation, Ionizing; Spectrum Analysis; Thymidine; Water | 2009 |
Different models of HBeAg seroconversion predicated by on-treatment ALT and HBV DNA profiles.
Topics: Adenine; Adult; Aged; Alanine Transaminase; Antiviral Agents; DNA, Viral; Female; Follow-Up Studies; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Nucleosides; Organophosphonates; Prognosis; Pyrimidinones; Retrospective Studies; Telbivudine; Thymidine; Young Adult | 2009 |
Interaction between cytochrome P450 1A2 genetic polymorphism and cigarette smoking on the risk of hepatocellular carcinoma in a Japanese population.
Topics: Adenine; Adult; Age Distribution; Aged; Carcinoma, Hepatocellular; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Female; Guanine; Humans; Incidence; Japan; Liver Diseases; Liver Neoplasms; Male; Middle Aged; Odds Ratio; Outpatients; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Risk Factors; Smoking | 2009 |
Low efficacy of entecavir therapy in adefovir-refractory hepatitis B patients with prior lamivudine resistance.
Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Female; Follow-Up Studies; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Treatment Outcome; Viral Load | 2010 |
Chronic hepatitis B: update 2009.
Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B, Chronic; Humans; Organophosphonates; Practice Guidelines as Topic; Tenofovir | 2009 |
Hepatitis B in HIV patients: what is the current treatment and what are the challenges?
Topics: Adenine; Antiviral Agents; Deoxycytidine; DNA, Viral; Drug Therapy, Combination; Emtricitabine; Guanine; Hepatitis B Surface Antigens; Hepatitis B, Chronic; HIV Infections; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Liver Cirrhosis; Nucleosides; Organophosphonates; Polyethylene Glycols; Pyrimidinones; Recombinant Proteins; Telbivudine; Tenofovir; Thymidine; Transaminases | 2009 |
Gas-phase thermochemical properties of the damaged base O(6)-methylguanine versus adenine and guanine.
Topics: Adenine; Computer Simulation; Gases; Guanine; Kinetics; Models, Chemical; Thermodynamics | 2009 |
Association between IRF6 SNPs and oral clefts in West China.
Topics: Adenine; Alleles; Case-Control Studies; Child; China; Cleft Lip; Cleft Palate; Cytosine; Female; Gene Frequency; Genetic Variation; Guanine; Haplotypes; Humans; Infant; Interferon Regulatory Factors; Male; Polymorphism, Single Nucleotide; Thymine; Valine | 2009 |
An isostructural G-G to A-A substitution within the HIV RRE RNA switches the specificity towards arginine-rich peptides.
Topics: Adenine; Arginine; Base Pairing; Binding Sites; Guanine; HIV; Mutation; Peptides; Response Elements; rev Gene Products, Human Immunodeficiency Virus | 2009 |
Molecular basis of transcriptional mutagenesis at 8-oxoguanine.
Topics: Adenine; Crystallography, X-Ray; DNA, Fungal; Guanine; Mutagenesis; Protein Conformation; RNA Polymerase II; RNA, Fungal; Saccharomyces cerevisiae; Transcription, Genetic | 2009 |
Lack of association between IRF6 polymorphisms (rs2235371 and rs642961) and non-syndromic cleft lip and/or palate in a Brazilian population.
Topics: Adenine; Alleles; Brazil; Case-Control Studies; Cleft Lip; Cleft Palate; Gene Frequency; Genetic Predisposition to Disease; Genotype; Guanine; Haplotypes; Humans; Interferon Regulatory Factors; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length | 2010 |
Amide linkage isomerism as an activity switch for organometallic osmium and ruthenium anticancer complexes.
Topics: Adenine; Amides; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; DNA; Guanine; Humans; Hydrogen-Ion Concentration; Hydrolysis; Isomerism; Kinetics; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Organometallic Compounds; Osmium; Picolinic Acids; Quantum Theory; Ruthenium; Thermodynamics | 2009 |
Two types of drug-resistant hepatitis B viral strains emerging alternately and their susceptibility to combination therapy with entecavir and adefovir.
Topics: Adenine; Antiviral Agents; Drug Therapy, Combination; Guanine; Hepatitis B; Hepatitis B virus; Humans; Male; Middle Aged; Organophosphonates | 2009 |
Further evidence for an association between mandibular height and the growth hormone receptor gene in a Japanese population.
Topics: Adenine; Adolescent; Adult; Asian People; Black or African American; Cephalometry; China; Cysteine; Cytosine; Exons; Female; Gene Frequency; Genotype; Guanine; Hispanic or Latino; Humans; Japan; Linkage Disequilibrium; Male; Mandible; Middle Aged; Phenylalanine; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Proline; Receptors, Somatotropin; Threonine; Thymine; White People; Young Adult | 2009 |
Association of PTPN22 C1858T and CTLA-4 A49G polymorphisms with Type 1 Diabetes in Croatians.
Topics: Adenine; Adult; Age of Onset; Antigens, CD; Blood Glucose; Croatia; CTLA-4 Antigen; Cytosine; Diabetes Mellitus, Type 1; DNA Primers; Genetic Variation; Genotype; Glycated Hemoglobin; Guanine; Humans; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Reference Values; Risk Assessment; Thymine | 2009 |
[The efficacy of nucleoside/nucleotide analogue on chronic hepatitis B].
Topics: Adenine; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine; Treatment Outcome; Virus Replication | 2009 |
Single nucleotide polymorphisms of complement component 5 and periodontitis.
Topics: Adenine; Adolescent; Adult; Age Factors; Aggressive Periodontitis; Case-Control Studies; Chronic Periodontitis; Complement C5; Cytosine; Female; Gene Frequency; Genetic Variation; Genotype; Guanine; Haplotypes; Hong Kong; Humans; Immunologic Factors; Introns; Linkage Disequilibrium; Male; Middle Aged; Periodontitis; Polymorphism, Single Nucleotide; Risk Factors; Sex Factors; Smoking; Young Adult | 2010 |
Evolution of hepatitis B virus mutation during entecavir rescue therapy in patients with antiviral resistance to lamivudine and adefovir.
Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Drug Resistance, Multiple, Viral; Evolution, Molecular; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Treatment Outcome | 2009 |
Coding region of IRF6 gene may not be causal for Van der Woude syndrome in cases from India.
Topics: 3' Untranslated Regions; Abnormalities, Multiple; Adenine; Arginine; Cleft Lip; Cleft Palate; Cohort Studies; Cytosine; Exons; Female; Genetic Variation; Genotype; Guanine; Heterozygote; Homozygote; Humans; India; Interferon Regulatory Factors; Introns; Male; Open Reading Frames; Point Mutation; Sequence Analysis, DNA; Serine; Syndrome; Thymine | 2009 |
Serological update and molecular characterization of Dirofilaria immitis in dogs, South Korea.
Topics: Adenine; Aging; Animals; Dirofilaria immitis; Dirofilariasis; Dog Diseases; Dogs; Enzyme-Linked Immunosorbent Assay; Female; Guanine; Male; Polymorphism, Single Nucleotide; Prevalence; Republic of Korea; RNA, Ribosomal, 16S; RNA, Transfer | 2010 |
Selection and counterselection of the rtI233V adefovir resistance mutation during antiviral therapy.
Topics: Adenine; Adult; Amino Acid Sequence; Amino Acid Substitution; Antiviral Agents; Drug Resistance, Viral; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Molecular Sequence Data; Mutation, Missense; Organophosphonates; Selection, Genetic; Sequence Alignment; Tenofovir; Treatment Failure; Viremia; Young Adult | 2010 |
Riboswitch structure: an internal residue mimicking the purine ligand.
Topics: 5' Untranslated Regions; Adenine; Aptamers, Nucleotide; Bacillus subtilis; Base Sequence; Binding Sites; Crystallography, X-Ray; Guanine; Ligands; Models, Molecular; Molecular Sequence Data; Mutation; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Regulatory Sequences, Ribonucleic Acid; RNA, Bacterial | 2010 |
[Protocol for the antiviral therapy of hepatitis B and D].
Topics: Adenine; Antiviral Agents; Biopsy; Guanine; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis D; HIV Infections; Humans; Interferon alpha-2; Interferon-alpha; Interferons; Lamivudine; Liver Cirrhosis; Nucleotides; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Tenofovir | 2010 |
Energy barriers between H-bonded and stacked structures of 9-methyladenine...1-methylthymine and 9-methylguanine...1-methylcytosine complexes.
Topics: Adenine; Base Pairing; Cytosine; Guanine; Hydrogen Bonding; Models, Molecular; Thermodynamics; Thymine | 2010 |
Heavy involvement of stringent transcription control depending on the adenine or guanine species of the transcription initiation site in glucose and pyruvate metabolism in Bacillus subtilis.
Topics: Adenine; Adenosine; Bacillus subtilis; Bacterial Proteins; Base Sequence; DNA, Bacterial; Gene Expression Regulation, Bacterial; Glucose; Guanine; Operon; Pyruvic Acid; Transcription Initiation Site; Transcription, Genetic | 2010 |
Characterization of mutations in the FOXE1 gene in a cohort of unrelated Malaysian patients with congenital hypothyroidism and thyroid dysgenesis.
Topics: Adenine; Amino Acid Sequence; Animals; Cohort Studies; Congenital Abnormalities; DNA Primers; Forkhead Transcription Factors; Gene Amplification; Genes, Reporter; Guanine; Hep G2 Cells; Humans; Hypothyroidism; Malaysia; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Polymorphism, Single-Stranded Conformational; Promoter Regions, Genetic; Reference Values; Sequence Alignment; Sequence Homology, Amino Acid; Thyroid Dysgenesis; Transfection | 2010 |
The electrochemical reduction of the purines guanine and adenine at platinum electrodes in several room temperature ionic liquids.
Topics: Adenine; Dimerization; Electrochemical Techniques; Electrodes; Guanine; Ionic Liquids; Oxidation-Reduction; Platinum; Temperature | 2010 |
IRF6 gene variants in Central European patients with non-syndromic cleft lip with or without cleft palate.
Topics: Adenine; Alleles; Case-Control Studies; Cleft Lip; Cleft Palate; Cytosine; Europe; Female; Gene Frequency; Genetic Loci; Genetic Variation; Genotype; Guanine; Haplotypes; Heterozygote; Homozygote; Humans; Interferon Regulatory Factors; Male; Open Reading Frames; Polymorphism, Single Nucleotide; Thymine; Valine | 2009 |
Association between TGFB3 and nonsyndromic cleft lip with or without cleft palate in a Chilean population.
Topics: Adenine; Alleles; Case-Control Studies; Chile; Cleft Lip; Cleft Palate; Ethnicity; Gene Frequency; Genetic Variation; Genotype; Guanine; Haplotypes; Heterozygote; Humans; Linkage Disequilibrium; Phenotype; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Transforming Growth Factor beta3 | 2010 |
Interactions between DNA purines and ruthenium ammine complexes within nanostructured sol-gel silica matrixes.
Topics: Adenine; Coordination Complexes; Gels; Guanine; Nanostructures; Phase Transition; Ruthenium Compounds; Silicon Dioxide; Spectrophotometry, Ultraviolet | 2010 |
Effects of base excision repair proteins on mutagenesis by 8-oxo-7,8-dihydroguanine (8-hydroxyguanine) paired with cytosine and adenine.
Topics: Adenine; Base Sequence; Cell Line; Cytosine; Deoxyguanine Nucleotides; DNA; DNA Glycosylases; DNA Repair; Gene Knockdown Techniques; Guanine; Humans; Mutagenesis; Mutation; Plasmids; RNA, Small Interfering | 2010 |
Antiproliferative effects of octadecyloxyethyl 9-[2-(phosphonomethoxy)ethyl]guanine against Me-180 human cervical cancer cells in vitro and in vivo.
Topics: Adenine; Animals; Antineoplastic Agents; Female; Guanine; HeLa Cells; Humans; Mice; Mice, Nude; Organophosphonates; Organophosphorus Compounds; Tumor Cells, Cultured; Uterine Cervical Neoplasms | 2010 |
Liver transplantation in bearers of hepatitis B associated or not with delta hepatitis in the age of the new antiviral drugs: is hyperimmune globulin still necessary?
Topics: Adenine; Adult; Aged; Antiviral Agents; Aspartate Aminotransferases; Female; Guanine; Hepatitis B; Hepatitis B virus; Hepatitis D; Humans; Liver Transplantation; Male; Middle Aged; Organophosphonates; Polymerase Chain Reaction; Recurrence; Retrospective Studies; Young Adult | 2010 |
Heterogeneity and dynamics of the ligand recognition mode in purine-sensing riboswitches.
Topics: 2-Aminopurine; Adenine; Aptamers, Nucleotide; Base Pairing; Base Sequence; Binding Sites; Fluorescence Polarization; Guanine; Hydrogen Bonding; Ligands; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; RNA, Catalytic; Spectrometry, Fluorescence; Thermodynamics | 2010 |
The antimicrobial peptide DEFB1 is associated with caries.
Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; Aggressive Periodontitis; Alleles; Antimicrobial Cationic Peptides; beta-Defensins; Cytosine; Dental Caries; Dental Caries Susceptibility; Disease Progression; DMF Index; Female; Genetic Markers; Genetic Variation; Guanine; Haplotypes; Humans; Linkage Disequilibrium; Male; Middle Aged; Periodontitis; Pilot Projects; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Young Adult | 2010 |
Vertical ionization potentials of nucleobases in a fully solvated DNA environment.
Topics: Adenine; Alkaloids; Azocines; DNA; Guanine; Hydrogen Bonding; Quantum Theory; Quinolizines; Solvents; Static Electricity; Thymine | 2010 |
Extensive molecular dynamics simulations showing that canonical G8 and protonated A38H+ forms are most consistent with crystal structures of hairpin ribozyme.
Topics: Adenine; Catalysis; Catalytic Domain; Crystallography, X-Ray; Guanine; Molecular Dynamics Simulation; Nucleic Acid Conformation; Protons; RNA, Catalytic | 2010 |
Viral resistance in hepatitis B: prevalence and management.
Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Genetic Testing; Genotype; Guanine; Hepatitis B; Humans; Lamivudine; Nucleosides; Organophosphonates; Phenotype; Pyrimidinones; Telbivudine; Tenofovir; Thymidine | 2010 |
Mutation analysis of congenital cataract in a Chinese family identified a novel missense mutation in the connexin 46 gene (GJA3).
Topics: Adenine; Adult; Asian People; Cataract; Child, Preschool; Connexins; DNA Mutational Analysis; Female; Guanine; Humans; Male; Methionine; Mutation, Missense; Pedigree; Valine | 2010 |
Altered enamelin phosphorylation site causes amelogenesis imperfecta.
Topics: Adenine; Alleles; Amelogenesis Imperfecta; Amino Acid Sequence; Calcium; Casein Kinases; Cytosine; Dental Enamel Hypoplasia; Dental Enamel Proteins; Exons; Frameshift Mutation; Golgi Apparatus; Guanine; Humans; Leucine; Male; Mutagenesis, Insertional; Mutation, Missense; Pedigree; Phosphorylation; Sequence Deletion; Serine; Thymine; Young Adult | 2010 |
SNPs of Fc-gamma receptor genes and chronic periodontitis.
Topics: Adenine; Adult; Age Factors; Alleles; Case-Control Studies; Chronic Periodontitis; Cytosine; Female; Genotype; Guanine; Haplotypes; Hong Kong; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Receptors, IgG; Sex Factors; Smoking; Thymine | 2010 |
The excited electronic states of adenine-guanine stacked dimers in aqueous solution: a PCM/TD-DFT study.
Topics: Adenine; Dimerization; Guanine; Quantum Theory; Water | 2010 |
The UV absorption of nucleobases: semi-classical ab initio spectra simulations.
Topics: Absorption; Adenine; Cytosine; Gases; Guanine; Nucleosides; Quantum Theory; Spectrophotometry, Ultraviolet; Thymine; Uracil | 2010 |
Electron transfer from aromatic amino acids to guanine and adenine radical cations in pi stacked and T-shaped complexes.
Topics: Adenine; Amino Acids, Aromatic; Cations; Dimerization; Electrons; Guanine; Models, Molecular | 2010 |
Guanine, adenine, and hypoxanthine production in UV-irradiated formamide solutions: relaxation of the requirements for prebiotic purine nucleobase formation.
Topics: Adenine; Formamides; Guanine; Hot Temperature; Hypoxanthine; Prebiotics; Purine Nucleosides; Ultraviolet Rays | 2010 |
The properties of small Ag clusters bound to DNA bases.
Topics: Adenine; Cytosine; DNA; Guanine; Quantum Theory; Silver; Spectrometry, Fluorescence; Thymine; Time Factors | 2010 |
Evaluation of the in vitro anti-HBV activity of clevudine in combination with other nucleoside/nucleotide inhibitors.
Topics: Adenine; Anti-HIV Agents; Antiviral Agents; Arabinofuranosyluracil; Cell Line; Cells, Cultured; Drug Antagonism; Drug Synergism; Drug Therapy, Combination; Guanine; Hepatitis B virus; Hepatocytes; Humans; Lamivudine; Microbial Sensitivity Tests; Nucleosides; Nucleotides; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine | 2010 |
Dental agenesis in Kallmann syndrome individuals with FGFR1 mutations.
Topics: Adenine; Adolescent; Adult; Anodontia; Arginine; Bicuspid; Child, Preschool; Cleft Palate; Cysteine; Cytosine; Female; Glutamine; Glycine; Guanine; Humans; Incisor; Kallmann Syndrome; Male; Middle Aged; Molar; Mutation; Receptor, Fibroblast Growth Factor, Type 1; Sequence Deletion; Tooth Abnormalities; Tooth Root; Tooth, Deciduous; Tryptophan; Young Adult | 2010 |
The association of beta-fibrinogen 455 G/A gene polymorphism with left atrial thrombus and severe spontaneous echo contrast in atrial fibrillation.
Topics: Adenine; Aged; Atrial Fibrillation; Coronary Thrombosis; Cross-Sectional Studies; Diabetes Complications; Echocardiography, Transesophageal; Female; Fibrinogen; Guanine; Humans; Hypertension; Male; Middle Aged; Mitral Valve Stenosis; Polymorphism, Single Nucleotide; Thromboembolism | 2010 |
Targeted photoswitchable probe for nanoscopy of biological structures.
Topics: Adenine; Carbocyanines; Cell Line, Tumor; Fluorescent Dyes; Guanine; Humans; Image Processing, Computer-Assisted; Microscopy, Fluorescence; Microtubules; Nanostructures; Tubulin | 2010 |
Cost-effectiveness of nucleoside analog therapy for hepatitis B in China: a Markov analysis.
Topics: Adenine; Antiviral Agents; China; Cost-Benefit Analysis; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Markov Chains; Models, Economic; Models, Statistical; Monte Carlo Method; Nucleosides; Organophosphonates; Pyrimidinones; Quality-Adjusted Life Years; Reverse Transcriptase Inhibitors; Serologic Tests; Telbivudine; Thymidine | 2010 |
Long-term outcome of renal transplant recipients with chronic hepatitis B infection-impact of antiviral treatments.
Topics: Adenine; Adult; Antiviral Agents; Biomarkers; DNA, Viral; Drug Resistance, Viral; Female; Guanine; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Kidney Diseases; Kidney Transplantation; Lamivudine; Male; Middle Aged; Organophosphonates; Proportional Hazards Models; Retrospective Studies; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome; Viral Load | 2010 |
MTHFR and MSX1 contribute to the risk of nonsyndromic cleft lip/palate.
Topics: Adenine; B-Cell Lymphoma 3 Protein; Case-Control Studies; Cell Adhesion Molecules; Chromosome Mapping; Cleft Lip; Cleft Palate; Cytosine; Endothelin-1; Epistasis, Genetic; Estonia; Gene Frequency; Guanine; Haplotypes; Humans; Immunoglobulins; Intercellular Signaling Peptides and Proteins; Interferon Regulatory Factors; Jagged-2 Protein; Membrane Proteins; Methylenetetrahydrofolate Reductase (NADPH2); MSX1 Transcription Factor; Nectins; Polymorphism, Single Nucleotide; Proto-Oncogene Proteins; Risk Factors; Thymine; Transcription Factors | 2010 |
Susceptibility locus for non-syndromic cleft lip with or without cleft palate on chromosome 10q25 confers risk in Estonian patients.
Topics: Adenine; Case-Control Studies; Chromosome Mapping; Chromosomes, Human, Pair 10; Cleft Lip; Cleft Palate; Cytosine; Estonia; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Guanine; Heterozygote; Homozygote; Humans; Male; Polymorphism, Single Nucleotide; Risk Factors; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thymine | 2010 |
Peptide nucleic acid array for detection of point mutations in hepatitis B virus associated with antiviral resistance.
Topics: Adenine; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Guanine; Hepatitis B; Hepatitis B virus; Humans; Lamivudine; Microbial Sensitivity Tests; Mutation, Missense; Oligonucleotide Array Sequence Analysis; Organophosphonates; Peptide Nucleic Acids; Point Mutation; Sensitivity and Specificity | 2010 |
Identification of a novel mutation in the cornea specific keratin 12 gene causing Meesmann's corneal dystrophy in a German family.
Topics: Adenine; Aged, 80 and over; Codon; Cornea; Corneal Dystrophies, Hereditary; Exons; Female; Guanine; Heterozygote; Humans; Keratin-12; Male; Mutation, Missense; Polymorphism, Genetic | 2010 |
Acute hepatitis B infection associated with drug-resistant hepatitis B virus.
Topics: Adenine; Adult; Amino Acid Substitution; Antiviral Agents; China; DNA, Viral; Drug Resistance, Viral; Guanine; Hepatitis B; Hepatitis B virus; Humans; Lamivudine; Male; Middle Aged; Molecular Sequence Data; Mutation, Missense; Organophosphonates; Polymerase Chain Reaction; RNA-Directed DNA Polymerase; Sequence Analysis, DNA; Viral Proteins | 2010 |
Distinct modulation of telomere length in two T-lymphoblastic leukemia cell lines by cytotoxic nucleoside phosphonates PMEG and PMEDAP.
Topics: Adenine; Antineoplastic Agents; Cell Culture Techniques; Cell Line, Tumor; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Guanine; Humans; In Situ Hybridization, Fluorescence; Organophosphorus Compounds; Proto-Oncogene Proteins c-myc; Reverse Transcriptase Polymerase Chain Reaction; RNA; Telomerase; Telomere; Time Factors | 2010 |
Structural variability and the nature of intermolecular interactions in Watson-Crick B-DNA base pairs.
Topics: Adenine; Base Pairing; Cytosine; DNA; Guanine; Hydrogen Bonding; Static Electricity; Thermodynamics; Thymine | 2010 |
Molecular characterization of intrahepatic and extrahepatic hepatitis B virus (HBV) reservoirs in patients on suppressive antiviral therapy.
Topics: Adenine; Adult; Aged; Antiviral Agents; Asian People; DNA, Circular; DNA, Viral; Drug Resistance; Female; Gene Products, pol; Genetic Variation; Genome, Viral; Guanine; Hepatitis B; Hepatitis B virus; Humans; Lamivudine; Liver; Liver Transplantation; Male; Middle Aged; Organophosphonates; Phylogeny; Tenofovir; Trans-Activators; Viral Envelope Proteins; Viral Regulatory and Accessory Proteins; Virus Replication | 2011 |
Electronic and molecular structure of M-DNA fragments.
Topics: Adenine; Base Pairing; Cytosine; DNA; Electrons; Guanine; Hydrogen Bonding; Models, Molecular; Nanotechnology; Nickel; Nucleic Acid Conformation; Oligonucleotides; Protons; Quantum Theory; Thermodynamics; Thymine; Zinc | 2011 |
Lamivudine plus adefovir or entecavir for patients with chronic hepatitis B resistant to lamivudine and adefovir.
Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genes, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Viral Load | 2010 |
Rescue therapy for lamivudine-resistant chronic hepatitis B: comparison between entecavir 1.0 mg monotherapy, adefovir monotherapy and adefovir add-on lamivudine combination therapy.
Topics: Adenine; Adult; Alanine Transaminase; Antiviral Agents; Biomarkers; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Republic of Korea; Retrospective Studies; Time Factors; Treatment Outcome; Viral Load; Virus Replication | 2010 |
Electronic parameters for charge transfer along DNA.
Topics: Adenine; Base Pairing; Binding Sites; Cytosine; DNA; Electron Transport; Electrons; Guanine; Models, Molecular; Thymine | 2010 |
Bioinspired blend membranes based on adenine and guanine functional poly(glycidyl methacrylate).
Topics: Adenine; Epoxy Compounds; Guanine; Magnetic Resonance Spectroscopy; Membranes, Artificial; Methacrylates; Polymers; Spectroscopy, Fourier Transform Infrared; Temperature | 2010 |
Direct voltammetric analysis of DNA modified with enzymatically incorporated 7-deazapurines.
Topics: Adenine; Carbon; DNA; Electrochemical Techniques; Electrodes; Enzymes; Guanine; Oxidation-Reduction; Polymerase Chain Reaction | 2010 |
Nearest-neighbor nitrogen and oxygen distances in the iron(II)-DNA complex studied by extended X-ray absorption fine structure.
Topics: Adenine; Animals; Cells; Coordination Complexes; Cytosine; DNA; DNA Damage; Guanine; Humans; Hydrogen Peroxide; Iron; Nitrogen; Nucleic Acid Conformation; Oxygen; Spectrum Analysis; X-Rays | 2010 |
Polymorphisms in the Matrilin-1 gene and risk of mandibular prognathism in Koreans.
Topics: Adenine; Adult; Cartilage Oligomeric Matrix Protein; Case-Control Studies; Cytosine; Exons; Extracellular Matrix Proteins; Female; Gene Frequency; Genetic Linkage; Genetic Markers; Genetic Predisposition to Disease; Genotype; Glycoproteins; Guanine; Haplotypes; Humans; Korea; Male; Matrilin Proteins; Polymorphism, Single Nucleotide; Prognathism; Promoter Regions, Genetic; Risk Factors; Thymine; Young Adult | 2010 |
Tumour necrosis factor-alpha gene polymorphisms and susceptibility to oral lichen planus.
Topics: Adenine; Adult; Cytosine; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Guanine; Haplotypes; Humans; Lichen Planus, Oral; Male; Middle Aged; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Thailand; Tumor Necrosis Factor-alpha | 2011 |
CRISPLD2 variants including a C471T silent mutation may contribute to nonsyndromic cleft lip with or without cleft palate.
Topics: Adenine; Alternative Splicing; Asian People; Case-Control Studies; Cell Adhesion Molecules; Cleft Lip; Cleft Palate; Cohort Studies; Cytosine; Enhancer Elements, Genetic; Exons; Gene Frequency; Genetic Variation; Genotype; Guanine; Haplotypes; Heterozygote; Hispanic or Latino; Humans; Interferon Regulatory Factors; Linkage Disequilibrium; Mutation; Polymorphism, Single Nucleotide; Sp1 Transcription Factor; Thymine; Transcription Factor AP-2; White People | 2011 |
Effect of substituents of alloxazine derivatives on the selectivity and affinity for adenine in AP-site-containing DNA duplexes.
Topics: Adenine; Base Sequence; Binding Sites; DNA; Flavins; Guanine; Ligands; Models, Molecular; Pteridines; Spectrometry, Fluorescence | 2010 |
A six-generation Chinese family in haplogroup B4C1C exhibits high penetrance of 1555A > G-induced hearing Loss.
Topics: Adenine; Aminoglycosides; Asian People; China; Connexin 26; Connexins; Deafness; DNA Mutational Analysis; DNA Primers; DNA, Mitochondrial; Female; Guanine; Haplotypes; Hearing Loss; Humans; Male; Mitochondria; Mitochondrial Proteins; Mutation; Pedigree; Polymorphism, Single Nucleotide; tRNA Methyltransferases | 2010 |
Cost-utility analysis of tenofovir disoproxil fumarate in the treatment of chronic hepatitis B.
Topics: Adenine; Cost-Benefit Analysis; Guanine; Hepatitis B, Chronic; Humans; Markov Chains; Organophosphonates; Quality-Adjusted Life Years; Reverse Transcriptase Inhibitors; State Medicine; Tenofovir; United Kingdom | 2010 |
Electrochemical determination of guanine and adenine by CdS microspheres modified electrode and evaluation of damage to DNA purine bases by UV radiation.
Topics: Adenine; Biosensing Techniques; Cadmium Compounds; Conductometry; DNA; DNA Damage; Equipment Design; Equipment Failure Analysis; Guanine; Purines; Sulfides | 2010 |
Antiviral treatment including entecavir plus tenofovir disoproxil fumarate for HBV reactivation following a rituximab-based regimen.
Topics: Adenine; Antibodies, Monoclonal, Murine-Derived; Antiviral Agents; Drug Combinations; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lymphoma, Non-Hodgkin; Middle Aged; Organophosphonates; Rituximab; Tenofovir; Virus Activation | 2010 |
HBcrAg is a predictor of post-treatment recurrence of hepatocellular carcinoma during antiviral therapy.
Topics: Adenine; Adult; Aged; Antiviral Agents; Carcinoma, Hepatocellular; Catheter Ablation; Disease-Free Survival; Female; Guanine; Hepatectomy; Hepatitis B Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Japan; Kaplan-Meier Estimate; Lamivudine; Liver Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Organophosphonates; Proportional Hazards Models; Risk Assessment; Risk Factors; RNA, Viral; Survival Rate; Time Factors; Treatment Outcome | 2010 |
[Antiviral treatment of chronic B hepatitis; 2010 - therapeutic recommendations].
Topics: Adenine; Antiviral Agents; Drug Administration Schedule; Drug Resistance, Viral; Guanine; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Liver; Organophosphonates; Polyethylene Glycols; Practice Guidelines as Topic; Recombinant Proteins; Tenofovir; Treatment Failure; Viral Load | 2010 |
Hypermethylation of carcinogen metabolism genes, CYP1A1, CYP2A13 and GSTM1 genes in head and neck cancer.
Topics: Adenine; Alcohol Drinking; Aryl Hydrocarbon Hydroxylases; Carcinogens; Carcinoma, Squamous Cell; CpG Islands; Cytochrome P-450 CYP1A1; Cytosine; DNA Methylation; Female; Gene Frequency; Glutathione Transferase; Guanine; Head and Neck Neoplasms; Humans; India; Laryngeal Neoplasms; Male; Middle Aged; Mouth Neoplasms; Pharyngeal Neoplasms; Polymerase Chain Reaction; Polymorphism, Genetic; Promoter Regions, Genetic; Smoking; Thymine | 2010 |
[Treatment of chronic hepatitis B. High response rate in general practice].
Topics: Adenine; Antiviral Agents; Cross-Sectional Studies; Germany; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Long-Term Care; Organophosphonates; Patient Care Team; Reverse Transcriptase Inhibitors; Tenofovir; Viral Load | 2010 |
Taste genes associated with dental caries.
Topics: Adenine; Adult; Alanine; Child; Child, Preschool; Cohort Studies; Cytosine; Dental Caries; Dental Caries Susceptibility; DMF Index; Female; Gene Frequency; Genetic Variation; Genotype; Guanine; Haplotypes; Humans; Linkage Disequilibrium; Male; Polymorphism, Single Nucleotide; Proline; Receptors, G-Protein-Coupled; Risk Factors; Taste; Thymine; Transducin; Valine | 2010 |
Coronary heart disease and chronic periodontitis: is polymorphism of interleukin-6 gene the common risk factor in a Chinese population?
Topics: Adenine; Adult; Aged; Alcohol Drinking; Case-Control Studies; China; Chromosome Mapping; Chronic Periodontitis; Coronary Disease; Cytosine; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Guanine; Humans; Hyperlipidemias; Hypertension; Interleukin-6; Male; Middle Aged; Mutation; Obesity; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Risk Factors; Smoking | 2011 |
Replication of two novel susceptibility loci for non-syndromic orofacial clefts in a Chinese population.
Topics: Adenine; Alleles; Case-Control Studies; Child; China; Chromosome Mapping; Chromosomes, Human, Pair 10; Chromosomes, Human, Pair 17; Chromosomes, Human, Pair 8; Cleft Lip; Cleft Palate; Ethnicity; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Guanine; Humans; Male; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Risk Factors | 2011 |
Structural characterization of naturally occurring RNA single mismatches.
Topics: Adenine; Base Pair Mismatch; Cytosine; Databases, Nucleic Acid; Guanine; Molecular Sequence Annotation; Nucleic Acid Conformation; RNA; Uracil | 2011 |
Computational studies on effects of MDMA as an anticancer drug on DNA.
Topics: Adenine; Antineoplastic Agents; Base Pairing; Cytosine; DNA; Drug Design; Guanine; Humans; Intercalating Agents; Molecular Conformation; Molecular Dynamics Simulation; N-Methyl-3,4-methylenedioxyamphetamine; Neoplasms; Quantum Theory; Thermodynamics; Thymine | 2010 |
Impact of hepatitis B e antigen-suppressing mutations on the replication efficiency of entecavir-resistant hepatitis B virus strains.
Topics: Adenine; Antiviral Agents; Cell Line, Tumor; Drug Resistance, Viral; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Mutation; Organophosphonates; Polymorphism, Single Nucleotide; Tenofovir; Viral Load; Viral Proteins; Virus Replication | 2011 |
Persistence and adherence to nucleos(t)ide analogue treatment for chronic hepatitis B.
Topics: Adenine; Adolescent; Adult; Antiviral Agents; Cohort Studies; Drug Resistance, Viral; Female; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Male; Medication Adherence; Middle Aged; Organophosphonates; Retrospective Studies; Tenofovir; Young Adult | 2011 |
Enhancing the antihepatitis B virus immune response by adefovir dipivoxil and entecavir therapies.
