Compounds > adenine

adenine and geldanamycin

adenine has been researched along with geldanamycin in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (66.67)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Kondo, S; Kondo, Y1
Ichikawa, S; Matsuda, A; Muranaka, K; Sano, A1
Boehm, MF; Brekken, J; Burrows, FJ; Busch, DJ; Friedman, J; Hong, K; Huser, N; Kamal, A; Kasibhatla, SR; Lundgren, K; McKenzie, A; Neely, L; Powell, RE; Scannevin, R; Sensintaffar, JL; Timple, N; Yang, YC; Zhang, H1
Fu, C; Ladbury, JE; Nilapwar, S; Pearl, LH; Prodromou, C; Williams, E; Williams, MA1
Luo, HM; Sun, W; Yang, XH; Yin, JY1

Reviews

1 review(s) available for adenine and geldanamycin

ArticleYear
[Progress in the study of heat shock protein 90 inhibitors].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2010, Volume: 45, Issue:7

    Topics: Adenine; Animals; Anisoles; Antineoplastic Agents; Benzoquinones; Catechin; Cell Line, Tumor; Crystallization; Heterocyclic Compounds, 2-Ring; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Macrolides; Molecular Structure; Neoplasms; Pyrazoles; Structure-Activity Relationship

2010

Other Studies

5 other study(ies) available for adenine and geldanamycin

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
American Association for Cancer Research--97th annual meeting.
    IDrugs : the investigational drugs journal, 2006, Volume: 9, Issue:6

    Topics: Adenine; Animals; Antineoplastic Agents; Benzoquinones; Glioblastoma; HSP90 Heat-Shock Proteins; Humans; Indoles; Janus Kinase 2; Lactams, Macrocyclic; Neoplasms, Experimental; Organophosphonates; Protein Kinase C; Protein Kinase Inhibitors; Signal Transduction; Topotecan; Tyrphostins

2006
Synthesis of Hsp90 inhibitor dimers as potential antitumor agents.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Adenine; Anisoles; Antineoplastic Agents; Benzoquinones; Breast Neoplasms; Cell Line, Tumor; Dimerization; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Macrolides; Peptide Fragments

2008
BIIB021, an orally available, fully synthetic small-molecule inhibitor of the heat shock protein Hsp90.
    Molecular cancer therapeutics, 2009, Volume: 8, Issue:4

    Topics: Adenine; Administration, Oral; Animals; Antineoplastic Agents; Benzoquinones; Blotting, Western; Cell Proliferation; Chromatography, High Pressure Liquid; HSP27 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms, Experimental; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-raf; Pyridines; Receptor, ErbB-2; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2009
Structural-thermodynamic relationships of interactions in the N-terminal ATP-binding domain of Hsp90.
    Journal of molecular biology, 2009, Oct-02, Volume: 392, Issue:4

    Topics: Adenine; Adenosine Triphosphate; Benzoquinones; Binding Sites; Calorimetry, Differential Scanning; HSP90 Heat-Shock Proteins; Lactams, Macrocyclic; Models, Biological; Models, Molecular; Protein Binding; Protein Structure, Tertiary; Saccharomyces cerevisiae; Structure-Activity Relationship; Temperature; Thermodynamics

2009