adenine and ganciclovir

adenine has been researched along with ganciclovir in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19902 (7.69)18.7374
1990's12 (46.15)18.2507
2000's10 (38.46)29.6817
2010's2 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Andrei, G; De Clercq, E; Neyts, J; Schols, D; Snoeck, R1
De Castro, LM; De Clercq, E; Gangemi, JD; Ghaffar, A; Kern, ER; Mayer, EP; Vogt, PE1
Baba, M; De Clercq, E; Konno, K; Shigeta, S; Yokota, T1
Domin, BA; Mahony, WB; Zimmerman, TP1
Balzarini, J; Bron, D; De Clercq, E; Delforge, A; Lagneaux, L; Snoeck, R; Stryckmans, P; Van der Auwera, P1
Azuma, M; Sakuma, T1
Fujioka, H; Nishiyama, Y; Shimada, N; Takahashi, K; Yamada, Y; Yamamoto, N1
De Clercq, E; Neyts, J1
Mimura, Y; Naito, T; Nitta, K; Shiota, H1
Balzarini, J; De Clercq, E; Dvoráková, H; Holý, A; Naesens, L; Reymen, D1
De Clercq, E; Kodama, E; Shigeta, S; Suzuki, T1
Balzarini, J; de Clercq, E; de Vries, E; Franssen, FF; Holý, A; Naesens, L; Overdulve, JP; Smeijsters, LJ1
Hartline, CB; Kern, ER; Qiu, YL; Rybak, RJ; Zemlicka, J1
Hoffman, VF; Skiest, DJ1
Cadman, J1
de Man, RA; Niesters, HG; Wolters, LM1
Perrillo, RP1
Baldanti, F; Drach, JC; Gerna, G; Sarasini, A; Zemlicka, J1
Vere Hodge, A1
Majumdar, S; Mitra, AK; Pal, D; Tirucherai, GS1
Choi, BG; Hong, JH; Kwak, EY; Park, Y1
Fridland, A; Olson, L; Ray, AS1
Morton, CJ; Ng, HL; Parker, MW; Rawlinson, WD; Scott, GM1
Croubels, S; De Backer, P; Garré, B; Nauwynck, H; Neyts, J; Nugent, J; van der Meulen, K1
Razonable, RR1

Reviews

4 review(s) available for adenine and ganciclovir

ArticleYear
Therapeutic developments in cytomegalovirus retinitis.
    Expert opinion on investigational drugs, 2000, Volume: 9, Issue:2

    Topics: Adenine; Antibodies, Monoclonal; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drugs, Investigational; Foscarnet; Ganciclovir; Guanine; Humans; Organophosphonates; Organophosphorus Compounds; Thionucleotides; Valganciclovir

2000
Nucleoside analogues for chronic hepatitis B.
    European journal of gastroenterology & hepatology, 2001, Volume: 13, Issue:12

    Topics: 2-Aminopurine; Adenine; Antiviral Agents; Famciclovir; Ganciclovir; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Organophosphonates; Reverse Transcriptase Inhibitors

2001
How will we use the new antiviral agents for hepatitis B?
    Current gastroenterology reports, 2002, Volume: 4, Issue:1

    Topics: 2-Aminopurine; Adenine; Alanine Transaminase; Antiviral Agents; Drug Resistance; Drug Therapy, Combination; Famciclovir; Ganciclovir; Gene Products, pol; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Mutation; Organophosphonates; Practice Guidelines as Topic

2002
Antiviral drugs for viruses other than human immunodeficiency virus.
    Mayo Clinic proceedings, 2011, Volume: 86, Issue:10

    Topics: Acyclovir; Adenine; Amantadine; Antiviral Agents; Comorbidity; Drug Therapy, Combination; Foscarnet; Ganciclovir; Guanine; Hepatitis; Hepatitis B, Chronic; Hepatitis C; Herpesviridae Infections; HIV Infections; Humans; Influenza, Human; Interferons; Lamivudine; Nucleosides; Oligopeptides; Organophosphonates; Oseltamivir; Proline; Protease Inhibitors; Pyrimidinones; Ribavirin; Telbivudine; Thymidine; Valacyclovir; Valganciclovir; Valine; Virus Replication; Zanamivir

2011

Other Studies

22 other study(ies) available for adenine and ganciclovir

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Antiviral activity of anti-cytomegalovirus agents (HPMPC, HPMPA) assessed by a flow cytometric method and DNA hybridization technique.
    Antiviral research, 1991, Volume: 16, Issue:1

    Topics: Adenine; Antiviral Agents; Cell Line; Cidofovir; Cytomegalovirus; Cytosine; Flow Cytometry; Ganciclovir; Humans; Microbial Sensitivity Tests; Nucleic Acid Hybridization; Organophosphonates; Organophosphorus Compounds; Viral Plaque Assay