Topics: Adenine; Administration, Oral; Adult; Antiviral Agents; Case-Control Studies; Cytokines; DNA, Viral; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Immunomodulation; Lamivudine; Male; Middle Aged; Organophosphonates; T-Lymphocytes, Regulatory; Th1-Th2 Balance | 2011 |
Genetic etiology and dental pulp cell deficiency of hypophosphatasia.
Topics: Adenine; Alkaline Phosphatase; Cells, Cultured; Child; Child, Preschool; Dental Cementum; Dental Enamel; Dental Pulp; Dentin; Dentin Dysplasia; Exons; Genetic Variation; Guanine; Heterozygote; Histidine; Humans; Hypophosphatasia; Introns; Microscopy, Electron, Scanning; Mutation; Mutation, Missense; Phenotype; RNA Splice Sites; Thymine; Tooth Calcification; Tooth Exfoliation; Tyrosine | 2010 |
Association of Wnt3A gene variants with non-syndromic cleft lip with or without cleft palate in Chinese population.
Topics: Adenine; Alleles; Case-Control Studies; China; Cleft Lip; Cleft Palate; Female; Gene Frequency; Genetic Predisposition to Disease; Genetic Variation; Genotype; Guanine; Haplotypes; Homozygote; Humans; Male; Polymorphism, Single Nucleotide; Risk Factors; Sex Factors; Thymine; Wnt Proteins; Wnt3 Protein; Wnt3A Protein | 2011 |
A classification model for G-to-A hypermutation in hepatitis B virus ultra-deep pyrosequencing reads.
Topics: Adenine; Algorithms; Classification; DNA Mutational Analysis; Drug Resistance, Viral; Guanine; Hepatitis B; Hepatitis B virus; High-Throughput Nucleotide Sequencing; Humans; Models, Statistical; Mutation | 2010 |
Efficacy and safety of entecavir and/or tenofovir for prophylaxis and treatment of hepatitis B recurrence post-liver transplant.
Topics: Adenine; Adult; Aged; Antiviral Agents; Combined Modality Therapy; Female; Guanine; Hepatitis B; Humans; Liver Transplantation; Male; Middle Aged; Organophosphonates; Secondary Prevention; Tenofovir | 2010 |
Lack of modulatory function of coding nucleotide polymorphism S100A2_185G>A in oral squamous cell carcinoma.
Topics: Adenine; Adult; Aged; Alleles; Amino Acid Substitution; Asparagine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cells, Cultured; Chemotactic Factors; EF Hand Motifs; Exons; Female; Genotype; Guanine; Helix-Loop-Helix Motifs; Heterozygote; Humans; KB Cells; Keratinocytes; Male; Middle Aged; Mouth Neoplasms; Open Reading Frames; Polymorphism, Genetic; Polymorphism, Single Nucleotide; S100 Proteins; Serine; Tumor Suppressor Proteins | 2011 |
Electronic structure and spectroscopy of nucleic acid bases: ionization energies, ionization-induced structural changes, and photoelectron spectra.
Topics: Adenine; Computational Biology; Cytosine; Electrons; Guanine; Mass Spectrometry; Models, Chemical; Nucleic Acids; Photochemistry; Thymine | 2010 |
The hydrolysis of striatal adenine- and guanine-based purines in a 6-hydroxydopamine rat model of Parkinson's disease.
Topics: 5'-Nucleotidase; Acid Anhydride Hydrolases; Adenine; Adrenergic Agents; Animals; Corpus Striatum; Disease Models, Animal; Guanine; Isoenzymes; Male; Medial Forebrain Bundle; Oxidopamine; Parkinson Disease; Phosphates; Rats; Rats, Wistar | 2011 |
Novel electrochemical sensor based on functionalized graphene for simultaneous determination of adenine and guanine in DNA.
Topics: Adenine; Adsorption; Biosensing Techniques; Carbon; DNA; DNA, Single-Stranded; Electrochemistry; Electrodes; Graphite; Guanine; Hot Temperature; Oxygen; Spectroscopy, Fourier Transform Infrared | 2011 |
Thermodynamic contributions of single internal rA·dA, rC·dC, rG·dG and rU·dT mismatches in RNA/DNA duplexes.
Topics: Adenine; Base Pair Mismatch; Cytosine; DNA; Guanine; RNA; Thermodynamics; Thymine; Uracil | 2011 |
Nanobiotechnology: sequencing at the end of the tunnel.
Topics: Adenine; Cytosine; DNA; Electrochemical Techniques; Electron Transport; Guanine; Microscopy, Scanning Tunneling; Nanotechnology; Sequence Analysis, DNA; Thymine | 2010 |
Entecavir as treatment for reactivation of hepatitis B in immunosuppressed patients.
Topics: Adenine; Aged; Antiviral Agents; Drug Therapy, Combination; Female; Guanine; Hepatitis B; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Immunocompromised Host; Immunosuppressive Agents; Male; Middle Aged; Organophosphonates; Retrospective Studies; Tenofovir; Treatment Outcome | 2010 |
[Analogs combination therapy in chronic hepatitis B: when and how?].
Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine | 2010 |
[Long-term therapy for chronic hepatitis B in HIV co-infected patients].
Topics: Adenine; Antiretroviral Therapy, Highly Active; Antiviral Agents; Deoxycytidine; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine; Guanine; Hepatitis B, Chronic; HIV Infections; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Recombinant Proteins; Telbivudine; Tenofovir; Thymidine | 2010 |
[Treatment has a positive impact on the long-term evolution of chronic hepatitis B].
Topics: Adenine; Antiviral Agents; Carcinoma, Hepatocellular; Clinical Trials as Topic; Guanine; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Liver Cirrhosis; Liver Neoplasms; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Tenofovir | 2010 |
Relaxation mechanisms of UV-photoexcited DNA and RNA nucleobases.
Topics: Adenine; Cytosine; DNA; Guanine; Models, Chemical; Molecular Dynamics Simulation; Molecular Structure; Photochemistry; RNA; Thymine; Ultraviolet Rays; Uracil | 2010 |
Single nucleotide polymorphisms of pattern recognition receptors and chronic periodontitis.
Topics: Adenine; Chronic Periodontitis; Cytosine; Dental Plaque Index; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Guanine; Homozygote; Humans; Lipopolysaccharide Receptors; Male; Middle Aged; Periodontal Attachment Loss; Periodontal Index; Periodontal Pocket; Polymorphism, Single Nucleotide; Smoking; Thymine; Toll-Like Receptor 2; Toll-Like Receptor 4; Toll-Like Receptor 9; Toll-Like Receptors | 2011 |
Profile of HBV antiviral resistance mutations with distinct evolutionary pathways against nucleoside/nucleotide analogue treatment among Chinese chronic hepatitis B patients.
Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; China; Cross-Sectional Studies; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Molecular Typing; Mutation, Missense; Nucleosides; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Thymidine; Young Adult | 2010 |
Evolution and suppression of HBV strains with multidrug resistance to lamivudine, adefovir dipivoxil and entecavir in a patient with chronic hepatitis B.
Topics: Adenine; Adult; Antiviral Agents; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; Evolution, Molecular; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Male; Organophosphonates; Phylogeny; Recombinant Proteins; Reverse Transcriptase Inhibitors; Time Factors; Treatment Outcome | 2010 |
Prevention of lamivudine-resistant hepatitis B recurrence after liver transplantation with entecavir plus tenofovir combination therapy and perioperative hepatitis B immunoglobulin only.
Topics: Adenine; Antiviral Agents; Combined Modality Therapy; Drug Resistance, Viral; Guanine; Hepatitis B; Hepatitis B virus; Humans; Immunization, Passive; Immunoglobulins; Lamivudine; Liver Transplantation; Male; Middle Aged; Organophosphonates; Perioperative Care; Secondary Prevention; Tenofovir; Treatment Outcome | 2011 |
Treatment of HBeAg-negative chronic hepatitis B patients with nucleos(t)ide analogues.
Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Time Factors; Treatment Outcome | 2011 |
Hyperlipidemic acute pancreatitis: a possible role of antiretroviral therapy with entecavir.
Topics: Abdominal Pain; Acute Disease; Adenine; Adult; Alcoholism; Antiretroviral Therapy, Highly Active; Critical Care; Diabetes Mellitus, Type 2; Fever; Guanine; Hepatitis B, Chronic; Humans; Hyperlipidemias; Hypertriglyceridemia; Male; Organophosphonates; Pancreatitis; Plasmapheresis; Reverse Transcriptase Inhibitors; Tenofovir; Tomography, X-Ray Computed; Triglycerides | 2011 |
Add-on adefovir is superior to a switch to entecavir as rescue therapy for Lamivudine-resistant chronic hepatitis B.
Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Retrospective Studies; Reverse Transcriptase Inhibitors; Treatment Outcome; Viral Load | 2011 |
Determination of the nucleosides and nucleobases in Tuber samples by dispersive solid-phase extraction combined with liquid chromatography-mass spectrometry.
Topics: Adenine; Adenosine; Agaricales; Chromatography, High Pressure Liquid; Chromatography, Liquid; Fermentation; Guanine; Guanosine; Hypoxanthine; Inosine; Mass Spectrometry; Nucleosides; Plant Extracts; Plant Tubers; Solid Phase Extraction; Tandem Mass Spectrometry; Uridine | 2011 |
Specific and nonspecific metal ion-nucleotide interactions at aqueous/solid interfaces functionalized with adenine, thymine, guanine, and cytosine oligomers.
Topics: Adenine; Cytosine; Guanine; Ions; Magnesium; Nucleotides; Thermodynamics; Thymine; Water | 2011 |
Simultaneous detection of guanine, adenine, thymine and cytosine at choline monolayer supported multiwalled carbon nanotubes film.
Topics: Adenine; Animals; Choline; Cytosine; DNA; Electrochemical Techniques; Fishes; Guanine; Nanotubes, Carbon; Oxidation-Reduction; Reproducibility of Results; Sensitivity and Specificity; Thymine | 2011 |
TGF-β1 gene polymorphism in renal transplant patients with and without gingival overgrowth.
Topics: Adenine; Adolescent; Adult; Aged; Arginine; Case-Control Studies; Codon; Cyclosporine; Cytosine; Female; Gene Frequency; Genotype; Gingival Overgrowth; Guanine; Haplotypes; Humans; Immunosuppressive Agents; Kidney Transplantation; Leucine; Male; Middle Aged; Polymorphism, Single Nucleotide; Proline; Promoter Regions, Genetic; Thymine; Transforming Growth Factor beta1; Young Adult | 2011 |
[Efficacy of entecavir and adefovir combination therapy in patients with chronic hepatitis B refractory to lamivudine and adefovir combination therapy].
Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates | 2011 |
[Efficacy and treatment strategy for drug resistances of nucleos(t)ide analogues for chronic hepatitis B].
Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Guanine; Hepatitis B, Chronic; Humans; Organophosphonates; Tenofovir | 2011 |
Interleukin-10 genotypes of the -1087 single nucleotide polymorphism influence sp1 expression in periodontitis lesions.
Topics: Adenine; Adult; Aged; Alveolar Bone Loss; B-Lymphocytes; Chronic Periodontitis; Female; Genotype; Gingiva; Gingival Hemorrhage; Guanine; Humans; Immunohistochemistry; Interleukin-10; Male; Middle Aged; Periodontal Pocket; Polymorphism, Single Nucleotide; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sp1 Transcription Factor; Up-Regulation | 2011 |
Comparison of multiplex restriction fragment mass polymorphism and sequencing analyses for detecting entecavir resistance in chronic hepatitis B.
Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Genotype; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Mass Spectrometry; Mutation; Organophosphonates; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Sequence Analysis, DNA; Viral Load | 2011 |
Splicing defects in the CFTR gene: minigene analysis of two mutations, 1811+1G>C and 1898+3A>G.
Topics: Adenine; Alternative Splicing; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Cytosine; Guanine; Heterozygote; Humans; Introns; Mutagenesis, Site-Directed; Mutation; Phenotype; RNA Precursors; RNA Splicing | 2011 |
Medication nonadherence with long-term management of patients with hepatitis B e antigen-negative chronic hepatitis B.
Topics: Adenine; Adult; Antiviral Agents; Asian People; Cohort Studies; Community Health Services; Drug Resistance, Viral; Female; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Male; Medication Adherence; Middle Aged; Organophosphonates; Treatment Outcome; Viral Load | 2011 |
FcγRIIB polymorphisms, periodontitis and preterm birth in Japanese pregnant women.
Topics: Adenine; Adult; Antibodies, Bacterial; Case-Control Studies; Cytosine; Exons; Female; Gestational Age; Guanine; Haplotypes; Heterozygote; Humans; Immunoglobulin G; Introns; Linkage Disequilibrium; Periodontal Attachment Loss; Periodontal Pocket; Periodontitis; Polymorphism, Single Nucleotide; Porphyromonas gingivalis; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Premature Birth; Receptors, IgG; Term Birth; Young Adult | 2011 |
Managing hepatitis B/HIV co-infected: adding entecavir to truvada (tenofovir disoproxil/emtricitabine) experienced patients.
Topics: Adenine; Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Deoxycytidine; DNA, Viral; Drug Administration Schedule; Drug Therapy, Combination; Emtricitabine; Guanine; Hepatitis B virus; Hepatitis B, Chronic; HIV Infections; Humans; Male; Middle Aged; Organophosphonates; Prospective Studies; Tenofovir; Treatment Outcome | 2011 |
Quantum-chemical study of interactions of trans-resveratrol with guanine-thymine dinucleotide and DNA-nucleobases.
Topics: Adenine; Antineoplastic Agents, Phytogenic; Cytosine; DNA; DNA Breaks; Guanine; Humans; Hydrogen Bonding; Models, Molecular; Neoplasms; Nucleic Acid Conformation; Quantum Theory; Resveratrol; Static Electricity; Stilbenes; Thermodynamics; Thymine; Vacuum; Water | 2011 |
Proper antiviral therapy for hepatitis B virus-associated acute-on-chronic liver failure.
Topics: Adenine; Antiviral Agents; End Stage Liver Disease; Guanine; Hepatitis B, Chronic; Humans; Liver Failure, Acute; Organophosphonates; Tenofovir | 2011 |
Consequence of one-electron oxidation and one-electron reduction for aniline.
Topics: Adenine; Aniline Compounds; Chemistry, Organic; Cytosine; Electrons; Guanine; Imines; Isomerism; Molecular Mimicry; Molecular Structure; Oxidation-Reduction; Quantum Theory; Thermodynamics | 2011 |
Sequence-independent and rapid long-range charge transfer through DNA.
Topics: Adenine; Base Pairing; Base Sequence; Cytosine; DNA; Guanine; Nanotechnology; Quantum Theory; Thymine | 2009 |
Genotypic resistance profile of hepatitis B virus (HBV) in a large cohort of nucleos(t)ide analogue-experienced Chinese patients with chronic HBV infection.
Topics: Adenine; Adult; Amino Acid Substitution; Antiviral Agents; China; DNA, Viral; Drug Resistance, Viral; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Molecular Sequence Data; Mutation, Missense; Nucleosides; Organophosphonates; Pyrimidinones; RNA-Directed DNA Polymerase; Sequence Analysis, DNA; Telbivudine; Thymidine; Viral Proteins | 2011 |
Density functional theory studies of the extent of hole delocalization in one-electron oxidized adenine and guanine base stacks.
Topics: Adenine; Electrons; Guanine; Oxidation-Reduction; Quantum Theory | 2011 |
Ionic liquid-functionalized graphene as modifier for electrochemical and electrocatalytic improvement: comparison of different carbon electrodes.
Topics: Adenine; Carbon; Catalysis; DNA; Electrochemical Techniques; Electrodes; Graphite; Guanine; Ionic Liquids; Limit of Detection; Mutation; Oxidation-Reduction | 2011 |
Electrocatalytic oxidation of nucleobases by TiO2 nanobelts.
Topics: Adenine; Catalysis; Cytosine; Electrochemical Techniques; Electrodes; Guanine; Nanotubes; Nucleosides; Oxidation-Reduction; Thymine; Titanium; Uracil | 2011 |
Analysis of plasma calprotectin and polymorphisms of S100A8 in patients with aggressive periodontitis.
Topics: Adenine; Adult; Aggressive Periodontitis; Calgranulin A; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Guanine; Humans; Inflammation Mediators; Leukocyte Count; Leukocyte L1 Antigen Complex; Male; Neutrophils; Periodontal Attachment Loss; Periodontal Pocket; Polymorphism, Genetic; Sex Factors | 2011 |
Association between recurrent aphthous stomatitis and inheritance of a single-nucleotide polymorphism of the NOS2 gene encoding inducible nitric oxide synthase.
Topics: 5' Untranslated Regions; Adenine; Adult; Case-Control Studies; Cytosine; Ethnicity; Exons; Female; Gene Expression Regulation, Enzymologic; Gene Frequency; Genotype; Guanine; Haplotypes; Humans; Jordan; Linkage Disequilibrium; Male; Nitric Oxide Synthase Type II; Polymorphism, Single Nucleotide; Recurrence; Stomatitis, Aphthous; Thymine | 2011 |
Association of matrix metalloproteinase (MMP-1, MMP-3 and MMP-9) and cyclooxygenase-2 gene polymorphisms and their proteins with chronic periodontitis.
Topics: Adenine; Adult; Alleles; Biomarkers; Chronic Periodontitis; Cyclooxygenase 2; Cytosine; Female; Genotype; Guanine; Heterozygote; Homozygote; Humans; Inflammation Mediators; Male; Matrix Metalloproteinase 1; Matrix Metalloproteinase 3; Matrix Metalloproteinase 9; Middle Aged; Periodontal Attachment Loss; Periodontal Pocket; Polymorphism, Single Nucleotide; Vascular Endothelial Growth Factor A; Young Adult | 2011 |
Investigating purine-functionalised carbon nanotubes and their properties: a computational approach.
Topics: Adenine; Chemical Phenomena; Computer Simulation; Guanine; Models, Molecular; Nanotubes, Carbon | 2011 |
Interaction between tumour necrosis factor-α gene polymorphisms and substance use on risk of betel quid-related oral and pharyngeal squamous cell carcinoma in Taiwan.
Topics: Adenine; Adult; Aged; Alcohol Drinking; Alleles; Areca; Carcinoma, Squamous Cell; Case-Control Studies; Chromosome Mapping; Ethnicity; Genetic Predisposition to Disease; Genetic Variation; Genotype; Guanine; Humans; Male; Middle Aged; Mouth Neoplasms; Neoplasm Recurrence, Local; Neoplasm Staging; Pharyngeal Neoplasms; Polymorphism, Single Nucleotide; Prognosis; Risk Factors; Smoking; Survival Rate; Taiwan; Tumor Necrosis Factor-alpha | 2011 |
Point mutations in human guanylate kinase account for acquired resistance to anticancer nucleotide analogue PMEG.
Topics: Adenine; Adenylate Kinase; Amino Acid Sequence; Antineoplastic Agents; Cells, Cultured; Drug Resistance, Neoplasm; Guanine; Guanylate Kinases; Humans; Molecular Sequence Data; Organophosphorus Compounds; Phosphorylation; Point Mutation | 2011 |
Porphyromonas gingivalis mutY is involved in the repair of oxidative stress-induced DNA mispairing.
Topics: Adenine; Bacteriological Techniques; Base Pair Mismatch; Base Sequence; Conserved Sequence; DNA Damage; DNA Glycosylases; DNA Mismatch Repair; Glutamine; Guanine; Humans; Hydrogen Peroxide; Mutagenesis, Insertional; Mutagenesis, Site-Directed; Mutation; Oxidants; Oxidative Stress; Plasmids; Porphyromonas gingivalis; Reverse Transcriptase Polymerase Chain Reaction; Valine | 2011 |
Interactions between Al₁₂X (X = Al, C, N and P) nanoparticles and DNA nucleobases/base pairs: implications for nanotoxicity.
Topics: Adenine; Aluminum; Carbohydrate Conformation; Carbon; Cytosine; DNA; DNA Damage; Guanine; Models, Molecular; Nanoparticles; Nitrogen; Phosphates; Static Electricity; Thymine | 2012 |
Anhydrous crystals of DNA bases are wide gap semiconductors.
Topics: Adenine; Crystallization; Cytosine; DNA; Guanine; Models, Molecular; Semiconductors; Thymine; Water | 2011 |
Two patterns of alanine aminotransferase increase to predict long-term viral response in chronic hepatitis B patients: virus- or host-induced?
Topics: Adenine; Adult; Aged; Alanine Transaminase; Antiviral Agents; DNA, Viral; Female; Guanine; Hepacivirus; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interferon-gamma; Lamivudine; Male; Middle Aged; Nucleosides; Organophosphonates; Predictive Value of Tests; Pyrimidinones; T-Lymphocytes; Telbivudine; Thymidine; Treatment Outcome; Up-Regulation; Young Adult | 2011 |
Adenine and guanine recognition of stop codon is mediated by different N domain conformations of translation termination factor eRF1.
Topics: Adenine; Codon, Terminator; Guanine; Humans; Models, Molecular; Peptide Chain Termination, Translational; Peptide Termination Factors; Protein Binding; Protein Structure, Tertiary; Ribosomal Proteins; RNA, Messenger | 2011 |
Molecular electrostatic potentials of DNA base-base pairing and mispairing.
Topics: Adenine; Base Pair Mismatch; Base Pairing; Cytosine; DNA; Guanine; Hydrogen Bonding; Models, Chemical; Models, Molecular; Static Electricity; Thermodynamics; Thymine | 2012 |
Mechanism of epoxide hydrolysis in microsolvated nucleotide bases adenine, guanine and cytosine: a DFT study.
Topics: Adenine; Cytosine; Epoxy Compounds; Guanine; Hydrogen Bonding; Hydrolysis; Nucleotides; Quantum Theory; Water | 2011 |
Adsorption of DNA/RNA nucleobases on hexagonal boron nitride sheet: an ab initio study.
Topics: Adenine; Adsorption; Boron Compounds; Cytosine; Guanine; Models, Molecular; Thymine; Uracil | 2011 |
Predictors of relapse in chronic hepatitis B after discontinuation of anti-viral therapy.
Topics: Adenine; Adult; Antiviral Agents; Female; Guanine; Hepatitis B Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Proportional Hazards Models; Real-Time Polymerase Chain Reaction; Recurrence; Time Factors | 2011 |
Successful switch to tenofovir after suboptimal response to entecavir in an immunocompromised patient with chronic hepatitis B and without genotypic hepatitis B virus resistance.
Topics: Adenine; Adult; Alanine Transaminase; Antiviral Agents; Bone Marrow; DNA, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Immunocompromised Host; Italy; Organophosphonates; Tenofovir; Treatment Outcome; Viremia | 2011 |
The human caveolin 1 gene upstream purine complex and neurodegeneration--a common signature.
Topics: Adenine; Case-Control Studies; Caveolin 1; Guanine; Haplotypes; Humans; Multiple Sclerosis; Neurodegenerative Diseases; Polymorphism, Single Nucleotide; Purines | 2011 |
Association between mutation spectra and stable and unstable DNA adduct profiles in Salmonella for benzo[a]pyrene and dibenzo[a,l]pyrene.
Topics: Adenine; Benzo(a)pyrene; Benzopyrenes; DNA Adducts; Guanine; Mutagenicity Tests; Mutagens; Mutation; Salmonella | 2011 |
Large-scale survey of naturally occurring HBV polymerase mutations associated with anti-HBV drug resistance in untreated patients with chronic hepatitis B.
Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Female; Gene Products, pol; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-alpha; Male; Middle Aged; Mutation; Organophosphonates; Polyethylene Glycols; Recombinant Proteins | 2011 |
Unsuccessful therapy with adefovir and entecavir-tenofovir in a patient with chronic hepatitis B infection with previous resistance to lamivudine: a fourteen-year evolution of hepatitis B virus mutations.
Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Evolution, Molecular; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Middle Aged; Mutation; Organophosphonates; Tenofovir; Treatment Failure | 2011 |
Which one among the Pt-containing anticancer drugs more easily forms monoadducts with G and A DNA bases? A comparative study among oxaliplatin, nedaplatin, and carboplatin.
Topics: Adenine; Antineoplastic Agents; Carboplatin; DNA Adducts; Guanine; Hydrogen-Ion Concentration; Models, Molecular; Organoplatinum Compounds; Oxaliplatin; Quantum Theory; Thermodynamics | 2011 |
Rapid evaluation of the binding energies between peptide amide and DNA base.
Topics: Adenine; Amides; Cytosine; Dimerization; DNA; Guanine; Hydrogen Bonding; Models, Molecular; Peptides; Protein Binding; Thermodynamics; Thymine | 2011 |
NAT2 slow acetylation haplotypes are associated with the increased risk of betel quid-related oral and pharyngeal squamous cell carcinoma.
Topics: Acetylation; Adenine; Adult; Age Factors; Alcohol Drinking; Areca; Arylamine N-Acetyltransferase; Carcinoma, Squamous Cell; Case-Control Studies; Cytosine; Gene Frequency; Genetic Markers; Genotype; Guanine; Haplotypes; Humans; Linkage Disequilibrium; Male; Middle Aged; Mouth Neoplasms; Pharyngeal Neoplasms; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Risk Factors; Smoking; Thymine | 2011 |
Rapid cell division contributes to efficient induction of A/T mutations during Ig gene hypermutation.
Topics: Adenine; B-Lymphocytes; Cell Division; Cell Line; Cytidine Deaminase; DNA Mismatch Repair; Germinal Center; Guanine; Humans; Mutation; Reverse Transcriptase Polymerase Chain Reaction; Somatic Hypermutation, Immunoglobulin; Thymine; Uracil | 2011 |
Functional splicing assay of DSPP mutations in hereditary dentin defects.
Topics: Adenine; Codon, Nonsense; Conserved Sequence; Cytosine; Dentin Dysplasia; Dentinogenesis Imperfecta; DNA Mutational Analysis; Exons; Extracellular Matrix Proteins; Genotype; Guanine; Humans; Isoleucine; Mutagenesis; Mutation; Mutation, Missense; Phenotype; Phosphoproteins; Polymerase Chain Reaction; Proline; RNA Splice Sites; RNA Splicing; Sialoglycoproteins; Thymine; Valine | 2011 |
Serum HBsAg decline during long-term potent nucleos(t)ide analogue therapy for chronic hepatitis B and prediction of HBsAg loss.
Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Female; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Male; Organophosphonates; Tenofovir | 2011 |
Antiviral drug resistance testing in patients with chronic hepatitis B.
Topics: Adenine; Adult; Antiviral Agents; Data Collection; Decision Making; DNA, Viral; Drug Resistance, Viral; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Mutation; Organophosphonates; Retrospective Studies; Surveys and Questionnaires; Tenofovir; Treatment Outcome; Viral Load | 2012 |
2'-O,4'-C-methyleneoxymethylene bridged nucleic acids (2',4'-BNA(COC)).
Topics: 5-Methylcytosine; Adenine; Biological Products; Bridged-Ring Compounds; Chemistry, Pharmaceutical; Cytosine; DNA; Guanine; Nucleosides; Oligonucleotides; Oligonucleotides, Antisense; Organophosphorus Compounds; RNA; Thymine | 2011 |
Late onset of hepatitis B virus reactivation following hematopoietic stem cell transplantation: successful treatment with combined entecavir plus tenofovir therapy.
Topics: Adenine; Age of Onset; Antiviral Agents; Drug Therapy, Combination; Female; Guanine; Hematopoietic Stem Cell Transplantation; Hepatitis B; Hepatitis B virus; Humans; Middle Aged; Organophosphonates; Tenofovir; Transplantation, Homologous; Treatment Outcome; Virus Activation | 2012 |
Design, synthesis, and biological evaluation of triazolo-pyrimidine derivatives as novel inhibitors of hepatitis B virus surface antigen (HBsAg) secretion.
Topics: Adenine; Animals; Antiviral Agents; Biological Availability; Drug Design; Drug Resistance, Viral; Guanine; Hep G2 Cells; Hepatitis B; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Lamivudine; Male; Mice; Models, Chemical; Molecular Structure; Mutation; Organophosphonates; Pyrimidines; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Tenofovir; Tetrazoles | 2011 |
[Improvement of health-related quality of life in chronic hepatitis B patients treated with entecavir or adefovir].
Topics: Adenine; Adult; Aged; Antiviral Agents; Guanine; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates; Quality of Life; Young Adult | 2011 |
The efficacy of entecavir therapy in chronic hepatitis B patients with suboptimal response to adevofir.
Topics: Adenine; Adult; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Female; Follow-Up Studies; Guanine; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates; Regression Analysis; Time Factors; Treatment Outcome; Viral Load | 2011 |
Management options for lamivudine-resistant chronic hepatitis B patients with suboptimal virological suppression by adefovir.
Topics: Adenine; Adult; Antiviral Agents; Cohort Studies; DNA, Viral; Drug Resistance, Viral; Female; Follow-Up Studies; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Retrospective Studies; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Outcome | 2011 |
An electrochemical sensor based on single-stranded DNA-poly(sulfosalicylic acid) composite film for simultaneous determination of adenine, guanine, and thymine.
Topics: Adenine; Animals; Benzenesulfonates; Biosensing Techniques; Carbon; Dielectric Spectroscopy; DNA; DNA, Single-Stranded; Electricity; Electrochemical Techniques; Electrodes; Glass; Guanine; Microscopy, Electron, Scanning; Polymers; Reproducibility of Results; Salicylates; Thymine | 2011 |
Association of the FcγRIIB-nt645+25A/G polymorphism with the expression level of the FcγRIIb receptor, the antibody response to Porphyromonas gingivalis and the severity of periodontitis.
Topics: Adenine; Adult; Alveolar Bone Loss; Antibodies, Bacterial; Antigens, Bacterial; B-Lymphocytes; Bacterial Outer Membrane Proteins; Chronic Periodontitis; Female; Genotype; Guanine; Humans; Immunoglobulin G; Introns; Male; Middle Aged; Periodontal Attachment Loss; Periodontal Pocket; Polymerase Chain Reaction; Polymorphism, Genetic; Porphyromonas gingivalis; Receptors, IgG; Sequence Analysis, DNA | 2012 |
Long-term efficacy of entecavir therapy in chronic hepatitis B patients with antiviral resistance to lamivudine and adefovir.
Topics: Adenine; Adult; Aged; Alanine Transaminase; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver Function Tests; Male; Middle Aged; Organophosphonates; Retrospective Studies; Treatment Outcome; Viral Load | 2011 |
Long-term efficacy of entecavir in adefovir-refractory chronic hepatitis B patients with prior lamivudine resistance.
Topics: Adenine; Adult; Aged; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Female; Guanine; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Salvage Therapy; Treatment Outcome | 2011 |
Tandem GA residues on opposite sides of the loop in molecular beacon-like DNA hairpins compact the loop and increase hairpin stability.
Topics: Adenine; Base Sequence; Electrolytes; Guanine; Hot Temperature; Microsatellite Repeats; Nucleic Acid Conformation; Nucleic Acid Denaturation; Solutions | 2011 |
Supramolecular nanofibers and hydrogels of nucleopeptides.
Topics: Adenine; Biocompatible Materials; Circular Dichroism; Cytosine; Deoxyadenosines; Dipeptides; Guanine; HeLa Cells; Humans; Hydrogels; Molecular Structure; Nanofibers; Nucleoproteins; Peptides; Rheology; Thymine | 2011 |
RNA oxidation adducts 8-OHG and 8-OHA change with Aβ42 levels in late-stage Alzheimer's disease.
Topics: Adenine; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Brain; Case-Control Studies; DNA Damage; Enzyme-Linked Immunosorbent Assay; Female; Gas Chromatography-Mass Spectrometry; Guanine; Humans; Male; Neurofibrillary Tangles; Oxidation-Reduction; Plaque, Amyloid; RNA | 2011 |
Chemically-modified graphenes for oxidation of DNA bases: analytical parameters.
Topics: Adenine; Cytosine; DNA; Electrochemistry; Graphite; Guanine; Models, Molecular; Molecular Conformation; Oxidation-Reduction; Oxygen; Thymine | 2011 |
Design and synthesis of carbocyclic versions of furanoid nucleoside phosphonic Acid analogues as potential anti-hiv agents.
Topics: Adenine; Anti-HIV Agents; Cell Line; Drug Design; Furans; Guanine; HIV-1; Humans; Molecular Structure; Organophosphonates | 2011 |
CE analysis and molecular characterisation of depurinated DNA samples.
Topics: Adenine; Biochemical Phenomena; DNA; DNA Damage; Electrophoresis, Agar Gel; Electrophoresis, Capillary; Guanine; Humans; Linear Models; Male; Microsatellite Repeats; Middle Aged; Molecular Weight; Nucleic Acid Conformation; Polymerase Chain Reaction | 2011 |
Intermolecular band dispersion in quasi-one-dimensional adenine assemblies.
Topics: Adenine; Electrons; Graphite; Guanine; Photoelectron Spectroscopy; Quantum Theory | 2011 |
Adefovir-based combination therapy with entecavir or lamivudine for patients with entecavir-refractory chronic hepatitis B.
Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Treatment Outcome; Viral Load | 2012 |
Entecavir plus tenofovir combination as rescue therapy in pre-treated chronic hepatitis B patients: an international multicenter cohort study.
Topics: Adenine; Adult; Aged; Antiviral Agents; Cohort Studies; Drug Resistance, Viral; Drug Therapy, Combination; Female; Follow-Up Studies; Guanine; Hepatitis B, Chronic; Humans; Internationality; Male; Middle Aged; Organophosphonates; Retrospective Studies; Tenofovir; Treatment Outcome; Viremia; Young Adult | 2012 |
Canadian patients with chronic hepatitis B cannot access appropriate drug treatments: a call for change.
Topics: Adenine; Antiviral Agents; Canada; Drug Approval; Guanine; Health Services Accessibility; Hepatitis B, Chronic; Humans; Insurance Coverage; Lamivudine; Liver Cirrhosis; National Health Programs; Organophosphonates; Tenofovir | 2011 |
Association of interleukin-10 gene promoter polymorphisms with chronic and aggressive periodontitis.
Topics: Adenine; Adolescent; Adult; Aggressive Periodontitis; Alleles; Chronic Periodontitis; Cytosine; Female; Gene Frequency; Genetic Markers; Genotype; Guanine; Humans; Interleukin-10; Male; Middle Aged; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Risk Factors | 2012 |
Molecular characterization of a novel entecavir mutation pattern isolated from a multi-drug refractory patient with chronic hepatitis B infection.
Topics: Adenine; Adult; Antiviral Agents; Cell Line, Tumor; Drug Resistance, Multiple, Viral; Fatal Outcome; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Microbial Sensitivity Tests; Mutation; Organophosphonates; Virus Replication | 2012 |
Tenofovir plus entecavir as rescue therapy for multidrug-resistant chronic hepatitis B.
Topics: Adenine; Adult; Antiviral Agents; Drug Resistance, Multiple, Viral; Drug Substitution; Drug Therapy, Combination; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Mutation; Organophosphonates; Tenofovir; Treatment Outcome; Viral Load; Virus Replication | 2012 |
Potent hepatitis B surface antigen response to treatment of hepatitis-B-e-antigen-positive chronic hepatitis B with α-interferon plus a nucleos(t)ide analog.
Topics: Adenine; Adolescent; Adult; Antiviral Agents; Child; Child, Preschool; Drug Therapy, Combination; Female; Follow-Up Studies; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Male; Middle Aged; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Retrospective Studies; Time Factors; Young Adult | 2012 |
Thymine dimer photoreversal in purine-containing trinucleotides.
Topics: Adenine; Guanine; Isomerism; Purines; Pyrimidine Dimers; Quantum Theory; Spectrophotometry, Ultraviolet | 2012 |
Association analysis between the -2518MCP-1(A/G) polymorphism and generalized aggressive periodontitis in a Chinese population.
Topics: Adenine; Adult; Aggressive Periodontitis; Case-Control Studies; Chemokine CCL2; China; Cohort Studies; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Guanine; Humans; Male; Periodontal Attachment Loss; Periodontal Pocket; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Risk Factors; Sex Factors; Smoking | 2012 |
Theoretical study of the adsorption of DNA bases on the acidic external surface of montmorillonite.
Topics: Adenine; Adsorption; Bentonite; Cytosine; Guanine; Hydrogen Bonding; Models, Theoretical; Protons; Static Electricity; Surface Properties; Thermodynamics | 2012 |
Efficacy of entecavir and adefovir combination therapy for patients with lamivudine- and entecavir-resistant chronic hepatitis B.
Topics: Adenine; Adult; Aged; Antiviral Agents; DNA, Viral; Drug Monitoring; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver Function Tests; Male; Middle Aged; Organophosphonates; Treatment Outcome; Viral Load; Virus Replication | 2012 |
Number of graphene layers exhibiting an influence on oxidation of DNA bases: analytical parameters.
Topics: Adenine; Biosensing Techniques; DNA; Electrochemistry; Electrodes; Graphite; Guanine; Oxidation-Reduction | 2012 |
Protection of riboflavin and UVB sensitized degradation of DNA and RNA bases by natural antioxidants.
Topics: Adenine; Antioxidants; Ascorbic Acid; Cytosine; DNA; DNA Damage; Glutathione; Guanine; Nucleic Acids; Oxidative Stress; Photolysis; Protective Agents; Purines; Pyrimidines; Riboflavin; RNA; Thymine; Ultraviolet Rays; Uracil | 2012 |
MBL2, MASP2, AMELX, and ENAM gene polymorphisms and dental caries in Polish children.
Topics: Adenine; Adolescent; Alleles; Amelogenin; Case-Control Studies; Child, Preschool; Cytosine; Dental Caries; DMF Index; Extracellular Matrix Proteins; Female; Gene Frequency; Genome, Human; Guanine; Haplotypes; Heterozygote; Humans; Male; Mannose-Binding Lectin; Mannose-Binding Protein-Associated Serine Proteases; Mutation; Poland; Polymorphism, Single Nucleotide; Proteins; Thymine | 2012 |
Antiviral efficacy of combination therapy with entecavir and adefovir for entecavir/lamivudine-resistant hepatitis B virus with or without adefovir resistance.
Topics: Adenine; Adult; Aged; Antiviral Agents; DNA, Viral; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Treatment Outcome; Viral Load | 2012 |
Predominance of G to A codon 12 mutation K-ras gene in Dukes' B colorectal cancer.
Topics: Adenine; Adenoma; Adult; Aged; Aged, 80 and over; Aspartic Acid; Carcinoma; Codon; Colorectal Neoplasms; Exons; Female; Genes, ras; Glycine; Guanine; Humans; Male; Middle Aged; Mutation; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational | 2012 |
Transarterial chemoembolization for hepatitis B virus-associated hepatocellular carcinoma: improved survival after concomitant treatment with nucleoside analogues.
Topics: Adenine; Adult; Aged; Aged, 80 and over; Antiviral Agents; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Chi-Square Distribution; Disease-Free Survival; Female; Guanine; Hepatitis B, Chronic; Humans; Japan; Kaplan-Meier Estimate; Lamivudine; Liver Neoplasms; Male; Middle Aged; Multivariate Analysis; Nucleosides; Organophosphonates; Proportional Hazards Models; Retrospective Studies; Risk Assessment; Risk Factors; Survival Rate; Time Factors; Treatment Outcome | 2012 |
A novel sensitive DNA-biosensor for detection of a carcinogen, Sudan II, using electrochemically treated pencil graphite electrode by voltammetric methods.
Topics: Adenine; Adsorption; Animals; Azo Compounds; Biosensing Techniques; Calibration; Carcinogens; DNA; Electrochemistry; Electrodes; Food Contamination; Graphite; Guanine; Hydrogen-Ion Concentration; Limit of Detection; Male; Oxidation-Reduction; Salmon; Solutions; Spermatozoa | 2012 |
Entecavir plus adefovir combination treatment for chronic hepatitis B patients after failure of nucleoside/nucleotide analogues.
Topics: Adenine; Adult; Antiviral Agents; Cohort Studies; DNA, Viral; Drug Combinations; Drug Resistance, Viral; Female; Genotype; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Treatment Failure; Viral Load | 2012 |
The removal of alkylation products from the DNA of Escherichia coli cells treated with the carcinogens N-ethyl-N-nitrosourea and N-methyl-N-nitrosourea: influence of growth conditions and DNA repair defects.
Topics: Adenine; Alkylating Agents; Alkylation; Carcinogens; DNA Repair; DNA, Bacterial; Escherichia coli; Ethylnitrosourea; Guanine; Methylation; Methylnitrosourea | 1980 |
In vitro reaction of the carcinogen, N-hydroxy-2-naphthylamine, with DNA at the C-8 and N2 atoms of guanine and at the N6 atom of adenine.
Topics: 2-Naphthylamine; Adenine; Animals; Carcinogens; DNA; DNA Adducts; Guanine; Hydrogen-Ion Concentration; Liver; Magnetic Resonance Spectroscopy; Mass Spectrometry; Rats; Spectrophotometry, Ultraviolet | 1980 |
Involvement of MAP kinases in the cytotoxicity of acyclic nucleoside phosphonates.
Topics: Adenine; Antineoplastic Agents; Caspase 3; Cell Line, Tumor; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Guanine; HL-60 Cells; Humans; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Organophosphorus Compounds; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-akt; RNA, Messenger | 2012 |
Genotype and haplotype analysis of WNT genes in non-syndromic cleft lip with or without cleft palate.
Topics: Adenine; Case-Control Studies; Chromosome Mapping; Cleft Lip; Cleft Palate; Cytosine; Epistasis, Genetic; Female; Gene Frequency; Genes, Recessive; Genetic Variation; Genotype; Guanine; Haplotypes; Homozygote; Humans; Male; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Proto-Oncogene Proteins; Real-Time Polymerase Chain Reaction; Risk Factors; Thymine; Wnt Proteins; Wnt Signaling Pathway; Wnt-5a Protein; Wnt3 Protein; Wnt3A Protein | 2012 |
Influence of epigenetic modifications of the interleukin-10 promoter on IL10 gene expression.
Topics: Acetylation; Adenine; Azacitidine; B-Lymphocytes; Cell Line; Chromatin; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; Epigenesis, Genetic; Escherichia coli; Gene Expression Regulation; Genotype; Guanine; Histone Deacetylase Inhibitors; Histones; Humans; Interleukin-10; Lipopolysaccharides; Methylation; Polymorphism, Genetic; Promoter Regions, Genetic; RNA, Messenger; Transcription, Genetic | 2012 |
High-resolution melting and real-time PCR for quantification and detection of drug-resistant HBV mutants in a single amplicon.
Topics: Adenine; Antiviral Agents; DNA, Complementary; DNA, Viral; Drug Resistance, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Molecular Diagnostic Techniques; Nucleic Acid Denaturation; Organophosphonates; Pilot Projects; Polymerase Chain Reaction; Viral Load | 2012 |
Survivin SNP-carcinogen interactions in oral cancer.
Topics: Adenine; Alcohol Drinking; Areca; Carcinogens, Environmental; Case-Control Studies; Cocarcinogenesis; Cysteine Proteinase Inhibitors; Cytosine; Gene Frequency; Gene-Environment Interaction; Genotype; Guanine; Haplotypes; Homozygote; Humans; Inhibitor of Apoptosis Proteins; Male; Middle Aged; Mouth Neoplasms; Neoplasm Proteins; Polymorphism, Single Nucleotide; Real-Time Polymerase Chain Reaction; Risk Factors; Smoking; Survivin; Taiwan; Thymine | 2012 |
Response to tenofovir monotherapy in chronic hepatitis B patients with prior suboptimal response to entecavir.
Topics: Adenine; Adult; Antiviral Agents; Cohort Studies; Female; Follow-Up Studies; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Medication Adherence; Middle Aged; Organophosphonates; Tenofovir; Treatment Outcome; Young Adult | 2012 |
Electrochemical sensor for guanine using a self-assembled monolayer of 1,8,15,22-tetraaminophthalocyanatonickel(II) on glassy carbon electrode.
Topics: Adenine; Biosensing Techniques; Carbon; Electrochemical Techniques; Electrodes; Glass; Guanine; Kinetics; Nickel; Organometallic Compounds; Oxidation-Reduction; Reproducibility of Results | 2012 |
New approach to analyze genetic and clinical data in bisphosphonate-induced osteonecrosis of the jaw.
Topics: Adenine; Administration, Intravenous; Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Aryl Hydrocarbon Hydroxylases; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone Density Conservation Agents; Breast Neoplasms; Calcium; Cytochrome P-450 CYP2C8; Diphosphonates; Estrogen Receptor Modulators; Female; Genotype; Guanine; Humans; Hungary; Lipids; Male; Mandibular Diseases; Maxillary Diseases; Middle Aged; Parathyroid Hormone; Polymorphism, Single Nucleotide; Principal Component Analysis; Recurrence; Time Factors; Vitamin D | 2012 |
Genetic variation and significant association of polymorphism rs7700944 G>A of TIM-4 gene with rheumatoid arthritis susceptibility in Chinese Han and Hui populations.
Topics: Adenine; Alleles; Arthritis, Rheumatoid; Asian People; Case-Control Studies; China; Ethnicity; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genetic Variation; Guanine; Humans; Introns; Male; Membrane Proteins; Odds Ratio; Polymorphism, Single Nucleotide; Risk Factors | 2012 |
The functional cytotoxic T lymphocyte-associated Protein 4 49G-to-A genetic variant and risk of pancreatic cancer.
Topics: Adenine; Age Factors; Aged; Alcohol Drinking; Asian People; Case-Control Studies; CTLA-4 Antigen; Diabetes Complications; Female; Gene-Environment Interaction; Genetic Predisposition to Disease; Genotype; Guanine; Humans; Logistic Models; Male; Middle Aged; Odds Ratio; Pancreatic Neoplasms; Polymorphism, Single Nucleotide; Risk Assessment; Risk Factors; Sex Factors; Smoking | 2012 |
Crystal structures of a type-1 ribosome inactivating protein from Momordica balsamina in the bound and unbound states.
Topics: Adenine; Adenosine Triphosphate; Amino Acid Sequence; Animals; Catalytic Domain; Conserved Sequence; Crystallography, X-Ray; Deoxyadenine Nucleotides; Guanine; Hydrobromic Acid; Models, Molecular; Molecular Sequence Data; Momordica; Plant Proteins; Protein Binding; Protein Structure, Secondary; Rats; Ribose; Ribosome Inactivating Proteins, Type 1; Ribosomes; RNA, Bacterial; RNA, Ribosomal; Structural Homology, Protein | 2012 |
[Hungarian consensus guideline for the diagnosis and treatment of B, C, and D viral hepatitis].
Topics: Adenine; Antiviral Agents; Comorbidity; Consensus; Drug Administration Schedule; Drug Therapy, Combination; Genotype; Guanine; Hepacivirus; Hepatitis B; Hepatitis C; Hepatitis D; Humans; Hungary; Interferon-alpha; Interferons; Lamivudine; Oligopeptides; Organophosphonates; Polyethylene Glycols; Proline; Recombinant Proteins; Ribavirin; RNA, Viral; Tenofovir; Time Factors; Treatment Outcome | 2012 |
Isoguanine formation from adenine.
Topics: Adenine; Guanine; Models, Molecular; Quantum Theory; Thermodynamics | 2012 |
Safety of long-term nucleos(t)ide treatment in chronic hepatitis B.
Topics: Adenine; Antiviral Agents; Drug Administration Schedule; Evidence-Based Medicine; Guanine; Hepatitis B, Chronic; Humans; Organophosphonates; Patient Safety; Risk Assessment; Risk Factors; Tenofovir; Time Factors; Treatment Outcome | 2012 |
Fabrication of a modified electrode based on Fe(3)O(4)NPs/MWCNT nanocomposite: application to simultaneous determination of guanine and adenine in DNA.
Topics: Adenine; Animals; Biosensing Techniques; Calibration; Dielectric Spectroscopy; DNA; Electrochemical Techniques; Electrodes; Ferric Compounds; Fishes; Guanine; Hydrogen-Ion Concentration; Limit of Detection; Magnetite Nanoparticles; Male; Microscopy, Atomic Force; Microscopy, Electron, Transmission; Nanocomposites; Nanotubes, Carbon; Oxidation-Reduction; Reproducibility of Results; Spermatozoa; Surface Properties | 2012 |
Genetic association study between Interleukin 10 gene and dental implant loss.
Topics: Adenine; Alleles; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Case-Control Studies; Cytosine; Dental Implants; Dental Restoration Failure; Female; Genetic Predisposition to Disease; Genotype; Guanine; Haplotypes; Humans; Hypertension; Interleukin-10; Linkage Disequilibrium; Male; Middle Aged; Osseointegration; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Rheumatic Diseases; Smoking; Thymine | 2012 |
Prediction of superovulatory response in Japanese Black cattle using ultrasound, plasma anti-Müllerian hormone concentrations and polymorphism in the ionotropic glutamate receptor AMPA1/GRIA1.
Topics: Adenine; Alleles; Animals; Anti-Mullerian Hormone; Cattle; Female; Fertilization; Gene Expression Regulation, Developmental; Genetic Markers; Guanine; Polymorphism, Single Nucleotide; Receptors, AMPA; Reproducibility of Results; Reproductive Techniques, Assisted; Superovulation | 2012 |
Lamivudine plus adefovir vs. entecavir in HBeAg-positive hepatitis B with sequential treatment failure of lamivudine and adefovir.
Topics: Adenine; Adult; Alanine Transaminase; Antiviral Agents; DNA, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Prognosis; Retrospective Studies; Treatment Failure | 2012 |
De novo pyrimidine nucleotide synthesis mainly occurs outside of plastids, but a previously undiscovered nucleobase importer provides substrates for the essential salvage pathway in Arabidopsis.
Topics: Adenine; Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Biosynthetic Pathways; Brassica; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Gene Expression Regulation, Plant; Green Fluorescent Proteins; Guanine; Intracellular Membranes; Models, Biological; Molecular Sequence Data; Nucleobase Transport Proteins; Nucleotides; Plastids; Protein Transport; Protoplasts; Pyrimidines; Recombinant Fusion Proteins; RNA, Messenger; Sequence Alignment; Sodium Chloride; Substrate Specificity; Symporters; Time Factors; Uracil | 2012 |
Influence of cytotoxic T lymphocyte antigen-4 (CTLA-4) gene polymorphisms in periodontitis.
Topics: Adenine; Adolescent; Adult; Aged; Aggressive Periodontitis; Alleles; Chronic Periodontitis; CTLA-4 Antigen; Cytosine; Dental Plaque Index; Exons; Female; Gene Frequency; Genetic Predisposition to Disease; Genetic Variation; Gingival Hemorrhage; Guanine; Heterozygote; Homozygote; Humans; Male; Middle Aged; Periodontal Attachment Loss; Periodontal Pocket; Polymorphism, Single Nucleotide; Risk Factors; Thymine; Young Adult | 2012 |
Similar risk of renal events among patients treated with tenofovir or entecavir for chronic hepatitis B.
Topics: Adenine; Adult; Aged; Antiviral Agents; Cohort Studies; Creatinine; Female; Glomerular Filtration Rate; Guanine; Hepatitis B, Chronic; Humans; Kidney Diseases; Male; Middle Aged; Organophosphonates; Retrospective Studies; Risk Assessment; Tenofovir; Young Adult | 2012 |
Antiviral therapy against chronic hepatitis B in Brazil: high rates of lamivudine resistance mutations and correlation with HBV genotypes.
Topics: Adenine; Adolescent; Adult; Aged; Antiviral Agents; Cross-Sectional Studies; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Tenofovir; Viral Load; Young Adult | 2012 |
High efficacy of adefovir and entecavir combination therapy in patients with nucleoside-refractory hepatitis B.
Topics: Adenine; Adult; Alanine Transaminase; Antiviral Agents; DNA, Viral; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; Female; Genotype; Guanine; Hepatitis B Antibodies; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Male; Middle Aged; Nucleosides; Organophosphonates | 2012 |
Genetic susceptibility to periapical disease: conditional contribution of MMP2 and MMP3 genes to the development of periapical lesions and healing response.
Topics: Adenine; Dental Caries; Dental Pulp Necrosis; Dentin; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Guanine; Haplotypes; Humans; Male; Matrix Metalloproteinase 13; Matrix Metalloproteinase 14; Matrix Metalloproteinase 2; Matrix Metalloproteinase 3; Matrix Metalloproteinase 9; Middle Aged; Periapical Periodontitis; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Protease Inhibitors; Thymine; Tissue Inhibitor of Metalloproteinase-2; Wound Healing | 2012 |
Role of pK(a) of nucleobases in the origins of chemical evolution.
Topics: Adenine; Base Pairing; Evolution, Chemical; Guanine; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kinetics; Nucleosides; Uracil; Water | 2012 |
Gas-phase studies of purine 3-methyladenine DNA glycosylase II (AlkA) substrates.
Topics: Adenine; Catalytic Domain; DNA Glycosylases; Escherichia coli; Guanine; Protons; Purines; Stereoisomerism; Substrate Specificity; Temperature; Xanthine | 2012 |
Crystal structure of human methyl-binding domain IV glycosylase bound to abasic DNA.
Topics: 5-Methylcytosine; Adenine; Binding Sites; Catalytic Domain; CpG Islands; Crystallography, X-Ray; Cytosine; DNA; Endodeoxyribonucleases; Furans; Guanine; Humans; Protein Conformation; Substrate Specificity | 2012 |
Commentary: combination therapy with two nucleos(t)ide analogues in chronic hepatitis B.
Topics: Adenine; Antiviral Agents; Drug Resistance; Drug Therapy, Combination; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir | 2012 |
Nucleic Acid Structure Investigated by UV Resonance Raman Spectroscopy: Protonation Effects and A-Tract Structure.
Topics: Adenine; DNA; Guanine; Hydrogen-Ion Concentration; Spectrum Analysis, Raman; Vibration | 2000 |
Hepatitis B prophylaxis post liver transplantation with newer nucleos(t)ide analogues after hepatitis B immunoglobulin discontinuation.
Topics: Adenine; Adult; Aged; Antiviral Agents; Drug Administration Schedule; Drug Therapy, Combination; Female; Guanine; Hepatitis B; Hepatitis B virus; Humans; Immunoglobulins; Lamivudine; Liver Transplantation; Male; Middle Aged; Nucleotides; Organophosphonates; Secondary Prevention; Tenofovir; Treatment Outcome; Young Adult | 2012 |
The mechanism of guanine alkylation by nitrogen mustards: a computational study.
Topics: Adenine; Alkylation; Antineoplastic Agents, Alkylating; Guanine; Kinetics; Mechlorethamine; Melphalan; Molecular Structure; Quantum Theory; Thermodynamics | 2012 |
The importance of genetic variants in TNFα for periodontal disease in a cohort of coronary patients.
Topics: Adenine; Aged; Alleles; Bacteria; Cohort Studies; Coronary Disease; Dental Plaque Index; Diabetes Complications; Eubacterium; Female; Genetic Variation; Genotype; Gingival Hemorrhage; Guanine; Haplotypes; Humans; Interleukin-6; Male; Periodontal Attachment Loss; Periodontal Pocket; Periodontitis; Polymorphism, Single Nucleotide; Porphyromonas gingivalis; Prevotella intermedia; Prospective Studies; Risk Factors; Sex Factors; Smoking; Tumor Necrosis Factor-alpha | 2012 |
Cleft lip in oculodentodigital dysplasia suggests novel roles for connexin43.
Topics: Abnormalities, Multiple; Adenine; Animals; Bone Morphogenetic Protein 4; Child, Preschool; Cleft Lip; Connexin 43; Epithelium; Exons; Eye Abnormalities; Fingers; Galactosyltransferases; Glucosyltransferases; Glutamic Acid; Guanine; Heterozygote; Humans; Infant; Introns; Lip; Lysine; Male; Mice; Models, Animal; Polymorphism, Single Nucleotide; Tooth Abnormalities; Transcription Factor AP-2 | 2012 |
MMP13 polymorphism decreases risk for dental caries.
Topics: Adenine; Adolescent; Alleles; Child; Child, Preschool; Cohort Studies; Cross-Sectional Studies; Dental Caries; Dental Caries Susceptibility; Dentition, Mixed; Dietary Sucrose; DMF Index; Female; Gene Frequency; Gene-Environment Interaction; Genotype; Guanine; Humans; Male; Matrix Metalloproteinase 13; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mutation; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Protease Inhibitors; Tissue Inhibitor of Metalloproteinase-2; Young Adult | 2012 |
Borrelia burgdorferi harbors a transport system essential for purine salvage and mammalian infection.
Topics: Adenine; Animals; Borrelia burgdorferi; Disease Models, Animal; Female; Guanine; Hypoxanthine; Lyme Disease; Membrane Transport Proteins; Mice; Mice, Inbred C3H; Plasmids; Virulence Factors | 2012 |
Current practice of chronic hepatitis B treatment in Southern Italy.
Topics: Adenine; Adult; Age Factors; Aged; Aged, 80 and over; Antiviral Agents; Female; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interferon-alpha; Italy; Lamivudine; Male; Middle Aged; Nucleosides; Organophosphonates; Polyethylene Glycols; Practice Patterns, Physicians'; Pyrimidinones; Recombinant Proteins; Telbivudine; Tenofovir; Thymidine; Young Adult | 2012 |
Identification and characterization of an adenine to guanine transition within intron 10 of the factor VIII gene as a causative mutation in a patient with mild haemophilia A.
Topics: Adenine; Aged; DNA Mutational Analysis; Factor VIII; Genotype; Guanine; Hemophilia A; Humans; Introns; Male; Nucleotides; Point Mutation; Risk Factors | 2013 |
TAL effector RVD specificities and efficiencies.
Topics: Adenine; Amino Acid Motifs; Deoxyribonucleases; DNA-Binding Proteins; Guanine; Humans; Minisatellite Repeats; Transcriptional Activation; Xanthomonas | 2012 |
Chromium (VI) induces both bulky DNA adducts and oxidative DNA damage at adenines and guanines in the p53 gene of human lung cells.
Topics: Adenine; Adenocarcinoma; Carcinogens, Environmental; Cell Line, Tumor; Chromium; DNA Adducts; DNA Damage; Genes, p53; Guanine; Humans; Lung Neoplasms; Mutagens; Oxidative Stress | 2012 |
Restored function of HBV-specific T cells after long-term effective therapy with nucleos(t)ide analogues.
Topics: Adenine; Antiviral Agents; Cells, Cultured; DNA, Viral; Genotype; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-gamma; Interleukin-1; Lamivudine; Organophosphonates; T-Lymphocytes; Tenofovir; Tumor Necrosis Factor-alpha | 2012 |
Comparison of the efficacy of tenofovir and entecavir for the treatment of nucleos(t)ide-naive patients with chronic hepatitis B.
Topics: Adenine; Adolescent; Adult; Aged; Alanine Transaminase; Antiviral Agents; DNA, Viral; Female; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates; Retrospective Studies; Tenofovir; Treatment Outcome; Young Adult | 2012 |
Acute liver failure resulting from discontinuation of nucleoside analogues in chronic hepatitis B patients: a report of two cases.
Topics: Adenine; Adult; Antiviral Agents; Guanine; Hepatitis B, Chronic; Histocytochemistry; Humans; Lamivudine; Liver Failure, Acute; Liver Transplantation; Male; Medication Adherence; Necrosis; Organophosphonates; Telbivudine; Thymidine | 2013 |
Quantum mechanical calculations for the misincorporation of nucleotides opposite mutagenic 3,N4-ethenocytosine.
Topics: Adenine; Base Pairing; Binding Sites; Cytosine; DNA Adducts; Guanine; Hydrogen Bonding; Models, Molecular; Mutagens; Nucleic Acid Conformation; Quantum Theory; Thermodynamics; Thymine | 2012 |
Probing murine methyltransfease Dnmt3a interactions with benzo[a]pyrene-modified DNA by fluorescence methods.
Topics: Adenine; Animals; Base Sequence; Benzo(a)pyrene; Binding Sites; Biocatalysis; Catalytic Domain; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Adducts; DNA Methylation; DNA Methyltransferase 3A; Guanine; Kinetics; Mice; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Protein Binding; Spectrometry, Fluorescence; Stereoisomerism; Substrate Specificity | 2012 |
Sequence selectivity of azinomycin B in DNA alkylation and cross-linking: a QM/MM study.
Topics: Adenine; Alkylation; Base Sequence; Cross-Linking Reagents; DNA; Guanine; Intercellular Signaling Peptides and Proteins; Models, Molecular; Naphthalenes; Peptides; Quantum Theory; Static Electricity; Thermodynamics | 2013 |
Comparison of rescue strategies in lamivudine-resistant patients with chronic hepatitis B.
Topics: Adenine; Adult; Antiviral Agents; China; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Salvage Therapy; Treatment Outcome | 2012 |
Modeling, substrate docking, and mutational analysis identify residues essential for the function and specificity of a eukaryotic purine-cytosine NCS1 transporter.
Topics: Adenine; Amino Acid Motifs; Amino Acid Substitution; Aspergillus nidulans; Conserved Sequence; Cytosine; Fungal Proteins; Guanine; Hydrogen Bonding; Hypoxanthine; Kinetics; Molecular Docking Simulation; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Phenotype; Protein Binding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Structural Homology, Protein; Substrate Specificity; Symporters | 2012 |
Insight on the interaction of polychlorobiphenyl with nucleic acid-base.
Topics: Adenine; Base Pairing; Cytosine; DNA; Environmental Pollutants; Guanine; Humans; Hydrogen Bonding; Intercalating Agents; Models, Molecular; Nucleic Acid Conformation; Polychlorinated Biphenyls; Quantum Theory; Static Electricity; Thermodynamics; Thymine | 2013 |
Tenofovir monotherapy and tenofovir plus entecavir combination as rescue therapy for entecavir partial responders.
Topics: Adenine; Adult; Analysis of Variance; Antiviral Agents; Chi-Square Distribution; Drug Therapy, Combination; Female; Guanine; Hepatitis B, Chronic; Humans; Liver Function Tests; Male; Middle Aged; Organophosphonates; Polymerase Chain Reaction; Retrospective Studies; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Outcome | 2012 |
Evaluation of anti-HBV drug resistant mutations among patients with acute symptomatic hepatitis B in the United States.
Topics: Acute Disease; Adenine; Adult; Antiviral Agents; Cohort Studies; Cross-Sectional Studies; Drug Resistance, Viral; Female; Genotype; Guanine; Hepatitis B; Humans; Lamivudine; Male; Mutation; Organophosphonates; Retrospective Studies; Sequence Analysis, DNA; United States | 2013 |
Genotype-specific mutations in the polymerase gene of hepatitis B virus potentially associated with resistance to oral antiviral therapy.
Topics: Adenine; Administration, Oral; Amino Acid Substitution; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Genes, pol; Genotype; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Mutation; Mutation Rate; Organophosphonates; Prevalence; Virus Replication | 2012 |
Physisorption of nucleobases on graphene: a comparative van der Waals study.
Topics: Adenine; Adsorption; Cytosine; Graphite; Guanine; Hydrophobic and Hydrophilic Interactions; Models, Chemical; Quantum Theory; Thymine; Uracil | 2012 |
Direct-acting DNA alkylating agents present in aqueous extracts of areca nut and its products.
Topics: Adenine; Alkylation; Animals; Areca; Cattle; Chromatography, Liquid; DNA; DNA Damage; Guanine; Molecular Structure; Nuts; Plant Extracts; Tandem Mass Spectrometry; Water | 2012 |
A three-layer ONIOM model for the outside binding of cationic porphyrins and nucleotide pair DNA.
Topics: Adenine; Base Pairing; Binding Sites; Cations, Monovalent; Cytosine; DNA; Gases; Guanine; Models, Chemical; Models, Molecular; Porphyrins; Quantum Theory; Sodium; Solutions; Thermodynamics; Thymine; Water | 2013 |
Hybridization potential of oligonucleotides comprising 3'-O-methylated altritol nucleosides.
Topics: Adenine; Cytosine; Guanine; Magnetic Resonance Spectroscopy; Nucleic Acid Hybridization; Nucleosides; Oligonucleotides; RNA, Small Interfering; Sequence Analysis, RNA; Solid-Phase Synthesis Techniques; Sugar Alcohols; Thermodynamics; Ultraviolet Rays; Uracil | 2012 |
Long-term efficacy and safety of lamivudine, entecavir, and tenofovir for treatment of hepatitis B virus-related cirrhosis.
Topics: Adenine; Adult; Aged; Alanine Transaminase; Antiviral Agents; Blood Chemical Analysis; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver Cirrhosis; Male; Middle Aged; Organophosphonates; Retrospective Studies; Tenofovir; Treatment Outcome; Turkey | 2013 |
The 2012 revised Dutch national guidelines for the treatment of chronic hepatitis B virus infection.
Topics: Adenine; Antiviral Agents; Drug Approval; Drug Resistance, Viral; Female; Guanine; Hepatitis B, Chronic; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Milk, Human; Netherlands; Nucleosides; Organophosphonates; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications, Infectious; Renal Insufficiency; Telbivudine; Tenofovir; Thymidine | 2012 |
Multidrug-resistant hepatitis B virus resulting from sequential monotherapy with lamivudine, adefovir, and entecavir: clonal evolution during lamivudine plus adefovir therapy.
Topics: Adenine; Adult; Antiviral Agents; Clonal Evolution; DNA, Viral; Drug Resistance, Multiple, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation, Missense; Organophosphonates; RNA-Directed DNA Polymerase | 2013 |
Effect of nucleos(t)ide analogue therapy on hepatocarcinogenesis in chronic hepatitis B patients: a propensity score analysis.
Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; alpha-Fetoproteins; Antiviral Agents; Child; Child, Preschool; Female; Follow-Up Studies; Guanine; Hepatitis B Core Antigens; Hepatitis B, Chronic; Humans; Incidence; Lamivudine; Liver Neoplasms; Male; Middle Aged; Organophosphonates; Proportional Hazards Models | 2013 |
The A/G allele of eIF3a rs3740556 predicts platinum-based chemotherapy resistance in lung cancer patients.
Topics: Adenine; Adult; Alleles; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Pharmacological; Carcinoma, Squamous Cell; Drug Resistance, Neoplasm; Eukaryotic Initiation Factor-3; Genetic Association Studies; Guanine; Humans; Lung Neoplasms; Male; Middle Aged; Mutation; Platinum Compounds; Polymorphism, Genetic; Predictive Value of Tests; Prognosis | 2013 |
Postlingual hearing loss as a mitochondrial 3243A>G mutation phenotype.
Topics: Adenine; Adolescent; Adult; Age of Onset; Brain; DNA; DNA Mutational Analysis; DNA, Mitochondrial; Female; Guanine; Hearing Loss, Sensorineural; Heterozygote; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Mutation; Poland; Sex Factors | 2012 |
Theoretical study on the binding mechanism between N6-methyladenine and natural DNA bases.
Topics: Adenine; Base Pairing; Cytosine; DNA; Guanine; Hydrogen Bonding; Models, Molecular; Thermodynamics | 2013 |
Pressure-tuning infrared and Raman microscopy study of the DNA bases: adenine, guanine, cytosine, and thymine.
Topics: Adenine; Cytosine; Guanine; Models, Chemical; Molecular Structure; Pressure; Spectrophotometry, Infrared; Spectrum Analysis, Raman; Thymine | 2013 |
Association of CD28 and CTLA-4 gene polymorphisms with aggressive periodontitis in Brazilians.