1991
Phosphonylmethoxyalkyl purine and pyrimidine derivatives for treatment of opportunistic cytomegalovirus and herpes simplex virus infections in murine AIDS.
    Antiviral research, 1991, Volume: 16, Issue:1

    Topics: Adenine; Animals; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Ganciclovir; Herpes Simplex; Immune Tolerance; Mice; Mice, Inbred C57BL; Murine Acquired Immunodeficiency Syndrome; Opportunistic Infections; Organophosphonates; Organophosphorus Compounds

1991
Comparative inhibitory effects of nucleoside analogues on different clinical isolates of human cytomegalovirus in vitro.
    The Journal of infectious diseases, 1991, Volume: 163, Issue:2

    Topics: Adenine; Adenosine; Antiviral Agents; Cell Line; Cidofovir; Cytidine; Cytomegalovirus; Cytosine; Ganciclovir; Guanosine; Humans; Nucleosides; Organophosphonates; Organophosphorus Compounds; Thymidine

1991
Ganciclovir permeation of the human erythrocyte membrane.
    Biochemical pharmacology, 1991, Jan-15, Volume: 41, Issue:2

    Topics: Acyclovir; Adenine; Biological Transport; Carrier Proteins; Cell Membrane Permeability; Dilazep; Dose-Response Relationship, Drug; Erythrocyte Membrane; Ganciclovir; Humans; Idoxuridine; Kinetics; Membrane Proteins; Nucleoside Transport Proteins; Purines

1991
Inhibitory effects of potent inhibitors of human immunodeficiency virus and cytomegalovirus on the growth of human granulocyte-macrophage progenitor cells in vitro.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1990, Volume: 9, Issue:8

    Topics: Adenine; Adult; Antiviral Agents; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Foscarnet; Ganciclovir; Granulocytes; Hematopoietic Stem Cells; HIV; Humans; Macrophages; Organophosphonates; Organophosphorus Compounds; Phosphonoacetic Acid; Zidovudine

1990
[Chemotherapy of cytomegalovirus infections].
    Nihon rinsho. Japanese journal of clinical medicine, 1989, Volume: 47, Issue:2

    Topics: Acyclovir; Adenine; Cytomegalovirus Infections; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; Phosphonoacetic Acid

1989
Efficacy of oxetanocin G against herpes simplex virus type 2 and murine cytomegalovirus infections in mice.
    The Journal of antibiotics, 1989, Volume: 42, Issue:8

    Topics: Acyclovir; Adenine; Animals; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Disease Models, Animal; Ganciclovir; Guanine; Herpes Simplex; Male; Mice; Mice, Inbred ICR; Prodrugs

1989
New inhibitors of cytomegalovirus replication: in vitro evaluation, mechanism of action, and in vivo activity.
    Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie, 1994, Volume: 56, Issue:6

    Topics: Adenine; Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA, Viral; Ganciclovir; Herpesviridae Infections; Humans; Immunologic Deficiency Syndromes; Mice; Mice, SCID; Muromegalovirus; Organophosphonates; Organophosphorus Compounds; Virus Replication

1994
[Sensitivities to other antiviral drugs and thymidine kinase activity of aciclovir-resistant herpes simplex virus type 1].
    Nippon Ganka Gakkai zasshi, 1994, Volume: 98, Issue:6

    Topics: Acyclovir; Adenine; Antiviral Agents; Drug Resistance, Microbial; Ganciclovir; Guanine; Herpesvirus 1, Human; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Thymidine Kinase; Vidarabine

1994
Antiviral activity of selected acyclic nucleoside analogues against human herpesvirus 6.
    Antiviral research, 1995, Volume: 28, Issue:4

    Topics: Adenine; Antiviral Agents; Cell Line; Cidofovir; Cytopathogenic Effect, Viral; Cytosine; Flow Cytometry; Foscarnet; Ganciclovir; Herpesvirus 6, Human; Humans; Nucleosides; Organophosphonates; Organophosphorus Compounds

1995
Application of a gastric cancer cell line (MKN-28) for anti-adenovirus screening using the MTT method.
    Antiviral research, 1996, Volume: 31, Issue:3

    Topics: Adenine; Adenoviruses, Human; Antiviral Agents; Cidofovir; Cytosine; Drug Evaluation, Preclinical; Formazans; Ganciclovir; Humans; Idoxuridine; Organophosphonates; Organophosphorus Compounds; Purines; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured

1996
Inhibition of the in vitro growth of Plasmodium falciparum by acyclic nucleoside phosphonates.
    International journal of antimicrobial agents, 1999, Volume: 12, Issue:1