Topics: Adenine; Adolescent; Adult; Aged; Aggressive Periodontitis; Brazil; CD28 Antigens; Chronic Periodontitis; CTLA-4 Antigen; Cytosine; DNA; Female; Gene Frequency; Genetic Markers; Genetic Predisposition to Disease; Genotype; Guanine; Humans; Male; Middle Aged; Periodontal Attachment Loss; Periodontal Pocket; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Smoking; Thymine; Young Adult | 2013 |
XRCC1 gene polymorphisms and risk of ameloblastoma.
Topics: Adenine; Adult; Ameloblastoma; Arginine; Codon; DNA Repair; DNA-Binding Proteins; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glycine; Guanine; Haplotypes; Histidine; Humans; Male; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Risk Factors; Sequence Analysis, DNA; Thailand; Thymine; Tryptophan; X-ray Repair Cross Complementing Protein 1 | 2013 |
The efficacy of adefovir plus entecavir combination therapy in patients with chronic hepatitis B refractory to both lamivudine and adefovir.
Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Treatment Failure | 2013 |
Theoretical investigation of the proton transfer mechanism in guanine-cytosine and adenine-thymine base pairs.
Topics: Adenine; Computer Simulation; Cytosine; Guanine; Models, Chemical; Models, Molecular; Protons; Thymine | 2012 |
The short-term efficacy of entecavir in lamivudine-resistant chronic hepatitis B: influence of sequential adefovir-refractoriness.
Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Liver Function Tests; Male; Middle Aged; Organophosphonates; Retrospective Studies; Treatment Outcome | 2013 |
Treatment of lamivudine-resistant chronic hepatitis B infection: a multicenter retrospective study.
Topics: Adenine; Adult; Antiviral Agents; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; Female; Follow-Up Studies; Guanine; Hepatitis B, Chronic; Humans; Kaplan-Meier Estimate; Lamivudine; Logistic Models; Male; Middle Aged; Multivariate Analysis; Organophosphonates; Retrospective Studies; Treatment Outcome; Viral Load | 2013 |
Long-term hepatitis B surface antigen (HBsAg) kinetics during nucleoside/nucleotide analogue therapy: finite treatment duration unlikely.
Topics: Adenine; Adult; Aged; Aged, 80 and over; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Female; Guanine; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Kinetics; Lamivudine; Longitudinal Studies; Male; Middle Aged; Nucleosides; Nucleotides; Organophosphonates; Tenofovir | 2013 |
Simultaneous quantitative analysis of N3-ethyladenine and N7-ethylguanine in human leukocyte deoxyribonucleic acid by stable isotope dilution capillary liquid chromatography-nanospray ionization tandem mass spectrometry.
Topics: Adenine; Adolescent; Adult; Chromatography, High Pressure Liquid; DNA; DNA Adducts; Female; Guanine; Humans; Isotope Labeling; Leukocytes; Male; Reproducibility of Results; Sensitivity and Specificity; Smoking; Spectrometry, Mass, Electrospray Ionization; Statistics, Nonparametric; Tandem Mass Spectrometry | 2013 |
Early viral suppression predicts good postoperative survivals in patients with hepatocellular carcinoma with a high baseline HBV-DNA load.
Topics: Adenine; Adult; Antiviral Agents; Carcinoma, Hepatocellular; Disease-Free Survival; DNA, Viral; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Kaplan-Meier Estimate; Lamivudine; Liver Neoplasms; Male; Middle Aged; Multivariate Analysis; Neoplasm Recurrence, Local; Organophosphonates; Portal Vein; Proportional Hazards Models; Retrospective Studies; Risk Factors; Viral Load | 2013 |
Management of chronic hepatitis B: Canadian Association for the Study of the Liver consensus guidelines.
Topics: Adenine; Allied Health Personnel; Antibodies, Viral; Antiviral Agents; Canada; Coinfection; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B Surface Antigens; Hepatitis B Vaccines; Hepatitis B virus; Hepatitis B, Chronic; Hepatitis C; Humans; Interferons; Kidney Diseases; Liver; Organophosphonates; Pregnancy; Pregnancy Complications, Infectious; Tenofovir | 2012 |
Experience of anti-viral therapy in hepatitis B-associated membranous nephropathy, including Lamivudine-resistant strains.
Topics: Adenine; Adult; Antiviral Agents; Arabinofuranosyluracil; Drug Resistance, Viral; Female; Glomerulonephritis, Membranous; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Young Adult | 2012 |
Interaction of cisplatin with adenine and guanine: a combined IRMPD, MS/MS, and theoretical study.
Topics: Adenine; Cisplatin; Guanine; Organoplatinum Compounds; Quantum Theory; Spectrophotometry, Infrared; Tandem Mass Spectrometry | 2013 |
Structure, stability and function of 5-chlorouracil modified A:U and G:U base pairs.
Topics: Adenine; Base Pairing; Deoxyribonuclease EcoRI; DNA, B-Form; Guanine; Models, Molecular; Ribonuclease H; Thermodynamics; Uracil | 2013 |
Calculated pK(a)'s of the DNA base radical ions.
Topics: Adenine; Cytosine; DNA; Electron Spin Resonance Spectroscopy; Guanine; Molecular Dynamics Simulation; Thermodynamics; Thymine | 2013 |
Study of DNA base-Li doped SiC nanotubes in aqueous solutions: a computer simulation study.
Topics: Adenine; Carbon Compounds, Inorganic; Computer Simulation; Cytosine; DNA; Guanine; Kinetics; Lithium; Monte Carlo Method; Nanotubes; Quantum Theory; Silicon Compounds; Solutions; Thermodynamics; Thymine; Water | 2013 |
Should chronic hepatitis B be treated as early as possible?
Topics: Adenine; Adult; Antiviral Agents; Belgium; Cost-Benefit Analysis; Early Diagnosis; Guanine; Health Care Surveys; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Liver Cirrhosis; Markov Chains; Middle Aged; Organophosphonates; Quality of Life; Secondary Prevention; Tenofovir; Treatment Outcome; Viral Load | 2013 |
[Antiviral therapy for patients with chronic hepatitis B with multi-drug resistance to nucleoside analogues].
Topics: Adenine; Aged; Aged, 80 and over; Antiviral Agents; Drug Resistance, Multiple, Viral; Female; Guanine; Hepatitis B, Chronic; Humans; Male; Middle Aged; Nucleosides; Organophosphonates | 2013 |
Kinetics and prediction of HBsAg loss during therapy with analogues in patients affected by chronic hepatitis B HBeAg negative and genotype D.
Topics: Adenine; Aged; Antiviral Agents; Biomarkers; Chi-Square Distribution; DNA, Viral; Female; Genotype; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Kinetics; Lamivudine; Male; Middle Aged; Organophosphonates; Retrospective Studies; Telbivudine; Tenofovir; Thymidine; Treatment Outcome | 2013 |
Outcome of various treatments for posttransplant hepatitis B virus recurrence.
Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; Biomarkers; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Guanine; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Immunoglobulins, Intravenous; Immunologic Factors; Lamivudine; Liver Transplantation; Male; Middle Aged; Organophosphonates; Recurrence; Retrospective Studies; Treatment Outcome; Young Adult | 2013 |
Electrochemical characterization of redox polymer modified electrode developed for monitoring of adenine.
Topics: Adenine; Electric Impedance; Electrochemistry; Electrodes; Ferrous Compounds; Guanine; Hydrogen-Ion Concentration; Microscopy, Electron, Scanning; Oxidation-Reduction; Platinum; Polymers; Polyvinyls; Uric Acid | 2013 |
Benchmarking for perturbative triple-excitations in EE-EOM-CC methods.
Topics: Adenine; Benchmarking; Cytosine; Electrons; Guanine; Quantum Theory; Thermodynamics; Thymine | 2013 |
High frequency of complex mutational patterns in lamivudine resistant hepatitis B virus isolates.
Topics: Adenine; Antiviral Agents; Codon, Nonsense; Drug Resistance, Viral; Genotype; Guanine; Hepatitis B; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Lamivudine; Mutation, Missense; Organophosphonates; RNA-Directed DNA Polymerase | 2013 |
Benchmark studies on the building blocks of DNA. 3. Watson-Crick and stacked base pairs.
Topics: Adenine; Base Pairing; Cytosine; DNA; Guanine; Hydrogen Bonding; Models, Molecular; Quantum Theory; Thymine | 2013 |
Excited state proton-coupled electron transfer in 8-oxoG-C and 8-oxoG-A base pairs: a time dependent density functional theory (TD-DFT) study.
Topics: Adenine; Base Pairing; Cytosine; DNA; Electrons; Guanine; Models, Molecular; Protons; Quantum Theory | 2013 |
Individualized treatment of HBeAg-negative chronic hepatitis B using pegylated interferon-α2a as first-line and week-12 HBV DNA/HBsAg stopping rule: a cost-effectiveness analysis.
Topics: Adenine; Adult; Antiviral Agents; Carcinoma, Hepatocellular; Cost-Benefit Analysis; Drug Administration Schedule; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Liver Cirrhosis; Liver Neoplasms; Male; Markov Chains; Organophosphonates; Polyethylene Glycols; Precision Medicine; Prognosis; Quality-Adjusted Life Years; Recombinant Proteins; Tenofovir; Viral Load | 2013 |
[Cost-effectiveness of nucleoside/nucleotide analogues in chronic hepatitis B].
Topics: Adenine; Antiviral Agents; Cost-Benefit Analysis; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B, Chronic; Humans; Markov Chains; Models, Theoretical; Organophosphonates; Quality-Adjusted Life Years; Tenofovir | 2012 |
Functional evaluation of mutations in the tissue-nonspecific alkaline phosphatase gene.
Topics: Adenine; Alkaline Phosphatase; Alleles; Calcification, Physiologic; Cell Culture Techniques; Cell Line, Tumor; Child; Child, Preschool; Cytosine; Exons; Genotype; Guanine; Heterozygote; Humans; Hypophosphatasia; Introns; Mutagenesis, Site-Directed; Mutation; Osteosarcoma; Phenotype; Plasmids; Thymine; Transfection | 2012 |
Increased eGFR with telbivudine in combination therapy of chronic hepatitis B infection.
Topics: Adenine; Antiviral Agents; Drug Therapy, Combination; Glomerular Filtration Rate; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Organophosphonates; Telbivudine; Tenofovir; Thymidine | 2014 |
Fluorescence monitoring of riboswitch transcription regulation using a dual molecular beacon assay.
Topics: Adenine; Bacillus subtilis; Drug Evaluation, Preclinical; Fluorescent Dyes; Gene Expression Regulation; Guanine; Ligands; Nucleic Acid Probes; Nucleobase Transport Proteins; Riboswitch; Spectrometry, Fluorescence; Transcription, Genetic | 2013 |
Excited state properties of naphtho-homologated xxDNA bases and effect of methanol solution, deoxyribose, and base pairing.
Topics: Adenine; Base Pairing; Computer Simulation; Cytosine; Deoxyribose; DNA; Guanine; Methanol; Models, Molecular; Naphthols; Thymine | 2013 |
Prevention of de novo hepatitis B with adefovir plus vaccination in recipients of liver transplants from core antibody-positive donors.
Topics: Adenine; Adult; Aged; Antiviral Agents; Biomarkers; Deoxycytidine; DNA, Viral; Drug Substitution; Emtricitabine; Guanine; Hepatitis B; Hepatitis B Antibodies; Hepatitis B Core Antigens; Hepatitis B Vaccines; Hepatitis B virus; Humans; Liver Transplantation; Middle Aged; Organophosphonates; Tenofovir; Time Factors; Tissue Donors; Treatment Outcome | 2013 |
Prevention of de novo hepatitis B in recipients of core antibody-positive livers with lamivudine and other nucleos(t)ides: a 12-year experience.
Topics: Adenine; Adult; Aged; Analysis of Variance; Antiviral Agents; Biomarkers; Chi-Square Distribution; DNA, Viral; Donor Selection; Female; Guanine; Hepatitis B; Hepatitis B Antibodies; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Immunosuppressive Agents; Lamivudine; Liver Transplantation; Logistic Models; Male; Middle Aged; Organophosphonates; Retrospective Studies; Risk Factors; Tenofovir; Time Factors; Tissue Donors; Treatment Outcome; Viral Load | 2013 |
Adenine-DNA adducts derived from the highly tumorigenic Dibenzo[a,l]pyrene are resistant to nucleotide excision repair while guanine adducts are not.
Topics: Adenine; Benzopyrenes; DNA Adducts; DNA Repair; Guanine; HeLa Cells; Humans; Models, Molecular; Molecular Dynamics Simulation; Molecular Structure; Structure-Activity Relationship; Temperature | 2013 |
Chronic hepatitis B treatment initiation and modification patterns in five European countries: a 2-year longitudinal, non-interventional study.
Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; Alanine Transaminase; Antiviral Agents; Disease Management; DNA, Viral; Europe; Female; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Longitudinal Studies; Male; Middle Aged; Organophosphonates; Polyethylene Glycols; Prospective Studies; Recombinant Proteins; Tenofovir | 2014 |
The use of the GSAM approach for the structural investigation of low-lying isomers of molecular clusters from density-functional-theory-based potential energy surfaces: the structures of microhydrated nucleic acid bases.
Topics: Adenine; Cytosine; Guanine; Isomerism; Models, Molecular; Quantum Theory; Surface Properties; Thermodynamics; Thymine; Uracil; Water | 2013 |
Caffeine as base analogue of adenine or guanine: a theoretical study.
Topics: Adenine; Base Pairing; Caffeine; Cytosine; DNA; Guanine; Models, Molecular; Mutagenesis; Nucleic Acid Conformation; Quantum Theory; Thymine | 2013 |
Snapshot on drug-resistance rate and profiles in patients with chronic hepatitis B receiving nucleos(t)ide analogues in clinical practice.
Topics: Adenine; Adult; Antiviral Agents; Cohort Studies; DNA, Viral; Drug Resistance, Viral; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Recurrence; Telbivudine; Thymidine; Treatment Outcome | 2013 |
Exciplexes and conical intersections lead to fluorescence quenching in π-stacked dimers of 2-aminopurine with natural purine nucleobases.
Topics: 2-Aminopurine; Adenine; Dimerization; Fluorescence; Guanine; Models, Molecular | 2013 |
Oral nucleoside/nucleotide analogs without hepatitis B immune globulin after liver transplantation for hepatitis B.
Topics: Adenine; Adult; Aged; Antiviral Agents; DNA, Viral; Drug Therapy, Combination; Female; Follow-Up Studies; Guanine; Hepatitis B Antibodies; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Kaplan-Meier Estimate; Lamivudine; Liver Transplantation; Male; Middle Aged; Organophosphonates; Postoperative Care; Proportional Hazards Models; Secondary Prevention; Survival Rate; Viral Load; Young Adult | 2013 |
Base-specific ionization of deprotonated nucleotides by resonance enhanced two-photon detachment.
Topics: Adenine; Cytosine; DNA; DNA Damage; Electrons; Guanine; Models, Molecular; Photons; Protons; Thermodynamics; Thymine | 2013 |
Effect of genetic polymorphisms in CA6 gene on the expression and catalytic activity of human salivary carbonic anhydrase VI.
Topics: Adenine; Adolescent; Alleles; Biocatalysis; Carbonic Anhydrases; Cytosine; Female; Gene Frequency; Genotype; Guanine; Humans; Linkage Disequilibrium; Male; Multigene Family; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Saliva; Salivary Proteins and Peptides; Thymine; Young Adult | 2013 |
Comparison of re-treatment outcomes of lamivudine plus adefovir or entecavir in chronic hepatitis B patients with viral relapse after cessation of adefovir.
Topics: Adenine; Adult; Antiviral Agents; Case-Control Studies; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver Function Tests; Male; Organophosphonates; Prospective Studies; Recurrence; Treatment Outcome | 2013 |
Long distance charge transport through DNA: quantification and extension of the hopping model.
Topics: Adenine; Base Sequence; Cations; DNA; Electron Transport; Guanine; Kinetics; Models, Chemical; Oxidation-Reduction | 2000 |
Entecavir plus adefovir rescue therapy for chronic hepatitis B patients after multiple treatment failures in real-life practice.
Topics: Adenine; Adult; Antiviral Agents; Creatine Kinase; Creatinine; DNA, Viral; Female; Guanine; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates; Salvage Therapy; Treatment Outcome; Viral Load | 2013 |
Prophylaxis in HBV-infected liver transplant patients: end of the HBIG era?
Topics: Adenine; Antiviral Agents; Female; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Liver Transplantation; Male; Organophosphonates | 2013 |
Noncompetitive inhibition of hepatitis B virus reverse transcriptase protein priming and DNA synthesis by the nucleoside analog clevudine.
Topics: Adenine; Arabinofuranosyluracil; DNA, Viral; Guanine; HEK293 Cells; Hepatitis B virus; Humans; Organophosphonates; Protein Binding; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Tenofovir; Viral Proteins | 2013 |
Living related liver transplantation for hepatitis B-related liver disease without hepatitis B immune globulin prophylaxis.
Topics: Adenine; Adolescent; Adult; Aged; Antiviral Agents; DNA, Viral; Drug Resistance; Drug Therapy, Combination; Female; Follow-Up Studies; Guanine; Hepatitis B; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Immunoglobulins; Immunosuppression Therapy; Immunosuppressive Agents; Lamivudine; Liver Transplantation; Living Donors; Male; Middle Aged; Organophosphonates; Prospective Studies; Recurrence; Tenofovir; Treatment Outcome | 2013 |
Highly selective electrochemical biosensor for the determination of folic acid based on DNA modified-pencil graphite electrode using response surface methodology.
Topics: Adenine; Analysis of Variance; Biosensing Techniques; Calibration; DNA; Electrochemistry; Electrodes; Flour; Folic Acid; Graphite; Guanine; Oxidation-Reduction; Spectrophotometry, Ultraviolet; Statistics as Topic; Triticum | 2013 |
WHO survey finds half of countries do not have clinical guidelines for treating hepatitis.
Topics: Adenine; Antiviral Agents; Drugs, Essential; Global Health; Guanine; Health Priorities; Hepatitis B; Hepatitis C; Humans; Interferon alpha-2; Interferon-alpha; Organophosphonates; Polyethylene Glycols; Practice Guidelines as Topic; Recombinant Proteins; Tenofovir; World Health Organization | 2013 |
Nuclear quantum effect and temperature dependency on the hydrogen-bonded structure of base pairs.
Topics: Adenine; Base Pairing; Guanine; Hydrogen Bonding; Monte Carlo Method; Nucleic Acid Conformation; Quantum Theory; Temperature; Thymine | 2013 |
The generation of induced pluripotent stem cells from a patient with KCNH2 G603D, without LQT2 disease associated symptom.
Topics: Adenine; Aspartic Acid; Cell Culture Techniques; Child; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Genome, Human; Glycine; Guanine; Homeodomain Proteins; Humans; Long QT Syndrome; Male; Nanog Homeobox Protein; Octamer Transcription Factor-3; Pluripotent Stem Cells; Polymorphism, Single Nucleotide; Sequence Analysis, DNA | 2013 |
Oxidative stress-induced mutagenesis in single-strand DNA occurs primarily at cytosines and is DNA polymerase zeta-dependent only for adenines and guanines.
Topics: Adenine; Cytosine; DNA; DNA-Directed DNA Polymerase; DNA, Single-Stranded; Guanine; Hydrogen Peroxide; Mutagenesis; Oxidative Stress; Paraquat; Reactive Oxygen Species; Saccharomycetales | 2013 |
Electrochemical biosensor based on silver nanoparticles-polydopamine-graphene nanocomposite for sensitive determination of adenine and guanine.
Topics: Adenine; Animals; Biosensing Techniques; DNA; Electrochemical Techniques; Fishes; Graphite; Guanine; Indoles; Male; Metal Nanoparticles; Nanocomposites; Polymers; Silver; Spermatozoa | 2013 |
[Detection of resistance mutations in chronic hepatitis B patients receiving antiviral therapy for over one year].
Topics: Adenine; Adolescent; Adult; Aged; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Polymerase Chain Reaction; Young Adult | 2013 |
[HBV vaccine escape mutations in a chronic hepatitis B patient treated with nucleos(t)ide analogues].
Topics: Adenine; Biopsy; Drug Resistance, Multiple, Viral; Female; Genes, pol; Guanine; Hepatitis B Vaccines; Hepatitis B virus; Hepatitis B, Chronic; Humans; Liver; Middle Aged; Mutation; Nucleosides; Nucleotides; Organophosphonates; Tenofovir | 2013 |
Effects of hypoxanthine substitution in peptide nucleic acids targeting KRAS2 oncogenic mRNA molecules: theory and experiment.
Topics: Adenine; Algorithms; Base Pairing; Circular Dichroism; Guanine; Humans; Hypoxanthine; Models, Molecular; Molecular Dynamics Simulation; Nucleic Acid Denaturation; Peptide Nucleic Acids; Point Mutation; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; RNA, Messenger; Transition Temperature; Uracil | 2013 |
Optimization of global DNA methylation measurement by LC-MS/MS and its application in lung cancer patients.
Topics: Adenine; Adenocarcinoma; Aged; Carcinoma, Squamous Cell; Chromatography, Liquid; Deoxycytidine; DNA Methylation; DNA, Neoplasm; Female; Fungal Proteins; Guanine; Humans; Indicator Dilution Techniques; Limit of Detection; Lung Neoplasms; Male; Middle Aged; Reproducibility of Results; Single-Strand Specific DNA and RNA Endonucleases; Solid Phase Extraction; Tandem Mass Spectrometry; Tumor Microenvironment | 2013 |
Simultaneous determination of 10 nucleosides and nucleobases in Antrodia camphorata using QTRAP LC-MS/MS.
Topics: Adenine; Antrodia; Chromatography, Liquid; Guanine; Nucleosides; Plant Extracts; Reproducibility of Results; Tandem Mass Spectrometry; Uracil; Xanthine | 2014 |
Long-term efficacy of entecavir plus adefovir combination therapy versus entecavir monotherapy in adefovir refractory chronic hepatitis B patients with prior lamivudine resistance.
Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Retrospective Studies; Treatment Outcome | 2014 |
Aqueous Heck cross-coupling preparation of acrylate-modified nucleotides and nucleoside triphosphates for polymerase synthesis of acrylate-labeled DNA.
Topics: Acrylates; Adenine; DNA-Directed DNA Polymerase; Guanine; Molecular Structure; Nucleosides; Nucleotides | 2013 |
Non-covalent interactions: complexes of guanidinium with DNA and RNA nucleobases.
Topics: Adenine; Cations; Computer Simulation; Cytosine; DNA; Electrons; Guanidine; Guanine; Hydrogen Bonding; Models, Molecular; RNA; Thymine; Uracil; Water | 2013 |
π- vs σ-radical states of one-electron-oxidized DNA/RNA bases: a density functional theory study.
Topics: Adenine; Cytosine; DNA; Electrons; Gases; Guanine; Models, Molecular; Oxidation-Reduction; RNA; Solutions; Solvents; Thymine; Uracil; Water | 2013 |
Low-potential amperometric determination of purine derivatives through surface oxide regeneration method.
Topics: Adenine; Copper; Electrochemical Techniques; Guanine; Hypoxanthine; Limit of Detection; Oxidation-Reduction; Purines; Uric Acid; Xanthine | 2013 |
Combination lamivudine and adefovir versus entecavir for the treatment of naïve chronic hepatitis B patients: a pilot study.
Topics: Adenine; Adult; Alanine Transaminase; Analysis of Variance; Aspartate Aminotransferases; Bilirubin; Drug Combinations; Enzyme-Linked Immunosorbent Assay; Female; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Organophosphonates; Pilot Projects | 2013 |
DNA repair gene polymorphisms and risk of head and neck cancer in the Tunisian population.
Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; Alcohol Drinking; Arginine; Case-Control Studies; DNA Helicases; DNA Repair; DNA Repair Enzymes; DNA-Binding Proteins; Female; Gene-Environment Interaction; Genetic Predisposition to Disease; Glutamine; Guanine; Head and Neck Neoplasms; Humans; Lysine; Male; Middle Aged; Occupational Exposure; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Risk Factors; Smoking; X-ray Repair Cross Complementing Protein 1; Xeroderma Pigmentosum Group D Protein; Young Adult | 2014 |
Binding of a positron to nucleic base molecules and their pairs.
Topics: Adenine; Base Pairing; Cytosine; Guanine; Models, Molecular; Oxidation-Reduction; Static Electricity; Thymine | 2013 |
A comparative DFT study on aquation and nucleobase binding of ruthenium (II) and osmium (II) arene complexes.
Topics: Adenine; Antineoplastic Agents; Cell Line, Tumor; Guanine; Humans; Organometallic Compounds; Osmium; Picolinic Acids; Quantum Theory; Ruthenium | 2013 |
Direct analysis of tobacco-specific nitrosamine NNK and its metabolite NNAL in human urine by LC-MS/MS: evidence of linkage to methylated DNA lesions.
Topics: Adenine; Adult; Biomarkers; Chromatography, Liquid; Cotinine; DNA Methylation; Guanine; Humans; Limit of Detection; Nicotine; Nitrosamines; Pyridines; Sensitivity and Specificity; Smoking; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2014 |
Comparison of tenofovir and entecavir in patients with chronic HBV infection.
Topics: Adenine; Adult; Aged; DNA, Viral; Female; Guanine; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates; Retrospective Studies; Tenofovir | 2013 |
Efficacy of adefovir-based combination therapy for patients with Lamivudine- and entecavir-resistant chronic hepatitis B virus infection.
Topics: Adenine; Adult; Aged; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Retrospective Studies; Reverse Transcriptase Inhibitors; Treatment Outcome | 2013 |
Adenine-DNA adduct derived from the nitroreduction of 6-nitrochrysene is more resistant to nucleotide excision repair than guanine-DNA adducts.
Topics: Adenine; Animals; Benzo(a)pyrene; Cattle; Chrysenes; DNA; DNA Adducts; DNA Repair; Guanine; HeLa Cells; Humans; Mice; Oligonucleotides; Oxidation-Reduction; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2013 |
Specificities and pH profiles of adenine and hypoxanthine-guanine-xanthine phosphoribosyltransferases (nucleotide synthases) of the thermoacidophile archaeon Sulfolobus solfataricus.
Topics: Adenine; Amino Acid Sequence; Archaeal Proteins; Base Sequence; Guanine; Hydrogen-Ion Concentration; Hypoxanthine; Molecular Sequence Data; Pentosyltransferases; Substrate Specificity; Sulfolobus solfataricus; Xanthine | 2014 |
Kinetic mechanism of nick sealing by T4 RNA ligase 2 and effects of 3'-OH base mispairs and damaged base lesions.
Topics: Adenine; Apurinic Acid; Base Pairing; Base Sequence; Escherichia coli; Guanine; Kinetics; RNA Ligase (ATP); RNA, Double-Stranded; Viral Proteins | 2013 |
The role of androgen receptor gene in cyclosporine induced gingival overgrowth.
Topics: Adenine; Adult; Alleles; Base Pairing; Cross-Sectional Studies; Cyclosporine; Cytosine; Exons; Female; Gene Frequency; Genetic Variation; Gingival Overgrowth; Guanine; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Polymorphism, Genetic; Receptors, Androgen; Repetitive Sequences, Nucleic Acid; Young Adult | 2014 |
Establishment of dsDNA/GNs/chit/GCE biosensor and electrochemical study on interaction between 6-mercaptopurine and DNA.
Topics: Adenine; Adsorption; Biosensing Techniques; Chitosan; DNA; DNA Damage; Drug Monitoring; Electric Impedance; Electrochemistry; Electrodes; Graphite; Guanine; Humans; Mercaptopurine; Oxidation-Reduction; Oxygen | 2014 |
Insight into the interaction between DNA bases and defective graphenes: covalent or non-covalent.
Topics: Adenine; Adsorption; Cytosine; DNA; Fullerenes; Graphite; Guanine; Molecular Conformation; Thymine | 2014 |
Lack of association between lactotransferrin polymorphism and dental caries.
Topics: Adenine; Adolescent; Arginine; Case-Control Studies; Child; Cohort Studies; Czech Republic; Dental Calculus; Dental Caries; Dental Caries Susceptibility; Dental Plaque Index; DMF Index; Exons; Female; Gene Frequency; Genotype; Guanine; Humans; Lactoferrin; Lysine; Male; Periodontal Index; Polymorphism, Genetic | 2014 |
Free radical routes for prebiotic formation of DNA nucleobases from formamide.
Topics: Adenine; Evolution, Chemical; Formamides; Free Radicals; Guanine; Hypoxanthine; Molecular Structure; Purines | 2013 |
Matrix metalloproteinase (MMP)-8 and tissue inhibitor of MMP-1 (TIMP-1) gene polymorphisms in generalized aggressive periodontitis: gingival crevicular fluid MMP-8 and TIMP-1 levels and outcome of periodontal therapy.
Topics: Adenine; Adolescent; Adult; Aggressive Periodontitis; Alveolar Bone Loss; Biomarkers; Cytosine; Female; Follow-Up Studies; Gene Frequency; Genetic Predisposition to Disease; Genetic Variation; Genotype; Gingival Crevicular Fluid; Guanine; Humans; Male; Matrix Metalloproteinase 8; Middle Aged; Periodontal Attachment Loss; Polymorphism, Single Nucleotide; Sex Factors; Thymidine; Tissue Inhibitor of Metalloproteinase-1; Treatment Outcome; Young Adult | 2014 |
The substrate binding interface of alkylpurine DNA glycosylase AlkD.
Topics: Adenine; Catalytic Domain; DNA Glycosylases; DNA Repair; DNA-Binding Proteins; Guanine; Models, Molecular; Mutation; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Substrate Specificity | 2014 |
Noninvasive measurement of smoking-associated N(3)-ethyladenine and N(7)-ethylguanine in human salivary DNA by stable isotope dilution nanoflow liquid chromatography-nanospray ionization tandem mass spectrometry.
Topics: Adenine; Adult; Biomarkers; DNA Adducts; Female; Guanine; Humans; Hydrolysis; Indicator Dilution Techniques; Limit of Detection; Male; Nanotechnology; Reproducibility of Results; Saliva; Smoking; Solid Phase Extraction; Tandem Mass Spectrometry; Young Adult | 2014 |
Novel nonsense mutation in MSX1 in familial nonsyndromic oligodontia: subcellular localization and role of homeodomain/MH4.
Topics: Adenine; Anodontia; Axin Protein; Cell Culture Techniques; Cell Nucleus; Chromosome Segregation; Codon, Nonsense; Codon, Terminator; Dinucleotide Repeats; Exons; Female; Genes, Homeobox; Guanine; HEK293 Cells; Humans; Male; Middle Aged; MSX1 Transcription Factor; PAX9 Transcription Factor; Tryptophan; Young Adult | 2014 |
Chronic hepatitis B monitoring and treatment patterns in five European countries with different access and reimbursement policies.
Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Europe; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Hospitalization; Humans; Insurance, Health, Reimbursement; Interferon-alpha; Lamivudine; Longitudinal Studies; Male; Middle Aged; Monitoring, Ambulatory; Organophosphonates; Polyethylene Glycols; Prospective Studies; Recombinant Proteins; Tenofovir | 2014 |
Incorporated antivirals for chronic hepatitis B in Brazil: a cost-effectiveness analysis.
Topics: Adenine; Adult; Analysis of Variance; Antiviral Agents; Brazil; Cost-Benefit Analysis; Disease Progression; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Markov Chains; Organophosphonates; Tenofovir; Treatment Outcome | 2013 |
In depth analysis of the quenching of three fluorene-phenylene-based cationic conjugated polyelectrolytes by DNA and DNA bases.
Topics: Adenine; Cations; Cytosine; DNA; DNA, Single-Stranded; Electrolytes; Fluorenes; Fluorescence Resonance Energy Transfer; Guanine; Polymers; Quantum Theory; Thymine | 2014 |
Is the DPT tautomerization of the long A·G Watson-Crick DNA base mispair a source of the adenine and guanine mutagenic tautomers? A QM and QTAIM response to the biologically important question.
Topics: Adenine; Base Pairing; Guanine; Hydrogen Bonding; Models, Molecular; Point Mutation; Quantum Theory; Thermodynamics | 2014 |
Analysis of the association of COL2A1 and IGF-1 with mandibular prognathism in a Chinese population.
Topics: Adenine; Adolescent; Case-Control Studies; China; Collagen Type II; Female; Gene Frequency; Genetic Predisposition to Disease; Genome-Wide Association Study; Genotype; Guanine; Haplotypes; Heterozygote; Homozygote; Hong Kong; Humans; Insulin-Like Growth Factor I; Linkage Disequilibrium; Male; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Prognathism | 2014 |
Th1 and Th2 polymorphisms in Sjögren's syndrome and rheumatoid arthritis.
Topics: Adenine; Adult; Aged; Antibodies, Antinuclear; Arthritis, Rheumatoid; Autoantigens; Case-Control Studies; Cytosine; Female; Gene Frequency; Genetic Predisposition to Disease; Guanine; Humans; Interferon-gamma; Interleukin-10; Interleukin-6; Male; Middle Aged; Peptides, Cyclic; Polymorphism, Genetic; Rheumatoid Factor; Ribonucleoproteins; Saliva; Salivary Glands, Minor; Secretory Rate; Sjogren's Syndrome; SS-B Antigen; Thymine; Tumor Necrosis Factor-alpha; Young Adult | 2014 |
Detection of biomarkers with graphene nanoplatelets and nanoribbons.
Topics: Adenine; Ascorbic Acid; Biomarkers; Biosensing Techniques; Dopamine; Graphite; Guanine; Nanotubes, Carbon | 2014 |
Lamivudine compared with newer antivirals for prophylaxis of hepatitis B core antibody positive livers: a cost-effectiveness analysis.
Topics: Adenine; Antiviral Agents; Cohort Studies; Cost-Benefit Analysis; Decision Trees; Follow-Up Studies; Graft Survival; Guanine; Hepatitis B; Hepatitis B Antibodies; Hepatitis B Core Antigens; Hepatitis B virus; Humans; Lamivudine; Liver Transplantation; Markov Chains; Organophosphonates; Prognosis; Quality-Adjusted Life Years; Survival Rate; Tenofovir | 2014 |
Polymorphism of the CD14 and TLR4 genes and post-treatment apical periodontitis.
Topics: Adenine; Adult; Cytosine; Female; Gene Frequency; Genotype; Guanine; Homozygote; Humans; Lipopolysaccharide Receptors; Male; Periapical Periodontitis; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Radiography, Bitewing; Real-Time Polymerase Chain Reaction; Root Canal Therapy; Saliva; Smoking; Thymine; Toll-Like Receptor 4; Wound Healing | 2014 |
Efficacy of 2years of entecavir plus adefovir therapy in patients with chronic hepatitis B who had failed on prior nucleos(t)ide analog treatment.
Topics: Adenine; Adult; Alanine Transaminase; Antiviral Agents; Cohort Studies; DNA, Viral; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Female; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Male; Organophosphonates; Retrospective Studies; Salvage Therapy; Treatment Outcome | 2014 |
Tenofovir is superior to entecavir for achieving complete viral suppression in HBeAg-positive chronic hepatitis B patients with high HBV DNA.
Topics: Adenine; Adult; Antiviral Agents; California; Cohort Studies; DNA, Viral; Female; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates; Retrospective Studies; Tenofovir; Treatment Outcome | 2014 |
Association between cyclooxygenase-2 gene polymorphisms and head and neck squamous cell carcinoma risk.
Topics: 3' Untranslated Regions; Adenine; Adult; Aged; Alcohol Drinking; Carcinoma, Squamous Cell; Case-Control Studies; China; Cyclooxygenase 2; Cytosine; Ethnicity; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Guanine; Head and Neck Neoplasms; Heterozygote; Homozygote; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Risk; Squamous Cell Carcinoma of Head and Neck; Thymine | 2014 |
The axis inhibition protein 2 polymorphisms and non-syndromic orofacial clefts susceptibility in a Chinese Han population.
Topics: Adenine; Axin Protein; Case-Control Studies; China; Chromosome Mapping; Cleft Lip; Cleft Palate; Ethnicity; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Guanine; Haplotypes; Homozygote; Humans; Linkage Disequilibrium; Male; Polymorphism, Single Nucleotide; Thymine; Wnt Signaling Pathway | 2014 |
Dynamic comparison between Daan real-time PCR and Cobas TaqMan for quantification of HBV DNA levels in patients with CHB.
Topics: Adenine; Adolescent; Adult; Antiviral Agents; DNA, Viral; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Polymerase Chain Reaction; Prospective Studies; Real-Time Polymerase Chain Reaction; Reproducibility of Results; Sensitivity and Specificity; Viral Load; Young Adult | 2014 |
Identification of genetic risk factors for maxillary lateral incisor agenesis.
Topics: Adenine; Anodontia; Axin Protein; Case-Control Studies; Cytosine; Ectodysplasins; Female; Fibroblast Growth Factors; Gene Frequency; Genetic Predisposition to Disease; Genotype; Guanine; Haplotypes; Humans; Incisor; Intracellular Signaling Peptides and Proteins; Linkage Disequilibrium; Male; Maxilla; Membrane Proteins; MSX1 Transcription Factor; Nerve Tissue Proteins; Odontogenesis; PAX9 Transcription Factor; Polymorphism, Single Nucleotide; Risk Factors; Thymine; Tooth, Deciduous; Transforming Growth Factor alpha; Wnt Proteins | 2014 |
Generation of a human hepatoma cell line supporting efficient replication of a lamivudine resistant hepatitis B virus.
Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Guanine; Hep G2 Cells; Hepatitis B virus; Hepatocytes; Humans; Lamivudine; Organophosphonates; Tenofovir; Virus Replication | 2014 |
Overoxidized polyimidazole/graphene oxide copolymer modified electrode for the simultaneous determination of ascorbic acid, dopamine, uric acid, guanine and adenine.
Topics: Adenine; Ascorbic Acid; Biosensing Techniques; Dopamine; Electrochemical Techniques; Electrodes; Graphite; Guanine; Imidazoles; Limit of Detection; Oxidation-Reduction; Polymers; Uric Acid | 2014 |
Coupled-cluster and density functional theory studies of the electronic 0-0 transitions of the DNA bases.
Topics: Adenine; Cytosine; DNA; Guanine; Quantum Theory; Thymine | 2014 |
A miRNA-binding-site SNP of MSX1 is Associated with NSOC Susceptibility.
Topics: 3' Untranslated Regions; 5' Flanking Region; Adenine; Case-Control Studies; Cleft Lip; Cleft Palate; Gene Frequency; Genetic Predisposition to Disease; Genetic Variation; Genotype; Guanine; Humans; MicroRNAs; MSX1 Transcription Factor; Polymorphism, Single Nucleotide; Risk Factors | 2014 |
Revisiting the TALE repeat.
Topics: Adenine; Amino Acid Sequence; Binding Sites; DNA; DNA-Binding Proteins; Guanine; Molecular Dynamics Simulation; Molecular Sequence Data; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary | 2014 |
The role of autophagy induced by pemetrexed in lung adenocarcinoma cells.
Topics: Adenine; Adenocarcinoma; Adenocarcinoma of Lung; Annexin A5; Antimetabolites, Antineoplastic; Apoptosis; Autophagy; Cell Line, Tumor; Cell Survival; Glutamates; Guanine; Humans; Lung Neoplasms; Pemetrexed; Poly(ADP-ribose) Polymerases; Thymidylate Synthase | 2014 |
Successful withdrawal of antiviral treatment in kidney transplant recipients with chronic hepatitis B viral infection.
Topics: Adenine; Adult; Alanine Transaminase; Antiviral Agents; DNA, Viral; Female; Follow-Up Studies; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Immunosuppressive Agents; Kidney Transplantation; Lamivudine; Male; Middle Aged; Organophosphonates; Retrospective Studies; Telbivudine; Thymidine; Time Factors; Virus Activation; Withholding Treatment | 2014 |
[Diagnosis and treatment of chronic hepatitis B and D. Hungarian national consensus guideline].
Topics: Adenine; Antiviral Agents; Consensus; Drug Administration Schedule; Drug Therapy, Combination; Evidence-Based Medicine; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Hepatitis D, Chronic; Hepatitis Delta Virus; Humans; Hungary; Interferon-alpha; Lamivudine; Liver Neoplasms; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Tenofovir | 2014 |
Polymorphisms of +2836 G>A in the apoE gene are strongly associated with the susceptibility to essential hypertension in the Chinese Hui population.
Topics: Adenine; Apolipoproteins E; Asian People; Essential Hypertension; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Guanine; Humans; Hypertension; Polymorphism, Single Nucleotide | 2014 |
Association study of c.910A>G and c.1686C>G polymorphisms in XRCC1 gene with risk of hepatocellular carcinoma in the Chinese population.
Topics: Adenine; Aged; Asian People; Carcinoma, Hepatocellular; Case-Control Studies; Cytosine; DNA-Binding Proteins; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Guanine; Humans; Liver Neoplasms; Male; Middle Aged; Polymorphism, Single Nucleotide; Risk Factors; X-ray Repair Cross Complementing Protein 1 | 2014 |
Computational modeling of photoexcitation in DNA single and double strands.
Topics: Adenine; Base Pairing; Cytosine; DNA; DNA, Single-Stranded; Electrons; Energy Transfer; Guanine; Hydrogen Bonding; Models, Theoretical; Nucleic Acid Conformation; Photochemical Processes; Thymine; Uracil | 2015 |
Tumor necrosis factor-α and oral inflammation in patients with Crohn disease.
Topics: Adenine; Adult; Age Factors; Alleles; Case-Control Studies; Crohn Disease; Female; Genetic Variation; Genotype; Gingival Hemorrhage; Gingival Hyperplasia; Guanine; Haplotypes; Humans; Hyperplasia; Male; Middle Aged; Mouth Mucosa; Periodontal Attachment Loss; Periodontal Pocket; Periodontitis; Polymorphism, Single Nucleotide; Risk Factors; Sex Factors; Smoking; Tumor Necrosis Factor-alpha | 2014 |
Commentary: tenofovir is superior to entecavir in HBeAg-positive chronic hepatitis B patients.
Topics: Adenine; Antiviral Agents; Female; Guanine; Hepatitis B, Chronic; Humans; Male; Organophosphonates; Tenofovir | 2014 |
Commentary: tenofovir is superior to entecavir in HBeAg-positive chronic hepatitis B patients--authors' reply.
Topics: Adenine; Antiviral Agents; Female; Guanine; Hepatitis B, Chronic; Humans; Male; Organophosphonates; Tenofovir | 2014 |
An evaluation of selective deprotection conditions for the synthesis of RNA on a light labile solid support.
Topics: Adenine; Chromatography, Thin Layer; Cytosine; Guanine; Nucleosides; Oligonucleotides; RNA; Uracil | 2014 |
Effects of entecavir on peripheral blood lymphocyte profiles in chronic hepatitis B patients with suboptimal responses to adefovir.
Topics: Adenine; Antiviral Agents; B-Lymphocytes; Case-Control Studies; CD4-Positive T-Lymphocytes; DNA, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Organophosphonates; Tumor Necrosis Factor Receptor Superfamily, Member 7; Viral Load | 2014 |
Proton transfer induced SOMO-to-HOMO level switching in one-electron oxidized A-T and G-C base pairs: a density functional theory study.
Topics: Adenine; Base Pairing; Cytosine; Electrons; Guanine; Oxidation-Reduction; Protons; Quantum Theory; Thymine | 2014 |
Functional Significance of MMP3 and TIMP2 Polymorphisms in Cleft Lip/Palate.
Topics: Adenine; Alleles; Cell Line, Tumor; Cleft Lip; Cleft Palate; Cytosine; Guanine; Haplotypes; Humans; Matrix Metalloproteinase 3; NF-kappa B; Polymorphism, Genetic; Promoter Regions, Genetic; Protease Inhibitors; Thymine; Tissue Inhibitor of Metalloproteinase-2; Transcription, Genetic | 2014 |
Cd hyperfine interactions in DNA bases and DNA of mouse strains infected with Trypanosoma cruzi investigated by perturbed angular correlation spectroscopy and ab initio calculations.
Topics: Adenine; Animals; Cadmium; Cations, Divalent; Chagas Disease; Coordination Complexes; Cytosine; DNA; Guanine; Mice; Species Specificity; Thymine; Trypanosoma cruzi | 2014 |
Letter: Treatment of HBeAg+ chronic hepatitis B--is tenofovir truly superior to entecavir?
Topics: Adenine; Antiviral Agents; Female; Guanine; Hepatitis B, Chronic; Humans; Male; Organophosphonates; Tenofovir | 2014 |
Letter: Treatment of HBeAg+ chronic hepatitis B--is tenofovir truly superior to entecavir? Authors' reply.
Topics: Adenine; Antiviral Agents; Female; Guanine; Hepatitis B, Chronic; Humans; Male; Organophosphonates; Tenofovir | 2014 |
Raman spectroscopic evaluation of DNA adducts of a platinum containing anticancer drug.
Topics: Adenine; Animals; Antineoplastic Agents; Carboplatin; Cattle; Cisplatin; Cross-Linking Reagents; DNA; DNA Adducts; Guanine; Humans; Neoplasms; Nucleic Acid Conformation; Platinum; Protein Structure, Secondary; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Thymus Gland | 2014 |
Fragmentation of the adenine and guanine molecules induced by electron collisions.
Topics: Adenine; DNA; DNA Damage; Electrons; Guanine; Models, Chemical; Nucleotides | 2014 |
Coupling between hydrogen atoms transfer and stacking interaction in adenine-thymine/guanine-cytosine complexes: a theoretical study.
Topics: Adenine; Base Pairing; Cytosine; Guanine; Hydrogen; Hydrogen Bonding; Models, Theoretical; Molecular Conformation; Thermodynamics; Thymine | 2014 |
Does tautomerization of FapyG influence its mutagenicity?
Topics: Adenine; DNA; DNA Damage; Guanine; Mutation; Oxidation-Reduction; Pyrimidines; Thymine | 2014 |
Graphene sculpturene nanopores for DNA nucleobase sensing.
Topics: Adenine; Cytosine; DNA; Electrochemical Techniques; Graphite; Guanine; Nanopores; Nanotubes, Carbon; Probability; Sequence Analysis, DNA; Thymine | 2014 |
Coexistence of HBsAg and HBsAb in a difficult-to-treat chronic hepatitis B: loss of HBsAg with entecavir plus tenofovir combination.
Topics: Adenine; Antiviral Agents; Drug Therapy, Combination; Guanine; Hepatitis B Antibodies; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Organophosphonates; Recombinant Proteins; Tenofovir; Treatment Failure; Treatment Outcome; Viral Load | 2014 |
New nucleos(t)ide analogue monoprophylaxis after cessation of hepatitis B immunoglobulin is effective against hepatitis B recurrence.
Topics: Adenine; Adult; Cohort Studies; Female; Follow-Up Studies; Graft Rejection; Graft Survival; Guanine; Hepatitis B, Chronic; Humans; Immunoglobulins; Immunosuppressive Agents; Liver Cirrhosis; Liver Transplantation; Male; Organophosphonates; Prospective Studies; Recurrence; Retreatment; Risk Assessment; Statistics, Nonparametric; Tenofovir; Transplantation Immunology; Treatment Outcome | 2014 |
Novel complex disease allele mutations in cleidocranial dysplasia patients.
Topics: Adenine; Alleles; Amino Acid Sequence; Asparagine; Aspartic Acid; Case-Control Studies; Cleidocranial Dysplasia; Conserved Sequence; Core Binding Factor Alpha 1 Subunit; Cytosine; Exons; Female; Guanine; Humans; Leucine; Male; Mutation, Missense; Proline; Protein Conformation; Thymine; Tooth, Supernumerary | 2014 |
IL-18 gene polymorphisms in aphthous stomatitis vs. Behçet's disease in a cohort of Egyptian patients.
Topics: Adenine; Adolescent; Adult; Behcet Syndrome; Case-Control Studies; Cohort Studies; Cytosine; Egypt; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Guanine; Heterozygote; Homozygote; Humans; Interleukin-18; Male; Middle Aged; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Stomatitis, Aphthous; Young Adult | 2014 |
Understanding the interaction of DNA-RNA nucleobases with different ZnO nanomaterials.
Topics: Adenine; Binding Sites; Cytosine; DNA; Guanine; Models, Chemical; Models, Molecular; Nanostructures; Nanotubes; Quantum Dots; Quantum Theory; RNA; Surface Properties; Thermodynamics; Thymine; Uracil; Zinc Oxide | 2014 |
π-Cooperativity effect on the base stacking interactions in DNA: is there a novel stabilization factor coupled with base pairing H-bonds?
Topics: Adenine; Algorithms; Base Pairing; Dinucleoside Phosphates; DNA; Energy Transfer; Guanine; Hydrogen Bonding; Models, Molecular; Nucleic Acid Conformation; Protons; Thermodynamics | 2014 |
Adult onset Leigh syndrome with mitochondrial DNA 8344 A>G mutation.
Topics: Adenine; Adult; Age of Onset; Brain; Cognitive Dysfunction; Diffusion Magnetic Resonance Imaging; DNA, Mitochondrial; Female; Genetic Testing; Guanine; Humans; Leigh Disease; Memory Disorders; Muscle Weakness; Mutation; Optic Atrophies, Hereditary; Pedigree | 2014 |
Association study of single nucleotide polymorphisms of MAFB with non-syndromic cleft lip with or without cleft palate in a population in Heilongjiang Province, northern China.
Topics: Adenine; Case-Control Studies; Child; Child, Preschool; China; Cleft Lip; Cleft Palate; Cytosine; Ethnicity; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genetic Variation; Genotype; Guanine; Haplotypes; Humans; Leucine Zippers; Linkage Disequilibrium; MafB Transcription Factor; Male; Polymorphism, Single Nucleotide; Thymine | 2014 |
Investigation into drug-resistant mutations of HBV from 845 nucleoside/nucleotide analogue-naive Chinese patients with chronic HBV infection.
Topics: Adenine; Adult; Antiviral Agents; China; Clone Cells; Drug Resistance, Viral; Female; Gene Expression; Genotype; Guanine; Hep G2 Cells; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Microbial Sensitivity Tests; Middle Aged; Mutation; Organophosphonates; Phenotype; RNA-Directed DNA Polymerase; Sequence Analysis, DNA; Viral Proteins | 2015 |
Adefovir and lamivudine combination therapy in patients with entecavir-resistant chronic hepatitis B: antiviral responses and evolution of mutations.
Topics: Adenine; Adult; Aged; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Prospective Studies; Serum; Treatment Outcome; Viral Load | 2014 |
Highly sensitive and synergistic detection of guanine and adenine based on poly(xanthurenic acid)-reduced graphene oxide interface.
Topics: Adenine; Electrochemical Techniques; Graphite; Guanine; Xanthurenates | 2014 |
Overoxidized polypyrrole/graphene nanocomposite with good electrochemical performance as novel electrode material for the detection of adenine and guanine.
Topics: Adenine; Animals; Biosensing Techniques; Cattle; DNA; Electrochemical Techniques; Electrodes; Graphite; Guanine; Hydrogen-Ion Concentration; Limit of Detection; Microscopy, Electron, Scanning; Nanocomposites; Oxidation-Reduction; Polymers; Pyrroles; Reproducibility of Results; Spectroscopy, Fourier Transform Infrared | 2014 |
Antiviral therapy of chronic hepatitis B.
Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Carcinoma, Hepatocellular; Gene Products, pol; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver; Liver Cirrhosis; Liver Neoplasms; Organophosphonates; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Telbivudine; Tenofovir; Thymidine; Treatment Outcome; Virus Replication | 2014 |
Reduction of infectivity in chronic hepatitis B virus carriers among healthcare providers and pregnant women by antiviral therapy.
Topics: Adenine; Antiviral Agents; DNA, Viral; Female; Guanine; Health Personnel; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Infectious Disease Transmission, Professional-to-Patient; Infectious Disease Transmission, Vertical; Lamivudine; Organophosphonates; Pregnancy; Pregnancy Complications, Infectious; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine; Viral Load; Viremia | 2014 |
Mechanisms of hepatitis B virus resistance development.
Topics: Adenine; Amino Acid Substitution; Antiviral Agents; Deoxycytidine; Drug Resistance, Multiple, Viral; Emtricitabine; Guanine; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Organophosphonates; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Telbivudine; Tenofovir; Thymidine; Virus Replication | 2014 |
Hepatitis B virus drug resistance tools: one sequence, two predictions.
Topics: Adenine; Antiviral Agents; Base Sequence; Drug Resistance, Multiple, Viral; Genotype; Guanine; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Immune Evasion; Lamivudine; Microbial Sensitivity Tests; Organophosphonates; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Sequence Analysis, DNA; Telbivudine; Tenofovir; Thymidine | 2014 |
Virologic breakthrough in a patient with chronic hepatitis B by combination treatment with tenofovir disoproxil fumarate and entecavir.
Topics: Adenine; Amino Acid Substitution; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Middle Aged; Organophosphonates; Tenofovir; Treatment Outcome | 2014 |
Lipid peroxidation product 4-hydroxy-2-nonenal modulates base excision repair in human cells.
Topics: Adenine; Aldehydes; Cell Line; Cytosine; DNA Breaks, Single-Stranded; DNA Glycosylases; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; Guanine; Humans; Lipid Peroxidation | 2014 |
[Determination of four kinds of purines in deer fetus soft capsule by HPLC].
Topics: Adenine; Animals; Capsules; Chromatography, High Pressure Liquid; Deer; Fetus; Guanine; Hypoxanthine; Materia Medica; Purines; Quality Control; Reproducibility of Results; Xanthine | 2014 |
Silver- and gold-mediated nucleobase bonding.
Topics: Adenine; Cytosine; Gold; Guanine; Models, Molecular; Purines; Pyrimidines; Silver; Thermodynamics; Thymine | 2014 |
Treatment cessation in noncirrhotic, e-antigen negative chronic hepatitis B is safe and effective following prolonged anti-viral suppression with nucleosides/nucleotides.
Topics: Adenine; Adult; Antiviral Agents; Female; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Nucleosides; Nucleotides; Organophosphonates; Recurrence; Tenofovir; Withholding Treatment; Young Adult | 2014 |
Association of CCL5 and CCR5 gene polymorphisms with periodontitis in Taiwanese.
Topics: Adenine; Adult; Aged; Aggressive Periodontitis; Base Pairing; Case-Control Studies; Chemokine CCL5; Chronic Periodontitis; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Guanine; Humans; Male; Middle Aged; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Receptors, CCR5; Sequence Deletion; Taiwan; Young Adult | 2014 |
Efficacy and safety of tenofovir in a kidney transplant patient with chronic hepatitis B and nucleos(t)ide multidrug resistance: a case report.
Topics: Adenine; Antiviral Agents; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; Follow-Up Studies; Guanine; Hepatitis B, Chronic; Humans; Kidney Transplantation; Male; Middle Aged; Nucleosides; Nucleotides; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Outcome; Viral Load | 2014 |
Efficacy of entecavir-tenofovir combination therapy for chronic hepatitis B patients with multidrug-resistant strains.
Topics: Adenine; Adult; Aged; Antiviral Agents; Base Sequence; Cohort Studies; DNA, Viral; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates; Retrospective Studies; Reverse Transcriptase Inhibitors; Sequence Analysis, DNA; Tenofovir; Treatment Outcome; Viral Load; Young Adult | 2014 |
Incidence and predictors of hepatocellular carcinoma in Caucasian chronic hepatitis B patients receiving entecavir or tenofovir.
Topics: Adenine; Adult; Antiviral Agents; Carcinoma, Hepatocellular; Female; Follow-Up Studies; Greece; Guanine; Hepatitis B, Chronic; Humans; Incidence; Liver Neoplasms; Male; Middle Aged; Netherlands; Organophosphonates; Retrospective Studies; Reverse Transcriptase Inhibitors; Risk Factors; Spain; Tenofovir; Time Factors; Turkey; White People | 2015 |
[Retrospective analysis of the efficacy and safety of anti-hepatitis B virus drugs taken during pregnancy in women from the Guangdong Province].
Topics: Adenine; Antiviral Agents; Female; Guanine; Hepatitis B; Hepatitis B virus; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Male; Mothers; Organophosphonates; Pregnancy; Retrospective Studies; Telbivudine; Thymidine; Time Factors | 2014 |
Structure-wise discrimination of adenine and guanine by proteins on the basis of their nonbonded interactions.
Topics: Adenine; Guanine; Ligands; Molecular Structure; Nuclear Weapons; Proteins | 2015 |
Excitation of nucleobases from a computational perspective II: dynamics.
Topics: Adenine; Cytosine; Electrons; Energy Transfer; Guanine; Models, Theoretical; Molecular Dynamics Simulation; Photochemical Processes; Quantum Theory; Thymine; Ultraviolet Rays; Uracil | 2015 |
Determination of atropine sulfate using a novel sensitive DNA-biosensor based on its interaction on a modified pencil graphite electrode.
Topics: Adenine; Atropine; Biosensing Techniques; DNA; Electrochemical Techniques; Electrodes; Graphite; Guanine; Humans; Nanotubes, Carbon; Oxidation-Reduction; Titanium | 2015 |
Calculations of pKa's and redox potentials of nucleobases with explicit waters and polarizable continuum solvation.
Topics: Adenine; Cations; Cytosine; Guanine; Hydrogen Bonding; Hydrogen-Ion Concentration; Models, Chemical; Models, Genetic; Molecular Structure; Oxidation-Reduction; Protons; Solvents; Thymine; Uracil; Water | 2015 |
Metal-organic frameworks and β-cyclodextrin-based composite electrode for simultaneous quantification of guanine and adenine in a lab-on-valve manifold.
Topics: Adenine; Animals; Beer; beta-Cyclodextrins; Blood; Cattle; Electrochemical Techniques; Electrodes; Food Analysis; Guanine; Meat; Organometallic Compounds; Sensitivity and Specificity; Urine | 2014 |
The incidence of hepatocellular carcinoma is reduced in patients with chronic hepatitis B on long-term nucleos(t)ide analogue therapy.
Topics: Adenine; Adult; Antiviral Agents; Canada; Carcinoma, Hepatocellular; Female; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Incidence; Lamivudine; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Nucleosides; Organophosphonates; Retrospective Studies; Risk Factors; Telbivudine; Tenofovir; Thymidine | 2014 |
Long-term outcomes of two rescue therapies in lamivudine-refractory patients with chronic hepatitis B: combined lamivudine and adefovir, and 1-mg entecavir.
Topics: Adenine; Adult; Aged; Alanine Transaminase; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Retrospective Studies; Treatment Outcome | 2014 |
Associations of apolipoprotein E and low-density lipoprotein receptor-related protein 5 polymorphisms with dyslipidemia and generalized aggressive periodontitis in a Chinese population.
Topics: Adenine; Adolescent; Adult; Aggressive Periodontitis; Apolipoproteins E; Blood Glucose; China; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cytosine; Dyslipidemias; Female; Genotype; Guanine; Haplotypes; Humans; Low Density Lipoprotein Receptor-Related Protein-5; Male; Middle Aged; Periodontal Index; Polymorphism, Genetic; Thymine; Young Adult | 2015 |
Characterization of the mutagenic spectrum of 4-nitroquinoline 1-oxide (4-NQO) in Aspergillus nidulans by whole genome sequencing.
Topics: 4-Nitroquinoline-1-oxide; Adenine; Aspergillus nidulans; DNA Damage; Genome, Fungal; Guanine; High-Throughput Nucleotide Sequencing; Mutagenesis; Phenotype; Point Mutation; Sequence Analysis, DNA | 2014 |
Uncovering the polymerase-induced cytotoxicity of an oxidized nucleotide.
Topics: Adenine; Base Pairing; Catalytic Domain; Crystallography, X-Ray; Cytosine; Cytotoxins; Deoxyguanine Nucleotides; DNA; DNA Damage; DNA Polymerase beta; DNA Repair; DNA Replication; Guanine; Humans; Hydrogen Bonding; Kinetics; Models, Molecular; Molecular Conformation; Mutagenesis; Neoplasms; Oxidation-Reduction; Oxidative Stress; Static Electricity; Substrate Specificity; Time Factors | 2015 |
Structure-guided U2AF65 variant improves recognition and splicing of a defective pre-mRNA.
Topics: Adenine; Alternative Splicing; Binding Sites; Crystallography, X-Ray; Escherichia coli; Genetic Variation; Guanine; Humans; Molecular Conformation; Mutation; Nuclear Proteins; Protein Binding; Protein Engineering; Ribonucleoproteins; RNA; Splicing Factor U2AF; Uracil | 2014 |
Enamelin/ameloblastin gene polymorphisms in autosomal amelogenesis imperfecta among Syrian families.
Topics: Adenine; Amelogenesis Imperfecta; Amino Acid Sequence; Case-Control Studies; Child; Child, Preschool; Codon; Dental Enamel Proteins; Exons; Extracellular Matrix Proteins; Female; Guanine; Heterozygote; Homozygote; Humans; INDEL Mutation; Introns; Male; Pedigree; Phenotype; Polymorphism, Genetic; Sequence Deletion; Syria | 2011 |
Loss of loop adenines alters human telomere d[AG3(TTAG3)3] quadruplex folding.
Topics: Adenine; DNA Damage; G-Quadruplexes; Guanine; Humans; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Potassium; Telomere | 2014 |
Tenofovir-induced Fanconi syndrome in chronic hepatitis B monoinfected patients that reverted after tenofovir withdrawal.
Topics: Adenine; Antiviral Agents; Fanconi Syndrome; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates; Tenofovir; Treatment Outcome; Viral Load; Withholding Treatment | 2014 |
Association of BMP4 polymorphisms with non-syndromic cleft lip with or without cleft palate and isolated cleft palate in Latvian and Lithuanian populations.
Topics: Adenine; Bone Morphogenetic Protein 4; Case-Control Studies; Cleft Lip; Cleft Palate; Cytosine; Exons; Female; Gene Frequency; Genetic Linkage; Genetic Markers; Genotype; Guanine; Haplotypes; Humans; Introns; Latvia; Linkage Disequilibrium; Lithuania; Male; Polymorphism, Single Nucleotide; Thymine | 2014 |
Do we need more nucleos(t)ide analogs for the treatment of chronic hepatitis B?
Topics: Adenine; Antiviral Agents; Female; Guanine; Hepatitis B, Chronic; Humans; Male; Organophosphonates | 2015 |
Origin of life. From hell on Earth, life's building blocks.
Topics: Adenine; Cytosine; Earth, Planet; Evolution, Chemical; Formamides; Guanine; Hot Temperature; Meteoroids; Origin of Life; Pressure; Radiation, Ionizing; RNA; Uracil | 2014 |
[Tenofovir rescue therapy for chronic hepatitis B patients after suboptimal response to treatment with lamivudine plus adefovir dipivoxil].
Topics: Adenine; Adult; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Organophosphonates; Retrospective Studies; Tenofovir; Treatment Failure; Treatment Outcome | 2014 |
Early childhood caries is associated with genetic variants in enamel formation and immune response genes.
Topics: Adenine; Amelogenesis; Arachidonate 15-Lipoxygenase; Child, Preschool; Cross-Sectional Studies; Cytosine; Dental Caries; Dental Enamel Proteins; Epistasis, Genetic; Extracellular Matrix Proteins; Feeding Behavior; Female; Gene-Environment Interaction; Genes, MHC Class II; Genetic Markers; Genetic Variation; Guanine; Humans; Kallikreins; Lactoferrin; Male; Polymorphism, Genetic; Thymine | 2015 |
Deprotonated purine dissociation: experiments, computations, and astrobiological implications.
Topics: Adenine; Anions; Carbodiimides; Computer Simulation; Cyanamide; Cyanates; Cyanides; Exobiology; Guanine; Hydrogen Cyanide; Models, Chemical; Molecular Structure; Protons; Purines; Tandem Mass Spectrometry | 2015 |
Expanding the phenotypic expression of Sonic Hedgehog mutations beyond holoprosencephaly.
Topics: Adenine; Cysteine; Female; Gene Expression; Guanine; Hedgehog Proteins; Holoprosencephaly; Humans; Infant; Male; Mutation; Pedigree; Penetrance; Phenotype; Tyrosine | 2015 |
RAGE gene polymorphism and environmental factor in the risk of oral cancer.
Topics: Adenine; Areca; Base Pairing; Base Sequence; Carcinogenesis; Case-Control Studies; Cytosine; Female; Gene Frequency; Gene-Environment Interaction; Genetic Predisposition to Disease; Genetic Variation; Glycation End Products, Advanced; Glycine; Guanine; Haplotypes; Humans; Male; Middle Aged; Mouth Neoplasms; Neoplasm Staging; Polymorphism, Single Nucleotide; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Risk Factors; Sequence Deletion; Serine; Thymine; Tobacco Use | 2015 |
Electrocatalytic activity of molybdenum disulfide nanosheets enhanced by self-doped polyaniline for highly sensitive and synergistic determination of adenine and guanine.
Topics: Adenine; Aniline Compounds; Catalysis; Disulfides; Electrochemical Techniques; Guanine; Molybdenum; Nanostructures; Sensitivity and Specificity | 2015 |
Association of single-nucleotide polymorphisms in the IRF6 gene with non-syndromic cleft lip with or without cleft palate in the Xinjiang Uyghur population.
Topics: 5' Flanking Region; 5' Untranslated Regions; Adenine; Case-Control Studies; Cleft Lip; Cleft Palate; Cytosine; Exons; Gene Frequency; Genes, Dominant; Genes, Recessive; Genetic Predisposition to Disease; Genotype; Guanine; Haplotypes; Humans; Infant; Interferon Regulatory Factors; Introns; Isoleucine; Linkage Disequilibrium; Mutation, Missense; Polymorphism, Single Nucleotide; Serine; Valine | 2015 |
A molecular view of cisplatin's mode of action: interplay with DNA bases and acquired resistance.
Topics: Adenine; Antineoplastic Agents; Cisplatin; DNA Adducts; Glutathione; Guanine; Models, Molecular; Nucleic Acid Conformation; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; X-Ray Absorption Spectroscopy | 2015 |
DNA bases assembled on the Au(110)/electrolyte interface: a combined experimental and theoretical study.
Topics: Adenine; Adsorption; Computer Simulation; Cytosine; DNA; Electric Capacitance; Electrodes; Electrolytes; Gold; Guanine; Hydrogen-Ion Concentration; Microscopy, Scanning Tunneling; Models, Chemical; Protons; Surface Properties; Thymine | 2015 |
New size-expanded RNA nucleobase analogs: a detailed theoretical study.
Topics: Adenine; Base Pairing; Cytosine; Guanine; Models, Molecular; RNA; Spectrometry, Fluorescence; Uracil | 2015 |
Electrochemical determination of the anticancer drug taxol at a ds-DNA modified pencil-graphite electrode and its application as a label-free electrochemical biosensor.
Topics: Adenine; Antineoplastic Agents, Phytogenic; Biosensing Techniques; DNA; Electrochemical Techniques; Electrodes; Graphite; Guanine; Humans; Oxidation-Reduction; Paclitaxel | 2015 |
Determination of guanine and adenine by high-performance liquid chromatography with a self-fabricated wall-jet/thin-layer electrochemical detector at a glassy carbon electrode.
Topics: Adenine; Adsorption; Chromatography, High Pressure Liquid; DNA; Electrochemical Techniques; Electrodes; Graphite; Guanine | 2015 |
Synthesis of novel 2',3'-difluorinated 5'-deoxythreosyl phosphonic acid nucleosides as antiviral agents.