    Topics: Adenine; Animals; Antimalarials; Cidofovir; Cytosine; Erythrocytes; Ganciclovir; Humans; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Organophosphorus Compounds; Plasmodium falciparum; Structure-Activity Relationship

1999
Effective treatment of murine cytomegalovirus infections with methylenecyclopropane analogues of nucleosides.
    Antiviral research, 1999, Volume: 43, Issue:3

    Topics: Adenine; Administration, Oral; Animals; Antiviral Agents; Cells, Cultured; Cyclopropanes; Cytomegalovirus; Cytomegalovirus Infections; Ganciclovir; Humans; Mice; Mice, Inbred BALB C; Nucleosides; Viral Plaque Assay

1999
CMV trials struggle to enroll.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1997, Volume: 11, Issue:9

    Topics: Adenine; AIDS-Related Opportunistic Infections; Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Cytomegalovirus Infections; Ganciclovir; Humans; Prodrugs

1997
Z-isomers of 2-hydroxymethylcyclopropylidenemethyl adenine (synadenol) and guanine (synguanol) are active against ganciclovir- and foscarnet-resistant human cytomegalovirus UL97 mutants.
    Antiviral research, 2002, Volume: 56, Issue:3

    Topics: Adenine; Antiviral Agents; Cyclopropanes; Cytomegalovirus; Cytomegalovirus Infections; Drug Resistance, Viral; Foscarnet; Ganciclovir; Guanine; Humans; Immunocompromised Host; Phosphotransferases (Alcohol Group Acceptor)

2002
Antiviral Research--16th Annual International Conference. Satellite symposium: clinical update on antiviral drugs. 27 April-1 May 2003, Savannah, GA, USA.
    IDrugs : the investigational drugs journal, 2003, Volume: 6, Issue:6

    Topics: Adenine; Anti-HIV Agents; Antiviral Agents; Clinical Trials as Topic; Enfuvirtide; Ganciclovir; Hepatitis B; HIV Envelope Protein gp41; HIV Infections; Humans; Organophosphonates; Organophosphorus Compounds; Peptide Fragments; Tenofovir; Valganciclovir

2003
Functional differences in nucleoside and nucleobase transporters expressed on the rabbit corneal epithelial cell line (SIRC) and isolated rabbit cornea.
    AAPS pharmSci, 2003, Volume: 5, Issue:2

    Topics: Adenine; Animals; Biological Transport; Cornea; Epithelium, Corneal; Ganciclovir; Male; Membrane Transport Proteins; Nucleosides; Nucleotide Transport Proteins; Rabbits; Sodium; Thioinosine; Thymidine; Tritium

2003
Synthesis and antiviral activity of novel C-methyl branched cyclopropyl nucleosides.
    Archives of pharmacal research, 2003, Volume: 26, Issue:9

    Topics: Adenine; Antiviral Agents; Crystallography, X-Ray; Cyclization; Cyclopropanes; Cytomegalovirus; Cytotoxicity Tests, Immunologic; Ganciclovir; Herpesvirus 1, Human; HIV-1; Korea; Magnetic Resonance Spectroscopy; Methylation; Molecular Structure; Purine Nucleosides; Purines; Ribavirin; Zidovudine

2003
Role of purine nucleoside phosphorylase in interactions between 2',3'-dideoxyinosine and allopurinol, ganciclovir, or tenofovir.
    Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:4

    Topics: Adenine; Allopurinol; Anti-HIV Agents; Antimetabolites; Antiviral Agents; Biotransformation; Caco-2 Cells; Chromatography, High Pressure Liquid; Didanosine; Drug Interactions; Enzyme Inhibitors; Ganciclovir; Humans; Intestinal Absorption; Kinetics; Organophosphonates; Organophosphorus Compounds; Permeability; Purine-Nucleoside Phosphorylase; Substrate Specificity; Tenofovir

2004
Murine cytomegalovirus resistant to antivirals has genetic correlates with human cytomegalovirus.
    The Journal of general virology, 2005, Volume: 86, Issue:Pt 8

    Topics: Acyclovir; Adenine; Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Ganciclovir; Guanine; Humans; Mice; Models, Molecular; Molecular Sequence Data; Muromegalovirus; Mutation; Organophosphonates; Protein Kinases; Sequence Alignment; Valacyclovir; Valine; Virus Replication

2005
In vitro susceptibility of six isolates of equine herpesvirus 1 to acyclovir, ganciclovir, cidofovir, adefovir, PMEDAP and foscarnet.
    Veterinary microbiology, 2007, May-16, Volume: 122, Issue:1-2

    Topics: Acyclovir; Adenine; Animals; Antiviral Agents; Cell Survival; Cells, Cultured; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Drug Resistance, Viral; Epithelial Cells; Foscarnet; Ganciclovir; Herpesvirus 1, Equid; Horses; Lung; Organophosphonates

2007