Topics: Acetates; Adenine; Anti-HIV Agents; Benzophenones; Chromatography, Thin Layer; Drug Design; Glyceraldehyde; Guanine; HIV Infections; Humans; Hydrogen; Leukocytes, Mononuclear; Magnetic Resonance Spectroscopy; Nucleosides; Phosphonoacetic Acid; Phosphorous Acids; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Sulfonamides | 2015 |
HBV carrying drug-resistance mutations in chronically infected treatment-naive patients.
Topics: Adenine; Antibodies, Viral; Antiviral Agents; Brazil; DNA, Viral; Drug Resistance, Viral; Gene Products, pol; Genotype; Guanine; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Microbial Sensitivity Tests; Mutation; Organophosphonates; Retrospective Studies; Sequence Analysis, DNA; Tenofovir; Virus Replication | 2015 |
Monitoring translocation of multisubunit RNA polymerase along the DNA with fluorescent base analogues.
Topics: 2-Aminopurine; Adenine; DNA; DNA-Directed RNA Polymerases; Escherichia coli; Fluorescence; Guanine; Molecular Biology; Molecular Structure; Oligonucleotides; Spectrometry, Fluorescence; Transcription, Genetic; Xanthopterin | 2015 |
Low-dose short-term hepatitis B immunoglobulin with high genetic barrier antivirals: the ideal post-transplant hepatitis B virus prophylaxis?
Topics: Adenine; Adult; Antiviral Agents; Carcinoma, Hepatocellular; Cohort Studies; Drug Resistance, Viral; Drug Therapy, Combination; Female; Follow-Up Studies; Guanine; Hepatitis B; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Immunoglobulins; Lamivudine; Liver Transplantation; Male; Middle Aged; Organophosphonates; Prospective Studies; Recurrence; Tenofovir | 2015 |
2-Thiouracil deprived of thiocarbonyl function preferentially base pairs with guanine rather than adenine in RNA and DNA duplexes.
Topics: Adenine; Base Pairing; Circular Dichroism; DNA; Guanine; Models, Chemical; Models, Molecular; Nucleic Acid Conformation; Nucleic Acid Denaturation; Nucleic Acid Heteroduplexes; RNA; Thermodynamics; Thiouracil; Thiouridine | 2015 |
Comparison of the efficacies of entecavir 0.5 and 1.0 mg combined with adefovir in patients with chronic hepatitis B who had failed on prior nucleos(t)ide analogue treatments.
Topics: Adenine; Adult; Aged; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates; Republic of Korea; Retrospective Studies; Time Factors; Treatment Failure; Treatment Outcome; Viral Load; Young Adult | 2015 |
Analysis of HBV genotype, drug resistant mutations, and pre-core/basal core promoter mutations in Korean patients with acute hepatitis B.
Topics: Adenine; Adult; Aged; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Female; Genotype; Guanine; Hepatitis B; Hepatitis B Core Antigens; Hepatitis B virus; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Promoter Regions, Genetic; Prospective Studies; Republic of Korea; Viral Core Proteins; Virus Replication | 2015 |
Tenofovir rescue regimen following prior suboptimal response to entecavir and adefovir combination therapy in chronic hepatitis B patients exposed to multiple treatment failures.
Topics: Adenine; Aged; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; High-Throughput Nucleotide Sequencing; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; ROC Curve; Tenofovir; Treatment Failure; Treatment Outcome | 2015 |
Interaction of Zn(2+) ions with single-stranded polyU and polyC in neutral solutions.
Topics: Adenine; Cations; Cytosine; Freezing; Guanine; Hydrogen-Ion Concentration; Solutions; Spectrum Analysis; Temperature; Uracil; Zinc | 2015 |
Dental Abnormalities Caused by Novel Compound Heterozygous CTSK Mutations.
Topics: Adenine; Adult; Alleles; Alveolar Process; Amino Acid Sequence; Animals; Cathepsin K; Chlorocebus aethiops; Codon, Terminator; Conserved Sequence; COS Cells; Cysteine; Dental Cementum; Guanine; Heterozygote; Humans; Male; Models, Genetic; Mutation, Missense; Pedigree; Phenol; Pycnodysostosis; Radiography, Panoramic; Tooth Abnormalities; Tryptophan; Tyrosine; X-Ray Microtomography | 2015 |
Hybridisation potential of 1',3'-Di-O-methylaltropyranoside nucleic acids.
Topics: Adenine; Cytosine; DNA; Guanine; Nucleic Acid Denaturation; Nucleic Acid Hybridization; Nucleic Acids; Oligonucleotides; RNA, Small Interfering; Sugar Alcohols; Thermodynamics; Uracil | 2015 |
Clinical course of chronic hepatitis B patients receiving nucleos(t)ide analogues after virological breakthrough during monotherapy with lamivudine.
Topics: Adenine; Adult; Aged; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Retrospective Studies; Tenofovir; Treatment Outcome; Viral Load; Viral Matrix Proteins; Young Adult | 2015 |
Gold nanoparticle/polymer nanocomposite for highly sensitive drug-DNA interaction.
Topics: Adenine; DNA; Electrochemistry; Ferrous Compounds; Gold; Guanine; Metal Nanoparticles; Mitomycin; Nanocomposites; Oxidation-Reduction; Polymerization; Polyvinyls | 2015 |
[Pharmacoeconomic evaluation of treatments based on antiretrovirals for HBeAg-negative chronic hepatitis B].
Topics: Adenine; Antiviral Agents; China; Cost-Benefit Analysis; Economics, Pharmaceutical; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Organophosphonates; Polyethylene Glycols; Quality-Adjusted Life Years; Recombinant Proteins | 2015 |
Excision of Expanded GAA Repeats Alleviates the Molecular Phenotype of Friedreich's Ataxia.
Topics: Aconitate Hydratase; Adenine; Alleles; Cell Differentiation; Endodeoxyribonucleases; Fibroblasts; Friedreich Ataxia; Genetic Therapy; Guanine; Heterozygote; Humans; Induced Pluripotent Stem Cells; Introns; K562 Cells; Neurons; Phenotype; RNA, Messenger; Trinucleotide Repeat Expansion; Zinc Fingers | 2015 |
Limited hepatitis B immunoglobulin with potent nucleos(t)ide analogue is a cost-effective prophylaxis against hepatitis B virus after liver transplantation.
Topics: Adenine; Adult; Aged; Antiviral Agents; Cost-Benefit Analysis; Drug Costs; Female; Graft Survival; Guanine; Hepatitis B; Hepatitis B Surface Antigens; Humans; Immunoglobulins; Liver Transplantation; Male; Middle Aged; Organophosphonates; Retrospective Studies; Tenofovir; Treatment Outcome; United States | 2015 |
Measurements of single nucleotide electronic states as nanoelectronic fingerprints for identification of DNA nucleobases, their protonated and unprotonated states, isomers, and tautomers.
Topics: Adenine; Cytosine; Electromagnetic Phenomena; Guanine; Hydrogen-Ion Concentration; Isomerism; Models, Chemical; Models, Genetic; Molecular Structure; Nucleotides; Protons; Quantum Theory; Spectrum Analysis; Thymine | 2015 |
Differential repair of etheno-DNA adducts by bacterial and human AlkB proteins.
Topics: Adenine; AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; AlkB Homolog 3, Alpha-Ketoglutarate-Dependent Dioxygenase; Bacteria; Bacterial Proteins; Cytosine; Dioxygenases; DNA; DNA Adducts; DNA Glycosylases; DNA Repair; DNA Repair Enzymes; DNA, Single-Stranded; Escherichia coli; Escherichia coli Proteins; Guanine; Humans; Mixed Function Oxygenases; Mycobacterium tuberculosis; Rhizobium etli; Streptomyces; Substrate Specificity; Xanthomonas campestris | 2015 |
A graphene field-effect transistor as a molecule-specific probe of DNA nucleobases.
Topics: Adenine; Adsorption; Base Sequence; Cytosine; DNA; DNA Probes; Graphite; Guanine; Sequence Analysis, DNA; Thymine; Transistors, Electronic | 2015 |
Nucleobase modified neamines with a lysine as a linker, their inhibition specificity for TAR-Tat derived from HIV-1.
Topics: Adenine; Cytosine; Framycetin; Guanine; HIV Long Terminal Repeat; HIV-1; Lysine; Molecular Structure; Structure-Activity Relationship; tat Gene Products, Human Immunodeficiency Virus; Thymine | 2015 |
Simultaneous Detection of 3-Nitrotyrosine and 3-Nitro-4-hydroxyphenylacetic Acid in Human Urine by Online SPE LC-MS/MS and Their Association with Oxidative and Methylated DNA Lesions.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenine; Adult; Chromatography, High Pressure Liquid; Chromatography, Liquid; Deoxyguanosine; Dimethylnitrosamine; DNA Methylation; Guanine; Humans; Limit of Detection; Middle Aged; Nitrophenols; Oxidation-Reduction; Phenylacetates; Solid Phase Extraction; Tandem Mass Spectrometry; Tyrosine; Young Adult | 2015 |
Early kidney injury during long-term adefovir dipivoxil therapy for chronic hepatitis B.
Topics: Acute Kidney Injury; Adenine; Adult; Antiviral Agents; beta 2-Microglobulin; Biomarkers; Case-Control Studies; Creatinine; Drug Substitution; Female; Glomerular Filtration Rate; Guanine; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates; Predictive Value of Tests; Prospective Studies; Retinol-Binding Proteins; Risk Factors; Time Factors; Treatment Outcome | 2015 |
Fragmentation mechanisms of cytosine, adenine and guanine ionized bases.
Topics: Adenine; Cations; Cytosine; Guanine; Molecular Structure; Quantum Theory | 2015 |
Structural Basis for the Inverted Repeat Preferences of mariner Transposases.
Topics: Adenine; Animals; Base Sequence; Crystallography, X-Ray; DNA; DNA-Binding Proteins; Drosophila; Gene Expression Regulation, Enzymologic; Guanine; Inverted Repeat Sequences; Models, Molecular; Molecular Sequence Data; Plasmids; Protein Conformation; Transposases | 2015 |
Clonal evolution of multidrug resistant hepatitis B virus during entecavir rescue therapy.
Topics: Adenine; Adult; Antiviral Agents; Clonal Evolution; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Genotype; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Viral Load | 2015 |
Impact of nucleos(t)ide analogue combination therapy on the estimated glomerular filtration rate in patients with chronic hepatitis B.
Topics: Adenine; Adult; Aged; Antiviral Agents; Drug Therapy, Combination; Female; Glomerular Filtration Rate; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Nucleosides; Nucleotides; Organophosphonates; Retrospective Studies; Telbivudine; Thymidine | 2015 |
IRF6 Is a Marker of Severity in Nonsyndromic Cleft Lip/Palate.
Topics: Adenine; Biomarkers, Tumor; Case-Control Studies; Chromosome Mapping; Cleft Lip; Cleft Palate; Gene Frequency; Genetic Variation; Genome-Wide Association Study; Genotyping Techniques; Guanine; Haplotypes; Humans; Interferon Regulatory Factors; Linkage Disequilibrium; Mutation; Phenotype; Polymorphism, Single Nucleotide; Retrospective Studies; Thymine | 2015 |
A case of entecavir resistance which is developed after complete viral suppression during entecavir treatment for nucleoside-naive chronic hepatitis B.
Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Nucleosides; Organophosphonates; Remission Induction; Tenofovir | 2014 |
Response to potent anti-HBV agents in chronic hepatitis B and combined effect of HBV reverse transcriptase mutations.
Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Mutation; Organophosphonates; RNA-Directed DNA Polymerase; Tenofovir | 2015 |
Entecavir Combined With Adefovir Ameliorates Patients With Chronic Hepatitis B Who Fail to Respond to Nucleotide (Acid) Analog Monotherapy.
Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Drug Therapy, Combination; Female; Follow-Up Studies; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Liver Cirrhosis; Male; Middle Aged; Organophosphonates; Retrospective Studies; Risk Factors; Time Factors; Treatment Outcome | 2017 |
Nucleoside-Nucleotide Analog Combination Therapy Is Effective in Preventing Recurrent Hepatitis B After Liver Transplantation.
Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Immunoglobulins; Lamivudine; Liver Transplantation; Male; Middle Aged; Organophosphonates; Prospective Studies; Recurrence; Tenofovir | 2015 |
Tenofovir-based rescue therapy for chronic hepatitis B patients who had failed treatment with lamivudine, adefovir, and entecavir.
Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Multivariate Analysis; Organophosphonates; Tenofovir; Treatment Failure | 2015 |
Lactotransferrin Gene Polymorphism Associated with Caries Experience.
Topics: Adenine; Buffers; Child; Cytosine; Dental Caries; Dental Caries Susceptibility; Dental Plaque Index; DMF Index; Female; Fluorosis, Dental; Gene Frequency; Genotype; Gingivitis; Guanine; Humans; Hydrogen-Ion Concentration; Lactoferrin; Male; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Saliva; Secretory Rate | 2015 |
Prevalence and types of drug-resistant variants in Chinese patients with acute hepatitis B.
Topics: Adenine; Adult; Antiviral Agents; China; DNA, Viral; Drug Resistance, Viral; Female; Genetic Variation; Guanine; Hepatitis B; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation, Missense; Organophosphonates; Prevalence; RNA-Directed DNA Polymerase; Telbivudine; Thymidine; Time Factors; Young Adult | 2015 |
Effect of Methylation on the Properties of the H-Bridges in DNA. A Systematic Theoretical Study on the Couples of Base Pairs.
Topics: Adenine; Base Pairing; Cytosine; DNA; DNA Methylation; Guanine; Hydrogen; Hydrogen Bonding; Models, Chemical; Models, Genetic | 2015 |
CuFe2O4 magnetic nanocrystal clusters as a matrix for the analysis of small molecules by negative-ion matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
Topics: Adenine; Amino Acids; Copper; Cytosine; Fatty Acids; Ferrous Compounds; Guanine; Humans; Magnetite Nanoparticles; Peptides; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Steroids; Testosterone; Thymine | 2015 |
Morphological analyses and a novel de novo DLX3 mutation associated with tricho-dento-osseous syndrome in a Chinese family.
Topics: Absorptiometry, Photon; Adenine; Adult; Bone Density; China; Conserved Sequence; Craniofacial Abnormalities; Dental Enamel; Dental Enamel Hypoplasia; Dentin; Exons; Female; Guanine; Hair; Hair Diseases; Homeodomain Proteins; Humans; Imaging, Three-Dimensional; Introns; Microscopy, Confocal; Microscopy, Electron, Scanning; Mutation, Missense; Spectrometry, X-Ray Emission; Transcription Factors | 2015 |
An atlas of RNA base pairs involving modified nucleobases with optimal geometries and accurate energies.
Topics: Adenine; Base Pairing; Cytosine; Guanine; Molecular Structure; RNA; Uracil | 2015 |
Comparison of entecavir monotherapy and de novo lamivudine and adefovir combination therapy in HBeAg-positive chronic hepatitis B with high viral load: 48-week result.
Topics: Adenine; Adolescent; Adult; Alanine Transaminase; Antiviral Agents; Blood; DNA, Viral; Female; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Prospective Studies; Treatment Outcome; Viral Load; Young Adult | 2016 |
Design, Synthesis, and Evaluation of Anti-HBV Activity of Hybrid Molecules of Entecavir and Adefovir: Exomethylene Acycloguanine Nucleosides and Their Monophosphate Derivatives.
Topics: Adenine; Antiviral Agents; Drug Design; Guanine; Hep G2 Cells; Hepatitis B virus; Humans; In Vitro Techniques; Organophosphonates | 2015 |
Gum acacia mitigates genetic damage in adenine-induced chronic renal failure in rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenine; Animals; Comet Assay; Deoxyguanosine; DNA Damage; Guanine; Guanosine; Gum Arabic; Kidney Failure, Chronic; Kidney Function Tests; Male; Random Allocation; Rats, Wistar; Renal Agents | 2015 |
High-resolution Digital Mapping of N-Methylpurines in Human Cells Reveals Modulation of Their Induction and Repair by Nearest-neighbor Nucleotides.
Topics: Adenine; Cell Line; DNA Repair; Fibroblasts; Guanine; Humans; Sulfuric Acid Esters | 2015 |
Nucleotide carriers for anti-tumour actinomycin antibiotics.
Topics: Adenine; Antibiotics, Antineoplastic; Caffeine; Dactinomycin; DNA; Drug Carriers; Fluorescent Dyes; Folic Acid; Guanine; Nucleotides; Thymine | 2016 |
Synthesis and X-ray crystal structure of the dirhenium complex Re2(i-C3H7COO)4Cl2 and its interactions with the DNA purine nucleobases.
Topics: Adenine; Coordination Complexes; Crystallography, X-Ray; DNA; Guanine; Liposomes; Proton Magnetic Resonance Spectroscopy; Rhenium; Solubility; Spectrometry, Mass, Electrospray Ionization | 2015 |
Experimental and theoretical investigation effect of flavonols antioxidants on DNA damage.
Topics: Acridine Orange; Adenine; Antioxidants; Biosensing Techniques; DNA; DNA Damage; Electrochemical Techniques; Electrodes; Flavonols; Graphite; Guanine; Limit of Detection; Molecular Docking Simulation; Nucleic Acid Conformation | 2015 |
Substitution at rt269 in Hepatitis B Virus Polymerase Is a Compensatory Mutation Associated with Multi-Drug Resistance.
Topics: Adenine; Amino Acid Substitution; Antiviral Agents; Arabinofuranosyluracil; Cell Line, Tumor; Drug Resistance, Multiple, Viral; Gene Products, pol; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Microbial Sensitivity Tests; Models, Molecular; Organophosphonates; Tenofovir; Virus Replication | 2015 |
CRISPRscan: designing highly efficient sgRNAs for CRISPR-Cas9 targeting in vivo.
Topics: 3' Untranslated Regions; Adenine; Algorithms; Animals; Clustered Regularly Interspaced Short Palindromic Repeats; CRISPR-Cas Systems; Embryo, Nonmammalian; Female; Gene Expression Regulation; Gene Targeting; Genetic Engineering; Genome; Guanine; Mutation; RNA, Guide, Kinetoplastida; Xenopus; Zebrafish; Zebrafish Proteins | 2015 |
Mechanism of Adefovir, Tenofovir and Entecavir Resistance: Molecular Modeling Studies of How A Novel Anti-HBV Agent (FMCA) Can Overcome the Drug Resistance.
Topics: Adenine; Adenosine; Amino Acid Sequence; Antiviral Agents; Binding Sites; Catalytic Domain; Databases, Protein; Drug Resistance, Viral; Gene Products, pol; Guanine; Hepatitis B; Hepatitis B virus; HIV Reverse Transcriptase; Humans; Hydrogen Bonding; Molecular Dynamics Simulation; Molecular Sequence Data; Mutation; Organophosphonates; Sequence Alignment; Tenofovir | 2015 |
Simultaneous Determination of Adenine and Guanine Using Cadmium Selenide Quantum Dots-Graphene Oxide Nanocomposite Modified Electrode.
Topics: Adenine; Animals; Cadmium Compounds; DNA; Electrochemical Techniques; Electrodes; Fishes; Graphite; Guanine; Male; Nanocomposites; Nanotechnology; Oxides; Quantum Dots; Selenium Compounds; Spermatozoa | 2015 |
Expanded GAA repeats impede transcription elongation through the FXN gene and induce transcriptional silencing that is restricted to the FXN locus.
Topics: Adenine; Frataxin; Friedreich Ataxia; Gene Silencing; Genetic Loci; Guanine; Histones; Iron-Binding Proteins; Sequence Analysis, RNA; Transcription Elongation, Genetic; Trinucleotide Repeat Expansion | 2015 |
Toxicity prediction of PHDDs and phenols in the light of nucleic acid bases and DNA base pair interaction.
Topics: Adenine; Base Pairing; Cytosine; DNA; Environmental Pollutants; Guanine; Models, Chemical; Polychlorinated Dibenzodioxins; Quantitative Structure-Activity Relationship; Quantum Theory; Thermodynamics; Thymine; Uracil | 2015 |
Crystal structure of the Varkud satellite ribozyme.
Topics: Adenine; Catalytic Domain; Crystallography, X-Ray; Endoribonucleases; Evolution, Molecular; Fungal Proteins; Gene Expression; Guanine; Mitochondria; Molecular Docking Simulation; Mutation; Neurospora; Nucleic Acid Conformation; Phosphates; Plasmids; Protein Multimerization; Protein Structure, Secondary; Recombinant Proteins; RNA; RNA, Catalytic | 2015 |
Relative Binding Free Energies of Adenine and Guanine to Damaged and Undamaged DNA in Human DNA Polymerase η: Clues for Fidelity and Overall Efficiency.
Topics: Adenine; Catalytic Domain; DNA; DNA-Directed DNA Polymerase; Guanine; Humans; Hydrogen Bonding; Molecular Dynamics Simulation; Thermodynamics | 2015 |
Long-term follow-up of HBsAg-positive patients in Germany.
Topics: Adenine; Adult; Age Factors; Antiviral Agents; Carcinoma, Hepatocellular; DNA, Viral; Drug Therapy, Combination; Female; Follow-Up Studies; Germany; Guanine; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Male; Mass Screening; Middle Aged; Organophosphonates; Prognosis; Prospective Studies; Retrospective Studies; Telbivudine; Tenofovir; Thymidine; Time Factors; Turkey | 2016 |
Analysis of association among clinical features and shorter leukocyte telomere length in mitochondrial diabetes with m.3243A>G mitochondrial DNA mutation.
Topics: Adenine; Adolescent; Adult; Age of Onset; Aged; Deafness; Diabetes Mellitus, Type 2; DNA, Mitochondrial; Female; Genetic Association Studies; Guanine; Humans; Male; Middle Aged; Mitochondrial Diseases; Pedigree; Polymorphism, Single Nucleotide; Telomere; Young Adult | 2015 |
Management of entecavir-resistant chronic hepatitis B with adefovir-based combination therapies.
Topics: Adenine; Adult; Aged; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Viral Load; Young Adult | 2015 |
DFT Investigation of the Mechanism of Action of Organoiridium(III) Complexes As Anticancer Agents.
Topics: Adenine; Antineoplastic Agents; Coordination Complexes; Glutathione; Guanine; Hydrolysis; Iridium; Models, Chemical; Models, Molecular; NAD; Oxidation-Reduction | 2015 |
Insight into the Mechanism of the Initial Reaction of an OH Radical with DNA/RNA Nucleobases: A Computational Investigation of Radiation Damage.
Topics: Adenine; Computer Simulation; DNA; Guanine; Hydroxyl Radical; Kinetics; RNA; Thymine; Uracil | 2015 |
Entecavir plus tenofovir versus entecavir plus adefovir in chronic hepatitis B patients with a suboptimal response to lamivudine and adefovir combination therapy.
Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Odds Ratio; Organophosphonates; Real-Time Polymerase Chain Reaction; Retrospective Studies; Tenofovir; Viral Load | 2015 |
In situ electrochemical evaluation of dsDNA interaction with the anticancer drug danusertib nitrenium radical product using the DNA-electrochemical biosensor.
Topics: Adenine; Antineoplastic Agents; Benzamides; Biosensing Techniques; DNA; Electrochemistry; Free Radicals; Guanine; Molecular Structure; Nitrogen; Nucleic Acid Conformation; Oxidation-Reduction; Pyrazoles | 2016 |
A new microplatform based on titanium dioxide nanofibers/graphene oxide nanosheets nanocomposite modified screen printed carbon electrode for electrochemical determination of adenine in the presence of guanine.
Topics: Adenine; Carbon; Complex Mixtures; Conductometry; Equipment Design; Equipment Failure Analysis; Graphite; Guanine; Microelectrodes; Nanocomposites; Nanofibers; Oxides; Reproducibility of Results; Sensitivity and Specificity; Titanium | 2016 |
How the intercalation of phenanthroline affects the structure, energetics, and bond properties of DNA base pairs: theoretical study applied to adenine-thymine and guanine-cytosine tetramers.
Topics: Adenine; Base Pairing; Cytosine; DNA; Guanine; Molecular Structure; Phenanthrolines; Quantum Theory; Thermodynamics; Thymine | 2015 |
Comprehensive analysis of hospital-based prospective cohort reveals the unique effectiveness and safety for nucleos(t)ide analogues in HBV patients.
Topics: Adenine; Adult; Antiviral Agents; Female; Guanine; Hepatitis B, Chronic; Hospitalization; Humans; Lamivudine; Male; Organophosphonates; Prospective Studies; Telbivudine; Thymidine; Treatment Outcome | 2016 |
Epidemiology study of HBV genotypes and antiviral drug resistance in multi-ethnic regions from Western China.
Topics: Adenine; Adult; Antiviral Agents; China; DNA, Viral; Drug Resistance, Viral; Ethnicity; Female; Genotype; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Molecular Epidemiology; Mutation; Organophosphonates; Prevalence | 2015 |
Complete-active-space second-order perturbation theory (CASPT2//CASSCF) study of the dissociative electron attachment in canonical DNA nucleobases caused by low-energy electrons (0-3 eV).
Topics: Adenine; Cytosine; DNA; DNA Breaks; Electrons; Guanine; Hydrogen; Thermodynamics; Thymine; Uracil | 2015 |
Nephrotoxicity caused by oral antiviral agents in patients with chronic hepatitis B treated in a hospital for tropical diseases in Thailand.
Topics: Adenine; Adult; Antiviral Agents; Creatinine; Female; Follow-Up Studies; Guanine; Hepatitis B, Chronic; Hospitals; Humans; Incidence; Kidney Diseases; Lamivudine; Male; Middle Aged; Nephrons; Organophosphonates; Proportional Hazards Models; Retrospective Studies; Risk Assessment; Risk Factors; Telbivudine; Tenofovir; Thailand; Thymidine; Tropical Medicine | 2015 |
Simultaneous Determination of Dopamine, Uric Acid and Guanine at Polyadenine Film Modified Electrode.
Topics: Adenine; Carbon; Dopamine; Electrochemical Techniques; Electrodes; Guanine; Humans; Limit of Detection; Microscopy, Electron, Scanning; Oxidation-Reduction; Reproducibility of Results; Surface Properties; Uric Acid | 2015 |
A Study of π-π Stacking Interactions and Aromaticity in Polycyclic Aromatic Hydrocarbon/Nucleobase Complexes.
Topics: Adenine; Cytosine; Guanine; Polycyclic Aromatic Hydrocarbons; Quantum Theory; Thymine; Uracil | 2016 |
Structure and stereochemistry of the base excision repair glycosylase MutY reveal a mechanism similar to retaining glycosidases.
Topics: Adenine; Bacterial Proteins; Catalysis; Catalytic Domain; DNA Glycosylases; DNA Repair; Geobacillus stearothermophilus; Guanine; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Tyrosine | 2016 |
Ranking of Molecular Biomarker Interaction with Targeted DNA Nucleobases via Full Atomistic Molecular Dynamics.
Topics: Acetone; Adenine; Biomarkers; Biosensing Techniques; Cardiovascular Diseases; Cytosine; Diabetes Mellitus; DNA, Single-Stranded; Electrochemical Techniques; Ethanol; Exhalation; Guanine; Humans; Hydrochloric Acid; Hydrogen Sulfide; Molecular Dynamics Simulation; Pancreatitis, Chronic; Thermodynamics; Thymine | 2016 |
Synthesis, Antibacterial Activity, Interaction with Nucleobase and Molecular Docking Studies of 4-Formylbenzoic Acid Based Thiazoles.
Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Adenine; Anti-Bacterial Agents; Benzoates; Cytosine; DNA Topoisomerase IV; Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing); Gram-Negative Bacteria; Gram-Positive Bacteria; Guanine; Molecular Docking Simulation; Peptide Synthases; Quantum Theory; Stereoisomerism; Structure-Activity Relationship; Thermodynamics; Thiazoles; Thymine; Topoisomerase II Inhibitors | 2016 |
Off-treatment efficacy of 3-year nucleos(t)ide analogues in chronic hepatitis B patients.
Topics: Adenine; Adult; Alanine Transaminase; Antiviral Agents; Female; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Retrospective Studies; Telbivudine; Tenofovir; Thymidine; Treatment Outcome | 2016 |
Multidrug resistance protein 4 is a critical protein associated with the antiviral efficacy of nucleos(t)ide analogues.
Topics: Adenine; Adult; Antiviral Agents; Cell Line, Tumor; Drug Resistance, Viral; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Leukocytes, Mononuclear; Male; Middle Aged; Multidrug Resistance-Associated Proteins; Multivariate Analysis; Proportional Hazards Models; Treatment Failure; Verapamil | 2016 |
Reliable vibrational wavenumbers for C=O and N-H stretchings of isolated and hydrogen-bonded nucleic acid bases.
Topics: Adenine; Base Pairing; Cytosine; Dimerization; Guanine; Hydrogen; Hydrogen Bonding; Models, Molecular; Nitrogen; Nucleic Acids; Oxygen; Pyrimidinones; Spectrophotometry, Infrared; Thymine; Uracil | 2016 |
A 'bottom up', ab initio computational approach to understanding fundamental photophysical processes in nitrogen containing heterocycles, DNA bases and base pairs.
Topics: Adenine; Animals; Base Pairing; Cytosine; DNA; Guanine; Humans; Nitrogen; Thymine | 2016 |
[Drug-resistant mutations in hepatitis B virus found in chronic HBV carriers using PCR sequencing technology].
Topics: Adenine; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Genotype; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Mutation; Organophosphonates; Polymerase Chain Reaction; Telbivudine; Tenofovir; Thymidine | 2016 |
Profile of HBV polymerase gene mutations during entecavir treatment in patients with chronic hepatitis B.
Topics: Adenine; Adolescent; Adult; Alanine Transaminase; Antiviral Agents; Drug Resistance, Viral; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Viral Load; Young Adult | 2016 |
Resistance of ground glass hepatocytes to oral antivirals in chronic hepatitis B patients and implication for the development of hepatocellular carcinoma.
Topics: Adenine; Administration, Oral; Adolescent; Adult; Amino Acid Sequence; Antiviral Agents; Biopsy; Carcinoma, Hepatocellular; DNA, Circular; Drug Resistance, Viral; Fatty Liver; Female; Guanine; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Hepatocytes; Humans; Lamivudine; Liver; Liver Neoplasms; Male; Middle Aged; Necrosis; Organophosphonates; Protein Precursors; Sequence Deletion; Viral Load; Young Adult | 2016 |
A role for adenine nucleotides in the sensing mechanism to purine starvation in Leishmania donovani.
Topics: Adenine; Adenine Nucleotides; Guanine; Guanine Nucleotides; Leishmania donovani; Purine Nucleotides; Purines; Starvation | 2016 |
De novo entecavir+adefovir dipivoxil+lamivudine triple-resistance mutations resulting from sequential therapy with adefovir dipivoxil, and lamivudine.
Topics: Adenine; Adult; Antiviral Agents; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Retrospective Studies; Viral Proteins | 2016 |
Insights into RNA binding by the anticancer drug cisplatin from the crystal structure of cisplatin-modified ribosome.
Topics: Adenine; Anti-Bacterial Agents; Antineoplastic Agents; Binding Sites; Cisplatin; Coumarins; Crystallography, X-Ray; Guanine; Models, Molecular; Nucleic Acid Synthesis Inhibitors; Ribosomes; RNA, Ribosomal | 2016 |
Hepatitis B virus related cryoglobulinemic vasculitis: A multicentre open label study from the Gruppo Italiano di Studio delle Crioglobulinemie - GISC.
Topics: Adenine; Aged; Antiviral Agents; Cryoglobulinemia; Female; Guanine; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Italy; Lamivudine; Male; Middle Aged; Organophosphonates; Treatment Outcome; Vasculitis | 2016 |
Symmetry-adapted digital modeling II. The double-helix B-DNA.
Topics: Adenine; Crystallography, X-Ray; Cytosine; DNA, B-Form; Guanine; Models, Molecular; Nucleic Acid Conformation; Thymine | 2016 |
Stacking of purines in water: the role of dipolar interactions in caffeine.
Topics: Adenine; Caffeine; Guanine; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Nucleic Acid Conformation; Purines; Quantum Theory; Solutions; Temperature; Ultraviolet Rays; Water | 2016 |
Inflammation increases oxidative DNA damage repair and stimulates preneoplastic changes in colons of newborn rats.
Topics: Adenine; Animals; Animals, Newborn; Arachidonate 12-Lipoxygenase; Colon; Colonic Neoplasms; Cyclooxygenase 2; Cytosine; DNA Damage; DNA Repair; Escherichia coli; Guanine; Inflammation; Lipopolysaccharides; Oxidative Stress; Precancerous Conditions; Rats, Wistar; Salmonella typhimurium | 2016 |
Reaction electronic flux and its role in DNA intramolecular proton transfers.
Topics: Adenine; Algorithms; Cytosine; DNA; Electrons; Guanine; Imines; Isomerism; Models, Chemical; Models, Molecular; Molecular Structure; Protons; Static Electricity; Thymine | 2016 |
Cost-effectiveness analysis of tenofovir disoproxil fumarate for treatment of chronic hepatitis B in China.
Topics: Adenine; Antiviral Agents; Cost-Benefit Analysis; Female; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Male; Markov Chains; Organophosphonates; Quality-Adjusted Life Years; Telbivudine; Tenofovir; Thymidine; Treatment Outcome | 2016 |
Impact of FIB-4 index on hepatocellular carcinoma incidence during nucleos(t)ide analogue therapy in patients with chronic hepatitis B: An analysis using time-dependent receiver operating characteristic.
Topics: Adenine; Alanine Transaminase; Antiviral Agents; Aspartate Aminotransferases; Biomarkers; Carcinoma, Hepatocellular; Drug Therapy, Combination; Female; Follow-Up Studies; Guanine; Hepatitis B, Chronic; Humans; Incidence; Lamivudine; Liver Neoplasms; Male; Middle Aged; Multivariate Analysis; Organophosphonates; Phosphorous Acids; Platelet Count; Proportional Hazards Models; Risk Factors; ROC Curve; Time Factors | 2017 |
The efficacy of tenofovir-based therapy in patients showing suboptimal response to entecavir-adefovir combination therapy.
Topics: Adenine; Adult; Aged; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates; Polymerase Chain Reaction; Republic of Korea; Retrospective Studies; Tenofovir; Treatment Outcome | 2016 |
A five years study of antiviral effect of entecavir in Chinese chronic hepatitis B patients.
Topics: Adenine; Adult; Antiviral Agents; Asian People; China; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Time Factors; Treatment Outcome; Viral Load | 2016 |
Sequence-Specific Recognition of DNA by Proteins: Binding Motifs Discovered Using a Novel Statistical/Computational Analysis.
Topics: Adenine; Amino Acid Motifs; Amino Acids; Binding Sites; Computational Biology; Crystallography, X-Ray; Cytosine; Databases, Protein; DNA; DNA-Binding Proteins; Guanine; Models, Molecular; Nucleic Acid Conformation; Protein Binding; Protein Structure, Tertiary; Statistics as Topic; Thermodynamics; Thymine | 2016 |
The long-term efficacy of combining nucleos(t)ide analog and low-dose hepatitis B immunoglobulin on post-transplant hepatitis B virus recurrence.
Topics: Adenine; Administration, Oral; Adult; Aged; Antiviral Agents; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Guanine; Hepatitis B, Chronic; Humans; Immunoglobulins; Immunologic Factors; Kaplan-Meier Estimate; Lamivudine; Liver Transplantation; Male; Middle Aged; Organophosphonates; Postoperative Complications; Proportional Hazards Models; Recurrence; Retrospective Studies; Tenofovir; Treatment Outcome | 2016 |
Nucleos(t)ide analog(s) prophylaxis after hepatitis B immunoglobulin withdrawal against hepatitis B and D recurrence after liver transplantation.
Topics: Adenine; Adult; Antiviral Agents; Coinfection; DNA, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Hepatitis D, Chronic; Humans; Immunoglobulins; Lamivudine; Liver Cirrhosis; Liver Transplantation; Male; Middle Aged; Organophosphonates; Secondary Prevention; Tenofovir; Treatment Outcome; Withholding Treatment; Young Adult | 2016 |
[HBsAg clearance rate in patients with HBeAg-positive chronic hepatitis B: a comparative effect analysis based on the real world].
Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Organophosphonates; Retrospective Studies; Telbivudine; Thymidine; Treatment Outcome | 2016 |
Silver Ions in Non-canonical DNA Base Pairs: Metal-Mediated Mismatch Stabilization of 2'-Deoxyadenosine and 7-Deazapurine Derivatives with 2'-Deoxycytidine and 2'-Deoxyguanosine.
Topics: Adenine; Anions; Base Pair Mismatch; Base Pairing; Binding Sites; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; DNA; Guanine; Nucleic Acid Conformation; Nucleosides; Oligonucleotides; Purines; Silver; Solid-Phase Synthesis Techniques | 2016 |
Interactions of Nucleic Acid Bases with Temozolomide. Stacked, Perpendicular, and Coplanar Heterodimers.
Topics: Adenine; Cytosine; Dacarbazine; Dimerization; Guanine; Quantum Theory; Temozolomide; Thymine; Uracil | 2016 |
Management of Clevudine-Resistant Chronic Hepatitis B: A Multicenter Cohort Study.
Topics: Adenine; Adult; Aged; Antiviral Agents; Arabinofuranosyluracil; Cohort Studies; Disease Management; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Viral Load | 2017 |
Denys-Drash syndrome associated WT1 glutamine 369 mutants have altered sequence-preferences and altered responses to epigenetic modifications.
Topics: Adenine; Amino Acid Substitution; Crystallography, X-Ray; Cytosine; Denys-Drash Syndrome; DNA; Epigenesis, Genetic; Glutamine; Guanine; Humans; Mutation; WT1 Proteins | 2016 |
New Insights into the Reactivity of Cisplatin with Free and Restrained Nucleophiles: Microsolvation Effects and Base Selectivity in Cisplatin-DNA Interactions.
Topics: Adenine; Cisplatin; DNA; Guanine; Imidazoles; Quantum Theory; Water | 2016 |
Sequence-dependent separation of trinucleotides by ion-interaction reversed-phase liquid chromatography-A structure-retention study assisted by soft-modelling and molecular dynamics.
Topics: Adenine; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Guanine; Molecular Dynamics Simulation; Neural Networks, Computer; Oligonucleotides; Quantitative Structure-Activity Relationship; Solvents; Static Electricity; Thymine; Water | 2016 |
Comparison of the clinical outcomes between antiviral-naïve patients treated with entecavir and lamivudine-resistant patients receiving adefovir add-on lamivudine combination treatment.
Topics: Adenine; Adult; Alanine Transaminase; Antibodies, Viral; Antiviral Agents; Disease Progression; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Follow-Up Studies; Genotype; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Treatment Outcome | 2016 |
Induction of IFN-λ3 as an additional effect of nucleotide, not nucleoside, analogues: a new potential target for HBV infection.
Topics: Adenine; Adult; Aged; Aged, 80 and over; Antiviral Agents; Asymptomatic Infections; Carcinoma, Hepatocellular; Culture Media, Conditioned; DNA, Viral; Female; Gene Expression; Genotype; Guanine; Hep G2 Cells; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; HT29 Cells; Humans; Interferons; Interleukins; Lamivudine; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Organophosphonates; Polymorphism, Genetic; Recombinant Proteins; Tenofovir; Up-Regulation; Young Adult | 2018 |
Comparison of Detection Rate and Mutational Pattern of Drug-Resistant Mutations Between a Large Cohort of Genotype B and Genotype C Hepatitis B Virus-Infected Patients in North China.
Topics: Adenine; Adult; Antiviral Agents; China; Cohort Studies; Drug Resistance, Multiple, Viral; Female; Gene Expression; Genotype; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Microbial Sensitivity Tests; Middle Aged; Mutation Rate; Organophosphonates; Phylogeny; Viral Proteins | 2017 |
DNMT1 modulation in chronic hepatitis B patients and hypothetic influence on mitochondrial DNA methylation status during long-term nucleo(t)side analogs therapy.
Topics: Adenine; Aged; Antiviral Agents; Cross-Sectional Studies; Cytosine; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; DNA, Mitochondrial; Female; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Middle Aged; Nucleosides; Organophosphonates; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; Telbivudine; Thymidine | 2017 |
Ultrafast Electronic Deactivation Dynamics of Xanthosine Monophosphate.
Topics: Adenine; Electrons; Guanine; Kinetics; Light; Photochemical Processes; Protons; Ribonucleotides; Spectrometry, Fluorescence; Thermodynamics; Xanthine | 2017 |
Comparative evaluation of long-term monotherapies & combination therapies in patients with chronic hepatitis B: A pilot study.
Topics: Adenine; Adult; Drug Combinations; Drug Resistance, Viral; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Pilot Projects; Tenofovir | 2016 |
Direct Determination of Metal Complexes' Interaction with DNA by Atomic Telemetry and Multiscale Molecular Dynamics.
Topics: Adenine; Cisplatin; Coordination Complexes; DNA; Guanine; Hydrogen Bonding; Models, Molecular; Molecular Dynamics Simulation; Organoplatinum Compounds; Spectrometry, X-Ray Emission; Telemetry | 2017 |
Genetic Predisposition To Acquire a Polybasic Cleavage Site for Highly Pathogenic Avian Influenza Virus Hemagglutinin.
Topics: Adenine; Animals; Chickens; Genetic Predisposition to Disease; Guanine; Hemagglutinin Glycoproteins, Influenza Virus; High-Throughput Nucleotide Sequencing; Influenza A Virus, H5N1 Subtype; Influenza in Birds; RNA, Viral; Virulence | 2017 |
Evolutionary trends of resistance mutational patterns of HBV reverse transcriptase over years (2002-2012) of different treatment regimens: The legacy of lamivudine/adefovir combination treatment.
Topics: Adenine; Antiviral Agents; DNA Mutational Analysis; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Evolution, Molecular; Genotype; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Mutation; Organophosphonates; Polymorphism, Genetic; RNA-Directed DNA Polymerase; Sequence Analysis; Tenofovir; Treatment Failure | 2017 |
Effect of the reflectional symmetry on the coherent hole transport across DNA hairpins.
Topics: Adenine; DNA; Guanine; Quantum Theory | 2017 |
A comparative study on the experimental and calculated results of mid-infrared and Raman vibrational modes of nucleic acid bases.
Topics: Adenine; Crystallization; Cytosine; Guanine; Hydrogen Bonding; Molecular Conformation; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Thymine; Uracil | 2017 |
A different inhibitor is required for overcoming entecavir resistance: a comparison of four rescue therapies in a retrospective study.
Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Practice Guidelines as Topic; Retrospective Studies; Tenofovir; Treatment Outcome; Viral Load | 2017 |
Robust IR-based detection of stable and fractionally populated G-C
Topics: Adenine; Anti-Bacterial Agents; Base Pairing; Binding Sites; Chromosomal Instability; Circular Dichroism; DNA; Echinomycin; Feasibility Studies; Guanine; Hydrogen Bonding; Hydrogen-Ion Concentration; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Spectrophotometry; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared; Stereoisomerism | 2017 |
Mechanisms of the Formation of Adenine, Guanine, and Their Analogues in UV-Irradiated Mixed NH
Topics: Adenine; Ammonia; Guanine; Ice; Purines; Ultraviolet Rays; Water | 2017 |
Structure-Activity Relationships Reveal Key Features of 8-Oxoguanine: A Mismatch Detection by the MutY Glycosylase.
Topics: Adenine; Base Pair Mismatch; DNA Glycosylases; DNA Repair; Escherichia coli; Guanine; Models, Molecular; Substrate Specificity | 2017 |
Ultrafast structural dynamics of photoexcited adenine.
Topics: 2-Aminopurine; Adenine; Guanine; Quantum Theory; Spectrum Analysis, Raman; Ultraviolet Rays | 2017 |
Lactate serum concentrations during treatment with nucleos(t)ide analogues in hepatitis B with or without cirrhosis.
Topics: Acidosis, Lactic; Adenine; Adult; Aged; Aged, 80 and over; Antiviral Agents; Biomarkers; Drug Therapy, Combination; Female; Guanine; Hepatitis B, Chronic; Humans; Lactic Acid; Lamivudine; Liver Cirrhosis; Male; Middle Aged; Organophosphonates; Prospective Studies; Risk Factors; Sex Factors; Tenofovir; Time Factors; Treatment Outcome; Up-Regulation; Young Adult | 2017 |
New nucleoside hydrolase with transribosylation activity from Agromyces sp. MM-1 and its application for enzymatic synthesis of 2'-O-methylribonucleosides.
Topics: Actinomycetales; Adenine; Adenosine; Biocatalysis; Guanine; Hydrolysis; N-Glycosyl Hydrolases; Uridine | 2018 |
Reverse Transcription Past Products of Guanine Oxidation in RNA Leads to Insertion of A and C opposite 8-Oxo-7,8-dihydroguanine and A and G opposite 5-Guanidinohydantoin and Spiroiminodihydantoin Diastereomers.
Topics: Adenine; Guanidines; Guanine; Guanosine; Hydantoins; Kinetics; Oxidation-Reduction; Reverse Transcription; RNA; RNA-Directed DNA Polymerase; Spiro Compounds; Stereoisomerism | 2017 |
Poly-l-cysteine/electrospun copper oxide nanofibers-zinc oxide nanoparticles nanocomposite as sensing element of an electrochemical sensor for simultaneous determination of adenine and guanine in biological samples and evaluation of damage to dsDNA and DN
Topics: Adenine; Biosensing Techniques; Copper; Cysteine; DNA; DNA Damage; Electrochemical Techniques; Guanine; Humans; Metal Nanoparticles; Nanocomposites; Nanofibers; Purines; Spectroscopy, Fourier Transform Infrared; Ultraviolet Rays; Zinc Oxide | 2017 |
Androgen receptor cytosine, adenine, and guanine trinucleotide repeat polymorphism in Korean patients with endometriosis: A case-control study.
Topics: Adenine; Alleles; Case-Control Studies; Chi-Square Distribution; Cytosine; Endometriosis; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Guanine; Humans; Polymerase Chain Reaction; Polymorphism, Genetic; Prospective Studies; Receptors, Androgen; Republic of Korea; Trinucleotide Repeats | 2017 |
Copper-Nitrogen-Doped Graphene Hybrid as an Electrochemical Sensing Platform for Distinguishing DNA Bases.
Topics: Adenine; Catalysis; Coordination Complexes; Copper; Cytosine; DNA; Electrochemical Techniques; Electrodes; Graphite; Guanine; Nitrogen; Oxidation-Reduction; Reproducibility of Results; Thymine | 2017 |
Role of photoresponse of π electrons in light-driven DNA dissociations.
Topics: Adenine; Base Pairing; Computer Simulation; Cytosine; DNA; Electrons; Guanine; Hydrogen Bonding; Light; Models, Genetic; Models, Molecular; Photochemical Processes; Thymine | 2017 |
Solid-State Nanopore Analysis of Diverse DNA Base Modifications Using a Modular Enzymatic Labeling Process.
Topics: Adenine; Base Pair Mismatch; Biosensing Techniques; DNA; DNA Damage; DNA Repair; Epigenesis, Genetic; Guanine; Humans; Models, Molecular; Nanopores; Nanotechnology; Neoplasms; Uracil | 2017 |
Intermolecular magnetic interactions in stacked DNA base pairs.
Topics: Adenine; Base Pairing; Cytosine; DNA; Guanine; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Physical Phenomena; Thymine | 2017 |
Thioflavin T binds dimeric parallel-stranded GA-containing non-G-quadruplex DNAs: a general approach to lighting up double-stranded scaffolds.
Topics: Adenine; Benzothiazoles; Biosensing Techniques; Dimerization; DNA; Fluorescent Dyes; G-Quadruplexes; Guanine; Hydrogen-Ion Concentration; Metals; Thiazoles | 2017 |
Comparing Efficacy of Lamivudine, Adefovir Dipivoxil, Telbivudine, and Entecavir in Treating Nucleoside Analogues Naïve for HBeAg-Negative Hepatitis B with Medium Hepatitis B Virus (HBV) DNA Levels.
Topics: Adenine; Adult; Alanine Transaminase; DNA, Viral; Female; Follow-Up Studies; Guanine; Hepatitis B; Hepatitis B e Antigens; Humans; Lamivudine; Male; Multivariate Analysis; Nucleosides; Organophosphonates; Proportional Hazards Models; Telbivudine; Thymidine | 2017 |
A novel electrochemical sensor based on Cu@Ni/MWCNTs nanocomposite for simultaneous determination of guanine and adenine.
Topics: Adenine; Biosensing Techniques; Copper; Electrochemical Techniques; Guanine; Nanoparticles; Nanotubes, Carbon; Nickel | 2018 |
Persistence of SIV in the brain of SIV-infected Chinese rhesus macaques with or without antiretroviral therapy.
Topics: Adenine; Amino Acid Sequence; Animals; Antiretroviral Therapy, Highly Active; Basal Ganglia; Brain Stem; DNA, Viral; Female; Gray Matter; Guanine; HIV Envelope Protein gp120; Macaca mulatta; Male; Microglia; Mutation; Phylogeny; Sequence Alignment; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Spinal Cord; White Matter | 2018 |
Mixed guanine, adenine base quartets: possible roles of protons and metal ions in their stabilization.
Topics: Adenine; Base Pairing; Base Sequence; Cations; G-Quadruplexes; Guanine; Hydrogen Bonding; Metals, Alkali; Models, Chemical; Protons; Quantum Theory | 2018 |
Solvent effect on the intermolecular proton transfer of the Watson and Crick guanine-cytosine and adenine-thymine base pairs: a polarizable continuum model study.
Topics: Adenine; Base Pairing; Cytosine; DNA; Guanine; Models, Molecular; Protons; Solvents; Thymine | 2018 |
Reactivity of prehydrated electrons toward nucleobases and nucleotides in aqueous solution.
Topics: Adenine; Anions; Cytosine; DNA Damage; Electrons; Guanine; Guanine Nucleotides; Nucleotides; Radiation, Ionizing; Solutions; Spectrophotometry, Ultraviolet; Thymine; Water | 2017 |
Direct Detection of Drug-Resistant Hepatitis B Virus in Serum Using a Dendron-Modified Microarray.
Topics: Adenine; Dendrimers; DNA, Viral; Drug Resistance, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Microarray Analysis; Mutation; Nucleic Acid Amplification Techniques; Organophosphonates; Reverse Transcriptase Polymerase Chain Reaction | 2018 |
Nucleic Bases Alkylation with Acrylonitrile and Cyanoethylene Oxide: A Computational Study.
Topics: Acrylonitrile; Adenine; Alkylation; Cytosine; Density Functional Theory; Ethylene Oxide; Guanine; Kinetics; Nucleic Acid Conformation; Thymine | 2018 |
Selected health and lifestyle factors, cytosine-adenine-guanine status, and phenoconversion in Huntington's disease.
Topics: Adenine; Adult; Cytosine; Environment; Female; Follow-Up Studies; Guanine; Humans; Huntingtin Protein; Huntington Disease; Life Style; Male; Middle Aged; Motor Activity; Proportional Hazards Models; Trinucleotide Repeat Expansion | 2018 |
The solute transport profile of two Aza-guanine transporters from the Honey bee pathogen Paenibacillus larvae.
Topics: Adenine; Amino Acid Sequence; Animals; Aspergillus nidulans; Bacterial Proteins; Bees; Biological Transport; Guanine; Membrane Transport Proteins; Paenibacillus larvae; Sequence Alignment; Substrate Specificity; Uracil; Xanthine | 2018 |
Thermally induced hopping model for long-range triplet excitation energy transfer in DNA.
Topics: Adenine; Base Pairing; Base Sequence; DNA; DNA Damage; Energy Transfer; Guanine; Hot Temperature; Models, Chemical; Nucleic Acid Conformation; Thymine | 2018 |
Molecular investigation of evaporation of biodroplets containing single-strand DNA on graphene surface.
Topics: Adenine; Base Sequence; Cytosine; DNA, Single-Stranded; Graphite; Guanine; Hydrogen Bonding; Molecular Dynamics Simulation; Nucleic Acid Conformation; Surface Properties; Thymine | 2018 |
Detecting RNA base methylations in single cells by in situ hybridization.
Topics: Adenine; Escherichia coli; Escherichia coli Proteins; Guanine; In Situ Hybridization, Fluorescence; Methylation; Methyltransferases; Microscopy, Fluorescence; RNA; RNA, Ribosomal; Single-Cell Analysis; Uridine | 2018 |
Purine-Derived Nitroxides for Noncovalent Spin-Labeling of Abasic Sites in Duplex Nucleic Acids.
Topics: 2-Aminopurine; Adenine; Cyclic N-Oxides; Cytosine; DNA; Guanine; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acids; Purines; RNA; Spin Labels; Thymine | 2018 |
Surface enhanced Raman spectroscopy of Chlamydia trachomatis and Neisseria gonorrhoeae for diagnostics, and extra-cellular metabolomics and biochemical monitoring.
Topics: Adenine; Cell Line; Chlamydia Infections; Chlamydia trachomatis; Gold; Gonorrhea; Guanine; Humans; Metabolome; Metabolomics; Metal Nanoparticles; Neisseria gonorrhoeae; Sexually Transmitted Diseases; Silver; Spectrum Analysis, Raman; Vibration | 2018 |
Gauging the Nanotoxicity of h2D-C
Topics: Adenine; Cytosine; DNA, Single-Stranded; Guanine; Thymine | 2018 |
Electronic Resonances of Nucleobases Using Stabilization Methods.
Topics: Adenine; Cytosine; Electrochemical Techniques; Genomic Instability; Guanine; Quantum Theory; Thymine | 2018 |
Multiporous molybdenum carbide nanosphere as a new charming electrode material for highly sensitive simultaneous detection of guanine and adenine.
Topics: Adenine; Biosensing Techniques; Electrochemical Techniques; Electrodes; Guanine; Humans; Limit of Detection; Molybdenum; Nanospheres; Porosity | 2018 |
Hepatitis B virus rtA181T/sW172non-stop mutation may increase resistance fold to adefovir- and entecavir-resistant mutants compared to rtA181T/sW172* mutation.
Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Female; Genotype; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Mutation; Organophosphonates; RNA-Directed DNA Polymerase | 2018 |
Trends in hepatitis B virus resistance to nucleoside/nucleotide analogues in North China from 2009-2016: A retrospective study.
Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; Child; Child, Preschool; China; DNA, Viral; Drug Resistance, Viral; Female; Genotype; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Retrospective Studies; Telbivudine; Thymidine; Virus Activation; Virus Replication | 2018 |
Graphene oxide reinforced core-shell structured Ag@Cu
Topics: Adenine; Biosensing Techniques; Catalysis; Copper; Dopamine; Gold; Graphite; Guanine; Nanostructures; Oxidation-Reduction; Uric Acid | 2018 |
To use entecavir, tenofovir disoproxil fumarate or tenofovir alafenamide: it's all about choosing the right patient!
Topics: Adenine; Alanine; Anti-HIV Agents; Guanine; HIV Infections; Humans; Tenofovir | 2018 |
Combination therapy for chronic hepatitis B: The future and beyond.
Topics: Adenine; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interferon-alpha; Organophosphonates; Polyethylene Glycols; Recombinant Proteins | 2018 |
Why Do Silver Trimers Intercalated in DNA Exhibit Unique Nonlinear Properties That Are Promising for Applications?
Topics: Adenine; Cytosine; DNA; Guanine; Intercalating Agents; Models, Molecular; Nucleic Acid Conformation; Quantum Theory; Silver | 2018 |
48-Week Outcome after Cessation of Nucleos(t)ide Analogue Treatment in Chronic Hepatitis B Patient and the Associated Factors with Relapse.
Topics: Adenine; Adult; Antiviral Agents; Female; Follow-Up Studies; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Nucleosides; Organophosphonates; Outpatients; Prognosis; Prospective Studies; Recurrence; Risk Factors; RNA, Viral; Telbivudine; Time Factors; Treatment Outcome; Withholding Treatment | 2018 |
Long-term results of chronic hepatitis B antiviral treatment with nucleos(t)ide analogues: a single center experience.
Topics: Adenine; Adult; Aged; Aged, 80 and over; Antiviral Agents; Drug Therapy, Combination; Female; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Retrospective Studies; Telbivudine; Tenofovir; Young Adult | 2019 |
Tracking Photoinduced Charge Separation in DNA: from Start to Finish.
Topics: Adenine; DNA; Fluorescent Dyes; Free Radicals; Guanine; Inverted Repeat Sequences; Photochemistry; Static Electricity; Ultraviolet Rays | 2018 |
Single-Stranded DNA Oligonucleotides Retain Rise Coordinates Characteristic of Double Helices.
Topics: Adenine; Density Functional Theory; DNA, B-Form; DNA, Single-Stranded; Guanine; Models, Chemical; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Thermodynamics | 2018 |
Protonation of Nucleobases in Single- and Double-Stranded DNA.
Topics: 5-Methylcytosine; Adenine; Base Sequence; DNA, Single-Stranded; Guanine; Hydrogen-Ion Concentration; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Osmolar Concentration; Protons; Thymine | 2018 |
In vitro lesion bypass by human PrimPol.
Topics: Adenine; DNA Damage; DNA Primase; DNA-Directed DNA Polymerase; Guanine; Humans; Magnesium; Multifunctional Enzymes; Uracil | 2018 |
Poly(glycine)/graphene oxide modified glassy carbon electrode: Preparation, characterization and simultaneous electrochemical determination of dopamine, uric acid, guanine and adenine.
Topics: Adenine; Carbon; Catalysis; Dopamine; Electrochemical Techniques; Electrodes; Graphite; Guanine; Limit of Detection; Microscopy, Electron, Scanning; Oxidation-Reduction; Oxides; Peptides; Reproducibility of Results; Spectroscopy, Fourier Transform Infrared; Uric Acid | 2018 |
[A Case of Fanconi's Syndrome Induced by Adefovir in Hepatitis Type B Patient].
Topics: Adenine; Aged; Antiviral Agents; Fanconi Syndrome; Female; Guanine; Hepatitis B, Chronic; Humans; Organophosphonates | 2016 |
A novel mass spectrometry method based on competitive non-covalent interaction for the detection of biomarkers.
Topics: Adenine; Aptamers, Nucleotide; Biomarkers; Biosensing Techniques; Cytosine; DNA, Single-Stranded; Gold; Guanine; Humans; Limit of Detection; Male; Metal Nanoparticles; Prostate-Specific Antigen; Reproducibility of Results; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thymine | 2018 |
Adenine-Driven Structural Switch from a Two- to Three-Quartet DNA G-Quadruplex.
Topics: Adenine; Base Sequence; DNA; G-Quadruplexes; Guanine; Models, Molecular; Nucleic Acid Conformation; Proton Magnetic Resonance Spectroscopy | 2018 |
Synthesis, Optoelectronic Properties, Self-Association, and Base Pairing of Nucleobase-Functionalized Oligothiophenes.
Topics: Adenine; Base Pairing; Chloroform; Cytosine; Dimerization; Dimethylformamide; Electrochemical Techniques; Guanine; Hydrogen Bonding; Molecular Structure; Semiconductors; Solvents; Thermodynamics; Thiophenes; Uracil | 2018 |
Repeat length variations in ATXN1 and AR modify disease expression in Alzheimer's disease.
Topics: Adenine; Adult; Aged; Aged, 80 and over; Alzheimer Disease; Ataxin-1; Cytosine; Female; Genetic Variation; Genome-Wide Association Study; Guanine; Humans; Male; Middle Aged; Polymorphism, Genetic; Receptors, Androgen; Repetitive Sequences, Nucleic Acid; Temporal Lobe | 2019 |
Single step grown MoS
Topics: Adenine; Biosensing Techniques; DNA; Electrochemical Techniques; Electrodes; Graphite; Guanine; Limit of Detection | 2019 |
Management of individuals with chronic hepatitis B virus infection and persistent normal or mildly elevated aminotransferase levels.
Topics: Adenine; Adult; Alanine Transaminase; Antiviral Agents; Biopsy; Disease Management; DNA, Viral; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Liver Cirrhosis; Male; Organophosphonates; Retrospective Studies | 2019 |
Very late onset post-transplant diffuse large B cell lymphoma in a liver transplant recipient with hepatitis B: A case report.
Topics: Adenine; Antiviral Agents; Biopsy, Fine-Needle; Chemoradiotherapy; Guanine; Hepatitis B; Hepatitis B virus; Humans; Immunosuppressive Agents; Liver Transplantation; Lymphoma, Large B-Cell, Diffuse; Male; Middle Aged; Organophosphonates; Tomography, X-Ray Computed; Treatment Outcome; Virus Replication | 2018 |
UV Absorption and Magnetic Circular Dichroism Spectra of Purine, Adenine, and Guanine: A Coupled Cluster Study in Vacuo and in Aqueous Solution.
Topics: Adenine; Circular Dichroism; Guanine; Models, Chemical; Models, Molecular; Purines; Quantum Theory; Spectrophotometry, Ultraviolet; Thermodynamics; Water | 2019 |
Performance of serum HBcrAg in chronic hepatitis B patients with 8-year nucleos(t)ide analogs therapy.
Topics: Adenine; Adult; Antiviral Agents; Female; Guanine; Hepatitis B Core Antigens; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Male; Organophosphonates; Retrospective Studies; Seroconversion | 2019 |
The polyanions heparin and suramin impede binding of free adenine to a DNA glycosylase from C. pseudotuberculosis.
Topics: Adenine; Catalytic Domain; Corynebacterium pseudotuberculosis; DNA; DNA Glycosylases; DNA Repair; Guanine; Heparin; Kinetics; Mutagenesis; Mutation; N-Glycosyl Hydrolases; Polyelectrolytes; Polymers; Suramin | 2019 |
Artificial Sandwich Base for Monitoring Single-Nucleobase Changes and Charge-Transfer Rates in DNA.
Topics: Adenine; Cytosine; DNA; Electrochemical Techniques; Guanine; Thymine | 2019 |
Structure of a (3+1) hybrid G-quadruplex in the PARP1 promoter.
Topics: Adenine; DNA; DNA Repair; G-Quadruplexes; Guanine; Humans; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Poly (ADP-Ribose) Polymerase-1; Promoter Regions, Genetic | 2019 |
Methylation status of the stimulator of interferon genes promoter in patients with chronic hepatitis B.
Topics: Adenine; Adult; Antiviral Agents; Biomarkers; DNA, Viral; Female; Guanine; Hepatitis B, Chronic; Humans; Leukocytes, Mononuclear; Male; Methylation; Middle Aged; Organophosphonates; Polymerase Chain Reaction; Promoter Regions, Genetic; RNA, Messenger; Sustained Virologic Response | 2018 |
Ionization and Electron Attachment for Nucleobases in Water.
Topics: Adenine; Cytosine; Electrons; Guanine; Molecular Dynamics Simulation; Oxidation-Reduction; Quantum Theory; Thymine; Uracil; Water | 2019 |
Anticancer drug impact on DNA - a study by neutron spectroscopy coupled with synchrotron-based FTIR and EXAFS.
Topics: Adenine; Antineoplastic Agents; Cell Line, Tumor; DNA; Glutathione; Guanine; Humans; Neutrons; Nucleic Acid Conformation; Palladium; Platinum Compounds; Spectroscopy, Fourier Transform Infrared; Synchrotrons; X-Ray Absorption Spectroscopy | 2019 |
Purine Functional Group Type and Placement Modulate the Interaction with Carbon-Fiber Microelectrodes.
Topics: Adenine; Adsorption; Brain; Carbon Fiber; Diffusion; Electrochemistry; Guanine; Microelectrodes; Oxidation-Reduction; Purines | 2019 |
Single molecule glycosylase studies with engineered 8-oxoguanine DNA damage sites show functional defects of a MUTYH polyposis variant.
Topics: Adenine; Adenomatous Polyposis Coli; Animals; Colorectal Neoplasms; DNA Damage; DNA Glycosylases; Escherichia coli; Genomic Instability; Guanine; Humans; Mice; Mutation; Oxidative Stress | 2019 |
Photoinduced electron transfer in 5-bromouracil labeled DNA. A contrathermodynamic mechanism revisited by electron transfer theories.
Topics: Adenine; Bromouracil; DNA; Electron Transport; Electrons; Guanine; Kinetics; Light; Models, Molecular; Nucleic Acid Conformation; Photochemical Processes; Structure-Activity Relationship; Thermodynamics | 2019 |
Reduced levels of modified nucleosides in the urine of autistic children. Preliminary studies.
Topics: Adenine; Adenosine; Adolescent; Autistic Disorder; Child; Child, Preschool; Chromatography, Liquid; Female; Guanine; Guanosine; Humans; Male; Mass Spectrometry | 2019 |
Genotoxic and Epigenotoxic Alterations in the Lung and Liver of Mice Induced by Acrylamide: A 28 Day Drinking Water Study.
Topics: Acrylamide; Adenine; Administration, Oral; Animals; Carcinogens; DNA Adducts; Epigenesis, Genetic; Female; Guanine; Histones; Liver; Lung; Methylation; Mice; Mutagens; Water Pollutants, Chemical | 2019 |
Effective syntheses of 2',4'-BNA
Topics: 5-Methylcytosine; Adenine; Bridged-Ring Compounds; Glycosylation; Guanine; Nucleotides; Oligonucleotides; Thymine; Transition Temperature; Ultraviolet Rays | 2019 |
Melting of nucleobases. Getting the cutting edge of "Walden's Rule".
Topics: Adenine; Cytosine; Guanine; Hot Temperature; Models, Molecular; Molecular Structure; Nucleic Acid Conformation; Phase Transition; Surface Properties; Thermodynamics; Thymine; Uracil | 2019 |
Entecavir and Low Genetic Barrier Antiviral Agents for Hepatocellular Carcinoma in Hepatitis B Viral Cirrhosis: Propensity Score Matching.
Topics: Adenine; Adult; Aged; Antiviral Agents; Carcinoma, Hepatocellular; China; Female; Guanine; Hepatitis B; Hepatitis B virus; Humans; Incidence; Lamivudine; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Organophosphonates; Retrospective Studies; Risk Factors; Telbivudine | 2019 |
A simple and low-cost screen printed electrode for hepatocellular carcinoma methylation detection.
Topics: Adenine; Adsorption; Carbon; Carcinoma, Hepatocellular; Cell Line, Tumor; DNA; DNA Methylation; Electrochemical Techniques; Electrodes; Genes, p16; Gold; Guanine; Humans; Limit of Detection; Liver Neoplasms; Metal Nanoparticles; Promoter Regions, Genetic | 2019 |
Base-Pairing Properties of Double-Headed Nucleotides.
Topics: 2-Aminopurine; Adenine; Base Pair Mismatch; Base Pairing; Cytosine; DNA; Guanine; Hypoxanthine; Models, Molecular; Nucleic Acid Conformation; Nucleotides; Thymine | 2019 |
Effects of Noncanonical Base Pairing on RNA Folding: Structural Context and Spatial Arrangements of G·A Pairs.
Topics: Adenine; Base Pairing; Escherichia coli; Guanine; Hydrogen Bonding; Leishmania donovani; Models, Molecular; Nucleic Acid Conformation; RNA; RNA Folding; Saccharomyces cerevisiae; Software; Thermus thermophilus | 2019 |
Long-term Nucleotide Analogue Treatment Has Higher Levels of Renal Toxicities than Does Entecavir in Patients with Chronic Hepatitis B.
Topics: Adenine; Adult; Aged; Antiviral Agents; Chemical and Drug Induced Liver Injury; Female; Glomerular Filtration Rate; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Incidence; Male; Middle Aged; Nucleotides; Organophosphonates; Proportional Hazards Models; Retrospective Studies; Tenofovir; Time Factors; Treatment Outcome | 2020 |
Long-term prognosis of liver disease in patients with chronic hepatitis B virus infection receiving nucleos(t)ide analogue therapy: an analysis using a Markov chain model.
Topics: Adenine; Adult; Aged; Antiviral Agents; Carcinoma, Hepatocellular; Female; Guanine; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Liver Cirrhosis; Liver Neoplasms; Male; Markov Chains; Middle Aged; Nucleosides; Organophosphonates; Prognosis | 2019 |
Hydrogen-Atom Addition to Nucleobases in the Solid State: Characterization of the Corresponding Muoniated Radicals Using μSR.
Topics: Adenine; Cytosine; Free Radicals; Guanine; Hydrogen; Mesons; Molecular Structure; Spectrum Analysis; Thermodynamics; Thymine | 2019 |
[Hachimoji DNA extends coding possibilities].
Topics: Adenine; Cytosine; DNA; Guanine; Hydrogen Bonding; Molecular Structure; Nucleotides; Oligonucleotides; Synthetic Biology; Thymine | 2019 |
Interaction studies of sodium cyclamate with DNA revealed by spectroscopy methods.
Topics: Adenine; Base Pairing; Binding Sites; Cyclamates; DNA; Electrochemical Techniques; Ethidium; Fluorescent Dyes; Guanine; Nucleic Acid Denaturation; Scattering, Radiation; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Sweetening Agents | 2019 |
A case of entecavir-induced Fanconi syndrome.
Topics: Acidosis; Acute Kidney Injury; Adenine; Aged; Alanine; Antiviral Agents; Fanconi Syndrome; Guanine; Hepatitis B, Chronic; Humans; Hypokalemia; Hypophosphatemia; Male; Nucleosides; Tenofovir; Treatment Outcome; Withholding Treatment | 2019 |
Using Rosetta for RNA homology modeling.
Topics: Adenine; Aptamers, Nucleotide; Guanine; Models, Molecular; Nucleic Acid Conformation; Riboswitch; RNA | 2019 |
DFT and MD Studies of Formaldehyde-Derived DNA Adducts: Molecular-Level Insights into the Differential Mispairing Potentials of the Adenine, Cytosine, and Guanine Lesions.
Topics: Adenine; Base Pairing; Cytosine; Density Functional Theory; DNA Adducts; Formaldehyde; Guanine; Hydrogen Bonding; Models, Chemical; Molecular Dynamics Simulation; Nucleic Acid Conformation | 2019 |
From general base to general acid catalysis in a sodium-specific DNAzyme by a guanine-to-adenine mutation.
Topics: Adenine; Algorithms; Base Sequence; Binding Sites; Biocatalysis; DNA, Catalytic; Guanine; Kinetics; Mutation; Nucleic Acid Conformation; Nucleotide Motifs; RNA; Sodium; Substrate Specificity | 2019 |
Colloidal gold clusters formation and chemometrics for direct SERS determination of bioanalytes in complex media.
Topics: Adenine; Gold Colloid; Guanine; Humans; Least-Squares Analysis; Metal Nanoparticles; Models, Chemical; Multivariate Analysis; Spectrum Analysis, Raman | 2020 |
Modification of electron structure on the semiconducting single-walled carbon nanotubes for effectively electrosensing guanine and adenine.
Topics: Adenine; Dielectric Spectroscopy; Electrochemical Techniques; Electrodes; Guanine; Hydrogen-Ion Concentration; Limit of Detection; Nanotubes, Carbon; Pyrenes | 2019 |
Charge Transfer Platform and Catalytic Amplification of Phenanthroimidazole Derivative: A New Strategy for DNA Bases Recognition.
Topics: Adenine; Biosensing Techniques; Catalysis; Cytosine; Electrochemical Techniques; Guanine; Phenanthrolines; Thymine | 2019 |
Effect of the Electric Field on DNA Bases as Pigments for Nanodevices: A First-Principles Study.
Topics: Adenine; Cytosine; DNA; Guanine; Humans; Thymine | 2020 |
Development and validation of a rapid LC-MS/MS method for determination of methylated nucleosides and nucleobases in urine.
Topics: Adenine; Adult; Animals; Child; Chromatography, Liquid; Guanine; Humans; Linear Models; Nucleosides; Rats; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry | 2019 |
Repeat variations in polyglutamine disease-associated genes and cognitive function in old age.
Topics: Adenine; Cognition; Cytosine; Guanine; Humans; Peptides; Polymorphism, Genetic; Tandem Repeat Sequences | 2019 |
Immunomodulatory Mechanism of Acyclic Nucleoside Phosphates in Treatment of Hepatitis B Virus Infection.
Topics: Adenine; Adult; Aged; Antiviral Agents; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Immunomodulation; Interferon-alpha; Interleukin-10; Interleukin-12; Lamivudine; Leukocytes, Mononuclear; Lipopolysaccharides; Male; Nucleosides; Organophosphonates; Proto-Oncogene Proteins c-akt; Tenofovir | 2020 |
Identification of a novel heterozygous guanosine monophosphate reductase (GMPR) variant in a patient with a late-onset disorder of mitochondrial DNA maintenance.
Topics: Adenine; Aged; Cells, Cultured; Cytochrome-c Oxidase Deficiency; DNA Replication; DNA, Mitochondrial; Exome Sequencing; Female; Fibroblasts; GMP Reductase; Guanine; HEK293 Cells; HeLa Cells; Heterozygote; Humans; Late Onset Disorders; Muscle, Skeletal; Ophthalmoplegia; Oxidative Phosphorylation; RNA Splicing; Sequence Deletion | 2020 |
Novel strategy of electrochemical analysis of DNA bases with enhanced performance based on copper-nickel nanosphere decorated N,B-doped reduced graphene oxide.
Topics: Adenine; Animals; Biosensing Techniques; Catalysis; Cattle; Copper; DNA; Electrochemical Techniques; Glucose; Graphite; Guanine; Limit of Detection; Nanospheres; Nickel; Oxidation-Reduction | 2020 |
A deep learning framework to predict binding preference of RNA constituents on protein surface.
Topics: Adenine; Animals; Area Under Curve; Argonaute Proteins; Cytosine; Deep Learning; Gene Knockdown Techniques; Guanine; Humans; Mice; Phosphates; Protein Binding; Ribonuclease III; Ribose; RNA; RNA-Binding Proteins; RNA, Small Interfering; ROC Curve; Uracil | 2019 |
SERS discrimination of single DNA bases in single oligonucleotides by electro-plasmonic trapping.
Topics: Adenine; Cytosine; DNA; Gold; Guanine; Metal Nanoparticles; Nanopores; Optical Tweezers; Optics and Photonics; Single Molecule Imaging; Spectrum Analysis, Raman; Thymine | 2019 |
Simulated NIR spectra as sensitive markers of the structure and interactions in nucleobases.
Topics: Adenine; Binding Sites; Biophysical Phenomena; Computer Simulation; Crystallization; Cytosine; Guanine; Models, Molecular; Nucleic Acid Conformation; Powders; Sensitivity and Specificity; Spectroscopy, Near-Infrared; Thymine; Vibration | 2019 |
Significance of switching of the nucleos(t)ide analog used to treat Japanese patients with chronic hepatitis B virus infection from entecavir to tenofovir alafenamide fumarate.
Topics: Adenine; Aged; Alanine; Antibodies, Viral; Antiviral Agents; Female; Fumarates; Genotype; Guanine; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Japan; Male; Medication Adherence; Middle Aged; Multivariate Analysis; Surveys and Questionnaires; Tenofovir; Transaminases; Treatment Outcome | 2020 |
Fluorescence of the tri-cyclic adenine and isoguanine derivatives and their ribosides: possible analytical applications.
Topics: Adenine; Fluorescence; Glycosides; Guanine; Humans; Kinetics; Purine-Nucleoside Phosphorylase; Purines | 2019 |
Sublimation thermodynamics of nucleobases derived from fast scanning calorimetry.
Topics: Adenine; Calorimetry; Cytosine; Guanine; Pressure; Thermodynamics; Thymine; Uracil; Volatilization | 2020 |
Off-target effects of cytidine base editor and adenine base editor: What can we do?
Topics: Adenine; CRISPR-Cas Systems; Cytidine; Cytidine Deaminase; Gene Editing; Guanine; Humans | 2019 |
Effect of nucleos(t)ide analogue on serum HBsAg level in chronic hepatitis B patients: A 3-years study.
Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Female; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Nucleotidases; Organophosphonates; Viral Load | 2020 |
An IRMPD spectroscopic and computational study of protonated guanine-containing mismatched base pairs in the gas phase.
Topics: Adenine; Base Pair Mismatch; Crystallography, X-Ray; Gases; Guanine; Hydrogen Bonding; Models, Molecular; Photons; Spectrophotometry, Infrared; Thymine | 2020 |
Validation of hepatocellular carcinoma risk scores in Japanese chronic hepatitis B cohort receiving nucleot(s)ide analog.
Topics: Adenine; Adult; Alanine; Antiviral Agents; Asian People; Carcinoma, Hepatocellular; Cohort Studies; Female; Guanine; Hepatitis B, Chronic; Humans; Japan; Liver Neoplasms; Male; Middle Aged; Nucleotides; Platelet Count; Research Design; Risk; Tenofovir; Time Factors | 2020 |
A copper-based metal-organic framework/graphene nanocomposite for the sensitive and stable electrochemical detection of DNA bases.
Topics: Adenine; Animals; Biosensing Techniques; Copper; DNA; Electrochemical Techniques; Electrodes; Fishes; Graphite; Guanine; Male; Metal-Organic Frameworks; Nanocomposites; Spermatozoa | 2020 |
Pregnancy outcomes for pregnant women with chronic hepatitis B exposing to entecavir or adefovir dipivoxil therapy before or in early pregnancy.
Topics: Adenine; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Organophosphonates; Pregnancy; Pregnancy Outcome; Pregnant Women; Retrospective Studies; Treatment Outcome; Viral Load | 2022 |
Ligand Binding Mechanism and Its Relationship with Conformational Changes in Adenine Riboswitch.
Topics: Adenine; Bacterial Proteins; Guanine; Ligands; Models, Molecular; Molecular Dynamics Simulation; Mutation; Nucleic Acid Conformation; Purines; Pyrimidines; Riboswitch | 2020 |
Specificity profile of NAT/NCS2 purine transporters in Sinorhizobium (Ensifer) meliloti.
Topics: Adenine; Biological Transport, Active; Escherichia coli K12; Guanine; Hypoxanthine; Membrane Transport Proteins; Plant Root Nodulation; Rhizosphere; Root Nodules, Plant; Sinorhizobium meliloti; Symporters; Uric Acid; Xanthine | 2020 |
Graphene Oxide Nanoribbons in Chitosan for Simultaneous Electrochemical Detection of Guanine, Adenine, Thymine and Cytosine.
Topics: Adenine; Chitosan; Cytosine; Electrochemical Techniques; Graphite; Guanine; Nanotubes, Carbon; Thymine | 2020 |
Tenofovir alafenamide after switching from entecavir or nucleos(t)ide combination therapy for patients with chronic hepatitis B.
Topics: Adenine; Alanine; Antiviral Agents; Cohort Studies; Guanine; Hepatitis B, Chronic; Humans; Retrospective Studies; Tenofovir; Treatment Outcome | 2020 |
Base editors for simultaneous introduction of C-to-T and A-to-G mutations.
Topics: Adenine; Adenosine Deaminase; CRISPR-Associated Protein 9; CRISPR-Cas Systems; Cytosine; Deoxyribonuclease I; DNA; Gene Editing; Genome, Human; Glycoproteins; Guanine; HEK293 Cells; Humans; Mutation; Nuclear Proteins; RNA | 2020 |
Comparable Incidence of Hepatocellular Carcinoma in Chronic Hepatitis B Patients Treated with Entecavir or Tenofovir.
Topics: Adenine; Adult; Antiviral Agents; Carcinoma, Hepatocellular; Female; Guanine; Hepatitis B, Chronic; Humans; Incidence; Liver Neoplasms; Liver Transplantation; Male; Medication Adherence; Middle Aged; Phosphorous Acids; Retrospective Studies; Risk Assessment; Risk Factors; Sustained Virologic Response; Time Factors; Treatment Outcome | 2021 |
Hepatitis B virus mutation pattern rtA181S+T184I+M204I may contribute to multidrug resistance in clinical practice: Analysis of a large cohort of Chinese patients.
Topics: Adenine; Adult; Antiviral Agents; Asian People; Beijing; Cohort Studies; DNA, Viral; Drug Resistance, Multiple, Viral; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Longitudinal Studies; Male; Middle Aged; Mutation; Organophosphonates; Prevalence | 2020 |
First-principles characterization of the singlet excited state manifold in DNA/RNA nucleobases.
Topics: Adenine; Cytosine; Density Functional Theory; DNA; Guanine; RNA; Thymine; Uracil | 2020 |
Structure of a DNA polymerase abortive complex with the 8OG:dA base pair at the primer terminus.
Topics: Adenine; DNA Polymerase beta; DNA Primers; Guanine; Humans; Protein Conformation | 2020 |
Is tenofovir and entecavir combination therapy still the optimal treatment for chronic hepatitis B patients with prior suboptimal response?
Topics: Adenine; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Organophosphonates; Telbivudine; Tenofovir | 2020 |
Glycosylase base editors enable C-to-A and C-to-G base changes.
Topics: Adenine; Animals; APOBEC-1 Deaminase; Base Pairing; CRISPR-Associated Protein 9; CRISPR-Cas Systems; Cytidine Deaminase; Cytosine; Deoxyribonuclease I; DNA Glycosylases; DNA Repair; Escherichia coli; Gene Editing; Guanine; Rats; Uracil-DNA Glycosidase | 2021 |
Frequency and hydrogen bonding of nucleobase homopairs in small molecule crystals.
Topics: Adenine; Base Pairing; Crystallography, X-Ray; Cytosine; Databases, Protein; Guanine; Hydrogen Bonding; Hypoxanthine; Molecular Structure; Protein Conformation; Proteins; Small Molecule Libraries; Thymine; Uracil | 2020 |
Nucleic acid binding mechanism of flavone derivative, riviciclib: Structural analysis to unveil anticancer potential.
Topics: Adenine; Antineoplastic Agents; Benzopyrans; Binding Sites; Chromones; DNA; Flavones; Guanine; Metal Nanoparticles; Molecular Docking Simulation; Nucleic Acid Conformation; Phosphates; Piperidines; Pyrrolidines; RNA, Transfer; Silver; Spectrum Analysis, Raman; Sugars; Thymine | 2020 |
CAG Repeat Size Influences the Progression Rate of Spinocerebellar Ataxia Type 3.
Topics: Adenine; Adult; Ataxin-3; Cytosine; Disease Progression; Female; Guanine; Humans; Machado-Joseph Disease; Male; Middle Aged; Repressor Proteins; Spinocerebellar Ataxias | 2021 |
HCC risk reduction with oral nucleos(t)ide analogues in patients with chronic hepatitis B: Not perfect, not good enough.
Topics: Adenine; Administration, Oral; Alanine; Carcinoma, Hepatocellular; DNA, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Liver Neoplasms; Nucleotides; Tenofovir | 2020 |
Enzymatic synthesis of hypermodified DNA polymers for sequence-specific display of four different hydrophobic groups.
Topics: Adenine; Aptamers, Nucleotide; Base Pairing; Base Sequence; Cytosine; Deoxyribonucleosides; Dinucleoside Phosphates; DNA; DNA Replication; DNA-Directed DNA Polymerase; Guanine; Hydrophobic and Hydrophilic Interactions; Polymerase Chain Reaction; Polymers; Uracil | 2020 |
Insights into the Direct Oxidative Repair of Etheno Lesions: MD and QM/MM Study on the Substrate Scope of ALKBH2 and AlkB.
Topics: Adenine; AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; Catalytic Domain; Computational Biology; Cytosine; DNA Adducts; DNA Repair; Escherichia coli; Escherichia coli Proteins; Guanine; Humans; Mixed Function Oxygenases; Models, Molecular; Molecular Dynamics Simulation; Protein Conformation; Substrate Specificity | 2020 |
Scalable Synthesis, In Vitro cccDNA Reduction, and In Vivo Antihepatitis B Virus Activity of a Phosphonomethoxydeoxythreosyl Adenine Prodrug.
Topics: Adenine; Animals; Antiviral Agents; DNA, Circular; DNA, Viral; Drug Resistance, Viral; Guanine; Hepatitis B; Hepatitis B virus; Male; Mice; Mice, Inbred C57BL; Nucleosides; Prodrugs; Virus Replication | 2020 |
Unique Hydrogen Bonding of Adenine with the Oxidatively Damaged Base 8-Oxoguanine Enables Specific Recognition and Repair by DNA Glycosylase MutY.
Topics: Adenine; Base Pairing; Catalysis; Catalytic Domain; DNA; DNA Glycosylases; DNA Repair; Escherichia coli; Guanine; Hydrogen Bonding; Hydrolysis; Models, Molecular; Structure-Activity Relationship; Substrate Specificity | 2020 |
Nanogap-based all-electronic DNA sequencing devices using MoS
Topics: Adenine; Cytosine; Density Functional Theory; Disulfides; DNA; Electronics; Guanine; Models, Chemical; Molybdenum; Nanopores; Sequence Analysis, DNA; Thymine | 2020 |
Detection of nucleobases on borophene nanosheet: A DFT investigation.
Topics: Adenine; Adsorption; Boron; Cytosine; Density Functional Theory; Electron Transport; Guanine; Models, Molecular; Molecular Conformation; Thymine | 2021 |
Adsorption studies of nucleobases on ε-arsenene nanosheet based on first-principles research.
Topics: Adenine; Adsorption; Cytosine; Guanine; Thymine | 2021 |
Switching from entecavir to tenofovir alafenamide for chronic hepatitis B patients with low-level viraemia.
Topics: Adenine; Alanine; Antiviral Agents; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Prospective Studies; Tenofovir; Treatment Outcome; Viremia | 2021 |
Understanding structural and molecular properties of complexes of nucleobases and Au13 golden nanocluster by DFT calculations and DFT-MD simulation.
Topics: Adenine; Biosensing Techniques; Cytosine; Density Functional Theory; DNA; Gold; Guanine; Macromolecular Substances; Metal Nanoparticles; Models, Molecular; Molecular Dynamics Simulation; Nanostructures; Nucleic Acid Conformation; Quantum Theory; RNA; Thymine | 2021 |
Multiple drug-resistant HBV mutation may contribute to poor response of adefovir + entecavir in entecavir-resistant patients.
Topics: Adenine; Adult; Aged; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Mutation; Organophosphonates; RNA-Directed DNA Polymerase; Tenofovir; Viral Load; Virus Replication | 2021 |
Quantum Simulation of the Silicene and Germanene for Sensing and Sequencing of DNA/RNA Nucleobases.
Topics: Adenine; Adsorption; Biosensing Techniques; Computer Simulation; Cytosine; DNA; Germanium; Guanine; RNA; Silicon; Thymine; Uracil | 2021 |
Investigation of multidrug-resistance mutations of hepatitis B virus (HBV) in a large cohort of chronic HBV-infected patients with treatment of nucleoside/nucleotide analogs.
Topics: Adenine; Adult; Antiviral Agents; Cohort Studies; DNA, Viral; Drug Resistance, Multiple, Viral; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Longitudinal Studies; Male; Middle Aged; Mutation; Nucleosides; Nucleotides; Organophosphonates; Phylogeny; Telbivudine; Viral Load; Virus Replication | 2021 |
FOXO1 controls protein synthesis and transcript abundance of mutant polyglutamine proteins, preventing protein aggregation.
Topics: Adenine; Amyloidogenic Proteins; Autophagy; Cytosine; Forkhead Box Protein O1; Gene Expression Regulation; Guanine; HEK293 Cells; Humans; Mutant Proteins; Peptides; Protein Aggregation, Pathological; Protein Biosynthesis; Proteolysis; RNA-Binding Proteins; RNA, Messenger; Trinucleotide Repeats | 2021 |
Insights into the mismatch discrimination mechanism of Y-family DNA polymerase Dpo4.
Topics: Adenine; Amino Acid Sequence; Archaeal Proteins; Binding Sites; Cloning, Molecular; Crystallography, X-Ray; DNA Polymerase beta; Escherichia coli; Gene Expression; Genetic Vectors; Guanine; Kinetics; Models, Molecular; Nucleic Acid Conformation; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Sulfolobus solfataricus; Thermodynamics | 2021 |
Influence of the Number, Nature and Position of Methyl Posttranscriptional Modifications on Nucleobase Stacking in RNA.
Topics: Adenine; Cytosine; Density Functional Theory; Dimerization; Guanine; Methylation; RNA; RNA Processing, Post-Transcriptional; Uracil | 2021 |
Structure of the mammalian adenine DNA glycosylase MUTYH: insights into the base excision repair pathway and cancer.
Topics: Adenine; Adenomatous Polyposis Coli; Amino Acid Motifs; Animals; DNA; DNA Glycosylases; DNA Repair; DNA Replication; Guanine; Humans; Mice; Models, Molecular; Mutation; Proliferating Cell Nuclear Antigen; Zinc | 2021 |
Single molecule analysis indicates stimulation of MUTYH by UV-DDB through enzyme turnover.
Topics: Adenine; Animals; DNA Damage; DNA Glycosylases; DNA Repair; DNA Replication; Guanine; Hydrocarbons, Chlorinated; Mice; Oxidative Stress; Single Molecule Imaging | 2021 |
Simultaneous electrochemical detection of guanine and adenine using reduced graphene oxide decorated with AuPt nanoclusters.
Topics: Adenine; Alloys; Animals; Ascorbic Acid; Biosensing Techniques; DNA; Dopamine; Electrochemical Techniques; Electrodes; Gold; Graphite; Guanine; Limit of Detection; Male; Metal Nanoparticles; Nanocomposites; Oxidation-Reduction; Platinum; Salmon; Spermatozoa; Uric Acid | 2021 |
Synthesis of Oligonucleotides Containing Trans Mitomycin C DNA Adducts at N
Topics: Adenine; DNA Adducts; Guanine; Mitomycin; Oligonucleotides | 2021 |
Defects in 8-oxo-guanine repair pathway cause high frequency of C > A substitutions in neuroblastoma.
Topics: Adenine; Child; Cytosine; DNA Damage; DNA Glycosylases; DNA Repair; Female; Guanine; Guanosine; Humans; Male; Mutagenesis; Neoplasm Recurrence, Local; Neuroblastoma; Oxidative Stress; Polymorphism, Single Nucleotide | 2021 |
Kinetic Study of Transition Mutations from G-C to A-T Base Pairs in Watson-Crick DNA Base Pairs: Double Proton Transfers.
Topics: Adenine; Base Pairing; Cytosine; Density Functional Theory; Guanine; Kinetics; Protons; Thymine | 2021 |
Adenine shares the plane with G-quartet detected by surface-enhanced Raman spectroscopy.
Topics: Adenine; G-Quadruplexes; Guanine; Spectrum Analysis, Raman | 2021 |
Surface-enhanced Raman scattering of DNA bases using frozen silver nanoparticle dispersion as a platform.
Topics: Adenine; Beer; Cryoprotective Agents; Cytosine; Freezing; Glycerol; Guanine; Limit of Detection; Metal Nanoparticles; Silver; Spectrum Analysis, Raman; Sucrose; Thymidine | 2021 |
Nano-ZnS decorated hierarchically porous carbon electrocatalyst with multiple enzyme-like activities as a nanozyme sensing platform for simultaneous detection of dopamine, uric acid, guanine, and adenine.
Topics: Adenine; Ascorbic Acid; Carbon; Dopamine; Electrochemical Techniques; Guanine; Humans; Porosity; Uric Acid | 2021 |
Simultaneous determination of guanine and adenine in human saliva with graphite sparked screen-printed electrodes.
Topics: Adenine; Electrochemical Techniques; Electrodes; Graphite; Guanine; Humans; Saliva | 2022 |
Strategies and Perspectives for UV Resonance Raman Applicability in Clinical Analyses of Human Sperm RNA.
Topics: Adenine; Cell Line; Guanine; Humans; Infertility, Male; Male; Reproductive Techniques, Assisted; RNA; Semen Analysis; Spectrum Analysis, Raman; Spermatozoa; Ultraviolet Rays | 2021 |
Exploiting the optical sensing of fluorophore-tagged DNA nucleobases on hexagonal BN and Al-doped BN sheets: a computational study.
Topics: Adenine; Adsorption; Aluminum; Benzoxazoles; Boron Compounds; Cytosine; Density Functional Theory; Fluorescent Dyes; Guanine; Molecular Dynamics Simulation; Thymine | 2022 |
Effects of Long-Term Tenofovir and Entecavir Treatment on Bone Mineral Density in Patients with Chronic Hepatitis B.
Topics: Adenine; Antiviral Agents; Bone Density; Guanine; Hepatitis B, Chronic; Humans; Prospective Studies; Tenofovir; Treatment Outcome | 2022 |
Impact of switching to tenofovir alafenamide fumarate in patients with entecavir-treated chronic hepatitis B.
Topics: Adenine; Alanine; Antiviral Agents; Fumarates; Guanine; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Retrospective Studies; Tenofovir; Treatment Outcome | 2021 |
Scaled in Cartesian Coordinates Ab Initio Molecular Force Fields of DNA Bases: Application to Canonical Pairs.
Topics: Adenine; Base Pairing; Cytosine; DNA; Guanine; Models, Chemical; Spectrum Analysis; Thymine; Vibration | 2022 |
Ultrasound-aided synthesis of gold-loaded boron-doped graphene quantum dots interface towards simultaneous electrochemical determination of guanine and adenine biomolecules.
Topics: Adenine; Boron; Electrochemical Techniques; Electrodes; Gold; Graphite; Guanine; Metal Nanoparticles; Quantum Dots; Reproducibility of Results | 2022 |
The CAG-triplet in the androgen receptor gene and single-nucleotide polymorphisms in androgen pathway genes in patients with concomitant bladder and prostate cancer.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adenine; Androgens; Cytosine; Guanine; Humans; Male; Membrane Proteins; Polymorphism, Single Nucleotide; Prostatic Neoplasms; Receptors, Androgen; Urinary Bladder | 2022 |
A Comprehensive Triple-Repeat Primed PCR and a Long-Range PCR Agarose-Based Assay for Improved Genotyping of Guanine-Adenine-Adenine Repeats in Friedreich Ataxia.
Topics: Adenine; Friedreich Ataxia; Genotype; Guanine; Humans; Iron-Binding Proteins; Polymerase Chain Reaction; Sepharose; Trinucleotide Repeat Expansion; Trinucleotide Repeats | 2022 |
Premature transcription termination at the expanded GAA repeats and aberrant alternative polyadenylation contributes to the Frataxin transcriptional deficit in Friedreich's ataxia.
Topics: Adenine; Arsenicals; Frataxin; Friedreich Ataxia; Gallium; Guanine; Humans; Iron-Binding Proteins; Oligonucleotides, Antisense; Polyadenylation; RNA, Messenger; Transcription, Genetic; Trinucleotide Repeat Expansion | 2022 |
Association of promoter region A-1012G polymorphism (rs4516035) of vitamin-D receptor gene with coronary artery disease.
Topics: Adenine; Adult; Case-Control Studies; Coronary Artery Disease; Female; Genotype; Guanine; Humans; Male; Middle Aged; Pakistan; Promoter Regions, Genetic; Receptors, Calcitriol; Vitamin D; Vitamins | 2022 |
Skin fibroblast metabolomic profiling reveals that lipid dysfunction predicts the severity of Friedreich's ataxia.
Topics: 3-Hydroxybutyric Acid; Adenine; Carnitine; Ceramides; Coenzyme A; Fibroblasts; Friedreich Ataxia; Guanine; Humans; Iron; Phosphatidylglycerols; Sulfur; Triglycerides | 2022 |
Fluorescent adenine analogues with ESPT characteristic utilized for real-time detecting DNA adduct.
Topics: Adenine; Base Pairing; DNA Adducts; Guanine; Models, Molecular | 2022 |
Beyond the CAG triplet number: exploring potential predictors of delayed age of onset in Huntington's disease.
Topics: Adenine; Adult; Age of Onset; Child; Cytosine; Guanine; Humans; Huntington Disease; Neurodegenerative Diseases; Retrospective Studies; Trinucleotide Repeat Expansion | 2022 |
Similar risk of kidney function decline between tenofovir alafenamide and besifovir dipivoxil maleate in chronic hepatitis B.
Topics: Adenine; Alanine; Antiviral Agents; Guanine; Hepatitis B; Hepatitis B, Chronic; Humans; Kidney; Longitudinal Studies; Maleates; Organophosphonates; Renal Insufficiency, Chronic; Retrospective Studies; Tenofovir; Treatment Outcome | 2022 |
Resolution of Identity in Gas-Phase Dissociations of Mono- and Diprotonated DNA Trinucleotide Codons by
Topics: Adenine; Codon; Cytosine; DNA; Guanine; Phosphates; Protein Subunits; Protons; Thymine | 2022 |
Rationalizing the Unexpected Sensitivity in Excited State Lifetimes of Adenine to Tautomerization by Nonadiabatic Molecular Dynamics.
Topics: Adenine; Guanine; Molecular Dynamics Simulation; RNA | 2022 |
Characteristics Evaluation of a Barcode Sequence of Two
Topics: Adenine; Animals; Anura; Guanine; Indonesia; Nucleotides; Thymine | 2022 |
Identification of a novel missense mutation in non-syndromic familial multiple supernumerary teeth.
Topics: Adenine; Guanine; Humans; Mutation; Mutation, Missense; Polymorphism, Single Nucleotide; Protein Kinase C; Tooth, Supernumerary | 2022 |
Electrochemical determination of purine and pyrimidine bases using a 1,10-phenanthroline-Fe
Topics: Adenine; Animals; Biosensing Techniques; Carbon; Chitosan; Cytosine; DNA; Electrochemical Techniques; Graphite; Guanine; Male; Nanocomposites; Nanoparticles; Phenanthrolines; Purines; Pyrimidines; Semen; Thymine | 2022 |
Accelerating Hybrid Density Functional Theory Molecular Dynamics Simulations by Seminumerical Integration, Resolution-of-the-Identity Approximation, and Graphics Processing Units.
Topics: Adenine; Cytosine; Density Functional Theory; Guanine; Molecular Dynamics Simulation; Quantum Theory; Thymine | 2022 |
Affinities to Oxaliplatin: Vitamins from B Group vs. Nucleobases.
Topics: Adenine; Cisplatin; Cyclohexylamines; Cytosine; DNA; Guanine; Oxaliplatin; Platinum; Quantum Theory; Solvents; Thiamine; Vitamin A; Vitamins; Water | 2022 |
Nucleobase-Bonded Graphene Nanoribbon Junctions: Electron Transport from First Principles.
Topics: Adenine; Cytosine; DNA; Electron Transport; Graphite; Guanine; Hydrogen; Nanotubes, Carbon; Thymine | 2022 |
Direct Minisci-Type C-H Amidation of Purine Bases.
Topics: Adenine; Guanine; Guanosine; Nucleosides; Purine Nucleosides; Purines | 2022 |
Intermediate products of purine metabolism in an experimental model of pancreatic necrosis.
Topics: Adenine; Animals; Guanine; Hypoxanthine; Models, Theoretical; Pancreatitis, Acute Necrotizing; Purines; Rabbits; Uric Acid; Xanthine | 2022 |
Understanding the interaction of nucleotides with UVC light: an insight from quantum chemical calculation-based findings.
Topics: Adenine; Cytosine; Guanine; Nucleotides; Ultraviolet Rays; Uracil | 2023 |
The Influence of the Selection at the Amino Acid Level on Synonymous Codon Usage from the Viewpoint of Alternative Genetic Codes.
Topics: Adenine; Amino Acids; Codon; Codon Usage; Cytosine; Evolution, Molecular; Genetic Code; Guanine; Nucleotides; Selection, Genetic; Thymine | 2023 |
Bubble Relaxation Dynamics in Homopolymer DNA Sequences.
Topics: Adenine; Base Sequence; Computer Simulation; Cytosine; DNA; Guanine; Models, Chemical; Models, Molecular; Thymine | 2023 |
Aggregation of nucleobases and metabolites: Adenine-theobromine trimers.
Topics: Adenine; Cytosine; Guanine; Theobromine; Thymine | 2023 |
Charge transport properties of ideal and natural DNA segments, as mutation detectors.
Topics: Adenine; DNA; Guanine; Humans; Huntington Disease; Mutation | 2023 |
Efficient PAM-Less Base Editing for Zebrafish Modeling of Human Genetic Disease with zSpRY-ABE8e.
Topics: Adenine; Animals; Drug Evaluation, Preclinical; Gene Editing; Guanine; Humans; RNA, Guide, CRISPR-Cas Systems; Zebrafish | 2023 |
Interaction of Doxorubicin Embedded into Phospholipid Nanoparticles and Targeted Peptide-Modified Phospholipid Nanoparticles with DNA.
Topics: Adenine; DNA; Doxorubicin; Drug Delivery Systems; Guanine; Nanoparticles; Nanotubes, Carbon; Peptides; Phospholipids; Thymine | 2023 |
Different Patterns of Codon Usage and Amino Acid Composition across Primate Lentiviruses.
Topics: Adenine; Amino Acids; Animals; Codon; Codon Usage; Guanine; HIV-1; Lentivirus; Lentiviruses, Primate; Mammals | 2023 |
DNA Hairpins and Stabilization of Gold Nanoparticles: Effect of Stem Length and Toehold Composition.
Topics: Adenine; Colorimetry; DNA; Gold; Guanine; Metal Nanoparticles | 2023 |